id	sid	tid	token	lemma	pos
cord-257662-viy65y72	1	1	key	key	JJ
cord-257662-viy65y72	2	1	:	:	:
cord-257662-viy65y72	2	2	cord-257662-viy65y72	cord-257662-viy65y72	NNP
cord-257662-viy65y72	2	3	authors	author	NNS
cord-257662-viy65y72	2	4	:	:	:
cord-257662-viy65y72	2	5	Burrack	Burrack	NNP
cord-257662-viy65y72	2	6	,	,	,
cord-257662-viy65y72	2	7	Kristina	Kristina	NNP
cord-257662-viy65y72	2	8	S.	S.	NNP
cord-257662-viy65y72	2	9	;	;	:
cord-257662-viy65y72	2	10	Morrison	Morrison	NNP
cord-257662-viy65y72	2	11	,	,	,
cord-257662-viy65y72	3	1	Thomas	Thomas	NNP
cord-257662-viy65y72	3	2	E.	E.	NNP
cord-257662-viy65y72	3	3	title	title	NN
cord-257662-viy65y72	3	4	:	:	:
cord-257662-viy65y72	4	1	The	the	DT
cord-257662-viy65y72	4	2	Role	role	NN
cord-257662-viy65y72	4	3	of	of	IN
cord-257662-viy65y72	4	4	Myeloid	Myeloid	NNP
cord-257662-viy65y72	4	5	Cell	Cell	NNP
cord-257662-viy65y72	4	6	Activation	Activation	NNP
cord-257662-viy65y72	4	7	and	and	CC
cord-257662-viy65y72	4	8	Arginine	Arginine	NNP
cord-257662-viy65y72	4	9	Metabolism	metabolism	NN
cord-257662-viy65y72	4	10	in	in	IN
cord-257662-viy65y72	4	11	the	the	DT
cord-257662-viy65y72	4	12	Pathogenesis	Pathogenesis	NNP
cord-257662-viy65y72	4	13	of	of	IN
cord-257662-viy65y72	4	14	Virus	Virus	NNP
cord-257662-viy65y72	4	15	-	-	HYPH
cord-257662-viy65y72	4	16	Induced	induce	VBN
cord-257662-viy65y72	4	17	Diseases	Diseases	NNPS
cord-257662-viy65y72	4	18	date	date	NN
cord-257662-viy65y72	4	19	:	:	:
cord-257662-viy65y72	4	20	2014	2014	CD
cord-257662-viy65y72	4	21	-	-	HYPH
cord-257662-viy65y72	4	22	09	09	CD
cord-257662-viy65y72	4	23	-	-	HYPH
cord-257662-viy65y72	4	24	08	08	CD
cord-257662-viy65y72	4	25	journal	journal	NN
cord-257662-viy65y72	4	26	:	:	:
cord-257662-viy65y72	5	1	Front	Front	NNP
cord-257662-viy65y72	5	2	Immunol	Immunol	NNP
cord-257662-viy65y72	5	3	DOI	DOI	NNP
cord-257662-viy65y72	5	4	:	:	:
cord-257662-viy65y72	5	5	10.3389	10.3389	CD
cord-257662-viy65y72	5	6	/	/	SYM
cord-257662-viy65y72	5	7	fimmu.2014.00428	fimmu.2014.00428	NN
cord-257662-viy65y72	5	8	sha	sha	NNP
cord-257662-viy65y72	5	9	:	:	:
cord-257662-viy65y72	5	10	94ba61be5805b1b0caef6716c00ed234be78b021	94ba61be5805b1b0caef6716c00ed234be78b021	NNP
cord-257662-viy65y72	5	11	doc_id	doc_id	NNP
cord-257662-viy65y72	5	12	:	:	:
cord-257662-viy65y72	5	13	257662	257662	CD
cord-257662-viy65y72	5	14	cord_uid	cord_uid	NNS
cord-257662-viy65y72	5	15	:	:	:
cord-257662-viy65y72	6	1	viy65y72	viy65y72	NFP
cord-257662-viy65y72	7	1	When	when	WRB
cord-257662-viy65y72	7	2	an	an	DT
cord-257662-viy65y72	7	3	antiviral	antiviral	JJ
cord-257662-viy65y72	7	4	immune	immune	JJ
cord-257662-viy65y72	7	5	response	response	NN
cord-257662-viy65y72	7	6	is	be	VBZ
cord-257662-viy65y72	7	7	generated	generate	VBN
cord-257662-viy65y72	7	8	,	,	,
cord-257662-viy65y72	7	9	a	a	DT
cord-257662-viy65y72	7	10	balance	balance	NN
cord-257662-viy65y72	7	11	must	must	MD
cord-257662-viy65y72	7	12	be	be	VB
cord-257662-viy65y72	7	13	reached	reach	VBN
cord-257662-viy65y72	7	14	between	between	IN
cord-257662-viy65y72	7	15	two	two	CD
cord-257662-viy65y72	7	16	opposing	oppose	VBG
cord-257662-viy65y72	7	17	pathways	pathway	NNS
cord-257662-viy65y72	7	18	:	:	:
cord-257662-viy65y72	7	19	the	the	DT
cord-257662-viy65y72	7	20	production	production	NN
cord-257662-viy65y72	7	21	of	of	IN
cord-257662-viy65y72	7	22	proinflammatory	proinflammatory	JJ
cord-257662-viy65y72	7	23	and	and	CC
cord-257662-viy65y72	7	24	cytotoxic	cytotoxic	JJ
cord-257662-viy65y72	7	25	effectors	effector	NNS
cord-257662-viy65y72	7	26	that	that	WDT
cord-257662-viy65y72	7	27	drive	drive	VBP
cord-257662-viy65y72	7	28	a	a	DT
cord-257662-viy65y72	7	29	robust	robust	JJ
cord-257662-viy65y72	7	30	antiviral	antiviral	JJ
cord-257662-viy65y72	7	31	immune	immune	JJ
cord-257662-viy65y72	7	32	response	response	NN
cord-257662-viy65y72	7	33	to	to	TO
cord-257662-viy65y72	7	34	control	control	VB
cord-257662-viy65y72	7	35	the	the	DT
cord-257662-viy65y72	7	36	infection	infection	NN
cord-257662-viy65y72	7	37	and	and	CC
cord-257662-viy65y72	7	38	regulators	regulator	NNS
cord-257662-viy65y72	7	39	that	that	WDT
cord-257662-viy65y72	7	40	function	function	VBP
cord-257662-viy65y72	7	41	to	to	TO
cord-257662-viy65y72	7	42	limit	limit	VB
cord-257662-viy65y72	7	43	or	or	CC
cord-257662-viy65y72	7	44	blunt	blunt	VB
cord-257662-viy65y72	7	45	an	an	DT
cord-257662-viy65y72	7	46	excessive	excessive	JJ
cord-257662-viy65y72	7	47	immune	immune	JJ
cord-257662-viy65y72	7	48	response	response	NN
cord-257662-viy65y72	7	49	to	to	TO
cord-257662-viy65y72	7	50	minimize	minimize	VB
cord-257662-viy65y72	7	51	immune	immune	NN
cord-257662-viy65y72	7	52	-	-	HYPH
cord-257662-viy65y72	7	53	mediated	mediate	VBN
cord-257662-viy65y72	7	54	pathology	pathology	NN
cord-257662-viy65y72	7	55	and	and	CC
cord-257662-viy65y72	7	56	repair	repair	NN
cord-257662-viy65y72	7	57	tissue	tissue	NN
cord-257662-viy65y72	7	58	damage	damage	NN
cord-257662-viy65y72	7	59	.	.	.
cord-257662-viy65y72	8	1	Myeloid	myeloid	NN
cord-257662-viy65y72	8	2	cells	cell	NNS
cord-257662-viy65y72	8	3	,	,	,
cord-257662-viy65y72	8	4	including	include	VBG
cord-257662-viy65y72	8	5	monocytes	monocyte	NNS
cord-257662-viy65y72	8	6	and	and	CC
cord-257662-viy65y72	8	7	macrophages	macrophage	NNS
cord-257662-viy65y72	8	8	,	,	,
cord-257662-viy65y72	8	9	play	play	VB
cord-257662-viy65y72	8	10	an	an	DT
cord-257662-viy65y72	8	11	important	important	JJ
cord-257662-viy65y72	8	12	role	role	NN
cord-257662-viy65y72	8	13	in	in	IN
cord-257662-viy65y72	8	14	this	this	DT
cord-257662-viy65y72	8	15	balance	balance	NN
cord-257662-viy65y72	8	16	,	,	,
cord-257662-viy65y72	8	17	particularly	particularly	RB
cord-257662-viy65y72	8	18	through	through	IN
cord-257662-viy65y72	8	19	the	the	DT
cord-257662-viy65y72	8	20	activities	activity	NNS
cord-257662-viy65y72	8	21	of	of	IN
cord-257662-viy65y72	8	22	the	the	DT
cord-257662-viy65y72	8	23	arginine	arginine	NN
cord-257662-viy65y72	8	24	-	-	HYPH
cord-257662-viy65y72	8	25	hydrolyzing	hydrolyze	VBG
cord-257662-viy65y72	8	26	enzymes	enzyme	NNS
cord-257662-viy65y72	8	27	nitric	nitric	JJ
cord-257662-viy65y72	8	28	oxide	oxide	NN
cord-257662-viy65y72	8	29	synthase	synthase	NN
cord-257662-viy65y72	8	30	2	2	CD
cord-257662-viy65y72	9	1	(	(	-LRB-
cord-257662-viy65y72	9	2	Nos2	Nos2	NNP
cord-257662-viy65y72	9	3	;	;	,
cord-257662-viy65y72	9	4	iNOS	inos	CD
cord-257662-viy65y72	9	5	)	)	-RRB-
cord-257662-viy65y72	10	1	and	and	CC
cord-257662-viy65y72	10	2	arginase	arginase	NNP
cord-257662-viy65y72	10	3	1	1	CD
cord-257662-viy65y72	10	4	(	(	-LRB-
cord-257662-viy65y72	10	5	Arg1	Arg1	NNP
cord-257662-viy65y72	10	6	)	)	-RRB-
cord-257662-viy65y72	10	7	.	.	.
cord-257662-viy65y72	11	1	Nitric	nitric	NN
cord-257662-viy65y72	11	2	oxide	oxide	NN
cord-257662-viy65y72	11	3	(	(	-LRB-
cord-257662-viy65y72	11	4	NO	no	UH
cord-257662-viy65y72	11	5	)	)	-RRB-
cord-257662-viy65y72	11	6	production	production	NN
cord-257662-viy65y72	11	7	by	by	IN
cord-257662-viy65y72	11	8	iNOS	inos	NN
cord-257662-viy65y72	11	9	is	be	VBZ
cord-257662-viy65y72	11	10	an	an	DT
cord-257662-viy65y72	11	11	important	important	JJ
cord-257662-viy65y72	11	12	proinflammatory	proinflammatory	JJ
cord-257662-viy65y72	11	13	mediator	mediator	NN
cord-257662-viy65y72	11	14	,	,	,
cord-257662-viy65y72	11	15	whereas	whereas	IN
cord-257662-viy65y72	11	16	Arg1-expressing	Arg1-expressing	NNP
cord-257662-viy65y72	11	17	macrophages	macrophage	NNS
cord-257662-viy65y72	11	18	contribute	contribute	VBP
cord-257662-viy65y72	11	19	to	to	IN
cord-257662-viy65y72	11	20	the	the	DT
cord-257662-viy65y72	11	21	resolution	resolution	NN
cord-257662-viy65y72	11	22	of	of	IN
cord-257662-viy65y72	11	23	inflammation	inflammation	NN
cord-257662-viy65y72	11	24	and	and	CC
cord-257662-viy65y72	11	25	wound	wound	VB
cord-257662-viy65y72	11	26	repair	repair	NN
cord-257662-viy65y72	11	27	.	.	.
cord-257662-viy65y72	12	1	In	in	IN
cord-257662-viy65y72	12	2	the	the	DT
cord-257662-viy65y72	12	3	context	context	NN
cord-257662-viy65y72	12	4	of	of	IN
cord-257662-viy65y72	12	5	viral	viral	JJ
cord-257662-viy65y72	12	6	infections	infection	NNS
cord-257662-viy65y72	12	7	,	,	,
cord-257662-viy65y72	12	8	expression	expression	NN
cord-257662-viy65y72	12	9	of	of	IN
cord-257662-viy65y72	12	10	these	these	DT
cord-257662-viy65y72	12	11	enzymes	enzyme	NNS
cord-257662-viy65y72	12	12	can	can	MD
cord-257662-viy65y72	12	13	result	result	VB
cord-257662-viy65y72	12	14	in	in	IN
cord-257662-viy65y72	12	15	a	a	DT
cord-257662-viy65y72	12	16	variety	variety	NN
cord-257662-viy65y72	12	17	of	of	IN
cord-257662-viy65y72	12	18	outcomes	outcome	NNS
cord-257662-viy65y72	12	19	for	for	IN
cord-257662-viy65y72	12	20	the	the	DT
cord-257662-viy65y72	12	21	host	host	NN
cord-257662-viy65y72	12	22	.	.	.
cord-257662-viy65y72	13	1	NO	no	UH
cord-257662-viy65y72	13	2	has	have	VBZ
cord-257662-viy65y72	13	3	direct	direct	JJ
cord-257662-viy65y72	13	4	antiviral	antiviral	JJ
cord-257662-viy65y72	13	5	properties	property	NNS
cord-257662-viy65y72	13	6	against	against	IN
cord-257662-viy65y72	13	7	some	some	DT
cord-257662-viy65y72	13	8	viruses	virus	NNS
cord-257662-viy65y72	13	9	,	,	,
cord-257662-viy65y72	13	10	whereas	whereas	IN
cord-257662-viy65y72	13	11	during	during	IN
cord-257662-viy65y72	13	12	other	other	JJ
cord-257662-viy65y72	13	13	virus	virus	NN
cord-257662-viy65y72	13	14	infections	infection	NNS
cord-257662-viy65y72	13	15	NO	no	RB
cord-257662-viy65y72	13	16	can	can	MD
cord-257662-viy65y72	13	17	mediate	mediate	VB
cord-257662-viy65y72	13	18	immunopathology	immunopathology	NN
cord-257662-viy65y72	14	1	and/or	and/or	CC
cord-257662-viy65y72	14	2	inhibit	inhibit	VB
cord-257662-viy65y72	14	3	the	the	DT
cord-257662-viy65y72	14	4	antiviral	antiviral	JJ
cord-257662-viy65y72	14	5	immune	immune	JJ
cord-257662-viy65y72	14	6	response	response	NN
cord-257662-viy65y72	14	7	to	to	TO
cord-257662-viy65y72	14	8	promote	promote	VB
cord-257662-viy65y72	14	9	chronic	chronic	JJ
cord-257662-viy65y72	14	10	infection	infection	NN
cord-257662-viy65y72	14	11	.	.	.
cord-257662-viy65y72	15	1	Arg1	arg1	JJ
cord-257662-viy65y72	15	2	activity	activity	NN
cord-257662-viy65y72	15	3	not	not	RB
cord-257662-viy65y72	15	4	only	only	RB
cord-257662-viy65y72	15	5	has	have	VBZ
cord-257662-viy65y72	15	6	important	important	JJ
cord-257662-viy65y72	15	7	wound	wound	NN
cord-257662-viy65y72	15	8	healing	healing	NN
cord-257662-viy65y72	15	9	functions	function	NNS
cord-257662-viy65y72	15	10	but	but	CC
cord-257662-viy65y72	15	11	can	can	MD
cord-257662-viy65y72	15	12	also	also	RB
cord-257662-viy65y72	15	13	inhibit	inhibit	VB
cord-257662-viy65y72	15	14	the	the	DT
cord-257662-viy65y72	15	15	antiviral	antiviral	JJ
cord-257662-viy65y72	15	16	immune	immune	JJ
cord-257662-viy65y72	15	17	response	response	NN
cord-257662-viy65y72	15	18	during	during	IN
cord-257662-viy65y72	15	19	some	some	DT
cord-257662-viy65y72	15	20	viral	viral	JJ
cord-257662-viy65y72	15	21	infections	infection	NNS
cord-257662-viy65y72	15	22	.	.	.
cord-257662-viy65y72	16	1	Thus	thus	RB
cord-257662-viy65y72	16	2	,	,	,
cord-257662-viy65y72	16	3	depending	depend	VBG
cord-257662-viy65y72	16	4	on	on	IN
cord-257662-viy65y72	16	5	the	the	DT
cord-257662-viy65y72	16	6	specific	specific	JJ
cord-257662-viy65y72	16	7	virus	virus	NN
cord-257662-viy65y72	16	8	and	and	CC
cord-257662-viy65y72	16	9	the	the	DT
cord-257662-viy65y72	16	10	tissue(s	tissue(s	NN
cord-257662-viy65y72	16	11	)	)	-RRB-
cord-257662-viy65y72	16	12	involved	involve	VBN
cord-257662-viy65y72	16	13	,	,	,
cord-257662-viy65y72	16	14	the	the	DT
cord-257662-viy65y72	16	15	activity	activity	NN
cord-257662-viy65y72	16	16	of	of	IN
cord-257662-viy65y72	16	17	both	both	DT
cord-257662-viy65y72	16	18	of	of	IN
cord-257662-viy65y72	16	19	these	these	DT
cord-257662-viy65y72	16	20	arginine	arginine	NN
cord-257662-viy65y72	16	21	-	-	HYPH
cord-257662-viy65y72	16	22	hydrolyzing	hydrolyze	VBG
cord-257662-viy65y72	16	23	enzymes	enzyme	NNS
cord-257662-viy65y72	16	24	can	can	MD
cord-257662-viy65y72	16	25	either	either	CC
cord-257662-viy65y72	16	26	exacerbate	exacerbate	VB
cord-257662-viy65y72	16	27	or	or	CC
cord-257662-viy65y72	16	28	limit	limit	VB
cord-257662-viy65y72	16	29	the	the	DT
cord-257662-viy65y72	16	30	severity	severity	NN
cord-257662-viy65y72	16	31	of	of	IN
cord-257662-viy65y72	16	32	virus	virus	NN
cord-257662-viy65y72	16	33	-	-	HYPH
cord-257662-viy65y72	16	34	induced	induce	VBN
cord-257662-viy65y72	16	35	disease	disease	NN
cord-257662-viy65y72	16	36	.	.	.
cord-257662-viy65y72	17	1	In	in	IN
cord-257662-viy65y72	17	2	this	this	DT
cord-257662-viy65y72	17	3	review	review	NN
cord-257662-viy65y72	17	4	,	,	,
cord-257662-viy65y72	17	5	we	-PRON-	PRP
cord-257662-viy65y72	17	6	will	will	MD
cord-257662-viy65y72	17	7	discuss	discuss	VB
cord-257662-viy65y72	17	8	a	a	DT
cord-257662-viy65y72	17	9	variety	variety	NN
cord-257662-viy65y72	17	10	of	of	IN
cord-257662-viy65y72	17	11	viral	viral	JJ
cord-257662-viy65y72	17	12	infections	infection	NNS
cord-257662-viy65y72	17	13	,	,	,
cord-257662-viy65y72	17	14	including	include	VBG
cord-257662-viy65y72	17	15	HIV	HIV	NNP
cord-257662-viy65y72	17	16	,	,	,
cord-257662-viy65y72	17	17	SARS	SARS	NNP
cord-257662-viy65y72	17	18	-	-	HYPH
cord-257662-viy65y72	17	19	CoV	CoV	NNP
cord-257662-viy65y72	17	20	,	,	,
cord-257662-viy65y72	17	21	LCMV	LCMV	NNP
cord-257662-viy65y72	17	22	,	,	,
cord-257662-viy65y72	17	23	HCV	HCV	NNP
cord-257662-viy65y72	17	24	,	,	,
cord-257662-viy65y72	17	25	RSV	RSV	NNP
cord-257662-viy65y72	17	26	,	,	,
cord-257662-viy65y72	17	27	and	and	CC
cord-257662-viy65y72	17	28	others	other	NNS
cord-257662-viy65y72	17	29	,	,	,
cord-257662-viy65y72	17	30	where	where	WRB
cord-257662-viy65y72	17	31	myeloid	myeloid	NN
cord-257662-viy65y72	17	32	cells	cell	NNS
cord-257662-viy65y72	17	33	influence	influence	VBP
cord-257662-viy65y72	17	34	the	the	DT
cord-257662-viy65y72	17	35	control	control	NN
cord-257662-viy65y72	17	36	and	and	CC
cord-257662-viy65y72	17	37	clearance	clearance	NN
cord-257662-viy65y72	17	38	of	of	IN
cord-257662-viy65y72	17	39	the	the	DT
cord-257662-viy65y72	17	40	virus	virus	NN
cord-257662-viy65y72	17	41	from	from	IN
cord-257662-viy65y72	17	42	the	the	DT
cord-257662-viy65y72	17	43	host	host	NN
cord-257662-viy65y72	17	44	,	,	,
cord-257662-viy65y72	17	45	as	as	RB
cord-257662-viy65y72	17	46	well	well	RB
cord-257662-viy65y72	17	47	as	as	IN
cord-257662-viy65y72	17	48	the	the	DT
cord-257662-viy65y72	17	49	severity	severity	NN
cord-257662-viy65y72	17	50	and	and	CC
cord-257662-viy65y72	17	51	resolution	resolution	NN
cord-257662-viy65y72	17	52	of	of	IN
cord-257662-viy65y72	17	53	tissue	tissue	NN
cord-257662-viy65y72	17	54	damage	damage	NN
cord-257662-viy65y72	17	55	,	,	,
cord-257662-viy65y72	17	56	via	via	IN
cord-257662-viy65y72	17	57	the	the	DT
cord-257662-viy65y72	17	58	activities	activity	NNS
cord-257662-viy65y72	17	59	of	of	IN
cord-257662-viy65y72	17	60	iNOS	inos	NN
cord-257662-viy65y72	17	61	and/or	and/or	CC
cord-257662-viy65y72	17	62	Arg1	Arg1	NNP
cord-257662-viy65y72	17	63	.	.	.
cord-257662-viy65y72	18	1	Clearly	clearly	RB
cord-257662-viy65y72	18	2	,	,	,
cord-257662-viy65y72	18	3	monocyte	monocyte	NNP
cord-257662-viy65y72	18	4	/	/	SYM
cord-257662-viy65y72	18	5	macrophage	macrophage	NN
cord-257662-viy65y72	18	6	activation	activation	NN
cord-257662-viy65y72	18	7	and	and	CC
cord-257662-viy65y72	18	8	arginine	arginine	NN
cord-257662-viy65y72	18	9	metabolism	metabolism	NN
cord-257662-viy65y72	18	10	will	will	MD
cord-257662-viy65y72	18	11	continue	continue	VB
cord-257662-viy65y72	18	12	to	to	TO
cord-257662-viy65y72	18	13	be	be	VB
cord-257662-viy65y72	18	14	important	important	JJ
cord-257662-viy65y72	18	15	areas	area	NNS
cord-257662-viy65y72	18	16	of	of	IN
cord-257662-viy65y72	18	17	investigation	investigation	NN
cord-257662-viy65y72	18	18	in	in	IN
cord-257662-viy65y72	18	19	the	the	DT
cord-257662-viy65y72	18	20	context	context	NN
cord-257662-viy65y72	18	21	of	of	IN
cord-257662-viy65y72	18	22	viral	viral	JJ
cord-257662-viy65y72	18	23	infections	infection	NNS
cord-257662-viy65y72	18	24	.	.	.
cord-257662-viy65y72	19	1	Tissue	tissue	NN
cord-257662-viy65y72	19	2	-resident	-resident	NN
cord-257662-viy65y72	19	3	and	and	CC
cord-257662-viy65y72	19	4	monocyte	monocyte	NN
cord-257662-viy65y72	19	5	-	-	HYPH
cord-257662-viy65y72	19	6	derived	derive	VBN
cord-257662-viy65y72	19	7	macrophages	macrophage	NNS
cord-257662-viy65y72	19	8	are	be	VBP
cord-257662-viy65y72	19	9	innate	innate	JJ
cord-257662-viy65y72	19	10	immune	immune	JJ
cord-257662-viy65y72	19	11	cells	cell	NNS
cord-257662-viy65y72	19	12	that	that	WDT
cord-257662-viy65y72	19	13	play	play	VBP
cord-257662-viy65y72	19	14	a	a	DT
cord-257662-viy65y72	19	15	key	key	JJ
cord-257662-viy65y72	19	16	role	role	NN
cord-257662-viy65y72	19	17	in	in	IN
cord-257662-viy65y72	19	18	normal	normal	JJ
cord-257662-viy65y72	19	19	tissue	tissue	NN
cord-257662-viy65y72	19	20	homeostasis	homeostasis	NN
cord-257662-viy65y72	19	21	,	,	,
cord-257662-viy65y72	19	22	presentation	presentation	NN
cord-257662-viy65y72	19	23	of	of	IN
cord-257662-viy65y72	19	24	foreign	foreign	JJ
cord-257662-viy65y72	19	25	and	and	CC
cord-257662-viy65y72	19	26	self	self	NN
cord-257662-viy65y72	19	27	antigens	antigen	NNS
cord-257662-viy65y72	19	28	following	follow	VBG
cord-257662-viy65y72	19	29	infection	infection	NN
cord-257662-viy65y72	19	30	or	or	CC
cord-257662-viy65y72	19	31	injury	injury	NN
cord-257662-viy65y72	19	32	,	,	,
cord-257662-viy65y72	19	33	pathogen	pathogen	NN
cord-257662-viy65y72	19	34	clearance	clearance	NN
cord-257662-viy65y72	19	35	,	,	,
cord-257662-viy65y72	19	36	and	and	CC
cord-257662-viy65y72	19	37	resolution	resolution	NN
cord-257662-viy65y72	19	38	of	of	IN
cord-257662-viy65y72	19	39	inflammation	inflammation	NN
cord-257662-viy65y72	19	40	and	and	CC
cord-257662-viy65y72	19	41	wound	wound	VB
cord-257662-viy65y72	19	42	healing	healing	NN
cord-257662-viy65y72	19	43	.	.	.
cord-257662-viy65y72	20	1	Depending	depend	VBG
cord-257662-viy65y72	20	2	on	on	IN
cord-257662-viy65y72	20	3	the	the	DT
cord-257662-viy65y72	20	4	microenvironment	microenvironment	NN
cord-257662-viy65y72	20	5	,	,	,
cord-257662-viy65y72	20	6	macrophages	macrophage	NNS
cord-257662-viy65y72	20	7	can	can	MD
cord-257662-viy65y72	20	8	be	be	VB
cord-257662-viy65y72	20	9	programed	program	VBN
cord-257662-viy65y72	20	10	to	to	TO
cord-257662-viy65y72	20	11	adopt	adopt	VB
cord-257662-viy65y72	20	12	a	a	DT
cord-257662-viy65y72	20	13	variety	variety	NN
cord-257662-viy65y72	20	14	of	of	IN
cord-257662-viy65y72	20	15	proinflammatory	proinflammatory	JJ
cord-257662-viy65y72	20	16	,	,	,
cord-257662-viy65y72	20	17	regulatory	regulatory	JJ
cord-257662-viy65y72	20	18	,	,	,
cord-257662-viy65y72	20	19	resolving	resolve	VBG
cord-257662-viy65y72	20	20	,	,	,
cord-257662-viy65y72	20	21	and	and	CC
cord-257662-viy65y72	20	22	immunosuppressive	immunosuppressive	JJ
cord-257662-viy65y72	20	23	activation	activation	NN
cord-257662-viy65y72	20	24	phenotypes	phenotype	NNS
cord-257662-viy65y72	20	25	,	,	,
cord-257662-viy65y72	20	26	particularly	particularly	RB
cord-257662-viy65y72	20	27	in	in	IN
cord-257662-viy65y72	20	28	vivo	vivo	NNP
cord-257662-viy65y72	20	29	.	.	.
cord-257662-viy65y72	21	1	These	these	DT
cord-257662-viy65y72	21	2	activation	activation	NN
cord-257662-viy65y72	21	3	states	state	NNS
cord-257662-viy65y72	21	4	exist	exist	VBP
cord-257662-viy65y72	21	5	as	as	IN
cord-257662-viy65y72	21	6	a	a	DT
cord-257662-viy65y72	21	7	complex	complex	JJ
cord-257662-viy65y72	21	8	continuum	continuum	NN
cord-257662-viy65y72	21	9	of	of	IN
cord-257662-viy65y72	21	10	overlapping	overlap	VBG
cord-257662-viy65y72	21	11	phenotypes	phenotype	NNS
cord-257662-viy65y72	21	12	;	;	:
cord-257662-viy65y72	21	13	however	however	RB
cord-257662-viy65y72	21	14	,	,	,
cord-257662-viy65y72	21	15	macrophage	macrophage	NN
cord-257662-viy65y72	21	16	subsets	subset	NNS
cord-257662-viy65y72	21	17	with	with	IN
cord-257662-viy65y72	21	18	distinct	distinct	JJ
cord-257662-viy65y72	21	19	functions	function	NNS
cord-257662-viy65y72	21	20	have	have	VBP
cord-257662-viy65y72	21	21	been	be	VBN
cord-257662-viy65y72	21	22	defined	define	VBN
cord-257662-viy65y72	21	23	(	(	-LRB-
cord-257662-viy65y72	21	24	1	1	CD
cord-257662-viy65y72	21	25	)	)	-RRB-
cord-257662-viy65y72	21	26	.	.	.
cord-257662-viy65y72	22	1	Macrophages	macrophage	NNS
cord-257662-viy65y72	22	2	are	be	VBP
cord-257662-viy65y72	22	3	considered	consider	VBN
cord-257662-viy65y72	22	4	M1-polarized	m1-polarize	VBN
cord-257662-viy65y72	22	5	when	when	WRB
cord-257662-viy65y72	22	6	stimulated	stimulate	VBN
cord-257662-viy65y72	22	7	by	by	IN
cord-257662-viy65y72	22	8	IFN	IFN	NNP
cord-257662-viy65y72	22	9	-	-	HYPH
cord-257662-viy65y72	22	10	γ	γ	NNP
cord-257662-viy65y72	22	11	or	or	CC
cord-257662-viy65y72	22	12	Toll	Toll	NNP
cord-257662-viy65y72	22	13	-	-	HYPH
cord-257662-viy65y72	22	14	like	like	JJ
cord-257662-viy65y72	22	15	receptor	receptor	NN
cord-257662-viy65y72	22	16	(	(	-LRB-
cord-257662-viy65y72	22	17	TLR	TLR	NNP
cord-257662-viy65y72	22	18	)	)	-RRB-
cord-257662-viy65y72	22	19	ligands	ligand	NNS
cord-257662-viy65y72	22	20	,	,	,
cord-257662-viy65y72	22	21	such	such	JJ
cord-257662-viy65y72	22	22	as	as	IN
cord-257662-viy65y72	22	23	lipopolysaccharide	lipopolysaccharide	NN
cord-257662-viy65y72	22	24	(	(	-LRB-
cord-257662-viy65y72	22	25	LPS	LPS	NNP
cord-257662-viy65y72	22	26	)	)	-RRB-
cord-257662-viy65y72	22	27	,	,	,
cord-257662-viy65y72	22	28	to	to	TO
cord-257662-viy65y72	22	29	express	express	VB
cord-257662-viy65y72	22	30	inducible	inducible	JJ
cord-257662-viy65y72	22	31	nitric	nitric	NN
cord-257662-viy65y72	22	32	oxide	oxide	NN
cord-257662-viy65y72	22	33	synthase	synthase	NN
cord-257662-viy65y72	22	34	(	(	-LRB-
cord-257662-viy65y72	22	35	iNOS	iNOS	''
cord-257662-viy65y72	22	36	;	;	:
cord-257662-viy65y72	22	37	Nos2	Nos2	NNP
cord-257662-viy65y72	22	38	)	)	-RRB-
cord-257662-viy65y72	22	39	and	and	CC
cord-257662-viy65y72	22	40	produce	produce	VBP
cord-257662-viy65y72	22	41	nitric	nitric	NN
cord-257662-viy65y72	22	42	oxide	oxide	NN
cord-257662-viy65y72	22	43	(	(	-LRB-
cord-257662-viy65y72	22	44	NO	no	RB
cord-257662-viy65y72	22	45	)	)	-RRB-
cord-257662-viy65y72	22	46	.	.	.
cord-257662-viy65y72	23	1	NOS	NOS	NNP
cord-257662-viy65y72	23	2	enzymes	enzyme	NNS
cord-257662-viy65y72	23	3	metabolize	metabolize	VBP
cord-257662-viy65y72	23	4	l	l	NN
cord-257662-viy65y72	23	5	-	-	HYPH
cord-257662-viy65y72	23	6	arginine	arginine	NN
cord-257662-viy65y72	23	7	to	to	IN
cord-257662-viy65y72	23	8	citrulline	citrulline	NN
cord-257662-viy65y72	23	9	and	and	CC
cord-257662-viy65y72	24	1	NO	no	UH
cord-257662-viy65y72	24	2	.	.	.
cord-257662-viy65y72	25	1	NO	no	UH
cord-257662-viy65y72	25	2	is	be	VBZ
cord-257662-viy65y72	25	3	a	a	DT
cord-257662-viy65y72	25	4	short	short	RB
cord-257662-viy65y72	25	5	-	-	HYPH
cord-257662-viy65y72	25	6	lived	live	VBN
cord-257662-viy65y72	25	7	gaseous	gaseous	JJ
cord-257662-viy65y72	25	8	messenger	messenger	NN
cord-257662-viy65y72	25	9	with	with	IN
cord-257662-viy65y72	25	10	physiological	physiological	JJ
cord-257662-viy65y72	25	11	and	and	CC
cord-257662-viy65y72	25	12	pathological	pathological	JJ
cord-257662-viy65y72	25	13	effects	effect	NNS
cord-257662-viy65y72	25	14	.	.	.
cord-257662-viy65y72	26	1	Nanomolar	Nanomolar	NNP
cord-257662-viy65y72	26	2	concentrations	concentration	NNS
cord-257662-viy65y72	26	3	of	of	IN
cord-257662-viy65y72	26	4	NO	no	NN
cord-257662-viy65y72	26	5	,	,	,
cord-257662-viy65y72	26	6	generated	generate	VBN
cord-257662-viy65y72	26	7	by	by	IN
cord-257662-viy65y72	26	8	endothelial	endothelial	JJ
cord-257662-viy65y72	26	9	NOS	NOS	NNP
cord-257662-viy65y72	26	10	and	and	CC
cord-257662-viy65y72	26	11	neuronal	neuronal	JJ
cord-257662-viy65y72	26	12	NOS	NOS	NNP
cord-257662-viy65y72	26	13	,	,	,
cord-257662-viy65y72	26	14	are	be	VBP
cord-257662-viy65y72	26	15	important	important	JJ
cord-257662-viy65y72	26	16	for	for	IN
cord-257662-viy65y72	26	17	maintaining	maintain	VBG
cord-257662-viy65y72	26	18	homeostasis	homeostasis	NN
cord-257662-viy65y72	26	19	,	,	,
cord-257662-viy65y72	26	20	regulating	regulate	VBG
cord-257662-viy65y72	26	21	vasodilation	vasodilation	NN
cord-257662-viy65y72	26	22	,	,	,
cord-257662-viy65y72	26	23	and	and	CC
cord-257662-viy65y72	26	24	for	for	IN
cord-257662-viy65y72	26	25	the	the	DT
cord-257662-viy65y72	26	26	aggregation	aggregation	NN
cord-257662-viy65y72	26	27	,	,	,
cord-257662-viy65y72	26	28	recruitment	recruitment	NN
cord-257662-viy65y72	26	29	,	,	,
cord-257662-viy65y72	26	30	and	and	CC
cord-257662-viy65y72	26	31	adhesion	adhesion	NN
cord-257662-viy65y72	26	32	of	of	IN
cord-257662-viy65y72	26	33	platelets	platelet	NNS
cord-257662-viy65y72	26	34	to	to	IN
cord-257662-viy65y72	26	35	the	the	DT
cord-257662-viy65y72	26	36	vascular	vascular	JJ
cord-257662-viy65y72	26	37	endothelium	endothelium	NN
cord-257662-viy65y72	26	38	.	.	.
cord-257662-viy65y72	27	1	iNOS	iNOS	NNP
cord-257662-viy65y72	27	2	generates	generate	VBZ
cord-257662-viy65y72	27	3	micromolar	micromolar	JJ
cord-257662-viy65y72	27	4	levels	level	NNS
cord-257662-viy65y72	27	5	of	of	IN
cord-257662-viy65y72	27	6	NO	no	DT
cord-257662-viy65y72	27	7	that	that	WDT
cord-257662-viy65y72	27	8	modulates	modulate	VBZ
cord-257662-viy65y72	27	9	various	various	JJ
cord-257662-viy65y72	27	10	pathophysiological	pathophysiological	JJ
cord-257662-viy65y72	27	11	processes	process	NNS
cord-257662-viy65y72	27	12	and	and	CC
cord-257662-viy65y72	27	13	is	be	VBZ
cord-257662-viy65y72	27	14	important	important	JJ
cord-257662-viy65y72	27	15	for	for	IN
cord-257662-viy65y72	27	16	killing	kill	VBG
cord-257662-viy65y72	27	17	intracellular	intracellular	JJ
cord-257662-viy65y72	27	18	pathogens	pathogen	NNS
cord-257662-viy65y72	27	19	(	(	-LRB-
cord-257662-viy65y72	27	20	2	2	CD
cord-257662-viy65y72	27	21	)	)	-RRB-
cord-257662-viy65y72	27	22	.	.	.
cord-257662-viy65y72	28	1	In	in	IN
cord-257662-viy65y72	28	2	contrast	contrast	NN
cord-257662-viy65y72	28	3	,	,	,
cord-257662-viy65y72	28	4	M2-polarized	m2-polarize	VBN
cord-257662-viy65y72	28	5	macrophages	macrophage	NNS
cord-257662-viy65y72	28	6	result	result	VBP
cord-257662-viy65y72	28	7	following	follow	VBG
cord-257662-viy65y72	28	8	stimulation	stimulation	NN
cord-257662-viy65y72	28	9	of	of	IN
cord-257662-viy65y72	28	10	cells	cell	NNS
cord-257662-viy65y72	28	11	with	with	IN
cord-257662-viy65y72	28	12	a	a	DT
cord-257662-viy65y72	28	13	variety	variety	NN
cord-257662-viy65y72	28	14	of	of	IN
cord-257662-viy65y72	28	15	stimuli	stimulus	NNS
cord-257662-viy65y72	28	16	,	,	,
cord-257662-viy65y72	28	17	including	include	VBG
cord-257662-viy65y72	28	18	type	type	NN
cord-257662-viy65y72	28	19	2	2	CD
cord-257662-viy65y72	28	20	cytokines	cytokine	NNS
cord-257662-viy65y72	28	21	such	such	JJ
cord-257662-viy65y72	28	22	as	as	IN
cord-257662-viy65y72	28	23	interleukin	interleukin	NN
cord-257662-viy65y72	28	24	(	(	-LRB-
cord-257662-viy65y72	28	25	IL)-4	IL)-4	NNP
cord-257662-viy65y72	28	26	or	or	CC
cord-257662-viy65y72	28	27	IL-13	IL-13	NNP
cord-257662-viy65y72	28	28	.	.	.
cord-257662-viy65y72	29	1	M2-polarized	m2-polarize	VBN
cord-257662-viy65y72	29	2	macrophages	macrophage	NNS
cord-257662-viy65y72	29	3	express	express	VBP
cord-257662-viy65y72	29	4	a	a	DT
cord-257662-viy65y72	29	5	distinct	distinct	JJ
cord-257662-viy65y72	29	6	l	l	NN
cord-257662-viy65y72	29	7	-	-	HYPH
cord-257662-viy65y72	29	8	arginine	arginine	NN
cord-257662-viy65y72	29	9	-	-	HYPH
cord-257662-viy65y72	29	10	metabolizing	metabolize	VBG
cord-257662-viy65y72	29	11	enzyme	enzyme	NN
cord-257662-viy65y72	29	12	,	,	,
cord-257662-viy65y72	29	13	arginase	arginase	NNP
cord-257662-viy65y72	29	14	1	1	CD
cord-257662-viy65y72	29	15	(	(	-LRB-
cord-257662-viy65y72	29	16	Arg1	Arg1	NNP
cord-257662-viy65y72	29	17	)	)	-RRB-
cord-257662-viy65y72	29	18	,	,	,
cord-257662-viy65y72	29	19	which	which	WDT
cord-257662-viy65y72	29	20	hydrolyzes	hydrolyze	VBZ
cord-257662-viy65y72	29	21	l	l	NN
cord-257662-viy65y72	29	22	-	-	HYPH
cord-257662-viy65y72	29	23	arginine	arginine	NN
cord-257662-viy65y72	29	24	to	to	IN
cord-257662-viy65y72	29	25	l	l	NN
cord-257662-viy65y72	29	26	-	-	HYPH
cord-257662-viy65y72	29	27	ornithine	ornithine	NN
cord-257662-viy65y72	29	28	and	and	CC
cord-257662-viy65y72	29	29	urea	urea	NN
cord-257662-viy65y72	29	30	.	.	.
cord-257662-viy65y72	30	1	l	l	LS
cord-257662-viy65y72	30	2	-	-	HYPH
cord-257662-viy65y72	30	3	Ornithine	Ornithine	NNP
cord-257662-viy65y72	30	4	can	can	MD
cord-257662-viy65y72	30	5	be	be	VB
cord-257662-viy65y72	30	6	further	further	RB
cord-257662-viy65y72	30	7	metabolized	metabolize	VBN
cord-257662-viy65y72	30	8	to	to	IN
cord-257662-viy65y72	30	9	polyamines	polyamine	NNS
cord-257662-viy65y72	30	10	,	,	,
cord-257662-viy65y72	30	11	which	which	WDT
cord-257662-viy65y72	30	12	participate	participate	VBP
cord-257662-viy65y72	30	13	in	in	IN
cord-257662-viy65y72	30	14	a	a	DT
cord-257662-viy65y72	30	15	variety	variety	NN
cord-257662-viy65y72	30	16	of	of	IN
cord-257662-viy65y72	30	17	fundamental	fundamental	JJ
cord-257662-viy65y72	30	18	cellular	cellular	JJ
cord-257662-viy65y72	30	19	functions	function	NNS
cord-257662-viy65y72	30	20	(	(	-LRB-
cord-257662-viy65y72	30	21	e.g.	e.g.	RB
cord-257662-viy65y72	30	22	,	,	,
cord-257662-viy65y72	30	23	proliferation	proliferation	NN
cord-257662-viy65y72	30	24	,	,	,
cord-257662-viy65y72	30	25	cell	cell	NN
cord-257662-viy65y72	30	26	membrane	membrane	NN
cord-257662-viy65y72	30	27	transport	transport	NN
cord-257662-viy65y72	30	28	)	)	-RRB-
cord-257662-viy65y72	30	29	,	,	,
cord-257662-viy65y72	30	30	and	and	CC
cord-257662-viy65y72	30	31	l	l	NN
cord-257662-viy65y72	30	32	-	-	HYPH
cord-257662-viy65y72	30	33	proline	proline	NN
cord-257662-viy65y72	30	34	,	,	,
cord-257662-viy65y72	30	35	which	which	WDT
cord-257662-viy65y72	30	36	is	be	VBZ
cord-257662-viy65y72	30	37	an	an	DT
cord-257662-viy65y72	30	38	essential	essential	JJ
cord-257662-viy65y72	30	39	component	component	NN
cord-257662-viy65y72	30	40	of	of	IN
cord-257662-viy65y72	30	41	collagen	collagen	NN
cord-257662-viy65y72	30	42	.	.	.
cord-257662-viy65y72	31	1	In	in	IN
cord-257662-viy65y72	31	2	addition	addition	NN
cord-257662-viy65y72	31	3	to	to	IN
cord-257662-viy65y72	31	4	playing	play	VBG
cord-257662-viy65y72	31	5	important	important	JJ
cord-257662-viy65y72	31	6	roles	role	NNS
cord-257662-viy65y72	31	7	in	in	IN
cord-257662-viy65y72	31	8	defense	defense	NN
cord-257662-viy65y72	31	9	against	against	IN
cord-257662-viy65y72	31	10	extracellular	extracellular	JJ
cord-257662-viy65y72	31	11	parasites	parasite	NNS
cord-257662-viy65y72	31	12	and	and	CC
cord-257662-viy65y72	31	13	tissue	tissue	NN
cord-257662-viy65y72	31	14	repair	repair	NN
cord-257662-viy65y72	31	15	,	,	,
cord-257662-viy65y72	31	16	Arg1	arg1	JJ
cord-257662-viy65y72	31	17	expression	expression	NN
cord-257662-viy65y72	31	18	and	and	CC
cord-257662-viy65y72	31	19	activity	activity	NN
cord-257662-viy65y72	31	20	in	in	IN
cord-257662-viy65y72	31	21	myeloid	myeloid	JJ
cord-257662-viy65y72	31	22	cells	cell	NNS
cord-257662-viy65y72	31	23	have	have	VBP
cord-257662-viy65y72	31	24	emerged	emerge	VBN
cord-257662-viy65y72	31	25	as	as	IN
cord-257662-viy65y72	31	26	a	a	DT
cord-257662-viy65y72	31	27	major	major	JJ
cord-257662-viy65y72	31	28	regulator	regulator	NN
cord-257662-viy65y72	31	29	of	of	IN
cord-257662-viy65y72	31	30	innate	innate	JJ
cord-257662-viy65y72	31	31	and	and	CC
cord-257662-viy65y72	31	32	adaptive	adaptive	JJ
cord-257662-viy65y72	31	33	immune	immune	JJ
cord-257662-viy65y72	31	34	responses	response	NNS
cord-257662-viy65y72	31	35	(	(	-LRB-
cord-257662-viy65y72	31	36	3	3	CD
cord-257662-viy65y72	31	37	)	)	-RRB-
cord-257662-viy65y72	31	38	.	.	.
cord-257662-viy65y72	32	1	Other	other	JJ
cord-257662-viy65y72	32	2	M2-like	M2-like	NNS
cord-257662-viy65y72	32	3	suppressive	suppressive	JJ
cord-257662-viy65y72	32	4	or	or	CC
cord-257662-viy65y72	32	5	anti	anti	JJ
cord-257662-viy65y72	32	6	-	-	JJ
cord-257662-viy65y72	32	7	inflammatory	inflammatory	JJ
cord-257662-viy65y72	32	8	macrophages	macrophage	NNS
cord-257662-viy65y72	32	9	include	include	VBP
cord-257662-viy65y72	32	10	myeloid	myeloid	NN
cord-257662-viy65y72	32	11	-	-	HYPH
cord-257662-viy65y72	32	12	derived	derive	VBN
cord-257662-viy65y72	32	13	suppressor	suppressor	NN
cord-257662-viy65y72	32	14	cells	cell	NNS
cord-257662-viy65y72	32	15	(	(	-LRB-
cord-257662-viy65y72	32	16	MDSCs	mdsc	NNS
cord-257662-viy65y72	32	17	)	)	-RRB-
cord-257662-viy65y72	32	18	and	and	CC
cord-257662-viy65y72	32	19	tumor	tumor	NN
cord-257662-viy65y72	32	20	-	-	HYPH
cord-257662-viy65y72	32	21	associated	associate	VBN
cord-257662-viy65y72	32	22	macrophages	macrophage	NNS
cord-257662-viy65y72	32	23	(	(	-LRB-
cord-257662-viy65y72	32	24	TAMs	tam	NNS
cord-257662-viy65y72	32	25	)	)	-RRB-
cord-257662-viy65y72	32	26	.	.	.
cord-257662-viy65y72	33	1	MDSCs	mdsc	NNS
cord-257662-viy65y72	33	2	are	be	VBP
cord-257662-viy65y72	33	3	considered	consider	VBN
cord-257662-viy65y72	33	4	to	to	TO
cord-257662-viy65y72	33	5	be	be	VB
cord-257662-viy65y72	33	6	an	an	DT
cord-257662-viy65y72	33	7	immature	immature	JJ
cord-257662-viy65y72	33	8	population	population	NN
cord-257662-viy65y72	33	9	of	of	IN
cord-257662-viy65y72	33	10	myeloid	myeloid	NN
cord-257662-viy65y72	33	11	cells	cell	NNS
cord-257662-viy65y72	33	12	,	,	,
cord-257662-viy65y72	33	13	including	include	VBG
cord-257662-viy65y72	33	14	both	both	DT
cord-257662-viy65y72	33	15	monocyte	monocyte	NNP
cord-257662-viy65y72	33	16	-	-	HYPH
cord-257662-viy65y72	33	17	like	like	JJ
cord-257662-viy65y72	33	18	(	(	-LRB-
cord-257662-viy65y72	33	19	GR-1	GR-1	NNP
cord-257662-viy65y72	33	20	/	/	SYM
cord-257662-viy65y72	33	21	Ly-6C	Ly-6C	NNP
cord-257662-viy65y72	33	22	+	+	CC
cord-257662-viy65y72	33	23	)	)	-RRB-
cord-257662-viy65y72	33	24	and	and	CC
cord-257662-viy65y72	33	25	neutrophil	neutrophil	NN
cord-257662-viy65y72	33	26	-	-	HYPH
cord-257662-viy65y72	33	27	like	like	JJ
cord-257662-viy65y72	33	28	(	(	-LRB-
cord-257662-viy65y72	33	29	GR-1	GR-1	NNP
cord-257662-viy65y72	33	30	/	/	SYM
cord-257662-viy65y72	33	31	Ly-6	Ly-6	NNP
cord-257662-viy65y72	33	32	G	G	NNP
cord-257662-viy65y72	33	33	+	+	SYM
cord-257662-viy65y72	33	34	)	)	-RRB-
cord-257662-viy65y72	33	35	populations	population	NNS
cord-257662-viy65y72	33	36	,	,	,
cord-257662-viy65y72	33	37	associated	associate	VBN
cord-257662-viy65y72	33	38	with	with	IN
cord-257662-viy65y72	33	39	tumors	tumor	NNS
cord-257662-viy65y72	33	40	or	or	CC
cord-257662-viy65y72	33	41	infections	infection	NNS
cord-257662-viy65y72	33	42	that	that	WDT
cord-257662-viy65y72	33	43	suppress	suppress	VBP
cord-257662-viy65y72	33	44	proinflammatory	proinflammatory	JJ
cord-257662-viy65y72	33	45	responses	response	NNS
cord-257662-viy65y72	33	46	(	(	-LRB-
cord-257662-viy65y72	33	47	4	4	CD
cord-257662-viy65y72	33	48	,	,	,
cord-257662-viy65y72	33	49	5	5	CD
cord-257662-viy65y72	33	50	)	)	-RRB-
cord-257662-viy65y72	33	51	.	.	.
cord-257662-viy65y72	34	1	Depending	depend	VBG
cord-257662-viy65y72	34	2	on	on	IN
cord-257662-viy65y72	34	3	the	the	DT
cord-257662-viy65y72	34	4	context	context	NN
cord-257662-viy65y72	34	5	,	,	,
cord-257662-viy65y72	34	6	MDSCs	mdsc	NNS
cord-257662-viy65y72	34	7	have	have	VBP
cord-257662-viy65y72	34	8	been	be	VBN
cord-257662-viy65y72	34	9	shown	show	VBN
cord-257662-viy65y72	34	10	to	to	TO
cord-257662-viy65y72	34	11	mediate	mediate	VB
cord-257662-viy65y72	34	12	their	-PRON-	PRP$
cord-257662-viy65y72	34	13	suppressive	suppressive	JJ
cord-257662-viy65y72	34	14	activity	activity	NN
cord-257662-viy65y72	34	15	via	via	IN
cord-257662-viy65y72	34	16	NO	no	JJ
cord-257662-viy65y72	34	17	-	-	HYPH
cord-257662-viy65y72	34	18	and	and	CC
cord-257662-viy65y72	34	19	/	/	SYM
cord-257662-viy65y72	34	20	or	or	CC
cord-257662-viy65y72	34	21	Arg1-dependent	arg1-dependent	NN
cord-257662-viy65y72	34	22	mechanisms	mechanism	NNS
cord-257662-viy65y72	34	23	.	.	.
cord-257662-viy65y72	35	1	Importantly	importantly	RB
cord-257662-viy65y72	35	2	,	,	,
cord-257662-viy65y72	35	3	macrophages	macrophage	NNS
cord-257662-viy65y72	35	4	are	be	VBP
cord-257662-viy65y72	35	5	not	not	RB
cord-257662-viy65y72	35	6	permanently	permanently	RB
cord-257662-viy65y72	35	7	programed	program	VBN
cord-257662-viy65y72	35	8	,	,	,
cord-257662-viy65y72	35	9	but	but	CC
cord-257662-viy65y72	35	10	are	be	VBP
cord-257662-viy65y72	35	11	considered	consider	VBN
cord-257662-viy65y72	35	12	"	"	``
cord-257662-viy65y72	35	13	plastic	plastic	JJ
cord-257662-viy65y72	36	1	"	"	``
cord-257662-viy65y72	36	2	-that	-that	NN
cord-257662-viy65y72	36	3	is	be	VBZ
cord-257662-viy65y72	36	4	,	,	,
cord-257662-viy65y72	36	5	macrophages	macrophage	NNS
cord-257662-viy65y72	36	6	have	have	VBP
cord-257662-viy65y72	36	7	been	be	VBN
cord-257662-viy65y72	36	8	shown	show	VBN
cord-257662-viy65y72	36	9	to	to	TO
cord-257662-viy65y72	36	10	change	change	VB
cord-257662-viy65y72	36	11	activation	activation	NN
cord-257662-viy65y72	36	12	phenotypes	phenotype	NNS
cord-257662-viy65y72	36	13	depending	depend	VBG
cord-257662-viy65y72	36	14	on	on	IN
cord-257662-viy65y72	36	15	the	the	DT
cord-257662-viy65y72	36	16	local	local	JJ
cord-257662-viy65y72	36	17	environment	environment	NN
cord-257662-viy65y72	36	18	.	.	.
cord-257662-viy65y72	37	1	Although	although	IN
cord-257662-viy65y72	37	2	the	the	DT
cord-257662-viy65y72	37	3	M1	M1	NNP
cord-257662-viy65y72	37	4	/	/	SYM
cord-257662-viy65y72	37	5	iNOS	iNOS	NNP
cord-257662-viy65y72	37	6	and	and	CC
cord-257662-viy65y72	37	7	M2	M2	NNP
cord-257662-viy65y72	37	8	/	/	SYM
cord-257662-viy65y72	37	9	Arg1	Arg1	NNP
cord-257662-viy65y72	37	10	division	division	NN
cord-257662-viy65y72	37	11	is	be	VBZ
cord-257662-viy65y72	37	12	generally	generally	RB
cord-257662-viy65y72	37	13	appropriate	appropriate	JJ
cord-257662-viy65y72	37	14	,	,	,
cord-257662-viy65y72	37	15	Arg1	Arg1	NNP
cord-257662-viy65y72	37	16	can	can	MD
cord-257662-viy65y72	37	17	be	be	VB
cord-257662-viy65y72	37	18	induced	induce	VBN
cord-257662-viy65y72	37	19	in	in	IN
cord-257662-viy65y72	37	20	M1-like	m1-like	IN
cord-257662-viy65y72	37	21	macrophages	macrophage	NNS
cord-257662-viy65y72	37	22	under	under	IN
cord-257662-viy65y72	37	23	certain	certain	JJ
cord-257662-viy65y72	37	24	conditions	condition	NNS
cord-257662-viy65y72	37	25	.	.	.
cord-257662-viy65y72	38	1	Thus	thus	RB
cord-257662-viy65y72	38	2	,	,	,
cord-257662-viy65y72	38	3	due	due	IN
cord-257662-viy65y72	38	4	to	to	IN
cord-257662-viy65y72	38	5	the	the	DT
cord-257662-viy65y72	38	6	spectrum	spectrum	NN
cord-257662-viy65y72	38	7	of	of	IN
cord-257662-viy65y72	38	8	activation	activation	NN
cord-257662-viy65y72	38	9	states	state	NNS
cord-257662-viy65y72	38	10	for	for	IN
cord-257662-viy65y72	38	11	macrophages	macrophage	NNS
cord-257662-viy65y72	38	12	,	,	,
cord-257662-viy65y72	38	13	a	a	DT
cord-257662-viy65y72	38	14	framework	framework	NN
cord-257662-viy65y72	38	15	for	for	IN
cord-257662-viy65y72	38	16	macrophage	macrophage	NN
cord-257662-viy65y72	38	17	-	-	HYPH
cord-257662-viy65y72	38	18	activation	activation	NN
cord-257662-viy65y72	38	19	nomenclature	nomenclature	NN
cord-257662-viy65y72	38	20	was	be	VBD
cord-257662-viy65y72	38	21	recently	recently	RB
cord-257662-viy65y72	38	22	suggested	suggest	VBN
cord-257662-viy65y72	38	23	(	(	-LRB-
cord-257662-viy65y72	38	24	6	6	CD
cord-257662-viy65y72	38	25	)	)	-RRB-
cord-257662-viy65y72	38	26	.	.	.
cord-257662-viy65y72	39	1	In	in	IN
cord-257662-viy65y72	39	2	an	an	DT
cord-257662-viy65y72	39	3	attempt	attempt	NN
cord-257662-viy65y72	39	4	to	to	TO
cord-257662-viy65y72	39	5	avoid	avoid	VB
cord-257662-viy65y72	39	6	confusion	confusion	NN
cord-257662-viy65y72	39	7	in	in	IN
cord-257662-viy65y72	39	8	this	this	DT
cord-257662-viy65y72	39	9	review	review	NN
cord-257662-viy65y72	39	10	,	,	,
cord-257662-viy65y72	39	11	we	-PRON-	PRP
cord-257662-viy65y72	39	12	focused	focus	VBD
cord-257662-viy65y72	39	13	on	on	IN
cord-257662-viy65y72	39	14	the	the	DT
cord-257662-viy65y72	39	15	specific	specific	JJ
cord-257662-viy65y72	39	16	effects	effect	NNS
cord-257662-viy65y72	39	17	of	of	IN
cord-257662-viy65y72	39	18	the	the	DT
cord-257662-viy65y72	39	19	l	l	NN
cord-257662-viy65y72	39	20	-	-	HYPH
cord-257662-viy65y72	39	21	arginine	arginine	NN
cord-257662-viy65y72	39	22	metabolizing	metabolize	VBG
cord-257662-viy65y72	39	23	enzymes	enzyme	NNS
cord-257662-viy65y72	39	24	iNOS	inos	RB
cord-257662-viy65y72	40	1	or	or	CC
cord-257662-viy65y72	40	2	Arg1	Arg1	NNP
cord-257662-viy65y72	40	3	on	on	IN
cord-257662-viy65y72	40	4	the	the	DT
cord-257662-viy65y72	40	5	pathogenesis	pathogenesis	NN
cord-257662-viy65y72	40	6	of	of	IN
cord-257662-viy65y72	40	7	viral	viral	JJ
cord-257662-viy65y72	40	8	infections	infection	NNS
cord-257662-viy65y72	40	9	,	,	,
cord-257662-viy65y72	40	10	noting	note	VBG
cord-257662-viy65y72	40	11	other	other	JJ
cord-257662-viy65y72	40	12	activation	activation	NN
cord-257662-viy65y72	40	13	markers	marker	NNS
cord-257662-viy65y72	40	14	where	where	WRB
cord-257662-viy65y72	40	15	appropriate	appropriate	JJ
cord-257662-viy65y72	40	16	.	.	.
cord-257662-viy65y72	41	1	Increasing	increase	VBG
cord-257662-viy65y72	41	2	evidence	evidence	NN
cord-257662-viy65y72	41	3	suggests	suggest	VBZ
cord-257662-viy65y72	41	4	that	that	IN
cord-257662-viy65y72	41	5	myeloid	myeloid	JJ
cord-257662-viy65y72	41	6	cell	cell	NN
cord-257662-viy65y72	41	7	programing	programing	NN
cord-257662-viy65y72	41	8	,	,	,
cord-257662-viy65y72	41	9	iNOS	inos	CD
cord-257662-viy65y72	41	10	,	,	,
cord-257662-viy65y72	41	11	and	and	CC
cord-257662-viy65y72	41	12	Arg1	Arg1	NNP
cord-257662-viy65y72	41	13	contribute	contribute	VB
cord-257662-viy65y72	41	14	to	to	IN
cord-257662-viy65y72	41	15	the	the	DT
cord-257662-viy65y72	41	16	pathogenesis	pathogenesis	NN
cord-257662-viy65y72	41	17	of	of	IN
cord-257662-viy65y72	41	18	numerous	numerous	JJ
cord-257662-viy65y72	41	19	virus	virus	NN
cord-257662-viy65y72	41	20	infections	infection	NNS
cord-257662-viy65y72	41	21	,	,	,
cord-257662-viy65y72	41	22	suggesting	suggest	VBG
cord-257662-viy65y72	41	23	that	that	IN
cord-257662-viy65y72	41	24	therapies	therapy	NNS
cord-257662-viy65y72	41	25	that	that	WDT
cord-257662-viy65y72	41	26	target	target	VBP
cord-257662-viy65y72	41	27	these	these	DT
cord-257662-viy65y72	41	28	cells	cell	NNS
cord-257662-viy65y72	41	29	and	and	CC
cord-257662-viy65y72	41	30	pathways	pathway	NNS
cord-257662-viy65y72	41	31	may	may	MD
cord-257662-viy65y72	41	32	be	be	VB
cord-257662-viy65y72	41	33	beneficial	beneficial	JJ
cord-257662-viy65y72	41	34	for	for	IN
cord-257662-viy65y72	41	35	the	the	DT
cord-257662-viy65y72	41	36	treatment	treatment	NN
cord-257662-viy65y72	41	37	of	of	IN
cord-257662-viy65y72	41	38	some	some	DT
cord-257662-viy65y72	41	39	virus	virus	NN
cord-257662-viy65y72	41	40	diseases	disease	NNS
cord-257662-viy65y72	41	41	.	.	.
cord-257662-viy65y72	42	1	In	in	IN
cord-257662-viy65y72	42	2	this	this	DT
cord-257662-viy65y72	42	3	review	review	NN
cord-257662-viy65y72	42	4	,	,	,
cord-257662-viy65y72	42	5	we	-PRON-	PRP
cord-257662-viy65y72	42	6	highlight	highlight	VBP
cord-257662-viy65y72	42	7	recent	recent	JJ
cord-257662-viy65y72	42	8	studies	study	NNS
cord-257662-viy65y72	42	9	of	of	IN
cord-257662-viy65y72	42	10	viral	viral	JJ
cord-257662-viy65y72	42	11	infections	infection	NNS
cord-257662-viy65y72	42	12	where	where	WRB
cord-257662-viy65y72	42	13	myeloid	myeloid	JJ
cord-257662-viy65y72	42	14	cell	cell	NN
cord-257662-viy65y72	42	15	polarization	polarization	NN
cord-257662-viy65y72	42	16	-resulting	-resulte	VBG
cord-257662-viy65y72	42	17	in	in	IN
cord-257662-viy65y72	42	18	expression	expression	NN
cord-257662-viy65y72	42	19	of	of	IN
cord-257662-viy65y72	42	20	iNOS	inos	JJ
cord-257662-viy65y72	42	21	or	or	CC
cord-257662-viy65y72	42	22	Arg1	Arg1	NNP
cord-257662-viy65y72	42	23	-contribute	-contribute	VBG
cord-257662-viy65y72	42	24	to	to	IN
cord-257662-viy65y72	42	25	viral	viral	JJ
cord-257662-viy65y72	42	26	control	control	NN
cord-257662-viy65y72	42	27	or	or	CC
cord-257662-viy65y72	42	28	the	the	DT
cord-257662-viy65y72	42	29	development	development	NN
cord-257662-viy65y72	42	30	of	of	IN
cord-257662-viy65y72	42	31	chronic	chronic	JJ
cord-257662-viy65y72	42	32	virus	virus	NN
cord-257662-viy65y72	42	33	infection	infection	NN
cord-257662-viy65y72	42	34	and	and	CC
cord-257662-viy65y72	42	35	mediate	mediate	VB
cord-257662-viy65y72	42	36	the	the	DT
cord-257662-viy65y72	42	37	resolution	resolution	NN
cord-257662-viy65y72	42	38	of	of	IN
cord-257662-viy65y72	42	39	tissue	tissue	NN
cord-257662-viy65y72	42	40	damage	damage	NN
cord-257662-viy65y72	42	41	or	or	CC
cord-257662-viy65y72	42	42	cause	cause	VB
cord-257662-viy65y72	42	43	immunopathology	immunopathology	NN
cord-257662-viy65y72	42	44	.	.	.
cord-257662-viy65y72	43	1	NO	no	RB
cord-257662-viy65y72	43	2	has	have	VBZ
cord-257662-viy65y72	43	3	antimicrobial	antimicrobial	JJ
cord-257662-viy65y72	43	4	activity	activity	NN
cord-257662-viy65y72	43	5	against	against	IN
cord-257662-viy65y72	43	6	a	a	DT
cord-257662-viy65y72	43	7	number	number	NN
cord-257662-viy65y72	43	8	of	of	IN
cord-257662-viy65y72	43	9	bacteria	bacteria	NNS
cord-257662-viy65y72	43	10	,	,	,
cord-257662-viy65y72	43	11	parasites	parasite	NNS
cord-257662-viy65y72	43	12	,	,	,
cord-257662-viy65y72	43	13	and	and	CC
cord-257662-viy65y72	43	14	fungi	fungus	NNS
cord-257662-viy65y72	43	15	(	(	-LRB-
cord-257662-viy65y72	43	16	7	7	CD
cord-257662-viy65y72	43	17	,	,	,
cord-257662-viy65y72	43	18	8)	8)	NN
cord-257662-viy65y72	43	19	.	.	.
cord-257662-viy65y72	44	1	Additionally	additionally	RB
cord-257662-viy65y72	44	2	,	,	,
cord-257662-viy65y72	44	3	NO	NO	NNP
cord-257662-viy65y72	44	4	has	have	VBZ
cord-257662-viy65y72	44	5	been	be	VBN
cord-257662-viy65y72	44	6	shown	show	VBN
cord-257662-viy65y72	44	7	to	to	TO
cord-257662-viy65y72	44	8	have	have	VB
cord-257662-viy65y72	44	9	direct	direct	JJ
cord-257662-viy65y72	44	10	antiviral	antiviral	JJ
cord-257662-viy65y72	44	11	effects	effect	NNS
cord-257662-viy65y72	44	12	in	in	IN
cord-257662-viy65y72	44	13	vitro	vitro	FW
cord-257662-viy65y72	44	14	and/or	and/or	CC
cord-257662-viy65y72	44	15	in	in	IN
cord-257662-viy65y72	44	16	vivo	vivo	NN
cord-257662-viy65y72	44	17	against	against	IN
cord-257662-viy65y72	44	18	several	several	JJ
cord-257662-viy65y72	44	19	viruses	virus	NNS
cord-257662-viy65y72	44	20	,	,	,
cord-257662-viy65y72	44	21	including	include	VBG
cord-257662-viy65y72	44	22	DNA	dna	NN
cord-257662-viy65y72	44	23	viruses	virus	NNS
cord-257662-viy65y72	44	24	such	such	JJ
cord-257662-viy65y72	44	25	as	as	IN
cord-257662-viy65y72	44	26	herpes	herpes	NN
cord-257662-viy65y72	44	27	simplex	simplex	NNP
cord-257662-viy65y72	44	28	virus	virus	NN
cord-257662-viy65y72	44	29	type-1	type-1	NN
cord-257662-viy65y72	44	30	(	(	-LRB-
cord-257662-viy65y72	44	31	HSV-1	HSV-1	NNP
cord-257662-viy65y72	44	32	)	)	-RRB-
cord-257662-viy65y72	44	33	,	,	,
cord-257662-viy65y72	44	34	ectromelia	ectromelia	NNP
cord-257662-viy65y72	44	35	virus	virus	NN
cord-257662-viy65y72	44	36	(	(	-LRB-
cord-257662-viy65y72	44	37	EV	EV	NNP
cord-257662-viy65y72	44	38	)	)	-RRB-
cord-257662-viy65y72	44	39	,	,	,
cord-257662-viy65y72	44	40	and	and	CC
cord-257662-viy65y72	44	41	vaccinia	vaccinia	NN
cord-257662-viy65y72	44	42	virus	virus	NN
cord-257662-viy65y72	44	43	(	(	-LRB-
cord-257662-viy65y72	44	44	VV	VV	NNP
cord-257662-viy65y72	44	45	)	)	-RRB-
cord-257662-viy65y72	44	46	(	(	-LRB-
cord-257662-viy65y72	44	47	9	9	CD
cord-257662-viy65y72	44	48	,	,	,
cord-257662-viy65y72	44	49	10	10	CD
cord-257662-viy65y72	44	50	)	)	-RRB-
cord-257662-viy65y72	44	51	,	,	,
cord-257662-viy65y72	44	52	as	as	RB
cord-257662-viy65y72	44	53	well	well	RB
cord-257662-viy65y72	44	54	as	as	IN
cord-257662-viy65y72	44	55	some	some	DT
cord-257662-viy65y72	44	56	RNA	RNA	NNP
cord-257662-viy65y72	44	57	viruses	virus	NNS
cord-257662-viy65y72	44	58	such	such	JJ
cord-257662-viy65y72	44	59	as	as	IN
cord-257662-viy65y72	44	60	vesicular	vesicular	JJ
cord-257662-viy65y72	44	61	stomatitis	stomatitis	NN
cord-257662-viy65y72	44	62	virus	virus	NN
cord-257662-viy65y72	44	63	(	(	-LRB-
cord-257662-viy65y72	44	64	VSV	VSV	NNP
cord-257662-viy65y72	44	65	)	)	-RRB-
cord-257662-viy65y72	44	66	(	(	-LRB-
cord-257662-viy65y72	44	67	11	11	CD
cord-257662-viy65y72	44	68	)	)	-RRB-
cord-257662-viy65y72	44	69	,	,	,
cord-257662-viy65y72	44	70	Japanese	japanese	JJ
cord-257662-viy65y72	44	71	encephalitis	encephalitis	RB
cord-257662-viy65y72	44	72	virus	virus	NN
cord-257662-viy65y72	44	73	(	(	-LRB-
cord-257662-viy65y72	44	74	JEV	JEV	NNP
cord-257662-viy65y72	44	75	)	)	-RRB-
cord-257662-viy65y72	45	1	(	(	-LRB-
cord-257662-viy65y72	45	2	12	12	CD
cord-257662-viy65y72	45	3	)	)	-RRB-
cord-257662-viy65y72	45	4	,	,	,
cord-257662-viy65y72	45	5	dengue	dengue	NN
cord-257662-viy65y72	45	6	virus	virus	NN
cord-257662-viy65y72	45	7	(	(	-LRB-
cord-257662-viy65y72	45	8	DENV	DENV	NNP
cord-257662-viy65y72	45	9	)	)	-RRB-
cord-257662-viy65y72	45	10	(	(	-LRB-
cord-257662-viy65y72	45	11	13	13	CD
cord-257662-viy65y72	45	12	)	)	-RRB-
cord-257662-viy65y72	45	13	,	,	,
cord-257662-viy65y72	45	14	and	and	CC
cord-257662-viy65y72	45	15	coxsackievirus	coxsackievirus	NNP
cord-257662-viy65y72	45	16	(	(	-LRB-
cord-257662-viy65y72	45	17	Table	table	NN
cord-257662-viy65y72	45	18	1	1	CD
cord-257662-viy65y72	45	19	)	)	-RRB-
cord-257662-viy65y72	46	1	(	(	-LRB-
cord-257662-viy65y72	46	2	14	14	CD
cord-257662-viy65y72	46	3	)	)	-RRB-
cord-257662-viy65y72	47	1	(	(	-LRB-
cord-257662-viy65y72	47	2	15	15	CD
cord-257662-viy65y72	47	3	)	)	-RRB-
cord-257662-viy65y72	47	4	(	(	-LRB-
cord-257662-viy65y72	47	5	16	16	CD
cord-257662-viy65y72	47	6	)	)	-RRB-
cord-257662-viy65y72	47	7	(	(	-LRB-
cord-257662-viy65y72	47	8	17	17	CD
cord-257662-viy65y72	47	9	)	)	-RRB-
cord-257662-viy65y72	47	10	.	.	.
cord-257662-viy65y72	48	1	There	there	EX
cord-257662-viy65y72	48	2	are	be	VBP
cord-257662-viy65y72	48	3	several	several	JJ
cord-257662-viy65y72	48	4	advantages	advantage	NNS
cord-257662-viy65y72	48	5	of	of	IN
cord-257662-viy65y72	48	6	using	use	VBG
cord-257662-viy65y72	48	7	NO	no	RB
cord-257662-viy65y72	48	8	as	as	IN
cord-257662-viy65y72	48	9	an	an	DT
cord-257662-viy65y72	48	10	antiviral	antiviral	JJ
cord-257662-viy65y72	48	11	agent	agent	NN
cord-257662-viy65y72	48	12	.	.	.
cord-257662-viy65y72	49	1	For	for	IN
cord-257662-viy65y72	49	2	instance	instance	NN
cord-257662-viy65y72	49	3	,	,	,
cord-257662-viy65y72	49	4	unlike	unlike	IN
cord-257662-viy65y72	49	5	complement	complement	NN
cord-257662-viy65y72	49	6	and	and	CC
cord-257662-viy65y72	49	7	antibody	antibody	NN
cord-257662-viy65y72	49	8	,	,	,
cord-257662-viy65y72	49	9	NO	no	UH
cord-257662-viy65y72	49	10	can	can	MD
cord-257662-viy65y72	49	11	readily	readily	RB
cord-257662-viy65y72	49	12	pass	pass	VB
cord-257662-viy65y72	49	13	through	through	RP
cord-257662-viy65y72	49	14	cellular	cellular	JJ
cord-257662-viy65y72	49	15	membranes	membrane	NNS
cord-257662-viy65y72	49	16	into	into	IN
cord-257662-viy65y72	49	17	neighboring	neighboring	NN
cord-257662-viy65y72	49	18	cells	cell	NNS
cord-257662-viy65y72	49	19	as	as	RB
cord-257662-viy65y72	49	20	well	well	RB
cord-257662-viy65y72	49	21	as	as	IN
cord-257662-viy65y72	49	22	some	some	DT
cord-257662-viy65y72	49	23	viruses	virus	NNS
cord-257662-viy65y72	49	24	.	.	.
cord-257662-viy65y72	50	1	Additionally	additionally	RB
cord-257662-viy65y72	50	2	,	,	,
cord-257662-viy65y72	50	3	NO	no	UH
cord-257662-viy65y72	50	4	is	be	VBZ
cord-257662-viy65y72	50	5	likely	likely	JJ
cord-257662-viy65y72	50	6	to	to	TO
cord-257662-viy65y72	50	7	act	act	VB
cord-257662-viy65y72	50	8	on	on	IN
cord-257662-viy65y72	50	9	a	a	DT
cord-257662-viy65y72	50	10	variety	variety	NN
cord-257662-viy65y72	50	11	of	of	IN
cord-257662-viy65y72	50	12	both	both	DT
cord-257662-viy65y72	50	13	viral	viral	JJ
cord-257662-viy65y72	50	14	and	and	CC
cord-257662-viy65y72	50	15	virally	virally	RB
cord-257662-viy65y72	50	16	exploited	exploit	VBN
cord-257662-viy65y72	50	17	cellular	cellular	JJ
cord-257662-viy65y72	50	18	targets	target	NNS
cord-257662-viy65y72	50	19	,	,	,
cord-257662-viy65y72	50	20	inhibiting	inhibit	VBG
cord-257662-viy65y72	50	21	viral	viral	JJ
cord-257662-viy65y72	50	22	replication	replication	NN
cord-257662-viy65y72	50	23	as	as	RB
cord-257662-viy65y72	50	24	well	well	RB
cord-257662-viy65y72	50	25	as	as	IN
cord-257662-viy65y72	50	26	limiting	limit	VBG
cord-257662-viy65y72	50	27	the	the	DT
cord-257662-viy65y72	50	28	capacity	capacity	NN
cord-257662-viy65y72	50	29	of	of	IN
cord-257662-viy65y72	50	30	viruses	virus	NNS
cord-257662-viy65y72	50	31	to	to	TO
cord-257662-viy65y72	50	32	develop	develop	VB
cord-257662-viy65y72	50	33	resistance	resistance	NN
cord-257662-viy65y72	50	34	.	.	.
cord-257662-viy65y72	51	1	Lastly	lastly	RB
cord-257662-viy65y72	51	2	,	,	,
cord-257662-viy65y72	51	3	the	the	DT
cord-257662-viy65y72	51	4	effect	effect	NN
cord-257662-viy65y72	51	5	of	of	IN
cord-257662-viy65y72	51	6	NO	no	DT
cord-257662-viy65y72	51	7	is	be	VBZ
cord-257662-viy65y72	51	8	independent	independent	JJ
cord-257662-viy65y72	51	9	of	of	IN
cord-257662-viy65y72	51	10	immune	immune	JJ
cord-257662-viy65y72	51	11	recognition	recognition	NN
cord-257662-viy65y72	51	12	of	of	IN
cord-257662-viy65y72	51	13	the	the	DT
cord-257662-viy65y72	51	14	infected	infected	JJ
cord-257662-viy65y72	51	15	cell	cell	NN
cord-257662-viy65y72	51	16	,	,	,
cord-257662-viy65y72	51	17	in	in	IN
cord-257662-viy65y72	51	18	contrast	contrast	NN
cord-257662-viy65y72	51	19	to	to	IN
cord-257662-viy65y72	51	20	that	that	DT
cord-257662-viy65y72	51	21	of	of	IN
cord-257662-viy65y72	51	22	antiviral	antiviral	JJ
cord-257662-viy65y72	51	23	lymphocytes	lymphocyte	NNS
cord-257662-viy65y72	51	24	,	,	,
cord-257662-viy65y72	51	25	which	which	WDT
cord-257662-viy65y72	51	26	could	could	MD
cord-257662-viy65y72	51	27	be	be	VB
cord-257662-viy65y72	51	28	important	important	JJ
cord-257662-viy65y72	51	29	in	in	IN
cord-257662-viy65y72	51	30	virusinfected	virusinfected	JJ
cord-257662-viy65y72	51	31	cells	cell	NNS
cord-257662-viy65y72	51	32	where	where	WRB
cord-257662-viy65y72	51	33	expression	expression	NN
cord-257662-viy65y72	51	34	of	of	IN
cord-257662-viy65y72	51	35	MHC	MHC	NNP
cord-257662-viy65y72	51	36	class	class	NN
cord-257662-viy65y72	51	37	I	-PRON-	PRP
cord-257662-viy65y72	51	38	molecules	molecule	NNS
cord-257662-viy65y72	51	39	may	may	MD
cord-257662-viy65y72	51	40	be	be	VB
cord-257662-viy65y72	51	41	downregulated	downregulate	VBN
cord-257662-viy65y72	51	42	and	and	CC
cord-257662-viy65y72	51	43	in	in	IN
cord-257662-viy65y72	51	44	some	some	DT
cord-257662-viy65y72	51	45	virally	virally	RB
cord-257662-viy65y72	51	46	infected	infect	VBN
cord-257662-viy65y72	51	47	tissues	tissue	NNS
cord-257662-viy65y72	51	48	such	such	JJ
cord-257662-viy65y72	51	49	as	as	IN
cord-257662-viy65y72	51	50	the	the	DT
cord-257662-viy65y72	51	51	brain	brain	NN
cord-257662-viy65y72	51	52	where	where	WRB
cord-257662-viy65y72	51	53	expression	expression	NN
cord-257662-viy65y72	51	54	of	of	IN
cord-257662-viy65y72	51	55	MHC	MHC	NNP
cord-257662-viy65y72	51	56	class	class	NN
cord-257662-viy65y72	51	57	I	i	NN
cord-257662-viy65y72	51	58	and	and	CC
cord-257662-viy65y72	51	59	II	II	NNP
cord-257662-viy65y72	51	60	molecules	molecule	NNS
cord-257662-viy65y72	51	61	is	be	VBZ
cord-257662-viy65y72	51	62	limited	limited	JJ
cord-257662-viy65y72	51	63	.	.	.
cord-257662-viy65y72	52	1	In	in	IN
cord-257662-viy65y72	52	2	initial	initial	JJ
cord-257662-viy65y72	52	3	studies	study	NNS
cord-257662-viy65y72	52	4	in	in	IN
cord-257662-viy65y72	52	5	vitro	vitro	FW
cord-257662-viy65y72	52	6	,	,	,
cord-257662-viy65y72	52	7	inhibition	inhibition	NN
cord-257662-viy65y72	52	8	of	of	IN
cord-257662-viy65y72	52	9	EV	EV	NNP
cord-257662-viy65y72	52	10	,	,	,
cord-257662-viy65y72	52	11	VV	VV	NNP
cord-257662-viy65y72	52	12	,	,	,
cord-257662-viy65y72	52	13	and	and	CC
cord-257662-viy65y72	52	14	HSV-1	hsv-1	NN
cord-257662-viy65y72	52	15	replication	replication	NN
cord-257662-viy65y72	52	16	in	in	IN
cord-257662-viy65y72	52	17	mouse	mouse	NN
cord-257662-viy65y72	52	18	RAW	raw	JJ
cord-257662-viy65y72	52	19	264.7	264.7	CD
cord-257662-viy65y72	52	20	macrophages	macrophage	NNS
cord-257662-viy65y72	52	21	and	and	CC
cord-257662-viy65y72	52	22	in	in	IN
cord-257662-viy65y72	52	23	primary	primary	JJ
cord-257662-viy65y72	52	24	mouse	mouse	NN
cord-257662-viy65y72	52	25	macrophages	macrophage	NNS
cord-257662-viy65y72	52	26	following	follow	VBG
cord-257662-viy65y72	52	27	IFN	IFN	NNP
cord-257662-viy65y72	52	28	-	-	HYPH
cord-257662-viy65y72	52	29	γ	γ	NN
cord-257662-viy65y72	52	30	treatment	treatment	NN
cord-257662-viy65y72	52	31	was	be	VBD
cord-257662-viy65y72	52	32	shown	show	VBN
cord-257662-viy65y72	52	33	to	to	TO
cord-257662-viy65y72	52	34	be	be	VB
cord-257662-viy65y72	52	35	largely	largely	RB
cord-257662-viy65y72	52	36	dependent	dependent	JJ
cord-257662-viy65y72	52	37	on	on	IN
cord-257662-viy65y72	52	38	NO	no	DT
cord-257662-viy65y72	52	39	production	production	NN
cord-257662-viy65y72	52	40	(	(	-LRB-
cord-257662-viy65y72	52	41	9	9	CD
cord-257662-viy65y72	52	42	,	,	,
cord-257662-viy65y72	52	43	10	10	CD
cord-257662-viy65y72	52	44	)	)	-RRB-
cord-257662-viy65y72	52	45	.	.	.
cord-257662-viy65y72	53	1	Additionally	additionally	RB
cord-257662-viy65y72	53	2	,	,	,
cord-257662-viy65y72	53	3	pharmacologic	pharmacologic	JJ
cord-257662-viy65y72	53	4	inhibition	inhibition	NN
cord-257662-viy65y72	53	5	of	of	IN
cord-257662-viy65y72	53	6	NOS	NOS	NNP
cord-257662-viy65y72	53	7	or	or	CC
cord-257662-viy65y72	53	8	genetic	genetic	JJ
cord-257662-viy65y72	53	9	deletion	deletion	NN
cord-257662-viy65y72	53	10	of	of	IN
cord-257662-viy65y72	53	11	Nos2	Nos2	NNP
cord-257662-viy65y72	53	12	resulted	result	VBD
cord-257662-viy65y72	53	13	in	in	IN
cord-257662-viy65y72	53	14	increased	increase	VBN
cord-257662-viy65y72	53	15	viral	viral	JJ
cord-257662-viy65y72	53	16	titers	titer	NNS
cord-257662-viy65y72	53	17	and	and	CC
cord-257662-viy65y72	53	18	mortality	mortality	NN
cord-257662-viy65y72	53	19	following	follow	VBG
cord-257662-viy65y72	53	20	EV	ev	NN
cord-257662-viy65y72	53	21	infection	infection	NN
cord-257662-viy65y72	53	22	in	in	IN
cord-257662-viy65y72	53	23	mice	mouse	NNS
cord-257662-viy65y72	53	24	(	(	-LRB-
cord-257662-viy65y72	53	25	9	9	CD
cord-257662-viy65y72	53	26	,	,	,
cord-257662-viy65y72	53	27	18	18	CD
cord-257662-viy65y72	53	28	)	)	-RRB-
cord-257662-viy65y72	53	29	.	.	.
cord-257662-viy65y72	54	1	Moreover	moreover	RB
cord-257662-viy65y72	54	2	,	,	,
cord-257662-viy65y72	54	3	NO	no	DT
cord-257662-viy65y72	54	4	affects	affect	VBZ
cord-257662-viy65y72	54	5	several	several	JJ
cord-257662-viy65y72	54	6	events	event	NNS
cord-257662-viy65y72	54	7	in	in	IN
cord-257662-viy65y72	54	8	the	the	DT
cord-257662-viy65y72	54	9	late	late	JJ
cord-257662-viy65y72	54	10	stages	stage	NNS
cord-257662-viy65y72	54	11	of	of	IN
cord-257662-viy65y72	54	12	the	the	DT
cord-257662-viy65y72	54	13	life	life	NN
cord-257662-viy65y72	54	14	cycle	cycle	NN
cord-257662-viy65y72	54	15	of	of	IN
cord-257662-viy65y72	54	16	VV	VV	NNP
cord-257662-viy65y72	54	17	,	,	,
cord-257662-viy65y72	54	18	including	include	VBG
cord-257662-viy65y72	54	19	viral	viral	JJ
cord-257662-viy65y72	54	20	DNA	dna	NN
cord-257662-viy65y72	54	21	replication	replication	NN
cord-257662-viy65y72	54	22	,	,	,
cord-257662-viy65y72	54	23	viral	viral	JJ
cord-257662-viy65y72	54	24	protein	protein	NN
cord-257662-viy65y72	54	25	synthesis	synthesis	NN
cord-257662-viy65y72	54	26	,	,	,
cord-257662-viy65y72	54	27	and	and	CC
cord-257662-viy65y72	54	28	virion	virion	NN
cord-257662-viy65y72	54	29	maturation	maturation	NN
cord-257662-viy65y72	54	30	in	in	IN
cord-257662-viy65y72	54	31	vitro	vitro	FW
cord-257662-viy65y72	54	32	(	(	-LRB-
cord-257662-viy65y72	54	33	32	32	CD
cord-257662-viy65y72	54	34	)	)	-RRB-
cord-257662-viy65y72	54	35	.	.	.
cord-257662-viy65y72	55	1	These	these	DT
cord-257662-viy65y72	55	2	studies	study	NNS
cord-257662-viy65y72	55	3	provided	provide	VBD
cord-257662-viy65y72	55	4	some	some	DT
cord-257662-viy65y72	55	5	of	of	IN
cord-257662-viy65y72	55	6	the	the	DT
cord-257662-viy65y72	55	7	first	first	JJ
cord-257662-viy65y72	55	8	evidence	evidence	NN
cord-257662-viy65y72	55	9	that	that	IN
cord-257662-viy65y72	55	10	macrophage	macrophage	NN
cord-257662-viy65y72	55	11	-	-	HYPH
cord-257662-viy65y72	55	12	produced	produce	VBN
cord-257662-viy65y72	55	13	NO	no	DT
cord-257662-viy65y72	55	14	has	have	VBZ
cord-257662-viy65y72	55	15	direct	direct	JJ
cord-257662-viy65y72	55	16	antiviral	antiviral	JJ
cord-257662-viy65y72	55	17	effects	effect	NNS
cord-257662-viy65y72	55	18	.	.	.
cord-257662-viy65y72	56	1	In	in	IN
cord-257662-viy65y72	56	2	addition	addition	NN
cord-257662-viy65y72	56	3	to	to	IN
cord-257662-viy65y72	56	4	inhibiting	inhibit	VBG
cord-257662-viy65y72	56	5	HSV-1	HSV-1	NNP
cord-257662-viy65y72	56	6	replication	replication	NN
cord-257662-viy65y72	56	7	in	in	IN
cord-257662-viy65y72	56	8	vitro	vitro	FW
cord-257662-viy65y72	56	9	,	,	,
cord-257662-viy65y72	56	10	macrophage	macrophage	NN
cord-257662-viy65y72	56	11	-	-	HYPH
cord-257662-viy65y72	56	12	derived	derive	VBN
cord-257662-viy65y72	56	13	NO	no	NN
cord-257662-viy65y72	56	14	has	have	VBZ
cord-257662-viy65y72	56	15	been	be	VBN
cord-257662-viy65y72	56	16	shown	show	VBN
cord-257662-viy65y72	56	17	to	to	TO
cord-257662-viy65y72	56	18	have	have	VB
cord-257662-viy65y72	56	19	anti	anti	JJ
cord-257662-viy65y72	56	20	-	-	JJ
cord-257662-viy65y72	56	21	HSV	hsv	JJ
cord-257662-viy65y72	56	22	properties	property	NNS
cord-257662-viy65y72	56	23	in	in	IN
cord-257662-viy65y72	56	24	vivo	vivo	NN
cord-257662-viy65y72	56	25	.	.	.
cord-257662-viy65y72	57	1	In	in	IN
cord-257662-viy65y72	57	2	a	a	DT
cord-257662-viy65y72	57	3	mouse	mouse	NN
cord-257662-viy65y72	57	4	model	model	NN
cord-257662-viy65y72	57	5	of	of	IN
cord-257662-viy65y72	57	6	HSV-1-mediated	hsv-1-mediated	JJ
cord-257662-viy65y72	57	7	corneal	corneal	JJ
cord-257662-viy65y72	57	8	disease	disease	NN
cord-257662-viy65y72	57	9	,	,	,
cord-257662-viy65y72	57	10	iNOS	iNOS	NNP
cord-257662-viy65y72	57	11	was	be	VBD
cord-257662-viy65y72	57	12	highly	highly	RB
cord-257662-viy65y72	57	13	induced	induce	VBN
cord-257662-viy65y72	57	14	in	in	IN
cord-257662-viy65y72	57	15	the	the	DT
cord-257662-viy65y72	57	16	trigeminal	trigeminal	JJ
cord-257662-viy65y72	57	17	ganglion	ganglion	NN
cord-257662-viy65y72	57	18	(	(	-LRB-
cord-257662-viy65y72	57	19	TG	TG	NNP
cord-257662-viy65y72	57	20	)	)	-RRB-
cord-257662-viy65y72	57	21	of	of	IN
cord-257662-viy65y72	57	22	HSV-1-infected	hsv-1-infecte	VBN
cord-257662-viy65y72	57	23	mice	mouse	NNS
cord-257662-viy65y72	57	24	,	,	,
cord-257662-viy65y72	57	25	and	and	CC
cord-257662-viy65y72	57	26	its	-PRON-	PRP$
cord-257662-viy65y72	57	27	expression	expression	NN
cord-257662-viy65y72	57	28	was	be	VBD
cord-257662-viy65y72	57	29	markedly	markedly	RB
cord-257662-viy65y72	57	30	reduced	reduce	VBN
cord-257662-viy65y72	57	31	in	in	IN
cord-257662-viy65y72	57	32	mice	mouse	NNS
cord-257662-viy65y72	57	33	depleted	deplete	VBN
cord-257662-viy65y72	57	34	of	of	IN
cord-257662-viy65y72	57	35	macrophages	macrophage	NNS
cord-257662-viy65y72	57	36	(	(	-LRB-
cord-257662-viy65y72	57	37	22	22	CD
cord-257662-viy65y72	57	38	)	)	-RRB-
cord-257662-viy65y72	57	39	.	.	.
cord-257662-viy65y72	58	1	Depletion	depletion	NN
cord-257662-viy65y72	58	2	of	of	IN
cord-257662-viy65y72	58	3	macrophages	macrophage	NNS
cord-257662-viy65y72	58	4	prior	prior	RB
cord-257662-viy65y72	58	5	to	to	IN
cord-257662-viy65y72	58	6	HSV-1	hsv-1	NN
cord-257662-viy65y72	58	7	infection	infection	NN
cord-257662-viy65y72	58	8	resulted	result	VBD
cord-257662-viy65y72	58	9	in	in	IN
cord-257662-viy65y72	58	10	markedly	markedly	RB
cord-257662-viy65y72	58	11	reduced	reduce	VBN
cord-257662-viy65y72	58	12	iNOS	inos	JJ
cord-257662-viy65y72	58	13	expression	expression	NN
cord-257662-viy65y72	58	14	and	and	CC
cord-257662-viy65y72	58	15	higher	high	JJR
cord-257662-viy65y72	58	16	viral	viral	JJ
cord-257662-viy65y72	58	17	loads	load	NNS
cord-257662-viy65y72	58	18	in	in	IN
cord-257662-viy65y72	58	19	the	the	DT
cord-257662-viy65y72	58	20	TG	TG	NNP
cord-257662-viy65y72	58	21	of	of	IN
cord-257662-viy65y72	58	22	infected	infected	JJ
cord-257662-viy65y72	58	23	mice	mouse	NNS
cord-257662-viy65y72	58	24	(	(	-LRB-
cord-257662-viy65y72	58	25	22	22	CD
cord-257662-viy65y72	58	26	,	,	,
cord-257662-viy65y72	58	27	23	23	CD
cord-257662-viy65y72	58	28	)	)	-RRB-
cord-257662-viy65y72	58	29	,	,	,
cord-257662-viy65y72	58	30	suggesting	suggest	VBG
cord-257662-viy65y72	58	31	that	that	IN
cord-257662-viy65y72	58	32	macrophages	macrophage	NNS
cord-257662-viy65y72	58	33	were	be	VBD
cord-257662-viy65y72	58	34	the	the	DT
cord-257662-viy65y72	58	35	main	main	JJ
cord-257662-viy65y72	58	36	source	source	NN
cord-257662-viy65y72	58	37	of	of	IN
cord-257662-viy65y72	58	38	iNOS	inos	JJ
cord-257662-viy65y72	58	39	expression	expression	NN
cord-257662-viy65y72	58	40	in	in	IN
cord-257662-viy65y72	58	41	the	the	DT
cord-257662-viy65y72	58	42	affected	affect	VBN
cord-257662-viy65y72	58	43	tissues	tissue	NNS
cord-257662-viy65y72	58	44	following	follow	VBG
cord-257662-viy65y72	58	45	HSV-1	hsv-1	NN
cord-257662-viy65y72	58	46	infection	infection	NN
cord-257662-viy65y72	58	47	and	and	CC
cord-257662-viy65y72	58	48	that	that	IN
cord-257662-viy65y72	58	49	NO	no	DT
cord-257662-viy65y72	58	50	had	have	VBD
cord-257662-viy65y72	58	51	important	important	JJ
cord-257662-viy65y72	58	52	anti	anti	JJ
cord-257662-viy65y72	58	53	-	-	JJ
cord-257662-viy65y72	58	54	HSV-1	hsv-1	JJ
cord-257662-viy65y72	58	55	properties	property	NNS
cord-257662-viy65y72	58	56	in	in	IN
cord-257662-viy65y72	58	57	vivo	vivo	NN
cord-257662-viy65y72	58	58	.	.	.
cord-257662-viy65y72	59	1	Consistent	consistent	JJ
cord-257662-viy65y72	59	2	with	with	IN
cord-257662-viy65y72	59	3	these	these	DT
cord-257662-viy65y72	59	4	data	datum	NNS
cord-257662-viy65y72	59	5	,	,	,
cord-257662-viy65y72	59	6	inhibition	inhibition	NN
cord-257662-viy65y72	59	7	of	of	IN
cord-257662-viy65y72	59	8	NOS	NOS	NNP
cord-257662-viy65y72	59	9	activity	activity	NN
cord-257662-viy65y72	59	10	resulted	result	VBD
cord-257662-viy65y72	59	11	in	in	IN
cord-257662-viy65y72	59	12	increased	increase	VBN
cord-257662-viy65y72	59	13	viral	viral	JJ
cord-257662-viy65y72	59	14	loads	load	NNS
cord-257662-viy65y72	59	15	in	in	IN
cord-257662-viy65y72	59	16	the	the	DT
cord-257662-viy65y72	59	17	TG	TG	NNP
cord-257662-viy65y72	59	18	(	(	-LRB-
cord-257662-viy65y72	59	19	22	22	CD
cord-257662-viy65y72	59	20	)	)	-RRB-
cord-257662-viy65y72	59	21	.	.	.
cord-257662-viy65y72	60	1	Additional	additional	JJ
cord-257662-viy65y72	60	2	studies	study	NNS
cord-257662-viy65y72	60	3	showed	show	VBD
cord-257662-viy65y72	60	4	that	that	IN
cord-257662-viy65y72	60	5	F4/80	F4/80	NNPS
cord-257662-viy65y72	60	6	+	+	CC
cord-257662-viy65y72	60	7	GR-1	gr-1	NN
cord-257662-viy65y72	60	8	+	+	CC
cord-257662-viy65y72	60	9	inflammatory	inflammatory	JJ
cord-257662-viy65y72	60	10	monocytes	monocyte	NNS
cord-257662-viy65y72	60	11	were	be	VBD
cord-257662-viy65y72	60	12	recruited	recruit	VBN
cord-257662-viy65y72	60	13	to	to	IN
cord-257662-viy65y72	60	14	the	the	DT
cord-257662-viy65y72	60	15	eye	eye	NN
cord-257662-viy65y72	60	16	via	via	IN
cord-257662-viy65y72	60	17	an	an	DT
cord-257662-viy65y72	60	18	IFN	IFN	NNP
cord-257662-viy65y72	60	19	-	-	HYPH
cord-257662-viy65y72	60	20	α	α	NN
cord-257662-viy65y72	60	21	-	-	HYPH
cord-257662-viy65y72	60	22	driven	drive	VBN
cord-257662-viy65y72	60	23	CCL2	CCL2	NNP
cord-257662-viy65y72	60	24	gradient	gradient	NN
cord-257662-viy65y72	60	25	and	and	CC
cord-257662-viy65y72	60	26	restricted	restrict	VBD
cord-257662-viy65y72	60	27	HSV-1	hsv-1	NN
cord-257662-viy65y72	60	28	replication	replication	NN
cord-257662-viy65y72	60	29	in	in	IN
cord-257662-viy65y72	60	30	that	that	DT
cord-257662-viy65y72	60	31	tissue	tissue	NN
cord-257662-viy65y72	60	32	via	via	IN
cord-257662-viy65y72	60	33	NO	no	DT
cord-257662-viy65y72	60	34	production	production	NN
cord-257662-viy65y72	60	35	(	(	-LRB-
cord-257662-viy65y72	60	36	24	24	CD
cord-257662-viy65y72	60	37	)	)	-RRB-
cord-257662-viy65y72	60	38	.	.	.
cord-257662-viy65y72	61	1	It	-PRON-	PRP
cord-257662-viy65y72	61	2	was	be	VBD
cord-257662-viy65y72	61	3	further	further	RB
cord-257662-viy65y72	61	4	shown	show	VBN
cord-257662-viy65y72	61	5	that	that	IN
cord-257662-viy65y72	61	6	NO	no	DT
cord-257662-viy65y72	61	7	production	production	NN
cord-257662-viy65y72	61	8	by	by	IN
cord-257662-viy65y72	61	9	F4/80	F4/80	NNS
cord-257662-viy65y72	61	10	+	+	CC
cord-257662-viy65y72	61	11	macrophages	macrophage	NNS
cord-257662-viy65y72	61	12	in	in	IN
cord-257662-viy65y72	61	13	the	the	DT
cord-257662-viy65y72	61	14	brains	brain	NNS
cord-257662-viy65y72	61	15	of	of	IN
cord-257662-viy65y72	61	16	HSV-1-infected	hsv-1-infecte	VBN
cord-257662-viy65y72	61	17	mice	mouse	NNS
cord-257662-viy65y72	61	18	blocked	block	VBD
cord-257662-viy65y72	61	19	viral	viral	JJ
cord-257662-viy65y72	61	20	replication	replication	NN
cord-257662-viy65y72	61	21	in	in	IN
cord-257662-viy65y72	61	22	a	a	DT
cord-257662-viy65y72	61	23	partially	partially	RB
cord-257662-viy65y72	61	24	TLR2-and	TLR2-and	NNP
cord-257662-viy65y72	61	25	TLR9-dependent	TLR9-dependent	NNP
cord-257662-viy65y72	61	26	mechanism	mechanism	NN
cord-257662-viy65y72	61	27	(	(	-LRB-
cord-257662-viy65y72	61	28	25	25	CD
cord-257662-viy65y72	61	29	)	)	-RRB-
cord-257662-viy65y72	61	30	.	.	.
cord-257662-viy65y72	62	1	Finally	finally	RB
cord-257662-viy65y72	62	2	,	,	,
cord-257662-viy65y72	62	3	following	follow	VBG
cord-257662-viy65y72	62	4	footpad	footpad	NN
cord-257662-viy65y72	62	5	inoculation	inoculation	NN
cord-257662-viy65y72	62	6	,	,	,
cord-257662-viy65y72	62	7	HSV-1-infected	hsv-1-infecte	VBN
cord-257662-viy65y72	63	1	Nos2	Nos2	NNP
cord-257662-viy65y72	63	2	−/−	−/−	NNP
cord-257662-viy65y72	63	3	mice	mouse	NNS
cord-257662-viy65y72	63	4	displayed	display	VBD
cord-257662-viy65y72	63	5	a	a	DT
cord-257662-viy65y72	63	6	delayed	delay	VBN
cord-257662-viy65y72	63	7	clearance	clearance	NN
cord-257662-viy65y72	63	8	of	of	IN
cord-257662-viy65y72	63	9	virus	virus	NN
cord-257662-viy65y72	63	10	from	from	IN
cord-257662-viy65y72	63	11	the	the	DT
cord-257662-viy65y72	63	12	dorsal	dorsal	JJ
cord-257662-viy65y72	63	13	root	root	NN
cord-257662-viy65y72	63	14	ganglia	ganglion	NNS
cord-257662-viy65y72	63	15	(	(	-LRB-
cord-257662-viy65y72	63	16	DRG	DRG	NNP
cord-257662-viy65y72	63	17	)	)	-RRB-
cord-257662-viy65y72	63	18	and	and	CC
cord-257662-viy65y72	63	19	exhibited	exhibit	VBD
cord-257662-viy65y72	63	20	an	an	DT
cord-257662-viy65y72	63	21	increase	increase	NN
cord-257662-viy65y72	63	22	in	in	IN
cord-257662-viy65y72	63	23	the	the	DT
cord-257662-viy65y72	63	24	frequency	frequency	NN
cord-257662-viy65y72	63	25	of	of	IN
cord-257662-viy65y72	63	26	virus	virus	NN
cord-257662-viy65y72	63	27	reactivation	reactivation	NN
cord-257662-viy65y72	63	28	in	in	IN
cord-257662-viy65y72	63	29	DRG	DRG	NNP
cord-257662-viy65y72	63	30	(	(	-LRB-
cord-257662-viy65y72	63	31	26	26	CD
cord-257662-viy65y72	63	32	)	)	-RRB-
cord-257662-viy65y72	63	33	.	.	.
cord-257662-viy65y72	64	1	The	the	DT
cord-257662-viy65y72	64	2	reactivity	reactivity	NN
cord-257662-viy65y72	64	3	of	of	IN
cord-257662-viy65y72	64	4	NO	no	NN
cord-257662-viy65y72	64	5	and	and	CC
cord-257662-viy65y72	64	6	its	-PRON-	PRP$
cord-257662-viy65y72	64	7	higher	high	JJR
cord-257662-viy65y72	64	8	oxides	oxide	NNS
cord-257662-viy65y72	64	9	and	and	CC
cord-257662-viy65y72	64	10	nitrosothiol	nitrosothiol	NNP
cord-257662-viy65y72	64	11	products	products	NNPS
cord-257662-viy65y72	64	12	(	(	-LRB-
cord-257662-viy65y72	64	13	84	84	CD
cord-257662-viy65y72	64	14	)	)	-RRB-
cord-257662-viy65y72	64	15	makes	make	VBZ
cord-257662-viy65y72	64	16	it	-PRON-	PRP
cord-257662-viy65y72	64	17	likely	likely	JJ
cord-257662-viy65y72	64	18	that	that	IN
cord-257662-viy65y72	64	19	a	a	DT
cord-257662-viy65y72	64	20	variety	variety	NN
cord-257662-viy65y72	64	21	of	of	IN
cord-257662-viy65y72	64	22	molecular	molecular	JJ
cord-257662-viy65y72	64	23	targets	target	NNS
cord-257662-viy65y72	64	24	are	be	VBP
cord-257662-viy65y72	64	25	involved	involve	VBN
cord-257662-viy65y72	64	26	in	in	IN
cord-257662-viy65y72	64	27	its	-PRON-	PRP$
cord-257662-viy65y72	64	28	antiviral	antiviral	JJ
cord-257662-viy65y72	64	29	action	action	NN
cord-257662-viy65y72	64	30	.	.	.
cord-257662-viy65y72	65	1	It	-PRON-	PRP
cord-257662-viy65y72	65	2	has	have	VBZ
cord-257662-viy65y72	65	3	been	be	VBN
cord-257662-viy65y72	65	4	shown	show	VBN
cord-257662-viy65y72	65	5	that	that	IN
cord-257662-viy65y72	65	6	NO	no	NN
cord-257662-viy65y72	65	7	can	can	MD
cord-257662-viy65y72	65	8	inhibit	inhibit	VB
cord-257662-viy65y72	65	9	ribonucleotide	ribonucleotide	NN
cord-257662-viy65y72	65	10	reductase	reductase	NN
cord-257662-viy65y72	65	11	(	(	-LRB-
cord-257662-viy65y72	65	12	85	85	CD
cord-257662-viy65y72	65	13	,	,	,
cord-257662-viy65y72	65	14	86	86	CD
cord-257662-viy65y72	65	15	)	)	-RRB-
cord-257662-viy65y72	65	16	,	,	,
cord-257662-viy65y72	65	17	a	a	DT
cord-257662-viy65y72	65	18	rate	rate	NN
cord-257662-viy65y72	65	19	-	-	HYPH
cord-257662-viy65y72	65	20	limiting	limit	VBG
cord-257662-viy65y72	65	21	enzyme	enzyme	NN
cord-257662-viy65y72	65	22	in	in	IN
cord-257662-viy65y72	65	23	DNA	dna	NN
cord-257662-viy65y72	65	24	synthesis	synthesis	NN
cord-257662-viy65y72	65	25	,	,	,
cord-257662-viy65y72	65	26	and	and	CC
cord-257662-viy65y72	65	27	NO	no	DT
cord-257662-viy65y72	65	28	can	can	MD
cord-257662-viy65y72	65	29	lead	lead	VB
cord-257662-viy65y72	65	30	to	to	IN
cord-257662-viy65y72	65	31	the	the	DT
cord-257662-viy65y72	65	32	deamination	deamination	NN
cord-257662-viy65y72	65	33	of	of	IN
cord-257662-viy65y72	65	34	mammalian	mammalian	JJ
cord-257662-viy65y72	65	35	and	and	CC
cord-257662-viy65y72	65	36	bacterial	bacterial	JJ
cord-257662-viy65y72	65	37	DNA	dna	NN
cord-257662-viy65y72	65	38	(	(	-LRB-
cord-257662-viy65y72	65	39	87	87	CD
cord-257662-viy65y72	65	40	,	,	,
cord-257662-viy65y72	65	41	88	88	CD
cord-257662-viy65y72	65	42	)	)	-RRB-
cord-257662-viy65y72	65	43	,	,	,
cord-257662-viy65y72	65	44	which	which	WDT
cord-257662-viy65y72	65	45	may	may	MD
cord-257662-viy65y72	65	46	be	be	VB
cord-257662-viy65y72	65	47	important	important	JJ
cord-257662-viy65y72	65	48	antiviral	antiviral	JJ
cord-257662-viy65y72	65	49	mechanisms	mechanism	NNS
cord-257662-viy65y72	65	50	.	.	.
cord-257662-viy65y72	66	1	Indeed	indeed	RB
cord-257662-viy65y72	66	2	,	,	,
cord-257662-viy65y72	66	3	HSV-1	HSV-1	NNP
cord-257662-viy65y72	66	4	encodes	encode	VBZ
cord-257662-viy65y72	66	5	its	-PRON-	PRP$
cord-257662-viy65y72	66	6	own	own	JJ
cord-257662-viy65y72	66	7	ribonucleotide	ribonucleotide	NN
cord-257662-viy65y72	66	8	reductase	reductase	NN
cord-257662-viy65y72	66	9	and	and	CC
cord-257662-viy65y72	66	10	although	although	IN
cord-257662-viy65y72	66	11	it	-PRON-	PRP
cord-257662-viy65y72	66	12	is	be	VBZ
cord-257662-viy65y72	66	13	not	not	RB
cord-257662-viy65y72	66	14	required	require	VBN
cord-257662-viy65y72	66	15	for	for	IN
cord-257662-viy65y72	66	16	HSV-1	hsv-1	NN
cord-257662-viy65y72	66	17	replication	replication	NN
cord-257662-viy65y72	66	18	in	in	IN
cord-257662-viy65y72	66	19	vitro	vitro	FW
cord-257662-viy65y72	66	20	,	,	,
cord-257662-viy65y72	66	21	it	-PRON-	PRP
cord-257662-viy65y72	66	22	is	be	VBZ
cord-257662-viy65y72	66	23	necessary	necessary	JJ
cord-257662-viy65y72	66	24	under	under	IN
cord-257662-viy65y72	66	25	conditions	condition	NNS
cord-257662-viy65y72	66	26	where	where	WRB
cord-257662-viy65y72	66	27	the	the	DT
cord-257662-viy65y72	66	28	intracellular	intracellular	JJ
cord-257662-viy65y72	66	29	pool	pool	NN
cord-257662-viy65y72	66	30	of	of	IN
cord-257662-viy65y72	66	31	deoxynucleotides	deoxynucleotide	NNS
cord-257662-viy65y72	66	32	is	be	VBZ
cord-257662-viy65y72	66	33	limited	limit	VBN
cord-257662-viy65y72	66	34	(	(	-LRB-
cord-257662-viy65y72	66	35	89	89	CD
cord-257662-viy65y72	66	36	,	,	,
cord-257662-viy65y72	66	37	90	90	CD
cord-257662-viy65y72	66	38	)	)	-RRB-
cord-257662-viy65y72	66	39	.	.	.
cord-257662-viy65y72	67	1	Thus	thus	RB
cord-257662-viy65y72	67	2	,	,	,
cord-257662-viy65y72	67	3	by	by	IN
cord-257662-viy65y72	67	4	inactivating	inactivate	VBG
cord-257662-viy65y72	67	5	this	this	DT
cord-257662-viy65y72	67	6	cellular	cellular	JJ
cord-257662-viy65y72	67	7	and/or	and/or	CC
cord-257662-viy65y72	67	8	viral	viral	JJ
cord-257662-viy65y72	67	9	enzyme	enzyme	NN
cord-257662-viy65y72	67	10	,	,	,
cord-257662-viy65y72	67	11	NO	NO	NNP
cord-257662-viy65y72	67	12	may	may	MD
cord-257662-viy65y72	67	13	halt	halt	VB
cord-257662-viy65y72	67	14	virus	virus	NN
cord-257662-viy65y72	67	15	replication	replication	NN
cord-257662-viy65y72	67	16	by	by	IN
cord-257662-viy65y72	67	17	directly	directly	RB
cord-257662-viy65y72	67	18	inhibiting	inhibit	VBG
cord-257662-viy65y72	67	19	viral	viral	JJ
cord-257662-viy65y72	67	20	DNA	dna	NN
cord-257662-viy65y72	67	21	synthesis	synthesis	NN
cord-257662-viy65y72	67	22	.	.	.
cord-257662-viy65y72	68	1	In	in	IN
cord-257662-viy65y72	68	2	addition	addition	NN
cord-257662-viy65y72	68	3	to	to	IN
cord-257662-viy65y72	68	4	HSV-1	hsv-1	NN
cord-257662-viy65y72	68	5	,	,	,
cord-257662-viy65y72	68	6	treatment	treatment	NN
cord-257662-viy65y72	68	7	of	of	IN
cord-257662-viy65y72	68	8	primary	primary	JJ
cord-257662-viy65y72	68	9	human	human	JJ
cord-257662-viy65y72	68	10	cells	cell	NNS
cord-257662-viy65y72	68	11	with	with	IN
cord-257662-viy65y72	68	12	an	an	DT
cord-257662-viy65y72	68	13	NO	no	DT
cord-257662-viy65y72	68	14	donor	donor	NN
cord-257662-viy65y72	68	15	following	follow	VBG
cord-257662-viy65y72	68	16	infection	infection	NN
cord-257662-viy65y72	68	17	with	with	IN
cord-257662-viy65y72	68	18	human	human	JJ
cord-257662-viy65y72	68	19	cytomegalovirus	cytomegalovirus	NN
cord-257662-viy65y72	68	20	(	(	-LRB-
cord-257662-viy65y72	68	21	HCMV	HCMV	NNP
cord-257662-viy65y72	68	22	)	)	-RRB-
cord-257662-viy65y72	68	23	,	,	,
cord-257662-viy65y72	68	24	a	a	DT
cord-257662-viy65y72	68	25	beta	beta	NN
cord-257662-viy65y72	68	26	-	-	HYPH
cord-257662-viy65y72	68	27	herpesvirus	herpesvirus	NN
cord-257662-viy65y72	68	28	,	,	,
cord-257662-viy65y72	68	29	resulted	result	VBD
cord-257662-viy65y72	68	30	in	in	IN
cord-257662-viy65y72	68	31	a	a	DT
cord-257662-viy65y72	68	32	significant	significant	JJ
cord-257662-viy65y72	68	33	reduction	reduction	NN
cord-257662-viy65y72	68	34	of	of	IN
cord-257662-viy65y72	68	35	early	early	JJ
cord-257662-viy65y72	68	36	and	and	CC
cord-257662-viy65y72	68	37	late	late	JJ
cord-257662-viy65y72	68	38	viral	viral	JJ
cord-257662-viy65y72	68	39	protein	protein	NN
cord-257662-viy65y72	68	40	expression	expression	NN
cord-257662-viy65y72	68	41	(	(	-LRB-
cord-257662-viy65y72	68	42	28	28	CD
cord-257662-viy65y72	68	43	)	)	-RRB-
cord-257662-viy65y72	68	44	.	.	.
cord-257662-viy65y72	69	1	Consistent	consistent	JJ
cord-257662-viy65y72	69	2	with	with	IN
cord-257662-viy65y72	69	3	these	these	DT
cord-257662-viy65y72	69	4	in	in	FW
cord-257662-viy65y72	69	5	vitro	vitro	FW
cord-257662-viy65y72	69	6	data	datum	NNS
cord-257662-viy65y72	69	7	,	,	,
cord-257662-viy65y72	69	8	Nos2	Nos2	NNP
cord-257662-viy65y72	69	9	−/−	−/−	NNP
cord-257662-viy65y72	69	10	mice	mouse	NNS
cord-257662-viy65y72	69	11	(	(	-LRB-
cord-257662-viy65y72	69	12	129	129	CD
cord-257662-viy65y72	69	13	/	/	SYM
cord-257662-viy65y72	69	14	Sv	Sv	NNP
cord-257662-viy65y72	69	15	/	/	SYM
cord-257662-viy65y72	69	16	Ev	Ev	NNP
cord-257662-viy65y72	69	17	x	x	NNP
cord-257662-viy65y72	69	18	C57BL/6	C57BL/6	NNP
cord-257662-viy65y72	69	19	F1	F1	NNP
cord-257662-viy65y72	69	20	)	)	-RRB-
cord-257662-viy65y72	69	21	exhibited	exhibit	VBD
cord-257662-viy65y72	69	22	increased	increase	VBN
cord-257662-viy65y72	69	23	viral	viral	JJ
cord-257662-viy65y72	69	24	titers	titer	NNS
cord-257662-viy65y72	69	25	and	and	CC
cord-257662-viy65y72	69	26	mortality	mortality	NN
cord-257662-viy65y72	69	27	following	follow	VBG
cord-257662-viy65y72	69	28	infection	infection	NN
cord-257662-viy65y72	69	29	with	with	IN
cord-257662-viy65y72	69	30	murine	murine	JJ
cord-257662-viy65y72	69	31	CMV	CMV	NNP
cord-257662-viy65y72	69	32	(	(	-LRB-
cord-257662-viy65y72	69	33	MCMV	MCMV	NNP
cord-257662-viy65y72	69	34	;	;	:
cord-257662-viy65y72	69	35	Smith	Smith	NNP
cord-257662-viy65y72	69	36	VR194	VR194	NNP
cord-257662-viy65y72	69	37	strain	strain	NN
cord-257662-viy65y72	69	38	)	)	-RRB-
cord-257662-viy65y72	69	39	(	(	-LRB-
cord-257662-viy65y72	69	40	29	29	CD
cord-257662-viy65y72	69	41	)	)	-RRB-
cord-257662-viy65y72	69	42	.	.	.
cord-257662-viy65y72	70	1	Nitric	nitric	NN
cord-257662-viy65y72	70	2	oxide	oxide	NN
cord-257662-viy65y72	70	3	has	have	VBZ
cord-257662-viy65y72	70	4	also	also	RB
cord-257662-viy65y72	70	5	been	be	VBN
cord-257662-viy65y72	70	6	shown	show	VBN
cord-257662-viy65y72	70	7	to	to	TO
cord-257662-viy65y72	70	8	have	have	VB
cord-257662-viy65y72	70	9	antiviral	antiviral	JJ
cord-257662-viy65y72	70	10	properties	property	NNS
cord-257662-viy65y72	70	11	on	on	IN
cord-257662-viy65y72	70	12	a	a	DT
cord-257662-viy65y72	70	13	chicken	chicken	NN
cord-257662-viy65y72	70	14	herpesvirus	herpesvirus	NN
cord-257662-viy65y72	70	15	,	,	,
cord-257662-viy65y72	70	16	Marek	Marek	NNP
cord-257662-viy65y72	70	17	's	's	POS
cord-257662-viy65y72	70	18	disease	disease	NN
cord-257662-viy65y72	70	19	virus	virus	NN
cord-257662-viy65y72	70	20	(	(	-LRB-
cord-257662-viy65y72	70	21	MDV	MDV	NNP
cord-257662-viy65y72	70	22	)	)	-RRB-
cord-257662-viy65y72	70	23	,	,	,
cord-257662-viy65y72	70	24	which	which	WDT
cord-257662-viy65y72	70	25	can	can	MD
cord-257662-viy65y72	70	26	cause	cause	VB
cord-257662-viy65y72	70	27	T	T	NNP
cord-257662-viy65y72	70	28	cell	cell	NN
cord-257662-viy65y72	70	29	lymphomas	lymphoma	NNS
cord-257662-viy65y72	70	30	in	in	IN
cord-257662-viy65y72	70	31	chickens	chicken	NNS
cord-257662-viy65y72	70	32	:	:	:
cord-257662-viy65y72	71	1	Addition	addition	NN
cord-257662-viy65y72	71	2	of	of	IN
cord-257662-viy65y72	71	3	NO	no	RB
cord-257662-viy65y72	71	4	-	-	HYPH
cord-257662-viy65y72	71	5	generating	generate	VBG
cord-257662-viy65y72	71	6	compounds	compound	NNS
cord-257662-viy65y72	71	7	inhibited	inhibit	VBD
cord-257662-viy65y72	71	8	viral	viral	JJ
cord-257662-viy65y72	71	9	replication	replication	NN
cord-257662-viy65y72	71	10	in	in	IN
cord-257662-viy65y72	71	11	chicken	chicken	NN
cord-257662-viy65y72	71	12	fibroblasts	fibroblast	NNS
cord-257662-viy65y72	71	13	(	(	-LRB-
cord-257662-viy65y72	71	14	33	33	CD
cord-257662-viy65y72	71	15	)	)	-RRB-
cord-257662-viy65y72	71	16	.	.	.
cord-257662-viy65y72	72	1	Additionally	additionally	RB
cord-257662-viy65y72	72	2	,	,	,
cord-257662-viy65y72	72	3	the	the	DT
cord-257662-viy65y72	72	4	treatment	treatment	NN
cord-257662-viy65y72	72	5	of	of	IN
cord-257662-viy65y72	72	6	chickens	chicken	NNS
cord-257662-viy65y72	72	7	with	with	IN
cord-257662-viy65y72	72	8	an	an	DT
cord-257662-viy65y72	72	9	inhibitor	inhibitor	NN
cord-257662-viy65y72	72	10	of	of	IN
cord-257662-viy65y72	72	11	iNOS	inos	NN
cord-257662-viy65y72	72	12	increased	increase	VBD
cord-257662-viy65y72	72	13	the	the	DT
cord-257662-viy65y72	72	14	level	level	NN
cord-257662-viy65y72	72	15	of	of	IN
cord-257662-viy65y72	72	16	MDV	MDV	NNP
cord-257662-viy65y72	72	17	replication	replication	NN
cord-257662-viy65y72	72	18	in	in	IN
cord-257662-viy65y72	72	19	vivo	vivo	NNP
cord-257662-viy65y72	72	20	(	(	-LRB-
cord-257662-viy65y72	72	21	34	34	CD
cord-257662-viy65y72	72	22	)	)	-RRB-
cord-257662-viy65y72	72	23	.	.	.
cord-257662-viy65y72	73	1	Further	further	JJ
cord-257662-viy65y72	73	2	studies	study	NNS
cord-257662-viy65y72	73	3	demonstrated	demonstrate	VBD
cord-257662-viy65y72	73	4	that	that	IN
cord-257662-viy65y72	73	5	NO	no	DT
cord-257662-viy65y72	73	6	production	production	NN
cord-257662-viy65y72	73	7	was	be	VBD
cord-257662-viy65y72	73	8	limited	limit	VBN
cord-257662-viy65y72	73	9	to	to	IN
cord-257662-viy65y72	73	10	chickens	chicken	NNS
cord-257662-viy65y72	73	11	that	that	WDT
cord-257662-viy65y72	73	12	were	be	VBD
cord-257662-viy65y72	73	13	genetically	genetically	RB
cord-257662-viy65y72	73	14	resistant	resistant	JJ
cord-257662-viy65y72	73	15	to	to	TO
cord-257662-viy65y72	73	16	tumor	tumor	NN
cord-257662-viy65y72	73	17	development	development	NN
cord-257662-viy65y72	73	18	following	follow	VBG
cord-257662-viy65y72	73	19	MDV	MDV	NNP
cord-257662-viy65y72	73	20	infection	infection	NN
cord-257662-viy65y72	73	21	or	or	CC
cord-257662-viy65y72	73	22	to	to	IN
cord-257662-viy65y72	73	23	chickens	chicken	NNS
cord-257662-viy65y72	73	24	that	that	WDT
cord-257662-viy65y72	73	25	were	be	VBD
cord-257662-viy65y72	73	26	vaccinated	vaccinate	VBN
cord-257662-viy65y72	73	27	before	before	IN
cord-257662-viy65y72	73	28	being	be	VBG
cord-257662-viy65y72	73	29	inoculated	inoculate	VBN
cord-257662-viy65y72	73	30	with	with	IN
cord-257662-viy65y72	73	31	MDV	MDV	NNP
cord-257662-viy65y72	73	32	(	(	-LRB-
cord-257662-viy65y72	73	33	35	35	CD
cord-257662-viy65y72	73	34	)	)	-RRB-
cord-257662-viy65y72	73	35	.	.	.
cord-257662-viy65y72	74	1	Thus	thus	RB
cord-257662-viy65y72	74	2	,	,	,
cord-257662-viy65y72	74	3	NO	no	DT
cord-257662-viy65y72	74	4	appeared	appear	VBD
cord-257662-viy65y72	74	5	to	to	TO
cord-257662-viy65y72	74	6	be	be	VB
cord-257662-viy65y72	74	7	produced	produce	VBN
cord-257662-viy65y72	74	8	in	in	IN
cord-257662-viy65y72	74	9	both	both	DT
cord-257662-viy65y72	74	10	types	type	NNS
cord-257662-viy65y72	74	11	of	of	IN
cord-257662-viy65y72	74	12	resistance	resistance	NN
cord-257662-viy65y72	74	13	to	to	TO
cord-257662-viy65y72	74	14	tumor	tumor	NN
cord-257662-viy65y72	74	15	development	development	NN
cord-257662-viy65y72	74	16	in	in	IN
cord-257662-viy65y72	74	17	Marek	Marek	NNP
cord-257662-viy65y72	74	18	's	's	POS
cord-257662-viy65y72	74	19	disease	disease	NN
cord-257662-viy65y72	74	20	,	,	,
cord-257662-viy65y72	74	21	either	either	CC
cord-257662-viy65y72	74	22	acquired	acquire	VBN
cord-257662-viy65y72	74	23	after	after	IN
cord-257662-viy65y72	74	24	vaccination	vaccination	NN
cord-257662-viy65y72	74	25	or	or	CC
cord-257662-viy65y72	74	26	genetic	genetic	JJ
cord-257662-viy65y72	74	27	.	.	.
cord-257662-viy65y72	75	1	Together	together	RB
cord-257662-viy65y72	75	2	,	,	,
cord-257662-viy65y72	75	3	these	these	DT
cord-257662-viy65y72	75	4	findings	finding	NNS
cord-257662-viy65y72	75	5	suggest	suggest	VBP
cord-257662-viy65y72	75	6	a	a	DT
cord-257662-viy65y72	75	7	role	role	NN
cord-257662-viy65y72	75	8	of	of	IN
cord-257662-viy65y72	75	9	NO	no	RB
cord-257662-viy65y72	75	10	in	in	IN
cord-257662-viy65y72	75	11	the	the	DT
cord-257662-viy65y72	75	12	protective	protective	JJ
cord-257662-viy65y72	75	13	immune	immune	JJ
cord-257662-viy65y72	75	14	mechanisms	mechanism	NNS
cord-257662-viy65y72	75	15	against	against	IN
cord-257662-viy65y72	75	16	Marek	Marek	NNP
cord-257662-viy65y72	75	17	's	's	POS
cord-257662-viy65y72	75	18	disease	disease	NN
cord-257662-viy65y72	75	19	,	,	,
cord-257662-viy65y72	75	20	possibly	possibly	RB
cord-257662-viy65y72	75	21	through	through	IN
cord-257662-viy65y72	75	22	its	-PRON-	PRP$
cord-257662-viy65y72	75	23	activity	activity	NN
cord-257662-viy65y72	75	24	on	on	IN
cord-257662-viy65y72	75	25	viral	viral	JJ
cord-257662-viy65y72	75	26	replication	replication	NN
cord-257662-viy65y72	75	27	.	.	.
cord-257662-viy65y72	76	1	Finally	finally	RB
cord-257662-viy65y72	76	2	,	,	,
cord-257662-viy65y72	76	3	studies	study	NNS
cord-257662-viy65y72	76	4	with	with	IN
cord-257662-viy65y72	76	5	HBV	HBV	NNP
cord-257662-viy65y72	76	6	,	,	,
cord-257662-viy65y72	76	7	a	a	DT
cord-257662-viy65y72	76	8	hepadnavirus	hepadnavirus	NN
cord-257662-viy65y72	76	9	associated	associate	VBN
cord-257662-viy65y72	76	10	with	with	IN
cord-257662-viy65y72	76	11	acute	acute	JJ
cord-257662-viy65y72	76	12	and	and	CC
cord-257662-viy65y72	76	13	chronic	chronic	JJ
cord-257662-viy65y72	76	14	hepatitis	hepatitis	NN
cord-257662-viy65y72	76	15	,	,	,
cord-257662-viy65y72	76	16	demonstrated	demonstrate	VBD
cord-257662-viy65y72	76	17	that	that	IN
cord-257662-viy65y72	76	18	HBV	HBV	NNP
cord-257662-viy65y72	76	19	replicated	replicate	VBD
cord-257662-viy65y72	76	20	to	to	IN
cord-257662-viy65y72	76	21	higher	high	JJR
cord-257662-viy65y72	76	22	levels	level	NNS
cord-257662-viy65y72	76	23	in	in	IN
cord-257662-viy65y72	76	24	the	the	DT
cord-257662-viy65y72	76	25	livers	liver	NNS
cord-257662-viy65y72	76	26	of	of	IN
cord-257662-viy65y72	76	27	HBV	HBV	NNP
cord-257662-viy65y72	76	28	-	-	HYPH
cord-257662-viy65y72	76	29	transgenic	transgenic	JJ
cord-257662-viy65y72	76	30	Nos2	Nos2	NNP
cord-257662-viy65y72	76	31	−/−	−/−	NNP
cord-257662-viy65y72	76	32	mice	mouse	NNS
cord-257662-viy65y72	76	33	than	than	IN
cord-257662-viy65y72	76	34	control	control	VB
cord-257662-viy65y72	76	35	transgenic	transgenic	JJ
cord-257662-viy65y72	76	36	mice	mouse	NNS
cord-257662-viy65y72	76	37	,	,	,
cord-257662-viy65y72	76	38	and	and	CC
cord-257662-viy65y72	76	39	transgenic	transgenic	JJ
cord-257662-viy65y72	76	40	Nos2	Nos2	NNP
cord-257662-viy65y72	77	1	−/−	−/−	NNP
cord-257662-viy65y72	78	1	mice	mouse	NNS
cord-257662-viy65y72	78	2	had	have	VBD
cord-257662-viy65y72	78	3	increased	increase	VBN
cord-257662-viy65y72	78	4	Frontiers	Frontiers	NNPS
cord-257662-viy65y72	78	5	in	in	IN
cord-257662-viy65y72	78	6	Immunology	Immunology	NNP
cord-257662-viy65y72	78	7	|	|	NNP
cord-257662-viy65y72	79	1	Antigen	Antigen	NNP
cord-257662-viy65y72	79	2	Presenting	present	VBG
cord-257662-viy65y72	79	3	Cell	cell	NN
cord-257662-viy65y72	79	4	Biology	biology	NN
cord-257662-viy65y72	79	5	liver	liver	NN
cord-257662-viy65y72	79	6	disease	disease	NN
cord-257662-viy65y72	79	7	(	(	-LRB-
cord-257662-viy65y72	79	8	36	36	CD
cord-257662-viy65y72	79	9	)	)	-RRB-
cord-257662-viy65y72	79	10	.	.	.
cord-257662-viy65y72	80	1	It	-PRON-	PRP
cord-257662-viy65y72	80	2	was	be	VBD
cord-257662-viy65y72	80	3	further	further	RB
cord-257662-viy65y72	80	4	demonstrated	demonstrate	VBN
cord-257662-viy65y72	80	5	that	that	IN
cord-257662-viy65y72	80	6	NO	no	DT
cord-257662-viy65y72	80	7	production	production	NN
cord-257662-viy65y72	80	8	by	by	IN
cord-257662-viy65y72	80	9	mononuclear	mononuclear	JJ
cord-257662-viy65y72	80	10	cells	cell	NNS
cord-257662-viy65y72	80	11	,	,	,
cord-257662-viy65y72	80	12	most	most	RBS
cord-257662-viy65y72	80	13	likely	likely	JJ
cord-257662-viy65y72	80	14	macrophages	macrophage	NNS
cord-257662-viy65y72	80	15	,	,	,
cord-257662-viy65y72	80	16	in	in	IN
cord-257662-viy65y72	80	17	the	the	DT
cord-257662-viy65y72	80	18	liver	liver	NN
cord-257662-viy65y72	80	19	mediated	mediate	VBD
cord-257662-viy65y72	80	20	most	most	JJS
cord-257662-viy65y72	80	21	of	of	IN
cord-257662-viy65y72	80	22	the	the	DT
cord-257662-viy65y72	80	23	antiviral	antiviral	JJ
cord-257662-viy65y72	80	24	activity	activity	NN
cord-257662-viy65y72	80	25	resulting	result	VBG
cord-257662-viy65y72	80	26	from	from	IN
cord-257662-viy65y72	80	27	IFN	IFN	NNP
cord-257662-viy65y72	80	28	-	-	HYPH
cord-257662-viy65y72	80	29	γ	γ	NN
cord-257662-viy65y72	80	30	production	production	NN
cord-257662-viy65y72	80	31	by	by	IN
cord-257662-viy65y72	80	32	virus	virus	NN
cord-257662-viy65y72	80	33	-	-	HYPH
cord-257662-viy65y72	80	34	specific	specific	JJ
cord-257662-viy65y72	80	35	T	t	NN
cord-257662-viy65y72	80	36	cells	cell	NNS
cord-257662-viy65y72	80	37	(	(	-LRB-
cord-257662-viy65y72	80	38	36	36	CD
cord-257662-viy65y72	80	39	)	)	-RRB-
cord-257662-viy65y72	80	40	,	,	,
cord-257662-viy65y72	80	41	suggesting	suggest	VBG
cord-257662-viy65y72	80	42	an	an	DT
cord-257662-viy65y72	80	43	antiviral	antiviral	JJ
cord-257662-viy65y72	80	44	role	role	NN
cord-257662-viy65y72	80	45	for	for	IN
cord-257662-viy65y72	80	46	macrophage	macrophage	NN
cord-257662-viy65y72	80	47	-	-	HYPH
cord-257662-viy65y72	80	48	derived	derive	VBN
cord-257662-viy65y72	80	49	NO	no	DT
cord-257662-viy65y72	80	50	following	follow	VBG
cord-257662-viy65y72	80	51	HBV	HBV	NNP
cord-257662-viy65y72	80	52	infection	infection	NN
cord-257662-viy65y72	80	53	in	in	IN
cord-257662-viy65y72	80	54	mice	mouse	NNS
cord-257662-viy65y72	80	55	.	.	.
cord-257662-viy65y72	81	1	In	in	IN
cord-257662-viy65y72	81	2	addition	addition	NN
cord-257662-viy65y72	81	3	to	to	IN
cord-257662-viy65y72	81	4	DNA	dna	NN
cord-257662-viy65y72	81	5	viruses	virus	NNS
cord-257662-viy65y72	81	6	,	,	,
cord-257662-viy65y72	81	7	macrophage	macrophage	NN
cord-257662-viy65y72	81	8	-	-	HYPH
cord-257662-viy65y72	81	9	derived	derive	VBN
cord-257662-viy65y72	81	10	NO	no	RB
cord-257662-viy65y72	81	11	also	also	RB
cord-257662-viy65y72	81	12	exerts	exert	VBZ
cord-257662-viy65y72	81	13	antiviral	antiviral	JJ
cord-257662-viy65y72	81	14	effects	effect	NNS
cord-257662-viy65y72	81	15	against	against	IN
cord-257662-viy65y72	81	16	a	a	DT
cord-257662-viy65y72	81	17	number	number	NN
cord-257662-viy65y72	81	18	of	of	IN
cord-257662-viy65y72	81	19	RNA	RNA	NNP
cord-257662-viy65y72	81	20	viruses	virus	NNS
cord-257662-viy65y72	81	21	.	.	.
cord-257662-viy65y72	82	1	Inhibition	inhibition	NN
cord-257662-viy65y72	82	2	of	of	IN
cord-257662-viy65y72	82	3	JEV	JEV	NNP
cord-257662-viy65y72	82	4	,	,	,
cord-257662-viy65y72	82	5	a	a	DT
cord-257662-viy65y72	82	6	mosquito	mosquito	NN
cord-257662-viy65y72	82	7	-	-	HYPH
cord-257662-viy65y72	82	8	transmitted	transmit	VBN
cord-257662-viy65y72	82	9	flavivirus	flavivirus	NNP
cord-257662-viy65y72	82	10	that	that	WDT
cord-257662-viy65y72	82	11	causes	cause	VBZ
cord-257662-viy65y72	82	12	encephalitis	encephalitis	JJ
cord-257662-viy65y72	82	13	in	in	IN
cord-257662-viy65y72	82	14	humans	human	NNS
cord-257662-viy65y72	82	15	,	,	,
cord-257662-viy65y72	82	16	in	in	IN
cord-257662-viy65y72	82	17	IFN	IFN	NNP
cord-257662-viy65y72	82	18	-	-	HYPH
cord-257662-viy65y72	82	19	γ	γ	NNP
cord-257662-viy65y72	82	20	-	-	HYPH
cord-257662-viy65y72	82	21	activated	activate	VBN
cord-257662-viy65y72	82	22	RAW	raw	JJ
cord-257662-viy65y72	82	23	264.7	264.7	CD
cord-257662-viy65y72	82	24	macrophages	macrophage	NNS
cord-257662-viy65y72	82	25	in	in	IN
cord-257662-viy65y72	82	26	vitro	vitro	FW
cord-257662-viy65y72	82	27	correlated	correlate	VBN
cord-257662-viy65y72	82	28	with	with	IN
cord-257662-viy65y72	82	29	NO	no	DT
cord-257662-viy65y72	82	30	production	production	NN
cord-257662-viy65y72	82	31	,	,	,
cord-257662-viy65y72	82	32	and	and	CC
cord-257662-viy65y72	82	33	IFN	IFN	NNP
cord-257662-viy65y72	82	34	-	-	HYPH
cord-257662-viy65y72	82	35	γ	γ	NNP
cord-257662-viy65y72	82	36	-	-	HYPH
cord-257662-viy65y72	82	37	activated	activate	VBN
cord-257662-viy65y72	82	38	RAW	raw	JJ
cord-257662-viy65y72	82	39	264.7	264.7	CD
cord-257662-viy65y72	82	40	macrophage	macrophage	NN
cord-257662-viy65y72	82	41	-	-	HYPH
cord-257662-viy65y72	82	42	mediated	mediate	VBN
cord-257662-viy65y72	82	43	inhibition	inhibition	NN
cord-257662-viy65y72	82	44	of	of	IN
cord-257662-viy65y72	82	45	JEV	JEV	NNP
cord-257662-viy65y72	82	46	replication	replication	NN
cord-257662-viy65y72	82	47	in	in	IN
cord-257662-viy65y72	82	48	murine	murine	JJ
cord-257662-viy65y72	82	49	neuroblastoma	neuroblastoma	NN
cord-257662-viy65y72	82	50	N18	N18	NNP
cord-257662-viy65y72	82	51	cells	cell	NNS
cord-257662-viy65y72	82	52	was	be	VBD
cord-257662-viy65y72	82	53	NO	no	RB
cord-257662-viy65y72	82	54	-	-	HYPH
cord-257662-viy65y72	82	55	dependent	dependent	JJ
cord-257662-viy65y72	82	56	(	(	-LRB-
cord-257662-viy65y72	82	57	12	12	CD
cord-257662-viy65y72	82	58	)	)	-RRB-
cord-257662-viy65y72	82	59	.	.	.
cord-257662-viy65y72	83	1	Moreover	moreover	RB
cord-257662-viy65y72	83	2	,	,	,
cord-257662-viy65y72	83	3	inhibition	inhibition	NN
cord-257662-viy65y72	83	4	of	of	IN
cord-257662-viy65y72	83	5	NOS	NOS	NNP
cord-257662-viy65y72	83	6	activity	activity	NN
cord-257662-viy65y72	83	7	led	lead	VBD
cord-257662-viy65y72	83	8	to	to	IN
cord-257662-viy65y72	83	9	increased	increase	VBN
cord-257662-viy65y72	83	10	mortality	mortality	NN
cord-257662-viy65y72	83	11	in	in	IN
cord-257662-viy65y72	83	12	JEV	JEV	NNP
cord-257662-viy65y72	83	13	-	-	HYPH
cord-257662-viy65y72	83	14	infected	infect	VBN
cord-257662-viy65y72	83	15	mice	mouse	NNS
cord-257662-viy65y72	83	16	(	(	-LRB-
cord-257662-viy65y72	83	17	12	12	CD
cord-257662-viy65y72	83	18	)	)	-RRB-
cord-257662-viy65y72	83	19	.	.	.
cord-257662-viy65y72	84	1	In	in	IN
cord-257662-viy65y72	84	2	terms	term	NNS
cord-257662-viy65y72	84	3	of	of	IN
cord-257662-viy65y72	84	4	its	-PRON-	PRP$
cord-257662-viy65y72	84	5	mechanism	mechanism	NN
cord-257662-viy65y72	84	6	of	of	IN
cord-257662-viy65y72	84	7	action	action	NN
cord-257662-viy65y72	84	8	,	,	,
cord-257662-viy65y72	84	9	NO	no	UH
cord-257662-viy65y72	84	10	was	be	VBD
cord-257662-viy65y72	84	11	found	find	VBN
cord-257662-viy65y72	84	12	to	to	TO
cord-257662-viy65y72	84	13	inhibit	inhibit	VB
cord-257662-viy65y72	84	14	JEV	JEV	NNP
cord-257662-viy65y72	84	15	RNA	RNA	NNP
cord-257662-viy65y72	84	16	synthesis	synthesis	NN
cord-257662-viy65y72	84	17	,	,	,
cord-257662-viy65y72	84	18	viral	viral	JJ
cord-257662-viy65y72	84	19	protein	protein	NN
cord-257662-viy65y72	84	20	accumulation	accumulation	NN
cord-257662-viy65y72	84	21	,	,	,
cord-257662-viy65y72	84	22	and	and	CC
cord-257662-viy65y72	84	23	virus	virus	NN
cord-257662-viy65y72	84	24	release	release	NN
cord-257662-viy65y72	84	25	from	from	IN
cord-257662-viy65y72	84	26	infected	infected	JJ
cord-257662-viy65y72	84	27	cells	cell	NNS
cord-257662-viy65y72	84	28	in	in	IN
cord-257662-viy65y72	84	29	vitro	vitro	FW
cord-257662-viy65y72	84	30	(	(	-LRB-
cord-257662-viy65y72	84	31	12	12	CD
cord-257662-viy65y72	84	32	)	)	-RRB-
cord-257662-viy65y72	84	33	.	.	.
cord-257662-viy65y72	85	1	These	these	DT
cord-257662-viy65y72	85	2	data	datum	NNS
cord-257662-viy65y72	85	3	suggest	suggest	VBP
cord-257662-viy65y72	85	4	that	that	IN
cord-257662-viy65y72	85	5	NO	NO	NNP
cord-257662-viy65y72	85	6	may	may	MD
cord-257662-viy65y72	85	7	be	be	VB
cord-257662-viy65y72	85	8	directly	directly	RB
cord-257662-viy65y72	85	9	or	or	CC
cord-257662-viy65y72	85	10	indirectly	indirectly	RB
cord-257662-viy65y72	85	11	inhibiting	inhibit	VBG
cord-257662-viy65y72	85	12	viral	viral	JJ
cord-257662-viy65y72	85	13	enzymes	enzyme	NNS
cord-257662-viy65y72	85	14	and/or	and/or	CC
cord-257662-viy65y72	85	15	other	other	JJ
cord-257662-viy65y72	85	16	www.frontiersin.org	www.frontiersin.org	IN
cord-257662-viy65y72	85	17	cellular	cellular	JJ
cord-257662-viy65y72	85	18	components	component	NNS
cord-257662-viy65y72	85	19	required	require	VBN
cord-257662-viy65y72	85	20	for	for	IN
cord-257662-viy65y72	85	21	viral	viral	JJ
cord-257662-viy65y72	85	22	replication	replication	NN
cord-257662-viy65y72	85	23	,	,	,
cord-257662-viy65y72	85	24	and	and	CC
cord-257662-viy65y72	85	25	this	this	DT
cord-257662-viy65y72	85	26	may	may	MD
cord-257662-viy65y72	85	27	subsequently	subsequently	RB
cord-257662-viy65y72	85	28	block	block	VB
cord-257662-viy65y72	85	29	viral	viral	JJ
cord-257662-viy65y72	85	30	protein	protein	NN
cord-257662-viy65y72	85	31	synthesis	synthesis	NN
cord-257662-viy65y72	85	32	.	.	.
cord-257662-viy65y72	86	1	Additionally	additionally	RB
cord-257662-viy65y72	86	2	,	,	,
cord-257662-viy65y72	86	3	NO	NO	NNP
cord-257662-viy65y72	86	4	may	may	MD
cord-257662-viy65y72	86	5	interfere	interfere	VB
cord-257662-viy65y72	86	6	with	with	IN
cord-257662-viy65y72	86	7	the	the	DT
cord-257662-viy65y72	86	8	release	release	NN
cord-257662-viy65y72	86	9	and/or	and/or	CC
cord-257662-viy65y72	86	10	maturation	maturation	NN
cord-257662-viy65y72	86	11	of	of	IN
cord-257662-viy65y72	86	12	virions	virion	NNS
cord-257662-viy65y72	86	13	.	.	.
cord-257662-viy65y72	87	1	Monocyte	Monocyte	NNP
cord-257662-viy65y72	87	2	/	/	SYM
cord-257662-viy65y72	87	3	macrophage	macrophage	NN
cord-257662-viy65y72	87	4	-	-	HYPH
cord-257662-viy65y72	87	5	derived	derive	VBN
cord-257662-viy65y72	88	1	NO	no	UH
cord-257662-viy65y72	88	2	may	may	MD
cord-257662-viy65y72	88	3	also	also	RB
cord-257662-viy65y72	88	4	block	block	VB
cord-257662-viy65y72	88	5	replication	replication	NN
cord-257662-viy65y72	88	6	of	of	IN
cord-257662-viy65y72	88	7	DENV	DENV	NNP
cord-257662-viy65y72	88	8	,	,	,
cord-257662-viy65y72	88	9	another	another	DT
cord-257662-viy65y72	88	10	mosquito	mosquito	NN
cord-257662-viy65y72	88	11	-	-	HYPH
cord-257662-viy65y72	88	12	transmitted	transmit	VBN
cord-257662-viy65y72	88	13	flavivirus	flavivirus	NNP
cord-257662-viy65y72	88	14	.	.	.
cord-257662-viy65y72	89	1	Infection	infection	NN
cord-257662-viy65y72	89	2	with	with	IN
cord-257662-viy65y72	89	3	DENV	DENV	NNP
cord-257662-viy65y72	89	4	resulted	result	VBD
cord-257662-viy65y72	89	5	in	in	IN
cord-257662-viy65y72	89	6	increased	increase	VBN
cord-257662-viy65y72	89	7	levels	level	NNS
cord-257662-viy65y72	89	8	of	of	IN
cord-257662-viy65y72	89	9	NO	no	DT
cord-257662-viy65y72	89	10	in	in	IN
cord-257662-viy65y72	89	11	patients	patient	NNS
cord-257662-viy65y72	89	12	with	with	IN
cord-257662-viy65y72	89	13	dengue	dengue	NN
cord-257662-viy65y72	89	14	fever	fever	NN
cord-257662-viy65y72	89	15	,	,	,
cord-257662-viy65y72	89	16	the	the	DT
cord-257662-viy65y72	89	17	classic	classic	JJ
cord-257662-viy65y72	89	18	form	form	NN
cord-257662-viy65y72	89	19	of	of	IN
cord-257662-viy65y72	89	20	the	the	DT
cord-257662-viy65y72	89	21	disease	disease	NN
cord-257662-viy65y72	89	22	(	(	-LRB-
cord-257662-viy65y72	89	23	37	37	CD
cord-257662-viy65y72	89	24	)	)	-RRB-
cord-257662-viy65y72	89	25	.	.	.
cord-257662-viy65y72	90	1	Additionally	additionally	RB
cord-257662-viy65y72	90	2	,	,	,
cord-257662-viy65y72	90	3	iNOS	inos	JJ
cord-257662-viy65y72	90	4	expression	expression	NN
cord-257662-viy65y72	90	5	was	be	VBD
cord-257662-viy65y72	90	6	induced	induce	VBN
cord-257662-viy65y72	90	7	in	in	IN
cord-257662-viy65y72	90	8	CD14	CD14	NNP
cord-257662-viy65y72	90	9	+	+	CC
cord-257662-viy65y72	90	10	monocytes	monocyte	NNS
cord-257662-viy65y72	90	11	from	from	IN
cord-257662-viy65y72	90	12	a	a	DT
cord-257662-viy65y72	90	13	subset	subset	NN
cord-257662-viy65y72	90	14	of	of	IN
cord-257662-viy65y72	90	15	acutely	acutely	RB
cord-257662-viy65y72	90	16	infected	infect	VBN
cord-257662-viy65y72	90	17	individuals	individual	NNS
cord-257662-viy65y72	90	18	(	(	-LRB-
cord-257662-viy65y72	90	19	13	13	CD
cord-257662-viy65y72	90	20	)	)	-RRB-
cord-257662-viy65y72	90	21	.	.	.
cord-257662-viy65y72	91	1	It	-PRON-	PRP
cord-257662-viy65y72	91	2	was	be	VBD
cord-257662-viy65y72	91	3	further	further	RB
cord-257662-viy65y72	91	4	shown	show	VBN
cord-257662-viy65y72	91	5	that	that	IN
cord-257662-viy65y72	91	6	ex	ex	FW
cord-257662-viy65y72	91	7	vivo	vivo	NN
cord-257662-viy65y72	91	8	infection	infection	NN
cord-257662-viy65y72	91	9	of	of	IN
cord-257662-viy65y72	91	10	human	human	JJ
cord-257662-viy65y72	91	11	monocytes	monocyte	NNS
cord-257662-viy65y72	91	12	with	with	IN
cord-257662-viy65y72	91	13	DENV-1	DENV-1	NNS
cord-257662-viy65y72	91	14	resulted	result	VBD
cord-257662-viy65y72	91	15	in	in	IN
cord-257662-viy65y72	91	16	increased	increase	VBN
cord-257662-viy65y72	91	17	iNOS	inos	JJ
cord-257662-viy65y72	91	18	expression	expression	NN
cord-257662-viy65y72	91	19	,	,	,
cord-257662-viy65y72	91	20	and	and	CC
cord-257662-viy65y72	91	21	inhibition	inhibition	NN
cord-257662-viy65y72	91	22	of	of	IN
cord-257662-viy65y72	91	23	iNOS	inos	JJ
cord-257662-viy65y72	91	24	activity	activity	NN
cord-257662-viy65y72	91	25	led	lead	VBN
cord-257662-viy65y72	91	26	to	to	IN
cord-257662-viy65y72	91	27	increased	increase	VBN
cord-257662-viy65y72	91	28	DENV	DENV	NNP
cord-257662-viy65y72	91	29	antigen	antigen	NN
cord-257662-viy65y72	91	30	detection	detection	NN
cord-257662-viy65y72	91	31	in	in	IN
cord-257662-viy65y72	91	32	these	these	DT
cord-257662-viy65y72	91	33	cells	cell	NNS
cord-257662-viy65y72	91	34	(	(	-LRB-
cord-257662-viy65y72	91	35	13	13	CD
cord-257662-viy65y72	91	36	)	)	-RRB-
cord-257662-viy65y72	91	37	.	.	.
cord-257662-viy65y72	92	1	Moreover	moreover	RB
cord-257662-viy65y72	92	2	,	,	,
cord-257662-viy65y72	92	3	treatment	treatment	NN
cord-257662-viy65y72	92	4	of	of	IN
cord-257662-viy65y72	92	5	C6/36	C6/36	NNP
cord-257662-viy65y72	92	6	mosquito	mosquito	NN
cord-257662-viy65y72	92	7	cells	cell	NNS
cord-257662-viy65y72	92	8	with	with	IN
cord-257662-viy65y72	92	9	an	an	DT
cord-257662-viy65y72	92	10	NO	no	DT
cord-257662-viy65y72	92	11	donor	donor	NN
cord-257662-viy65y72	92	12	resulted	result	VBD
cord-257662-viy65y72	92	13	in	in	IN
cord-257662-viy65y72	92	14	reduced	reduce	VBN
cord-257662-viy65y72	92	15	DENV	denv	NN
cord-257662-viy65y72	92	16	-	-	HYPH
cord-257662-viy65y72	92	17	positive	positive	JJ
cord-257662-viy65y72	92	18	cells	cell	NNS
cord-257662-viy65y72	92	19	(	(	-LRB-
cord-257662-viy65y72	92	20	13	13	CD
cord-257662-viy65y72	92	21	)	)	-RRB-
cord-257662-viy65y72	92	22	.	.	.
cord-257662-viy65y72	93	1	These	these	DT
cord-257662-viy65y72	93	2	data	datum	NNS
cord-257662-viy65y72	93	3	suggest	suggest	VBP
cord-257662-viy65y72	93	4	that	that	IN
cord-257662-viy65y72	93	5	DENV	DENV	NNP
cord-257662-viy65y72	93	6	replication	replication	NN
cord-257662-viy65y72	93	7	is	be	VBZ
cord-257662-viy65y72	93	8	susceptible	susceptible	JJ
cord-257662-viy65y72	93	9	to	to	IN
cord-257662-viy65y72	93	10	NO	no	RB
cord-257662-viy65y72	93	11	-	-	HYPH
cord-257662-viy65y72	93	12	mediated	mediate	VBN
cord-257662-viy65y72	93	13	inhibition	inhibition	NN
cord-257662-viy65y72	93	14	.	.	.
cord-257662-viy65y72	94	1	Consistent	consistent	JJ
cord-257662-viy65y72	94	2	with	with	IN
cord-257662-viy65y72	94	3	this	this	DT
cord-257662-viy65y72	94	4	,	,	,
cord-257662-viy65y72	94	5	Nos2	Nos2	NNP
cord-257662-viy65y72	94	6	−/−	−/−	NNP
cord-257662-viy65y72	94	7	mice	mouse	NNS
cord-257662-viy65y72	94	8	were	be	VBD
cord-257662-viy65y72	94	9	shown	show	VBN
cord-257662-viy65y72	94	10	to	to	TO
cord-257662-viy65y72	94	11	be	be	VB
cord-257662-viy65y72	94	12	more	more	RBR
cord-257662-viy65y72	94	13	susceptible	susceptible	JJ
cord-257662-viy65y72	94	14	to	to	IN
cord-257662-viy65y72	94	15	DENV	DENV	NNP
cord-257662-viy65y72	94	16	infection	infection	NN
cord-257662-viy65y72	94	17	,	,	,
cord-257662-viy65y72	94	18	resulting	result	VBG
cord-257662-viy65y72	94	19	in	in	IN
cord-257662-viy65y72	94	20	more	more	RBR
cord-257662-viy65y72	94	21	severe	severe	JJ
cord-257662-viy65y72	94	22	disease	disease	NN
cord-257662-viy65y72	94	23	and	and	CC
cord-257662-viy65y72	94	24	increased	increase	VBN
cord-257662-viy65y72	94	25	lethality	lethality	NN
cord-257662-viy65y72	94	26	in	in	IN
cord-257662-viy65y72	94	27	mouse	mouse	NN
cord-257662-viy65y72	94	28	models	model	NNS
cord-257662-viy65y72	94	29	of	of	IN
cord-257662-viy65y72	94	30	DENV-2	DENV-2	NNP
cord-257662-viy65y72	94	31	and	and	CC
cord-257662-viy65y72	94	32	DENV-3	denv-3	NN
cord-257662-viy65y72	94	33	infection	infection	NN
cord-257662-viy65y72	94	34	(	(	-LRB-
cord-257662-viy65y72	94	35	38	38	CD
cord-257662-viy65y72	94	36	,	,	,
cord-257662-viy65y72	94	37	39	39	CD
cord-257662-viy65y72	94	38	)	)	-RRB-
cord-257662-viy65y72	94	39	.	.	.
cord-257662-viy65y72	95	1	It	-PRON-	PRP
cord-257662-viy65y72	95	2	was	be	VBD
cord-257662-viy65y72	95	3	further	further	RB
cord-257662-viy65y72	95	4	demonstrated	demonstrate	VBN
cord-257662-viy65y72	95	5	that	that	IN
cord-257662-viy65y72	95	6	,	,	,
cord-257662-viy65y72	95	7	following	follow	VBG
cord-257662-viy65y72	95	8	DENV	DENV	NNP
cord-257662-viy65y72	95	9	infection	infection	NN
cord-257662-viy65y72	95	10	in	in	IN
cord-257662-viy65y72	95	11	vivo	vivo	NN
cord-257662-viy65y72	95	12	,	,	,
cord-257662-viy65y72	95	13	IL-12	IL-12	NNP
cord-257662-viy65y72	95	14	and	and	CC
cord-257662-viy65y72	95	15	IL-18	IL-18	NNP
cord-257662-viy65y72	95	16	induced	induce	VBD
cord-257662-viy65y72	95	17	IFN	IFN	NNP
cord-257662-viy65y72	95	18	-	-	HYPH
cord-257662-viy65y72	95	19	γ	γ	NN
cord-257662-viy65y72	95	20	production	production	NN
cord-257662-viy65y72	95	21	,	,	,
cord-257662-viy65y72	95	22	resulting	result	VBG
cord-257662-viy65y72	95	23	in	in	IN
cord-257662-viy65y72	95	24	iNOS	inos	JJ
cord-257662-viy65y72	95	25	expression	expression	NN
cord-257662-viy65y72	95	26	and	and	CC
cord-257662-viy65y72	95	27	NO	no	DT
cord-257662-viy65y72	95	28	production	production	NN
cord-257662-viy65y72	95	29	,	,	,
cord-257662-viy65y72	95	30	which	which	WDT
cord-257662-viy65y72	95	31	contributed	contribute	VBD
cord-257662-viy65y72	95	32	to	to	IN
cord-257662-viy65y72	95	33	viral	viral	JJ
cord-257662-viy65y72	95	34	control	control	NN
cord-257662-viy65y72	95	35	(	(	-LRB-
cord-257662-viy65y72	95	36	38	38	CD
cord-257662-viy65y72	95	37	,	,	,
cord-257662-viy65y72	95	38	39	39	CD
cord-257662-viy65y72	95	39	)	)	-RRB-
cord-257662-viy65y72	95	40	.	.	.
cord-257662-viy65y72	96	1	In	in	IN
cord-257662-viy65y72	96	2	addition	addition	NN
cord-257662-viy65y72	96	3	to	to	IN
cord-257662-viy65y72	96	4	monocyte	monocyte	NNP
cord-257662-viy65y72	96	5	/	/	SYM
cord-257662-viy65y72	96	6	macrophage	macrophage	NN
cord-257662-viy65y72	96	7	-	-	HYPH
cord-257662-viy65y72	96	8	derived	derive	VBN
cord-257662-viy65y72	96	9	NO	no	NN
cord-257662-viy65y72	96	10	,	,	,
cord-257662-viy65y72	96	11	a	a	DT
cord-257662-viy65y72	96	12	recent	recent	JJ
cord-257662-viy65y72	96	13	study	study	NN
cord-257662-viy65y72	96	14	demonstrated	demonstrate	VBD
cord-257662-viy65y72	96	15	that	that	IN
cord-257662-viy65y72	96	16	platelets	platelet	NNS
cord-257662-viy65y72	96	17	isolated	isolate	VBN
cord-257662-viy65y72	96	18	from	from	IN
cord-257662-viy65y72	96	19	patients	patient	NNS
cord-257662-viy65y72	96	20	with	with	IN
cord-257662-viy65y72	96	21	dengue	dengue	NN
cord-257662-viy65y72	96	22	fever	fever	NN
cord-257662-viy65y72	96	23	had	have	VBD
cord-257662-viy65y72	96	24	increased	increase	VBN
cord-257662-viy65y72	96	25	l	l	NN
cord-257662-viy65y72	96	26	-	-	HYPH
cord-257662-viy65y72	96	27	arginine	arginine	NN
cord-257662-viy65y72	96	28	transport	transport	NN
cord-257662-viy65y72	96	29	and	and	CC
cord-257662-viy65y72	96	30	increased	increase	VBD
cord-257662-viy65y72	96	31	NO	no	DT
cord-257662-viy65y72	96	32	production	production	NN
cord-257662-viy65y72	96	33	compared	compare	VBN
cord-257662-viy65y72	96	34	to	to	IN
cord-257662-viy65y72	96	35	platelets	platelet	NNS
cord-257662-viy65y72	96	36	from	from	IN
cord-257662-viy65y72	96	37	healthy	healthy	JJ
cord-257662-viy65y72	96	38	controls	control	NNS
cord-257662-viy65y72	96	39	(	(	-LRB-
cord-257662-viy65y72	96	40	40	40	CD
cord-257662-viy65y72	96	41	)	)	-RRB-
cord-257662-viy65y72	96	42	.	.	.
cord-257662-viy65y72	97	1	However	however	RB
cord-257662-viy65y72	97	2	,	,	,
cord-257662-viy65y72	97	3	NO	no	RB
cord-257662-viy65y72	97	4	has	have	VBZ
cord-257662-viy65y72	97	5	anti	anti	JJ
cord-257662-viy65y72	97	6	-	-	JJ
cord-257662-viy65y72	97	7	aggregatory	aggregatory	JJ
cord-257662-viy65y72	97	8	properties	property	NNS
cord-257662-viy65y72	97	9	,	,	,
cord-257662-viy65y72	97	10	and	and	CC
cord-257662-viy65y72	97	11	Mendes	Mendes	NNP
cord-257662-viy65y72	97	12	-	-	HYPH
cord-257662-viy65y72	97	13	Ribeiro	Ribeiro	NNP
cord-257662-viy65y72	97	14	et	et	NNP
cord-257662-viy65y72	97	15	al	al	NNP
cord-257662-viy65y72	97	16	.	.	.
cord-257662-viy65y72	98	1	(	(	-LRB-
cord-257662-viy65y72	98	2	40	40	CD
cord-257662-viy65y72	98	3	)	)	-RRB-
cord-257662-viy65y72	98	4	found	find	VBD
cord-257662-viy65y72	98	5	that	that	IN
cord-257662-viy65y72	98	6	dengue	dengue	NN
cord-257662-viy65y72	98	7	patients	patient	NNS
cord-257662-viy65y72	98	8	exhibited	exhibit	VBD
cord-257662-viy65y72	98	9	decreased	decreased	JJ
cord-257662-viy65y72	98	10	collagen	collagen	NN
cord-257662-viy65y72	98	11	-	-	HYPH
cord-257662-viy65y72	98	12	induced	induce	VBN
cord-257662-viy65y72	98	13	platelet	platelet	NN
cord-257662-viy65y72	98	14	aggregation	aggregation	NN
cord-257662-viy65y72	98	15	,	,	,
cord-257662-viy65y72	98	16	consistent	consistent	JJ
cord-257662-viy65y72	98	17	with	with	IN
cord-257662-viy65y72	98	18	the	the	DT
cord-257662-viy65y72	98	19	vascular	vascular	JJ
cord-257662-viy65y72	98	20	leak	leak	NN
cord-257662-viy65y72	98	21	and	and	CC
cord-257662-viy65y72	98	22	hemorrhagic	hemorrhagic	JJ
cord-257662-viy65y72	98	23	manifestations	manifestation	NNS
cord-257662-viy65y72	98	24	of	of	IN
cord-257662-viy65y72	98	25	dengue	dengue	NN
cord-257662-viy65y72	98	26	hemorrhagic	hemorrhagic	JJ
cord-257662-viy65y72	98	27	fever	fever	NN
cord-257662-viy65y72	98	28	/	/	SYM
cord-257662-viy65y72	98	29	dengue	dengue	NN
cord-257662-viy65y72	98	30	shock	shock	NN
cord-257662-viy65y72	98	31	syndrome	syndrome	NN
cord-257662-viy65y72	98	32	(	(	-LRB-
cord-257662-viy65y72	98	33	DHF	DHF	NNP
cord-257662-viy65y72	98	34	/	/	SYM
cord-257662-viy65y72	98	35	DSS	DSS	NNP
cord-257662-viy65y72	98	36	)	)	-RRB-
cord-257662-viy65y72	98	37	,	,	,
cord-257662-viy65y72	98	38	thus	thus	RB
cord-257662-viy65y72	98	39	establishing	establish	VBG
cord-257662-viy65y72	98	40	an	an	DT
cord-257662-viy65y72	98	41	association	association	NN
cord-257662-viy65y72	98	42	between	between	IN
cord-257662-viy65y72	98	43	reduced	reduced	JJ
cord-257662-viy65y72	98	44	platelet	platelet	NN
cord-257662-viy65y72	98	45	aggregation	aggregation	NN
cord-257662-viy65y72	98	46	,	,	,
cord-257662-viy65y72	98	47	enhancement	enhancement	NN
cord-257662-viy65y72	98	48	of	of	IN
cord-257662-viy65y72	98	49	the	the	DT
cord-257662-viy65y72	98	50	l	l	NN
cord-257662-viy65y72	98	51	-	-	HYPH
cord-257662-viy65y72	98	52	arginine	arginine	NN
cord-257662-viy65y72	98	53	-	-	HYPH
cord-257662-viy65y72	98	54	NO	no	NN
cord-257662-viy65y72	98	55	pathway	pathway	NN
cord-257662-viy65y72	98	56	,	,	,
cord-257662-viy65y72	98	57	and	and	CC
cord-257662-viy65y72	98	58	DHF	DHF	NNP
cord-257662-viy65y72	98	59	/	/	SYM
cord-257662-viy65y72	98	60	DSS	DSS	NNP
cord-257662-viy65y72	98	61	(	(	-LRB-
cord-257662-viy65y72	98	62	41	41	CD
cord-257662-viy65y72	98	63	)	)	-RRB-
cord-257662-viy65y72	98	64	.	.	.
cord-257662-viy65y72	99	1	In	in	IN
cord-257662-viy65y72	99	2	contrast	contrast	NN
cord-257662-viy65y72	99	3	,	,	,
cord-257662-viy65y72	99	4	Getts	Getts	NNP
cord-257662-viy65y72	99	5	and	and	CC
cord-257662-viy65y72	99	6	colleagues	colleague	NNS
cord-257662-viy65y72	99	7	showed	show	VBD
cord-257662-viy65y72	99	8	that	that	IN
cord-257662-viy65y72	99	9	experimentally	experimentally	RB
cord-257662-viy65y72	99	10	abrogating	abrogate	VBG
cord-257662-viy65y72	99	11	NO	no	DT
cord-257662-viy65y72	99	12	activity	activity	NN
cord-257662-viy65y72	99	13	during	during	IN
cord-257662-viy65y72	99	14	West	West	NNP
cord-257662-viy65y72	99	15	Nile	Nile	NNP
cord-257662-viy65y72	99	16	virus	virus	NN
cord-257662-viy65y72	99	17	(	(	-LRB-
cord-257662-viy65y72	99	18	WNV	WNV	NNP
cord-257662-viy65y72	99	19	)	)	-RRB-
cord-257662-viy65y72	99	20	encephalitis	encephalitis	RB
cord-257662-viy65y72	99	21	,	,	,
cord-257662-viy65y72	99	22	a	a	DT
cord-257662-viy65y72	99	23	related	relate	VBN
cord-257662-viy65y72	99	24	flavivirus	flavivirus	NN
cord-257662-viy65y72	99	25	,	,	,
cord-257662-viy65y72	99	26	in	in	IN
cord-257662-viy65y72	99	27	NO	no	DT
cord-257662-viy65y72	99	28	-	-	HYPH
cord-257662-viy65y72	99	29	competent	competent	JJ
cord-257662-viy65y72	99	30	mice	mouse	NNS
cord-257662-viy65y72	99	31	at	at	IN
cord-257662-viy65y72	99	32	a	a	DT
cord-257662-viy65y72	99	33	specific	specific	JJ
cord-257662-viy65y72	99	34	,	,	,
cord-257662-viy65y72	99	35	relatively	relatively	RB
cord-257662-viy65y72	99	36	late	late	JJ
cord-257662-viy65y72	99	37	time	time	NN
cord-257662-viy65y72	99	38	point	point	NN
cord-257662-viy65y72	99	39	prolonged	prolong	VBN
cord-257662-viy65y72	99	40	survival	survival	NN
cord-257662-viy65y72	99	41	of	of	IN
cord-257662-viy65y72	99	42	infected	infected	JJ
cord-257662-viy65y72	99	43	mice	mouse	NNS
cord-257662-viy65y72	99	44	,	,	,
cord-257662-viy65y72	99	45	while	while	IN
cord-257662-viy65y72	99	46	pharmacological	pharmacological	JJ
cord-257662-viy65y72	99	47	inactivation	inactivation	NN
cord-257662-viy65y72	99	48	throughout	throughout	IN
cord-257662-viy65y72	99	49	disease	disease	NN
cord-257662-viy65y72	99	50	did	do	VBD
cord-257662-viy65y72	99	51	not	not	RB
cord-257662-viy65y72	99	52	(	(	-LRB-
cord-257662-viy65y72	99	53	42	42	CD
cord-257662-viy65y72	99	54	)	)	-RRB-
cord-257662-viy65y72	99	55	.	.	.
cord-257662-viy65y72	100	1	Combined	combine	VBN
cord-257662-viy65y72	100	2	,	,	,
cord-257662-viy65y72	100	3	these	these	DT
cord-257662-viy65y72	100	4	data	datum	NNS
cord-257662-viy65y72	100	5	suggest	suggest	VBP
cord-257662-viy65y72	100	6	that	that	IN
cord-257662-viy65y72	100	7	although	although	IN
cord-257662-viy65y72	100	8	during	during	IN
cord-257662-viy65y72	100	9	DENV	DENV	NNP
cord-257662-viy65y72	100	10	infection	infection	NN
cord-257662-viy65y72	100	11	IFN	IFN	NNP
cord-257662-viy65y72	100	12	-	-	HYPH
cord-257662-viy65y72	100	13	γ	γ	NN
cord-257662-viy65y72	100	14	-	-	HYPH
cord-257662-viy65y72	100	15	induced	induce	VBN
cord-257662-viy65y72	100	16	NO	no	DT
cord-257662-viy65y72	100	17	production	production	NN
cord-257662-viy65y72	100	18	has	have	VBZ
cord-257662-viy65y72	100	19	a	a	DT
cord-257662-viy65y72	100	20	role	role	NN
cord-257662-viy65y72	100	21	in	in	IN
cord-257662-viy65y72	100	22	antiviral	antiviral	JJ
cord-257662-viy65y72	100	23	defense	defense	NN
cord-257662-viy65y72	100	24	,	,	,
cord-257662-viy65y72	100	25	it	-PRON-	PRP
cord-257662-viy65y72	100	26	is	be	VBZ
cord-257662-viy65y72	100	27	likely	likely	JJ
cord-257662-viy65y72	100	28	that	that	IN
cord-257662-viy65y72	100	29	dysregulation	dysregulation	NN
cord-257662-viy65y72	100	30	of	of	IN
cord-257662-viy65y72	100	31	the	the	DT
cord-257662-viy65y72	100	32	IL-12/18-IFN	IL-12/18-IFN	NNP
cord-257662-viy65y72	100	33	-	-	HYPH
cord-257662-viy65y72	100	34	γ	γ	NN
cord-257662-viy65y72	100	35	-	-	HYPH
cord-257662-viy65y72	100	36	NO	no	DT
cord-257662-viy65y72	100	37	axis	axis	NN
cord-257662-viy65y72	100	38	leads	lead	VBZ
cord-257662-viy65y72	100	39	to	to	IN
cord-257662-viy65y72	100	40	immune	immune	NN
cord-257662-viy65y72	100	41	-	-	HYPH
cord-257662-viy65y72	100	42	mediated	mediate	VBN
cord-257662-viy65y72	100	43	damage	damage	NN
cord-257662-viy65y72	100	44	in	in	IN
cord-257662-viy65y72	100	45	certain	certain	JJ
cord-257662-viy65y72	100	46	flavivirus	flavivirus	JJ
cord-257662-viy65y72	100	47	infections	infection	NNS
cord-257662-viy65y72	100	48	.	.	.
cord-257662-viy65y72	101	1	Along	along	IN
cord-257662-viy65y72	101	2	these	these	DT
cord-257662-viy65y72	101	3	lines	line	NNS
cord-257662-viy65y72	101	4	,	,	,
cord-257662-viy65y72	101	5	it	-PRON-	PRP
cord-257662-viy65y72	101	6	has	have	VBZ
cord-257662-viy65y72	101	7	also	also	RB
cord-257662-viy65y72	101	8	been	be	VBN
cord-257662-viy65y72	101	9	shown	show	VBN
cord-257662-viy65y72	101	10	that	that	DT
cord-257662-viy65y72	101	11	treatment	treatment	NN
cord-257662-viy65y72	101	12	of	of	IN
cord-257662-viy65y72	101	13	mice	mouse	NNS
cord-257662-viy65y72	101	14	with	with	IN
cord-257662-viy65y72	101	15	a	a	DT
cord-257662-viy65y72	101	16	NOS	NOS	NNP
cord-257662-viy65y72	101	17	inhibitor	inhibitor	NN
cord-257662-viy65y72	101	18	increased	increase	VBN
cord-257662-viy65y72	101	19	mortality	mortality	NN
cord-257662-viy65y72	101	20	rates	rate	NNS
cord-257662-viy65y72	101	21	following	follow	VBG
cord-257662-viy65y72	101	22	Sindbis	Sindbis	NNP
cord-257662-viy65y72	101	23	virus	virus	NN
cord-257662-viy65y72	101	24	(	(	-LRB-
cord-257662-viy65y72	101	25	SINV	SINV	NNP
cord-257662-viy65y72	101	26	)	)	-RRB-
cord-257662-viy65y72	101	27	infection	infection	NN
cord-257662-viy65y72	101	28	(	(	-LRB-
cord-257662-viy65y72	101	29	43	43	CD
cord-257662-viy65y72	101	30	)	)	-RRB-
cord-257662-viy65y72	101	31	,	,	,
cord-257662-viy65y72	101	32	suggesting	suggest	VBG
cord-257662-viy65y72	101	33	a	a	DT
cord-257662-viy65y72	101	34	protective	protective	JJ
cord-257662-viy65y72	101	35	role	role	NN
cord-257662-viy65y72	101	36	for	for	IN
cord-257662-viy65y72	101	37	NO	no	NN
cord-257662-viy65y72	101	38	during	during	IN
cord-257662-viy65y72	101	39	this	this	DT
cord-257662-viy65y72	101	40	particular	particular	JJ
cord-257662-viy65y72	101	41	CNS	CNS	NNP
cord-257662-viy65y72	101	42	infection	infection	NN
cord-257662-viy65y72	101	43	.	.	.
cord-257662-viy65y72	102	1	However	however	RB
cord-257662-viy65y72	102	2	,	,	,
cord-257662-viy65y72	102	3	SINV	SINV	NNP
cord-257662-viy65y72	102	4	replication	replication	NN
cord-257662-viy65y72	102	5	in	in	IN
cord-257662-viy65y72	102	6	the	the	DT
cord-257662-viy65y72	102	7	brain	brain	NN
cord-257662-viy65y72	102	8	was	be	VBD
cord-257662-viy65y72	102	9	unaffected	unaffected	JJ
cord-257662-viy65y72	102	10	.	.	.
cord-257662-viy65y72	103	1	Furthermore	furthermore	RB
cord-257662-viy65y72	103	2	,	,	,
cord-257662-viy65y72	103	3	treatment	treatment	NN
cord-257662-viy65y72	103	4	of	of	IN
cord-257662-viy65y72	103	5	neuroblastoma	neuroblastoma	NN
cord-257662-viy65y72	103	6	cells	cell	NNS
cord-257662-viy65y72	103	7	with	with	IN
cord-257662-viy65y72	103	8	NO	no	DT
cord-257662-viy65y72	103	9	donors	donor	NNS
cord-257662-viy65y72	103	10	had	have	VBD
cord-257662-viy65y72	103	11	little	little	JJ
cord-257662-viy65y72	103	12	effect	effect	NN
cord-257662-viy65y72	103	13	on	on	IN
cord-257662-viy65y72	103	14	SINV	SINV	NNP
cord-257662-viy65y72	103	15	replication	replication	NN
cord-257662-viy65y72	103	16	but	but	CC
cord-257662-viy65y72	103	17	increased	increase	VBN
cord-257662-viy65y72	103	18	cell	cell	NN
cord-257662-viy65y72	103	19	viability	viability	NN
cord-257662-viy65y72	103	20	(	(	-LRB-
cord-257662-viy65y72	103	21	43	43	CD
cord-257662-viy65y72	103	22	)	)	-RRB-
cord-257662-viy65y72	103	23	.	.	.
cord-257662-viy65y72	104	1	These	these	DT
cord-257662-viy65y72	104	2	data	datum	NNS
cord-257662-viy65y72	104	3	suggest	suggest	VBP
cord-257662-viy65y72	104	4	that	that	IN
cord-257662-viy65y72	104	5	NO	no	NN
cord-257662-viy65y72	104	6	protects	protect	VBZ
cord-257662-viy65y72	104	7	mice	mouse	NNS
cord-257662-viy65y72	104	8	from	from	IN
cord-257662-viy65y72	104	9	fatal	fatal	JJ
cord-257662-viy65y72	104	10	SINV	SINV	NNP
cord-257662-viy65y72	104	11	-	-	HYPH
cord-257662-viy65y72	104	12	induced	induce	VBN
cord-257662-viy65y72	104	13	encephalitis	encephalitis	RB
cord-257662-viy65y72	104	14	by	by	IN
cord-257662-viy65y72	104	15	a	a	DT
cord-257662-viy65y72	104	16	distinct	distinct	JJ
cord-257662-viy65y72	104	17	mechanism	mechanism	NN
cord-257662-viy65y72	104	18	that	that	WDT
cord-257662-viy65y72	104	19	does	do	VBZ
cord-257662-viy65y72	104	20	not	not	RB
cord-257662-viy65y72	104	21	directly	directly	RB
cord-257662-viy65y72	104	22	involve	involve	VB
cord-257662-viy65y72	104	23	the	the	DT
cord-257662-viy65y72	104	24	inhibition	inhibition	NN
cord-257662-viy65y72	104	25	of	of	IN
cord-257662-viy65y72	104	26	virus	virus	NN
cord-257662-viy65y72	104	27	growth	growth	NN
cord-257662-viy65y72	104	28	but	but	CC
cord-257662-viy65y72	104	29	rather	rather	RB
cord-257662-viy65y72	104	30	may	may	MD
cord-257662-viy65y72	104	31	enhance	enhance	VB
cord-257662-viy65y72	104	32	survival	survival	NN
cord-257662-viy65y72	104	33	of	of	IN
cord-257662-viy65y72	104	34	the	the	DT
cord-257662-viy65y72	104	35	infected	infected	JJ
cord-257662-viy65y72	104	36	neuron	neuron	NN
cord-257662-viy65y72	104	37	until	until	IN
cord-257662-viy65y72	104	38	the	the	DT
cord-257662-viy65y72	104	39	immune	immune	JJ
cord-257662-viy65y72	104	40	response	response	NN
cord-257662-viy65y72	104	41	can	can	MD
cord-257662-viy65y72	104	42	control	control	VB
cord-257662-viy65y72	104	43	virus	virus	NN
cord-257662-viy65y72	104	44	replication	replication	NN
cord-257662-viy65y72	104	45	.	.	.
cord-257662-viy65y72	105	1	Nitric	nitric	NN
cord-257662-viy65y72	105	2	oxide	oxide	NN
cord-257662-viy65y72	105	3	also	also	RB
cord-257662-viy65y72	105	4	plays	play	VBZ
cord-257662-viy65y72	105	5	an	an	DT
cord-257662-viy65y72	105	6	antiviral	antiviral	JJ
cord-257662-viy65y72	105	7	role	role	NN
cord-257662-viy65y72	105	8	during	during	IN
cord-257662-viy65y72	105	9	CNS	CNS	NNP
cord-257662-viy65y72	105	10	infection	infection	NN
cord-257662-viy65y72	105	11	with	with	IN
cord-257662-viy65y72	105	12	reovirus	reovirus	NNP
cord-257662-viy65y72	105	13	.	.	.
cord-257662-viy65y72	106	1	Infection	infection	NN
cord-257662-viy65y72	106	2	of	of	IN
cord-257662-viy65y72	106	3	neonatal	neonatal	JJ
cord-257662-viy65y72	106	4	mice	mouse	NNS
cord-257662-viy65y72	106	5	with	with	IN
cord-257662-viy65y72	106	6	the	the	DT
cord-257662-viy65y72	106	7	prototypic	prototypic	NNP
cord-257662-viy65y72	106	8	neurotropic	neurotropic	NNP
cord-257662-viy65y72	106	9	reovirus	reovirus	NNP
cord-257662-viy65y72	106	10	strain	strain	NNP
cord-257662-viy65y72	106	11	(	(	-LRB-
cord-257662-viy65y72	106	12	T3A	t3a	NN
cord-257662-viy65y72	106	13	)	)	-RRB-
cord-257662-viy65y72	106	14	induced	induce	VBN
cord-257662-viy65y72	106	15	iNOS	inos	JJ
cord-257662-viy65y72	106	16	expression	expression	NN
cord-257662-viy65y72	106	17	in	in	IN
cord-257662-viy65y72	106	18	brain	brain	NN
cord-257662-viy65y72	106	19	areas	area	NNS
cord-257662-viy65y72	106	20	demonstrating	demonstrate	VBG
cord-257662-viy65y72	106	21	reovirus	reovirus	NNP
cord-257662-viy65y72	106	22	antigen	antigen	NN
cord-257662-viy65y72	106	23	expression	expression	NN
cord-257662-viy65y72	106	24	and	and	CC
cord-257662-viy65y72	106	25	associated	associated	JJ
cord-257662-viy65y72	106	26	virus	virus	NN
cord-257662-viy65y72	106	27	-	-	HYPH
cord-257662-viy65y72	106	28	induced	induce	VBN
cord-257662-viy65y72	106	29	injury	injury	NN
cord-257662-viy65y72	106	30	(	(	-LRB-
cord-257662-viy65y72	106	31	44	44	CD
cord-257662-viy65y72	106	32	)	)	-RRB-
cord-257662-viy65y72	106	33	.	.	.
cord-257662-viy65y72	107	1	Reovirus	Reovirus	NNP
cord-257662-viy65y72	107	2	also	also	RB
cord-257662-viy65y72	107	3	induced	induce	VBD
cord-257662-viy65y72	107	4	iNOS	inos	JJ
cord-257662-viy65y72	107	5	expression	expression	NN
cord-257662-viy65y72	107	6	following	follow	VBG
cord-257662-viy65y72	107	7	in	in	IN
cord-257662-viy65y72	107	8	vitro	vitro	FW
cord-257662-viy65y72	107	9	infection	infection	NN
cord-257662-viy65y72	107	10	of	of	IN
cord-257662-viy65y72	107	11	primary	primary	JJ
cord-257662-viy65y72	107	12	neuronal	neuronal	JJ
cord-257662-viy65y72	107	13	and	and	CC
cord-257662-viy65y72	107	14	glial	glial	JJ
cord-257662-viy65y72	107	15	cultures	culture	NNS
cord-257662-viy65y72	107	16	.	.	.
cord-257662-viy65y72	108	1	Reovirus	Reovirus	NNP
cord-257662-viy65y72	108	2	was	be	VBD
cord-257662-viy65y72	108	3	shown	show	VBN
cord-257662-viy65y72	108	4	to	to	TO
cord-257662-viy65y72	108	5	infect	infect	VB
cord-257662-viy65y72	108	6	a	a	DT
cord-257662-viy65y72	108	7	subpopulation	subpopulation	NN
cord-257662-viy65y72	108	8	of	of	IN
cord-257662-viy65y72	108	9	microglial	microglial	JJ
cord-257662-viy65y72	108	10	cells	cell	NNS
cord-257662-viy65y72	108	11	in	in	IN
cord-257662-viy65y72	108	12	vitro	vitro	FW
cord-257662-viy65y72	108	13	(	(	-LRB-
cord-257662-viy65y72	108	14	44	44	CD
cord-257662-viy65y72	108	15	)	)	-RRB-
cord-257662-viy65y72	108	16	,	,	,
cord-257662-viy65y72	108	17	suggesting	suggest	VBG
cord-257662-viy65y72	108	18	that	that	IN
cord-257662-viy65y72	108	19	direct	direct	JJ
cord-257662-viy65y72	108	20	virus	virus	NN
cord-257662-viy65y72	108	21	interaction	interaction	NN
cord-257662-viy65y72	108	22	may	may	MD
cord-257662-viy65y72	108	23	induce	induce	VB
cord-257662-viy65y72	108	24	iNOS	inos	RP
cord-257662-viy65y72	108	25	in	in	IN
cord-257662-viy65y72	108	26	this	this	DT
cord-257662-viy65y72	108	27	specialized	specialized	JJ
cord-257662-viy65y72	108	28	population	population	NN
cord-257662-viy65y72	108	29	of	of	IN
cord-257662-viy65y72	108	30	macrophages	macrophage	NNS
cord-257662-viy65y72	108	31	.	.	.
cord-257662-viy65y72	109	1	Treatment	treatment	NN
cord-257662-viy65y72	109	2	of	of	IN
cord-257662-viy65y72	109	3	neuronal	neuronal	JJ
cord-257662-viy65y72	109	4	cultures	culture	NNS
cord-257662-viy65y72	109	5	with	with	IN
cord-257662-viy65y72	109	6	an	an	DT
cord-257662-viy65y72	109	7	NO	no	DT
cord-257662-viy65y72	109	8	donor	donor	NN
cord-257662-viy65y72	109	9	inhibited	inhibit	VBN
cord-257662-viy65y72	109	10	viral	viral	JJ
cord-257662-viy65y72	109	11	replication	replication	NN
cord-257662-viy65y72	109	12	whereas	whereas	IN
cord-257662-viy65y72	109	13	a	a	DT
cord-257662-viy65y72	109	14	NOS	NOS	NNP
cord-257662-viy65y72	109	15	inhibitor	inhibitor	NN
cord-257662-viy65y72	109	16	increased	increase	VBN
cord-257662-viy65y72	109	17	viral	viral	JJ
cord-257662-viy65y72	109	18	growth	growth	NN
cord-257662-viy65y72	109	19	(	(	-LRB-
cord-257662-viy65y72	109	20	44	44	CD
cord-257662-viy65y72	109	21	)	)	-RRB-
cord-257662-viy65y72	109	22	,	,	,
cord-257662-viy65y72	109	23	suggesting	suggest	VBG
cord-257662-viy65y72	109	24	iNOS	inos	JJ
cord-257662-viy65y72	109	25	has	have	VBZ
cord-257662-viy65y72	109	26	the	the	DT
cord-257662-viy65y72	109	27	potential	potential	NN
cord-257662-viy65y72	109	28	to	to	TO
cord-257662-viy65y72	109	29	exert	exert	VB
cord-257662-viy65y72	109	30	antiviral	antiviral	JJ
cord-257662-viy65y72	109	31	activity	activity	NN
cord-257662-viy65y72	109	32	in	in	IN
cord-257662-viy65y72	109	33	vivo	vivo	NNP
cord-257662-viy65y72	109	34	.	.	.
cord-257662-viy65y72	110	1	Finally	finally	RB
cord-257662-viy65y72	110	2	,	,	,
cord-257662-viy65y72	110	3	coxsackievirus	coxsackievirus	NNP
cord-257662-viy65y72	110	4	infection	infection	NN
cord-257662-viy65y72	110	5	has	have	VBZ
cord-257662-viy65y72	110	6	been	be	VBN
cord-257662-viy65y72	110	7	shown	show	VBN
cord-257662-viy65y72	110	8	to	to	TO
cord-257662-viy65y72	110	9	induce	induce	VB
cord-257662-viy65y72	110	10	expression	expression	NN
cord-257662-viy65y72	110	11	of	of	IN
cord-257662-viy65y72	110	12	iNOS	inos	NN
cord-257662-viy65y72	110	13	in	in	IN
cord-257662-viy65y72	110	14	macrophages	macrophage	NNS
cord-257662-viy65y72	110	15	infiltrating	infiltrate	VBG
cord-257662-viy65y72	110	16	the	the	DT
cord-257662-viy65y72	110	17	hearts	heart	NNS
cord-257662-viy65y72	110	18	of	of	IN
cord-257662-viy65y72	110	19	infected	infected	JJ
cord-257662-viy65y72	110	20	mice	mouse	NNS
cord-257662-viy65y72	110	21	(	(	-LRB-
cord-257662-viy65y72	110	22	17	17	CD
cord-257662-viy65y72	110	23	)	)	-RRB-
cord-257662-viy65y72	110	24	.	.	.
cord-257662-viy65y72	111	1	Treatment	treatment	NN
cord-257662-viy65y72	111	2	of	of	IN
cord-257662-viy65y72	111	3	WT	WT	NNP
cord-257662-viy65y72	111	4	mice	mouse	NNS
cord-257662-viy65y72	111	5	with	with	IN
cord-257662-viy65y72	111	6	a	a	DT
cord-257662-viy65y72	111	7	NOS	NOS	NNP
cord-257662-viy65y72	111	8	inhibitor	inhibitor	NN
cord-257662-viy65y72	111	9	and	and	CC
cord-257662-viy65y72	111	10	infection	infection	NN
cord-257662-viy65y72	111	11	of	of	IN
cord-257662-viy65y72	111	12	Nos2	Nos2	NNP
cord-257662-viy65y72	111	13	−/−	−/−	NNP
cord-257662-viy65y72	111	14	mice	mouse	NNS
cord-257662-viy65y72	111	15	resulted	result	VBD
cord-257662-viy65y72	111	16	in	in	IN
cord-257662-viy65y72	111	17	more	more	RBR
cord-257662-viy65y72	111	18	severe	severe	JJ
cord-257662-viy65y72	111	19	coxsackievirus	coxsackievirus	NN
cord-257662-viy65y72	111	20	-	-	HYPH
cord-257662-viy65y72	111	21	induced	induce	VBN
cord-257662-viy65y72	111	22	pancreatitis	pancreatitis	NN
cord-257662-viy65y72	111	23	and	and	CC
cord-257662-viy65y72	111	24	myocarditis	myocarditis	NN
cord-257662-viy65y72	111	25	,	,	,
cord-257662-viy65y72	111	26	elevated	elevate	VBN
cord-257662-viy65y72	111	27	viral	viral	JJ
cord-257662-viy65y72	111	28	loads	load	NNS
cord-257662-viy65y72	111	29	in	in	IN
cord-257662-viy65y72	111	30	tissues	tissue	NNS
cord-257662-viy65y72	111	31	,	,	,
cord-257662-viy65y72	111	32	and	and	CC
cord-257662-viy65y72	111	33	decreased	decrease	VBD
cord-257662-viy65y72	111	34	survival	survival	NN
cord-257662-viy65y72	111	35	compared	compare	VBN
cord-257662-viy65y72	111	36	to	to	IN
cord-257662-viy65y72	111	37	WT	wt	NN
cord-257662-viy65y72	111	38	mice	mouse	NNS
cord-257662-viy65y72	111	39	following	follow	VBG
cord-257662-viy65y72	111	40	coxsackievirus	coxsackievirus	NNP
cord-257662-viy65y72	111	41	B3	B3	NNP
cord-257662-viy65y72	111	42	(	(	-LRB-
cord-257662-viy65y72	111	43	CVB3	CVB3	NNP
cord-257662-viy65y72	111	44	)	)	-RRB-
cord-257662-viy65y72	111	45	infection	infection	NN
cord-257662-viy65y72	111	46	(	(	-LRB-
cord-257662-viy65y72	111	47	14	14	CD
cord-257662-viy65y72	111	48	,	,	,
cord-257662-viy65y72	111	49	15	15	CD
cord-257662-viy65y72	111	50	,	,	,
cord-257662-viy65y72	111	51	17	17	CD
cord-257662-viy65y72	111	52	)	)	-RRB-
cord-257662-viy65y72	111	53	.	.	.
cord-257662-viy65y72	112	1	Similarly	similarly	RB
cord-257662-viy65y72	112	2	,	,	,
cord-257662-viy65y72	112	3	Nos2	Nos2	NNP
cord-257662-viy65y72	112	4	−/−	−/−	NNP
cord-257662-viy65y72	112	5	mice	mouse	NNS
cord-257662-viy65y72	112	6	infected	infect	VBN
cord-257662-viy65y72	112	7	with	with	IN
cord-257662-viy65y72	112	8	coxsackievirus	coxsackievirus	NNP
cord-257662-viy65y72	112	9	B4	B4	NNP
cord-257662-viy65y72	112	10	exhibited	exhibit	VBD
cord-257662-viy65y72	112	11	decreased	decreased	JJ
cord-257662-viy65y72	112	12	survival	survival	NN
cord-257662-viy65y72	112	13	and	and	CC
cord-257662-viy65y72	112	14	delayed	delay	VBN
cord-257662-viy65y72	112	15	viral	viral	JJ
cord-257662-viy65y72	112	16	clearance	clearance	NN
cord-257662-viy65y72	112	17	compared	compare	VBN
cord-257662-viy65y72	112	18	to	to	IN
cord-257662-viy65y72	112	19	WT	WT	NNP
cord-257662-viy65y72	112	20	mice	mouse	NNS
cord-257662-viy65y72	112	21	(	(	-LRB-
cord-257662-viy65y72	112	22	16	16	CD
cord-257662-viy65y72	112	23	)	)	-RRB-
cord-257662-viy65y72	112	24	.	.	.
cord-257662-viy65y72	113	1	These	these	DT
cord-257662-viy65y72	113	2	data	datum	NNS
cord-257662-viy65y72	113	3	suggest	suggest	VBP
cord-257662-viy65y72	113	4	an	an	DT
cord-257662-viy65y72	113	5	antiviral	antiviral	JJ
cord-257662-viy65y72	113	6	effect	effect	NN
cord-257662-viy65y72	113	7	of	of	IN
cord-257662-viy65y72	113	8	NO	no	NN
cord-257662-viy65y72	113	9	against	against	IN
cord-257662-viy65y72	113	10	coxsackievirus	coxsackievirus	NN
cord-257662-viy65y72	113	11	infection	infection	NN
cord-257662-viy65y72	113	12	.	.	.
cord-257662-viy65y72	114	1	Consistent	consistent	JJ
cord-257662-viy65y72	114	2	with	with	IN
cord-257662-viy65y72	114	3	this	this	DT
cord-257662-viy65y72	114	4	,	,	,
cord-257662-viy65y72	114	5	it	-PRON-	PRP
cord-257662-viy65y72	114	6	was	be	VBD
cord-257662-viy65y72	114	7	demonstrated	demonstrate	VBN
cord-257662-viy65y72	114	8	that	that	IN
cord-257662-viy65y72	114	9	NO	no	DT
cord-257662-viy65y72	114	10	inhibits	inhibit	VBZ
cord-257662-viy65y72	114	11	the	the	DT
cord-257662-viy65y72	114	12	2A	2a	CD
cord-257662-viy65y72	114	13	and	and	CC
cord-257662-viy65y72	114	14	3C	3C	NNP
cord-257662-viy65y72	114	15	proteinases	proteinases	NNP
cord-257662-viy65y72	114	16	of	of	IN
cord-257662-viy65y72	114	17	CVB3	CVB3	NNPS
cord-257662-viy65y72	115	1	in	in	IN
cord-257662-viy65y72	115	2	vitro	vitro	FW
cord-257662-viy65y72	115	3	(	(	-LRB-
cord-257662-viy65y72	115	4	91	91	CD
cord-257662-viy65y72	115	5	)	)	-RRB-
cord-257662-viy65y72	115	6	.	.	.
cord-257662-viy65y72	116	1	Additionally	additionally	RB
cord-257662-viy65y72	116	2	,	,	,
cord-257662-viy65y72	116	3	CVB3-infected	cvb3-infecte	VBN
cord-257662-viy65y72	116	4	outbred	outbred	JJ
cord-257662-viy65y72	116	5	mice	mouse	NNS
cord-257662-viy65y72	116	6	showed	show	VBD
cord-257662-viy65y72	116	7	significantly	significantly	RB
cord-257662-viy65y72	116	8	reduced	reduce	VBN
cord-257662-viy65y72	116	9	signs	sign	NNS
cord-257662-viy65y72	116	10	of	of	IN
cord-257662-viy65y72	116	11	myocarditis	myocarditis	NN
cord-257662-viy65y72	116	12	after	after	IN
cord-257662-viy65y72	116	13	treatment	treatment	NN
cord-257662-viy65y72	116	14	with	with	IN
cord-257662-viy65y72	116	15	NO	no	DT
cord-257662-viy65y72	116	16	donors	donor	NNS
cord-257662-viy65y72	116	17	(	(	-LRB-
cord-257662-viy65y72	116	18	91	91	CD
cord-257662-viy65y72	116	19	)	)	-RRB-
cord-257662-viy65y72	116	20	.	.	.
cord-257662-viy65y72	117	1	Despite	despite	IN
cord-257662-viy65y72	117	2	its	-PRON-	PRP$
cord-257662-viy65y72	117	3	protective	protective	JJ
cord-257662-viy65y72	117	4	capacity	capacity	NN
cord-257662-viy65y72	117	5	during	during	IN
cord-257662-viy65y72	117	6	some	some	DT
cord-257662-viy65y72	117	7	viral	viral	JJ
cord-257662-viy65y72	117	8	infections	infection	NNS
cord-257662-viy65y72	117	9	,	,	,
cord-257662-viy65y72	117	10	NO	no	UH
cord-257662-viy65y72	117	11	can	can	MD
cord-257662-viy65y72	117	12	also	also	RB
cord-257662-viy65y72	117	13	contribute	contribute	VB
cord-257662-viy65y72	117	14	to	to	IN
cord-257662-viy65y72	117	15	immunopathology	immunopathology	NN
cord-257662-viy65y72	117	16	.	.	.
cord-257662-viy65y72	118	1	The	the	DT
cord-257662-viy65y72	118	2	pathological	pathological	JJ
cord-257662-viy65y72	118	3	effects	effect	NNS
cord-257662-viy65y72	118	4	of	of	IN
cord-257662-viy65y72	118	5	NO	no	DT
cord-257662-viy65y72	118	6	are	be	VBP
cord-257662-viy65y72	118	7	likely	likely	JJ
cord-257662-viy65y72	118	8	due	due	JJ
cord-257662-viy65y72	118	9	,	,	,
cord-257662-viy65y72	118	10	at	at	IN
cord-257662-viy65y72	118	11	least	least	JJS
cord-257662-viy65y72	118	12	in	in	IN
cord-257662-viy65y72	118	13	part	part	NN
cord-257662-viy65y72	118	14	,	,	,
cord-257662-viy65y72	118	15	to	to	IN
cord-257662-viy65y72	118	16	oxidative	oxidative	JJ
cord-257662-viy65y72	118	17	damage	damage	NN
cord-257662-viy65y72	118	18	caused	cause	VBN
cord-257662-viy65y72	118	19	by	by	IN
cord-257662-viy65y72	118	20	the	the	DT
cord-257662-viy65y72	118	21	interaction	interaction	NN
cord-257662-viy65y72	118	22	of	of	IN
cord-257662-viy65y72	118	23	NO	no	DT
cord-257662-viy65y72	118	24	with	with	IN
cord-257662-viy65y72	118	25	oxygen	oxygen	NN
cord-257662-viy65y72	118	26	radicals	radical	NNS
cord-257662-viy65y72	118	27	such	such	JJ
cord-257662-viy65y72	118	28	as	as	IN
cord-257662-viy65y72	118	29	the	the	DT
cord-257662-viy65y72	118	30	superoxide	superoxide	NN
cord-257662-viy65y72	118	31	anion	anion	NN
cord-257662-viy65y72	118	32	radical	radical	JJ
cord-257662-viy65y72	118	33	O	o	NN
cord-257662-viy65y72	118	34	−	−	NN
cord-257662-viy65y72	118	35	2	2	CD
cord-257662-viy65y72	118	36	and	and	CC
cord-257662-viy65y72	118	37	hydrogen	hydrogen	NN
cord-257662-viy65y72	118	38	peroxide	peroxide	NN
cord-257662-viy65y72	118	39	(	(	-LRB-
cord-257662-viy65y72	118	40	H	h	NN
cord-257662-viy65y72	118	41	2	2	CD
cord-257662-viy65y72	118	42	O	o	NN
cord-257662-viy65y72	118	43	2	2	CD
cord-257662-viy65y72	118	44	)	)	-RRB-
cord-257662-viy65y72	118	45	.	.	.
cord-257662-viy65y72	119	1	For	for	IN
cord-257662-viy65y72	119	2	example	example	NN
cord-257662-viy65y72	119	3	,	,	,
cord-257662-viy65y72	119	4	although	although	IN
cord-257662-viy65y72	119	5	addition	addition	NN
cord-257662-viy65y72	119	6	of	of	IN
cord-257662-viy65y72	119	7	an	an	DT
cord-257662-viy65y72	119	8	NO	no	JJ
cord-257662-viy65y72	119	9	donor	donor	NN
cord-257662-viy65y72	119	10	to	to	IN
cord-257662-viy65y72	119	11	virusinfected	virusinfecte	VBN
cord-257662-viy65y72	119	12	MDCK	MDCK	NNP
cord-257662-viy65y72	119	13	cells	cell	NNS
cord-257662-viy65y72	119	14	reduced	reduce	VBN
cord-257662-viy65y72	119	15	influenza	influenza	NN
cord-257662-viy65y72	119	16	A	a	NN
cord-257662-viy65y72	119	17	and	and	CC
cord-257662-viy65y72	119	18	B	b	NN
cord-257662-viy65y72	119	19	viral	viral	JJ
cord-257662-viy65y72	119	20	burden	burden	NN
cord-257662-viy65y72	119	21	in	in	IN
cord-257662-viy65y72	119	22	vitro	vitro	FW
cord-257662-viy65y72	119	23	(	(	-LRB-
cord-257662-viy65y72	119	24	45	45	CD
cord-257662-viy65y72	119	25	)	)	-RRB-
cord-257662-viy65y72	119	26	,	,	,
cord-257662-viy65y72	119	27	treatment	treatment	NN
cord-257662-viy65y72	119	28	of	of	IN
cord-257662-viy65y72	119	29	mice	mouse	NNS
cord-257662-viy65y72	119	30	with	with	IN
cord-257662-viy65y72	119	31	inhaled	inhale	VBN
cord-257662-viy65y72	119	32	NO	NO	NNP
cord-257662-viy65y72	119	33	(	(	-LRB-
cord-257662-viy65y72	119	34	iNO	iNO	NNS
cord-257662-viy65y72	119	35	)	)	-RRB-
cord-257662-viy65y72	119	36	did	do	VBD
cord-257662-viy65y72	119	37	not	not	RB
cord-257662-viy65y72	119	38	decrease	decrease	VB
cord-257662-viy65y72	119	39	the	the	DT
cord-257662-viy65y72	119	40	viral	viral	JJ
cord-257662-viy65y72	119	41	load	load	NN
cord-257662-viy65y72	119	42	of	of	IN
cord-257662-viy65y72	119	43	influenza	influenza	NN
cord-257662-viy65y72	119	44	A	a	NN
cord-257662-viy65y72	119	45	(	(	-LRB-
cord-257662-viy65y72	119	46	mouse	mouse	NN
cord-257662-viy65y72	119	47	-	-	HYPH
cord-257662-viy65y72	119	48	adapted	adapt	VBN
cord-257662-viy65y72	119	49	H1N1	H1N1	NNP
cord-257662-viy65y72	119	50	strain)-infected	strain)-infected	NNP
cord-257662-viy65y72	119	51	mice	mouse	NNS
cord-257662-viy65y72	119	52	;	;	:
cord-257662-viy65y72	119	53	in	in	IN
cord-257662-viy65y72	119	54	fact	fact	NN
cord-257662-viy65y72	119	55	,	,	,
cord-257662-viy65y72	119	56	prophylactic	prophylactic	JJ
cord-257662-viy65y72	119	57	treatment	treatment	NN
cord-257662-viy65y72	119	58	with	with	IN
cord-257662-viy65y72	119	59	iNO	iNO	NNS
cord-257662-viy65y72	119	60	resulted	result	VBD
cord-257662-viy65y72	119	61	in	in	IN
cord-257662-viy65y72	119	62	enhanced	enhanced	JJ
cord-257662-viy65y72	119	63	weight	weight	NN
cord-257662-viy65y72	119	64	loss	loss	NN
cord-257662-viy65y72	119	65	and	and	CC
cord-257662-viy65y72	119	66	decreased	decrease	VBD
cord-257662-viy65y72	119	67	survival	survival	NN
cord-257662-viy65y72	119	68	following	follow	VBG
cord-257662-viy65y72	119	69	infection	infection	NN
cord-257662-viy65y72	119	70	(	(	-LRB-
cord-257662-viy65y72	119	71	46	46	CD
cord-257662-viy65y72	119	72	)	)	-RRB-
cord-257662-viy65y72	119	73	,	,	,
cord-257662-viy65y72	119	74	suggesting	suggest	VBG
cord-257662-viy65y72	119	75	a	a	DT
cord-257662-viy65y72	119	76	pathogenic	pathogenic	JJ
cord-257662-viy65y72	119	77	role	role	NN
cord-257662-viy65y72	119	78	for	for	IN
cord-257662-viy65y72	119	79	NO	no	NN
cord-257662-viy65y72	119	80	.	.	.
cord-257662-viy65y72	120	1	Consistent	consistent	JJ
cord-257662-viy65y72	120	2	with	with	IN
cord-257662-viy65y72	120	3	this	this	DT
cord-257662-viy65y72	120	4	,	,	,
cord-257662-viy65y72	120	5	chickens	chicken	NNS
cord-257662-viy65y72	120	6	,	,	,
cord-257662-viy65y72	120	7	which	which	WDT
cord-257662-viy65y72	120	8	show	show	VBP
cord-257662-viy65y72	120	9	a	a	DT
cord-257662-viy65y72	120	10	high	high	JJ
cord-257662-viy65y72	120	11	level	level	NN
cord-257662-viy65y72	120	12	of	of	IN
cord-257662-viy65y72	120	13	mortality	mortality	NN
cord-257662-viy65y72	120	14	and	and	CC
cord-257662-viy65y72	120	15	associated	associated	JJ
cord-257662-viy65y72	120	16	pathology	pathology	NN
cord-257662-viy65y72	120	17	following	follow	VBG
cord-257662-viy65y72	120	18	avian	avian	JJ
cord-257662-viy65y72	120	19	influenza	influenza	NN
cord-257662-viy65y72	120	20	infection	infection	NN
cord-257662-viy65y72	120	21	,	,	,
cord-257662-viy65y72	120	22	had	have	VBD
cord-257662-viy65y72	120	23	higher	high	JJR
cord-257662-viy65y72	120	24	levels	level	NNS
cord-257662-viy65y72	120	25	of	of	IN
cord-257662-viy65y72	120	26	iNOS	inos	JJ
cord-257662-viy65y72	120	27	expression	expression	NN
cord-257662-viy65y72	120	28	in	in	IN
cord-257662-viy65y72	120	29	the	the	DT
cord-257662-viy65y72	120	30	lungs	lung	NNS
cord-257662-viy65y72	120	31	compared	compare	VBN
cord-257662-viy65y72	120	32	with	with	IN
cord-257662-viy65y72	120	33	H5N1	H5N1	NNP
cord-257662-viy65y72	120	34	influenza	influenza	NN
cord-257662-viy65y72	120	35	-	-	HYPH
cord-257662-viy65y72	120	36	infected	infect	VBN
cord-257662-viy65y72	120	37	ducks	duck	NNS
cord-257662-viy65y72	120	38	,	,	,
cord-257662-viy65y72	120	39	which	which	WDT
cord-257662-viy65y72	120	40	show	show	VBP
cord-257662-viy65y72	120	41	relatively	relatively	RB
cord-257662-viy65y72	120	42	minor	minor	JJ
cord-257662-viy65y72	120	43	symptoms	symptom	NNS
cord-257662-viy65y72	120	44	following	follow	VBG
cord-257662-viy65y72	120	45	influenza	influenza	NN
cord-257662-viy65y72	120	46	infection	infection	NN
cord-257662-viy65y72	120	47	(	(	-LRB-
cord-257662-viy65y72	120	48	47	47	CD
cord-257662-viy65y72	120	49	)	)	-RRB-
cord-257662-viy65y72	120	50	.	.	.
cord-257662-viy65y72	121	1	Additionally	additionally	RB
cord-257662-viy65y72	121	2	,	,	,
cord-257662-viy65y72	121	3	Akaike	Akaike	NNP
cord-257662-viy65y72	121	4	and	and	CC
cord-257662-viy65y72	121	5	colleagues	colleague	NNS
cord-257662-viy65y72	121	6	(	(	-LRB-
cord-257662-viy65y72	121	7	48	48	CD
cord-257662-viy65y72	121	8	)	)	-RRB-
cord-257662-viy65y72	121	9	found	find	VBD
cord-257662-viy65y72	121	10	evidence	evidence	NN
cord-257662-viy65y72	121	11	of	of	IN
cord-257662-viy65y72	121	12	the	the	DT
cord-257662-viy65y72	121	13	production	production	NN
cord-257662-viy65y72	121	14	of	of	IN
cord-257662-viy65y72	121	15	peroxynitrite	peroxynitrite	NN
cord-257662-viy65y72	121	16	,	,	,
cord-257662-viy65y72	121	17	which	which	WDT
cord-257662-viy65y72	121	18	is	be	VBZ
cord-257662-viy65y72	121	19	generated	generate	VBN
cord-257662-viy65y72	121	20	through	through	IN
cord-257662-viy65y72	121	21	the	the	DT
cord-257662-viy65y72	121	22	reaction	reaction	NN
cord-257662-viy65y72	121	23	of	of	IN
cord-257662-viy65y72	121	24	NO	no	NN
cord-257662-viy65y72	121	25	and	and	CC
cord-257662-viy65y72	121	26	O	o	UH
cord-257662-viy65y72	121	27	2	2	CD
cord-257662-viy65y72	121	28	-	-	:
cord-257662-viy65y72	121	29	,	,	,
cord-257662-viy65y72	121	30	in	in	IN
cord-257662-viy65y72	121	31	the	the	DT
cord-257662-viy65y72	121	32	lungs	lung	NNS
cord-257662-viy65y72	121	33	of	of	IN
cord-257662-viy65y72	121	34	influenza	influenza	NN
cord-257662-viy65y72	121	35	A	a	NN
cord-257662-viy65y72	122	1	(	(	-LRB-
cord-257662-viy65y72	122	2	mouse	mouse	NN
cord-257662-viy65y72	122	3	-	-	HYPH
cord-257662-viy65y72	122	4	adapted	adapt	VBN
cord-257662-viy65y72	122	5	H2N2	H2N2	NNP
cord-257662-viy65y72	122	6	strain)-infected	strain)-infected	NNP
cord-257662-viy65y72	122	7	mice	mouse	NNS
cord-257662-viy65y72	122	8	.	.	.
cord-257662-viy65y72	123	1	Moreover	moreover	RB
cord-257662-viy65y72	123	2	,	,	,
cord-257662-viy65y72	123	3	inhibition	inhibition	NN
cord-257662-viy65y72	123	4	of	of	IN
cord-257662-viy65y72	123	5	NOS	NOS	NNP
cord-257662-viy65y72	123	6	resulted	result	VBD
cord-257662-viy65y72	123	7	in	in	IN
cord-257662-viy65y72	123	8	enhanced	enhance	VBN
cord-257662-viy65y72	123	9	survival	survival	NN
cord-257662-viy65y72	123	10	and	and	CC
cord-257662-viy65y72	123	11	decreased	decrease	VBD
cord-257662-viy65y72	123	12	pneumonia	pneumonia	NN
cord-257662-viy65y72	123	13	,	,	,
cord-257662-viy65y72	123	14	but	but	CC
cord-257662-viy65y72	123	15	not	not	RB
cord-257662-viy65y72	123	16	decreased	decrease	VBD
cord-257662-viy65y72	123	17	viral	viral	JJ
cord-257662-viy65y72	123	18	loads	load	NNS
cord-257662-viy65y72	123	19	,	,	,
cord-257662-viy65y72	123	20	in	in	IN
cord-257662-viy65y72	123	21	influenzainfected	influenzainfected	JJ
cord-257662-viy65y72	123	22	mice	mouse	NNS
cord-257662-viy65y72	123	23	(	(	-LRB-
cord-257662-viy65y72	123	24	48	48	CD
cord-257662-viy65y72	123	25	,	,	,
cord-257662-viy65y72	123	26	49	49	CD
cord-257662-viy65y72	123	27	)	)	-RRB-
cord-257662-viy65y72	123	28	,	,	,
cord-257662-viy65y72	123	29	suggesting	suggest	VBG
cord-257662-viy65y72	123	30	that	that	IN
cord-257662-viy65y72	123	31	NO	NO	NNP
cord-257662-viy65y72	123	32	was	be	VBD
cord-257662-viy65y72	123	33	contributing	contribute	VBG
cord-257662-viy65y72	123	34	to	to	IN
cord-257662-viy65y72	123	35	pathogenesis	pathogenesis	NN
cord-257662-viy65y72	123	36	rather	rather	RB
cord-257662-viy65y72	123	37	than	than	IN
cord-257662-viy65y72	123	38	having	have	VBG
cord-257662-viy65y72	123	39	direct	direct	JJ
cord-257662-viy65y72	123	40	antiviral	antiviral	JJ
cord-257662-viy65y72	123	41	effects	effect	NNS
cord-257662-viy65y72	123	42	.	.	.
cord-257662-viy65y72	124	1	Nos2	Nos2	NNP
cord-257662-viy65y72	124	2	−/−	−/−	NNP
cord-257662-viy65y72	124	3	mice	mouse	NNS
cord-257662-viy65y72	124	4	also	also	RB
cord-257662-viy65y72	124	5	survived	survive	VBD
cord-257662-viy65y72	124	6	a	a	DT
cord-257662-viy65y72	124	7	lethal	lethal	JJ
cord-257662-viy65y72	124	8	dose	dose	NN
cord-257662-viy65y72	124	9	of	of	IN
cord-257662-viy65y72	124	10	influenza	influenza	NN
cord-257662-viy65y72	124	11	A	a	DT
cord-257662-viy65y72	124	12	virus	virus	NN
cord-257662-viy65y72	124	13	(	(	-LRB-
cord-257662-viy65y72	124	14	PR/8/34	pr/8/34	CD
cord-257662-viy65y72	124	15	strain	strain	NN
cord-257662-viy65y72	124	16	)	)	-RRB-
cord-257662-viy65y72	124	17	infection	infection	NN
cord-257662-viy65y72	124	18	with	with	IN
cord-257662-viy65y72	124	19	little	little	JJ
cord-257662-viy65y72	124	20	histopathologic	histopathologic	JJ
cord-257662-viy65y72	124	21	evidence	evidence	NN
cord-257662-viy65y72	124	22	of	of	IN
cord-257662-viy65y72	124	23	pneumonitis	pneumonitis	NN
cord-257662-viy65y72	124	24	;	;	:
cord-257662-viy65y72	124	25	however	however	RB
cord-257662-viy65y72	124	26	,	,	,
cord-257662-viy65y72	124	27	in	in	IN
cord-257662-viy65y72	124	28	these	these	DT
cord-257662-viy65y72	124	29	studies	study	NNS
cord-257662-viy65y72	124	30	no	no	DT
cord-257662-viy65y72	124	31	infectious	infectious	JJ
cord-257662-viy65y72	124	32	virus	virus	NN
cord-257662-viy65y72	124	33	was	be	VBD
cord-257662-viy65y72	124	34	detected	detect	VBN
cord-257662-viy65y72	124	35	in	in	IN
cord-257662-viy65y72	124	36	Nos2	Nos2	NNP
cord-257662-viy65y72	124	37	−/−	−/−	NNP
cord-257662-viy65y72	124	38	mice	mouse	NNS
cord-257662-viy65y72	124	39	at	at	IN
cord-257662-viy65y72	124	40	day	day	NN
cord-257662-viy65y72	124	41	6	6	CD
cord-257662-viy65y72	124	42	after	after	IN
cord-257662-viy65y72	124	43	infection	infection	NN
cord-257662-viy65y72	124	44	(	(	-LRB-
cord-257662-viy65y72	124	45	49	49	CD
cord-257662-viy65y72	124	46	)	)	-RRB-
cord-257662-viy65y72	124	47	.	.	.
cord-257662-viy65y72	125	1	The	the	DT
cord-257662-viy65y72	125	2	enhanced	enhanced	JJ
cord-257662-viy65y72	125	3	viral	viral	JJ
cord-257662-viy65y72	125	4	control	control	NN
cord-257662-viy65y72	125	5	in	in	IN
cord-257662-viy65y72	125	6	Nos2	Nos2	NNP
cord-257662-viy65y72	125	7	−/−	−/−	NNP
cord-257662-viy65y72	125	8	mice	mouse	NNS
cord-257662-viy65y72	125	9	was	be	VBD
cord-257662-viy65y72	125	10	shown	show	VBN
cord-257662-viy65y72	125	11	to	to	TO
cord-257662-viy65y72	125	12	require	require	VB
cord-257662-viy65y72	125	13	the	the	DT
cord-257662-viy65y72	125	14	activity	activity	NN
cord-257662-viy65y72	125	15	of	of	IN
cord-257662-viy65y72	125	16	IFN	IFN	NNP
cord-257662-viy65y72	125	17	-	-	HYPH
cord-257662-viy65y72	125	18	γ	γ	NNP
cord-257662-viy65y72	125	19	(	(	-LRB-
cord-257662-viy65y72	125	20	51	51	CD
cord-257662-viy65y72	125	21	)	)	-RRB-
cord-257662-viy65y72	125	22	,	,	,
cord-257662-viy65y72	125	23	with	with	IN
cord-257662-viy65y72	125	24	Nos2	Nos2	NNP
cord-257662-viy65y72	125	25	−/−	−/−	NNP
cord-257662-viy65y72	125	26	mice	mouse	NNS
cord-257662-viy65y72	125	27	also	also	RB
cord-257662-viy65y72	125	28	producing	produce	VBG
cord-257662-viy65y72	125	29	increased	increase	VBN
cord-257662-viy65y72	125	30	virusspecific	virusspecific	NNP
cord-257662-viy65y72	125	31	IgG2a	igg2a	JJ
cord-257662-viy65y72	125	32	antibody	antibody	NN
cord-257662-viy65y72	125	33	titers	titer	NNS
cord-257662-viy65y72	125	34	(	(	-LRB-
cord-257662-viy65y72	125	35	50	50	CD
cord-257662-viy65y72	125	36	)	)	-RRB-
cord-257662-viy65y72	125	37	.	.	.
cord-257662-viy65y72	126	1	Additionally	additionally	RB
cord-257662-viy65y72	126	2	,	,	,
cord-257662-viy65y72	126	3	genetic	genetic	JJ
cord-257662-viy65y72	126	4	deletion	deletion	NN
cord-257662-viy65y72	126	5	Frontiers	Frontiers	NNPS
cord-257662-viy65y72	126	6	in	in	IN
cord-257662-viy65y72	126	7	Immunology	Immunology	NNP
cord-257662-viy65y72	126	8	|	|	NNP
cord-257662-viy65y72	126	9	Antigen	Antigen	NNP
cord-257662-viy65y72	126	10	Presenting	present	VBG
cord-257662-viy65y72	126	11	Cell	cell	NN
cord-257662-viy65y72	126	12	Biology	biology	NN
cord-257662-viy65y72	126	13	of	of	IN
cord-257662-viy65y72	126	14	Nos2	Nos2	NNP
cord-257662-viy65y72	126	15	or	or	CC
cord-257662-viy65y72	126	16	pharmacologic	pharmacologic	JJ
cord-257662-viy65y72	126	17	inhibition	inhibition	NN
cord-257662-viy65y72	126	18	of	of	IN
cord-257662-viy65y72	126	19	NOS	NOS	NNP
cord-257662-viy65y72	126	20	enhanced	enhance	VBN
cord-257662-viy65y72	126	21	survival	survival	NN
cord-257662-viy65y72	126	22	of	of	IN
cord-257662-viy65y72	126	23	mice	mouse	NNS
cord-257662-viy65y72	126	24	inoculated	inoculate	VBN
cord-257662-viy65y72	126	25	with	with	IN
cord-257662-viy65y72	126	26	the	the	DT
cord-257662-viy65y72	126	27	highly	highly	RB
cord-257662-viy65y72	126	28	pathogenic	pathogenic	JJ
cord-257662-viy65y72	126	29	(	(	-LRB-
cord-257662-viy65y72	126	30	non	non	JJ
cord-257662-viy65y72	126	31	-	-	JJ
cord-257662-viy65y72	126	32	mouse	mouse	NN
cord-257662-viy65y72	126	33	-	-	HYPH
cord-257662-viy65y72	126	34	adapted	adapt	VBN
cord-257662-viy65y72	126	35	)	)	-RRB-
cord-257662-viy65y72	126	36	1918	1918	CD
cord-257662-viy65y72	126	37	influenza	influenza	NN
cord-257662-viy65y72	126	38	virus	virus	NN
cord-257662-viy65y72	126	39	strain	strain	NN
cord-257662-viy65y72	126	40	,	,	,
cord-257662-viy65y72	126	41	although	although	IN
cord-257662-viy65y72	126	42	mice	mouse	NNS
cord-257662-viy65y72	126	43	exhibited	exhibit	VBD
cord-257662-viy65y72	126	44	similar	similar	JJ
cord-257662-viy65y72	126	45	viral	viral	JJ
cord-257662-viy65y72	126	46	loads	load	NNS
cord-257662-viy65y72	126	47	to	to	TO
cord-257662-viy65y72	126	48	control	control	VB
cord-257662-viy65y72	126	49	mice	mouse	NNS
cord-257662-viy65y72	126	50	in	in	IN
cord-257662-viy65y72	126	51	lung	lung	NN
cord-257662-viy65y72	126	52	tissue	tissue	NN
cord-257662-viy65y72	126	53	at	at	IN
cord-257662-viy65y72	126	54	the	the	DT
cord-257662-viy65y72	126	55	peak	peak	NN
cord-257662-viy65y72	126	56	of	of	IN
cord-257662-viy65y72	126	57	viral	viral	JJ
cord-257662-viy65y72	126	58	replication	replication	NN
cord-257662-viy65y72	126	59	(	(	-LRB-
cord-257662-viy65y72	126	60	51	51	CD
cord-257662-viy65y72	126	61	)	)	-RRB-
cord-257662-viy65y72	126	62	.	.	.
cord-257662-viy65y72	127	1	Influenza	influenza	NN
cord-257662-viy65y72	127	2	infection	infection	NN
cord-257662-viy65y72	127	3	in	in	IN
cord-257662-viy65y72	127	4	vitro	vitro	FW
cord-257662-viy65y72	127	5	was	be	VBD
cord-257662-viy65y72	127	6	shown	show	VBN
cord-257662-viy65y72	127	7	to	to	TO
cord-257662-viy65y72	127	8	induce	induce	VB
cord-257662-viy65y72	127	9	apoptosis	apoptosis	NN
cord-257662-viy65y72	127	10	,	,	,
cord-257662-viy65y72	127	11	and	and	CC
cord-257662-viy65y72	127	12	a	a	DT
cord-257662-viy65y72	127	13	reduction	reduction	NN
cord-257662-viy65y72	127	14	in	in	IN
cord-257662-viy65y72	127	15	influenza	influenza	NN
cord-257662-viy65y72	127	16	-	-	HYPH
cord-257662-viy65y72	127	17	mediated	mediate	VBN
cord-257662-viy65y72	127	18	apoptosis	apoptosis	NN
cord-257662-viy65y72	127	19	was	be	VBD
cord-257662-viy65y72	127	20	noted	note	VBN
cord-257662-viy65y72	127	21	in	in	IN
cord-257662-viy65y72	127	22	cells	cell	NNS
cord-257662-viy65y72	127	23	treated	treat	VBN
cord-257662-viy65y72	127	24	with	with	IN
cord-257662-viy65y72	127	25	a	a	DT
cord-257662-viy65y72	127	26	NOS	NOS	NNP
cord-257662-viy65y72	127	27	inhibitor	inhibitor	NN
cord-257662-viy65y72	127	28	(	(	-LRB-
cord-257662-viy65y72	127	29	52	52	CD
cord-257662-viy65y72	127	30	)	)	-RRB-
cord-257662-viy65y72	127	31	.	.	.
cord-257662-viy65y72	128	1	Similarly	similarly	RB
cord-257662-viy65y72	128	2	,	,	,
cord-257662-viy65y72	128	3	fewer	few	JJR
cord-257662-viy65y72	128	4	apoptotic	apoptotic	JJ
cord-257662-viy65y72	128	5	cells	cell	NNS
cord-257662-viy65y72	128	6	were	be	VBD
cord-257662-viy65y72	128	7	found	find	VBN
cord-257662-viy65y72	128	8	in	in	IN
cord-257662-viy65y72	128	9	the	the	DT
cord-257662-viy65y72	128	10	lungs	lung	NNS
cord-257662-viy65y72	128	11	of	of	IN
cord-257662-viy65y72	128	12	influenza	influenza	NN
cord-257662-viy65y72	128	13	-	-	HYPH
cord-257662-viy65y72	128	14	infected	infect	VBN
cord-257662-viy65y72	128	15	Nos2	Nos2	NNP
cord-257662-viy65y72	128	16	−/−	−/−	NNP
cord-257662-viy65y72	128	17	mice	mouse	NNS
cord-257662-viy65y72	128	18	,	,	,
cord-257662-viy65y72	128	19	suggesting	suggest	VBG
cord-257662-viy65y72	128	20	that	that	IN
cord-257662-viy65y72	128	21	NO	no	DT
cord-257662-viy65y72	128	22	mediates	mediate	VBZ
cord-257662-viy65y72	128	23	cell	cell	NN
cord-257662-viy65y72	128	24	death	death	NN
cord-257662-viy65y72	128	25	following	follow	VBG
cord-257662-viy65y72	128	26	influenza	influenza	NN
cord-257662-viy65y72	128	27	infection	infection	NN
cord-257662-viy65y72	128	28	(	(	-LRB-
cord-257662-viy65y72	128	29	52	52	CD
cord-257662-viy65y72	128	30	)	)	-RRB-
cord-257662-viy65y72	128	31	.	.	.
cord-257662-viy65y72	129	1	The	the	DT
cord-257662-viy65y72	129	2	cellular	cellular	JJ
cord-257662-viy65y72	129	3	source	source	NN
cord-257662-viy65y72	129	4	of	of	IN
cord-257662-viy65y72	129	5	iNOS/	iNOS/	.
cord-257662-viy65y72	130	1	NO	no	DT
cord-257662-viy65y72	130	2	following	follow	VBG
cord-257662-viy65y72	130	3	influenza	influenza	NN
cord-257662-viy65y72	130	4	infection	infection	NN
cord-257662-viy65y72	130	5	in	in	IN
cord-257662-viy65y72	130	6	mice	mouse	NNS
cord-257662-viy65y72	130	7	was	be	VBD
cord-257662-viy65y72	130	8	shown	show	VBN
cord-257662-viy65y72	130	9	to	to	TO
cord-257662-viy65y72	130	10	be	be	VB
cord-257662-viy65y72	130	11	CCR2	CCR2	NNP
cord-257662-viy65y72	130	12	+	+	CC
cord-257662-viy65y72	130	13	inflammatory	inflammatory	JJ
cord-257662-viy65y72	130	14	monocytes	monocyte	NNS
cord-257662-viy65y72	130	15	that	that	WDT
cord-257662-viy65y72	130	16	accumulate	accumulate	VBP
cord-257662-viy65y72	130	17	in	in	IN
cord-257662-viy65y72	130	18	the	the	DT
cord-257662-viy65y72	130	19	lungs	lung	NNS
cord-257662-viy65y72	130	20	:	:	:
cord-257662-viy65y72	131	1	CCR2	CCR2	NNP
cord-257662-viy65y72	131	2	−/−	−/−	NNP
cord-257662-viy65y72	132	1	mice	mouse	NNS
cord-257662-viy65y72	132	2	survived	survive	VBD
cord-257662-viy65y72	132	3	a	a	DT
cord-257662-viy65y72	132	4	lethal	lethal	JJ
cord-257662-viy65y72	132	5	challenge	challenge	NN
cord-257662-viy65y72	132	6	of	of	IN
cord-257662-viy65y72	132	7	influenza	influenza	NN
cord-257662-viy65y72	132	8	infection	infection	NN
cord-257662-viy65y72	132	9	(	(	-LRB-
cord-257662-viy65y72	132	10	PR/8/34	pr/8/34	CD
cord-257662-viy65y72	132	11	strain	strain	NN
cord-257662-viy65y72	132	12	)	)	-RRB-
cord-257662-viy65y72	132	13	and	and	CC
cord-257662-viy65y72	132	14	had	have	VBD
cord-257662-viy65y72	132	15	significantly	significantly	RB
cord-257662-viy65y72	132	16	reduced	reduce	VBN
cord-257662-viy65y72	132	17	accumulation	accumulation	NN
cord-257662-viy65y72	132	18	of	of	IN
cord-257662-viy65y72	132	19	iNOS	inos	NN
cord-257662-viy65y72	132	20	-	-	HYPH
cord-257662-viy65y72	132	21	expressing	express	VBG
cord-257662-viy65y72	132	22	macrophages	macrophage	NNS
cord-257662-viy65y72	132	23	in	in	IN
cord-257662-viy65y72	132	24	the	the	DT
cord-257662-viy65y72	132	25	lung	lung	NN
cord-257662-viy65y72	132	26	,	,	,
cord-257662-viy65y72	132	27	with	with	IN
cord-257662-viy65y72	132	28	no	no	DT
cord-257662-viy65y72	132	29	associated	associated	JJ
cord-257662-viy65y72	132	30	increase	increase	NN
cord-257662-viy65y72	132	31	in	in	IN
cord-257662-viy65y72	132	32	viral	viral	JJ
cord-257662-viy65y72	132	33	titers	titer	NNS
cord-257662-viy65y72	132	34	or	or	CC
cord-257662-viy65y72	132	35	dissemination	dissemination	NN
cord-257662-viy65y72	132	36	(	(	-LRB-
cord-257662-viy65y72	132	37	53	53	CD
cord-257662-viy65y72	132	38	)	)	-RRB-
cord-257662-viy65y72	132	39	.	.	.
cord-257662-viy65y72	133	1	It	-PRON-	PRP
cord-257662-viy65y72	133	2	was	be	VBD
cord-257662-viy65y72	133	3	also	also	RB
cord-257662-viy65y72	133	4	recently	recently	RB
cord-257662-viy65y72	133	5	shown	show	VBN
cord-257662-viy65y72	133	6	that	that	IN
cord-257662-viy65y72	133	7	a	a	DT
cord-257662-viy65y72	133	8	subset	subset	NN
cord-257662-viy65y72	133	9	of	of	IN
cord-257662-viy65y72	133	10	monocyte	monocyte	NN
cord-257662-viy65y72	133	11	-	-	HYPH
cord-257662-viy65y72	133	12	derived	derive	VBN
cord-257662-viy65y72	133	13	dendritic	dendritic	JJ
cord-257662-viy65y72	133	14	cells	cell	NNS
cord-257662-viy65y72	133	15	(	(	-LRB-
cord-257662-viy65y72	133	16	DCs	DCs	NNP
cord-257662-viy65y72	133	17	)	)	-RRB-
cord-257662-viy65y72	133	18	,	,	,
cord-257662-viy65y72	133	19	described	describe	VBN
cord-257662-viy65y72	133	20	as	as	IN
cord-257662-viy65y72	133	21	TNF	TNF	NNP
cord-257662-viy65y72	133	22	-	-	HYPH
cord-257662-viy65y72	133	23	α	α	NNP
cord-257662-viy65y72	133	24	/	/	SYM
cord-257662-viy65y72	133	25	iNOS	inos	CD
cord-257662-viy65y72	133	26	-	-	HYPH
cord-257662-viy65y72	133	27	producing	produce	VBG
cord-257662-viy65y72	133	28	DCs	dc	NNS
cord-257662-viy65y72	133	29	(	(	-LRB-
cord-257662-viy65y72	133	30	tipDCs	tipDCs	NNP
cord-257662-viy65y72	133	31	)	)	-RRB-
cord-257662-viy65y72	133	32	,	,	,
cord-257662-viy65y72	133	33	accumulate	accumulate	VBP
cord-257662-viy65y72	133	34	in	in	IN
cord-257662-viy65y72	133	35	greater	great	JJR
cord-257662-viy65y72	133	36	numbers	number	NNS
cord-257662-viy65y72	133	37	during	during	IN
cord-257662-viy65y72	133	38	the	the	DT
cord-257662-viy65y72	133	39	course	course	NN
cord-257662-viy65y72	133	40	of	of	IN
cord-257662-viy65y72	133	41	lethal	lethal	JJ
cord-257662-viy65y72	133	42	versus	versus	IN
cord-257662-viy65y72	133	43	sublethal	sublethal	JJ
cord-257662-viy65y72	133	44	influenza	influenza	NN
cord-257662-viy65y72	133	45	infections	infection	NNS
cord-257662-viy65y72	133	46	,	,	,
cord-257662-viy65y72	133	47	suggesting	suggest	VBG
cord-257662-viy65y72	133	48	a	a	DT
cord-257662-viy65y72	133	49	pathogenic	pathogenic	JJ
cord-257662-viy65y72	133	50	role	role	NN
cord-257662-viy65y72	133	51	for	for	IN
cord-257662-viy65y72	133	52	this	this	DT
cord-257662-viy65y72	133	53	subpopulation	subpopulation	NN
cord-257662-viy65y72	133	54	of	of	IN
cord-257662-viy65y72	133	55	myeloid	myeloid	NN
cord-257662-viy65y72	133	56	cells	cell	NNS
cord-257662-viy65y72	133	57	(	(	-LRB-
cord-257662-viy65y72	133	58	54	54	CD
cord-257662-viy65y72	133	59	)	)	-RRB-
cord-257662-viy65y72	133	60	.	.	.
cord-257662-viy65y72	134	1	Interestingly	interestingly	RB
cord-257662-viy65y72	134	2	,	,	,
cord-257662-viy65y72	134	3	though	though	RB
cord-257662-viy65y72	134	4	,	,	,
cord-257662-viy65y72	134	5	Aldridge	Aldridge	NNP
cord-257662-viy65y72	134	6	et	et	NNP
cord-257662-viy65y72	134	7	al	al	NNP
cord-257662-viy65y72	134	8	.	.	.
cord-257662-viy65y72	135	1	(	(	-LRB-
cord-257662-viy65y72	135	2	54	54	CD
cord-257662-viy65y72	135	3	)	)	-RRB-
cord-257662-viy65y72	135	4	found	find	VBD
cord-257662-viy65y72	135	5	that	that	IN
cord-257662-viy65y72	135	6	the	the	DT
cord-257662-viy65y72	135	7	tipDCs	tipdcs	NN
cord-257662-viy65y72	135	8	also	also	RB
cord-257662-viy65y72	135	9	stimulated	stimulate	VBD
cord-257662-viy65y72	135	10	a	a	DT
cord-257662-viy65y72	135	11	local	local	JJ
cord-257662-viy65y72	135	12	,	,	,
cord-257662-viy65y72	135	13	protective	protective	JJ
cord-257662-viy65y72	135	14	CD8	CD8	NNP
cord-257662-viy65y72	135	15	+	+	CC
cord-257662-viy65y72	135	16	T	T	NNP
cord-257662-viy65y72	135	17	cell	cell	NN
cord-257662-viy65y72	135	18	response	response	NN
cord-257662-viy65y72	135	19	in	in	IN
cord-257662-viy65y72	135	20	the	the	DT
cord-257662-viy65y72	135	21	virusinfected	virusinfected	JJ
cord-257662-viy65y72	135	22	respiratory	respiratory	JJ
cord-257662-viy65y72	135	23	tract	tract	NN
cord-257662-viy65y72	135	24	,	,	,
cord-257662-viy65y72	135	25	indicating	indicate	VBG
cord-257662-viy65y72	135	26	both	both	CC
cord-257662-viy65y72	135	27	protective	protective	JJ
cord-257662-viy65y72	135	28	and	and	CC
cord-257662-viy65y72	135	29	pathogenic	pathogenic	JJ
cord-257662-viy65y72	135	30	roles	role	NNS
cord-257662-viy65y72	135	31	for	for	IN
cord-257662-viy65y72	135	32	these	these	DT
cord-257662-viy65y72	135	33	cells	cell	NNS
cord-257662-viy65y72	135	34	in	in	IN
cord-257662-viy65y72	135	35	influenza	influenza	NN
cord-257662-viy65y72	135	36	infection	infection	NN
cord-257662-viy65y72	135	37	.	.	.
cord-257662-viy65y72	136	1	It	-PRON-	PRP
cord-257662-viy65y72	136	2	was	be	VBD
cord-257662-viy65y72	136	3	further	further	RB
cord-257662-viy65y72	136	4	shown	show	VBN
cord-257662-viy65y72	136	5	that	that	WDT
cord-257662-viy65y72	136	6	partially	partially	RB
cord-257662-viy65y72	136	7	compromising	compromise	VBG
cord-257662-viy65y72	136	8	tipDC	tipdc	JJ
cord-257662-viy65y72	136	9	recruitment	recruitment	NN
cord-257662-viy65y72	136	10	via	via	IN
cord-257662-viy65y72	136	11	treatment	treatment	NN
cord-257662-viy65y72	136	12	with	with	IN
cord-257662-viy65y72	136	13	pioglitazone	pioglitazone	NN
cord-257662-viy65y72	136	14	,	,	,
cord-257662-viy65y72	136	15	a	a	DT
cord-257662-viy65y72	136	16	synthetic	synthetic	JJ
cord-257662-viy65y72	136	17	agonist	agonist	NN
cord-257662-viy65y72	136	18	of	of	IN
cord-257662-viy65y72	136	19	the	the	DT
cord-257662-viy65y72	136	20	peroxisome	peroxisome	NN
cord-257662-viy65y72	136	21	proliferator	proliferator	NN
cord-257662-viy65y72	136	22	-	-	HYPH
cord-257662-viy65y72	136	23	activated	activate	VBN
cord-257662-viy65y72	136	24	receptor	receptor	NN
cord-257662-viy65y72	136	25	-	-	HYPH
cord-257662-viy65y72	136	26	γ	γ	NN
cord-257662-viy65y72	136	27	(	(	-LRB-
cord-257662-viy65y72	136	28	PPAR	PPAR	NNP
cord-257662-viy65y72	136	29	-	-	HYPH
cord-257662-viy65y72	136	30	γ	γ	NNP
cord-257662-viy65y72	136	31	)	)	-RRB-
cord-257662-viy65y72	136	32	,	,	,
cord-257662-viy65y72	136	33	was	be	VBD
cord-257662-viy65y72	136	34	protective	protective	JJ
cord-257662-viy65y72	136	35	against	against	IN
cord-257662-viy65y72	136	36	lethal	lethal	JJ
cord-257662-viy65y72	136	37	influenza	influenza	NN
cord-257662-viy65y72	136	38	challenge	challenge	NN
cord-257662-viy65y72	136	39	(	(	-LRB-
cord-257662-viy65y72	136	40	54	54	CD
cord-257662-viy65y72	136	41	)	)	-RRB-
cord-257662-viy65y72	136	42	.	.	.
cord-257662-viy65y72	137	1	Pioglitazone	pioglitazone	NN
cord-257662-viy65y72	137	2	treatment	treatment	NN
cord-257662-viy65y72	137	3	led	lead	VBD
cord-257662-viy65y72	137	4	to	to	IN
cord-257662-viy65y72	137	5	a	a	DT
cord-257662-viy65y72	137	6	reduction	reduction	NN
cord-257662-viy65y72	137	7	in	in	IN
cord-257662-viy65y72	137	8	the	the	DT
cord-257662-viy65y72	137	9	levels	level	NNS
cord-257662-viy65y72	137	10	of	of	IN
cord-257662-viy65y72	137	11	CCL2	CCL2	NNP
cord-257662-viy65y72	137	12	(	(	-LRB-
cord-257662-viy65y72	137	13	MCP-1	MCP-1	NNP
cord-257662-viy65y72	137	14	)	)	-RRB-
cord-257662-viy65y72	137	15	and	and	CC
cord-257662-viy65y72	137	16	MCP-3	MCP-3	NNP
cord-257662-viy65y72	137	17	in	in	IN
cord-257662-viy65y72	137	18	the	the	DT
cord-257662-viy65y72	137	19	BAL	bal	NN
cord-257662-viy65y72	137	20	fluid	fluid	NN
cord-257662-viy65y72	137	21	of	of	IN
cord-257662-viy65y72	137	22	influenza	influenza	NN
cord-257662-viy65y72	137	23	-	-	HYPH
cord-257662-viy65y72	137	24	infected	infect	VBN
cord-257662-viy65y72	137	25	mice	mouse	NNS
cord-257662-viy65y72	137	26	(	(	-LRB-
cord-257662-viy65y72	137	27	54	54	CD
cord-257662-viy65y72	137	28	)	)	-RRB-
cord-257662-viy65y72	137	29	.	.	.
cord-257662-viy65y72	138	1	Pioglitazone	Pioglitazone	NNP
cord-257662-viy65y72	138	2	has	have	VBZ
cord-257662-viy65y72	138	3	also	also	RB
cord-257662-viy65y72	138	4	been	be	VBN
cord-257662-viy65y72	138	5	shown	show	VBN
cord-257662-viy65y72	138	6	to	to	TO
cord-257662-viy65y72	138	7	reduce	reduce	VB
cord-257662-viy65y72	138	8	the	the	DT
cord-257662-viy65y72	138	9	production	production	NN
cord-257662-viy65y72	138	10	of	of	IN
cord-257662-viy65y72	138	11	a	a	DT
cord-257662-viy65y72	138	12	wide	wide	JJ
cord-257662-viy65y72	138	13	range	range	NN
cord-257662-viy65y72	138	14	of	of	IN
cord-257662-viy65y72	138	15	proinflammatory	proinflammatory	JJ
cord-257662-viy65y72	138	16	molecules	molecule	NNS
cord-257662-viy65y72	138	17	,	,	,
cord-257662-viy65y72	138	18	including	include	VBG
cord-257662-viy65y72	138	19	iNOS	inos	JJ
cord-257662-viy65y72	138	20	(	(	-LRB-
cord-257662-viy65y72	138	21	55	55	CD
cord-257662-viy65y72	138	22	)	)	-RRB-
cord-257662-viy65y72	138	23	,	,	,
cord-257662-viy65y72	138	24	providing	provide	VBG
cord-257662-viy65y72	138	25	further	further	JJ
cord-257662-viy65y72	138	26	evidence	evidence	NN
cord-257662-viy65y72	138	27	for	for	IN
cord-257662-viy65y72	138	28	the	the	DT
cord-257662-viy65y72	138	29	importance	importance	NN
cord-257662-viy65y72	138	30	of	of	IN
cord-257662-viy65y72	138	31	NO	no	DT
cord-257662-viy65y72	138	32	production	production	NN
cord-257662-viy65y72	138	33	by	by	IN
cord-257662-viy65y72	138	34	monocyte	monocyte	NNP
cord-257662-viy65y72	138	35	-	-	HYPH
cord-257662-viy65y72	138	36	derived	derive	VBN
cord-257662-viy65y72	138	37	cells	cell	NNS
cord-257662-viy65y72	138	38	in	in	IN
cord-257662-viy65y72	138	39	the	the	DT
cord-257662-viy65y72	138	40	pathogenesis	pathogenesis	NN
cord-257662-viy65y72	138	41	of	of	IN
cord-257662-viy65y72	138	42	influenza	influenza	NN
cord-257662-viy65y72	138	43	infection	infection	NN
cord-257662-viy65y72	138	44	.	.	.
cord-257662-viy65y72	139	1	Pharmacologic	Pharmacologic	NNP
cord-257662-viy65y72	139	2	inhibition	inhibition	NN
cord-257662-viy65y72	139	3	of	of	IN
cord-257662-viy65y72	139	4	NOS	NOS	NNP
cord-257662-viy65y72	139	5	using	use	VBG
cord-257662-viy65y72	139	6	l	l	NNP
cord-257662-viy65y72	139	7	-	-	HYPH
cord-257662-viy65y72	139	8	NMMA	NMMA	NNP
cord-257662-viy65y72	139	9	also	also	RB
cord-257662-viy65y72	139	10	decreased	decrease	VBD
cord-257662-viy65y72	139	11	pneumonitis	pneumonitis	NN
cord-257662-viy65y72	139	12	and	and	CC
cord-257662-viy65y72	139	13	increased	increase	VBN
cord-257662-viy65y72	139	14	survival	survival	NN
cord-257662-viy65y72	139	15	following	follow	VBG
cord-257662-viy65y72	139	16	intranasal	intranasal	NN
cord-257662-viy65y72	139	17	infection	infection	NN
cord-257662-viy65y72	139	18	of	of	IN
cord-257662-viy65y72	139	19	CBA	CBA	NNP
cord-257662-viy65y72	139	20	/	/	SYM
cord-257662-viy65y72	139	21	J	J	NNP
cord-257662-viy65y72	139	22	mice	mouse	NNS
cord-257662-viy65y72	139	23	with	with	IN
cord-257662-viy65y72	139	24	HSV-1	HSV-1	NNP
cord-257662-viy65y72	139	25	,	,	,
cord-257662-viy65y72	139	26	despite	despite	IN
cord-257662-viy65y72	139	27	a	a	DT
cord-257662-viy65y72	139	28	17-fold	17-fold	JJ
cord-257662-viy65y72	139	29	increase	increase	NN
cord-257662-viy65y72	139	30	in	in	IN
cord-257662-viy65y72	139	31	viral	viral	JJ
cord-257662-viy65y72	139	32	titers	titer	NNS
cord-257662-viy65y72	139	33	in	in	IN
cord-257662-viy65y72	139	34	the	the	DT
cord-257662-viy65y72	139	35	lung	lung	NN
cord-257662-viy65y72	139	36	at	at	IN
cord-257662-viy65y72	139	37	day	day	NN
cord-257662-viy65y72	139	38	3	3	CD
cord-257662-viy65y72	139	39	after	after	IN
cord-257662-viy65y72	139	40	inoculation	inoculation	NN
cord-257662-viy65y72	139	41	(	(	-LRB-
cord-257662-viy65y72	139	42	58	58	CD
cord-257662-viy65y72	139	43	)	)	-RRB-
cord-257662-viy65y72	139	44	.	.	.
cord-257662-viy65y72	140	1	In	in	IN
cord-257662-viy65y72	140	2	contrast	contrast	NN
cord-257662-viy65y72	140	3	,	,	,
cord-257662-viy65y72	140	4	treatment	treatment	NN
cord-257662-viy65y72	140	5	of	of	IN
cord-257662-viy65y72	140	6	BALB	BALB	NNP
cord-257662-viy65y72	140	7	/	/	SYM
cord-257662-viy65y72	140	8	c	c	NN
cord-257662-viy65y72	140	9	mice	mouse	NNS
cord-257662-viy65y72	140	10	with	with	IN
cord-257662-viy65y72	140	11	a	a	DT
cord-257662-viy65y72	140	12	different	different	JJ
cord-257662-viy65y72	140	13	NOS	NOS	NNP
cord-257662-viy65y72	140	14	inhibitor	inhibitor	NN
cord-257662-viy65y72	140	15	[	[	-LRB-
cord-257662-viy65y72	140	16	aminoguanidine	aminoguanidine	NN
cord-257662-viy65y72	140	17	(	(	-LRB-
cord-257662-viy65y72	140	18	AG	AG	NNP
cord-257662-viy65y72	140	19	)	)	-RRB-
cord-257662-viy65y72	140	20	,	,	,
cord-257662-viy65y72	140	21	administered	administer	VBN
cord-257662-viy65y72	140	22	intranasally	intranasally	RB
cord-257662-viy65y72	140	23	]	]	-RRB-
cord-257662-viy65y72	140	24	resulted	result	VBN
cord-257662-viy65y72	140	25	in	in	IN
cord-257662-viy65y72	140	26	enhanced	enhance	VBN
cord-257662-viy65y72	140	27	pneumonitis	pneumonitis	NN
cord-257662-viy65y72	140	28	,	,	,
cord-257662-viy65y72	140	29	viral	viral	JJ
cord-257662-viy65y72	140	30	titers	titer	NNS
cord-257662-viy65y72	140	31	,	,	,
cord-257662-viy65y72	140	32	and	and	CC
cord-257662-viy65y72	140	33	mortality	mortality	NN
cord-257662-viy65y72	140	34	following	follow	VBG
cord-257662-viy65y72	140	35	infection	infection	NN
cord-257662-viy65y72	140	36	with	with	IN
cord-257662-viy65y72	140	37	a	a	DT
cord-257662-viy65y72	140	38	different	different	JJ
cord-257662-viy65y72	140	39	strain	strain	NN
cord-257662-viy65y72	140	40	of	of	IN
cord-257662-viy65y72	140	41	HSV-1	hsv-1	NN
cord-257662-viy65y72	140	42	(	(	-LRB-
cord-257662-viy65y72	140	43	59	59	CD
cord-257662-viy65y72	140	44	)	)	-RRB-
cord-257662-viy65y72	140	45	.	.	.
cord-257662-viy65y72	141	1	Thus	thus	RB
cord-257662-viy65y72	141	2	,	,	,
cord-257662-viy65y72	141	3	the	the	DT
cord-257662-viy65y72	141	4	precise	precise	JJ
cord-257662-viy65y72	141	5	role	role	NN
cord-257662-viy65y72	141	6	of	of	IN
cord-257662-viy65y72	141	7	NO	no	DT
cord-257662-viy65y72	141	8	in	in	IN
cord-257662-viy65y72	141	9	HSV-1	hsv-1	NN
cord-257662-viy65y72	141	10	pneumonitis	pneumonitis	NN
cord-257662-viy65y72	141	11	remains	remain	VBZ
cord-257662-viy65y72	141	12	to	to	TO
cord-257662-viy65y72	141	13	be	be	VB
cord-257662-viy65y72	141	14	determined	determine	VBN
cord-257662-viy65y72	141	15	.	.	.
cord-257662-viy65y72	142	1	NO	no	UH
cord-257662-viy65y72	142	2	and	and	CC
cord-257662-viy65y72	142	3	other	other	JJ
cord-257662-viy65y72	142	4	ROS	ROS	NNP
cord-257662-viy65y72	142	5	/	/	SYM
cord-257662-viy65y72	142	6	RNS	RNS	NNP
cord-257662-viy65y72	142	7	were	be	VBD
cord-257662-viy65y72	142	8	also	also	RB
cord-257662-viy65y72	142	9	shown	show	VBN
cord-257662-viy65y72	142	10	to	to	TO
cord-257662-viy65y72	142	11	be	be	VB
cord-257662-viy65y72	142	12	pathogenic	pathogenic	JJ
cord-257662-viy65y72	142	13	in	in	IN
cord-257662-viy65y72	142	14	the	the	DT
cord-257662-viy65y72	142	15	brains	brain	NNS
cord-257662-viy65y72	142	16	of	of	IN
cord-257662-viy65y72	142	17	mice	mouse	NNS
cord-257662-viy65y72	142	18	with	with	IN
cord-257662-viy65y72	142	19	herpes	herpes	NNP
cord-257662-viy65y72	142	20	encephalitis	encephalitis	RB
cord-257662-viy65y72	142	21	:	:	:
cord-257662-viy65y72	142	22	iNOS	iNOS	NNP
cord-257662-viy65y72	142	23	was	be	VBD
cord-257662-viy65y72	142	24	induced	induce	VBN
cord-257662-viy65y72	142	25	in	in	IN
cord-257662-viy65y72	142	26	CD11b	CD11b	NNS
cord-257662-viy65y72	142	27	+	+	CC
cord-257662-viy65y72	142	28	resident	resident	NN
cord-257662-viy65y72	142	29	microglia	microglia	NNS
cord-257662-viy65y72	142	30	following	follow	VBG
cord-257662-viy65y72	142	31	intranasal	intranasal	NN
cord-257662-viy65y72	142	32	infection	infection	NN
cord-257662-viy65y72	142	33	with	with	IN
cord-257662-viy65y72	142	34	HSV-1	HSV-1	NNP
cord-257662-viy65y72	142	35	,	,	,
cord-257662-viy65y72	142	36	and	and	CC
cord-257662-viy65y72	143	1	oxidative	oxidative	JJ
cord-257662-viy65y72	143	2	and	and	CC
cord-257662-viy65y72	143	3	nitrative	nitrative	JJ
cord-257662-viy65y72	143	4	damage	damage	NN
cord-257662-viy65y72	143	5	was	be	VBD
cord-257662-viy65y72	143	6	found	find	VBN
cord-257662-viy65y72	143	7	in	in	IN
cord-257662-viy65y72	143	8	the	the	DT
cord-257662-viy65y72	143	9	brains	brain	NNS
cord-257662-viy65y72	143	10	of	of	IN
cord-257662-viy65y72	143	11	infected	infected	JJ
cord-257662-viy65y72	143	12	animals	animal	NNS
cord-257662-viy65y72	143	13	(	(	-LRB-
cord-257662-viy65y72	143	14	60	60	CD
cord-257662-viy65y72	143	15	)	)	-RRB-
cord-257662-viy65y72	143	16	.	.	.
cord-257662-viy65y72	144	1	A	a	DT
cord-257662-viy65y72	144	2	common	common	JJ
cord-257662-viy65y72	144	3	neurological	neurological	JJ
cord-257662-viy65y72	144	4	complication	complication	NN
cord-257662-viy65y72	144	5	of	of	IN
cord-257662-viy65y72	144	6	HIV	HIV	NNP
cord-257662-viy65y72	144	7	infection	infection	NN
cord-257662-viy65y72	144	8	in	in	IN
cord-257662-viy65y72	144	9	the	the	DT
cord-257662-viy65y72	144	10	developed	develop	VBN
cord-257662-viy65y72	144	11	world	world	NN
cord-257662-viy65y72	144	12	is	be	VBZ
cord-257662-viy65y72	144	13	sensory	sensory	JJ
cord-257662-viy65y72	144	14	neuronal	neuronal	JJ
cord-257662-viy65y72	144	15	injury	injury	NN
cord-257662-viy65y72	144	16	accompanied	accompany	VBN
cord-257662-viy65y72	144	17	by	by	IN
cord-257662-viy65y72	144	18	inflammation	inflammation	NN
cord-257662-viy65y72	144	19	,	,	,
cord-257662-viy65y72	144	20	which	which	WDT
cord-257662-viy65y72	144	21	is	be	VBZ
cord-257662-viy65y72	144	22	clinically	clinically	RB
cord-257662-viy65y72	144	23	manifested	manifest	VBN
cord-257662-viy65y72	144	24	as	as	IN
cord-257662-viy65y72	144	25	disabling	disable	VBG
cord-257662-viy65y72	144	26	pain	pain	NN
cord-257662-viy65y72	144	27	and	and	CC
cord-257662-viy65y72	144	28	gait	gait	JJ
cord-257662-viy65y72	144	29	instability	instability	NN
cord-257662-viy65y72	144	30	.	.	.
cord-257662-viy65y72	145	1	Feline	feline	JJ
cord-257662-viy65y72	145	2	immunodeficiency	immunodeficiency	NN
cord-257662-viy65y72	145	3	virus	virus	NN
cord-257662-viy65y72	145	4	(	(	-LRB-
cord-257662-viy65y72	145	5	FIV	fiv	NN
cord-257662-viy65y72	145	6	)	)	-RRB-
cord-257662-viy65y72	145	7	infection	infection	NN
cord-257662-viy65y72	145	8	of	of	IN
cord-257662-viy65y72	145	9	cats	cat	NNS
cord-257662-viy65y72	145	10	,	,	,
cord-257662-viy65y72	145	11	which	which	WDT
cord-257662-viy65y72	145	12	causes	cause	VBZ
cord-257662-viy65y72	145	13	similar	similar	JJ
cord-257662-viy65y72	145	14	neuroinflammation	neuroinflammation	NN
cord-257662-viy65y72	145	15	together	together	RB
cord-257662-viy65y72	145	16	with	with	IN
cord-257662-viy65y72	145	17	immunosuppression	immunosuppression	NN
cord-257662-viy65y72	145	18	in	in	IN
cord-257662-viy65y72	145	19	cats	cat	NNS
cord-257662-viy65y72	145	20	,	,	,
cord-257662-viy65y72	145	21	resulted	result	VBD
cord-257662-viy65y72	145	22	in	in	IN
cord-257662-viy65y72	145	23	induction	induction	NN
cord-257662-viy65y72	145	24	of	of	IN
cord-257662-viy65y72	145	25	iNOS	inos	NN
cord-257662-viy65y72	145	26	and	and	CC
cord-257662-viy65y72	145	27	STAT-1	STAT-1	NNS
cord-257662-viy65y72	145	28	,	,	,
cord-257662-viy65y72	145	29	which	which	WDT
cord-257662-viy65y72	145	30	were	be	VBD
cord-257662-viy65y72	145	31	predominantly	predominantly	RB
cord-257662-viy65y72	145	32	produced	produce	VBN
cord-257662-viy65y72	145	33	by	by	IN
cord-257662-viy65y72	145	34	macrophages	macrophage	NNS
cord-257662-viy65y72	145	35	,	,	,
cord-257662-viy65y72	145	36	in	in	IN
cord-257662-viy65y72	145	37	DRG	DRG	NNP
cord-257662-viy65y72	145	38	(	(	-LRB-
cord-257662-viy65y72	145	39	64	64	CD
cord-257662-viy65y72	145	40	)	)	-RRB-
cord-257662-viy65y72	145	41	.	.	.
cord-257662-viy65y72	146	1	Additionally	additionally	RB
cord-257662-viy65y72	146	2	,	,	,
cord-257662-viy65y72	146	3	inhibition	inhibition	NN
cord-257662-viy65y72	146	4	of	of	IN
cord-257662-viy65y72	146	5	NOS	NOS	NNP
cord-257662-viy65y72	146	6	resulted	result	VBD
cord-257662-viy65y72	146	7	in	in	IN
cord-257662-viy65y72	146	8	reduced	reduce	VBN
cord-257662-viy65y72	146	9	nitrotyrosine	nitrotyrosine	NN
cord-257662-viy65y72	146	10	and	and	CC
cord-257662-viy65y72	146	11	prevented	prevent	VBD
cord-257662-viy65y72	146	12	neuronal	neuronal	JJ
cord-257662-viy65y72	146	13	injury	injury	NN
cord-257662-viy65y72	146	14	in	in	IN
cord-257662-viy65y72	146	15	FIV	FIV	NNP
cord-257662-viy65y72	146	16	-	-	HYPH
cord-257662-viy65y72	146	17	infected	infect	VBN
cord-257662-viy65y72	146	18	DRG	DRG	NNP
cord-257662-viy65y72	146	19	cultures	culture	NNS
cord-257662-viy65y72	146	20	in	in	IN
cord-257662-viy65y72	146	21	vitro	vitro	FW
cord-257662-viy65y72	146	22	(	(	-LRB-
cord-257662-viy65y72	146	23	64	64	CD
cord-257662-viy65y72	146	24	)	)	-RRB-
cord-257662-viy65y72	146	25	.	.	.
cord-257662-viy65y72	147	1	These	these	DT
cord-257662-viy65y72	147	2	data	datum	NNS
cord-257662-viy65y72	147	3	suggest	suggest	VBP
cord-257662-viy65y72	147	4	that	that	IN
cord-257662-viy65y72	147	5	lentivirus	lentivirus	NN
cord-257662-viy65y72	147	6	infection	infection	NN
cord-257662-viy65y72	147	7	contributes	contribute	VBZ
cord-257662-viy65y72	147	8	to	to	IN
cord-257662-viy65y72	147	9	axonal	axonal	JJ
cord-257662-viy65y72	147	10	and	and	CC
cord-257662-viy65y72	147	11	neuronal	neuronal	JJ
cord-257662-viy65y72	147	12	injury	injury	NN
cord-257662-viy65y72	147	13	through	through	IN
cord-257662-viy65y72	147	14	a	a	DT
cord-257662-viy65y72	147	15	mechanism	mechanism	NN
cord-257662-viy65y72	147	16	involving	involve	VBG
cord-257662-viy65y72	147	17	M1	M1	NNP
cord-257662-viy65y72	147	18	macrophage	macrophage	NN
cord-257662-viy65y72	147	19	immune	immune	JJ
cord-257662-viy65y72	147	20	activation	activation	NN
cord-257662-viy65y72	147	21	mediated	mediate	VBN
cord-257662-viy65y72	147	22	by	by	IN
cord-257662-viy65y72	147	23	STAT-1	STAT-1	NNS
cord-257662-viy65y72	147	24	and	and	CC
cord-257662-viy65y72	147	25	iNOS	inos	JJ
cord-257662-viy65y72	147	26	activation	activation	NN
cord-257662-viy65y72	147	27	.	.	.
cord-257662-viy65y72	148	1	In	in	IN
cord-257662-viy65y72	148	2	addition	addition	NN
cord-257662-viy65y72	148	3	to	to	IN
cord-257662-viy65y72	148	4	these	these	DT
cord-257662-viy65y72	148	5	studies	study	NNS
cord-257662-viy65y72	148	6	,	,	,
cord-257662-viy65y72	148	7	infection	infection	NN
cord-257662-viy65y72	148	8	of	of	IN
cord-257662-viy65y72	148	9	mice	mouse	NNS
cord-257662-viy65y72	148	10	with	with	IN
cord-257662-viy65y72	148	11	the	the	DT
cord-257662-viy65y72	148	12	retrovirus	retrovirus	NN
cord-257662-viy65y72	148	13	LP	LP	NNP
cord-257662-viy65y72	148	14	-	-	HYPH
cord-257662-viy65y72	148	15	BM5	BM5	NNP
cord-257662-viy65y72	148	16	,	,	,
cord-257662-viy65y72	148	17	which	which	WDT
cord-257662-viy65y72	148	18	causes	cause	VBZ
cord-257662-viy65y72	148	19	profound	profound	JJ
cord-257662-viy65y72	148	20	immunodeficiency	immunodeficiency	NN
cord-257662-viy65y72	148	21	,	,	,
cord-257662-viy65y72	148	22	induces	induce	VBZ
cord-257662-viy65y72	148	23	CD11b	CD11b	NNS
cord-257662-viy65y72	148	24	+	+	CC
cord-257662-viy65y72	149	1	GR-1	GR-1	NNP
cord-257662-viy65y72	150	1	+	+	CC
cord-257662-viy65y72	151	1	Ly-6C	Ly-6C	NNP
cord-257662-viy65y72	151	2	+	+	CC
cord-257662-viy65y72	151	3	MDSC	MDSC	NNP
cord-257662-viy65y72	151	4	-	-	HYPH
cord-257662-viy65y72	151	5	like	like	JJ
cord-257662-viy65y72	151	6	cells	cell	NNS
cord-257662-viy65y72	151	7	that	that	WDT
cord-257662-viy65y72	151	8	inhibit	inhibit	VBP
cord-257662-viy65y72	151	9	both	both	DT
cord-257662-viy65y72	151	10	T	t	NN
cord-257662-viy65y72	151	11	-	-	HYPH
cord-257662-viy65y72	151	12	and	and	CC
cord-257662-viy65y72	151	13	B	b	NN
cord-257662-viy65y72	151	14	-	-	HYPH
cord-257662-viy65y72	151	15	cell	cell	NN
cord-257662-viy65y72	151	16	responses	response	NNS
cord-257662-viy65y72	151	17	in	in	IN
cord-257662-viy65y72	151	18	an	an	DT
cord-257662-viy65y72	151	19	iNOS	inos	JJ
cord-257662-viy65y72	151	20	/	/	SYM
cord-257662-viy65y72	151	21	NO	no	NN
cord-257662-viy65y72	151	22	-	-	HYPH
cord-257662-viy65y72	151	23	dependent	dependent	JJ
cord-257662-viy65y72	151	24	but	but	CC
cord-257662-viy65y72	151	25	arginase	arginase	JJ
cord-257662-viy65y72	151	26	-	-	HYPH
cord-257662-viy65y72	151	27	independent	independent	JJ
cord-257662-viy65y72	151	28	fashion	fashion	NN
cord-257662-viy65y72	151	29	(	(	-LRB-
cord-257662-viy65y72	151	30	65	65	CD
cord-257662-viy65y72	151	31	)	)	-RRB-
cord-257662-viy65y72	151	32	.	.	.
cord-257662-viy65y72	152	1	This	this	DT
cord-257662-viy65y72	152	2	study	study	NN
cord-257662-viy65y72	152	3	identified	identify	VBD
cord-257662-viy65y72	152	4	an	an	DT
cord-257662-viy65y72	152	5	important	important	JJ
cord-257662-viy65y72	152	6	-and	-and	:
cord-257662-viy65y72	152	7	only	only	RB
cord-257662-viy65y72	152	8	recently	recently	RB
cord-257662-viy65y72	152	9	appreciated	appreciate	VBN
cord-257662-viy65y72	152	10	-role	-role	NN
cord-257662-viy65y72	152	11	for	for	IN
cord-257662-viy65y72	152	12	iNOSexpressing	inosexpresse	VBG
cord-257662-viy65y72	152	13	myeloid	myeloid	JJ
cord-257662-viy65y72	152	14	cell	cell	NN
cord-257662-viy65y72	152	15	-	-	HYPH
cord-257662-viy65y72	152	16	mediated	mediate	VBN
cord-257662-viy65y72	152	17	suppression	suppression	NN
cord-257662-viy65y72	152	18	of	of	IN
cord-257662-viy65y72	152	19	B	b	NN
cord-257662-viy65y72	152	20	cell	cell	NN
cord-257662-viy65y72	152	21	responses	response	NNS
cord-257662-viy65y72	152	22	in	in	IN
cord-257662-viy65y72	152	23	retrovirus	retrovirus	NN
cord-257662-viy65y72	152	24	infection	infection	NN
cord-257662-viy65y72	152	25	.	.	.
cord-257662-viy65y72	153	1	The	the	DT
cord-257662-viy65y72	153	2	oxidative	oxidative	JJ
cord-257662-viy65y72	153	3	effects	effect	NNS
cord-257662-viy65y72	153	4	of	of	IN
cord-257662-viy65y72	153	5	NO	no	DT
cord-257662-viy65y72	153	6	have	have	VBP
cord-257662-viy65y72	153	7	also	also	RB
cord-257662-viy65y72	153	8	been	be	VBN
cord-257662-viy65y72	153	9	shown	show	VBN
cord-257662-viy65y72	153	10	to	to	TO
cord-257662-viy65y72	153	11	inhibit	inhibit	VB
cord-257662-viy65y72	153	12	immune	immune	JJ
cord-257662-viy65y72	153	13	cells	cell	NNS
cord-257662-viy65y72	153	14	,	,	,
cord-257662-viy65y72	153	15	particularly	particularly	RB
cord-257662-viy65y72	153	16	T	t	NN
cord-257662-viy65y72	153	17	cells	cell	NNS
cord-257662-viy65y72	153	18	.	.	.
cord-257662-viy65y72	154	1	This	this	DT
cord-257662-viy65y72	154	2	phenomenon	phenomenon	NN
cord-257662-viy65y72	154	3	has	have	VBZ
cord-257662-viy65y72	154	4	been	be	VBN
cord-257662-viy65y72	154	5	appreciated	appreciate	VBN
cord-257662-viy65y72	154	6	for	for	IN
cord-257662-viy65y72	154	7	a	a	DT
cord-257662-viy65y72	154	8	number	number	NN
cord-257662-viy65y72	154	9	of	of	IN
cord-257662-viy65y72	154	10	years	year	NNS
cord-257662-viy65y72	154	11	in	in	IN
cord-257662-viy65y72	154	12	the	the	DT
cord-257662-viy65y72	154	13	context	context	NN
cord-257662-viy65y72	154	14	of	of	IN
cord-257662-viy65y72	154	15	tumors	tumor	NNS
cord-257662-viy65y72	154	16	(	(	-LRB-
cord-257662-viy65y72	154	17	92	92	CD
cord-257662-viy65y72	154	18	)	)	-RRB-
cord-257662-viy65y72	154	19	,	,	,
cord-257662-viy65y72	154	20	where	where	WRB
cord-257662-viy65y72	154	21	myeloid	myeloid	JJ
cord-257662-viy65y72	154	22	suppressor	suppressor	NN
cord-257662-viy65y72	154	23	cells	cell	NNS
cord-257662-viy65y72	154	24	can	can	MD
cord-257662-viy65y72	154	25	inhibit	inhibit	VB
cord-257662-viy65y72	154	26	the	the	DT
cord-257662-viy65y72	154	27	anti	anti	JJ
cord-257662-viy65y72	154	28	-	-	JJ
cord-257662-viy65y72	154	29	tumor	tumor	JJ
cord-257662-viy65y72	154	30	T	t	NN
cord-257662-viy65y72	154	31	cell	cell	NN
cord-257662-viy65y72	154	32	response	response	NN
cord-257662-viy65y72	154	33	via	via	IN
cord-257662-viy65y72	154	34	the	the	DT
cord-257662-viy65y72	154	35	effects	effect	NNS
cord-257662-viy65y72	154	36	of	of	IN
cord-257662-viy65y72	154	37	NO	no	NN
cord-257662-viy65y72	154	38	in	in	IN
cord-257662-viy65y72	154	39	addition	addition	NN
cord-257662-viy65y72	154	40	to	to	IN
cord-257662-viy65y72	154	41	other	other	JJ
cord-257662-viy65y72	154	42	mechanisms	mechanism	NNS
cord-257662-viy65y72	154	43	(	(	-LRB-
cord-257662-viy65y72	154	44	2	2	CD
cord-257662-viy65y72	154	45	,	,	,
cord-257662-viy65y72	154	46	4	4	CD
cord-257662-viy65y72	154	47	)	)	-RRB-
cord-257662-viy65y72	154	48	.	.	.
cord-257662-viy65y72	155	1	In	in	IN
cord-257662-viy65y72	155	2	a	a	DT
cord-257662-viy65y72	155	3	similar	similar	JJ
cord-257662-viy65y72	155	4	manner	manner	NN
cord-257662-viy65y72	155	5	,	,	,
cord-257662-viy65y72	155	6	it	-PRON-	PRP
cord-257662-viy65y72	155	7	has	have	VBZ
cord-257662-viy65y72	155	8	been	be	VBN
cord-257662-viy65y72	155	9	shown	show	VBN
cord-257662-viy65y72	155	10	that	that	IN
cord-257662-viy65y72	155	11	NO	no	NN
cord-257662-viy65y72	155	12	can	can	MD
cord-257662-viy65y72	155	13	inhibit	inhibit	VB
cord-257662-viy65y72	155	14	the	the	DT
cord-257662-viy65y72	155	15	antiviral	antiviral	JJ
cord-257662-viy65y72	155	16	immune	immune	JJ
cord-257662-viy65y72	155	17	response	response	NN
cord-257662-viy65y72	155	18	.	.	.
cord-257662-viy65y72	156	1	MCMV	MCMV	NNP
cord-257662-viy65y72	156	2	clearance	clearance	NN
cord-257662-viy65y72	156	3	from	from	IN
cord-257662-viy65y72	156	4	BALB	BALB	NNP
cord-257662-viy65y72	156	5	/	/	SYM
cord-257662-viy65y72	156	6	c	c	NN
cord-257662-viy65y72	156	7	mice	mice	NN
cord-257662-viy65y72	156	8	is	be	VBZ
cord-257662-viy65y72	156	9	predominantly	predominantly	RB
cord-257662-viy65y72	156	10	CD8	CD8	NNP
cord-257662-viy65y72	156	11	+	+	CC
cord-257662-viy65y72	156	12	T	T	NNP
cord-257662-viy65y72	156	13	cell	cell	NN
cord-257662-viy65y72	156	14	-	-	HYPH
cord-257662-viy65y72	156	15	mediated	mediate	VBN
cord-257662-viy65y72	156	16	.	.	.
cord-257662-viy65y72	157	1	A	a	DT
cord-257662-viy65y72	157	2	recent	recent	JJ
cord-257662-viy65y72	157	3	report	report	NN
cord-257662-viy65y72	157	4	showed	show	VBD
cord-257662-viy65y72	157	5	that	that	IN
cord-257662-viy65y72	157	6	MCMV	MCMV	NNP
cord-257662-viy65y72	157	7	infection	infection	NN
cord-257662-viy65y72	157	8	in	in	IN
cord-257662-viy65y72	157	9	BALB	BALB	NNP
cord-257662-viy65y72	157	10	/	/	SYM
cord-257662-viy65y72	157	11	c	c	NN
cord-257662-viy65y72	157	12	mice	mouse	NNS
cord-257662-viy65y72	157	13	induced	induce	VBN
cord-257662-viy65y72	157	14	CD11b	CD11b	NNPS
cord-257662-viy65y72	158	1	+	+	CC
cord-257662-viy65y72	158	2	Ly-6C	ly-6c	NN
cord-257662-viy65y72	159	1	hi	hi	UH
cord-257662-viy65y72	159	2	inflammatory	inflammatory	JJ
cord-257662-viy65y72	159	3	monocyte	monocyte	NNP
cord-257662-viy65y72	159	4	recruitment	recruitment	NN
cord-257662-viy65y72	159	5	from	from	IN
cord-257662-viy65y72	159	6	the	the	DT
cord-257662-viy65y72	159	7	bone	bone	NN
cord-257662-viy65y72	159	8	marrow	marrow	NN
cord-257662-viy65y72	159	9	to	to	IN
cord-257662-viy65y72	159	10	infected	infected	JJ
cord-257662-viy65y72	159	11	tissues	tissue	NNS
cord-257662-viy65y72	159	12	that	that	WDT
cord-257662-viy65y72	159	13	was	be	VBD
cord-257662-viy65y72	159	14	dependent	dependent	JJ
cord-257662-viy65y72	159	15	on	on	IN
cord-257662-viy65y72	159	16	CCR2	CCR2	NNP
cord-257662-viy65y72	159	17	signaling	signaling	NN
cord-257662-viy65y72	159	18	(	(	-LRB-
cord-257662-viy65y72	159	19	66	66	CD
cord-257662-viy65y72	159	20	)	)	-RRB-
cord-257662-viy65y72	159	21	.	.	.
cord-257662-viy65y72	160	1	This	this	DT
cord-257662-viy65y72	160	2	recruitment	recruitment	NN
cord-257662-viy65y72	160	3	was	be	VBD
cord-257662-viy65y72	160	4	shown	show	VBN
cord-257662-viy65y72	160	5	to	to	TO
cord-257662-viy65y72	160	6	inhibit	inhibit	VB
cord-257662-viy65y72	160	7	antigen	antigen	NN
cord-257662-viy65y72	160	8	-	-	HYPH
cord-257662-viy65y72	160	9	specific	specific	JJ
cord-257662-viy65y72	160	10	CD8	CD8	NNP
cord-257662-viy65y72	160	11	+	+	CC
cord-257662-viy65y72	160	12	T	T	NNP
cord-257662-viy65y72	160	13	cell	cell	NN
cord-257662-viy65y72	160	14	activation	activation	NN
cord-257662-viy65y72	160	15	,	,	,
cord-257662-viy65y72	160	16	expansion	expansion	NN
cord-257662-viy65y72	160	17	,	,	,
cord-257662-viy65y72	160	18	and	and	CC
cord-257662-viy65y72	160	19	cytotoxic	cytotoxic	JJ
cord-257662-viy65y72	160	20	activity	activity	NN
cord-257662-viy65y72	160	21	via	via	IN
cord-257662-viy65y72	160	22	NO	no	DT
cord-257662-viy65y72	160	23	production	production	NN
cord-257662-viy65y72	160	24	,	,	,
cord-257662-viy65y72	160	25	thus	thus	RB
cord-257662-viy65y72	160	26	facilitating	facilitate	VBG
cord-257662-viy65y72	160	27	viral	viral	JJ
cord-257662-viy65y72	160	28	persistence	persistence	NN
cord-257662-viy65y72	160	29	(	(	-LRB-
cord-257662-viy65y72	160	30	66	66	CD
cord-257662-viy65y72	160	31	)	)	-RRB-
cord-257662-viy65y72	160	32	.	.	.
cord-257662-viy65y72	161	1	In	in	IN
cord-257662-viy65y72	161	2	a	a	DT
cord-257662-viy65y72	161	3	similar	similar	JJ
cord-257662-viy65y72	161	4	fashion	fashion	NN
cord-257662-viy65y72	161	5	,	,	,
cord-257662-viy65y72	161	6	NO	NO	NNP
cord-257662-viy65y72	161	7	may	may	MD
cord-257662-viy65y72	161	8	contribute	contribute	VB
cord-257662-viy65y72	161	9	to	to	IN
cord-257662-viy65y72	161	10	a	a	DT
cord-257662-viy65y72	161	11	defective	defective	JJ
cord-257662-viy65y72	161	12	immune	immune	JJ
cord-257662-viy65y72	161	13	response	response	NN
cord-257662-viy65y72	161	14	following	follow	VBG
cord-257662-viy65y72	161	15	infection	infection	NN
cord-257662-viy65y72	161	16	of	of	IN
cord-257662-viy65y72	161	17	mice	mouse	NNS
cord-257662-viy65y72	161	18	with	with	IN
cord-257662-viy65y72	161	19	an	an	DT
cord-257662-viy65y72	161	20	attenuated	attenuated	JJ
cord-257662-viy65y72	161	21	neurotropic	neurotropic	JJ
cord-257662-viy65y72	161	22	coronavirus	coronavirus	NN
cord-257662-viy65y72	161	23	(	(	-LRB-
cord-257662-viy65y72	161	24	rJ2.2	rj2.2	CD
cord-257662-viy65y72	161	25	strain	strain	NN
cord-257662-viy65y72	161	26	of	of	IN
cord-257662-viy65y72	161	27	mouse	mouse	NN
cord-257662-viy65y72	161	28	hepatitis	hepatitis	NNP
cord-257662-viy65y72	161	29	virus	virus	NN
cord-257662-viy65y72	161	30	)	)	-RRB-
cord-257662-viy65y72	161	31	.	.	.
cord-257662-viy65y72	162	1	rJ2.2infected	rJ2.2infected	NNP
cord-257662-viy65y72	162	2	WT	WT	NNP
cord-257662-viy65y72	162	3	mice	mouse	NNS
cord-257662-viy65y72	162	4	exhibited	exhibit	VBD
cord-257662-viy65y72	162	5	mild	mild	JJ
cord-257662-viy65y72	162	6	acute	acute	JJ
cord-257662-viy65y72	162	7	encephalitis	encephalitis	RB
cord-257662-viy65y72	162	8	,	,	,
cord-257662-viy65y72	162	9	followed	follow	VBN
cord-257662-viy65y72	162	10	by	by	IN
cord-257662-viy65y72	162	11	a	a	DT
cord-257662-viy65y72	162	12	non	non	JJ
cord-257662-viy65y72	162	13	-	-	JJ
cord-257662-viy65y72	162	14	lethal	lethal	JJ
cord-257662-viy65y72	162	15	,	,	,
cord-257662-viy65y72	162	16	chronic	chronic	JJ
cord-257662-viy65y72	162	17	demyelinating	demyelinating	NN
cord-257662-viy65y72	162	18	disease	disease	NN
cord-257662-viy65y72	162	19	(	(	-LRB-
cord-257662-viy65y72	162	20	68	68	CD
cord-257662-viy65y72	162	21	)	)	-RRB-
cord-257662-viy65y72	162	22	.	.	.
cord-257662-viy65y72	163	1	In	in	IN
cord-257662-viy65y72	163	2	marked	marked	JJ
cord-257662-viy65y72	163	3	contrast	contrast	NN
cord-257662-viy65y72	163	4	,	,	,
cord-257662-viy65y72	163	5	rJ2.2	rj2.2	CD
cord-257662-viy65y72	163	6	infection	infection	NN
cord-257662-viy65y72	163	7	of	of	IN
cord-257662-viy65y72	163	8	mice	mouse	NNS
cord-257662-viy65y72	163	9	that	that	WDT
cord-257662-viy65y72	163	10	transgenically	transgenically	RB
cord-257662-viy65y72	163	11	express	express	VBP
cord-257662-viy65y72	163	12	CCL2	CCL2	NNP
cord-257662-viy65y72	163	13	in	in	IN
cord-257662-viy65y72	163	14	the	the	DT
cord-257662-viy65y72	163	15	brain	brain	NN
cord-257662-viy65y72	163	16	(	(	-LRB-
cord-257662-viy65y72	163	17	CCL2	CCL2	NNP
cord-257662-viy65y72	163	18	Tg	Tg	NNP
cord-257662-viy65y72	163	19	)	)	-RRB-
cord-257662-viy65y72	163	20	ineffectively	ineffectively	RB
cord-257662-viy65y72	163	21	cleared	clear	VBD
cord-257662-viy65y72	163	22	virus	virus	NN
cord-257662-viy65y72	163	23	and	and	CC
cord-257662-viy65y72	163	24	rapidly	rapidly	RB
cord-257662-viy65y72	163	25	succumbed	succumb	VBD
cord-257662-viy65y72	163	26	to	to	IN
cord-257662-viy65y72	163	27	the	the	DT
cord-257662-viy65y72	163	28	infection	infection	NN
cord-257662-viy65y72	163	29	(	(	-LRB-
cord-257662-viy65y72	163	30	68	68	CD
cord-257662-viy65y72	163	31	)	)	-RRB-
cord-257662-viy65y72	163	32	.	.	.
cord-257662-viy65y72	164	1	CCL2	CCL2	NNP
cord-257662-viy65y72	164	2	Tg	Tg	NNP
cord-257662-viy65y72	164	3	mice	mouse	NNS
cord-257662-viy65y72	164	4	mounted	mount	VBD
cord-257662-viy65y72	164	5	a	a	DT
cord-257662-viy65y72	164	6	dysregulated	dysregulate	VBN
cord-257662-viy65y72	164	7	immune	immune	JJ
cord-257662-viy65y72	164	8	response	response	NN
cord-257662-viy65y72	164	9	,	,	,
cord-257662-viy65y72	164	10	characterized	characterize	VBN
cord-257662-viy65y72	164	11	by	by	IN
cord-257662-viy65y72	164	12	increased	increase	VBN
cord-257662-viy65y72	164	13	accumulation	accumulation	NN
cord-257662-viy65y72	164	14	of	of	IN
cord-257662-viy65y72	164	15	iNOS	inos	NN
cord-257662-viy65y72	164	16	-	-	HYPH
cord-257662-viy65y72	164	17	expressing	express	VBG
cord-257662-viy65y72	164	18	macrophages	macrophage	NNS
cord-257662-viy65y72	164	19	and	and	CC
cord-257662-viy65y72	164	20	microglia	microglia	NN
cord-257662-viy65y72	164	21	as	as	RB
cord-257662-viy65y72	164	22	well	well	RB
cord-257662-viy65y72	164	23	as	as	IN
cord-257662-viy65y72	164	24	regulatory	regulatory	JJ
cord-257662-viy65y72	164	25	T	t	NN
cord-257662-viy65y72	164	26	cells	cell	NNS
cord-257662-viy65y72	164	27	,	,	,
cord-257662-viy65y72	164	28	but	but	CC
cord-257662-viy65y72	164	29	decreased	decrease	VBD
cord-257662-viy65y72	164	30	Arg1	arg1	JJ
cord-257662-viy65y72	164	31	expression	expression	NN
cord-257662-viy65y72	164	32	(	(	-LRB-
cord-257662-viy65y72	164	33	68	68	CD
cord-257662-viy65y72	164	34	)	)	-RRB-
cord-257662-viy65y72	164	35	.	.	.
cord-257662-viy65y72	165	1	These	these	DT
cord-257662-viy65y72	165	2	data	datum	NNS
cord-257662-viy65y72	165	3	suggest	suggest	VBP
cord-257662-viy65y72	165	4	that	that	IN
cord-257662-viy65y72	165	5	persistent	persistent	JJ
cord-257662-viy65y72	165	6	CCL2	CCL2	NNP
cord-257662-viy65y72	165	7	overexpression	overexpression	NN
cord-257662-viy65y72	165	8	establishes	establish	VBZ
cord-257662-viy65y72	165	9	and	and	CC
cord-257662-viy65y72	165	10	sustains	sustain	VBZ
cord-257662-viy65y72	165	11	an	an	DT
cord-257662-viy65y72	165	12	immunological	immunological	JJ
cord-257662-viy65y72	165	13	milieu	milieu	NN
cord-257662-viy65y72	165	14	that	that	WDT
cord-257662-viy65y72	165	15	may	may	MD
cord-257662-viy65y72	165	16	predispose	predispose	VB
cord-257662-viy65y72	165	17	mice	mouse	NNS
cord-257662-viy65y72	165	18	to	to	IN
cord-257662-viy65y72	165	19	a	a	DT
cord-257662-viy65y72	165	20	defective	defective	JJ
cord-257662-viy65y72	165	21	immune	immune	JJ
cord-257662-viy65y72	165	22	response	response	NN
cord-257662-viy65y72	165	23	to	to	IN
cord-257662-viy65y72	165	24	a	a	DT
cord-257662-viy65y72	165	25	typically	typically	RB
cord-257662-viy65y72	165	26	minimally	minimally	RB
cord-257662-viy65y72	165	27	virulent	virulent	JJ
cord-257662-viy65y72	165	28	virus	virus	NN
cord-257662-viy65y72	165	29	.	.	.
cord-257662-viy65y72	166	1	Arginase	arginase	NN
cord-257662-viy65y72	166	2	activity	activity	NN
cord-257662-viy65y72	166	3	is	be	VBZ
cord-257662-viy65y72	166	4	important	important	JJ
cord-257662-viy65y72	166	5	for	for	IN
cord-257662-viy65y72	166	6	wound	wound	JJ
cord-257662-viy65y72	166	7	healing	healing	NN
cord-257662-viy65y72	166	8	and	and	CC
cord-257662-viy65y72	166	9	tissue	tissue	NN
cord-257662-viy65y72	166	10	regeneration	regeneration	NN
cord-257662-viy65y72	166	11	through	through	IN
cord-257662-viy65y72	166	12	the	the	DT
cord-257662-viy65y72	166	13	production	production	NN
cord-257662-viy65y72	166	14	of	of	IN
cord-257662-viy65y72	166	15	polyamines	polyamine	NNS
cord-257662-viy65y72	166	16	and	and	CC
cord-257662-viy65y72	166	17	proline	proline	NN
cord-257662-viy65y72	166	18	(	(	-LRB-
cord-257662-viy65y72	166	19	2	2	CD
cord-257662-viy65y72	166	20	)	)	-RRB-
cord-257662-viy65y72	166	21	.	.	.
cord-257662-viy65y72	167	1	In	in	IN
cord-257662-viy65y72	167	2	the	the	DT
cord-257662-viy65y72	167	3	context	context	NN
cord-257662-viy65y72	167	4	of	of	IN
cord-257662-viy65y72	167	5	some	some	DT
cord-257662-viy65y72	167	6	viral	viral	JJ
cord-257662-viy65y72	167	7	infections	infection	NNS
cord-257662-viy65y72	167	8	,	,	,
cord-257662-viy65y72	167	9	arginase	arginase	NN
cord-257662-viy65y72	167	10	activity	activity	NN
cord-257662-viy65y72	167	11	and	and	CC
cord-257662-viy65y72	167	12	M2	M2	NNP
cord-257662-viy65y72	167	13	macrophage	macrophage	NN
cord-257662-viy65y72	167	14	activation	activation	NN
cord-257662-viy65y72	167	15	have	have	VBP
cord-257662-viy65y72	167	16	been	be	VBN
cord-257662-viy65y72	167	17	shown	show	VBN
cord-257662-viy65y72	167	18	to	to	TO
cord-257662-viy65y72	167	19	be	be	VB
cord-257662-viy65y72	167	20	beneficial	beneficial	JJ
cord-257662-viy65y72	167	21	for	for	IN
cord-257662-viy65y72	167	22	tissue	tissue	NN
cord-257662-viy65y72	167	23	repair	repair	NN
cord-257662-viy65y72	167	24	following	follow	VBG
cord-257662-viy65y72	167	25	virus	virus	NN
cord-257662-viy65y72	167	26	-	-	HYPH
cord-257662-viy65y72	167	27	induced	induce	VBN
cord-257662-viy65y72	167	28	damage	damage	NN
cord-257662-viy65y72	167	29	.	.	.
cord-257662-viy65y72	168	1	For	for	IN
cord-257662-viy65y72	168	2	instance	instance	NN
cord-257662-viy65y72	168	3	,	,	,
cord-257662-viy65y72	168	4	resolution	resolution	NN
cord-257662-viy65y72	168	5	of	of	IN
cord-257662-viy65y72	168	6	severe	severe	JJ
cord-257662-viy65y72	168	7	respiratory	respiratory	JJ
cord-257662-viy65y72	168	8	syncytial	syncytial	JJ
cord-257662-viy65y72	168	9	virus	virus	NN
cord-257662-viy65y72	168	10	(	(	-LRB-
cord-257662-viy65y72	168	11	RSV)-induced	rsv)-induce	VBN
cord-257662-viy65y72	168	12	bronchiolitis	bronchiolitis	NN
cord-257662-viy65y72	168	13	in	in	IN
cord-257662-viy65y72	168	14	mice	mouse	NNS
cord-257662-viy65y72	168	15	is	be	VBZ
cord-257662-viy65y72	168	16	mediated	mediate	VBN
cord-257662-viy65y72	168	17	by	by	IN
cord-257662-viy65y72	168	18	M2	M2	NNP
cord-257662-viy65y72	168	19	macrophages	macrophage	NNS
cord-257662-viy65y72	168	20	that	that	WDT
cord-257662-viy65y72	168	21	counteract	counteract	VBP
cord-257662-viy65y72	168	22	cyclooxygenase	cyclooxygenase	JJ
cord-257662-viy65y72	168	23	(	(	-LRB-
cord-257662-viy65y72	168	24	COX)-2-induced	cox)-2-induced	JJ
cord-257662-viy65y72	168	25	lung	lung	NN
cord-257662-viy65y72	168	26	pathology	pathology	NN
cord-257662-viy65y72	168	27	(	(	-LRB-
cord-257662-viy65y72	168	28	19	19	CD
cord-257662-viy65y72	168	29	,	,	,
cord-257662-viy65y72	168	30	20	20	CD
cord-257662-viy65y72	168	31	)	)	-RRB-
cord-257662-viy65y72	168	32	.	.	.
cord-257662-viy65y72	169	1	Arg1	Arg1	NNP
cord-257662-viy65y72	169	2	was	be	VBD
cord-257662-viy65y72	169	3	induced	induce	VBN
cord-257662-viy65y72	169	4	in	in	IN
cord-257662-viy65y72	169	5	the	the	DT
cord-257662-viy65y72	169	6	lungs	lung	NNS
cord-257662-viy65y72	169	7	of	of	IN
cord-257662-viy65y72	169	8	RSV	RSV	NNP
cord-257662-viy65y72	169	9	-	-	HYPH
cord-257662-viy65y72	169	10	infected	infect	VBN
cord-257662-viy65y72	169	11	mice	mouse	NNS
cord-257662-viy65y72	169	12	,	,	,
cord-257662-viy65y72	169	13	and	and	CC
cord-257662-viy65y72	169	14	its	-PRON-	PRP$
cord-257662-viy65y72	169	15	induction	induction	NN
cord-257662-viy65y72	169	16	was	be	VBD
cord-257662-viy65y72	169	17	shown	show	VBN
cord-257662-viy65y72	169	18	to	to	TO
cord-257662-viy65y72	169	19	be	be	VB
cord-257662-viy65y72	169	20	IL-4Rα	il-4rα	RB
cord-257662-viy65y72	169	21	-	-	HYPH
cord-257662-viy65y72	169	22	dependent	dependent	JJ
cord-257662-viy65y72	169	23	(	(	-LRB-
cord-257662-viy65y72	169	24	19	19	CD
cord-257662-viy65y72	169	25	)	)	-RRB-
cord-257662-viy65y72	169	26	.	.	.
cord-257662-viy65y72	170	1	Additionally	additionally	RB
cord-257662-viy65y72	170	2	,	,	,
cord-257662-viy65y72	170	3	WT	WT	NNP
cord-257662-viy65y72	170	4	macrophages	macrophage	NNS
cord-257662-viy65y72	170	5	adoptively	adoptively	RB
cord-257662-viy65y72	170	6	transferred	transfer	VBN
cord-257662-viy65y72	170	7	into	into	IN
cord-257662-viy65y72	170	8	RSV	RSV	NNP
cord-257662-viy65y72	170	9	-	-	HYPH
cord-257662-viy65y72	170	10	infected	infect	VBN
cord-257662-viy65y72	170	11	IL-4Rα	IL-4Rα	NNP
cord-257662-viy65y72	170	12	−/−	−/−	NNP
cord-257662-viy65y72	170	13	mice	mouse	NNS
cord-257662-viy65y72	170	14	restored	restore	VBD
cord-257662-viy65y72	170	15	the	the	DT
cord-257662-viy65y72	170	16	www.frontiersin.org	www.frontiersin.org	IN
cord-257662-viy65y72	170	17	M2	m2	JJ
cord-257662-viy65y72	170	18	phenotype	phenotype	NN
cord-257662-viy65y72	170	19	in	in	IN
cord-257662-viy65y72	170	20	the	the	DT
cord-257662-viy65y72	170	21	lungs	lung	NNS
cord-257662-viy65y72	170	22	and	and	CC
cord-257662-viy65y72	170	23	decreased	decrease	VBD
cord-257662-viy65y72	170	24	lung	lung	NN
cord-257662-viy65y72	170	25	pathology	pathology	NN
cord-257662-viy65y72	170	26	(	(	-LRB-
cord-257662-viy65y72	170	27	19	19	CD
cord-257662-viy65y72	170	28	)	)	-RRB-
cord-257662-viy65y72	170	29	.	.	.
cord-257662-viy65y72	171	1	It	-PRON-	PRP
cord-257662-viy65y72	171	2	was	be	VBD
cord-257662-viy65y72	171	3	further	further	RB
cord-257662-viy65y72	171	4	shown	show	VBN
cord-257662-viy65y72	171	5	that	that	IN
cord-257662-viy65y72	171	6	the	the	DT
cord-257662-viy65y72	171	7	lipoxogenase	lipoxogenase	NNP
cord-257662-viy65y72	171	8	pathway	pathway	NN
cord-257662-viy65y72	171	9	was	be	VBD
cord-257662-viy65y72	171	10	important	important	JJ
cord-257662-viy65y72	171	11	for	for	IN
cord-257662-viy65y72	171	12	M2	M2	NNP
cord-257662-viy65y72	171	13	macrophage	macrophage	NN
cord-257662-viy65y72	171	14	activation	activation	NN
cord-257662-viy65y72	171	15	and	and	CC
cord-257662-viy65y72	171	16	lung	lung	NN
cord-257662-viy65y72	171	17	resolution	resolution	NN
cord-257662-viy65y72	171	18	following	follow	VBG
cord-257662-viy65y72	171	19	RSV	RSV	NNP
cord-257662-viy65y72	171	20	infection	infection	NN
cord-257662-viy65y72	171	21	(	(	-LRB-
cord-257662-viy65y72	171	22	20	20	CD
cord-257662-viy65y72	171	23	)	)	-RRB-
cord-257662-viy65y72	171	24	.	.	.
cord-257662-viy65y72	172	1	Most	most	RBS
cord-257662-viy65y72	172	2	recently	recently	RB
cord-257662-viy65y72	172	3	it	-PRON-	PRP
cord-257662-viy65y72	172	4	was	be	VBD
cord-257662-viy65y72	172	5	demonstrated	demonstrate	VBN
cord-257662-viy65y72	172	6	that	that	IN
cord-257662-viy65y72	172	7	treating	treat	VBG
cord-257662-viy65y72	172	8	mice	mouse	NNS
cord-257662-viy65y72	172	9	with	with	IN
cord-257662-viy65y72	172	10	agents	agent	NNS
cord-257662-viy65y72	172	11	that	that	WDT
cord-257662-viy65y72	172	12	sustain	sustain	VBP
cord-257662-viy65y72	172	13	Arg1	arg1	JJ
cord-257662-viy65y72	172	14	expression	expression	NN
cord-257662-viy65y72	172	15	(	(	-LRB-
cord-257662-viy65y72	172	16	e.g.	e.g.	RB
cord-257662-viy65y72	172	17	,	,	,
cord-257662-viy65y72	172	18	IL-4	IL-4	NNP
cord-257662-viy65y72	172	19	/	/	SYM
cord-257662-viy65y72	172	20	anti	anti	JJ
cord-257662-viy65y72	172	21	-	-	JJ
cord-257662-viy65y72	172	22	IL-4	il-4	JJ
cord-257662-viy65y72	172	23	immune	immune	JJ
cord-257662-viy65y72	172	24	complexes	complex	NNS
cord-257662-viy65y72	172	25	)	)	-RRB-
cord-257662-viy65y72	173	1	limited	limited	JJ
cord-257662-viy65y72	173	2	RSV	RSV	NNP
cord-257662-viy65y72	173	3	-	-	HYPH
cord-257662-viy65y72	173	4	induced	induce	VBN
cord-257662-viy65y72	173	5	lung	lung	NN
cord-257662-viy65y72	173	6	pathology	pathology	NN
cord-257662-viy65y72	173	7	(	(	-LRB-
cord-257662-viy65y72	173	8	21	21	CD
cord-257662-viy65y72	173	9	)	)	-RRB-
cord-257662-viy65y72	173	10	.	.	.
cord-257662-viy65y72	174	1	Consistent	consistent	JJ
cord-257662-viy65y72	174	2	with	with	IN
cord-257662-viy65y72	174	3	a	a	DT
cord-257662-viy65y72	174	4	pathogenic	pathogenic	JJ
cord-257662-viy65y72	174	5	role	role	NN
cord-257662-viy65y72	174	6	for	for	IN
cord-257662-viy65y72	174	7	iNOS/	inos/	NN
cord-257662-viy65y72	175	1	NO	no	DT
cord-257662-viy65y72	175	2	following	follow	VBG
cord-257662-viy65y72	175	3	influenza	influenza	NN
cord-257662-viy65y72	175	4	infection	infection	NN
cord-257662-viy65y72	175	5	(	(	-LRB-
cord-257662-viy65y72	175	6	described	describe	VBN
cord-257662-viy65y72	175	7	above	above	IN
cord-257662-viy65y72	175	8	)	)	-RRB-
cord-257662-viy65y72	175	9	,	,	,
cord-257662-viy65y72	175	10	it	-PRON-	PRP
cord-257662-viy65y72	175	11	was	be	VBD
cord-257662-viy65y72	175	12	recently	recently	RB
cord-257662-viy65y72	175	13	shown	show	VBN
cord-257662-viy65y72	175	14	that	that	IN
cord-257662-viy65y72	175	15	the	the	DT
cord-257662-viy65y72	175	16	presence	presence	NN
cord-257662-viy65y72	175	17	of	of	IN
cord-257662-viy65y72	175	18	airway	airway	NN
cord-257662-viy65y72	175	19	bacteria	bacteria	NNS
cord-257662-viy65y72	175	20	polarize	polarize	VBP
cord-257662-viy65y72	175	21	alveolar	alveolar	JJ
cord-257662-viy65y72	175	22	macrophages	macrophage	NNS
cord-257662-viy65y72	175	23	into	into	IN
cord-257662-viy65y72	175	24	a	a	DT
cord-257662-viy65y72	175	25	M2	m2	JJ
cord-257662-viy65y72	175	26	phenotype	phenotype	NN
cord-257662-viy65y72	175	27	,	,	,
cord-257662-viy65y72	175	28	thus	thus	RB
cord-257662-viy65y72	175	29	limiting	limit	VBG
cord-257662-viy65y72	175	30	influenza	influenza	NN
cord-257662-viy65y72	175	31	-	-	HYPH
cord-257662-viy65y72	175	32	mediated	mediate	VBN
cord-257662-viy65y72	175	33	lethal	lethal	JJ
cord-257662-viy65y72	175	34	lung	lung	NN
cord-257662-viy65y72	175	35	inflammation	inflammation	NN
cord-257662-viy65y72	175	36	.	.	.
cord-257662-viy65y72	176	1	Wang	Wang	NNP
cord-257662-viy65y72	176	2	and	and	CC
cord-257662-viy65y72	176	3	colleagues	colleague	NNS
cord-257662-viy65y72	176	4	(	(	-LRB-
cord-257662-viy65y72	176	5	27	27	CD
cord-257662-viy65y72	176	6	)	)	-RRB-
cord-257662-viy65y72	176	7	demonstrated	demonstrate	VBD
cord-257662-viy65y72	176	8	that	that	IN
cord-257662-viy65y72	176	9	priming	prime	VBG
cord-257662-viy65y72	176	10	with	with	IN
cord-257662-viy65y72	176	11	Staphylococcus	Staphylococcus	NNP
cord-257662-viy65y72	176	12	aureus	aureus	NN
cord-257662-viy65y72	176	13	,	,	,
cord-257662-viy65y72	176	14	which	which	WDT
cord-257662-viy65y72	176	15	commonly	commonly	RB
cord-257662-viy65y72	176	16	colonizes	colonize	VBZ
cord-257662-viy65y72	176	17	the	the	DT
cord-257662-viy65y72	176	18	upper	upper	JJ
cord-257662-viy65y72	176	19	respiratory	respiratory	JJ
cord-257662-viy65y72	176	20	mucosa	mucosa	NN
cord-257662-viy65y72	176	21	,	,	,
cord-257662-viy65y72	176	22	attenuated	attenuated	JJ
cord-257662-viy65y72	176	23	influenzamediated	influenzamediated	JJ
cord-257662-viy65y72	176	24	lung	lung	NN
cord-257662-viy65y72	176	25	injury	injury	NN
cord-257662-viy65y72	176	26	via	via	IN
cord-257662-viy65y72	176	27	TLR2	TLR2	NNP
cord-257662-viy65y72	176	28	signaling	signaling	NN
cord-257662-viy65y72	176	29	that	that	WDT
cord-257662-viy65y72	176	30	recruited	recruit	VBD
cord-257662-viy65y72	176	31	peripheral	peripheral	JJ
cord-257662-viy65y72	176	32	CCR2	CCR2	NNP
cord-257662-viy65y72	176	33	+	+	SYM
cord-257662-viy65y72	176	34	CD11b	CD11b	NNS
cord-257662-viy65y72	176	35	+	+	SYM
cord-257662-viy65y72	176	36	monocytes	monocyte	NNS
cord-257662-viy65y72	176	37	into	into	IN
cord-257662-viy65y72	176	38	the	the	DT
cord-257662-viy65y72	176	39	alveoli	alveolus	NNS
cord-257662-viy65y72	176	40	(	(	-LRB-
cord-257662-viy65y72	176	41	27	27	CD
cord-257662-viy65y72	176	42	)	)	-RRB-
cord-257662-viy65y72	176	43	.	.	.
cord-257662-viy65y72	177	1	These	these	DT
cord-257662-viy65y72	177	2	monocytes	monocyte	NNS
cord-257662-viy65y72	177	3	polarized	polarize	VBD
cord-257662-viy65y72	177	4	alveolar	alveolar	NN
cord-257662-viy65y72	177	5	macrophages	macrophage	NNS
cord-257662-viy65y72	177	6	into	into	IN
cord-257662-viy65y72	177	7	a	a	DT
cord-257662-viy65y72	177	8	M2	m2	JJ
cord-257662-viy65y72	177	9	phenotype	phenotype	NN
cord-257662-viy65y72	177	10	characterized	characterize	VBN
cord-257662-viy65y72	177	11	by	by	IN
cord-257662-viy65y72	177	12	high	high	JJ
cord-257662-viy65y72	177	13	Arg1	Arg1	NNP
cord-257662-viy65y72	177	14	as	as	RB
cord-257662-viy65y72	177	15	well	well	RB
cord-257662-viy65y72	177	16	as	as	IN
cord-257662-viy65y72	177	17	Ym1	ym1	CD
cord-257662-viy65y72	177	18	,	,	,
cord-257662-viy65y72	177	19	FIZZ1	FIZZ1	NNP
cord-257662-viy65y72	177	20	,	,	,
cord-257662-viy65y72	177	21	and	and	CC
cord-257662-viy65y72	177	22	IL-10	IL-10	NNP
cord-257662-viy65y72	177	23	expression	expression	NN
cord-257662-viy65y72	177	24	(	(	-LRB-
cord-257662-viy65y72	177	25	27	27	CD
cord-257662-viy65y72	177	26	)	)	-RRB-
cord-257662-viy65y72	177	27	.	.	.
cord-257662-viy65y72	178	1	It	-PRON-	PRP
cord-257662-viy65y72	178	2	was	be	VBD
cord-257662-viy65y72	178	3	further	further	RB
cord-257662-viy65y72	178	4	shown	show	VBN
cord-257662-viy65y72	178	5	that	that	IN
cord-257662-viy65y72	178	6	S.	S.	NNP
cord-257662-viy65y72	178	7	aureus	aureus	NN
cord-257662-viy65y72	178	8	-	-	HYPH
cord-257662-viy65y72	178	9	primed	prime	VBN
cord-257662-viy65y72	178	10	M2	M2	NNP
cord-257662-viy65y72	178	11	alveolar	alveolar	NN
cord-257662-viy65y72	178	12	macrophages	macrophage	NNS
cord-257662-viy65y72	178	13	inhibited	inhibit	VBD
cord-257662-viy65y72	178	14	inflammatory	inflammatory	JJ
cord-257662-viy65y72	178	15	cell	cell	NN
cord-257662-viy65y72	178	16	recruitment	recruitment	NN
cord-257662-viy65y72	178	17	to	to	IN
cord-257662-viy65y72	178	18	the	the	DT
cord-257662-viy65y72	178	19	lung	lung	NN
cord-257662-viy65y72	178	20	,	,	,
cord-257662-viy65y72	178	21	including	include	VBG
cord-257662-viy65y72	178	22	neutrophils	neutrophil	NNS
cord-257662-viy65y72	178	23	,	,	,
cord-257662-viy65y72	178	24	NK	NK	NNP
cord-257662-viy65y72	178	25	cells	cell	NNS
cord-257662-viy65y72	178	26	,	,	,
cord-257662-viy65y72	178	27	and	and	CC
cord-257662-viy65y72	178	28	CD8	CD8	NNP
cord-257662-viy65y72	178	29	T	T	NNP
cord-257662-viy65y72	178	30	cells	cell	NNS
cord-257662-viy65y72	178	31	(	(	-LRB-
cord-257662-viy65y72	178	32	27	27	CD
cord-257662-viy65y72	178	33	)	)	-RRB-
cord-257662-viy65y72	178	34	.	.	.
cord-257662-viy65y72	179	1	S.	S.	NNP
cord-257662-viy65y72	179	2	aureus	aureus	NN
cord-257662-viy65y72	179	3	-	-	HYPH
cord-257662-viy65y72	179	4	primed	prime	VBN
cord-257662-viy65y72	179	5	M2	M2	NNP
cord-257662-viy65y72	179	6	alveolar	alveolar	NN
cord-257662-viy65y72	179	7	macrophages	macrophage	NNS
cord-257662-viy65y72	179	8	also	also	RB
cord-257662-viy65y72	179	9	expressed	express	VBD
cord-257662-viy65y72	179	10	higher	high	JJR
cord-257662-viy65y72	179	11	levels	level	NNS
cord-257662-viy65y72	179	12	of	of	IN
cord-257662-viy65y72	179	13	the	the	DT
cord-257662-viy65y72	179	14	inhibitory	inhibitory	JJ
cord-257662-viy65y72	179	15	ligand	ligand	NN
cord-257662-viy65y72	179	16	PD	PD	NNP
cord-257662-viy65y72	179	17	-	-	HYPH
cord-257662-viy65y72	179	18	L1	L1	NNP
cord-257662-viy65y72	179	19	(	(	-LRB-
cord-257662-viy65y72	179	20	27	27	CD
cord-257662-viy65y72	179	21	)	)	-RRB-
cord-257662-viy65y72	179	22	,	,	,
cord-257662-viy65y72	179	23	suggesting	suggest	VBG
cord-257662-viy65y72	179	24	that	that	IN
cord-257662-viy65y72	179	25	expression	expression	NN
cord-257662-viy65y72	179	26	of	of	IN
cord-257662-viy65y72	179	27	a	a	DT
cord-257662-viy65y72	179	28	combination	combination	NN
cord-257662-viy65y72	179	29	of	of	IN
cord-257662-viy65y72	179	30	anti	anti	JJ
cord-257662-viy65y72	179	31	-	-	JJ
cord-257662-viy65y72	179	32	inflammatory	inflammatory	JJ
cord-257662-viy65y72	179	33	cytokines	cytokine	NNS
cord-257662-viy65y72	179	34	and	and	CC
cord-257662-viy65y72	179	35	inhibitory	inhibitory	JJ
cord-257662-viy65y72	179	36	ligands	ligand	NNS
cord-257662-viy65y72	179	37	could	could	MD
cord-257662-viy65y72	179	38	be	be	VB
cord-257662-viy65y72	179	39	the	the	DT
cord-257662-viy65y72	179	40	mechanisms	mechanism	NNS
cord-257662-viy65y72	179	41	by	by	IN
cord-257662-viy65y72	179	42	which	which	WDT
cord-257662-viy65y72	179	43	S.	S.	NNP
cord-257662-viy65y72	179	44	aureusprimed	aureusprime	VBD
cord-257662-viy65y72	179	45	M2	M2	NNP
cord-257662-viy65y72	179	46	alveolar	alveolar	NN
cord-257662-viy65y72	179	47	macrophages	macrophage	NNS
cord-257662-viy65y72	179	48	limit	limit	VBP
cord-257662-viy65y72	179	49	influenza	influenza	NN
cord-257662-viy65y72	179	50	-	-	HYPH
cord-257662-viy65y72	179	51	mediated	mediate	VBN
cord-257662-viy65y72	179	52	lung	lung	NN
cord-257662-viy65y72	179	53	inflammation	inflammation	NN
cord-257662-viy65y72	179	54	.	.	.
cord-257662-viy65y72	180	1	As	as	IN
cord-257662-viy65y72	180	2	discussed	discuss	VBN
cord-257662-viy65y72	180	3	above	above	RB
cord-257662-viy65y72	180	4	,	,	,
cord-257662-viy65y72	180	5	coxsackievirus	coxsackievirus	NNP
cord-257662-viy65y72	180	6	B3	B3	NNP
cord-257662-viy65y72	180	7	(	(	-LRB-
cord-257662-viy65y72	180	8	CVB3	CVB3	NNP
cord-257662-viy65y72	180	9	)	)	-RRB-
cord-257662-viy65y72	180	10	infection	infection	NN
cord-257662-viy65y72	180	11	causes	cause	VBZ
cord-257662-viy65y72	180	12	myocarditis	myocarditis	NN
cord-257662-viy65y72	180	13	in	in	IN
cord-257662-viy65y72	180	14	human	human	JJ
cord-257662-viy65y72	180	15	beings	being	NNS
cord-257662-viy65y72	180	16	as	as	RB
cord-257662-viy65y72	180	17	well	well	RB
cord-257662-viy65y72	180	18	as	as	IN
cord-257662-viy65y72	180	19	in	in	IN
cord-257662-viy65y72	180	20	male	male	JJ
cord-257662-viy65y72	180	21	BALB	BALB	NNP
cord-257662-viy65y72	180	22	/	/	SYM
cord-257662-viy65y72	180	23	c	c	NN
cord-257662-viy65y72	180	24	mice	mouse	NNS
cord-257662-viy65y72	180	25	.	.	.
cord-257662-viy65y72	181	1	Although	although	IN
cord-257662-viy65y72	181	2	female	female	JJ
cord-257662-viy65y72	181	3	mice	mouse	NNS
cord-257662-viy65y72	181	4	do	do	VBP
cord-257662-viy65y72	181	5	not	not	RB
cord-257662-viy65y72	181	6	develop	develop	VB
cord-257662-viy65y72	181	7	severe	severe	JJ
cord-257662-viy65y72	181	8	myocarditis	myocarditis	NN
cord-257662-viy65y72	181	9	,	,	,
cord-257662-viy65y72	181	10	both	both	CC
cord-257662-viy65y72	181	11	male	male	JJ
cord-257662-viy65y72	181	12	and	and	CC
cord-257662-viy65y72	181	13	female	female	JJ
cord-257662-viy65y72	181	14	mice	mouse	NNS
cord-257662-viy65y72	181	15	have	have	VBP
cord-257662-viy65y72	181	16	comparable	comparable	JJ
cord-257662-viy65y72	181	17	numbers	number	NNS
cord-257662-viy65y72	181	18	of	of	IN
cord-257662-viy65y72	181	19	infiltrating	infiltrate	VBG
cord-257662-viy65y72	181	20	macrophages	macrophage	NNS
cord-257662-viy65y72	181	21	and	and	CC
cord-257662-viy65y72	181	22	viral	viral	JJ
cord-257662-viy65y72	181	23	titers	titer	NNS
cord-257662-viy65y72	181	24	in	in	IN
cord-257662-viy65y72	181	25	the	the	DT
cord-257662-viy65y72	181	26	heart	heart	NN
cord-257662-viy65y72	181	27	following	follow	VBG
cord-257662-viy65y72	181	28	CVB3	cvb3	JJ
cord-257662-viy65y72	181	29	infection	infection	NN
cord-257662-viy65y72	181	30	(	(	-LRB-
cord-257662-viy65y72	181	31	30	30	CD
cord-257662-viy65y72	181	32	)	)	-RRB-
cord-257662-viy65y72	181	33	.	.	.
cord-257662-viy65y72	182	1	The	the	DT
cord-257662-viy65y72	182	2	macrophages	macrophage	NNS
cord-257662-viy65y72	182	3	infiltrating	infiltrate	VBG
cord-257662-viy65y72	182	4	the	the	DT
cord-257662-viy65y72	182	5	heart	heart	NN
cord-257662-viy65y72	182	6	in	in	IN
cord-257662-viy65y72	182	7	male	male	JJ
cord-257662-viy65y72	182	8	mice	mouse	NNS
cord-257662-viy65y72	182	9	were	be	VBD
cord-257662-viy65y72	182	10	skewed	skewed	JJ
cord-257662-viy65y72	182	11	toward	toward	IN
cord-257662-viy65y72	182	12	a	a	DT
cord-257662-viy65y72	182	13	M1	M1	NNP
cord-257662-viy65y72	182	14	phenotype	phenotype	NN
cord-257662-viy65y72	182	15	characterized	characterize	VBN
cord-257662-viy65y72	182	16	by	by	IN
cord-257662-viy65y72	182	17	high	high	JJ
cord-257662-viy65y72	182	18	expression	expression	NN
cord-257662-viy65y72	182	19	of	of	IN
cord-257662-viy65y72	182	20	iNOS	inos	NN
cord-257662-viy65y72	182	21	(	(	-LRB-
cord-257662-viy65y72	182	22	17	17	CD
cord-257662-viy65y72	182	23	)	)	-RRB-
cord-257662-viy65y72	182	24	as	as	RB
cord-257662-viy65y72	182	25	well	well	RB
cord-257662-viy65y72	182	26	as	as	IN
cord-257662-viy65y72	182	27	M1-associated	m1-associated	JJ
cord-257662-viy65y72	182	28	cytokines	cytokine	NNS
cord-257662-viy65y72	182	29	such	such	JJ
cord-257662-viy65y72	182	30	as	as	IN
cord-257662-viy65y72	182	31	IFN	IFN	NNP
cord-257662-viy65y72	182	32	-	-	HYPH
cord-257662-viy65y72	182	33	γ	γ	NNP
cord-257662-viy65y72	182	34	and	and	CC
cord-257662-viy65y72	182	35	IL-12	IL-12	NNP
cord-257662-viy65y72	182	36	(	(	-LRB-
cord-257662-viy65y72	182	37	30	30	CD
cord-257662-viy65y72	182	38	)	)	-RRB-
cord-257662-viy65y72	182	39	.	.	.
cord-257662-viy65y72	183	1	Additionally	additionally	RB
cord-257662-viy65y72	183	2	,	,	,
cord-257662-viy65y72	183	3	inhibition	inhibition	NN
cord-257662-viy65y72	183	4	of	of	IN
cord-257662-viy65y72	183	5	NOS	NOS	NNP
cord-257662-viy65y72	183	6	resulted	result	VBD
cord-257662-viy65y72	183	7	in	in	IN
cord-257662-viy65y72	183	8	increased	increase	VBN
cord-257662-viy65y72	183	9	viral	viral	JJ
cord-257662-viy65y72	183	10	titers	titer	NNS
cord-257662-viy65y72	183	11	and	and	CC
cord-257662-viy65y72	183	12	higher	high	JJR
cord-257662-viy65y72	183	13	mortality	mortality	NN
cord-257662-viy65y72	183	14	in	in	IN
cord-257662-viy65y72	183	15	CVB3-infected	cvb3-infecte	VBN
cord-257662-viy65y72	183	16	mice	mouse	NNS
cord-257662-viy65y72	183	17	(	(	-LRB-
cord-257662-viy65y72	183	18	17	17	CD
cord-257662-viy65y72	183	19	)	)	-RRB-
cord-257662-viy65y72	183	20	,	,	,
cord-257662-viy65y72	183	21	consistent	consistent	JJ
cord-257662-viy65y72	183	22	with	with	IN
cord-257662-viy65y72	183	23	an	an	DT
cord-257662-viy65y72	183	24	antiviral	antiviral	JJ
cord-257662-viy65y72	183	25	role	role	NN
cord-257662-viy65y72	183	26	for	for	IN
cord-257662-viy65y72	183	27	NO	no	DT
cord-257662-viy65y72	183	28	during	during	IN
cord-257662-viy65y72	183	29	CVB3	cvb3	JJ
cord-257662-viy65y72	183	30	infection	infection	NN
cord-257662-viy65y72	183	31	(	(	-LRB-
cord-257662-viy65y72	183	32	see	see	VB
cord-257662-viy65y72	183	33	above	above	RB
cord-257662-viy65y72	183	34	)	)	-RRB-
cord-257662-viy65y72	183	35	.	.	.
cord-257662-viy65y72	184	1	However	however	RB
cord-257662-viy65y72	184	2	,	,	,
cord-257662-viy65y72	184	3	in	in	IN
cord-257662-viy65y72	184	4	contrast	contrast	NN
cord-257662-viy65y72	184	5	to	to	IN
cord-257662-viy65y72	184	6	male	male	JJ
cord-257662-viy65y72	184	7	mice	mouse	NNS
cord-257662-viy65y72	184	8	,	,	,
cord-257662-viy65y72	184	9	the	the	DT
cord-257662-viy65y72	184	10	heart	heart	NN
cord-257662-viy65y72	184	11	-	-	HYPH
cord-257662-viy65y72	184	12	infiltrating	infiltrate	VBG
cord-257662-viy65y72	184	13	macrophages	macrophage	NNS
cord-257662-viy65y72	184	14	in	in	IN
cord-257662-viy65y72	184	15	female	female	JJ
cord-257662-viy65y72	184	16	mice	mouse	NNS
cord-257662-viy65y72	184	17	were	be	VBD
cord-257662-viy65y72	184	18	skewed	skewed	JJ
cord-257662-viy65y72	184	19	toward	toward	IN
cord-257662-viy65y72	184	20	a	a	DT
cord-257662-viy65y72	184	21	M2	M2	NNP
cord-257662-viy65y72	184	22	phenotype	phenotype	NN
cord-257662-viy65y72	184	23	characterized	characterize	VBN
cord-257662-viy65y72	184	24	by	by	IN
cord-257662-viy65y72	184	25	high	high	JJ
cord-257662-viy65y72	184	26	expression	expression	NN
cord-257662-viy65y72	184	27	of	of	IN
cord-257662-viy65y72	184	28	Arg1	Arg1	NNP
cord-257662-viy65y72	184	29	as	as	RB
cord-257662-viy65y72	184	30	well	well	RB
cord-257662-viy65y72	184	31	as	as	IN
cord-257662-viy65y72	184	32	IL-4	IL-4	NNP
cord-257662-viy65y72	184	33	and	and	CC
cord-257662-viy65y72	184	34	IL-10	IL-10	NNP
cord-257662-viy65y72	184	35	(	(	-LRB-
cord-257662-viy65y72	184	36	30	30	CD
cord-257662-viy65y72	184	37	)	)	-RRB-
cord-257662-viy65y72	184	38	.	.	.
cord-257662-viy65y72	185	1	Moreover	moreover	RB
cord-257662-viy65y72	185	2	,	,	,
cord-257662-viy65y72	185	3	adoptive	adoptive	JJ
cord-257662-viy65y72	185	4	transfer	transfer	NN
cord-257662-viy65y72	185	5	of	of	IN
cord-257662-viy65y72	185	6	ex	ex	FW
cord-257662-viy65y72	185	7	vivo	vivo	FW
cord-257662-viy65y72	185	8	-	-	HYPH
cord-257662-viy65y72	185	9	programed	program	VBN
cord-257662-viy65y72	185	10	M1	M1	NNP
cord-257662-viy65y72	185	11	macrophages	macrophage	NNS
cord-257662-viy65y72	185	12	significantly	significantly	RB
cord-257662-viy65y72	185	13	increased	increase	VBD
cord-257662-viy65y72	185	14	myocarditis	myocarditis	NN
cord-257662-viy65y72	185	15	in	in	IN
cord-257662-viy65y72	185	16	both	both	CC
cord-257662-viy65y72	185	17	male	male	JJ
cord-257662-viy65y72	185	18	and	and	CC
cord-257662-viy65y72	185	19	female	female	JJ
cord-257662-viy65y72	185	20	mice	mouse	NNS
cord-257662-viy65y72	185	21	.	.	.
cord-257662-viy65y72	186	1	Strikingly	strikingly	RB
cord-257662-viy65y72	186	2	,	,	,
cord-257662-viy65y72	186	3	transfer	transfer	NN
cord-257662-viy65y72	186	4	of	of	IN
cord-257662-viy65y72	186	5	M2-programed	m2-programe	VBN
cord-257662-viy65y72	186	6	macrophages	macrophage	NNS
cord-257662-viy65y72	186	7	into	into	IN
cord-257662-viy65y72	186	8	susceptible	susceptible	JJ
cord-257662-viy65y72	186	9	male	male	JJ
cord-257662-viy65y72	186	10	mice	mouse	NNS
cord-257662-viy65y72	186	11	alleviated	alleviate	VBD
cord-257662-viy65y72	186	12	myocardial	myocardial	JJ
cord-257662-viy65y72	186	13	inflammation	inflammation	NN
cord-257662-viy65y72	186	14	by	by	IN
cord-257662-viy65y72	186	15	modulating	modulate	VBG
cord-257662-viy65y72	186	16	the	the	DT
cord-257662-viy65y72	186	17	local	local	JJ
cord-257662-viy65y72	186	18	cytokine	cytokine	NN
cord-257662-viy65y72	186	19	profile	profile	NN
cord-257662-viy65y72	186	20	from	from	IN
cord-257662-viy65y72	186	21	a	a	DT
cord-257662-viy65y72	186	22	M1	M1	NNP
cord-257662-viy65y72	186	23	to	to	IN
cord-257662-viy65y72	186	24	M2	m2	JJ
cord-257662-viy65y72	186	25	phenotype	phenotype	NN
cord-257662-viy65y72	186	26	and	and	CC
cord-257662-viy65y72	186	27	promoting	promote	VBG
cord-257662-viy65y72	186	28	peripheral	peripheral	JJ
cord-257662-viy65y72	186	29	regulatory	regulatory	JJ
cord-257662-viy65y72	186	30	T	t	NN
cord-257662-viy65y72	186	31	cell	cell	NN
cord-257662-viy65y72	186	32	(	(	-LRB-
cord-257662-viy65y72	186	33	Treg	Treg	NNP
cord-257662-viy65y72	186	34	)	)	-RRB-
cord-257662-viy65y72	186	35	differentiation	differentiation	NN
cord-257662-viy65y72	186	36	(	(	-LRB-
cord-257662-viy65y72	186	37	30	30	CD
cord-257662-viy65y72	186	38	)	)	-RRB-
cord-257662-viy65y72	186	39	.	.	.
cord-257662-viy65y72	187	1	Using	use	VBG
cord-257662-viy65y72	187	2	different	different	JJ
cord-257662-viy65y72	187	3	variants	variant	NNS
cord-257662-viy65y72	187	4	of	of	IN
cord-257662-viy65y72	187	5	CVB3	CVB3	NNPS
cord-257662-viy65y72	187	6	,	,	,
cord-257662-viy65y72	187	7	one	one	CD
cord-257662-viy65y72	187	8	that	that	WDT
cord-257662-viy65y72	187	9	caused	cause	VBD
cord-257662-viy65y72	187	10	myocarditis	myocarditis	NN
cord-257662-viy65y72	187	11	in	in	IN
cord-257662-viy65y72	187	12	C57BL/6	C57BL/6	NNP
cord-257662-viy65y72	187	13	mice	mouse	NNS
cord-257662-viy65y72	187	14	and	and	CC
cord-257662-viy65y72	187	15	one	one	NN
cord-257662-viy65y72	187	16	that	that	WDT
cord-257662-viy65y72	187	17	did	do	VBD
cord-257662-viy65y72	187	18	not	not	RB
cord-257662-viy65y72	187	19	,	,	,
cord-257662-viy65y72	187	20	it	-PRON-	PRP
cord-257662-viy65y72	187	21	was	be	VBD
cord-257662-viy65y72	187	22	additionally	additionally	RB
cord-257662-viy65y72	187	23	shown	show	VBN
cord-257662-viy65y72	187	24	that	that	IN
cord-257662-viy65y72	187	25	the	the	DT
cord-257662-viy65y72	187	26	myocarditic	myocarditic	JJ
cord-257662-viy65y72	187	27	variant	variant	NN
cord-257662-viy65y72	187	28	induced	induce	VBD
cord-257662-viy65y72	187	29	a	a	DT
cord-257662-viy65y72	187	30	M1	M1	NNP
cord-257662-viy65y72	187	31	macrophage	macrophage	NN
cord-257662-viy65y72	187	32	phenotype	phenotype	NN
cord-257662-viy65y72	187	33	(	(	-LRB-
cord-257662-viy65y72	187	34	31	31	CD
cord-257662-viy65y72	187	35	)	)	-RRB-
cord-257662-viy65y72	187	36	.	.	.
cord-257662-viy65y72	188	1	In	in	IN
cord-257662-viy65y72	188	2	contrast	contrast	NN
cord-257662-viy65y72	188	3	,	,	,
cord-257662-viy65y72	188	4	the	the	DT
cord-257662-viy65y72	188	5	amyocarditic	amyocarditic	JJ
cord-257662-viy65y72	188	6	variant	variant	NN
cord-257662-viy65y72	188	7	induced	induce	VBD
cord-257662-viy65y72	188	8	a	a	DT
cord-257662-viy65y72	188	9	M2	m2	JJ
cord-257662-viy65y72	188	10	macrophage	macrophage	NN
cord-257662-viy65y72	188	11	phenotype	phenotype	NN
cord-257662-viy65y72	188	12	,	,	,
cord-257662-viy65y72	188	13	which	which	WDT
cord-257662-viy65y72	188	14	was	be	VBD
cord-257662-viy65y72	188	15	also	also	RB
cord-257662-viy65y72	188	16	associated	associate	VBN
cord-257662-viy65y72	188	17	with	with	IN
cord-257662-viy65y72	188	18	the	the	DT
cord-257662-viy65y72	188	19	activation	activation	NN
cord-257662-viy65y72	188	20	of	of	IN
cord-257662-viy65y72	188	21	NKT	NKT	NNP
cord-257662-viy65y72	188	22	cells	cell	NNS
cord-257662-viy65y72	188	23	that	that	WDT
cord-257662-viy65y72	188	24	promoted	promote	VBD
cord-257662-viy65y72	188	25	a	a	DT
cord-257662-viy65y72	188	26	Treg	Treg	NNP
cord-257662-viy65y72	188	27	response	response	NN
cord-257662-viy65y72	188	28	(	(	-LRB-
cord-257662-viy65y72	188	29	31	31	CD
cord-257662-viy65y72	188	30	)	)	-RRB-
cord-257662-viy65y72	188	31	.	.	.
cord-257662-viy65y72	189	1	The	the	DT
cord-257662-viy65y72	189	2	ability	ability	NN
cord-257662-viy65y72	189	3	of	of	IN
cord-257662-viy65y72	189	4	NKT	NKT	NNP
cord-257662-viy65y72	189	5	cells	cell	NNS
cord-257662-viy65y72	189	6	to	to	TO
cord-257662-viy65y72	189	7	suppress	suppress	VB
cord-257662-viy65y72	189	8	myocarditis	myocarditis	NN
cord-257662-viy65y72	189	9	was	be	VBD
cord-257662-viy65y72	189	10	shown	show	VBN
cord-257662-viy65y72	189	11	by	by	IN
cord-257662-viy65y72	189	12	adoptive	adoptive	JJ
cord-257662-viy65y72	189	13	transfer	transfer	NN
cord-257662-viy65y72	189	14	of	of	IN
cord-257662-viy65y72	189	15	purified	purify	VBN
cord-257662-viy65y72	189	16	NKT	NKT	NNP
cord-257662-viy65y72	189	17	cells	cell	NNS
cord-257662-viy65y72	189	18	into	into	IN
cord-257662-viy65y72	189	19	NKT	NKT	NNP
cord-257662-viy65y72	189	20	knockout	knockout	NN
cord-257662-viy65y72	189	21	(	(	-LRB-
cord-257662-viy65y72	189	22	Jα18	Jα18	NNP
cord-257662-viy65y72	189	23	knockout	knockout	NN
cord-257662-viy65y72	189	24	)	)	-RRB-
cord-257662-viy65y72	189	25	mice	mouse	NNS
cord-257662-viy65y72	189	26	infected	infect	VBN
cord-257662-viy65y72	189	27	with	with	IN
cord-257662-viy65y72	189	28	the	the	DT
cord-257662-viy65y72	189	29	myocarditic	myocarditic	JJ
cord-257662-viy65y72	189	30	CVB3	CVB3	NNPS
cord-257662-viy65y72	189	31	variant	variant	NN
cord-257662-viy65y72	189	32	,	,	,
cord-257662-viy65y72	189	33	which	which	WDT
cord-257662-viy65y72	189	34	inhibited	inhibit	VBD
cord-257662-viy65y72	189	35	cardiac	cardiac	JJ
cord-257662-viy65y72	189	36	inflammation	inflammation	NN
cord-257662-viy65y72	189	37	and	and	CC
cord-257662-viy65y72	189	38	increased	increase	VBD
cord-257662-viy65y72	189	39	Treg	Treg	NNP
cord-257662-viy65y72	189	40	response	response	NN
cord-257662-viy65y72	189	41	(	(	-LRB-
cord-257662-viy65y72	189	42	31	31	CD
cord-257662-viy65y72	189	43	)	)	-RRB-
cord-257662-viy65y72	189	44	.	.	.
cord-257662-viy65y72	190	1	Cardiac	cardiac	JJ
cord-257662-viy65y72	190	2	virus	virus	NN
cord-257662-viy65y72	190	3	titers	titer	NNS
cord-257662-viy65y72	190	4	were	be	VBD
cord-257662-viy65y72	190	5	equivalent	equivalent	JJ
cord-257662-viy65y72	190	6	in	in	IN
cord-257662-viy65y72	190	7	all	all	DT
cord-257662-viy65y72	190	8	mouse	mouse	NN
cord-257662-viy65y72	190	9	strains	strain	NNS
cord-257662-viy65y72	190	10	indicating	indicate	VBG
cord-257662-viy65y72	190	11	that	that	IN
cord-257662-viy65y72	190	12	NKT	NKT	NNP
cord-257662-viy65y72	190	13	cells	cell	NNS
cord-257662-viy65y72	190	14	did	do	VBD
cord-257662-viy65y72	190	15	not	not	RB
cord-257662-viy65y72	190	16	participate	participate	VB
cord-257662-viy65y72	190	17	in	in	IN
cord-257662-viy65y72	190	18	control	control	NN
cord-257662-viy65y72	190	19	of	of	IN
cord-257662-viy65y72	190	20	virus	virus	NN
cord-257662-viy65y72	190	21	infection	infection	NN
cord-257662-viy65y72	190	22	(	(	-LRB-
cord-257662-viy65y72	190	23	31	31	CD
cord-257662-viy65y72	190	24	)	)	-RRB-
cord-257662-viy65y72	190	25	.	.	.
cord-257662-viy65y72	191	1	Thus	thus	RB
cord-257662-viy65y72	191	2	,	,	,
cord-257662-viy65y72	191	3	although	although	IN
cord-257662-viy65y72	191	4	NO	no	DT
cord-257662-viy65y72	191	5	appears	appear	VBZ
cord-257662-viy65y72	191	6	to	to	TO
cord-257662-viy65y72	191	7	have	have	VB
cord-257662-viy65y72	191	8	antiviral	antiviral	JJ
cord-257662-viy65y72	191	9	properties	property	NNS
cord-257662-viy65y72	191	10	against	against	IN
cord-257662-viy65y72	191	11	CVB3	CVB3	NNPS
cord-257662-viy65y72	191	12	,	,	,
cord-257662-viy65y72	191	13	these	these	DT
cord-257662-viy65y72	191	14	data	datum	NNS
cord-257662-viy65y72	191	15	indicate	indicate	VBP
cord-257662-viy65y72	191	16	an	an	DT
cord-257662-viy65y72	191	17	important	important	JJ
cord-257662-viy65y72	191	18	role	role	NN
cord-257662-viy65y72	191	19	for	for	IN
cord-257662-viy65y72	191	20	Arg1-expressing	arg1-expresse	VBG
cord-257662-viy65y72	191	21	M2	M2	NNP
cord-257662-viy65y72	191	22	macrophages	macrophage	NNS
cord-257662-viy65y72	191	23	in	in	IN
cord-257662-viy65y72	191	24	controlling	control	VBG
cord-257662-viy65y72	191	25	CVB3-induced	cvb3-induce	VBN
cord-257662-viy65y72	191	26	myocarditis	myocarditis	NN
cord-257662-viy65y72	191	27	.	.	.
cord-257662-viy65y72	192	1	As	as	IN
cord-257662-viy65y72	192	2	a	a	DT
cord-257662-viy65y72	192	3	consequence	consequence	NN
cord-257662-viy65y72	192	4	of	of	IN
cord-257662-viy65y72	192	5	their	-PRON-	PRP$
cord-257662-viy65y72	192	6	co	co	NN
cord-257662-viy65y72	192	7	-	-	NN
cord-257662-viy65y72	192	8	evolution	evolution	NN
cord-257662-viy65y72	192	9	with	with	IN
cord-257662-viy65y72	192	10	their	-PRON-	PRP$
cord-257662-viy65y72	192	11	hosts	host	NNS
cord-257662-viy65y72	192	12	,	,	,
cord-257662-viy65y72	192	13	viruses	virus	NNS
cord-257662-viy65y72	192	14	have	have	VBP
cord-257662-viy65y72	192	15	developed	develop	VBN
cord-257662-viy65y72	192	16	numerous	numerous	JJ
cord-257662-viy65y72	192	17	strategies	strategy	NNS
cord-257662-viy65y72	192	18	to	to	TO
cord-257662-viy65y72	192	19	evade	evade	VB
cord-257662-viy65y72	192	20	the	the	DT
cord-257662-viy65y72	192	21	host	host	NN
cord-257662-viy65y72	192	22	immune	immune	JJ
cord-257662-viy65y72	192	23	system	system	NN
cord-257662-viy65y72	192	24	and	and	CC
cord-257662-viy65y72	192	25	ensure	ensure	VB
cord-257662-viy65y72	192	26	their	-PRON-	PRP$
cord-257662-viy65y72	192	27	own	own	JJ
cord-257662-viy65y72	192	28	replication	replication	NN
cord-257662-viy65y72	192	29	and	and	CC
cord-257662-viy65y72	192	30	survival	survival	NN
cord-257662-viy65y72	192	31	.	.	.
cord-257662-viy65y72	193	1	Recent	recent	JJ
cord-257662-viy65y72	193	2	studies	study	NNS
cord-257662-viy65y72	193	3	have	have	VBP
cord-257662-viy65y72	193	4	identified	identify	VBN
cord-257662-viy65y72	193	5	a	a	DT
cord-257662-viy65y72	193	6	new	new	JJ
cord-257662-viy65y72	193	7	evasion	evasion	NN
cord-257662-viy65y72	193	8	strategy	strategy	NN
cord-257662-viy65y72	193	9	for	for	IN
cord-257662-viy65y72	193	10	viruses	virus	NNS
cord-257662-viy65y72	193	11	:	:	:
cord-257662-viy65y72	193	12	exploitation	exploitation	NN
cord-257662-viy65y72	193	13	of	of	IN
cord-257662-viy65y72	193	14	the	the	DT
cord-257662-viy65y72	193	15	host	host	NN
cord-257662-viy65y72	193	16	's	's	POS
cord-257662-viy65y72	193	17	anti	anti	JJ
cord-257662-viy65y72	193	18	-	-	JJ
cord-257662-viy65y72	193	19	inflammatory	inflammatory	JJ
cord-257662-viy65y72	193	20	,	,	,
cord-257662-viy65y72	193	21	wound	wound	JJ
cord-257662-viy65y72	193	22	repair	repair	NN
cord-257662-viy65y72	193	23	response	response	NN
cord-257662-viy65y72	193	24	to	to	TO
cord-257662-viy65y72	193	25	promote	promote	VB
cord-257662-viy65y72	193	26	chronic	chronic	JJ
cord-257662-viy65y72	193	27	infection	infection	NN
cord-257662-viy65y72	193	28	.	.	.
cord-257662-viy65y72	194	1	Two	two	CD
cord-257662-viy65y72	194	2	strains	strain	NNS
cord-257662-viy65y72	194	3	of	of	IN
cord-257662-viy65y72	194	4	LCMV	LCMV	NNP
cord-257662-viy65y72	194	5	-Armstrong	-Armstrong	.
cord-257662-viy65y72	195	1	(	(	-LRB-
cord-257662-viy65y72	195	2	Arm	Arm	NNP
cord-257662-viy65y72	195	3	)	)	-RRB-
cord-257662-viy65y72	195	4	and	and	CC
cord-257662-viy65y72	195	5	clone	clone	VB
cord-257662-viy65y72	195	6	13	13	CD
cord-257662-viy65y72	196	1	(	(	-LRB-
cord-257662-viy65y72	196	2	C13)have	C13)have	NNP
cord-257662-viy65y72	196	3	been	be	VBN
cord-257662-viy65y72	196	4	studied	study	VBN
cord-257662-viy65y72	196	5	for	for	IN
cord-257662-viy65y72	196	6	decades	decade	NNS
cord-257662-viy65y72	196	7	as	as	IN
cord-257662-viy65y72	196	8	models	model	NNS
cord-257662-viy65y72	196	9	for	for	IN
cord-257662-viy65y72	196	10	acute	acute	JJ
cord-257662-viy65y72	196	11	and	and	CC
cord-257662-viy65y72	196	12	chronic	chronic	JJ
cord-257662-viy65y72	196	13	infections	infection	NNS
cord-257662-viy65y72	196	14	(	(	-LRB-
cord-257662-viy65y72	196	15	93	93	CD
cord-257662-viy65y72	196	16	)	)	-RRB-
cord-257662-viy65y72	196	17	.	.	.
cord-257662-viy65y72	197	1	Infection	infection	NN
cord-257662-viy65y72	197	2	of	of	IN
cord-257662-viy65y72	197	3	mice	mouse	NNS
cord-257662-viy65y72	197	4	with	with	IN
cord-257662-viy65y72	197	5	the	the	DT
cord-257662-viy65y72	197	6	Arm	Arm	NNP
cord-257662-viy65y72	197	7	strain	strain	NN
cord-257662-viy65y72	197	8	leads	lead	VBZ
cord-257662-viy65y72	197	9	to	to	IN
cord-257662-viy65y72	197	10	a	a	DT
cord-257662-viy65y72	197	11	robust	robust	JJ
cord-257662-viy65y72	197	12	CD8	CD8	NNP
cord-257662-viy65y72	197	13	+	+	CC
cord-257662-viy65y72	197	14	T	T	NNP
cord-257662-viy65y72	197	15	cell	cell	NN
cord-257662-viy65y72	197	16	response	response	NN
cord-257662-viy65y72	197	17	that	that	WDT
cord-257662-viy65y72	197	18	rapidly	rapidly	RB
cord-257662-viy65y72	197	19	clears	clear	VBZ
cord-257662-viy65y72	197	20	the	the	DT
cord-257662-viy65y72	197	21	virus	virus	NN
cord-257662-viy65y72	197	22	(	(	-LRB-
cord-257662-viy65y72	197	23	94	94	CD
cord-257662-viy65y72	197	24	)	)	-RRB-
cord-257662-viy65y72	197	25	,	,	,
cord-257662-viy65y72	197	26	whereas	whereas	IN
cord-257662-viy65y72	197	27	infection	infection	NN
cord-257662-viy65y72	197	28	with	with	IN
cord-257662-viy65y72	197	29	C13	C13	NNP
cord-257662-viy65y72	197	30	results	result	NNS
cord-257662-viy65y72	197	31	in	in	IN
cord-257662-viy65y72	197	32	T	T	NNP
cord-257662-viy65y72	197	33	cells	cell	NNS
cord-257662-viy65y72	197	34	with	with	IN
cord-257662-viy65y72	197	35	impaired	impaired	JJ
cord-257662-viy65y72	197	36	functionality	functionality	NN
cord-257662-viy65y72	197	37	,	,	,
cord-257662-viy65y72	197	38	enabling	enable	VBG
cord-257662-viy65y72	197	39	the	the	DT
cord-257662-viy65y72	197	40	virus	virus	NN
cord-257662-viy65y72	197	41	to	to	TO
cord-257662-viy65y72	197	42	persist	persist	VB
cord-257662-viy65y72	197	43	(	(	-LRB-
cord-257662-viy65y72	197	44	95	95	CD
cord-257662-viy65y72	197	45	)	)	-RRB-
cord-257662-viy65y72	197	46	.	.	.
cord-257662-viy65y72	198	1	It	-PRON-	PRP
cord-257662-viy65y72	198	2	was	be	VBD
cord-257662-viy65y72	198	3	recently	recently	RB
cord-257662-viy65y72	198	4	demonstrated	demonstrate	VBN
cord-257662-viy65y72	198	5	that	that	IN
cord-257662-viy65y72	198	6	C13	C13	NNP
cord-257662-viy65y72	198	7	infection	infection	NN
cord-257662-viy65y72	198	8	led	lead	VBD
cord-257662-viy65y72	198	9	to	to	IN
cord-257662-viy65y72	198	10	an	an	DT
cord-257662-viy65y72	198	11	enhanced	enhanced	JJ
cord-257662-viy65y72	198	12	and	and	CC
cord-257662-viy65y72	198	13	sustained	sustained	JJ
cord-257662-viy65y72	198	14	expansion	expansion	NN
cord-257662-viy65y72	198	15	of	of	IN
cord-257662-viy65y72	198	16	cells	cell	NNS
cord-257662-viy65y72	198	17	that	that	WDT
cord-257662-viy65y72	198	18	resembled	resemble	VBD
cord-257662-viy65y72	198	19	MDSCs	mdsc	NNS
cord-257662-viy65y72	198	20	(	(	-LRB-
cord-257662-viy65y72	198	21	70	70	CD
cord-257662-viy65y72	198	22	)	)	-RRB-
cord-257662-viy65y72	198	23	.	.	.
cord-257662-viy65y72	199	1	These	these	DT
cord-257662-viy65y72	199	2	suppressive	suppressive	JJ
cord-257662-viy65y72	199	3	myeloid	myeloid	NN
cord-257662-viy65y72	199	4	cells	cell	NNS
cord-257662-viy65y72	199	5	inhibited	inhibit	VBD
cord-257662-viy65y72	199	6	T	t	NN
cord-257662-viy65y72	199	7	cell	cell	NN
cord-257662-viy65y72	199	8	proliferation	proliferation	NN
cord-257662-viy65y72	199	9	ex	ex	NN
cord-257662-viy65y72	199	10	vivo	vivo	NN
cord-257662-viy65y72	199	11	via	via	IN
cord-257662-viy65y72	199	12	an	an	DT
cord-257662-viy65y72	199	13	iNOS	inos	NN
cord-257662-viy65y72	199	14	/	/	SYM
cord-257662-viy65y72	199	15	NO	no	NN
cord-257662-viy65y72	199	16	-	-	HYPH
cord-257662-viy65y72	199	17	dependent	dependent	JJ
cord-257662-viy65y72	199	18	but	but	CC
cord-257662-viy65y72	199	19	Arg1-independent	arg1-independent	JJ
cord-257662-viy65y72	199	20	mechanism	mechanism	NN
cord-257662-viy65y72	199	21	.	.	.
cord-257662-viy65y72	200	1	Another	another	DT
cord-257662-viy65y72	200	2	study	study	NN
cord-257662-viy65y72	200	3	,	,	,
cord-257662-viy65y72	200	4	however	however	RB
cord-257662-viy65y72	200	5	,	,	,
cord-257662-viy65y72	200	6	found	find	VBD
cord-257662-viy65y72	200	7	that	that	IN
cord-257662-viy65y72	200	8	Arg1-expressing	arg1-expresse	VBG
cord-257662-viy65y72	200	9	immunoregulatory	immunoregulatory	JJ
cord-257662-viy65y72	200	10	antigen	antigen	NNP
cord-257662-viy65y72	200	11	presenting	present	VBG
cord-257662-viy65y72	200	12	cells	cell	NNS
cord-257662-viy65y72	200	13	induced	induce	VBN
cord-257662-viy65y72	200	14	during	during	IN
cord-257662-viy65y72	200	15	C13	C13	NNP
cord-257662-viy65y72	200	16	infection	infection	NN
cord-257662-viy65y72	200	17	suppressed	suppress	VBD
cord-257662-viy65y72	200	18	T	t	NN
cord-257662-viy65y72	200	19	cell	cell	NN
cord-257662-viy65y72	200	20	responses	response	NNS
cord-257662-viy65y72	200	21	(	(	-LRB-
cord-257662-viy65y72	200	22	67	67	CD
cord-257662-viy65y72	200	23	)	)	-RRB-
cord-257662-viy65y72	200	24	.	.	.
cord-257662-viy65y72	201	1	Most	most	RBS
cord-257662-viy65y72	201	2	recently	recently	RB
cord-257662-viy65y72	201	3	,	,	,
cord-257662-viy65y72	201	4	it	-PRON-	PRP
cord-257662-viy65y72	201	5	was	be	VBD
cord-257662-viy65y72	201	6	demonstrated	demonstrate	VBN
cord-257662-viy65y72	201	7	that	that	IN
cord-257662-viy65y72	201	8	T	t	NN
cord-257662-viy65y72	201	9	cell	cell	NN
cord-257662-viy65y72	201	10	responses	response	NNS
cord-257662-viy65y72	201	11	were	be	VBD
cord-257662-viy65y72	201	12	improved	improve	VBN
cord-257662-viy65y72	201	13	-resulting	-resulte	VBG
cord-257662-viy65y72	201	14	in	in	IN
cord-257662-viy65y72	201	15	clearance	clearance	NN
cord-257662-viy65y72	201	16	of	of	IN
cord-257662-viy65y72	201	17	the	the	DT
cord-257662-viy65y72	201	18	normally	normally	RB
cord-257662-viy65y72	201	19	chronic	chronic	JJ
cord-257662-viy65y72	201	20	C13	C13	NNP
cord-257662-viy65y72	201	21	infection	infection	NN
cord-257662-viy65y72	201	22	-when	-when	.
cord-257662-viy65y72	202	1	either	either	DT
cord-257662-viy65y72	202	2	myeloid	myeloid	NN
cord-257662-viy65y72	202	3	cells	cell	NNS
cord-257662-viy65y72	202	4	or	or	CC
cord-257662-viy65y72	202	5	T	t	NN
cord-257662-viy65y72	202	6	cells	cell	NNS
cord-257662-viy65y72	202	7	lacked	lack	VBD
cord-257662-viy65y72	202	8	IL-10	IL-10	NNP
cord-257662-viy65y72	202	9	production	production	NN
cord-257662-viy65y72	202	10	(	(	-LRB-
cord-257662-viy65y72	202	11	96	96	CD
cord-257662-viy65y72	202	12	)	)	-RRB-
cord-257662-viy65y72	202	13	.	.	.
cord-257662-viy65y72	203	1	Overall	overall	RB
cord-257662-viy65y72	203	2	,	,	,
cord-257662-viy65y72	203	3	these	these	DT
cord-257662-viy65y72	203	4	data	datum	NNS
cord-257662-viy65y72	203	5	demonstrate	demonstrate	VBP
cord-257662-viy65y72	203	6	the	the	DT
cord-257662-viy65y72	203	7	importance	importance	NN
cord-257662-viy65y72	203	8	of	of	IN
cord-257662-viy65y72	203	9	iNOS	inos	CD
cord-257662-viy65y72	203	10	/	/	SYM
cord-257662-viy65y72	203	11	Arg1-expressing	Arg1-expressing	NNP
cord-257662-viy65y72	203	12	myeloid	myeloid	NN
cord-257662-viy65y72	203	13	cells	cell	NNS
cord-257662-viy65y72	203	14	in	in	IN
cord-257662-viy65y72	203	15	viral	viral	JJ
cord-257662-viy65y72	203	16	persistence	persistence	NN
cord-257662-viy65y72	203	17	.	.	.
cord-257662-viy65y72	204	1	Similar	similar	JJ
cord-257662-viy65y72	204	2	to	to	IN
cord-257662-viy65y72	204	3	LCMV	LCMV	NNP
cord-257662-viy65y72	204	4	C13	C13	NNP
cord-257662-viy65y72	204	5	infection	infection	NN
cord-257662-viy65y72	204	6	,	,	,
cord-257662-viy65y72	204	7	it	-PRON-	PRP
cord-257662-viy65y72	204	8	was	be	VBD
cord-257662-viy65y72	204	9	recently	recently	RB
cord-257662-viy65y72	204	10	demonstrated	demonstrate	VBN
cord-257662-viy65y72	204	11	that	that	IN
cord-257662-viy65y72	204	12	infection	infection	NN
cord-257662-viy65y72	204	13	of	of	IN
cord-257662-viy65y72	204	14	mice	mouse	NNS
cord-257662-viy65y72	204	15	with	with	IN
cord-257662-viy65y72	204	16	the	the	DT
cord-257662-viy65y72	204	17	arthritogenic	arthritogenic	NNP
cord-257662-viy65y72	204	18	alphaviruses	alphaviruses	NNP
cord-257662-viy65y72	204	19	Ross	Ross	NNP
cord-257662-viy65y72	204	20	River	River	NNP
cord-257662-viy65y72	204	21	virus	virus	NN
cord-257662-viy65y72	204	22	(	(	-LRB-
cord-257662-viy65y72	204	23	RRV	RRV	NNP
cord-257662-viy65y72	204	24	)	)	-RRB-
cord-257662-viy65y72	204	25	and	and	CC
cord-257662-viy65y72	204	26	chikungunya	chikungunya	NN
cord-257662-viy65y72	204	27	virus	virus	NN
cord-257662-viy65y72	204	28	(	(	-LRB-
cord-257662-viy65y72	204	29	CHIKV	CHIKV	NNP
cord-257662-viy65y72	204	30	)	)	-RRB-
cord-257662-viy65y72	204	31	resulted	result	VBD
cord-257662-viy65y72	204	32	in	in	IN
cord-257662-viy65y72	204	33	the	the	DT
cord-257662-viy65y72	204	34	induction	induction	NN
cord-257662-viy65y72	204	35	of	of	IN
cord-257662-viy65y72	204	36	Arg1	Arg1	NNP
cord-257662-viy65y72	204	37	in	in	IN
cord-257662-viy65y72	204	38	macrophages	macrophage	NNS
cord-257662-viy65y72	204	39	in	in	IN
cord-257662-viy65y72	204	40	the	the	DT
cord-257662-viy65y72	204	41	infected	infected	JJ
cord-257662-viy65y72	204	42	and	and	CC
cord-257662-viy65y72	204	43	inflamed	inflamed	JJ
cord-257662-viy65y72	204	44	musculoskeletal	musculoskeletal	JJ
cord-257662-viy65y72	204	45	tissues	tissue	NNS
cord-257662-viy65y72	204	46	(	(	-LRB-
cord-257662-viy65y72	204	47	69	69	CD
cord-257662-viy65y72	204	48	)	)	-RRB-
cord-257662-viy65y72	204	49	.	.	.
cord-257662-viy65y72	205	1	It	-PRON-	PRP
cord-257662-viy65y72	205	2	was	be	VBD
cord-257662-viy65y72	205	3	further	further	RB
cord-257662-viy65y72	205	4	shown	show	VBN
cord-257662-viy65y72	205	5	that	that	IN
cord-257662-viy65y72	205	6	genetic	genetic	JJ
cord-257662-viy65y72	205	7	deletion	deletion	NN
cord-257662-viy65y72	205	8	of	of	IN
cord-257662-viy65y72	205	9	myeloid	myeloid	JJ
cord-257662-viy65y72	205	10	cell	cell	NN
cord-257662-viy65y72	205	11	Arg1	Arg1	NNP
cord-257662-viy65y72	205	12	resulted	result	VBD
cord-257662-viy65y72	205	13	in	in	IN
cord-257662-viy65y72	205	14	enhanced	enhance	VBN
cord-257662-viy65y72	205	15	viral	viral	JJ
cord-257662-viy65y72	205	16	control	control	NN
cord-257662-viy65y72	205	17	in	in	IN
cord-257662-viy65y72	205	18	inflamed	inflamed	JJ
cord-257662-viy65y72	205	19	muscle	muscle	NN
cord-257662-viy65y72	205	20	tissue	tissue	NN
cord-257662-viy65y72	205	21	and	and	CC
cord-257662-viy65y72	205	22	reduced	reduce	VBN
cord-257662-viy65y72	205	23	tissue	tissue	NN
cord-257662-viy65y72	205	24	pathology	pathology	NN
cord-257662-viy65y72	205	25	following	follow	VBG
cord-257662-viy65y72	205	26	RRV	RRV	NNP
cord-257662-viy65y72	205	27	infection	infection	NN
cord-257662-viy65y72	205	28	in	in	IN
cord-257662-viy65y72	205	29	mice	mouse	NNS
cord-257662-viy65y72	205	30	(	(	-LRB-
cord-257662-viy65y72	205	31	69	69	CD
cord-257662-viy65y72	205	32	)	)	-RRB-
cord-257662-viy65y72	205	33	,	,	,
cord-257662-viy65y72	205	34	suggesting	suggest	VBG
cord-257662-viy65y72	205	35	an	an	DT
cord-257662-viy65y72	205	36	important	important	JJ
cord-257662-viy65y72	205	37	role	role	NN
cord-257662-viy65y72	205	38	for	for	IN
cord-257662-viy65y72	205	39	Arg1-expressing	arg1-expresse	VBG
cord-257662-viy65y72	205	40	macrophages	macrophage	NNS
cord-257662-viy65y72	205	41	in	in	IN
cord-257662-viy65y72	205	42	the	the	DT
cord-257662-viy65y72	205	43	persistence	persistence	NN
cord-257662-viy65y72	205	44	of	of	IN
cord-257662-viy65y72	205	45	these	these	DT
cord-257662-viy65y72	205	46	chronic	chronic	JJ
cord-257662-viy65y72	205	47	viruses	virus	NNS
cord-257662-viy65y72	205	48	.	.	.
cord-257662-viy65y72	206	1	Infection	infection	NN
cord-257662-viy65y72	206	2	of	of	IN
cord-257662-viy65y72	206	3	mice	mouse	NNS
cord-257662-viy65y72	206	4	with	with	IN
cord-257662-viy65y72	206	5	Theiler	Theiler	NNP
cord-257662-viy65y72	206	6	's	's	POS
cord-257662-viy65y72	206	7	murine	murine	JJ
cord-257662-viy65y72	206	8	encephalomyelitis	encephalomyelitis	NN
cord-257662-viy65y72	206	9	virus	virus	NN
cord-257662-viy65y72	206	10	(	(	-LRB-
cord-257662-viy65y72	206	11	TMEV	TMEV	NNP
cord-257662-viy65y72	206	12	)	)	-RRB-
cord-257662-viy65y72	206	13	results	result	VBZ
cord-257662-viy65y72	206	14	in	in	IN
cord-257662-viy65y72	206	15	persistent	persistent	JJ
cord-257662-viy65y72	206	16	virus	virus	NN
cord-257662-viy65y72	206	17	infection	infection	NN
cord-257662-viy65y72	206	18	in	in	IN
cord-257662-viy65y72	206	19	the	the	DT
cord-257662-viy65y72	206	20	CNS	CNS	NNP
cord-257662-viy65y72	206	21	,	,	,
cord-257662-viy65y72	206	22	which	which	WDT
cord-257662-viy65y72	206	23	contributes	contribute	VBZ
cord-257662-viy65y72	206	24	to	to	IN
cord-257662-viy65y72	206	25	the	the	DT
cord-257662-viy65y72	206	26	development	development	NN
cord-257662-viy65y72	206	27	of	of	IN
cord-257662-viy65y72	206	28	a	a	DT
cord-257662-viy65y72	206	29	demyelinating	demyelinating	JJ
cord-257662-viy65y72	206	30	disease	disease	NN
cord-257662-viy65y72	206	31	that	that	WDT
cord-257662-viy65y72	206	32	has	have	VBZ
cord-257662-viy65y72	206	33	similarities	similarity	NNS
cord-257662-viy65y72	206	34	with	with	IN
cord-257662-viy65y72	206	35	multiple	multiple	JJ
cord-257662-viy65y72	206	36	sclerosis	sclerosis	NN
cord-257662-viy65y72	206	37	.	.	.
cord-257662-viy65y72	207	1	Bowen	Bowen	NNP
cord-257662-viy65y72	207	2	and	and	CC
cord-257662-viy65y72	207	3	Olson	Olson	NNP
cord-257662-viy65y72	207	4	(	(	-LRB-
cord-257662-viy65y72	207	5	97	97	CD
cord-257662-viy65y72	207	6	)	)	-RRB-
cord-257662-viy65y72	207	7	showed	show	VBD
cord-257662-viy65y72	207	8	that	that	IN
cord-257662-viy65y72	207	9	CD11b	CD11b	NNS
cord-257662-viy65y72	207	10	+	+	CC
cord-257662-viy65y72	207	11	Ly-6C	ly-6c	NN
cord-257662-viy65y72	207	12	+	+	CC
cord-257662-viy65y72	207	13	cells	cell	NNS
cord-257662-viy65y72	207	14	infiltrated	infiltrate	VBD
cord-257662-viy65y72	207	15	the	the	DT
cord-257662-viy65y72	207	16	CNS	CNS	NNP
cord-257662-viy65y72	207	17	following	follow	VBG
cord-257662-viy65y72	207	18	infection	infection	NN
cord-257662-viy65y72	207	19	and	and	CC
cord-257662-viy65y72	207	20	were	be	VBD
cord-257662-viy65y72	207	21	the	the	DT
cord-257662-viy65y72	207	22	dominant	dominant	JJ
cord-257662-viy65y72	207	23	cell	cell	NN
cord-257662-viy65y72	207	24	type	type	NN
cord-257662-viy65y72	207	25	during	during	IN
cord-257662-viy65y72	207	26	the	the	DT
cord-257662-viy65y72	207	27	innate	innate	JJ
cord-257662-viy65y72	207	28	immune	immune	JJ
cord-257662-viy65y72	207	29	response	response	NN
cord-257662-viy65y72	207	30	.	.	.
cord-257662-viy65y72	208	1	Depletion	depletion	NN
cord-257662-viy65y72	208	2	of	of	IN
cord-257662-viy65y72	208	3	the	the	DT
cord-257662-viy65y72	208	4	CD11b	CD11b	NNS
cord-257662-viy65y72	208	5	+	+	CC
cord-257662-viy65y72	208	6	Ly-6C	ly-6c	NN
cord-257662-viy65y72	208	7	+	+	CC
cord-257662-viy65y72	208	8	cells	cell	NNS
cord-257662-viy65y72	208	9	via	via	IN
cord-257662-viy65y72	208	10	administration	administration	NN
cord-257662-viy65y72	208	11	of	of	IN
cord-257662-viy65y72	208	12	an	an	DT
cord-257662-viy65y72	208	13	anti	anti	JJ
cord-257662-viy65y72	208	14	-	-	JJ
cord-257662-viy65y72	208	15	GR-1	GR-1	NNP
cord-257662-viy65y72	208	16	Ab	Ab	NNP
cord-257662-viy65y72	208	17	resulted	result	VBD
cord-257662-viy65y72	208	18	in	in	IN
cord-257662-viy65y72	208	19	reduced	reduce	VBN
cord-257662-viy65y72	208	20	development	development	NN
cord-257662-viy65y72	208	21	of	of	IN
cord-257662-viy65y72	208	22	demyelinating	demyelinate	VBG
cord-257662-viy65y72	208	23	disease	disease	NN
cord-257662-viy65y72	208	24	and	and	CC
cord-257662-viy65y72	208	25	enhanced	enhanced	JJ
cord-257662-viy65y72	208	26	virus	virus	NN
cord-257662-viy65y72	208	27	-	-	HYPH
cord-257662-viy65y72	208	28	specific	specific	JJ
cord-257662-viy65y72	208	29	CD4	CD4	NNP
cord-257662-viy65y72	208	30	+	+	CC
cord-257662-viy65y72	208	31	and	and	CC
cord-257662-viy65y72	208	32	CD8	CD8	NNP
cord-257662-viy65y72	208	33	+	+	CC
cord-257662-viy65y72	208	34	T	T	NNP
cord-257662-viy65y72	208	35	cell	cell	NN
cord-257662-viy65y72	208	36	responses	response	NNS
cord-257662-viy65y72	208	37	(	(	-LRB-
cord-257662-viy65y72	208	38	97	97	CD
cord-257662-viy65y72	208	39	)	)	-RRB-
cord-257662-viy65y72	208	40	.	.	.
cord-257662-viy65y72	209	1	Additionally	additionally	RB
cord-257662-viy65y72	209	2	,	,	,
cord-257662-viy65y72	209	3	TMEV	TMEV	NNP
cord-257662-viy65y72	209	4	-	-	HYPH
cord-257662-viy65y72	209	5	infected	infect	VBN
cord-257662-viy65y72	209	6	,	,	,
cord-257662-viy65y72	209	7	anti	anti	JJ
cord-257662-viy65y72	209	8	-	-	JJ
cord-257662-viy65y72	209	9	GR-1	gr-1	JJ
cord-257662-viy65y72	209	10	Ab	ab	NN
cord-257662-viy65y72	209	11	-	-	HYPH
cord-257662-viy65y72	209	12	treated	treat	VBN
cord-257662-viy65y72	209	13	mice	mouse	NNS
cord-257662-viy65y72	209	14	had	have	VBD
cord-257662-viy65y72	209	15	decreased	decrease	VBN
cord-257662-viy65y72	209	16	myelin	myelin	NN
cord-257662-viy65y72	209	17	-	-	HYPH
cord-257662-viy65y72	209	18	specific	specific	JJ
cord-257662-viy65y72	209	19	CD4	CD4	NNP
cord-257662-viy65y72	209	20	+	+	CC
cord-257662-viy65y72	209	21	T	t	NN
cord-257662-viy65y72	209	22	cell	cell	NN
cord-257662-viy65y72	209	23	responses	response	NNS
cord-257662-viy65y72	209	24	compared	compare	VBN
cord-257662-viy65y72	209	25	to	to	TO
cord-257662-viy65y72	209	26	control	control	VB
cord-257662-viy65y72	209	27	Ab	Ab	NNP
cord-257662-viy65y72	209	28	-	-	HYPH
cord-257662-viy65y72	209	29	treated	treat	VBN
cord-257662-viy65y72	209	30	mice	mouse	NNS
cord-257662-viy65y72	209	31	during	during	IN
cord-257662-viy65y72	209	32	the	the	DT
cord-257662-viy65y72	209	33	demyelinating	demyelinating	JJ
cord-257662-viy65y72	209	34	disease	disease	NN
cord-257662-viy65y72	209	35	at	at	IN
cord-257662-viy65y72	209	36	a	a	DT
cord-257662-viy65y72	209	37	later	later	JJ
cord-257662-viy65y72	209	38	time	time	NN
cord-257662-viy65y72	209	39	post	post	NN
cord-257662-viy65y72	209	40	-	-	NN
cord-257662-viy65y72	209	41	infection	infection	JJ
cord-257662-viy65y72	209	42	(	(	-LRB-
cord-257662-viy65y72	209	43	97	97	CD
cord-257662-viy65y72	209	44	)	)	-RRB-
cord-257662-viy65y72	209	45	.	.	.
cord-257662-viy65y72	210	1	Although	although	IN
cord-257662-viy65y72	210	2	the	the	DT
cord-257662-viy65y72	210	3	expression	expression	NN
cord-257662-viy65y72	210	4	of	of	IN
cord-257662-viy65y72	210	5	Arg1	Arg1	NNP
cord-257662-viy65y72	210	6	was	be	VBD
cord-257662-viy65y72	210	7	not	not	RB
cord-257662-viy65y72	210	8	investigated	investigate	VBN
cord-257662-viy65y72	210	9	in	in	IN
cord-257662-viy65y72	210	10	this	this	DT
cord-257662-viy65y72	210	11	study	study	NN
cord-257662-viy65y72	210	12	,	,	,
cord-257662-viy65y72	210	13	TMEVinfected	tmevinfecte	VBN
cord-257662-viy65y72	210	14	mice	mouse	NNS
cord-257662-viy65y72	210	15	had	have	VBD
cord-257662-viy65y72	210	16	elevated	elevate	VBN
cord-257662-viy65y72	210	17	expression	expression	NN
cord-257662-viy65y72	210	18	of	of	IN
cord-257662-viy65y72	210	19	IL-10	IL-10	NNP
cord-257662-viy65y72	210	20	in	in	IN
cord-257662-viy65y72	210	21	the	the	DT
cord-257662-viy65y72	210	22	brain	brain	NN
cord-257662-viy65y72	210	23	and	and	CC
cord-257662-viy65y72	210	24	spinal	spinal	JJ
cord-257662-viy65y72	210	25	cord	cord	NN
cord-257662-viy65y72	210	26	(	(	-LRB-
cord-257662-viy65y72	210	27	97	97	CD
cord-257662-viy65y72	210	28	)	)	-RRB-
cord-257662-viy65y72	210	29	,	,	,
cord-257662-viy65y72	210	30	suggesting	suggest	VBG
cord-257662-viy65y72	210	31	a	a	DT
cord-257662-viy65y72	210	32	role	role	NN
cord-257662-viy65y72	210	33	for	for	IN
cord-257662-viy65y72	210	34	this	this	DT
cord-257662-viy65y72	210	35	cytokine	cytokine	NN
cord-257662-viy65y72	210	36	in	in	IN
cord-257662-viy65y72	210	37	the	the	DT
cord-257662-viy65y72	210	38	suppression	suppression	NN
cord-257662-viy65y72	210	39	of	of	IN
cord-257662-viy65y72	210	40	antiviral	antiviral	JJ
cord-257662-viy65y72	210	41	T	T	NNP
cord-257662-viy65y72	210	42	cell	cell	NN
cord-257662-viy65y72	210	43	responses	response	NNS
cord-257662-viy65y72	210	44	,	,	,
cord-257662-viy65y72	210	45	potentially	potentially	RB
cord-257662-viy65y72	210	46	through	through	IN
cord-257662-viy65y72	210	47	the	the	DT
cord-257662-viy65y72	210	48	effects	effect	NNS
cord-257662-viy65y72	210	49	of	of	IN
cord-257662-viy65y72	210	50	Arg1	Arg1	NNP
cord-257662-viy65y72	210	51	.	.	.
cord-257662-viy65y72	211	1	Interestingly	interestingly	RB
cord-257662-viy65y72	211	2	,	,	,
cord-257662-viy65y72	211	3	a	a	DT
cord-257662-viy65y72	211	4	role	role	NN
cord-257662-viy65y72	211	5	for	for	IN
cord-257662-viy65y72	211	6	the	the	DT
cord-257662-viy65y72	211	7	modulation	modulation	NN
cord-257662-viy65y72	211	8	of	of	IN
cord-257662-viy65y72	211	9	arginine	arginine	NN
cord-257662-viy65y72	211	10	metabolism	metabolism	NN
cord-257662-viy65y72	211	11	in	in	IN
cord-257662-viy65y72	211	12	viral	viral	JJ
cord-257662-viy65y72	211	13	control	control	NN
cord-257662-viy65y72	211	14	versus	versus	IN
cord-257662-viy65y72	211	15	persistence	persistence	NN
cord-257662-viy65y72	211	16	along	along	IN
cord-257662-viy65y72	211	17	with	with	IN
cord-257662-viy65y72	211	18	associated	associated	JJ
cord-257662-viy65y72	211	19	disease	disease	NN
cord-257662-viy65y72	211	20	has	have	VBZ
cord-257662-viy65y72	211	21	recently	recently	RB
cord-257662-viy65y72	211	22	been	be	VBN
cord-257662-viy65y72	211	23	demonstrated	demonstrate	VBN
cord-257662-viy65y72	211	24	for	for	IN
cord-257662-viy65y72	211	25	the	the	DT
cord-257662-viy65y72	211	26	tumor	tumor	NN
cord-257662-viy65y72	211	27	-	-	HYPH
cord-257662-viy65y72	211	28	inducing	induce	VBG
cord-257662-viy65y72	211	29	,	,	,
cord-257662-viy65y72	211	30	chickenspecific	chickenspecific	JJ
cord-257662-viy65y72	211	31	herpesvirus	herpesvirus	NN
cord-257662-viy65y72	211	32	MDV	MDV	NNP
cord-257662-viy65y72	211	33	.	.	.
cord-257662-viy65y72	212	1	We	-PRON-	PRP
cord-257662-viy65y72	212	2	mentioned	mention	VBD
cord-257662-viy65y72	212	3	above	above	IN
cord-257662-viy65y72	212	4	that	that	DT
cord-257662-viy65y72	212	5	MDV	MDV	NNP
cord-257662-viy65y72	212	6	was	be	VBD
cord-257662-viy65y72	212	7	vulnerable	vulnerable	JJ
cord-257662-viy65y72	212	8	to	to	IN
cord-257662-viy65y72	212	9	the	the	DT
cord-257662-viy65y72	212	10	antiviral	antiviral	JJ
cord-257662-viy65y72	212	11	properties	property	NNS
cord-257662-viy65y72	212	12	of	of	IN
cord-257662-viy65y72	212	13	NO	NO	NNP
cord-257662-viy65y72	212	14	,	,	,
cord-257662-viy65y72	212	15	with	with	IN
cord-257662-viy65y72	212	16	iNOS	inos	JJ
cord-257662-viy65y72	212	17	being	be	VBG
cord-257662-viy65y72	212	18	induced	induce	VBN
cord-257662-viy65y72	212	19	in	in	IN
cord-257662-viy65y72	212	20	genetically	genetically	RB
cord-257662-viy65y72	212	21	resistant	resistant	JJ
cord-257662-viy65y72	212	22	chickens	chicken	NNS
cord-257662-viy65y72	212	23	and	and	CC
cord-257662-viy65y72	212	24	in	in	IN
cord-257662-viy65y72	212	25	vaccinated	vaccinated	JJ
cord-257662-viy65y72	212	26	chickens	chicken	NNS
cord-257662-viy65y72	212	27	(	(	-LRB-
cord-257662-viy65y72	212	28	35	35	CD
cord-257662-viy65y72	212	29	)	)	-RRB-
cord-257662-viy65y72	212	30	.	.	.
cord-257662-viy65y72	213	1	In	in	IN
cord-257662-viy65y72	213	2	contrast	contrast	NN
cord-257662-viy65y72	213	3	,	,	,
cord-257662-viy65y72	213	4	MDV	MDV	NNP
cord-257662-viy65y72	213	5	induced	induce	VBD
cord-257662-viy65y72	213	6	strong	strong	JJ
cord-257662-viy65y72	213	7	macrophage	macrophage	NN
cord-257662-viy65y72	213	8	arginase	arginase	NN
cord-257662-viy65y72	213	9	activity	activity	NN
cord-257662-viy65y72	213	10	in	in	IN
cord-257662-viy65y72	213	11	cell	cell	NN
cord-257662-viy65y72	213	12	extracts	extract	NNS
cord-257662-viy65y72	213	13	from	from	IN
cord-257662-viy65y72	213	14	adherent	adherent	JJ
cord-257662-viy65y72	213	15	monocytes	monocyte	NNS
cord-257662-viy65y72	213	16	from	from	IN
cord-257662-viy65y72	213	17	genetically	genetically	RB
cord-257662-viy65y72	213	18	susceptible	susceptible	JJ
cord-257662-viy65y72	213	19	chickens	chicken	NNS
cord-257662-viy65y72	213	20	,	,	,
cord-257662-viy65y72	213	21	but	but	CC
cord-257662-viy65y72	213	22	not	not	RB
cord-257662-viy65y72	213	23	in	in	IN
cord-257662-viy65y72	213	24	chickens	chicken	NNS
cord-257662-viy65y72	213	25	that	that	WDT
cord-257662-viy65y72	213	26	were	be	VBD
cord-257662-viy65y72	213	27	resistant	resistant	JJ
cord-257662-viy65y72	213	28	to	to	IN
cord-257662-viy65y72	213	29	Marek	Marek	NNP
cord-257662-viy65y72	213	30	's	's	POS
cord-257662-viy65y72	213	31	disease	disease	NN
cord-257662-viy65y72	213	32	,	,	,
cord-257662-viy65y72	213	33	either	either	CC
cord-257662-viy65y72	213	34	genetically	genetically	RB
cord-257662-viy65y72	213	35	or	or	CC
cord-257662-viy65y72	213	36	acquired	acquire	VBN
cord-257662-viy65y72	213	37	after	after	IN
cord-257662-viy65y72	213	38	vaccination	vaccination	NN
cord-257662-viy65y72	213	39	(	(	-LRB-
cord-257662-viy65y72	213	40	35	35	CD
cord-257662-viy65y72	213	41	)	)	-RRB-
cord-257662-viy65y72	213	42	.	.	.
cord-257662-viy65y72	214	1	Together	together	RB
cord-257662-viy65y72	214	2	,	,	,
cord-257662-viy65y72	214	3	these	these	DT
cord-257662-viy65y72	214	4	data	datum	NNS
cord-257662-viy65y72	214	5	suggest	suggest	VBP
cord-257662-viy65y72	214	6	that	that	IN
cord-257662-viy65y72	214	7	in	in	IN
cord-257662-viy65y72	214	8	the	the	DT
cord-257662-viy65y72	214	9	case	case	NN
cord-257662-viy65y72	214	10	of	of	IN
cord-257662-viy65y72	214	11	Marek	Marek	NNP
cord-257662-viy65y72	214	12	's	's	POS
cord-257662-viy65y72	214	13	disease	disease	NN
cord-257662-viy65y72	214	14	,	,	,
cord-257662-viy65y72	214	15	the	the	DT
cord-257662-viy65y72	214	16	state	state	NN
cord-257662-viy65y72	214	17	of	of	IN
cord-257662-viy65y72	214	18	resistance	resistance	NN
cord-257662-viy65y72	214	19	versus	versus	IN
cord-257662-viy65y72	214	20	sensitivity	sensitivity	NN
cord-257662-viy65y72	214	21	to	to	IN
cord-257662-viy65y72	214	22	disease	disease	NN
cord-257662-viy65y72	214	23	was	be	VBD
cord-257662-viy65y72	214	24	correlated	correlate	VBN
cord-257662-viy65y72	214	25	with	with	IN
cord-257662-viy65y72	214	26	a	a	DT
cord-257662-viy65y72	214	27	reciprocal	reciprocal	JJ
cord-257662-viy65y72	214	28	balance	balance	NN
cord-257662-viy65y72	214	29	of	of	IN
cord-257662-viy65y72	214	30	NOS	NOS	NNP
cord-257662-viy65y72	214	31	versus	versus	IN
cord-257662-viy65y72	214	32	arginase	arginase	NNP
cord-257662-viy65y72	214	33	activities	activity	NNS
cord-257662-viy65y72	214	34	in	in	IN
cord-257662-viy65y72	214	35	macrophages	macrophage	NNS
cord-257662-viy65y72	214	36	.	.	.
cord-257662-viy65y72	215	1	This	this	DT
cord-257662-viy65y72	215	2	phenomenon	phenomenon	NN
cord-257662-viy65y72	215	3	of	of	IN
cord-257662-viy65y72	215	4	Arg1-mediated	Arg1-mediated	NNP
cord-257662-viy65y72	215	5	T	T	NNP
cord-257662-viy65y72	215	6	cell	cell	NN
cord-257662-viy65y72	215	7	suppression	suppression	NN
cord-257662-viy65y72	215	8	has	have	VBZ
cord-257662-viy65y72	215	9	also	also	RB
cord-257662-viy65y72	215	10	been	be	VBN
cord-257662-viy65y72	215	11	recognized	recognize	VBN
cord-257662-viy65y72	215	12	in	in	IN
cord-257662-viy65y72	215	13	human	human	JJ
cord-257662-viy65y72	215	14	viral	viral	JJ
cord-257662-viy65y72	215	15	infections	infection	NNS
cord-257662-viy65y72	215	16	.	.	.
cord-257662-viy65y72	216	1	Arg1	Arg1	NNP
cord-257662-viy65y72	216	2	mRNA	mRNA	NNP
cord-257662-viy65y72	216	3	and	and	CC
cord-257662-viy65y72	216	4	protein	protein	NN
cord-257662-viy65y72	216	5	levels	level	NNS
cord-257662-viy65y72	216	6	were	be	VBD
cord-257662-viy65y72	216	7	elevated	elevate	VBN
cord-257662-viy65y72	216	8	in	in	IN
cord-257662-viy65y72	216	9	HCV	HCV	NNP
cord-257662-viy65y72	216	10	-	-	HYPH
cord-257662-viy65y72	216	11	infected	infect	VBN
cord-257662-viy65y72	216	12	liver	liver	NN
cord-257662-viy65y72	216	13	cell	cell	NN
cord-257662-viy65y72	216	14	lines	line	NNS
cord-257662-viy65y72	216	15	in	in	IN
cord-257662-viy65y72	216	16	vitro	vitro	FW
cord-257662-viy65y72	216	17	and	and	CC
cord-257662-viy65y72	216	18	in	in	IN
cord-257662-viy65y72	216	19	HCV	HCV	NNP
cord-257662-viy65y72	216	20	-	-	HYPH
cord-257662-viy65y72	216	21	infected	infect	VBN
cord-257662-viy65y72	216	22	liver	liver	NN
cord-257662-viy65y72	216	23	samples	sample	NNS
cord-257662-viy65y72	216	24	compared	compare	VBN
cord-257662-viy65y72	216	25	with	with	IN
cord-257662-viy65y72	216	26	paired	paired	JJ
cord-257662-viy65y72	216	27	hepatocellular	hepatocellular	JJ
cord-257662-viy65y72	216	28	carcinoma	carcinoma	NN
cord-257662-viy65y72	216	29	samples	sample	NNS
cord-257662-viy65y72	216	30	from	from	IN
cord-257662-viy65y72	216	31	the	the	DT
cord-257662-viy65y72	216	32	same	same	JJ
cord-257662-viy65y72	216	33	patients	patient	NNS
cord-257662-viy65y72	216	34	or	or	CC
cord-257662-viy65y72	216	35	with	with	IN
cord-257662-viy65y72	216	36	uninfected	uninfected	JJ
cord-257662-viy65y72	216	37	liver	liver	NN
cord-257662-viy65y72	216	38	tissues	tissue	NNS
cord-257662-viy65y72	216	39	(	(	-LRB-
cord-257662-viy65y72	216	40	71	71	CD
cord-257662-viy65y72	216	41	)	)	-RRB-
cord-257662-viy65y72	216	42	.	.	.
cord-257662-viy65y72	217	1	Additionally	additionally	RB
cord-257662-viy65y72	217	2	,	,	,
cord-257662-viy65y72	217	3	the	the	DT
cord-257662-viy65y72	217	4	number	number	NN
cord-257662-viy65y72	217	5	of	of	IN
cord-257662-viy65y72	217	6	MDSCs	mdsc	NNS
cord-257662-viy65y72	217	7	in	in	IN
cord-257662-viy65y72	217	8	chronic	chronic	JJ
cord-257662-viy65y72	217	9	HCV	HCV	NNP
cord-257662-viy65y72	217	10	patients	patient	NNS
cord-257662-viy65y72	217	11	correlated	correlate	VBN
cord-257662-viy65y72	217	12	with	with	IN
cord-257662-viy65y72	217	13	levels	level	NNS
cord-257662-viy65y72	217	14	of	of	IN
cord-257662-viy65y72	217	15	plasma	plasma	NN
cord-257662-viy65y72	217	16	HCV	HCV	NNP
cord-257662-viy65y72	217	17	-	-	HYPH
cord-257662-viy65y72	217	18	RNA	RNA	NNP
cord-257662-viy65y72	217	19	(	(	-LRB-
cord-257662-viy65y72	217	20	98	98	CD
cord-257662-viy65y72	217	21	)	)	-RRB-
cord-257662-viy65y72	217	22	.	.	.
cord-257662-viy65y72	218	1	Cai	Cai	NNP
cord-257662-viy65y72	218	2	et	et	FW
cord-257662-viy65y72	218	3	al	al	NNP
cord-257662-viy65y72	218	4	.	.	.
cord-257662-viy65y72	219	1	(	(	-LRB-
cord-257662-viy65y72	219	2	98	98	CD
cord-257662-viy65y72	219	3	)	)	-RRB-
cord-257662-viy65y72	219	4	also	also	RB
cord-257662-viy65y72	219	5	found	find	VBD
cord-257662-viy65y72	219	6	that	that	IN
cord-257662-viy65y72	219	7	MDSCs	mdsc	NNS
cord-257662-viy65y72	219	8	from	from	IN
cord-257662-viy65y72	219	9	patients	patient	NNS
cord-257662-viy65y72	219	10	with	with	IN
cord-257662-viy65y72	219	11	chronic	chronic	JJ
cord-257662-viy65y72	219	12	HCV	HCV	NNP
cord-257662-viy65y72	219	13	infection	infection	NN
cord-257662-viy65y72	219	14	suppressed	suppress	VBD
cord-257662-viy65y72	219	15	T	T	NNP
cord-257662-viy65y72	219	16	cell	cell	NN
cord-257662-viy65y72	219	17	function	function	NN
cord-257662-viy65y72	219	18	via	via	IN
cord-257662-viy65y72	219	19	an	an	DT
cord-257662-viy65y72	219	20	Arg1-dependent	arg1-dependent	NN
cord-257662-viy65y72	219	21	mechanism	mechanism	NN
cord-257662-viy65y72	219	22	.	.	.
cord-257662-viy65y72	220	1	An	an	DT
cord-257662-viy65y72	220	2	additional	additional	JJ
cord-257662-viy65y72	220	3	study	study	NN
cord-257662-viy65y72	220	4	found	find	VBD
cord-257662-viy65y72	220	5	that	that	IN
cord-257662-viy65y72	220	6	more	more	JJR
cord-257662-viy65y72	220	7	PBMCs	pbmc	NNS
cord-257662-viy65y72	220	8	from	from	IN
cord-257662-viy65y72	220	9	chronic	chronic	JJ
cord-257662-viy65y72	220	10	HCV	HCV	NNP
cord-257662-viy65y72	220	11	patients	patient	NNS
cord-257662-viy65y72	220	12	expressed	express	VBD
cord-257662-viy65y72	220	13	the	the	DT
cord-257662-viy65y72	220	14	phenotypic	phenotypic	JJ
cord-257662-viy65y72	220	15	markers	marker	NNS
cord-257662-viy65y72	220	16	of	of	IN
cord-257662-viy65y72	220	17	MDSCs	mdsc	NNS
cord-257662-viy65y72	220	18	than	than	IN
cord-257662-viy65y72	220	19	PBMCs	pbmc	NNS
cord-257662-viy65y72	220	20	from	from	IN
cord-257662-viy65y72	220	21	healthy	healthy	JJ
cord-257662-viy65y72	220	22	controls	control	NNS
cord-257662-viy65y72	220	23	,	,	,
cord-257662-viy65y72	220	24	and	and	CC
cord-257662-viy65y72	220	25	these	these	DT
cord-257662-viy65y72	220	26	cells	cell	NNS
cord-257662-viy65y72	220	27	expressed	express	VBD
cord-257662-viy65y72	220	28	increased	increase	VBN
cord-257662-viy65y72	220	29	levels	level	NNS
cord-257662-viy65y72	220	30	of	of	IN
cord-257662-viy65y72	220	31	p47	p47	CD
cord-257662-viy65y72	220	32	phox	phox	NNP
cord-257662-viy65y72	220	33	,	,	,
cord-257662-viy65y72	220	34	a	a	DT
cord-257662-viy65y72	220	35	component	component	NN
cord-257662-viy65y72	220	36	of	of	IN
cord-257662-viy65y72	220	37	the	the	DT
cord-257662-viy65y72	220	38	NADPH	NADPH	NNP
cord-257662-viy65y72	220	39	oxidase	oxidase	NN
cord-257662-viy65y72	220	40	complex	complex	NN
cord-257662-viy65y72	220	41	(	(	-LRB-
cord-257662-viy65y72	220	42	99	99	CD
cord-257662-viy65y72	220	43	)	)	-RRB-
cord-257662-viy65y72	220	44	,	,	,
cord-257662-viy65y72	220	45	suggesting	suggest	VBG
cord-257662-viy65y72	220	46	a	a	DT
cord-257662-viy65y72	220	47	role	role	NN
cord-257662-viy65y72	220	48	for	for	IN
cord-257662-viy65y72	220	49	ROS	ROS	NNP
cord-257662-viy65y72	220	50	in	in	IN
cord-257662-viy65y72	220	51	MDSC	MDSC	NNP
cord-257662-viy65y72	220	52	-	-	HYPH
cord-257662-viy65y72	220	53	mediated	mediate	VBN
cord-257662-viy65y72	220	54	suppression	suppression	NN
cord-257662-viy65y72	220	55	.	.	.
cord-257662-viy65y72	221	1	Consistent	consistent	JJ
cord-257662-viy65y72	221	2	with	with	IN
cord-257662-viy65y72	221	3	this	this	DT
cord-257662-viy65y72	221	4	,	,	,
cord-257662-viy65y72	221	5	CD33	CD33	NNP
cord-257662-viy65y72	221	6	+	+	CC
cord-257662-viy65y72	221	7	mononuclear	mononuclear	NN
cord-257662-viy65y72	221	8	cells	cell	NNS
cord-257662-viy65y72	221	9	co	co	VBD
cord-257662-viy65y72	221	10	-	-	JJ
cord-257662-viy65y72	221	11	cultured	cultured	JJ
cord-257662-viy65y72	221	12	with	with	IN
cord-257662-viy65y72	221	13	HCV	HCV	NNP
cord-257662-viy65y72	221	14	-	-	HYPH
cord-257662-viy65y72	221	15	infected	infect	VBN
cord-257662-viy65y72	221	16	hepatocytes	hepatocyte	NNS
cord-257662-viy65y72	221	17	or	or	CC
cord-257662-viy65y72	221	18	HCV	HCV	NNP
cord-257662-viy65y72	221	19	core	core	NN
cord-257662-viy65y72	221	20	protein	protein	NN
cord-257662-viy65y72	221	21	suppressed	suppress	VBD
cord-257662-viy65y72	221	22	T	t	NN
cord-257662-viy65y72	221	23	cell	cell	NN
cord-257662-viy65y72	221	24	proliferation	proliferation	NN
cord-257662-viy65y72	221	25	in	in	IN
cord-257662-viy65y72	221	26	a	a	DT
cord-257662-viy65y72	221	27	ROS	ROS	NNP
cord-257662-viy65y72	221	28	-	-	HYPH
cord-257662-viy65y72	221	29	dependent	dependent	JJ
cord-257662-viy65y72	221	30	manner	manner	NN
cord-257662-viy65y72	221	31	(	(	-LRB-
cord-257662-viy65y72	221	32	99	99	CD
cord-257662-viy65y72	221	33	)	)	-RRB-
cord-257662-viy65y72	221	34	.	.	.
cord-257662-viy65y72	222	1	Overall	overall	RB
cord-257662-viy65y72	222	2	,	,	,
cord-257662-viy65y72	222	3	these	these	DT
cord-257662-viy65y72	222	4	data	datum	NNS
cord-257662-viy65y72	222	5	suggest	suggest	VBP
cord-257662-viy65y72	222	6	that	that	IN
cord-257662-viy65y72	222	7	multiple	multiple	JJ
cord-257662-viy65y72	222	8	mechanisms	mechanism	NNS
cord-257662-viy65y72	222	9	-including	-include	VBG
cord-257662-viy65y72	223	1	arginine	arginine	NN
cord-257662-viy65y72	223	2	metabolism	metabolism	NN
cord-257662-viy65y72	223	3	and	and	CC
cord-257662-viy65y72	223	4	ROS	ROS	NNP
cord-257662-viy65y72	223	5	-may	-may	-LRB-
cord-257662-viy65y72	223	6	be	be	VB
cord-257662-viy65y72	223	7	at	at	IN
cord-257662-viy65y72	223	8	play	play	NN
cord-257662-viy65y72	223	9	in	in	IN
cord-257662-viy65y72	223	10	myeloid	myeloid	JJ
cord-257662-viy65y72	223	11	cell	cell	NN
cord-257662-viy65y72	223	12	-	-	HYPH
cord-257662-viy65y72	223	13	mediated	mediate	VBN
cord-257662-viy65y72	223	14	suppression	suppression	NN
cord-257662-viy65y72	223	15	of	of	IN
cord-257662-viy65y72	223	16	anti	anti	JJ
cord-257662-viy65y72	223	17	-	-	JJ
cord-257662-viy65y72	223	18	HCV	HCV	NNP
cord-257662-viy65y72	223	19	T	T	NNP
cord-257662-viy65y72	223	20	cell	cell	NN
cord-257662-viy65y72	223	21	responses	response	NNS
cord-257662-viy65y72	223	22	.	.	.
cord-257662-viy65y72	224	1	It	-PRON-	PRP
cord-257662-viy65y72	224	2	has	have	VBZ
cord-257662-viy65y72	224	3	been	be	VBN
cord-257662-viy65y72	224	4	suggested	suggest	VBN
cord-257662-viy65y72	224	5	that	that	IN
cord-257662-viy65y72	224	6	prolonged	prolong	VBN
cord-257662-viy65y72	224	7	immune	immune	JJ
cord-257662-viy65y72	224	8	activation	activation	NN
cord-257662-viy65y72	224	9	during	during	IN
cord-257662-viy65y72	224	10	chronic	chronic	JJ
cord-257662-viy65y72	224	11	virus	virus	NN
cord-257662-viy65y72	224	12	infections	infection	NNS
cord-257662-viy65y72	224	13	,	,	,
cord-257662-viy65y72	224	14	such	such	JJ
cord-257662-viy65y72	224	15	as	as	IN
cord-257662-viy65y72	224	16	HCV	HCV	NNP
cord-257662-viy65y72	224	17	and	and	CC
cord-257662-viy65y72	224	18	HIV	HIV	NNP
cord-257662-viy65y72	224	19	,	,	,
cord-257662-viy65y72	224	20	provides	provide	VBZ
cord-257662-viy65y72	224	21	an	an	DT
cord-257662-viy65y72	224	22	environment	environment	NN
cord-257662-viy65y72	224	23	that	that	WDT
cord-257662-viy65y72	224	24	drives	drive	VBZ
cord-257662-viy65y72	224	25	viral	viral	JJ
cord-257662-viy65y72	224	26	replication	replication	NN
cord-257662-viy65y72	224	27	and	and	CC
cord-257662-viy65y72	224	28	disease	disease	NN
cord-257662-viy65y72	224	29	progression	progression	NN
cord-257662-viy65y72	224	30	(	(	-LRB-
cord-257662-viy65y72	224	31	100	100	CD
cord-257662-viy65y72	224	32	,	,	,
cord-257662-viy65y72	224	33	101	101	CD
cord-257662-viy65y72	224	34	)	)	-RRB-
cord-257662-viy65y72	224	35	.	.	.
cord-257662-viy65y72	225	1	Moreover	moreover	RB
cord-257662-viy65y72	225	2	,	,	,
cord-257662-viy65y72	225	3	immune	immune	JJ
cord-257662-viy65y72	225	4	activation	activation	NN
cord-257662-viy65y72	225	5	can	can	MD
cord-257662-viy65y72	225	6	drive	drive	VB
cord-257662-viy65y72	225	7	an	an	DT
cord-257662-viy65y72	225	8	anti	anti	JJ
cord-257662-viy65y72	225	9	-	-	JJ
cord-257662-viy65y72	225	10	inflammatory	inflammatory	JJ
cord-257662-viy65y72	225	11	response	response	NN
cord-257662-viy65y72	225	12	to	to	TO
cord-257662-viy65y72	225	13	limit	limit	VB
cord-257662-viy65y72	225	14	immunopathology	immunopathology	NN
cord-257662-viy65y72	225	15	,	,	,
cord-257662-viy65y72	225	16	which	which	WDT
cord-257662-viy65y72	225	17	can	can	MD
cord-257662-viy65y72	225	18	be	be	VB
cord-257662-viy65y72	225	19	characterized	characterize	VBN
cord-257662-viy65y72	225	20	by	by	IN
cord-257662-viy65y72	225	21	the	the	DT
cord-257662-viy65y72	225	22	presence	presence	NN
cord-257662-viy65y72	225	23	of	of	IN
cord-257662-viy65y72	225	24	M2-like	M2-like	NNS
cord-257662-viy65y72	225	25	macrophages	macrophage	NNS
cord-257662-viy65y72	225	26	.	.	.
cord-257662-viy65y72	226	1	Indeed	indeed	RB
cord-257662-viy65y72	226	2	,	,	,
cord-257662-viy65y72	226	3	similar	similar	JJ
cord-257662-viy65y72	226	4	to	to	IN
cord-257662-viy65y72	226	5	HCV	HCV	NNP
cord-257662-viy65y72	226	6	infection	infection	NN
cord-257662-viy65y72	226	7	,	,	,
cord-257662-viy65y72	226	8	a	a	DT
cord-257662-viy65y72	226	9	role	role	NN
cord-257662-viy65y72	226	10	for	for	IN
cord-257662-viy65y72	226	11	arginase	arginase	NNP
cord-257662-viy65y72	226	12	and	and	CC
cord-257662-viy65y72	226	13	M2polarized	M2polarized	NNP
cord-257662-viy65y72	226	14	MDSC	MDSC	NNP
cord-257662-viy65y72	226	15	-	-	HYPH
cord-257662-viy65y72	226	16	like	like	JJ
cord-257662-viy65y72	226	17	cells	cell	NNS
cord-257662-viy65y72	226	18	has	have	VBZ
cord-257662-viy65y72	226	19	been	be	VBN
cord-257662-viy65y72	226	20	identified	identify	VBN
cord-257662-viy65y72	226	21	in	in	IN
cord-257662-viy65y72	226	22	the	the	DT
cord-257662-viy65y72	226	23	suppression	suppression	NN
cord-257662-viy65y72	226	24	of	of	IN
cord-257662-viy65y72	226	25	antiviral	antiviral	JJ
cord-257662-viy65y72	226	26	T	T	NNP
cord-257662-viy65y72	226	27	cell	cell	NN
cord-257662-viy65y72	226	28	responses	response	NNS
cord-257662-viy65y72	226	29	following	follow	VBG
cord-257662-viy65y72	226	30	HIV	HIV	NNP
cord-257662-viy65y72	226	31	infection	infection	NN
cord-257662-viy65y72	226	32	.	.	.
cord-257662-viy65y72	227	1	Individuals	individual	NNS
cord-257662-viy65y72	227	2	with	with	IN
cord-257662-viy65y72	227	3	detectable	detectable	JJ
cord-257662-viy65y72	227	4	HIV-1	HIV-1	NNP
cord-257662-viy65y72	227	5	infection	infection	NN
cord-257662-viy65y72	227	6	showed	show	VBD
cord-257662-viy65y72	227	7	an	an	DT
cord-257662-viy65y72	227	8	increase	increase	NN
cord-257662-viy65y72	227	9	in	in	IN
cord-257662-viy65y72	227	10	the	the	DT
cord-257662-viy65y72	227	11	frequency	frequency	NN
cord-257662-viy65y72	227	12	of	of	IN
cord-257662-viy65y72	227	13	CD163	CD163	NNP
cord-257662-viy65y72	227	14	+	+	CC
cord-257662-viy65y72	227	15	CD16	CD16	NNP
cord-257662-viy65y72	227	16	+	+	CC
cord-257662-viy65y72	227	17	CD14	CD14	NNP
cord-257662-viy65y72	227	18	+	+	CC
cord-257662-viy65y72	227	19	monocytes	monocyte	NNS
cord-257662-viy65y72	227	20	,	,	,
cord-257662-viy65y72	227	21	which	which	WDT
cord-257662-viy65y72	227	22	are	be	VBP
cord-257662-viy65y72	227	23	thought	think	VBN
cord-257662-viy65y72	227	24	to	to	TO
cord-257662-viy65y72	227	25	be	be	VB
cord-257662-viy65y72	227	26	precursors	precursor	NNS
cord-257662-viy65y72	227	27	of	of	IN
cord-257662-viy65y72	227	28	M2	m2	JJ
cord-257662-viy65y72	227	29	macrophages	macrophage	NNS
cord-257662-viy65y72	227	30	,	,	,
cord-257662-viy65y72	227	31	when	when	WRB
cord-257662-viy65y72	227	32	compared	compare	VBN
cord-257662-viy65y72	227	33	to	to	IN
cord-257662-viy65y72	227	34	seronegative	seronegative	JJ
cord-257662-viy65y72	227	35	or	or	CC
cord-257662-viy65y72	227	36	HIV-1-infected	hiv-1-infecte	VBN
cord-257662-viy65y72	227	37	persons	person	NNS
cord-257662-viy65y72	227	38	with	with	IN
cord-257662-viy65y72	227	39	undetectable	undetectable	JJ
cord-257662-viy65y72	227	40	viral	viral	JJ
cord-257662-viy65y72	227	41	loads	load	NNS
cord-257662-viy65y72	227	42	,	,	,
cord-257662-viy65y72	227	43	and	and	CC
cord-257662-viy65y72	227	44	monocyte	monocyte	NNP
cord-257662-viy65y72	227	45	frequency	frequency	NN
cord-257662-viy65y72	227	46	correlated	correlate	VBD
cord-257662-viy65y72	227	47	positively	positively	RB
cord-257662-viy65y72	227	48	with	with	IN
cord-257662-viy65y72	227	49	HIV-1	HIV-1	NNP
cord-257662-viy65y72	227	50	viremia	viremia	NN
cord-257662-viy65y72	227	51	and	and	CC
cord-257662-viy65y72	227	52	negatively	negatively	RB
cord-257662-viy65y72	227	53	with	with	IN
cord-257662-viy65y72	227	54	CD4	CD4	NNP
cord-257662-viy65y72	227	55	+	+	CC
cord-257662-viy65y72	227	56	T	T	NNP
cord-257662-viy65y72	227	57	cell	cell	NN
cord-257662-viy65y72	227	58	counts	count	NNS
cord-257662-viy65y72	227	59	(	(	-LRB-
cord-257662-viy65y72	227	60	in	in	IN
cord-257662-viy65y72	227	61	patients	patient	NNS
cord-257662-viy65y72	227	62	with	with	IN
cord-257662-viy65y72	227	63	counts	count	NNS
cord-257662-viy65y72	227	64	<	<	XX
cord-257662-viy65y72	227	65	450	450	CD
cord-257662-viy65y72	227	66	cells/µl	cells/µl	CD
cord-257662-viy65y72	227	67	)	)	-RRB-
cord-257662-viy65y72	227	68	(	(	-LRB-
cord-257662-viy65y72	227	69	72	72	CD
cord-257662-viy65y72	227	70	)	)	-RRB-
cord-257662-viy65y72	227	71	.	.	.
cord-257662-viy65y72	228	1	Furthermore	furthermore	RB
cord-257662-viy65y72	228	2	,	,	,
cord-257662-viy65y72	228	3	Qin	Qin	NNP
cord-257662-viy65y72	228	4	and	and	CC
cord-257662-viy65y72	228	5	colleagues	colleague	NNS
cord-257662-viy65y72	228	6	(	(	-LRB-
cord-257662-viy65y72	228	7	73	73	CD
cord-257662-viy65y72	228	8	)	)	-RRB-
cord-257662-viy65y72	228	9	observed	observe	VBD
cord-257662-viy65y72	228	10	elevated	elevated	JJ
cord-257662-viy65y72	228	11	levels	level	NNS
cord-257662-viy65y72	228	12	of	of	IN
cord-257662-viy65y72	228	13	MDSCs	mdsc	NNS
cord-257662-viy65y72	228	14	,	,	,
cord-257662-viy65y72	228	15	defined	define	VBN
cord-257662-viy65y72	228	16	as	as	IN
cord-257662-viy65y72	228	17	HLA	HLA	NNP
cord-257662-viy65y72	228	18	-	-	HYPH
cord-257662-viy65y72	228	19	DR	DR	NNP
cord-257662-viy65y72	228	20	−/low	−/low	CD
cord-257662-viy65y72	228	21	CD11b	CD11b	NNPS
cord-257662-viy65y72	228	22	+	+	CC
cord-257662-viy65y72	228	23	CD33	CD33	NNP
cord-257662-viy65y72	228	24	+	+	CC
cord-257662-viy65y72	228	25	/high	/high	,
cord-257662-viy65y72	228	26	CD14	CD14	NNP
cord-257662-viy65y72	228	27	+	+	CC
cord-257662-viy65y72	228	28	CD15	CD15	NNP
cord-257662-viy65y72	228	29	−	−	NNP
cord-257662-viy65y72	228	30	cells	cell	NNS
cord-257662-viy65y72	228	31	,	,	,
cord-257662-viy65y72	228	32	in	in	IN
cord-257662-viy65y72	228	33	the	the	DT
cord-257662-viy65y72	228	34	peripheral	peripheral	JJ
cord-257662-viy65y72	228	35	blood	blood	NN
cord-257662-viy65y72	228	36	of	of	IN
cord-257662-viy65y72	228	37	HIV-1-seropositive	hiv-1-seropositive	JJ
cord-257662-viy65y72	228	38	subjects	subject	NNS
cord-257662-viy65y72	228	39	compared	compare	VBN
cord-257662-viy65y72	228	40	with	with	IN
cord-257662-viy65y72	228	41	healthy	healthy	JJ
cord-257662-viy65y72	228	42	controls	control	NNS
cord-257662-viy65y72	228	43	,	,	,
cord-257662-viy65y72	228	44	and	and	CC
cord-257662-viy65y72	228	45	these	these	DT
cord-257662-viy65y72	228	46	MDSCs	mdsc	NNS
cord-257662-viy65y72	228	47	suppressed	suppress	VBD
cord-257662-viy65y72	228	48	T	t	NN
cord-257662-viy65y72	228	49	cell	cell	NN
cord-257662-viy65y72	228	50	responses	response	NNS
cord-257662-viy65y72	228	51	in	in	IN
cord-257662-viy65y72	228	52	an	an	DT
cord-257662-viy65y72	228	53	Arg1-dependent	arg1-dependent	CD
cord-257662-viy65y72	228	54	manner	manner	NN
cord-257662-viy65y72	228	55	.	.	.
cord-257662-viy65y72	229	1	Moreover	moreover	RB
cord-257662-viy65y72	229	2	,	,	,
cord-257662-viy65y72	229	3	PBMCs	pbmc	NNS
cord-257662-viy65y72	229	4	from	from	IN
cord-257662-viy65y72	229	5	HIVseropositive	hivseropositive	JJ
cord-257662-viy65y72	229	6	patients	patient	NNS
cord-257662-viy65y72	229	7	exhibited	exhibit	VBD
cord-257662-viy65y72	229	8	increased	increase	VBN
cord-257662-viy65y72	229	9	levels	level	NNS
cord-257662-viy65y72	229	10	of	of	IN
cord-257662-viy65y72	229	11	arginase	arginase	NN
cord-257662-viy65y72	229	12	activity	activity	NN
cord-257662-viy65y72	229	13	(	(	-LRB-
cord-257662-viy65y72	229	14	73	73	CD
cord-257662-viy65y72	229	15	)	)	-RRB-
cord-257662-viy65y72	229	16	.	.	.
cord-257662-viy65y72	230	1	Cloke	cloke	NN
cord-257662-viy65y72	230	2	and	and	CC
cord-257662-viy65y72	230	3	colleagues	colleague	NNS
cord-257662-viy65y72	230	4	(	(	-LRB-
cord-257662-viy65y72	230	5	74	74	CD
cord-257662-viy65y72	230	6	)	)	-RRB-
cord-257662-viy65y72	230	7	found	find	VBD
cord-257662-viy65y72	230	8	that	that	IN
cord-257662-viy65y72	230	9	increased	increase	VBN
cord-257662-viy65y72	230	10	arginase	arginase	NN
cord-257662-viy65y72	230	11	activity	activity	NN
cord-257662-viy65y72	230	12	correlated	correlate	VBN
cord-257662-viy65y72	230	13	with	with	IN
cord-257662-viy65y72	230	14	lower	low	JJR
cord-257662-viy65y72	230	15	CD4	CD4	NNP
cord-257662-viy65y72	230	16	+	+	CC
cord-257662-viy65y72	230	17	T	t	NN
cord-257662-viy65y72	230	18	cell	cell	NN
cord-257662-viy65y72	230	19	counts	count	VBZ
cord-257662-viy65y72	230	20	,	,	,
cord-257662-viy65y72	230	21	and	and	CC
cord-257662-viy65y72	230	22	this	this	DT
cord-257662-viy65y72	230	23	association	association	NN
cord-257662-viy65y72	230	24	was	be	VBD
cord-257662-viy65y72	230	25	abrogated	abrogate	VBN
cord-257662-viy65y72	230	26	following	follow	VBG
cord-257662-viy65y72	230	27	antiretroviral	antiretroviral	JJ
cord-257662-viy65y72	230	28	treatment	treatment	NN
cord-257662-viy65y72	230	29	(	(	-LRB-
cord-257662-viy65y72	230	30	75	75	CD
cord-257662-viy65y72	230	31	)	)	-RRB-
cord-257662-viy65y72	230	32	.	.	.
cord-257662-viy65y72	231	1	Additionally	additionally	RB
cord-257662-viy65y72	231	2	,	,	,
cord-257662-viy65y72	231	3	exposure	exposure	NN
cord-257662-viy65y72	231	4	of	of	IN
cord-257662-viy65y72	231	5	PBMCs	pbmc	NNS
cord-257662-viy65y72	231	6	to	to	IN
cord-257662-viy65y72	232	1	HIV	HIV	NNP
cord-257662-viy65y72	232	2	gp120	gp120	NNP
cord-257662-viy65y72	232	3	expanded	expand	VBD
cord-257662-viy65y72	232	4	T	T	NNP
cord-257662-viy65y72	232	5	cellsuppressive	cellsuppressive	NNP
cord-257662-viy65y72	232	6	MDSCs	mdsc	VBZ
cord-257662-viy65y72	232	7	in	in	IN
cord-257662-viy65y72	232	8	vitro	vitro	FW
cord-257662-viy65y72	232	9	(	(	-LRB-
cord-257662-viy65y72	232	10	76	76	CD
cord-257662-viy65y72	232	11	)	)	-RRB-
cord-257662-viy65y72	232	12	.	.	.
cord-257662-viy65y72	233	1	These	these	DT
cord-257662-viy65y72	233	2	data	datum	NNS
cord-257662-viy65y72	233	3	point	point	NN
cord-257662-viy65y72	233	4	to	to	IN
cord-257662-viy65y72	233	5	a	a	DT
cord-257662-viy65y72	233	6	direct	direct	JJ
cord-257662-viy65y72	233	7	role	role	NN
cord-257662-viy65y72	233	8	for	for	IN
cord-257662-viy65y72	233	9	arginase	arginase	NN
cord-257662-viy65y72	233	10	-	-	HYPH
cord-257662-viy65y72	233	11	expressing	express	VBG
cord-257662-viy65y72	233	12	MDSC	MDSC	NNP
cord-257662-viy65y72	233	13	-	-	HYPH
cord-257662-viy65y72	233	14	like	like	JJ
cord-257662-viy65y72	233	15	cells	cell	NNS
cord-257662-viy65y72	233	16	in	in	IN
cord-257662-viy65y72	233	17	the	the	DT
cord-257662-viy65y72	233	18	suppression	suppression	NN
cord-257662-viy65y72	233	19	of	of	IN
cord-257662-viy65y72	233	20	anti	anti	JJ
cord-257662-viy65y72	233	21	-	-	JJ
cord-257662-viy65y72	233	22	HIV	HIV	NNP
cord-257662-viy65y72	233	23	T	T	NNP
cord-257662-viy65y72	233	24	cell	cell	NN
cord-257662-viy65y72	233	25	responses	response	NNS
cord-257662-viy65y72	233	26	.	.	.
cord-257662-viy65y72	234	1	Consistent	consistent	JJ
cord-257662-viy65y72	234	2	with	with	IN
cord-257662-viy65y72	234	3	that	that	DT
cord-257662-viy65y72	234	4	,	,	,
cord-257662-viy65y72	234	5	individuals	individual	NNS
cord-257662-viy65y72	234	6	co	co	VBD
cord-257662-viy65y72	234	7	-	-	VBN
cord-257662-viy65y72	234	8	infected	infect	VBN
cord-257662-viy65y72	234	9	with	with	IN
cord-257662-viy65y72	234	10	HIV	HIV	NNP
cord-257662-viy65y72	234	11	and	and	CC
cord-257662-viy65y72	234	12	Leishmania	Leishmania	NNP
cord-257662-viy65y72	234	13	parasites	parasite	NNS
cord-257662-viy65y72	234	14	had	have	VBD
cord-257662-viy65y72	234	15	increased	increase	VBN
cord-257662-viy65y72	234	16	arginase	arginase	NN
cord-257662-viy65y72	234	17	activity	activity	NN
cord-257662-viy65y72	234	18	in	in	IN
cord-257662-viy65y72	234	19	PBMCs	pbmc	NNS
cord-257662-viy65y72	234	20	and	and	CC
cord-257662-viy65y72	234	21	plasma	plasma	NN
cord-257662-viy65y72	234	22	compared	compare	VBN
cord-257662-viy65y72	234	23	with	with	IN
cord-257662-viy65y72	234	24	Leishmania	Leishmania	NNP
cord-257662-viy65y72	234	25	-	-	HYPH
cord-257662-viy65y72	234	26	only	only	RB
cord-257662-viy65y72	234	27	infected	infect	VBN
cord-257662-viy65y72	234	28	individuals	individual	NNS
cord-257662-viy65y72	234	29	,	,	,
cord-257662-viy65y72	234	30	even	even	RB
cord-257662-viy65y72	234	31	though	though	IN
cord-257662-viy65y72	234	32	Leishmania	Leishmania	NNP
cord-257662-viy65y72	234	33	infection	infection	NN
cord-257662-viy65y72	234	34	alone	alone	RB
cord-257662-viy65y72	234	35	results	result	VBZ
cord-257662-viy65y72	234	36	in	in	IN
cord-257662-viy65y72	234	37	increased	increase	VBN
cord-257662-viy65y72	234	38	arginase	arginase	NN
cord-257662-viy65y72	234	39	activity	activity	NN
cord-257662-viy65y72	234	40	(	(	-LRB-
cord-257662-viy65y72	234	41	77	77	CD
cord-257662-viy65y72	234	42	)	)	-RRB-
cord-257662-viy65y72	234	43	.	.	.
cord-257662-viy65y72	235	1	In	in	IN
cord-257662-viy65y72	235	2	addition	addition	NN
cord-257662-viy65y72	235	3	,	,	,
cord-257662-viy65y72	235	4	the	the	DT
cord-257662-viy65y72	235	5	parasite	parasite	NN
cord-257662-viy65y72	235	6	load	load	NN
cord-257662-viy65y72	235	7	in	in	IN
cord-257662-viy65y72	235	8	the	the	DT
cord-257662-viy65y72	235	9	spleen	spleen	NN
cord-257662-viy65y72	235	10	was	be	VBD
cord-257662-viy65y72	235	11	significantly	significantly	RB
cord-257662-viy65y72	235	12	higher	high	JJR
cord-257662-viy65y72	235	13	in	in	IN
cord-257662-viy65y72	235	14	co	co	JJ
cord-257662-viy65y72	235	15	-	-	JJ
cord-257662-viy65y72	235	16	infected	infected	JJ
cord-257662-viy65y72	235	17	patients	patient	NNS
cord-257662-viy65y72	235	18	(	(	-LRB-
cord-257662-viy65y72	235	19	77	77	CD
cord-257662-viy65y72	235	20	)	)	-RRB-
cord-257662-viy65y72	235	21	.	.	.
cord-257662-viy65y72	236	1	The	the	DT
cord-257662-viy65y72	236	2	arginase	arginase	NN
cord-257662-viy65y72	236	3	-	-	HYPH
cord-257662-viy65y72	236	4	expressing	express	VBG
cord-257662-viy65y72	236	5	cells	cell	NNS
cord-257662-viy65y72	236	6	were	be	VBD
cord-257662-viy65y72	236	7	identified	identify	VBN
cord-257662-viy65y72	236	8	as	as	IN
cord-257662-viy65y72	236	9	low	low	JJ
cord-257662-viy65y72	236	10	-	-	HYPH
cord-257662-viy65y72	236	11	density	density	NN
cord-257662-viy65y72	236	12	granulocytes	granulocyte	NNS
cord-257662-viy65y72	236	13	(	(	-LRB-
cord-257662-viy65y72	236	14	77	77	CD
cord-257662-viy65y72	236	15	)	)	-RRB-
cord-257662-viy65y72	236	16	.	.	.
cord-257662-viy65y72	237	1	These	these	DT
cord-257662-viy65y72	237	2	results	result	NNS
cord-257662-viy65y72	237	3	suggest	suggest	VBP
cord-257662-viy65y72	237	4	that	that	IN
cord-257662-viy65y72	237	5	increased	increase	VBN
cord-257662-viy65y72	237	6	arginase	arginase	NNP
cord-257662-viy65y72	237	7	might	may	MD
cord-257662-viy65y72	237	8	contribute	contribute	VB
cord-257662-viy65y72	237	9	to	to	IN
cord-257662-viy65y72	237	10	the	the	DT
cord-257662-viy65y72	237	11	poor	poor	JJ
cord-257662-viy65y72	237	12	immune	immune	JJ
cord-257662-viy65y72	237	13	responses	response	NNS
cord-257662-viy65y72	237	14	and	and	CC
cord-257662-viy65y72	237	15	disease	disease	NN
cord-257662-viy65y72	237	16	outcome	outcome	NN
cord-257662-viy65y72	237	17	characteristic	characteristic	NN
cord-257662-viy65y72	237	18	of	of	IN
cord-257662-viy65y72	237	19	patients	patient	NNS
cord-257662-viy65y72	237	20	with	with	IN
cord-257662-viy65y72	237	21	Leishmania	Leishmania	NNP
cord-257662-viy65y72	237	22	and	and	CC
cord-257662-viy65y72	237	23	HIV	HIV	NNP
cord-257662-viy65y72	237	24	co	co	NN
cord-257662-viy65y72	237	25	-	-	NN
cord-257662-viy65y72	237	26	infection	infection	NN
cord-257662-viy65y72	237	27	.	.	.
cord-257662-viy65y72	238	1	Hepatitis	Hepatitis	NNP
cord-257662-viy65y72	238	2	B	B	NNP
cord-257662-viy65y72	238	3	virus	virus	NN
cord-257662-viy65y72	238	4	(	(	-LRB-
cord-257662-viy65y72	238	5	HBV	HBV	NNP
cord-257662-viy65y72	238	6	)	)	-RRB-
cord-257662-viy65y72	238	7	infection	infection	NN
cord-257662-viy65y72	238	8	is	be	VBZ
cord-257662-viy65y72	238	9	another	another	DT
cord-257662-viy65y72	238	10	common	common	JJ
cord-257662-viy65y72	238	11	chronic	chronic	JJ
cord-257662-viy65y72	238	12	viral	viral	JJ
cord-257662-viy65y72	238	13	infection	infection	NN
cord-257662-viy65y72	238	14	,	,	,
cord-257662-viy65y72	238	15	with	with	IN
cord-257662-viy65y72	238	16	estimates	estimate	NNS
cord-257662-viy65y72	238	17	as	as	RB
cord-257662-viy65y72	238	18	high	high	JJ
cord-257662-viy65y72	238	19	as	as	IN
cord-257662-viy65y72	238	20	350	350	CD
cord-257662-viy65y72	238	21	million	million	CD
cord-257662-viy65y72	238	22	chronically	chronically	RB
cord-257662-viy65y72	238	23	infected	infect	VBN
cord-257662-viy65y72	238	24	humans	human	NNS
cord-257662-viy65y72	238	25	(	(	-LRB-
cord-257662-viy65y72	238	26	102	102	CD
cord-257662-viy65y72	238	27	)	)	-RRB-
cord-257662-viy65y72	238	28	.	.	.
cord-257662-viy65y72	239	1	Bility	bility	NN
cord-257662-viy65y72	239	2	and	and	CC
cord-257662-viy65y72	239	3	colleagues	colleague	NNS
cord-257662-viy65y72	239	4	(	(	-LRB-
cord-257662-viy65y72	239	5	78	78	CD
cord-257662-viy65y72	239	6	)	)	-RRB-
cord-257662-viy65y72	239	7	recently	recently	RB
cord-257662-viy65y72	239	8	developed	develop	VBD
cord-257662-viy65y72	239	9	a	a	DT
cord-257662-viy65y72	239	10	humanized	humanized	JJ
cord-257662-viy65y72	239	11	mouse	mouse	NN
cord-257662-viy65y72	239	12	model	model	NN
cord-257662-viy65y72	239	13	with	with	IN
cord-257662-viy65y72	239	14	both	both	CC
cord-257662-viy65y72	239	15	a	a	DT
cord-257662-viy65y72	239	16	human	human	JJ
cord-257662-viy65y72	239	17	immune	immune	NN
cord-257662-viy65y72	239	18	system	system	NN
cord-257662-viy65y72	239	19	and	and	CC
cord-257662-viy65y72	239	20	human	human	JJ
cord-257662-viy65y72	239	21	liver	liver	NN
cord-257662-viy65y72	239	22	cells	cell	NNS
cord-257662-viy65y72	239	23	,	,	,
cord-257662-viy65y72	239	24	named	name	VBD
cord-257662-viy65y72	239	25	the	the	DT
cord-257662-viy65y72	239	26	A2	A2	NNP
cord-257662-viy65y72	239	27	/	/	SYM
cord-257662-viy65y72	239	28	NSG	NSG	NNP
cord-257662-viy65y72	239	29	-	-	HYPH
cord-257662-viy65y72	239	30	hu	hu	NNP
cord-257662-viy65y72	239	31	HSC	HSC	NNP
cord-257662-viy65y72	239	32	/	/	SYM
cord-257662-viy65y72	239	33	Hep	Hep	NNP
cord-257662-viy65y72	239	34	humanized	humanize	VBN
cord-257662-viy65y72	239	35	mouse	mouse	NN
cord-257662-viy65y72	239	36	model	model	NN
cord-257662-viy65y72	239	37	,	,	,
cord-257662-viy65y72	239	38	to	to	TO
cord-257662-viy65y72	239	39	study	study	VB
cord-257662-viy65y72	239	40	the	the	DT
cord-257662-viy65y72	239	41	pathogenesis	pathogenesis	NN
cord-257662-viy65y72	239	42	of	of	IN
cord-257662-viy65y72	239	43	HBV	HBV	NNP
cord-257662-viy65y72	239	44	infection	infection	NN
cord-257662-viy65y72	239	45	.	.	.
cord-257662-viy65y72	240	1	Following	follow	VBG
cord-257662-viy65y72	240	2	HBV	HBV	NNP
cord-257662-viy65y72	240	3	infection	infection	NN
cord-257662-viy65y72	240	4	,	,	,
cord-257662-viy65y72	240	5	the	the	DT
cord-257662-viy65y72	240	6	mice	mouse	NNS
cord-257662-viy65y72	240	7	developed	develop	VBD
cord-257662-viy65y72	240	8	persistent	persistent	JJ
cord-257662-viy65y72	240	9	HBV	HBV	NNP
cord-257662-viy65y72	240	10	infection	infection	NN
cord-257662-viy65y72	240	11	as	as	RB
cord-257662-viy65y72	240	12	well	well	RB
cord-257662-viy65y72	240	13	as	as	IN
cord-257662-viy65y72	240	14	chronic	chronic	JJ
cord-257662-viy65y72	240	15	hepatitis	hepatitis	NN
cord-257662-viy65y72	240	16	and	and	CC
cord-257662-viy65y72	240	17	liver	liver	NN
cord-257662-viy65y72	240	18	fibrosis	fibrosis	NN
cord-257662-viy65y72	240	19	(	(	-LRB-
cord-257662-viy65y72	240	20	78	78	CD
cord-257662-viy65y72	240	21	)	)	-RRB-
cord-257662-viy65y72	240	22	.	.	.
cord-257662-viy65y72	241	1	The	the	DT
cord-257662-viy65y72	241	2	liver	liver	NN
cord-257662-viy65y72	241	3	disease	disease	NN
cord-257662-viy65y72	241	4	was	be	VBD
cord-257662-viy65y72	241	5	associated	associate	VBN
cord-257662-viy65y72	241	6	with	with	IN
cord-257662-viy65y72	241	7	a	a	DT
cord-257662-viy65y72	241	8	high	high	JJ
cord-257662-viy65y72	241	9	level	level	NN
cord-257662-viy65y72	241	10	of	of	IN
cord-257662-viy65y72	241	11	infiltrating	infiltrate	VBG
cord-257662-viy65y72	241	12	human	human	JJ
cord-257662-viy65y72	241	13	macrophages	macrophage	NNS
cord-257662-viy65y72	241	14	with	with	IN
cord-257662-viy65y72	241	15	a	a	DT
cord-257662-viy65y72	241	16	M2-like	M2-like	NNS
cord-257662-viy65y72	241	17	activation	activation	NN
cord-257662-viy65y72	241	18	phenotype	phenotype	NN
cord-257662-viy65y72	241	19	(	(	-LRB-
cord-257662-viy65y72	241	20	78	78	CD
cord-257662-viy65y72	241	21	)	)	-RRB-
cord-257662-viy65y72	241	22	.	.	.
cord-257662-viy65y72	242	1	Similarly	similarly	RB
cord-257662-viy65y72	242	2	,	,	,
cord-257662-viy65y72	242	3	M2-like	M2-like	NNP
cord-257662-viy65y72	242	4	macrophage	macrophage	NN
cord-257662-viy65y72	242	5	accumulation	accumulation	NN
cord-257662-viy65y72	242	6	was	be	VBD
cord-257662-viy65y72	242	7	seen	see	VBN
cord-257662-viy65y72	242	8	in	in	IN
cord-257662-viy65y72	242	9	chronic	chronic	JJ
cord-257662-viy65y72	242	10	HBV	HBV	NNP
cord-257662-viy65y72	242	11	-	-	HYPH
cord-257662-viy65y72	242	12	infected	infect	VBN
cord-257662-viy65y72	242	13	patients	patient	NNS
cord-257662-viy65y72	242	14	,	,	,
cord-257662-viy65y72	242	15	and	and	CC
cord-257662-viy65y72	242	16	M2-like	M2-like	NNP
cord-257662-viy65y72	242	17	macrophage	macrophage	NN
cord-257662-viy65y72	242	18	induction	induction	NN
cord-257662-viy65y72	242	19	in	in	IN
cord-257662-viy65y72	242	20	the	the	DT
cord-257662-viy65y72	242	21	liver	liver	NN
cord-257662-viy65y72	242	22	was	be	VBD
cord-257662-viy65y72	242	23	associated	associate	VBN
cord-257662-viy65y72	242	24	with	with	IN
cord-257662-viy65y72	242	25	accelerated	accelerated	JJ
cord-257662-viy65y72	242	26	liver	liver	NN
cord-257662-viy65y72	242	27	fibrosis	fibrosis	NN
cord-257662-viy65y72	242	28	and	and	CC
cord-257662-viy65y72	242	29	necrosis	necrosis	NN
cord-257662-viy65y72	242	30	in	in	IN
cord-257662-viy65y72	242	31	patients	patient	NNS
cord-257662-viy65y72	242	32	with	with	IN
cord-257662-viy65y72	242	33	acute	acute	JJ
cord-257662-viy65y72	242	34	HBV	HBV	NNP
cord-257662-viy65y72	242	35	-	-	HYPH
cord-257662-viy65y72	242	36	induced	induce	VBN
cord-257662-viy65y72	242	37	liver	liver	NN
cord-257662-viy65y72	242	38	failure	failure	NN
cord-257662-viy65y72	242	39	(	(	-LRB-
cord-257662-viy65y72	242	40	78	78	CD
cord-257662-viy65y72	242	41	)	)	-RRB-
cord-257662-viy65y72	242	42	,	,	,
cord-257662-viy65y72	242	43	suggesting	suggest	VBG
cord-257662-viy65y72	242	44	a	a	DT
cord-257662-viy65y72	242	45	role	role	NN
cord-257662-viy65y72	242	46	for	for	IN
cord-257662-viy65y72	242	47	M2	M2	NNP
cord-257662-viy65y72	242	48	macrophages	macrophage	NNS
cord-257662-viy65y72	242	49	in	in	IN
cord-257662-viy65y72	242	50	persistent	persistent	JJ
cord-257662-viy65y72	242	51	HBV	HBV	NNP
cord-257662-viy65y72	242	52	infection	infection	NN
cord-257662-viy65y72	242	53	.	.	.
cord-257662-viy65y72	243	1	Additionally	additionally	RB
cord-257662-viy65y72	243	2	,	,	,
cord-257662-viy65y72	243	3	patients	patient	NNS
cord-257662-viy65y72	243	4	with	with	IN
cord-257662-viy65y72	243	5	acute	acute	JJ
cord-257662-viy65y72	243	6	HBV	HBV	NNP
cord-257662-viy65y72	243	7	infection	infection	NN
cord-257662-viy65y72	243	8	had	have	VBD
cord-257662-viy65y72	243	9	increased	increase	VBN
cord-257662-viy65y72	243	10	serum	serum	NN
cord-257662-viy65y72	243	11	levels	level	NNS
cord-257662-viy65y72	243	12	of	of	IN
cord-257662-viy65y72	243	13	arginase	arginase	NN
cord-257662-viy65y72	243	14	,	,	,
cord-257662-viy65y72	243	15	and	and	CC
cord-257662-viy65y72	243	16	this	this	DT
cord-257662-viy65y72	243	17	serum	serum	NN
cord-257662-viy65y72	243	18	inhibited	inhibit	VBD
cord-257662-viy65y72	243	19	IFN	IFN	NNP
cord-257662-viy65y72	243	20	-	-	HYPH
cord-257662-viy65y72	243	21	γ	γ	NN
cord-257662-viy65y72	243	22	production	production	NN
cord-257662-viy65y72	243	23	by	by	IN
cord-257662-viy65y72	243	24	CD8	CD8	NNP
cord-257662-viy65y72	243	25	+	+	CC
cord-257662-viy65y72	243	26	T	T	NNP
cord-257662-viy65y72	243	27	cells	cell	NNS
cord-257662-viy65y72	243	28	(	(	-LRB-
cord-257662-viy65y72	243	29	79	79	CD
cord-257662-viy65y72	243	30	)	)	-RRB-
cord-257662-viy65y72	243	31	.	.	.
cord-257662-viy65y72	244	1	Das	Das	NNP
cord-257662-viy65y72	244	2	et	et	FW
cord-257662-viy65y72	244	3	al	al	NNP
cord-257662-viy65y72	244	4	.	.	.
cord-257662-viy65y72	245	1	(	(	-LRB-
cord-257662-viy65y72	245	2	80	80	CD
cord-257662-viy65y72	245	3	)	)	-RRB-
cord-257662-viy65y72	245	4	also	also	RB
cord-257662-viy65y72	245	5	found	find	VBD
cord-257662-viy65y72	245	6	decreased	decrease	VBN
cord-257662-viy65y72	245	7	l	l	NN
cord-257662-viy65y72	245	8	-	-	HYPH
cord-257662-viy65y72	245	9	arginine	arginine	NN
cord-257662-viy65y72	245	10	levels	level	NNS
cord-257662-viy65y72	245	11	in	in	IN
cord-257662-viy65y72	245	12	the	the	DT
cord-257662-viy65y72	245	13	circulation	circulation	NN
cord-257662-viy65y72	245	14	of	of	IN
cord-257662-viy65y72	245	15	chronic	chronic	JJ
cord-257662-viy65y72	245	16	HBV	HBV	NNP
cord-257662-viy65y72	245	17	patients	patient	NNS
cord-257662-viy65y72	245	18	with	with	IN
cord-257662-viy65y72	245	19	marked	marked	JJ
cord-257662-viy65y72	245	20	liver	liver	NN
cord-257662-viy65y72	245	21	inflammation	inflammation	NN
cord-257662-viy65y72	245	22	(	(	-LRB-
cord-257662-viy65y72	245	23	>	>	NFP
cord-257662-viy65y72	245	24	100	100	CD
cord-257662-viy65y72	245	25	ALT	alt	NN
cord-257662-viy65y72	245	26	)	)	-RRB-
cord-257662-viy65y72	245	27	and	and	CC
cord-257662-viy65y72	245	28	increased	increase	VBN
cord-257662-viy65y72	245	29	arginase	arginase	NN
cord-257662-viy65y72	245	30	activity	activity	NN
cord-257662-viy65y72	245	31	in	in	IN
cord-257662-viy65y72	245	32	liver	liver	NN
cord-257662-viy65y72	245	33	extracts	extract	NNS
cord-257662-viy65y72	245	34	taken	take	VBN
cord-257662-viy65y72	245	35	directly	directly	RB
cord-257662-viy65y72	245	36	ex	ex	FW
cord-257662-viy65y72	245	37	vivo	vivo	NN
cord-257662-viy65y72	245	38	from	from	IN
cord-257662-viy65y72	245	39	patients	patient	NNS
cord-257662-viy65y72	245	40	with	with	IN
cord-257662-viy65y72	245	41	chronic	chronic	JJ
cord-257662-viy65y72	245	42	HBV	HBV	NNP
cord-257662-viy65y72	245	43	compared	compare	VBN
cord-257662-viy65y72	245	44	with	with	IN
cord-257662-viy65y72	245	45	those	those	DT
cord-257662-viy65y72	245	46	from	from	IN
cord-257662-viy65y72	245	47	patients	patient	NNS
cord-257662-viy65y72	245	48	with	with	IN
cord-257662-viy65y72	245	49	other	other	JJ
cord-257662-viy65y72	245	50	types	type	NNS
cord-257662-viy65y72	245	51	of	of	IN
cord-257662-viy65y72	245	52	liver	liver	NN
cord-257662-viy65y72	245	53	pathology	pathology	NN
cord-257662-viy65y72	245	54	(	(	-LRB-
cord-257662-viy65y72	245	55	80	80	CD
cord-257662-viy65y72	245	56	)	)	-RRB-
cord-257662-viy65y72	245	57	.	.	.
cord-257662-viy65y72	246	1	They	-PRON-	PRP
cord-257662-viy65y72	246	2	further	further	RB
cord-257662-viy65y72	246	3	showed	show	VBD
cord-257662-viy65y72	246	4	that	that	IN
cord-257662-viy65y72	246	5	CD8	CD8	NNP
cord-257662-viy65y72	246	6	+	+	CC
cord-257662-viy65y72	246	7	T	T	NNP
cord-257662-viy65y72	246	8	cells	cell	NNS
cord-257662-viy65y72	246	9	from	from	IN
cord-257662-viy65y72	246	10	chronic	chronic	JJ
cord-257662-viy65y72	246	11	HBV	HBV	NNP
cord-257662-viy65y72	246	12	patients	patient	NNS
cord-257662-viy65y72	246	13	,	,	,
cord-257662-viy65y72	246	14	regardless	regardless	RB
cord-257662-viy65y72	246	15	of	of	IN
cord-257662-viy65y72	246	16	their	-PRON-	PRP$
cord-257662-viy65y72	246	17	antigen	antigen	NN
cord-257662-viy65y72	246	18	specificity	specificity	NN
cord-257662-viy65y72	246	19	,	,	,
cord-257662-viy65y72	246	20	exhibited	exhibit	VBD
cord-257662-viy65y72	246	21	less	less	JJR
cord-257662-viy65y72	246	22	IL-2	il-2	NN
cord-257662-viy65y72	246	23	but	but	CC
cord-257662-viy65y72	246	24	not	not	RB
cord-257662-viy65y72	246	25	IFN	IFN	NNP
cord-257662-viy65y72	246	26	-	-	HYPH
cord-257662-viy65y72	246	27	γ	γ	NNP
cord-257662-viy65y72	246	28	or	or	CC
cord-257662-viy65y72	246	29	TNF	TNF	NNP
cord-257662-viy65y72	246	30	-	-	HYPH
cord-257662-viy65y72	246	31	α	α	NN
cord-257662-viy65y72	246	32	production	production	NN
cord-257662-viy65y72	246	33	and	and	CC
cord-257662-viy65y72	246	34	impaired	impair	VBN
cord-257662-viy65y72	246	35	proliferation	proliferation	NN
cord-257662-viy65y72	246	36	following	follow	VBG
cord-257662-viy65y72	246	37	TCR	TCR	NNP
cord-257662-viy65y72	246	38	-	-	HYPH
cord-257662-viy65y72	246	39	dependent	dependent	JJ
cord-257662-viy65y72	246	40	stimulation	stimulation	NN
cord-257662-viy65y72	246	41	,	,	,
cord-257662-viy65y72	246	42	indicating	indicate	VBG
cord-257662-viy65y72	246	43	an	an	DT
cord-257662-viy65y72	246	44	aberrant	aberrant	JJ
cord-257662-viy65y72	246	45	antiviral	antiviral	JJ
cord-257662-viy65y72	246	46	T	t	NN
cord-257662-viy65y72	246	47	cell	cell	NN
cord-257662-viy65y72	246	48	response	response	NN
cord-257662-viy65y72	246	49	in	in	IN
cord-257662-viy65y72	246	50	chronic	chronic	JJ
cord-257662-viy65y72	246	51	HBV	HBV	NNP
cord-257662-viy65y72	246	52	infection	infection	NN
cord-257662-viy65y72	246	53	(	(	-LRB-
cord-257662-viy65y72	246	54	80	80	CD
cord-257662-viy65y72	246	55	)	)	-RRB-
cord-257662-viy65y72	246	56	.	.	.
cord-257662-viy65y72	247	1	In	in	IN
cord-257662-viy65y72	247	2	the	the	DT
cord-257662-viy65y72	247	3	A2	A2	NNP
cord-257662-viy65y72	247	4	/	/	SYM
cord-257662-viy65y72	247	5	NSG	NSG	NNP
cord-257662-viy65y72	247	6	-	-	HYPH
cord-257662-viy65y72	247	7	hu	hu	NNP
cord-257662-viy65y72	247	8	HSC	HSC	NNP
cord-257662-viy65y72	247	9	/	/	SYM
cord-257662-viy65y72	247	10	Hep	Hep	NNP
cord-257662-viy65y72	247	11	humanized	humanize	VBN
cord-257662-viy65y72	247	12	mouse	mouse	NN
cord-257662-viy65y72	247	13	model	model	NN
cord-257662-viy65y72	247	14	,	,	,
cord-257662-viy65y72	247	15	HBV	HBV	NNP
cord-257662-viy65y72	247	16	-	-	HYPH
cord-257662-viy65y72	247	17	infected	infect	VBN
cord-257662-viy65y72	247	18	mice	mouse	NNS
cord-257662-viy65y72	247	19	had	have	VBD
cord-257662-viy65y72	247	20	impaired	impair	VBN
cord-257662-viy65y72	247	21	liver	liver	NN
cord-257662-viy65y72	247	22	T	t	NN
cord-257662-viy65y72	247	23	cell	cell	NN
cord-257662-viy65y72	247	24	responses	response	NNS
cord-257662-viy65y72	247	25	,	,	,
cord-257662-viy65y72	247	26	and	and	CC
cord-257662-viy65y72	247	27	M2	m2	JJ
cord-257662-viy65y72	247	28	macrophages	macrophage	NNS
cord-257662-viy65y72	247	29	were	be	VBD
cord-257662-viy65y72	247	30	associated	associate	VBN
cord-257662-viy65y72	247	31	with	with	IN
cord-257662-viy65y72	247	32	T	T	NNP
cord-257662-viy65y72	247	33	cells	cell	NNS
cord-257662-viy65y72	247	34	in	in	IN
cord-257662-viy65y72	247	35	the	the	DT
cord-257662-viy65y72	247	36	liver	liver	NN
cord-257662-viy65y72	247	37	(	(	-LRB-
cord-257662-viy65y72	247	38	78	78	CD
cord-257662-viy65y72	247	39	)	)	-RRB-
cord-257662-viy65y72	247	40	.	.	.
cord-257662-viy65y72	248	1	Expression	expression	NN
cord-257662-viy65y72	248	2	of	of	IN
cord-257662-viy65y72	248	3	the	the	DT
cord-257662-viy65y72	248	4	TCR	TCR	NNP
cord-257662-viy65y72	248	5	signaling	signaling	NN
cord-257662-viy65y72	248	6	molecule	molecule	NN
cord-257662-viy65y72	249	1	CD3ζ	CD3ζ	NNP
cord-257662-viy65y72	249	2	was	be	VBD
cord-257662-viy65y72	249	3	reduced	reduce	VBN
cord-257662-viy65y72	249	4	in	in	IN
cord-257662-viy65y72	249	5	both	both	DT
cord-257662-viy65y72	249	6	peripheral	peripheral	JJ
cord-257662-viy65y72	249	7	and	and	CC
cord-257662-viy65y72	249	8	intrahepatic	intrahepatic	JJ
cord-257662-viy65y72	249	9	CD8	CD8	NNP
cord-257662-viy65y72	249	10	+	+	CC
cord-257662-viy65y72	249	11	T	T	NNP
cord-257662-viy65y72	249	12	cells	cell	NNS
cord-257662-viy65y72	249	13	from	from	IN
cord-257662-viy65y72	249	14	chronic	chronic	JJ
cord-257662-viy65y72	249	15	HBV	HBV	NNP
cord-257662-viy65y72	249	16	patients	patient	NNS
cord-257662-viy65y72	249	17	;	;	:
cord-257662-viy65y72	249	18	similarly	similarly	RB
cord-257662-viy65y72	249	19	,	,	,
cord-257662-viy65y72	249	20	CD28	CD28	NNP
cord-257662-viy65y72	249	21	was	be	VBD
cord-257662-viy65y72	249	22	also	also	RB
cord-257662-viy65y72	249	23	downregulated	downregulate	VBN
cord-257662-viy65y72	249	24	on	on	IN
cord-257662-viy65y72	249	25	CD8	CD8	NNP
cord-257662-viy65y72	249	26	+	+	CC
cord-257662-viy65y72	249	27	T	T	NNP
cord-257662-viy65y72	249	28	cells	cell	NNS
cord-257662-viy65y72	249	29	from	from	IN
cord-257662-viy65y72	249	30	high	high	JJ
cord-257662-viy65y72	249	31	viral	viral	JJ
cord-257662-viy65y72	249	32	load	load	NN
cord-257662-viy65y72	249	33	HBV	HBV	NNP
cord-257662-viy65y72	249	34	patients	patient	NNS
cord-257662-viy65y72	249	35	(	(	-LRB-
cord-257662-viy65y72	249	36	80	80	CD
cord-257662-viy65y72	249	37	)	)	-RRB-
cord-257662-viy65y72	249	38	.	.	.
cord-257662-viy65y72	250	1	Downregulation	Downregulation	NNP
cord-257662-viy65y72	250	2	of	of	IN
cord-257662-viy65y72	250	3	the	the	DT
cord-257662-viy65y72	250	4	CD3ζ	CD3ζ	NNP
cord-257662-viy65y72	250	5	molecule	molecule	NN
cord-257662-viy65y72	250	6	has	have	VBZ
cord-257662-viy65y72	250	7	previously	previously	RB
cord-257662-viy65y72	250	8	been	be	VBN
cord-257662-viy65y72	250	9	shown	show	VBN
cord-257662-viy65y72	250	10	to	to	TO
cord-257662-viy65y72	250	11	occur	occur	VB
cord-257662-viy65y72	250	12	in	in	IN
cord-257662-viy65y72	250	13	the	the	DT
cord-257662-viy65y72	250	14	arginine	arginine	NN
cord-257662-viy65y72	250	15	-	-	HYPH
cord-257662-viy65y72	250	16	depleted	deplete	VBN
cord-257662-viy65y72	250	17	tumor	tumor	NN
cord-257662-viy65y72	250	18	microenvironment	microenvironment	NN
cord-257662-viy65y72	250	19	.	.	.
cord-257662-viy65y72	251	1	Consistent	consistent	JJ
cord-257662-viy65y72	251	2	with	with	IN
cord-257662-viy65y72	251	3	this	this	DT
cord-257662-viy65y72	251	4	,	,	,
cord-257662-viy65y72	251	5	in	in	IN
cord-257662-viy65y72	251	6	vitro	vitro	FW
cord-257662-viy65y72	251	7	transfection	transfection	NN
cord-257662-viy65y72	251	8	of	of	IN
cord-257662-viy65y72	251	9	CD3ζ	CD3ζ	NNP
cord-257662-viy65y72	251	10	and	and	CC
cord-257662-viy65y72	251	11	CD28	CD28	NNP
cord-257662-viy65y72	251	12	restored	restore	VBD
cord-257662-viy65y72	251	13	IL-2	IL-2	NNP
cord-257662-viy65y72	251	14	production	production	NN
cord-257662-viy65y72	251	15	and	and	CC
cord-257662-viy65y72	251	16	supplementation	supplementation	NN
cord-257662-viy65y72	251	17	of	of	IN
cord-257662-viy65y72	251	18	l	l	NN
cord-257662-viy65y72	251	19	-	-	HYPH
cord-257662-viy65y72	251	20	arginine	arginine	NN
cord-257662-viy65y72	251	21	partially	partially	RB
cord-257662-viy65y72	251	22	restored	restore	VBD
cord-257662-viy65y72	251	23	CD3ζ	CD3ζ	NNP
cord-257662-viy65y72	251	24	expression	expression	NN
cord-257662-viy65y72	251	25	and	and	CC
cord-257662-viy65y72	251	26	T	t	NN
cord-257662-viy65y72	251	27	cell	cell	NN
cord-257662-viy65y72	251	28	proliferation	proliferation	NN
cord-257662-viy65y72	251	29	(	(	-LRB-
cord-257662-viy65y72	251	30	80	80	CD
cord-257662-viy65y72	251	31	)	)	-RRB-
cord-257662-viy65y72	251	32	.	.	.
cord-257662-viy65y72	252	1	These	these	DT
cord-257662-viy65y72	252	2	data	datum	NNS
cord-257662-viy65y72	252	3	suggest	suggest	VBP
cord-257662-viy65y72	252	4	a	a	DT
cord-257662-viy65y72	252	5	role	role	NN
cord-257662-viy65y72	252	6	www.frontiersin.org	www.frontiersin.org	IN
cord-257662-viy65y72	252	7	for	for	IN
cord-257662-viy65y72	252	8	arginase	arginase	NN
cord-257662-viy65y72	252	9	activity	activity	NN
cord-257662-viy65y72	252	10	and	and	CC
cord-257662-viy65y72	252	11	arginine	arginine	NN
cord-257662-viy65y72	252	12	depletion	depletion	NN
cord-257662-viy65y72	252	13	in	in	IN
cord-257662-viy65y72	252	14	the	the	DT
cord-257662-viy65y72	252	15	impairment	impairment	NN
cord-257662-viy65y72	252	16	of	of	IN
cord-257662-viy65y72	252	17	anti	anti	JJ
cord-257662-viy65y72	252	18	-	-	JJ
cord-257662-viy65y72	252	19	HBV	hbv	JJ
cord-257662-viy65y72	252	20	T	T	NNP
cord-257662-viy65y72	252	21	cells	cell	NNS
cord-257662-viy65y72	252	22	functions	function	NNS
cord-257662-viy65y72	252	23	.	.	.
cord-257662-viy65y72	253	1	In	in	IN
cord-257662-viy65y72	253	2	the	the	DT
cord-257662-viy65y72	253	3	absence	absence	NN
cord-257662-viy65y72	253	4	of	of	IN
cord-257662-viy65y72	253	5	iNKT	inkt	JJ
cord-257662-viy65y72	253	6	cells	cell	NNS
cord-257662-viy65y72	253	7	,	,	,
cord-257662-viy65y72	253	8	influenza	influenza	NN
cord-257662-viy65y72	253	9	A	a	NN
cord-257662-viy65y72	253	10	(	(	-LRB-
cord-257662-viy65y72	253	11	PR/8	PR/8	NNP
cord-257662-viy65y72	253	12	strain	strain	VB
cord-257662-viy65y72	253	13	)	)	-RRB-
cord-257662-viy65y72	253	14	infection	infection	NN
cord-257662-viy65y72	253	15	was	be	VBD
cord-257662-viy65y72	253	16	shown	show	VBN
cord-257662-viy65y72	253	17	to	to	TO
cord-257662-viy65y72	253	18	induce	induce	VB
cord-257662-viy65y72	253	19	the	the	DT
cord-257662-viy65y72	253	20	expansion	expansion	NN
cord-257662-viy65y72	253	21	of	of	IN
cord-257662-viy65y72	253	22	CD11b	CD11b	NNS
cord-257662-viy65y72	253	23	+	+	CC
cord-257662-viy65y72	254	1	GR-1	GR-1	NNP
cord-257662-viy65y72	255	1	+	+	CC
cord-257662-viy65y72	256	1	MDSCs	mdsc	NNS
cord-257662-viy65y72	256	2	in	in	IN
cord-257662-viy65y72	256	3	the	the	DT
cord-257662-viy65y72	256	4	lungs	lung	NNS
cord-257662-viy65y72	256	5	of	of	IN
cord-257662-viy65y72	256	6	mice	mouse	NNS
cord-257662-viy65y72	256	7	,	,	,
cord-257662-viy65y72	256	8	which	which	WDT
cord-257662-viy65y72	256	9	suppressed	suppress	VBD
cord-257662-viy65y72	256	10	influenza	influenza	NN
cord-257662-viy65y72	256	11	-	-	HYPH
cord-257662-viy65y72	256	12	specific	specific	JJ
cord-257662-viy65y72	256	13	T	t	NN
cord-257662-viy65y72	256	14	cell	cell	NN
cord-257662-viy65y72	256	15	and	and	CC
cord-257662-viy65y72	256	16	antibody	antibody	NN
cord-257662-viy65y72	256	17	responses	response	NNS
cord-257662-viy65y72	256	18	through	through	IN
cord-257662-viy65y72	256	19	the	the	DT
cord-257662-viy65y72	256	20	activity	activity	NN
cord-257662-viy65y72	256	21	of	of	IN
cord-257662-viy65y72	256	22	both	both	CC
cord-257662-viy65y72	256	23	arginase	arginase	NN
cord-257662-viy65y72	256	24	and	and	CC
cord-257662-viy65y72	256	25	NOS	NOS	NNP
cord-257662-viy65y72	256	26	,	,	,
cord-257662-viy65y72	256	27	resulting	result	VBG
cord-257662-viy65y72	256	28	in	in	IN
cord-257662-viy65y72	256	29	higher	high	JJR
cord-257662-viy65y72	256	30	viral	viral	JJ
cord-257662-viy65y72	256	31	titers	titer	NNS
cord-257662-viy65y72	256	32	and	and	CC
cord-257662-viy65y72	256	33	increased	increase	VBN
cord-257662-viy65y72	256	34	mortality	mortality	NN
cord-257662-viy65y72	256	35	(	(	-LRB-
cord-257662-viy65y72	256	36	81	81	CD
cord-257662-viy65y72	256	37	)	)	-RRB-
cord-257662-viy65y72	256	38	.	.	.
cord-257662-viy65y72	257	1	Adoptive	adoptive	JJ
cord-257662-viy65y72	257	2	transfer	transfer	NN
cord-257662-viy65y72	257	3	of	of	IN
cord-257662-viy65y72	257	4	iNKT	inkt	JJ
cord-257662-viy65y72	257	5	cells	cell	NNS
cord-257662-viy65y72	257	6	reversed	reverse	VBD
cord-257662-viy65y72	257	7	this	this	DT
cord-257662-viy65y72	257	8	phenotype	phenotype	NN
cord-257662-viy65y72	257	9	;	;	:
cord-257662-viy65y72	257	10	mice	mouse	NNS
cord-257662-viy65y72	257	11	had	have	VBD
cord-257662-viy65y72	257	12	an	an	DT
cord-257662-viy65y72	257	13	increased	increase	VBN
cord-257662-viy65y72	257	14	survival	survival	NN
cord-257662-viy65y72	257	15	rate	rate	NN
cord-257662-viy65y72	257	16	,	,	,
cord-257662-viy65y72	257	17	reduced	reduce	VBN
cord-257662-viy65y72	257	18	viral	viral	JJ
cord-257662-viy65y72	257	19	titers	titer	NNS
cord-257662-viy65y72	257	20	,	,	,
cord-257662-viy65y72	257	21	and	and	CC
cord-257662-viy65y72	257	22	increased	increase	VBD
cord-257662-viy65y72	257	23	virusspecific	virusspecific	JJ
cord-257662-viy65y72	257	24	immune	immune	JJ
cord-257662-viy65y72	257	25	responses	response	NNS
cord-257662-viy65y72	257	26	,	,	,
cord-257662-viy65y72	257	27	suggesting	suggest	VBG
cord-257662-viy65y72	257	28	a	a	DT
cord-257662-viy65y72	257	29	novel	novel	JJ
cord-257662-viy65y72	257	30	immunomodulatory	immunomodulatory	JJ
cord-257662-viy65y72	257	31	role	role	NN
cord-257662-viy65y72	257	32	for	for	IN
cord-257662-viy65y72	257	33	iNKT	inkt	JJ
cord-257662-viy65y72	257	34	cells	cell	NNS
cord-257662-viy65y72	257	35	during	during	IN
cord-257662-viy65y72	257	36	influenza	influenza	NN
cord-257662-viy65y72	257	37	virus	virus	NN
cord-257662-viy65y72	257	38	infection	infection	NN
cord-257662-viy65y72	257	39	(	(	-LRB-
cord-257662-viy65y72	257	40	81	81	CD
cord-257662-viy65y72	257	41	)	)	-RRB-
cord-257662-viy65y72	257	42	.	.	.
cord-257662-viy65y72	258	1	Moreover	moreover	RB
cord-257662-viy65y72	258	2	,	,	,
cord-257662-viy65y72	258	3	these	these	DT
cord-257662-viy65y72	258	4	authors	author	NNS
cord-257662-viy65y72	258	5	identified	identify	VBD
cord-257662-viy65y72	258	6	that	that	IN
cord-257662-viy65y72	258	7	influenza	influenza	NN
cord-257662-viy65y72	258	8	infection	infection	NN
cord-257662-viy65y72	258	9	in	in	IN
cord-257662-viy65y72	258	10	humans	human	NNS
cord-257662-viy65y72	258	11	induced	induce	VBD
cord-257662-viy65y72	258	12	the	the	DT
cord-257662-viy65y72	258	13	expansion	expansion	NN
cord-257662-viy65y72	258	14	of	of	IN
cord-257662-viy65y72	258	15	CD11b	CD11b	NNS
cord-257662-viy65y72	258	16	+	+	CC
cord-257662-viy65y72	258	17	myeloid	myeloid	NN
cord-257662-viy65y72	258	18	cells	cell	NNS
cord-257662-viy65y72	258	19	with	with	IN
cord-257662-viy65y72	258	20	suppressive	suppressive	JJ
cord-257662-viy65y72	258	21	activity	activity	NN
cord-257662-viy65y72	258	22	that	that	WDT
cord-257662-viy65y72	258	23	could	could	MD
cord-257662-viy65y72	258	24	be	be	VB
cord-257662-viy65y72	258	25	reduced	reduce	VBN
cord-257662-viy65y72	258	26	by	by	IN
cord-257662-viy65y72	258	27	iNKT	inkt	JJ
cord-257662-viy65y72	258	28	cell	cell	NN
cord-257662-viy65y72	258	29	activation	activation	NN
cord-257662-viy65y72	258	30	or	or	CC
cord-257662-viy65y72	258	31	the	the	DT
cord-257662-viy65y72	258	32	inhibition	inhibition	NN
cord-257662-viy65y72	258	33	of	of	IN
cord-257662-viy65y72	258	34	arginase	arginase	NN
cord-257662-viy65y72	258	35	and	and	CC
cord-257662-viy65y72	258	36	NOS	NOS	NNP
cord-257662-viy65y72	258	37	activity	activity	NN
cord-257662-viy65y72	258	38	.	.	.
cord-257662-viy65y72	259	1	Similarly	similarly	RB
cord-257662-viy65y72	259	2	,	,	,
cord-257662-viy65y72	259	3	it	-PRON-	PRP
cord-257662-viy65y72	259	4	was	be	VBD
cord-257662-viy65y72	259	5	recently	recently	RB
cord-257662-viy65y72	259	6	shown	show	VBN
cord-257662-viy65y72	259	7	that	that	IN
cord-257662-viy65y72	259	8	highly	highly	RB
cord-257662-viy65y72	259	9	pathogenic	pathogenic	JJ
cord-257662-viy65y72	259	10	H5N1	H5N1	NNP
cord-257662-viy65y72	259	11	and	and	CC
cord-257662-viy65y72	259	12	H1N1	H1N1	NNP
cord-257662-viy65y72	259	13	influenza	influenza	NN
cord-257662-viy65y72	259	14	virus	virus	NN
cord-257662-viy65y72	259	15	infection	infection	NN
cord-257662-viy65y72	259	16	induced	induce	VBD
cord-257662-viy65y72	259	17	the	the	DT
cord-257662-viy65y72	259	18	accumulation	accumulation	NN
cord-257662-viy65y72	259	19	of	of	IN
cord-257662-viy65y72	259	20	CD11b	CD11b	NNS
cord-257662-viy65y72	259	21	+	+	CC
cord-257662-viy65y72	259	22	GR-1	gr-1	NN
cord-257662-viy65y72	260	1	+	+	CC
cord-257662-viy65y72	260	2	cells	cell	NNS
cord-257662-viy65y72	260	3	and	and	CC
cord-257662-viy65y72	260	4	the	the	DT
cord-257662-viy65y72	260	5	expression	expression	NN
cord-257662-viy65y72	260	6	of	of	IN
cord-257662-viy65y72	260	7	Arg1	Arg1	NNP
cord-257662-viy65y72	260	8	in	in	IN
cord-257662-viy65y72	260	9	the	the	DT
cord-257662-viy65y72	260	10	lungs	lung	NNS
cord-257662-viy65y72	260	11	(	(	-LRB-
cord-257662-viy65y72	260	12	82	82	CD
cord-257662-viy65y72	260	13	)	)	-RRB-
cord-257662-viy65y72	260	14	,	,	,
cord-257662-viy65y72	260	15	further	further	RB
cord-257662-viy65y72	260	16	supporting	support	VBG
cord-257662-viy65y72	260	17	a	a	DT
cord-257662-viy65y72	260	18	role	role	NN
cord-257662-viy65y72	260	19	for	for	IN
cord-257662-viy65y72	260	20	M2-polarized	M2-polarized	NNP
cord-257662-viy65y72	260	21	MDSC	MDSC	NNP
cord-257662-viy65y72	260	22	-	-	HYPH
cord-257662-viy65y72	260	23	like	like	JJ
cord-257662-viy65y72	260	24	cells	cell	NNS
cord-257662-viy65y72	260	25	in	in	IN
cord-257662-viy65y72	260	26	promoting	promote	VBG
cord-257662-viy65y72	260	27	viral	viral	JJ
cord-257662-viy65y72	260	28	persistence	persistence	NN
cord-257662-viy65y72	260	29	and	and	CC
cord-257662-viy65y72	260	30	immunopathology	immunopathology	NN
cord-257662-viy65y72	260	31	.	.	.
cord-257662-viy65y72	261	1	Helminth	Helminth	NNP
cord-257662-viy65y72	261	2	infection	infection	NN
cord-257662-viy65y72	261	3	induces	induce	VBZ
cord-257662-viy65y72	261	4	the	the	DT
cord-257662-viy65y72	261	5	expression	expression	NN
cord-257662-viy65y72	261	6	of	of	IN
cord-257662-viy65y72	261	7	type	type	NN
cord-257662-viy65y72	261	8	2	2	CD
cord-257662-viy65y72	261	9	cytokines	cytokine	NNS
cord-257662-viy65y72	261	10	and	and	CC
cord-257662-viy65y72	261	11	is	be	VBZ
cord-257662-viy65y72	261	12	associated	associate	VBN
cord-257662-viy65y72	261	13	with	with	IN
cord-257662-viy65y72	261	14	M2	M2	NNP
cord-257662-viy65y72	261	15	macrophage	macrophage	NN
cord-257662-viy65y72	261	16	activation	activation	NN
cord-257662-viy65y72	261	17	,	,	,
cord-257662-viy65y72	261	18	as	as	IN
cord-257662-viy65y72	261	19	determined	determine	VBN
cord-257662-viy65y72	261	20	by	by	IN
cord-257662-viy65y72	261	21	Arg1	Arg1	NNP
cord-257662-viy65y72	261	22	,	,	,
cord-257662-viy65y72	261	23	FIZZ1	FIZZ1	NNP
cord-257662-viy65y72	261	24	,	,	,
cord-257662-viy65y72	261	25	and	and	CC
cord-257662-viy65y72	261	26	Ym1	ym1	CD
cord-257662-viy65y72	261	27	expression	expression	NN
cord-257662-viy65y72	261	28	.	.	.
cord-257662-viy65y72	262	1	Indeed	indeed	RB
cord-257662-viy65y72	262	2	,	,	,
cord-257662-viy65y72	262	3	Osborne	Osborne	NNP
cord-257662-viy65y72	262	4	and	and	CC
cord-257662-viy65y72	262	5	colleagues	colleague	NNS
cord-257662-viy65y72	262	6	(	(	-LRB-
cord-257662-viy65y72	262	7	83	83	CD
cord-257662-viy65y72	262	8	)	)	-RRB-
cord-257662-viy65y72	262	9	found	find	VBD
cord-257662-viy65y72	262	10	that	that	IN
cord-257662-viy65y72	262	11	Arg1	Arg1	NNP
cord-257662-viy65y72	262	12	,	,	,
cord-257662-viy65y72	262	13	FIZZ1	FIZZ1	NNP
cord-257662-viy65y72	262	14	,	,	,
cord-257662-viy65y72	262	15	and	and	CC
cord-257662-viy65y72	262	16	Ym1	ym1	CD
cord-257662-viy65y72	262	17	were	be	VBD
cord-257662-viy65y72	262	18	highly	highly	RB
cord-257662-viy65y72	262	19	induced	induce	VBN
cord-257662-viy65y72	262	20	in	in	IN
cord-257662-viy65y72	262	21	the	the	DT
cord-257662-viy65y72	262	22	ileum	ileum	NN
cord-257662-viy65y72	262	23	of	of	IN
cord-257662-viy65y72	262	24	mice	mouse	NNS
cord-257662-viy65y72	262	25	infected	infect	VBN
cord-257662-viy65y72	262	26	with	with	IN
cord-257662-viy65y72	262	27	the	the	DT
cord-257662-viy65y72	262	28	helminth	helminth	JJ
cord-257662-viy65y72	262	29	Trichinella	trichinella	NN
cord-257662-viy65y72	262	30	spiralis	spiralis	NN
cord-257662-viy65y72	262	31	(	(	-LRB-
cord-257662-viy65y72	262	32	Ts	Ts	NNP
cord-257662-viy65y72	262	33	)	)	-RRB-
cord-257662-viy65y72	262	34	.	.	.
cord-257662-viy65y72	263	1	Interestingly	interestingly	RB
cord-257662-viy65y72	263	2	,	,	,
cord-257662-viy65y72	263	3	they	-PRON-	PRP
cord-257662-viy65y72	263	4	further	further	RB
cord-257662-viy65y72	263	5	showed	show	VBD
cord-257662-viy65y72	263	6	that	that	IN
cord-257662-viy65y72	263	7	co	co	NN
cord-257662-viy65y72	263	8	-	-	NN
cord-257662-viy65y72	263	9	infection	infection	NN
cord-257662-viy65y72	263	10	of	of	IN
cord-257662-viy65y72	263	11	mice	mouse	NNS
cord-257662-viy65y72	263	12	with	with	IN
cord-257662-viy65y72	263	13	Ts	Ts	NNP
cord-257662-viy65y72	263	14	and	and	CC
cord-257662-viy65y72	263	15	murine	murine	JJ
cord-257662-viy65y72	263	16	norovirus	norovirus	NN
cord-257662-viy65y72	263	17	(	(	-LRB-
cord-257662-viy65y72	263	18	MNV	MNV	NNP
cord-257662-viy65y72	263	19	)	)	-RRB-
cord-257662-viy65y72	263	20	resulted	result	VBD
cord-257662-viy65y72	263	21	in	in	IN
cord-257662-viy65y72	263	22	decreased	decreased	JJ
cord-257662-viy65y72	263	23	frequencies	frequency	NNS
cord-257662-viy65y72	263	24	and	and	CC
cord-257662-viy65y72	263	25	numbers	number	NNS
cord-257662-viy65y72	263	26	of	of	IN
cord-257662-viy65y72	263	27	MNV	mnv	NN
cord-257662-viy65y72	263	28	-	-	HYPH
cord-257662-viy65y72	263	29	specific	specific	JJ
cord-257662-viy65y72	263	30	CD8	CD8	NNP
cord-257662-viy65y72	263	31	+	+	SYM
cord-257662-viy65y72	263	32	and	and	CC
cord-257662-viy65y72	263	33	CD4	CD4	NNP
cord-257662-viy65y72	263	34	+	+	CC
cord-257662-viy65y72	263	35	T	t	NN
cord-257662-viy65y72	263	36	cells	cell	NNS
cord-257662-viy65y72	263	37	within	within	IN
cord-257662-viy65y72	263	38	the	the	DT
cord-257662-viy65y72	263	39	small	small	JJ
cord-257662-viy65y72	263	40	intestine	intestine	NN
cord-257662-viy65y72	263	41	and	and	CC
cord-257662-viy65y72	263	42	spleen	spleen	NNS
cord-257662-viy65y72	263	43	as	as	RB
cord-257662-viy65y72	263	44	well	well	RB
cord-257662-viy65y72	263	45	as	as	IN
cord-257662-viy65y72	263	46	decreased	decrease	VBD
cord-257662-viy65y72	263	47	polyfunctionality	polyfunctionality	NN
cord-257662-viy65y72	263	48	of	of	IN
cord-257662-viy65y72	263	49	these	these	DT
cord-257662-viy65y72	263	50	T	t	NN
cord-257662-viy65y72	263	51	cells	cell	NNS
cord-257662-viy65y72	263	52	,	,	,
cord-257662-viy65y72	263	53	compared	compare	VBN
cord-257662-viy65y72	263	54	to	to	IN
cord-257662-viy65y72	263	55	Ts	Ts	NNP
cord-257662-viy65y72	263	56	-	-	:
cord-257662-viy65y72	263	57	only	only	RB
cord-257662-viy65y72	263	58	infected	infected	JJ
cord-257662-viy65y72	263	59	mice	mouse	NNS
cord-257662-viy65y72	263	60	(	(	-LRB-
cord-257662-viy65y72	263	61	83	83	CD
cord-257662-viy65y72	263	62	)	)	-RRB-
cord-257662-viy65y72	263	63	.	.	.
cord-257662-viy65y72	264	1	Additionally	additionally	RB
cord-257662-viy65y72	264	2	,	,	,
cord-257662-viy65y72	264	3	the	the	DT
cord-257662-viy65y72	264	4	defective	defective	JJ
cord-257662-viy65y72	264	5	T	T	NNP
cord-257662-viy65y72	264	6	cell	cell	NN
cord-257662-viy65y72	264	7	responses	response	NNS
cord-257662-viy65y72	264	8	were	be	VBD
cord-257662-viy65y72	264	9	associated	associate	VBN
cord-257662-viy65y72	264	10	with	with	IN
cord-257662-viy65y72	264	11	increased	increase	VBN
cord-257662-viy65y72	264	12	viral	viral	JJ
cord-257662-viy65y72	264	13	loads	load	NNS
cord-257662-viy65y72	264	14	in	in	IN
cord-257662-viy65y72	264	15	the	the	DT
cord-257662-viy65y72	264	16	double	double	RB
cord-257662-viy65y72	264	17	-	-	HYPH
cord-257662-viy65y72	264	18	infected	infected	JJ
cord-257662-viy65y72	264	19	mice	mouse	NNS
cord-257662-viy65y72	264	20	compared	compare	VBN
cord-257662-viy65y72	264	21	to	to	IN
cord-257662-viy65y72	264	22	the	the	DT
cord-257662-viy65y72	264	23	mono	mono	NN
cord-257662-viy65y72	264	24	-	-	HYPH
cord-257662-viy65y72	264	25	infected	infect	VBN
cord-257662-viy65y72	264	26	controls	control	NNS
cord-257662-viy65y72	264	27	(	(	-LRB-
cord-257662-viy65y72	264	28	83	83	CD
cord-257662-viy65y72	264	29	)	)	-RRB-
cord-257662-viy65y72	264	30	,	,	,
cord-257662-viy65y72	264	31	suggesting	suggest	VBG
cord-257662-viy65y72	264	32	that	that	IN
cord-257662-viy65y72	264	33	Ts	Ts	NNP
cord-257662-viy65y72	264	34	-	-	HYPH
cord-257662-viy65y72	264	35	elicited	elicit	VBN
cord-257662-viy65y72	264	36	M2-activated	m2-activated	JJ
cord-257662-viy65y72	264	37	macrophages	macrophage	NNS
cord-257662-viy65y72	264	38	inhibited	inhibit	VBD
cord-257662-viy65y72	264	39	the	the	DT
cord-257662-viy65y72	264	40	antiviral	antiviral	JJ
cord-257662-viy65y72	264	41	T	T	NNP
cord-257662-viy65y72	264	42	cell	cell	NN
cord-257662-viy65y72	264	43	response	response	NN
cord-257662-viy65y72	264	44	to	to	IN
cord-257662-viy65y72	264	45	MNV	MNV	NNP
cord-257662-viy65y72	264	46	.	.	.
cord-257662-viy65y72	265	1	Lastly	lastly	RB
cord-257662-viy65y72	265	2	,	,	,
cord-257662-viy65y72	265	3	neutralization	neutralization	NN
cord-257662-viy65y72	265	4	of	of	IN
cord-257662-viy65y72	265	5	Ym1	ym1	NN
cord-257662-viy65y72	265	6	,	,	,
cord-257662-viy65y72	265	7	a	a	DT
cord-257662-viy65y72	265	8	chitinase	chitinase	NN
cord-257662-viy65y72	265	9	-	-	HYPH
cord-257662-viy65y72	265	10	like	like	JJ
cord-257662-viy65y72	265	11	molecule	molecule	NN
cord-257662-viy65y72	265	12	,	,	,
cord-257662-viy65y72	265	13	in	in	IN
cord-257662-viy65y72	265	14	co	co	JJ
cord-257662-viy65y72	265	15	-	-	JJ
cord-257662-viy65y72	265	16	infected	infected	JJ
cord-257662-viy65y72	265	17	mice	mouse	NNS
cord-257662-viy65y72	265	18	partially	partially	RB
cord-257662-viy65y72	265	19	restored	restore	VBD
cord-257662-viy65y72	265	20	antiviral	antiviral	JJ
cord-257662-viy65y72	265	21	immunity	immunity	NN
cord-257662-viy65y72	265	22	and	and	CC
cord-257662-viy65y72	265	23	was	be	VBD
cord-257662-viy65y72	265	24	associated	associate	VBN
cord-257662-viy65y72	265	25	with	with	IN
cord-257662-viy65y72	265	26	enhanced	enhanced	JJ
cord-257662-viy65y72	265	27	control	control	NN
cord-257662-viy65y72	265	28	of	of	IN
cord-257662-viy65y72	265	29	viral	viral	JJ
cord-257662-viy65y72	265	30	replication	replication	NN
cord-257662-viy65y72	265	31	(	(	-LRB-
cord-257662-viy65y72	265	32	83	83	CD
cord-257662-viy65y72	265	33	)	)	-RRB-
cord-257662-viy65y72	265	34	.	.	.
cord-257662-viy65y72	266	1	These	these	DT
cord-257662-viy65y72	266	2	data	datum	NNS
cord-257662-viy65y72	266	3	point	point	NN
cord-257662-viy65y72	266	4	to	to	IN
cord-257662-viy65y72	266	5	a	a	DT
cord-257662-viy65y72	266	6	new	new	JJ
cord-257662-viy65y72	266	7	mechanism	mechanism	NN
cord-257662-viy65y72	266	8	by	by	IN
cord-257662-viy65y72	266	9	which	which	WDT
cord-257662-viy65y72	266	10	Arg1-expressing	arg1-expresse	VBG
cord-257662-viy65y72	266	11	macrophages	macrophage	NNS
cord-257662-viy65y72	266	12	inhibit	inhibit	VBP
cord-257662-viy65y72	266	13	antiviral	antiviral	JJ
cord-257662-viy65y72	266	14	responses	response	NNS
cord-257662-viy65y72	266	15	.	.	.
cord-257662-viy65y72	267	1	Cumulatively	cumulatively	RB
cord-257662-viy65y72	267	2	,	,	,
cord-257662-viy65y72	267	3	these	these	DT
cord-257662-viy65y72	267	4	data	datum	NNS
cord-257662-viy65y72	267	5	are	be	VBP
cord-257662-viy65y72	267	6	reminiscent	reminiscent	JJ
cord-257662-viy65y72	267	7	of	of	IN
cord-257662-viy65y72	267	8	macrophages	macrophage	NNS
cord-257662-viy65y72	267	9	found	find	VBN
cord-257662-viy65y72	267	10	in	in	IN
cord-257662-viy65y72	267	11	tumors	tumor	NNS
cord-257662-viy65y72	267	12	(	(	-LRB-
cord-257662-viy65y72	267	13	e.g.	e.g.	RB
cord-257662-viy65y72	267	14	,	,	,
cord-257662-viy65y72	267	15	MDSCs	MDSCs	NNP
cord-257662-viy65y72	267	16	,	,	,
cord-257662-viy65y72	267	17	TAMs	tam	NNS
cord-257662-viy65y72	267	18	)	)	-RRB-
cord-257662-viy65y72	267	19	that	that	WDT
cord-257662-viy65y72	267	20	have	have	VBP
cord-257662-viy65y72	267	21	been	be	VBN
cord-257662-viy65y72	267	22	shown	show	VBN
cord-257662-viy65y72	267	23	to	to	TO
cord-257662-viy65y72	267	24	suppress	suppress	VB
cord-257662-viy65y72	267	25	anti	anti	JJ
cord-257662-viy65y72	267	26	-	-	JJ
cord-257662-viy65y72	267	27	tumor	tumor	JJ
cord-257662-viy65y72	267	28	T	t	NN
cord-257662-viy65y72	267	29	cell	cell	NN
cord-257662-viy65y72	267	30	responses	response	NNS
cord-257662-viy65y72	267	31	via	via	IN
cord-257662-viy65y72	267	32	a	a	DT
cord-257662-viy65y72	267	33	variety	variety	NN
cord-257662-viy65y72	267	34	of	of	IN
cord-257662-viy65y72	267	35	NO	no	NN
cord-257662-viy65y72	267	36	-	-	HYPH
cord-257662-viy65y72	267	37	and	and	CC
cord-257662-viy65y72	267	38	/	/	SYM
cord-257662-viy65y72	267	39	or	or	CC
cord-257662-viy65y72	267	40	Arg1-dependent	arg1-dependent	NN
cord-257662-viy65y72	267	41	mechanisms	mechanism	NNS
cord-257662-viy65y72	267	42	(	(	-LRB-
cord-257662-viy65y72	267	43	4	4	CD
cord-257662-viy65y72	267	44	,	,	,
cord-257662-viy65y72	267	45	5	5	CD
cord-257662-viy65y72	267	46	)	)	-RRB-
cord-257662-viy65y72	267	47	.	.	.
cord-257662-viy65y72	268	1	Indeed	indeed	RB
cord-257662-viy65y72	268	2	,	,	,
cord-257662-viy65y72	268	3	in	in	IN
cord-257662-viy65y72	268	4	a	a	DT
cord-257662-viy65y72	268	5	mouse	mouse	NN
cord-257662-viy65y72	268	6	model	model	NN
cord-257662-viy65y72	268	7	of	of	IN
cord-257662-viy65y72	268	8	human	human	JJ
cord-257662-viy65y72	268	9	papillomavirus	papillomavirus	NN
cord-257662-viy65y72	268	10	(	(	-LRB-
cord-257662-viy65y72	268	11	HPV)-induced	hpv)-induced	CD
cord-257662-viy65y72	268	12	cancer	cancer	NN
cord-257662-viy65y72	268	13	,	,	,
cord-257662-viy65y72	268	14	Arg1-expressing	arg1-expresse	VBG
cord-257662-viy65y72	268	15	CD11b	CD11b	NNS
cord-257662-viy65y72	268	16	+	+	SYM
cord-257662-viy65y72	268	17	F4/80	F4/80	NNS
cord-257662-viy65y72	268	18	+	+	CC
cord-257662-viy65y72	268	19	macrophages	macrophage	NNS
cord-257662-viy65y72	268	20	infiltrated	infiltrate	VBD
cord-257662-viy65y72	268	21	the	the	DT
cord-257662-viy65y72	268	22	tumors	tumor	NNS
cord-257662-viy65y72	268	23	and	and	CC
cord-257662-viy65y72	268	24	inhibited	inhibit	VBN
cord-257662-viy65y72	268	25	T	t	NN
cord-257662-viy65y72	268	26	cell	cell	NN
cord-257662-viy65y72	268	27	responses	response	NNS
cord-257662-viy65y72	268	28	,	,	,
cord-257662-viy65y72	268	29	including	include	VBG
cord-257662-viy65y72	268	30	virus	virus	NN
cord-257662-viy65y72	268	31	-	-	HYPH
cord-257662-viy65y72	268	32	specific	specific	JJ
cord-257662-viy65y72	268	33	T	t	NN
cord-257662-viy65y72	268	34	cells	cell	NNS
cord-257662-viy65y72	268	35	,	,	,
cord-257662-viy65y72	268	36	by	by	IN
cord-257662-viy65y72	268	37	suppressing	suppress	VBG
cord-257662-viy65y72	268	38	T	t	NN
cord-257662-viy65y72	268	39	cell	cell	NN
cord-257662-viy65y72	268	40	proliferation	proliferation	NN
cord-257662-viy65y72	268	41	and	and	CC
cord-257662-viy65y72	268	42	promoting	promote	VBG
cord-257662-viy65y72	268	43	a	a	DT
cord-257662-viy65y72	268	44	regulatory	regulatory	JJ
cord-257662-viy65y72	268	45	phenotype	phenotype	NN
cord-257662-viy65y72	268	46	(	(	-LRB-
cord-257662-viy65y72	268	47	103	103	CD
cord-257662-viy65y72	268	48	)	)	-RRB-
cord-257662-viy65y72	268	49	.	.	.
cord-257662-viy65y72	269	1	Moreover	moreover	RB
cord-257662-viy65y72	269	2	,	,	,
cord-257662-viy65y72	269	3	depletion	depletion	NN
cord-257662-viy65y72	269	4	of	of	IN
cord-257662-viy65y72	269	5	the	the	DT
cord-257662-viy65y72	269	6	tumor	tumor	NN
cord-257662-viy65y72	269	7	-	-	HYPH
cord-257662-viy65y72	269	8	infiltrating	infiltrate	VBG
cord-257662-viy65y72	269	9	macrophages	macrophage	NNS
cord-257662-viy65y72	269	10	resulted	result	VBD
cord-257662-viy65y72	269	11	in	in	IN
cord-257662-viy65y72	269	12	reduced	reduce	VBN
cord-257662-viy65y72	269	13	tumor	tumor	NN
cord-257662-viy65y72	269	14	growth	growth	NN
cord-257662-viy65y72	269	15	and	and	CC
cord-257662-viy65y72	269	16	increased	increase	VBN
cord-257662-viy65y72	269	17	tumor	tumor	NN
cord-257662-viy65y72	269	18	infiltration	infiltration	NN
cord-257662-viy65y72	269	19	by	by	IN
cord-257662-viy65y72	269	20	virus	virus	NN
cord-257662-viy65y72	269	21	-	-	HYPH
cord-257662-viy65y72	269	22	specific	specific	JJ
cord-257662-viy65y72	269	23	CD8	CD8	NNP
cord-257662-viy65y72	269	24	+	+	CC
cord-257662-viy65y72	269	25	T	t	NN
cord-257662-viy65y72	269	26	cells	cell	NNS
cord-257662-viy65y72	269	27	(	(	-LRB-
cord-257662-viy65y72	269	28	103	103	CD
cord-257662-viy65y72	269	29	)	)	-RRB-
cord-257662-viy65y72	269	30	.	.	.
cord-257662-viy65y72	270	1	Thus	thus	RB
cord-257662-viy65y72	270	2	,	,	,
cord-257662-viy65y72	270	3	increasing	increase	VBG
cord-257662-viy65y72	270	4	evidence	evidence	NN
cord-257662-viy65y72	270	5	points	point	NNS
cord-257662-viy65y72	270	6	to	to	IN
cord-257662-viy65y72	270	7	a	a	DT
cord-257662-viy65y72	270	8	direct	direct	JJ
cord-257662-viy65y72	270	9	role	role	NN
cord-257662-viy65y72	270	10	for	for	IN
cord-257662-viy65y72	270	11	arginase	arginase	NN
cord-257662-viy65y72	270	12	-	-	HYPH
cord-257662-viy65y72	270	13	expressing	express	VBG
cord-257662-viy65y72	270	14	M2-polarized	m2-polarize	VBN
cord-257662-viy65y72	270	15	cells	cell	NNS
cord-257662-viy65y72	270	16	in	in	IN
cord-257662-viy65y72	270	17	the	the	DT
cord-257662-viy65y72	270	18	suppression	suppression	NN
cord-257662-viy65y72	270	19	of	of	IN
cord-257662-viy65y72	270	20	antiviral	antiviral	JJ
cord-257662-viy65y72	270	21	T	T	NNP
cord-257662-viy65y72	270	22	cell	cell	NN
cord-257662-viy65y72	270	23	responses	response	NNS
cord-257662-viy65y72	270	24	and	and	CC
cord-257662-viy65y72	270	25	the	the	DT
cord-257662-viy65y72	270	26	persistence	persistence	NN
cord-257662-viy65y72	270	27	of	of	IN
cord-257662-viy65y72	270	28	a	a	DT
cord-257662-viy65y72	270	29	variety	variety	NN
cord-257662-viy65y72	270	30	of	of	IN
cord-257662-viy65y72	270	31	important	important	JJ
cord-257662-viy65y72	270	32	pathogenic	pathogenic	JJ
cord-257662-viy65y72	270	33	viruses	virus	NNS
cord-257662-viy65y72	270	34	.	.	.
cord-257662-viy65y72	271	1	In	in	IN
cord-257662-viy65y72	271	2	addition	addition	NN
cord-257662-viy65y72	271	3	to	to	IN
cord-257662-viy65y72	271	4	the	the	DT
cord-257662-viy65y72	271	5	actions	action	NNS
cord-257662-viy65y72	271	6	of	of	IN
cord-257662-viy65y72	271	7	iNOS	inos	CD
cord-257662-viy65y72	271	8	and	and	CC
cord-257662-viy65y72	271	9	Arg1	Arg1	NNP
cord-257662-viy65y72	271	10	,	,	,
cord-257662-viy65y72	271	11	MDSC	MDSC	NNP
cord-257662-viy65y72	271	12	-	-	HYPH
cord-257662-viy65y72	271	13	like	like	JJ
cord-257662-viy65y72	271	14	cells	cell	NNS
cord-257662-viy65y72	271	15	can	can	MD
cord-257662-viy65y72	271	16	employ	employ	VB
cord-257662-viy65y72	271	17	other	other	JJ
cord-257662-viy65y72	271	18	mechanisms	mechanism	NNS
cord-257662-viy65y72	271	19	to	to	TO
cord-257662-viy65y72	271	20	promote	promote	VB
cord-257662-viy65y72	271	21	chronic	chronic	JJ
cord-257662-viy65y72	271	22	viral	viral	JJ
cord-257662-viy65y72	271	23	infections	infection	NNS
cord-257662-viy65y72	271	24	,	,	,
cord-257662-viy65y72	271	25	which	which	WDT
cord-257662-viy65y72	271	26	were	be	VBD
cord-257662-viy65y72	271	27	recently	recently	RB
cord-257662-viy65y72	271	28	reviewed	review	VBN
cord-257662-viy65y72	271	29	by	by	IN
cord-257662-viy65y72	271	30	Goh	Goh	NNP
cord-257662-viy65y72	271	31	and	and	CC
cord-257662-viy65y72	271	32	colleagues	colleague	NNS
cord-257662-viy65y72	271	33	(	(	-LRB-
cord-257662-viy65y72	271	34	104	104	CD
cord-257662-viy65y72	271	35	)	)	-RRB-
cord-257662-viy65y72	271	36	.	.	.
cord-257662-viy65y72	272	1	In	in	IN
cord-257662-viy65y72	272	2	contrast	contrast	NN
cord-257662-viy65y72	272	3	to	to	IN
cord-257662-viy65y72	272	4	some	some	DT
cord-257662-viy65y72	272	5	parasitic	parasitic	JJ
cord-257662-viy65y72	272	6	infections	infection	NNS
cord-257662-viy65y72	272	7	where	where	WRB
cord-257662-viy65y72	272	8	M2	m2	JJ
cord-257662-viy65y72	272	9	macrophages	macrophage	NNS
cord-257662-viy65y72	272	10	limit	limit	VBP
cord-257662-viy65y72	272	11	Th2	th2	CD
cord-257662-viy65y72	272	12	cell	cell	NN
cord-257662-viy65y72	272	13	-	-	HYPH
cord-257662-viy65y72	272	14	mediated	mediate	VBN
cord-257662-viy65y72	272	15	immunopathology	immunopathology	NN
cord-257662-viy65y72	272	16	,	,	,
cord-257662-viy65y72	272	17	M2-polarized	m2-polarize	VBN
cord-257662-viy65y72	272	18	macrophages	macrophage	NNS
cord-257662-viy65y72	272	19	have	have	VBP
cord-257662-viy65y72	272	20	been	be	VBN
cord-257662-viy65y72	272	21	shown	show	VBN
cord-257662-viy65y72	272	22	to	to	TO
cord-257662-viy65y72	272	23	promote	promote	VB
cord-257662-viy65y72	272	24	immunopathology	immunopathology	NN
cord-257662-viy65y72	272	25	in	in	IN
cord-257662-viy65y72	272	26	some	some	DT
cord-257662-viy65y72	272	27	viral	viral	JJ
cord-257662-viy65y72	272	28	infections	infection	NNS
cord-257662-viy65y72	272	29	.	.	.
cord-257662-viy65y72	273	1	For	for	IN
cord-257662-viy65y72	273	2	example	example	NN
cord-257662-viy65y72	273	3	,	,	,
cord-257662-viy65y72	273	4	it	-PRON-	PRP
cord-257662-viy65y72	273	5	was	be	VBD
cord-257662-viy65y72	273	6	recently	recently	RB
cord-257662-viy65y72	273	7	demonstrated	demonstrate	VBN
cord-257662-viy65y72	273	8	that	that	IN
cord-257662-viy65y72	273	9	SARS	SARS	NNP
cord-257662-viy65y72	273	10	-	-	HYPH
cord-257662-viy65y72	273	11	CoV	CoV	NNP
cord-257662-viy65y72	273	12	infection	infection	NN
cord-257662-viy65y72	273	13	of	of	IN
cord-257662-viy65y72	273	14	mice	mouse	NNS
cord-257662-viy65y72	273	15	induced	induce	VBN
cord-257662-viy65y72	273	16	suppressive	suppressive	JJ
cord-257662-viy65y72	273	17	alveolar	alveolar	NN
cord-257662-viy65y72	273	18	macrophages	macrophage	NNS
cord-257662-viy65y72	273	19	that	that	WDT
cord-257662-viy65y72	273	20	inhibited	inhibit	VBD
cord-257662-viy65y72	273	21	the	the	DT
cord-257662-viy65y72	273	22	induction	induction	NN
cord-257662-viy65y72	273	23	of	of	IN
cord-257662-viy65y72	273	24	antiviral	antiviral	JJ
cord-257662-viy65y72	273	25	T	T	NNP
cord-257662-viy65y72	273	26	cell	cell	NN
cord-257662-viy65y72	273	27	responses	response	NNS
cord-257662-viy65y72	273	28	,	,	,
cord-257662-viy65y72	273	29	a	a	DT
cord-257662-viy65y72	273	30	phenotype	phenotype	NN
cord-257662-viy65y72	273	31	that	that	WDT
cord-257662-viy65y72	273	32	was	be	VBD
cord-257662-viy65y72	273	33	reversed	reverse	VBN
cord-257662-viy65y72	273	34	by	by	IN
cord-257662-viy65y72	273	35	the	the	DT
cord-257662-viy65y72	273	36	adoptive	adoptive	JJ
cord-257662-viy65y72	273	37	transfer	transfer	NN
cord-257662-viy65y72	273	38	of	of	IN
cord-257662-viy65y72	273	39	activated	activate	VBN
cord-257662-viy65y72	273	40	bone	bone	NN
cord-257662-viy65y72	273	41	marrow	marrow	NN
cord-257662-viy65y72	273	42	-	-	HYPH
cord-257662-viy65y72	273	43	derived	derive	VBN
cord-257662-viy65y72	273	44	DCs	dc	NNS
cord-257662-viy65y72	273	45	into	into	IN
cord-257662-viy65y72	273	46	mice	mouse	NNS
cord-257662-viy65y72	273	47	prior	prior	RB
cord-257662-viy65y72	273	48	to	to	IN
cord-257662-viy65y72	273	49	virus	virus	NN
cord-257662-viy65y72	273	50	infection	infection	NN
cord-257662-viy65y72	273	51	(	(	-LRB-
cord-257662-viy65y72	273	52	56	56	CD
cord-257662-viy65y72	273	53	)	)	-RRB-
cord-257662-viy65y72	273	54	.	.	.
cord-257662-viy65y72	274	1	Additionally	additionally	RB
cord-257662-viy65y72	274	2	,	,	,
cord-257662-viy65y72	274	3	SARS	SARS	NNP
cord-257662-viy65y72	274	4	-	-	HYPH
cord-257662-viy65y72	274	5	CoV	CoV	NNP
cord-257662-viy65y72	274	6	-	-	HYPH
cord-257662-viy65y72	274	7	infected	infect	VBN
cord-257662-viy65y72	274	8	mice	mouse	NNS
cord-257662-viy65y72	274	9	lacking	lack	VBG
cord-257662-viy65y72	274	10	hematopoietic	hematopoietic	JJ
cord-257662-viy65y72	274	11	STAT-1	stat-1	NN
cord-257662-viy65y72	274	12	expression	expression	NN
cord-257662-viy65y72	274	13	were	be	VBD
cord-257662-viy65y72	274	14	shown	show	VBN
cord-257662-viy65y72	274	15	to	to	TO
cord-257662-viy65y72	274	16	have	have	VB
cord-257662-viy65y72	274	17	greater	great	JJR
cord-257662-viy65y72	274	18	weight	weight	NN
cord-257662-viy65y72	274	19	loss	loss	NN
cord-257662-viy65y72	274	20	and	and	CC
cord-257662-viy65y72	274	21	lung	lung	NN
cord-257662-viy65y72	274	22	pathology	pathology	NN
cord-257662-viy65y72	274	23	,	,	,
cord-257662-viy65y72	274	24	and	and	CC
cord-257662-viy65y72	274	25	this	this	DT
cord-257662-viy65y72	274	26	was	be	VBD
cord-257662-viy65y72	274	27	associated	associate	VBN
cord-257662-viy65y72	274	28	with	with	IN
cord-257662-viy65y72	274	29	the	the	DT
cord-257662-viy65y72	274	30	activation	activation	NN
cord-257662-viy65y72	274	31	of	of	IN
cord-257662-viy65y72	274	32	M2	M2	NNP
cord-257662-viy65y72	274	33	macrophages	macrophage	NNS
cord-257662-viy65y72	274	34	(	(	-LRB-
cord-257662-viy65y72	274	35	57	57	CD
cord-257662-viy65y72	274	36	)	)	-RRB-
cord-257662-viy65y72	274	37	.	.	.
cord-257662-viy65y72	275	1	To	to	TO
cord-257662-viy65y72	275	2	further	further	RB
cord-257662-viy65y72	275	3	test	test	VB
cord-257662-viy65y72	275	4	the	the	DT
cord-257662-viy65y72	275	5	role	role	NN
cord-257662-viy65y72	275	6	of	of	IN
cord-257662-viy65y72	275	7	M2	M2	NNP
cord-257662-viy65y72	275	8	macrophages	macrophage	NNS
cord-257662-viy65y72	275	9	in	in	IN
cord-257662-viy65y72	275	10	enhanced	enhanced	JJ
cord-257662-viy65y72	275	11	pathogenesis	pathogenesis	NN
cord-257662-viy65y72	275	12	following	follow	VBG
cord-257662-viy65y72	275	13	SARS	SARS	NNP
cord-257662-viy65y72	275	14	-	-	HYPH
cord-257662-viy65y72	275	15	CoV	CoV	NNP
cord-257662-viy65y72	275	16	infection	infection	NN
cord-257662-viy65y72	275	17	,	,	,
cord-257662-viy65y72	275	18	the	the	DT
cord-257662-viy65y72	275	19	authors	author	NNS
cord-257662-viy65y72	275	20	generated	generate	VBD
cord-257662-viy65y72	275	21	STAT-1	STAT-1	NNS
cord-257662-viy65y72	275	22	/	/	SYM
cord-257662-viy65y72	275	23	STAT-6	stat-6	NN
cord-257662-viy65y72	275	24	double	double	JJ
cord-257662-viy65y72	275	25	knockout	knockout	NN
cord-257662-viy65y72	275	26	mice	mouse	NNS
cord-257662-viy65y72	275	27	due	due	JJ
cord-257662-viy65y72	275	28	to	to	IN
cord-257662-viy65y72	275	29	the	the	DT
cord-257662-viy65y72	275	30	established	establish	VBN
cord-257662-viy65y72	275	31	role	role	NN
cord-257662-viy65y72	275	32	for	for	IN
cord-257662-viy65y72	275	33	STAT-6	STAT-6	NNP
cord-257662-viy65y72	275	34	in	in	IN
cord-257662-viy65y72	275	35	driving	drive	VBG
cord-257662-viy65y72	275	36	M2	m2	JJ
cord-257662-viy65y72	275	37	macrophage	macrophage	NN
cord-257662-viy65y72	275	38	activation	activation	NN
cord-257662-viy65y72	275	39	in	in	IN
cord-257662-viy65y72	275	40	response	response	NN
cord-257662-viy65y72	275	41	to	to	IN
cord-257662-viy65y72	275	42	IL-4	IL-4	NNP
cord-257662-viy65y72	275	43	/	/	SYM
cord-257662-viy65y72	275	44	IL-13	IL-13	NNP
cord-257662-viy65y72	275	45	stimulation	stimulation	NN
cord-257662-viy65y72	275	46	.	.	.
cord-257662-viy65y72	276	1	STAT-1	STAT-1	NNS
cord-257662-viy65y72	276	2	/	/	SYM
cord-257662-viy65y72	276	3	STAT-6	stat-6	NN
cord-257662-viy65y72	276	4	double	double	JJ
cord-257662-viy65y72	276	5	knockout	knockout	NN
cord-257662-viy65y72	276	6	mice	mouse	NNS
cord-257662-viy65y72	276	7	,	,	,
cord-257662-viy65y72	276	8	which	which	WDT
cord-257662-viy65y72	276	9	reversed	reverse	VBD
cord-257662-viy65y72	276	10	the	the	DT
cord-257662-viy65y72	276	11	upregulation	upregulation	NN
cord-257662-viy65y72	276	12	of	of	IN
cord-257662-viy65y72	276	13	M2	M2	NNP
cord-257662-viy65y72	276	14	macrophages	macrophage	NNS
cord-257662-viy65y72	276	15	observed	observe	VBN
cord-257662-viy65y72	276	16	in	in	IN
cord-257662-viy65y72	276	17	STAT-1-deficient	stat-1-deficient	NN
cord-257662-viy65y72	277	1	mice	mouse	NNS
cord-257662-viy65y72	277	2	,	,	,
cord-257662-viy65y72	277	3	had	have	VBD
cord-257662-viy65y72	277	4	reduced	reduce	VBN
cord-257662-viy65y72	277	5	lung	lung	NN
cord-257662-viy65y72	277	6	disease	disease	NN
cord-257662-viy65y72	277	7	and	and	CC
cord-257662-viy65y72	277	8	prefibrotic	prefibrotic	JJ
cord-257662-viy65y72	277	9	lesions	lesion	NNS
cord-257662-viy65y72	277	10	(	(	-LRB-
cord-257662-viy65y72	277	11	57	57	CD
cord-257662-viy65y72	277	12	)	)	-RRB-
cord-257662-viy65y72	277	13	.	.	.
cord-257662-viy65y72	278	1	These	these	DT
cord-257662-viy65y72	278	2	data	datum	NNS
cord-257662-viy65y72	278	3	support	support	VBP
cord-257662-viy65y72	278	4	the	the	DT
cord-257662-viy65y72	278	5	notion	notion	NN
cord-257662-viy65y72	278	6	that	that	IN
cord-257662-viy65y72	278	7	M2	M2	NNP
cord-257662-viy65y72	278	8	macrophages	macrophage	NNS
cord-257662-viy65y72	278	9	contribute	contribute	VBP
cord-257662-viy65y72	278	10	to	to	IN
cord-257662-viy65y72	278	11	SARS	SARS	NNP
cord-257662-viy65y72	278	12	-	-	HYPH
cord-257662-viy65y72	278	13	CoV	CoV	NNP
cord-257662-viy65y72	278	14	pathogenesis	pathogenesis	NN
cord-257662-viy65y72	278	15	.	.	.
cord-257662-viy65y72	279	1	In	in	IN
cord-257662-viy65y72	279	2	another	another	DT
cord-257662-viy65y72	279	3	example	example	NN
cord-257662-viy65y72	279	4	,	,	,
cord-257662-viy65y72	279	5	mice	mouse	NNS
cord-257662-viy65y72	279	6	deficient	deficient	JJ
cord-257662-viy65y72	279	7	in	in	IN
cord-257662-viy65y72	279	8	the	the	DT
cord-257662-viy65y72	279	9	IFN	IFN	NNP
cord-257662-viy65y72	279	10	-	-	HYPH
cord-257662-viy65y72	279	11	γR	γR	NNP
cord-257662-viy65y72	279	12	exhibit	exhibit	VBP
cord-257662-viy65y72	279	13	more	more	RBR
cord-257662-viy65y72	279	14	severe	severe	JJ
cord-257662-viy65y72	279	15	disease	disease	NN
cord-257662-viy65y72	279	16	following	follow	VBG
cord-257662-viy65y72	279	17	infection	infection	NN
cord-257662-viy65y72	279	18	with	with	IN
cord-257662-viy65y72	279	19	murine	murine	JJ
cord-257662-viy65y72	279	20	gammaherpesvirus-68	gammaherpesvirus-68	NN
cord-257662-viy65y72	279	21	(	(	-LRB-
cord-257662-viy65y72	279	22	MHV-68	MHV-68	NNP
cord-257662-viy65y72	279	23	)	)	-RRB-
cord-257662-viy65y72	279	24	,	,	,
cord-257662-viy65y72	279	25	including	include	VBG
cord-257662-viy65y72	279	26	interstitial	interstitial	JJ
cord-257662-viy65y72	279	27	and	and	CC
cord-257662-viy65y72	279	28	intra	intra	JJ
cord-257662-viy65y72	279	29	-	-	JJ
cord-257662-viy65y72	279	30	alveolar	alveolar	JJ
cord-257662-viy65y72	279	31	fibrosis	fibrosis	NN
cord-257662-viy65y72	279	32	that	that	WDT
cord-257662-viy65y72	279	33	is	be	VBZ
cord-257662-viy65y72	279	34	reminiscent	reminiscent	JJ
cord-257662-viy65y72	279	35	of	of	IN
cord-257662-viy65y72	279	36	idiopathic	idiopathic	JJ
cord-257662-viy65y72	279	37	pulmonary	pulmonary	JJ
cord-257662-viy65y72	279	38	fibrosis	fibrosis	NN
cord-257662-viy65y72	279	39	(	(	-LRB-
cord-257662-viy65y72	279	40	IPF	IPF	NNP
cord-257662-viy65y72	279	41	)	)	-RRB-
cord-257662-viy65y72	279	42	in	in	IN
cord-257662-viy65y72	279	43	human	human	JJ
cord-257662-viy65y72	279	44	beings	being	NNS
cord-257662-viy65y72	279	45	.	.	.
cord-257662-viy65y72	280	1	In	in	IN
cord-257662-viy65y72	280	2	this	this	DT
cord-257662-viy65y72	280	3	model	model	NN
cord-257662-viy65y72	280	4	,	,	,
cord-257662-viy65y72	280	5	alveolar	alveolar	JJ
cord-257662-viy65y72	280	6	macrophages	macrophage	NNS
cord-257662-viy65y72	280	7	were	be	VBD
cord-257662-viy65y72	280	8	recruited	recruit	VBN
cord-257662-viy65y72	280	9	to	to	IN
cord-257662-viy65y72	280	10	the	the	DT
cord-257662-viy65y72	280	11	lungs	lung	NNS
cord-257662-viy65y72	280	12	of	of	IN
cord-257662-viy65y72	280	13	MHV-68-infected	mhv-68-infected	JJ
cord-257662-viy65y72	280	14	IFN	IFN	NNP
cord-257662-viy65y72	280	15	-	-	HYPH
cord-257662-viy65y72	280	16	γR	γR	NNP
cord-257662-viy65y72	281	1	−/−	−/−	NNP
cord-257662-viy65y72	281	2	mice	mouse	NNS
cord-257662-viy65y72	281	3	,	,	,
cord-257662-viy65y72	281	4	were	be	VBD
cord-257662-viy65y72	281	5	associated	associate	VBN
cord-257662-viy65y72	281	6	with	with	IN
cord-257662-viy65y72	281	7	areas	area	NNS
cord-257662-viy65y72	281	8	of	of	IN
cord-257662-viy65y72	281	9	fibrosis	fibrosis	NN
cord-257662-viy65y72	281	10	,	,	,
cord-257662-viy65y72	281	11	and	and	CC
cord-257662-viy65y72	281	12	exhibited	exhibit	VBD
cord-257662-viy65y72	281	13	a	a	DT
cord-257662-viy65y72	281	14	M2-polarized	m2-polarize	VBN
cord-257662-viy65y72	281	15	phenotype	phenotype	NN
cord-257662-viy65y72	281	16	characterized	characterize	VBN
cord-257662-viy65y72	281	17	by	by	IN
cord-257662-viy65y72	281	18	the	the	DT
cord-257662-viy65y72	281	19	expression	expression	NN
cord-257662-viy65y72	281	20	of	of	IN
cord-257662-viy65y72	281	21	FIZZ1	FIZZ1	NNP
cord-257662-viy65y72	281	22	,	,	,
cord-257662-viy65y72	281	23	Ym1	ym1	CD
cord-257662-viy65y72	281	24	,	,	,
cord-257662-viy65y72	281	25	and	and	CC
cord-257662-viy65y72	281	26	Arg1	Arg1	NNP
cord-257662-viy65y72	281	27	(	(	-LRB-
cord-257662-viy65y72	281	28	61	61	CD
cord-257662-viy65y72	281	29	)	)	-RRB-
cord-257662-viy65y72	281	30	.	.	.
cord-257662-viy65y72	282	1	Additionally	additionally	RB
cord-257662-viy65y72	282	2	,	,	,
cord-257662-viy65y72	282	3	lung	lung	NN
cord-257662-viy65y72	282	4	tissue	tissue	NN
cord-257662-viy65y72	282	5	from	from	IN
cord-257662-viy65y72	282	6	patients	patient	NNS
cord-257662-viy65y72	282	7	with	with	IN
cord-257662-viy65y72	282	8	IPF	IPF	NNP
cord-257662-viy65y72	282	9	showed	show	VBD
cord-257662-viy65y72	282	10	increased	increased	JJ
cord-257662-viy65y72	282	11	expression	expression	NN
cord-257662-viy65y72	282	12	of	of	IN
cord-257662-viy65y72	282	13	Arg1	Arg1	NNP
cord-257662-viy65y72	282	14	in	in	IN
cord-257662-viy65y72	282	15	alveolar	alveolar	JJ
cord-257662-viy65y72	282	16	macrophages	macrophage	NNS
cord-257662-viy65y72	282	17	compared	compare	VBN
cord-257662-viy65y72	282	18	with	with	IN
cord-257662-viy65y72	282	19	normal	normal	JJ
cord-257662-viy65y72	282	20	lung	lung	NN
cord-257662-viy65y72	282	21	(	(	-LRB-
cord-257662-viy65y72	282	22	61	61	CD
cord-257662-viy65y72	282	23	)	)	-RRB-
cord-257662-viy65y72	282	24	.	.	.
cord-257662-viy65y72	283	1	These	these	DT
cord-257662-viy65y72	283	2	results	result	NNS
cord-257662-viy65y72	283	3	suggest	suggest	VBP
cord-257662-viy65y72	283	4	that	that	IN
cord-257662-viy65y72	283	5	virus	virus	NN
cord-257662-viy65y72	283	6	-	-	HYPH
cord-257662-viy65y72	283	7	induced	induce	VBN
cord-257662-viy65y72	283	8	upregulation	upregulation	NN
cord-257662-viy65y72	283	9	of	of	IN
cord-257662-viy65y72	283	10	Arg1	Arg1	NNP
cord-257662-viy65y72	283	11	could	could	MD
cord-257662-viy65y72	283	12	be	be	VB
cord-257662-viy65y72	283	13	mediating	mediate	VBG
cord-257662-viy65y72	283	14	lung	lung	NN
cord-257662-viy65y72	283	15	fibrogenesis	fibrogenesis	NN
cord-257662-viy65y72	283	16	.	.	.
cord-257662-viy65y72	284	1	MHV-68	mhv-68	CD
cord-257662-viy65y72	284	2	infection	infection	NN
cord-257662-viy65y72	284	3	in	in	IN
cord-257662-viy65y72	284	4	IFN	IFN	NNP
cord-257662-viy65y72	284	5	-	-	HYPH
cord-257662-viy65y72	284	6	γR	γR	NNP
cord-257662-viy65y72	285	1	−/−	−/−	NNP
cord-257662-viy65y72	285	2	mice	mouse	NNS
cord-257662-viy65y72	285	3	also	also	RB
cord-257662-viy65y72	285	4	resulted	result	VBD
cord-257662-viy65y72	285	5	in	in	IN
cord-257662-viy65y72	285	6	fibrosis	fibrosis	NN
cord-257662-viy65y72	285	7	in	in	IN
cord-257662-viy65y72	285	8	lymphoid	lymphoid	JJ
cord-257662-viy65y72	285	9	tissues	tissue	NNS
cord-257662-viy65y72	285	10	such	such	JJ
cord-257662-viy65y72	285	11	as	as	IN
cord-257662-viy65y72	285	12	the	the	DT
cord-257662-viy65y72	285	13	spleen	spleen	NN
cord-257662-viy65y72	285	14	,	,	,
cord-257662-viy65y72	285	15	which	which	WDT
cord-257662-viy65y72	285	16	is	be	VBZ
cord-257662-viy65y72	285	17	a	a	DT
cord-257662-viy65y72	285	18	site	site	NN
cord-257662-viy65y72	285	19	of	of	IN
cord-257662-viy65y72	285	20	latent	latent	JJ
cord-257662-viy65y72	285	21	MHV-68	MHV-68	NNP
cord-257662-viy65y72	285	22	infection	infection	NN
cord-257662-viy65y72	285	23	,	,	,
cord-257662-viy65y72	285	24	and	and	CC
cord-257662-viy65y72	285	25	the	the	DT
cord-257662-viy65y72	285	26	liver	liver	NN
cord-257662-viy65y72	285	27	(	(	-LRB-
cord-257662-viy65y72	285	28	62	62	CD
cord-257662-viy65y72	285	29	,	,	,
cord-257662-viy65y72	285	30	63	63	CD
cord-257662-viy65y72	285	31	)	)	-RRB-
cord-257662-viy65y72	285	32	.	.	.
cord-257662-viy65y72	286	1	Similar	similar	JJ
cord-257662-viy65y72	286	2	to	to	IN
cord-257662-viy65y72	286	3	the	the	DT
cord-257662-viy65y72	286	4	lung	lung	NN
cord-257662-viy65y72	286	5	,	,	,
cord-257662-viy65y72	286	6	MHV-68	MHV-68	NNP
cord-257662-viy65y72	286	7	infection	infection	NN
cord-257662-viy65y72	286	8	in	in	IN
cord-257662-viy65y72	286	9	the	the	DT
cord-257662-viy65y72	286	10	absence	absence	NN
cord-257662-viy65y72	286	11	of	of	IN
cord-257662-viy65y72	286	12	IFN	IFN	NNP
cord-257662-viy65y72	286	13	-	-	HYPH
cord-257662-viy65y72	286	14	γR	γR	NNP
cord-257662-viy65y72	286	15	signaling	signal	VBG
cord-257662-viy65y72	286	16	induced	induce	VBN
cord-257662-viy65y72	286	17	a	a	DT
cord-257662-viy65y72	286	18	M2	m2	JJ
cord-257662-viy65y72	286	19	macrophage	macrophage	NN
cord-257662-viy65y72	286	20	response	response	NN
cord-257662-viy65y72	286	21	in	in	IN
cord-257662-viy65y72	286	22	the	the	DT
cord-257662-viy65y72	286	23	spleen	spleen	NN
cord-257662-viy65y72	286	24	,	,	,
cord-257662-viy65y72	286	25	characterized	characterize	VBN
cord-257662-viy65y72	286	26	by	by	IN
cord-257662-viy65y72	286	27	high	high	JJ
cord-257662-viy65y72	286	28	Arg1	arg1	JJ
cord-257662-viy65y72	286	29	expression	expression	NN
cord-257662-viy65y72	286	30	along	along	IN
cord-257662-viy65y72	286	31	with	with	IN
cord-257662-viy65y72	286	32	FIZZ1	FIZZ1	NNP
cord-257662-viy65y72	286	33	and	and	CC
cord-257662-viy65y72	286	34	M2	M2	NNP
cord-257662-viy65y72	286	35	/	/	SYM
cord-257662-viy65y72	286	36	Th2	th2	CD
cord-257662-viy65y72	286	37	cytokines	cytokine	NNS
cord-257662-viy65y72	286	38	such	such	JJ
cord-257662-viy65y72	286	39	as	as	IN
cord-257662-viy65y72	286	40	IL-13	IL-13	NNP
cord-257662-viy65y72	286	41	,	,	,
cord-257662-viy65y72	286	42	resulting	result	VBG
cord-257662-viy65y72	286	43	in	in	IN
cord-257662-viy65y72	286	44	fibrotic	fibrotic	JJ
cord-257662-viy65y72	286	45	disease	disease	NN
cord-257662-viy65y72	286	46	in	in	IN
cord-257662-viy65y72	286	47	the	the	DT
cord-257662-viy65y72	286	48	spleen	spleen	NN
cord-257662-viy65y72	286	49	(	(	-LRB-
cord-257662-viy65y72	286	50	105	105	CD
cord-257662-viy65y72	286	51	)	)	-RRB-
cord-257662-viy65y72	286	52	.	.	.
cord-257662-viy65y72	287	1	Moreover	moreover	RB
cord-257662-viy65y72	287	2	,	,	,
cord-257662-viy65y72	287	3	depletion	depletion	NN
cord-257662-viy65y72	287	4	of	of	IN
cord-257662-viy65y72	287	5	T	t	NN
cord-257662-viy65y72	287	6	cells	cell	NNS
cord-257662-viy65y72	287	7	prevented	prevent	VBD
cord-257662-viy65y72	287	8	MHV-68-mediated	mhv-68-mediated	JJ
cord-257662-viy65y72	287	9	fibrosis	fibrosis	NN
cord-257662-viy65y72	287	10	in	in	IN
cord-257662-viy65y72	287	11	IFN	IFN	NNP
cord-257662-viy65y72	287	12	-	-	HYPH
cord-257662-viy65y72	287	13	γR	γR	NNP
cord-257662-viy65y72	288	1	−/−	−/−	NNP
cord-257662-viy65y72	288	2	mice	mouse	NNS
cord-257662-viy65y72	288	3	(	(	-LRB-
cord-257662-viy65y72	288	4	62	62	CD
cord-257662-viy65y72	288	5	)	)	-RRB-
cord-257662-viy65y72	288	6	,	,	.
cord-257662-viy65y72	289	1	suggesting	suggest	VBG
cord-257662-viy65y72	289	2	that	that	IN
cord-257662-viy65y72	289	3	M2	M2	NNP
cord-257662-viy65y72	289	4	macrophages	macrophage	NNS
cord-257662-viy65y72	289	5	were	be	VBD
cord-257662-viy65y72	289	6	further	further	RB
cord-257662-viy65y72	289	7	driving	drive	VBG
cord-257662-viy65y72	289	8	Th2	th2	CD
cord-257662-viy65y72	289	9	activation	activation	NN
cord-257662-viy65y72	289	10	to	to	TO
cord-257662-viy65y72	289	11	possibly	possibly	RB
cord-257662-viy65y72	289	12	create	create	VB
cord-257662-viy65y72	289	13	a	a	DT
cord-257662-viy65y72	289	14	M2	M2	NNP
cord-257662-viy65y72	289	15	/	/	SYM
cord-257662-viy65y72	289	16	Th2	th2	CD
cord-257662-viy65y72	289	17	cytokine	cytokine	NN
cord-257662-viy65y72	289	18	-	-	HYPH
cord-257662-viy65y72	289	19	induced	induce	VBN
cord-257662-viy65y72	289	20	cycle	cycle	NN
cord-257662-viy65y72	289	21	,	,	,
cord-257662-viy65y72	289	22	resulting	result	VBG
cord-257662-viy65y72	289	23	in	in	IN
cord-257662-viy65y72	289	24	the	the	DT
cord-257662-viy65y72	289	25	exaggerated	exaggerated	JJ
cord-257662-viy65y72	289	26	pathology	pathology	NN
cord-257662-viy65y72	289	27	.	.	.
cord-257662-viy65y72	290	1	In	in	IN
cord-257662-viy65y72	290	2	contrast	contrast	NN
cord-257662-viy65y72	290	3	to	to	IN
cord-257662-viy65y72	290	4	IFN	IFN	NNP
cord-257662-viy65y72	290	5	-	-	HYPH
cord-257662-viy65y72	290	6	γR	γR	NNP
cord-257662-viy65y72	291	1	−/−	−/−	NNP
cord-257662-viy65y72	291	2	mice	mouse	NNS
cord-257662-viy65y72	291	3	,	,	,
cord-257662-viy65y72	291	4	iNOS	inos	JJ
cord-257662-viy65y72	291	5	was	be	VBD
cord-257662-viy65y72	291	6	induced	induce	VBN
cord-257662-viy65y72	291	7	in	in	IN
cord-257662-viy65y72	291	8	the	the	DT
cord-257662-viy65y72	291	9	spleen	spleen	NN
cord-257662-viy65y72	291	10	of	of	IN
cord-257662-viy65y72	291	11	MHV-68-infected	mhv-68-infected	JJ
cord-257662-viy65y72	291	12	WT	WT	NNP
cord-257662-viy65y72	291	13	mice	mouse	NNS
cord-257662-viy65y72	291	14	(	(	-LRB-
cord-257662-viy65y72	291	15	105	105	CD
cord-257662-viy65y72	291	16	)	)	-RRB-
cord-257662-viy65y72	291	17	,	,	,
cord-257662-viy65y72	291	18	indicating	indicate	VBG
cord-257662-viy65y72	291	19	an	an	DT
cord-257662-viy65y72	291	20	important	important	JJ
cord-257662-viy65y72	291	21	role	role	NN
cord-257662-viy65y72	291	22	for	for	IN
cord-257662-viy65y72	291	23	IFN	IFN	NNP
cord-257662-viy65y72	291	24	-	-	HYPH
cord-257662-viy65y72	291	25	γ	γ	NNP
cord-257662-viy65y72	291	26	in	in	IN
cord-257662-viy65y72	291	27	inducing	induce	VBG
cord-257662-viy65y72	291	28	a	a	DT
cord-257662-viy65y72	291	29	M1-associated	m1-associate	VBN
cord-257662-viy65y72	291	30	immune	immune	JJ
cord-257662-viy65y72	291	31	response	response	NN
cord-257662-viy65y72	291	32	to	to	TO
cord-257662-viy65y72	291	33	control	control	VB
cord-257662-viy65y72	291	34	gamma	gamma	NN
cord-257662-viy65y72	291	35	-	-	HYPH
cord-257662-viy65y72	291	36	herpesvirus	herpesvirus	NN
cord-257662-viy65y72	291	37	infection	infection	NN
cord-257662-viy65y72	291	38	and	and	CC
cord-257662-viy65y72	291	39	limiting	limit	VBG
cord-257662-viy65y72	291	40	Arg1-mediated	arg1-mediated	JJ
cord-257662-viy65y72	291	41	immunopathology	immunopathology	NN
cord-257662-viy65y72	291	42	.	.	.
cord-257662-viy65y72	292	1	Macrophages	macrophage	NNS
cord-257662-viy65y72	292	2	and	and	CC
cord-257662-viy65y72	292	3	other	other	JJ
cord-257662-viy65y72	292	4	myeloid	myeloid	NN
cord-257662-viy65y72	292	5	cells	cell	NNS
cord-257662-viy65y72	292	6	have	have	VBP
cord-257662-viy65y72	292	7	marked	mark	VBN
cord-257662-viy65y72	292	8	phenotypic	phenotypic	JJ
cord-257662-viy65y72	292	9	heterogeneity	heterogeneity	NN
cord-257662-viy65y72	292	10	,	,	,
cord-257662-viy65y72	292	11	as	as	IN
cord-257662-viy65y72	292	12	a	a	DT
cord-257662-viy65y72	292	13	result	result	NN
cord-257662-viy65y72	292	14	of	of	IN
cord-257662-viy65y72	292	15	distinct	distinct	JJ
cord-257662-viy65y72	292	16	cellular	cellular	JJ
cord-257662-viy65y72	292	17	differentiation	differentiation	NN
cord-257662-viy65y72	292	18	programs	program	NNS
cord-257662-viy65y72	292	19	,	,	,
cord-257662-viy65y72	292	20	distribution	distribution	NN
cord-257662-viy65y72	292	21	in	in	IN
cord-257662-viy65y72	292	22	tissues	tissue	NNS
cord-257662-viy65y72	292	23	,	,	,
cord-257662-viy65y72	292	24	and	and	CC
cord-257662-viy65y72	292	25	responsiveness	responsiveness	NN
cord-257662-viy65y72	292	26	to	to	IN
cord-257662-viy65y72	292	27	various	various	JJ
cord-257662-viy65y72	292	28	endogenous	endogenous	JJ
cord-257662-viy65y72	292	29	and	and	CC
cord-257662-viy65y72	292	30	exogenous	exogenous	JJ
cord-257662-viy65y72	292	31	stimuli	stimulus	NNS
cord-257662-viy65y72	292	32	.	.	.
cord-257662-viy65y72	293	1	Indeed	indeed	RB
cord-257662-viy65y72	293	2	,	,	,
cord-257662-viy65y72	293	3	macrophages	macrophage	NNS
cord-257662-viy65y72	293	4	have	have	VBP
cord-257662-viy65y72	293	5	well	well	RB
cord-257662-viy65y72	293	6	-	-	HYPH
cord-257662-viy65y72	293	7	established	establish	VBN
cord-257662-viy65y72	293	8	roles	role	NNS
cord-257662-viy65y72	293	9	in	in	IN
cord-257662-viy65y72	293	10	development	development	NN
cord-257662-viy65y72	293	11	,	,	,
cord-257662-viy65y72	293	12	tissue	tissue	NN
cord-257662-viy65y72	293	13	homeostasis	homeostasis	NN
cord-257662-viy65y72	293	14	,	,	,
cord-257662-viy65y72	293	15	coordinating	coordinate	VBG
cord-257662-viy65y72	293	16	the	the	DT
cord-257662-viy65y72	293	17	adaptive	adaptive	JJ
cord-257662-viy65y72	293	18	immune	immune	JJ
cord-257662-viy65y72	293	19	response	response	NN
cord-257662-viy65y72	293	20	and	and	CC
cord-257662-viy65y72	293	21	inflammation	inflammation	NN
cord-257662-viy65y72	293	22	,	,	,
cord-257662-viy65y72	293	23	as	as	RB
cord-257662-viy65y72	293	24	well	well	RB
cord-257662-viy65y72	293	25	as	as	IN
cord-257662-viy65y72	293	26	directing	direct	VBG
cord-257662-viy65y72	293	27	tissue	tissue	NN
cord-257662-viy65y72	293	28	resolution	resolution	NN
cord-257662-viy65y72	293	29	and	and	CC
cord-257662-viy65y72	293	30	repair	repair	NN
cord-257662-viy65y72	293	31	following	follow	VBG
cord-257662-viy65y72	293	32	damage	damage	NN
cord-257662-viy65y72	293	33	-processes	-processe	NNS
cord-257662-viy65y72	293	34	that	that	WDT
cord-257662-viy65y72	293	35	are	be	VBP
cord-257662-viy65y72	293	36	often	often	RB
cord-257662-viy65y72	293	37	modulated	modulate	VBN
cord-257662-viy65y72	293	38	via	via	IN
cord-257662-viy65y72	293	39	the	the	DT
cord-257662-viy65y72	293	40	actions	action	NNS
cord-257662-viy65y72	293	41	of	of	IN
cord-257662-viy65y72	293	42	the	the	DT
cord-257662-viy65y72	293	43	arginine	arginine	NN
cord-257662-viy65y72	293	44	-	-	HYPH
cord-257662-viy65y72	293	45	hydrolyzing	hydrolyzing	NN
cord-257662-viy65y72	293	46	enzymes	enzyme	NNS
cord-257662-viy65y72	293	47	Nos2	Nos2	NNP
cord-257662-viy65y72	293	48	and	and	CC
cord-257662-viy65y72	293	49	Arg1	Arg1	NNP
cord-257662-viy65y72	293	50	.	.	.
cord-257662-viy65y72	294	1	We	-PRON-	PRP
cord-257662-viy65y72	294	2	have	have	VBP
cord-257662-viy65y72	294	3	highlighted	highlight	VBN
cord-257662-viy65y72	294	4	a	a	DT
cord-257662-viy65y72	294	5	number	number	NN
cord-257662-viy65y72	294	6	of	of	IN
cord-257662-viy65y72	294	7	viral	viral	JJ
cord-257662-viy65y72	294	8	infections	infection	NNS
cord-257662-viy65y72	294	9	in	in	IN
cord-257662-viy65y72	294	10	which	which	WDT
cord-257662-viy65y72	294	11	these	these	DT
cord-257662-viy65y72	294	12	enzymes	enzyme	NNS
cord-257662-viy65y72	294	13	have	have	VBP
cord-257662-viy65y72	294	14	a	a	DT
cord-257662-viy65y72	294	15	beneficial	beneficial	JJ
cord-257662-viy65y72	294	16	effect	effect	NN
cord-257662-viy65y72	294	17	:	:	:
cord-257662-viy65y72	294	18	NO	no	DT
cord-257662-viy65y72	294	19	has	have	VBZ
cord-257662-viy65y72	294	20	antiviral	antiviral	JJ
cord-257662-viy65y72	294	21	properties	property	NNS
cord-257662-viy65y72	294	22	against	against	IN
cord-257662-viy65y72	294	23	a	a	DT
cord-257662-viy65y72	294	24	variety	variety	NN
cord-257662-viy65y72	294	25	of	of	IN
cord-257662-viy65y72	294	26	viruses	virus	NNS
cord-257662-viy65y72	294	27	,	,	,
cord-257662-viy65y72	294	28	and	and	CC
cord-257662-viy65y72	294	29	arginase	arginase	NN
cord-257662-viy65y72	294	30	activity	activity	NN
cord-257662-viy65y72	294	31	can	can	MD
cord-257662-viy65y72	294	32	mediate	mediate	VB
cord-257662-viy65y72	294	33	tissue	tissue	NN
cord-257662-viy65y72	294	34	repair	repair	NN
cord-257662-viy65y72	294	35	and	and	CC
cord-257662-viy65y72	294	36	regeneration	regeneration	NN
cord-257662-viy65y72	294	37	following	follow	VBG
cord-257662-viy65y72	294	38	a	a	DT
cord-257662-viy65y72	294	39	viral	viral	JJ
cord-257662-viy65y72	294	40	insult	insult	NN
cord-257662-viy65y72	294	41	(	(	-LRB-
cord-257662-viy65y72	294	42	Table	table	NN
cord-257662-viy65y72	294	43	1	1	CD
cord-257662-viy65y72	294	44	)	)	-RRB-
cord-257662-viy65y72	294	45	.	.	.
cord-257662-viy65y72	295	1	However	however	RB
cord-257662-viy65y72	295	2	,	,	,
cord-257662-viy65y72	295	3	NO	no	DT
cord-257662-viy65y72	295	4	production	production	NN
cord-257662-viy65y72	295	5	can	can	MD
cord-257662-viy65y72	295	6	also	also	RB
cord-257662-viy65y72	295	7	result	result	VB
cord-257662-viy65y72	295	8	in	in	IN
cord-257662-viy65y72	295	9	immunopathology	immunopathology	NN
cord-257662-viy65y72	295	10	in	in	IN
cord-257662-viy65y72	295	11	some	some	DT
cord-257662-viy65y72	295	12	virus	virus	NN
cord-257662-viy65y72	295	13	infections	infection	NNS
cord-257662-viy65y72	295	14	,	,	,
cord-257662-viy65y72	295	15	and	and	CC
cord-257662-viy65y72	295	16	the	the	DT
cord-257662-viy65y72	295	17	suppressive	suppressive	JJ
cord-257662-viy65y72	295	18	functions	function	NNS
cord-257662-viy65y72	295	19	of	of	IN
cord-257662-viy65y72	295	20	Arg1-expressing	arg1-expresse	VBG
cord-257662-viy65y72	295	21	macrophages	macrophage	NNS
cord-257662-viy65y72	295	22	can	can	MD
cord-257662-viy65y72	295	23	promote	promote	VB
cord-257662-viy65y72	295	24	immunopathology	immunopathology	NN
cord-257662-viy65y72	295	25	.	.	.
cord-257662-viy65y72	296	1	Additionally	additionally	RB
cord-257662-viy65y72	296	2	,	,	,
cord-257662-viy65y72	296	3	some	some	DT
cord-257662-viy65y72	296	4	viruses	virus	NNS
cord-257662-viy65y72	296	5	have	have	VBP
cord-257662-viy65y72	296	6	exploited	exploit	VBN
cord-257662-viy65y72	296	7	the	the	DT
cord-257662-viy65y72	296	8	immune	immune	JJ
cord-257662-viy65y72	296	9	-	-	HYPH
cord-257662-viy65y72	296	10	suppressive	suppressive	JJ
cord-257662-viy65y72	296	11	properties	property	NNS
cord-257662-viy65y72	296	12	of	of	IN
cord-257662-viy65y72	296	13	iNOS	inos	CD
cord-257662-viy65y72	296	14	-	-	HYPH
cord-257662-viy65y72	296	15	and	and	CC
cord-257662-viy65y72	296	16	/	/	SYM
cord-257662-viy65y72	296	17	or	or	CC
cord-257662-viy65y72	296	18	Arg1-expressing	arg1-expresse	VBG
cord-257662-viy65y72	296	19	macrophages	macrophage	NNS
cord-257662-viy65y72	296	20	to	to	TO
cord-257662-viy65y72	296	21	evade	evade	VB
cord-257662-viy65y72	296	22	the	the	DT
cord-257662-viy65y72	296	23	immune	immune	JJ
cord-257662-viy65y72	296	24	response	response	NN
cord-257662-viy65y72	296	25	,	,	,
cord-257662-viy65y72	296	26	particularly	particularly	RB
cord-257662-viy65y72	296	27	the	the	DT
cord-257662-viy65y72	296	28	antiviral	antiviral	JJ
cord-257662-viy65y72	296	29	T	T	NNP
cord-257662-viy65y72	296	30	cell	cell	NN
cord-257662-viy65y72	296	31	response	response	NN
cord-257662-viy65y72	296	32	,	,	,
cord-257662-viy65y72	296	33	resulting	result	VBG
cord-257662-viy65y72	296	34	in	in	IN
cord-257662-viy65y72	296	35	chronic	chronic	JJ
cord-257662-viy65y72	296	36	viral	viral	JJ
cord-257662-viy65y72	296	37	infections	infection	NNS
cord-257662-viy65y72	296	38	.	.	.
cord-257662-viy65y72	297	1	Clearly	clearly	RB
cord-257662-viy65y72	297	2	,	,	,
cord-257662-viy65y72	297	3	iNOS	inos	CD
cord-257662-viy65y72	297	4	-	-	HYPH
cord-257662-viy65y72	297	5	and	and	CC
cord-257662-viy65y72	297	6	/	/	SYM
cord-257662-viy65y72	297	7	or	or	CC
cord-257662-viy65y72	297	8	Arg1-mediated	arg1-mediated	JJ
cord-257662-viy65y72	297	9	responses	response	NNS
cord-257662-viy65y72	297	10	are	be	VBP
cord-257662-viy65y72	297	11	important	important	JJ
cord-257662-viy65y72	297	12	in	in	IN
cord-257662-viy65y72	297	13	many	many	JJ
cord-257662-viy65y72	297	14	viral	viral	JJ
cord-257662-viy65y72	297	15	infections	infection	NNS
cord-257662-viy65y72	297	16	.	.	.
cord-257662-viy65y72	298	1	Thus	thus	RB
cord-257662-viy65y72	298	2	,	,	,
cord-257662-viy65y72	298	3	there	there	EX
cord-257662-viy65y72	298	4	is	be	VBZ
cord-257662-viy65y72	298	5	the	the	DT
cord-257662-viy65y72	298	6	potential	potential	NN
cord-257662-viy65y72	298	7	to	to	TO
cord-257662-viy65y72	298	8	develop	develop	VB
cord-257662-viy65y72	298	9	the	the	DT
cord-257662-viy65y72	298	10	means	mean	NNS
cord-257662-viy65y72	298	11	to	to	TO
cord-257662-viy65y72	298	12	selectively	selectively	RB
cord-257662-viy65y72	298	13	stimulate	stimulate	VB
cord-257662-viy65y72	298	14	or	or	CC
cord-257662-viy65y72	298	15	inhibit	inhibit	VB
cord-257662-viy65y72	298	16	either	either	CC
cord-257662-viy65y72	298	17	M1	M1	NNP
cord-257662-viy65y72	298	18	or	or	CC
cord-257662-viy65y72	298	19	M2	M2	NNP
cord-257662-viy65y72	298	20	responses	response	NNS
cord-257662-viy65y72	298	21	to	to	TO
cord-257662-viy65y72	298	22	mediate	mediate	VB
cord-257662-viy65y72	298	23	viral	viral	JJ
cord-257662-viy65y72	298	24	clearance	clearance	NN
cord-257662-viy65y72	298	25	or	or	CC
cord-257662-viy65y72	298	26	repair	repair	NN
cord-257662-viy65y72	298	27	tissue	tissue	NN
cord-257662-viy65y72	298	28	damage	damage	NN
cord-257662-viy65y72	298	29	.	.	.
cord-257662-viy65y72	299	1	Due	due	IN
cord-257662-viy65y72	299	2	to	to	IN
cord-257662-viy65y72	299	3	the	the	DT
cord-257662-viy65y72	299	4	overlap	overlap	NN
cord-257662-viy65y72	299	5	in	in	IN
cord-257662-viy65y72	299	6	immunosuppressive	immunosuppressive	JJ
cord-257662-viy65y72	299	7	mechanisms	mechanism	NNS
cord-257662-viy65y72	299	8	of	of	IN
cord-257662-viy65y72	299	9	iNOS	inos	CD
cord-257662-viy65y72	299	10	-	-	HYPH
cord-257662-viy65y72	299	11	and	and	CC
cord-257662-viy65y72	299	12	/	/	SYM
cord-257662-viy65y72	299	13	or	or	CC
cord-257662-viy65y72	299	14	Arg1-expressing	arg1-expresse	VBG
cord-257662-viy65y72	299	15	suppressor	suppressor	NN
cord-257662-viy65y72	299	16	cells	cell	NNS
cord-257662-viy65y72	299	17	,	,	,
cord-257662-viy65y72	299	18	therapeutic	therapeutic	JJ
cord-257662-viy65y72	299	19	strategies	strategy	NNS
cord-257662-viy65y72	299	20	under	under	IN
cord-257662-viy65y72	299	21	development	development	NN
cord-257662-viy65y72	299	22	to	to	TO
cord-257662-viy65y72	299	23	limit	limit	VB
cord-257662-viy65y72	299	24	the	the	DT
cord-257662-viy65y72	299	25	immunosuppressive	immunosuppressive	JJ
cord-257662-viy65y72	299	26	effects	effect	NNS
cord-257662-viy65y72	299	27	of	of	IN
cord-257662-viy65y72	299	28	myeloid	myeloid	NN
cord-257662-viy65y72	299	29	cells	cell	NNS
cord-257662-viy65y72	299	30	in	in	IN
cord-257662-viy65y72	299	31	cancer	cancer	NN
cord-257662-viy65y72	299	32	may	may	MD
cord-257662-viy65y72	299	33	be	be	VB
cord-257662-viy65y72	299	34	beneficial	beneficial	JJ
cord-257662-viy65y72	299	35	in	in	IN
cord-257662-viy65y72	299	36	treating	treat	VBG
cord-257662-viy65y72	299	37	persistent	persistent	JJ
cord-257662-viy65y72	299	38	/	/	SYM
cord-257662-viy65y72	299	39	chronic	chronic	JJ
cord-257662-viy65y72	299	40	virus	virus	NN
cord-257662-viy65y72	299	41	infections	infection	NNS
cord-257662-viy65y72	299	42	.	.	.
cord-257662-viy65y72	300	1	However	however	RB
cord-257662-viy65y72	300	2	,	,	,
cord-257662-viy65y72	300	3	as	as	IN
cord-257662-viy65y72	300	4	described	describe	VBN
cord-257662-viy65y72	300	5	above	above	RB
cord-257662-viy65y72	300	6	,	,	,
cord-257662-viy65y72	300	7	iNOS	inos	JJ
cord-257662-viy65y72	300	8	and	and	CC
cord-257662-viy65y72	300	9	Arg1	arg1	JJ
cord-257662-viy65y72	300	10	activity	activity	NN
cord-257662-viy65y72	300	11	can	can	MD
cord-257662-viy65y72	300	12	be	be	VB
cord-257662-viy65y72	300	13	both	both	DT
cord-257662-viy65y72	300	14	beneficial	beneficial	JJ
cord-257662-viy65y72	300	15	and	and	CC
cord-257662-viy65y72	300	16	detrimental	detrimental	JJ
cord-257662-viy65y72	300	17	during	during	IN
cord-257662-viy65y72	300	18	certain	certain	JJ
cord-257662-viy65y72	300	19	viral	viral	JJ
cord-257662-viy65y72	300	20	infections	infection	NNS
cord-257662-viy65y72	300	21	.	.	.
cord-257662-viy65y72	301	1	Therefore	therefore	RB
cord-257662-viy65y72	301	2	,	,	,
cord-257662-viy65y72	301	3	further	further	JJ
cord-257662-viy65y72	301	4	research	research	NN
cord-257662-viy65y72	301	5	is	be	VBZ
cord-257662-viy65y72	301	6	needed	need	VBN
cord-257662-viy65y72	301	7	to	to	TO
cord-257662-viy65y72	301	8	define	define	VB
cord-257662-viy65y72	301	9	the	the	DT
cord-257662-viy65y72	301	10	molecular	molecular	JJ
cord-257662-viy65y72	301	11	and	and	CC
cord-257662-viy65y72	301	12	tissue	tissue	NN
cord-257662-viy65y72	301	13	-	-	HYPH
cord-257662-viy65y72	301	14	specific	specific	JJ
cord-257662-viy65y72	301	15	mechanism(s	mechanism(s	NNP
cord-257662-viy65y72	301	16	)	)	-RRB-
cord-257662-viy65y72	301	17	by	by	IN
cord-257662-viy65y72	301	18	which	which	WDT
cord-257662-viy65y72	301	19	iNOS	iNOS	NNP
cord-257662-viy65y72	301	20	and	and	CC
cord-257662-viy65y72	301	21	Arg1	arg1	JJ
cord-257662-viy65y72	301	22	influence	influence	VBP
cord-257662-viy65y72	301	23	the	the	DT
cord-257662-viy65y72	301	24	clearance	clearance	NN
cord-257662-viy65y72	301	25	of	of	IN
cord-257662-viy65y72	301	26	viral	viral	JJ
cord-257662-viy65y72	301	27	pathogens	pathogen	NNS
cord-257662-viy65y72	301	28	as	as	RB
cord-257662-viy65y72	301	29	well	well	RB
cord-257662-viy65y72	301	30	as	as	IN
cord-257662-viy65y72	301	31	the	the	DT
cord-257662-viy65y72	301	32	injury	injury	NN
cord-257662-viy65y72	301	33	and	and	CC
cord-257662-viy65y72	301	34	repair	repair	NN
cord-257662-viy65y72	301	35	of	of	IN
cord-257662-viy65y72	301	36	tissues	tissue	NNS
cord-257662-viy65y72	301	37	.	.	.
cord-257662-viy65y72	302	1	In	in	IN
cord-257662-viy65y72	302	2	addition	addition	NN
cord-257662-viy65y72	302	3	,	,	,
cord-257662-viy65y72	302	4	a	a	DT
cord-257662-viy65y72	302	5	better	well	JJR
cord-257662-viy65y72	302	6	understanding	understanding	NN
cord-257662-viy65y72	302	7	of	of	IN
cord-257662-viy65y72	302	8	the	the	DT
cord-257662-viy65y72	302	9	pathways	pathway	NNS
cord-257662-viy65y72	302	10	regulating	regulate	VBG
cord-257662-viy65y72	302	11	macrophage	macrophage	NN
cord-257662-viy65y72	302	12	polarization	polarization	NN
cord-257662-viy65y72	302	13	(	(	-LRB-
cord-257662-viy65y72	302	14	specifically	specifically	RB
cord-257662-viy65y72	302	15	iNOS	inos	JJ
cord-257662-viy65y72	302	16	and/or	and/or	CC
cord-257662-viy65y72	302	17	Arg1	arg1	JJ
cord-257662-viy65y72	302	18	induction	induction	NN
cord-257662-viy65y72	302	19	and	and	CC
cord-257662-viy65y72	302	20	activity	activity	NN
cord-257662-viy65y72	302	21	)	)	-RRB-
cord-257662-viy65y72	302	22	,	,	,
cord-257662-viy65y72	302	23	macrophage	macrophage	NN
cord-257662-viy65y72	302	24	trafficking	trafficking	NN
cord-257662-viy65y72	302	25	,	,	,
cord-257662-viy65y72	302	26	and	and	CC
cord-257662-viy65y72	302	27	the	the	DT
cord-257662-viy65y72	302	28	precise	precise	JJ
cord-257662-viy65y72	302	29	effects	effect	NNS
cord-257662-viy65y72	302	30	of	of	IN
cord-257662-viy65y72	302	31	iNOS	inos	NN
cord-257662-viy65y72	302	32	and	and	CC
cord-257662-viy65y72	302	33	Arg1	arg1	JJ
cord-257662-viy65y72	302	34	activity	activity	NN
cord-257662-viy65y72	302	35	on	on	IN
cord-257662-viy65y72	302	36	other	other	JJ
cord-257662-viy65y72	302	37	immune	immune	JJ
cord-257662-viy65y72	302	38	cells	cell	NNS
cord-257662-viy65y72	302	39	following	follow	VBG
cord-257662-viy65y72	302	40	different	different	JJ
cord-257662-viy65y72	302	41	virus	virus	NN
cord-257662-viy65y72	302	42	infections	infection	NNS
cord-257662-viy65y72	302	43	will	will	MD
cord-257662-viy65y72	302	44	inform	inform	VB
cord-257662-viy65y72	302	45	the	the	DT
cord-257662-viy65y72	302	46	development	development	NN
cord-257662-viy65y72	302	47	of	of	IN
cord-257662-viy65y72	302	48	therapeutics	therapeutic	NNS
cord-257662-viy65y72	302	49	that	that	WDT
cord-257662-viy65y72	302	50	target	target	VBP
cord-257662-viy65y72	302	51	critical	critical	JJ
cord-257662-viy65y72	302	52	effector	effector	NN
cord-257662-viy65y72	302	53	molecules	molecule	NNS
cord-257662-viy65y72	302	54	to	to	TO
cord-257662-viy65y72	302	55	promote	promote	VB
cord-257662-viy65y72	302	56	viral	viral	JJ
cord-257662-viy65y72	302	57	control	control	NN
cord-257662-viy65y72	302	58	and	and	CC
cord-257662-viy65y72	302	59	limit	limit	VB
cord-257662-viy65y72	302	60	immunopathology	immunopathology	NN
cord-257662-viy65y72	302	61	.	.	.
cord-257662-viy65y72	303	1	Protective	protective	JJ
cord-257662-viy65y72	303	2	and	and	CC
cord-257662-viy65y72	303	3	pathogenic	pathogenic	JJ
cord-257662-viy65y72	303	4	functions	function	NNS
cord-257662-viy65y72	303	5	of	of	IN
cord-257662-viy65y72	303	6	macrophage	macrophage	NN
cord-257662-viy65y72	303	7	subsets	subset	NNS
cord-257662-viy65y72	303	8	M1	M1	NNP
cord-257662-viy65y72	303	9	and	and	CC
cord-257662-viy65y72	303	10	M2	M2	NNP
cord-257662-viy65y72	303	11	macrophages	macrophage	NNS
cord-257662-viy65y72	303	12	:	:	:
cord-257662-viy65y72	303	13	oracles	oracle	NNS
cord-257662-viy65y72	303	14	of	of	IN
cord-257662-viy65y72	303	15	health	health	NN
cord-257662-viy65y72	303	16	and	and	CC
cord-257662-viy65y72	303	17	disease	disease	NN
cord-257662-viy65y72	303	18	Arginase	Arginase	NNP
cord-257662-viy65y72	303	19	:	:	:
cord-257662-viy65y72	303	20	an	an	DT
cord-257662-viy65y72	303	21	emerging	emerge	VBG
cord-257662-viy65y72	303	22	key	key	JJ
cord-257662-viy65y72	303	23	player	player	NN
cord-257662-viy65y72	303	24	in	in	IN
cord-257662-viy65y72	303	25	the	the	DT
cord-257662-viy65y72	303	26	mammalian	mammalian	JJ
cord-257662-viy65y72	303	27	immune	immune	NN
cord-257662-viy65y72	303	28	system	system	NN
cord-257662-viy65y72	303	29	Coordinated	coordinate	VBD
cord-257662-viy65y72	303	30	regulation	regulation	NN
cord-257662-viy65y72	303	31	of	of	IN
cord-257662-viy65y72	303	32	myeloid	myeloid	NN
cord-257662-viy65y72	303	33	cells	cell	NNS
cord-257662-viy65y72	303	34	by	by	IN
cord-257662-viy65y72	303	35	tumours	tumour	NNS
cord-257662-viy65y72	303	36	Myeloid	Myeloid	NNP
cord-257662-viy65y72	303	37	derived	derive	VBD
cord-257662-viy65y72	303	38	suppressor	suppressor	NN
cord-257662-viy65y72	303	39	cells	cell	NNS
cord-257662-viy65y72	303	40	and	and	CC
cord-257662-viy65y72	303	41	their	-PRON-	PRP$
cord-257662-viy65y72	303	42	role	role	NN
cord-257662-viy65y72	303	43	in	in	IN
cord-257662-viy65y72	303	44	diseases	disease	NNS
cord-257662-viy65y72	303	45	Macrophage	Macrophage	NNP
cord-257662-viy65y72	303	46	activation	activation	NN
cord-257662-viy65y72	303	47	and	and	CC
cord-257662-viy65y72	303	48	polarization	polarization	NN
cord-257662-viy65y72	303	49	:	:	:
cord-257662-viy65y72	303	50	nomenclature	nomenclature	NN
cord-257662-viy65y72	303	51	and	and	CC
cord-257662-viy65y72	303	52	experimental	experimental	JJ
cord-257662-viy65y72	303	53	guidelines	guideline	NNS
cord-257662-viy65y72	303	54	Role	role	NN
cord-257662-viy65y72	303	55	of	of	IN
cord-257662-viy65y72	303	56	nitric	nitric	JJ
cord-257662-viy65y72	303	57	oxide	oxide	NN
cord-257662-viy65y72	303	58	synthesis	synthesis	NN
cord-257662-viy65y72	303	59	in	in	IN
cord-257662-viy65y72	303	60	macrophage	macrophage	NN
cord-257662-viy65y72	303	61	antimicrobial	antimicrobial	JJ
cord-257662-viy65y72	303	62	activity	activity	NN
cord-257662-viy65y72	303	63	Role	role	NN
cord-257662-viy65y72	303	64	of	of	IN
cord-257662-viy65y72	303	65	nitric	nitric	JJ
cord-257662-viy65y72	303	66	oxide	oxide	NN
cord-257662-viy65y72	303	67	in	in	IN
cord-257662-viy65y72	303	68	parasitic	parasitic	JJ
cord-257662-viy65y72	303	69	infections	infection	NNS
cord-257662-viy65y72	303	70	Inhibition	inhibition	NN
cord-257662-viy65y72	303	71	of	of	IN
cord-257662-viy65y72	303	72	viral	viral	JJ
cord-257662-viy65y72	303	73	replication	replication	NN
cord-257662-viy65y72	303	74	by	by	IN
cord-257662-viy65y72	303	75	interferon	interferon	NN
cord-257662-viy65y72	303	76	-	-	HYPH
cord-257662-viy65y72	303	77	gamma	gamma	NN
cord-257662-viy65y72	303	78	-	-	HYPH
cord-257662-viy65y72	303	79	induced	induce	VBN
cord-257662-viy65y72	303	80	nitric	nitric	NN
cord-257662-viy65y72	303	81	oxide	oxide	NN
cord-257662-viy65y72	303	82	synthase	synthase	NN
cord-257662-viy65y72	303	83	Evidence	evidence	NN
cord-257662-viy65y72	303	84	for	for	IN
cord-257662-viy65y72	303	85	antiviral	antiviral	JJ
cord-257662-viy65y72	303	86	effect	effect	NN
cord-257662-viy65y72	303	87	of	of	IN
cord-257662-viy65y72	303	88	nitric	nitric	JJ
cord-257662-viy65y72	303	89	oxide	oxide	NN
cord-257662-viy65y72	303	90	.	.	.
cord-257662-viy65y72	304	1	Inhibition	inhibition	NN
cord-257662-viy65y72	304	2	of	of	IN
cord-257662-viy65y72	304	3	herpes	herpes	NNP
cord-257662-viy65y72	304	4	simplex	simplex	NNP
cord-257662-viy65y72	304	5	virus	virus	NN
cord-257662-viy65y72	304	6	type	type	NN
cord-257662-viy65y72	304	7	1	1	CD
cord-257662-viy65y72	304	8	replication	replication	NN
cord-257662-viy65y72	304	9	Inhibition	inhibition	NN
cord-257662-viy65y72	304	10	of	of	IN
cord-257662-viy65y72	304	11	vesicular	vesicular	JJ
cord-257662-viy65y72	304	12	stomatitis	stomatitis	NN
cord-257662-viy65y72	304	13	virus	virus	NN
cord-257662-viy65y72	304	14	infection	infection	NN
cord-257662-viy65y72	304	15	by	by	IN
cord-257662-viy65y72	304	16	nitric	nitric	NN
cord-257662-viy65y72	304	17	oxide	oxide	NN
cord-257662-viy65y72	304	18	Inhibition	inhibition	NN
cord-257662-viy65y72	304	19	of	of	IN
cord-257662-viy65y72	304	20	Japanese	japanese	JJ
cord-257662-viy65y72	304	21	encephalitis	encephalitis	RB
cord-257662-viy65y72	304	22	virus	virus	NN
cord-257662-viy65y72	304	23	infection	infection	NN
cord-257662-viy65y72	304	24	by	by	IN
cord-257662-viy65y72	304	25	nitric	nitric	NN
cord-257662-viy65y72	304	26	oxide	oxide	NN
cord-257662-viy65y72	304	27	:	:	:
cord-257662-viy65y72	304	28	antiviral	antiviral	JJ
cord-257662-viy65y72	304	29	effect	effect	NN
cord-257662-viy65y72	304	30	of	of	IN
cord-257662-viy65y72	304	31	nitric	nitric	JJ
cord-257662-viy65y72	304	32	oxide	oxide	NN
cord-257662-viy65y72	304	33	on	on	IN
cord-257662-viy65y72	304	34	RNA	RNA	NNP
cord-257662-viy65y72	304	35	virus	virus	NN
cord-257662-viy65y72	304	36	replication	replication	NN
cord-257662-viy65y72	304	37	Inducible	Inducible	NNP
cord-257662-viy65y72	304	38	nitric	nitric	JJ
cord-257662-viy65y72	304	39	oxide	oxide	NN
cord-257662-viy65y72	304	40	synthase	synthase	NN
cord-257662-viy65y72	304	41	(	(	-LRB-
cord-257662-viy65y72	304	42	iNOS	inos	NN
cord-257662-viy65y72	304	43	)	)	-RRB-
cord-257662-viy65y72	304	44	expression	expression	NN
cord-257662-viy65y72	304	45	in	in	IN
cord-257662-viy65y72	304	46	monocytes	monocyte	NNS
cord-257662-viy65y72	304	47	during	during	IN
cord-257662-viy65y72	304	48	acute	acute	JJ
cord-257662-viy65y72	304	49	dengue	dengue	NN
cord-257662-viy65y72	304	50	fever	fever	NN
cord-257662-viy65y72	304	51	in	in	IN
cord-257662-viy65y72	304	52	patients	patient	NNS
cord-257662-viy65y72	304	53	and	and	CC
cord-257662-viy65y72	304	54	during	during	IN
cord-257662-viy65y72	304	55	in	in	IN
cord-257662-viy65y72	304	56	vitro	vitro	FW
cord-257662-viy65y72	304	57	infection	infection	NN
cord-257662-viy65y72	305	1	The	the	DT
cord-257662-viy65y72	305	2	role	role	NN
cord-257662-viy65y72	305	3	of	of	IN
cord-257662-viy65y72	305	4	inducible	inducible	JJ
cord-257662-viy65y72	305	5	nitric	nitric	NN
cord-257662-viy65y72	305	6	oxide	oxide	NN
cord-257662-viy65y72	305	7	synthase	synthase	NN
cord-257662-viy65y72	305	8	in	in	IN
cord-257662-viy65y72	305	9	the	the	DT
cord-257662-viy65y72	305	10	host	host	NN
cord-257662-viy65y72	305	11	response	response	NN
cord-257662-viy65y72	305	12	to	to	IN
cord-257662-viy65y72	305	13	coxsackievirus	coxsackievirus	NNP
cord-257662-viy65y72	305	14	myocarditis	myocarditis	NN
cord-257662-viy65y72	305	15	Inducible	Inducible	NNP
cord-257662-viy65y72	305	16	nitric	nitric	JJ
cord-257662-viy65y72	305	17	oxide	oxide	NN
cord-257662-viy65y72	305	18	synthase	synthase	NN
cord-257662-viy65y72	305	19	protection	protection	NN
cord-257662-viy65y72	305	20	against	against	IN
cord-257662-viy65y72	305	21	coxsackievirus	coxsackievirus	NNP
cord-257662-viy65y72	305	22	pancreatitis	pancreatitis	NNP
cord-257662-viy65y72	306	1	Sarvetnick	Sarvetnick	NNP
cord-257662-viy65y72	306	2	N.	N.	NNP
cord-257662-viy65y72	306	3	A	a	DT
cord-257662-viy65y72	306	4	critical	critical	JJ
cord-257662-viy65y72	306	5	role	role	NN
cord-257662-viy65y72	306	6	for	for	IN
cord-257662-viy65y72	306	7	inducible	inducible	JJ
cord-257662-viy65y72	306	8	nitric	nitric	JJ
cord-257662-viy65y72	306	9	oxide	oxide	NN
cord-257662-viy65y72	306	10	synthase	synthase	NN
cord-257662-viy65y72	306	11	in	in	IN
cord-257662-viy65y72	306	12	host	host	NN
cord-257662-viy65y72	306	13	survival	survival	NN
cord-257662-viy65y72	306	14	following	follow	VBG
cord-257662-viy65y72	306	15	coxsackievirus	coxsackievirus	NNP
cord-257662-viy65y72	306	16	B4	B4	NNP
cord-257662-viy65y72	306	17	infection	infection	NN
cord-257662-viy65y72	307	1	Nitric	nitric	NN
cord-257662-viy65y72	307	2	oxide	oxide	NN
cord-257662-viy65y72	307	3	inhibits	inhibit	VBZ
cord-257662-viy65y72	307	4	viral	viral	JJ
cord-257662-viy65y72	307	5	replication	replication	NN
cord-257662-viy65y72	307	6	in	in	IN
cord-257662-viy65y72	307	7	murine	murine	JJ
cord-257662-viy65y72	307	8	myocarditis	myocarditis	NN
cord-257662-viy65y72	307	9	Identification	identification	NN
cord-257662-viy65y72	307	10	of	of	IN
cord-257662-viy65y72	307	11	nitric	nitric	JJ
cord-257662-viy65y72	307	12	oxide	oxide	NN
cord-257662-viy65y72	307	13	synthase	synthase	NN
cord-257662-viy65y72	307	14	2	2	CD
cord-257662-viy65y72	307	15	as	as	IN
cord-257662-viy65y72	307	16	an	an	DT
cord-257662-viy65y72	307	17	innate	innate	JJ
cord-257662-viy65y72	307	18	resistance	resistance	NN
cord-257662-viy65y72	307	19	locus	locus	NN
cord-257662-viy65y72	307	20	against	against	IN
cord-257662-viy65y72	307	21	ectromelia	ectromelia	NNP
cord-257662-viy65y72	307	22	virus	virus	NNP
cord-257662-viy65y72	307	23	infection	infection	NN
cord-257662-viy65y72	307	24	Control	Control	NNP
cord-257662-viy65y72	307	25	of	of	IN
cord-257662-viy65y72	307	26	RSV	RSV	NNP
cord-257662-viy65y72	307	27	-	-	HYPH
cord-257662-viy65y72	307	28	induced	induce	VBN
cord-257662-viy65y72	307	29	lung	lung	NN
cord-257662-viy65y72	307	30	injury	injury	NN
cord-257662-viy65y72	307	31	by	by	IN
cord-257662-viy65y72	307	32	alternatively	alternatively	RB
cord-257662-viy65y72	307	33	activated	activate	VBN
cord-257662-viy65y72	307	34	macrophages	macrophage	NNS
cord-257662-viy65y72	307	35	is	be	VBZ
cord-257662-viy65y72	307	36	IL-4R	il-4r	CD
cord-257662-viy65y72	307	37	alpha-	alpha-	XX
cord-257662-viy65y72	307	38	,	,	,
cord-257662-viy65y72	308	1	TLR4-	tlr4-	NN
cord-257662-viy65y72	308	2	,	,	,
cord-257662-viy65y72	308	3	and	and	CC
cord-257662-viy65y72	309	1	IFN	IFN	NNP
cord-257662-viy65y72	309	2	-	-	HYPH
cord-257662-viy65y72	309	3	beta	beta	NN
cord-257662-viy65y72	309	4	-	-	HYPH
cord-257662-viy65y72	309	5	dependent	dependent	JJ
cord-257662-viy65y72	309	6	Role	role	NN
cord-257662-viy65y72	309	7	of	of	IN
cord-257662-viy65y72	309	8	the	the	DT
cord-257662-viy65y72	309	9	lipoxygenase	lipoxygenase	NN
cord-257662-viy65y72	309	10	pathway	pathway	NN
cord-257662-viy65y72	309	11	in	in	IN
cord-257662-viy65y72	309	12	RSV	RSV	NNP
cord-257662-viy65y72	309	13	-	-	HYPH
cord-257662-viy65y72	309	14	induced	induce	VBN
cord-257662-viy65y72	309	15	alternatively	alternatively	RB
cord-257662-viy65y72	309	16	activated	activate	VBD
cord-257662-viy65y72	309	17	macrophages	macrophage	NNS
cord-257662-viy65y72	309	18	leading	lead	VBG
cord-257662-viy65y72	309	19	to	to	IN
cord-257662-viy65y72	309	20	resolution	resolution	NN
cord-257662-viy65y72	309	21	of	of	IN
cord-257662-viy65y72	309	22	lung	lung	NN
cord-257662-viy65y72	309	23	pathology	pathology	NN
cord-257662-viy65y72	309	24	Agents	agent	NNS
cord-257662-viy65y72	309	25	that	that	WDT
cord-257662-viy65y72	309	26	increase	increase	VBP
cord-257662-viy65y72	309	27	AAM	AAM	NNP
cord-257662-viy65y72	309	28	differentiation	differentiation	NN
cord-257662-viy65y72	309	29	blunt	blunt	JJ
cord-257662-viy65y72	309	30	RSV	rsv	NN
cord-257662-viy65y72	309	31	-	-	HYPH
cord-257662-viy65y72	309	32	mediated	mediate	VBN
cord-257662-viy65y72	309	33	lung	lung	NN
cord-257662-viy65y72	309	34	pathology	pathology	NN
cord-257662-viy65y72	309	35	Macrophage	Macrophage	NNP
cord-257662-viy65y72	309	36	control	control	NN
cord-257662-viy65y72	309	37	of	of	IN
cord-257662-viy65y72	309	38	herpes	herpes	NNP
cord-257662-viy65y72	309	39	simplex	simplex	NNP
cord-257662-viy65y72	309	40	virus	virus	NN
cord-257662-viy65y72	309	41	type	type	NN
cord-257662-viy65y72	309	42	1	1	CD
cord-257662-viy65y72	309	43	replication	replication	NN
cord-257662-viy65y72	309	44	in	in	IN
cord-257662-viy65y72	309	45	the	the	DT
cord-257662-viy65y72	309	46	peripheral	peripheral	JJ
cord-257662-viy65y72	309	47	nervous	nervous	JJ
cord-257662-viy65y72	309	48	system	system	NN
cord-257662-viy65y72	309	49	IL-4	IL-4	NNP
cord-257662-viy65y72	309	50	and	and	CC
cord-257662-viy65y72	309	51	IL-10	IL-10	NNP
cord-257662-viy65y72	309	52	antagonize	antagonize	VB
cord-257662-viy65y72	309	53	IL-12-mediated	il-12-mediated	JJ
cord-257662-viy65y72	309	54	protection	protection	NN
cord-257662-viy65y72	309	55	against	against	IN
cord-257662-viy65y72	309	56	acute	acute	JJ
cord-257662-viy65y72	309	57	vaccinia	vaccinia	NN
cord-257662-viy65y72	309	58	virus	virus	NN
cord-257662-viy65y72	309	59	infection	infection	NN
cord-257662-viy65y72	309	60	with	with	IN
cord-257662-viy65y72	309	61	a	a	DT
cord-257662-viy65y72	309	62	limited	limited	JJ
cord-257662-viy65y72	309	63	role	role	NN
cord-257662-viy65y72	309	64	of	of	IN
cord-257662-viy65y72	309	65	IFN	IFN	NNP
cord-257662-viy65y72	309	66	-	-	HYPH
cord-257662-viy65y72	309	67	gamma	gamma	NN
cord-257662-viy65y72	309	68	and	and	CC
cord-257662-viy65y72	309	69	nitric	nitric	NN
cord-257662-viy65y72	309	70	oxide	oxide	NN
cord-257662-viy65y72	309	71	synthetase	synthetase	NN
cord-257662-viy65y72	309	72	2	2	CD
cord-257662-viy65y72	309	73	IFN	IFN	NNP
cord-257662-viy65y72	309	74	-	-	HYPH
cord-257662-viy65y72	309	75	alpha	alpha	NN
cord-257662-viy65y72	309	76	-	-	HYPH
cord-257662-viy65y72	309	77	driven	drive	VBN
cord-257662-viy65y72	309	78	CCL2	CCL2	NNP
cord-257662-viy65y72	309	79	production	production	NN
cord-257662-viy65y72	309	80	recruits	recruit	VBZ
cord-257662-viy65y72	309	81	inflammatory	inflammatory	JJ
cord-257662-viy65y72	309	82	monocytes	monocyte	NNS
cord-257662-viy65y72	309	83	to	to	IN
cord-257662-viy65y72	309	84	infection	infection	NN
cord-257662-viy65y72	309	85	site	site	NN
cord-257662-viy65y72	309	86	in	in	IN
cord-257662-viy65y72	309	87	mice	mouse	NNS
cord-257662-viy65y72	309	88	Defense	defense	NN
cord-257662-viy65y72	309	89	against	against	IN
cord-257662-viy65y72	309	90	HSV-1	HSV-1	NNP
cord-257662-viy65y72	309	91	in	in	IN
cord-257662-viy65y72	309	92	a	a	DT
cord-257662-viy65y72	309	93	murine	murine	JJ
cord-257662-viy65y72	309	94	model	model	NN
cord-257662-viy65y72	309	95	is	be	VBZ
cord-257662-viy65y72	309	96	mediated	mediate	VBN
cord-257662-viy65y72	309	97	by	by	IN
cord-257662-viy65y72	309	98	iNOS	inos	NN
cord-257662-viy65y72	309	99	and	and	CC
cord-257662-viy65y72	309	100	orchestrated	orchestrate	VBN
cord-257662-viy65y72	309	101	by	by	IN
cord-257662-viy65y72	309	102	the	the	DT
cord-257662-viy65y72	309	103	activation	activation	NN
cord-257662-viy65y72	309	104	of	of	IN
cord-257662-viy65y72	309	105	TLR2	TLR2	NNP
cord-257662-viy65y72	309	106	and	and	CC
cord-257662-viy65y72	309	107	TLR9	TLR9	NNP
cord-257662-viy65y72	309	108	in	in	IN
cord-257662-viy65y72	309	109	trigeminal	trigeminal	JJ
cord-257662-viy65y72	309	110	ganglia	ganglion	NNS
cord-257662-viy65y72	309	111	Mice	mouse	NNS
cord-257662-viy65y72	309	112	lacking	lack	VBG
cord-257662-viy65y72	310	1	inducible	inducible	JJ
cord-257662-viy65y72	310	2	nitric	nitric	JJ
cord-257662-viy65y72	310	3	-	-	HYPH
cord-257662-viy65y72	310	4	oxide	oxide	NN
cord-257662-viy65y72	310	5	synthase	synthase	NN
cord-257662-viy65y72	310	6	are	be	VBP
cord-257662-viy65y72	310	7	more	more	RBR
cord-257662-viy65y72	310	8	susceptible	susceptible	JJ
cord-257662-viy65y72	310	9	to	to	IN
cord-257662-viy65y72	310	10	herpes	herpes	NN
cord-257662-viy65y72	310	11	simplex	simplex	NNP
cord-257662-viy65y72	310	12	virus	virus	NN
cord-257662-viy65y72	310	13	infection	infection	NN
cord-257662-viy65y72	310	14	despite	despite	IN
cord-257662-viy65y72	310	15	enhanced	enhanced	JJ
cord-257662-viy65y72	310	16	Th1	th1	NN
cord-257662-viy65y72	310	17	cell	cell	NN
cord-257662-viy65y72	310	18	responses	response	NNS
cord-257662-viy65y72	310	19	Bacterial	bacterial	JJ
cord-257662-viy65y72	310	20	colonization	colonization	NN
cord-257662-viy65y72	310	21	dampens	dampen	VBZ
cord-257662-viy65y72	310	22	influenza	influenza	NN
cord-257662-viy65y72	310	23	-	-	HYPH
cord-257662-viy65y72	310	24	mediated	mediate	VBN
cord-257662-viy65y72	310	25	acute	acute	JJ
cord-257662-viy65y72	310	26	lung	lung	NN
cord-257662-viy65y72	310	27	injury	injury	NN
cord-257662-viy65y72	310	28	via	via	IN
cord-257662-viy65y72	310	29	induction	induction	NN
cord-257662-viy65y72	310	30	of	of	IN
cord-257662-viy65y72	310	31	M2	M2	NNP
cord-257662-viy65y72	310	32	alveolar	alveolar	NN
cord-257662-viy65y72	310	33	macrophages	macrophage	NNS
cord-257662-viy65y72	310	34	Role	role	NN
cord-257662-viy65y72	310	35	of	of	IN
cord-257662-viy65y72	310	36	IFN	IFN	NNP
cord-257662-viy65y72	310	37	-	-	HYPH
cord-257662-viy65y72	310	38	gamma	gamma	NN
cord-257662-viy65y72	310	39	-	-	HYPH
cord-257662-viy65y72	310	40	induced	induce	VBN
cord-257662-viy65y72	310	41	indoleamine	indoleamine	NN
cord-257662-viy65y72	310	42	2,3	2,3	CD
cord-257662-viy65y72	310	43	dioxygenase	dioxygenase	NN
cord-257662-viy65y72	310	44	and	and	CC
cord-257662-viy65y72	310	45	inducible	inducible	JJ
cord-257662-viy65y72	310	46	nitric	nitric	NN
cord-257662-viy65y72	310	47	oxide	oxide	NN
cord-257662-viy65y72	310	48	synthase	synthase	NN
cord-257662-viy65y72	310	49	in	in	IN
cord-257662-viy65y72	310	50	the	the	DT
cord-257662-viy65y72	310	51	replication	replication	NN
cord-257662-viy65y72	310	52	of	of	IN
cord-257662-viy65y72	310	53	human	human	JJ
cord-257662-viy65y72	310	54	cytomegalovirus	cytomegalovirus	NN
cord-257662-viy65y72	310	55	in	in	IN
cord-257662-viy65y72	310	56	retinal	retinal	JJ
cord-257662-viy65y72	310	57	pigment	pigment	NN
cord-257662-viy65y72	310	58	epithelial	epithelial	NN
cord-257662-viy65y72	310	59	cells	cell	NNS
cord-257662-viy65y72	310	60	Role	role	NN
cord-257662-viy65y72	310	61	of	of	IN
cord-257662-viy65y72	310	62	nitric	nitric	JJ
cord-257662-viy65y72	310	63	oxide	oxide	NN
cord-257662-viy65y72	310	64	synthase	synthase	NN
cord-257662-viy65y72	310	65	type	type	NN
cord-257662-viy65y72	310	66	2	2	CD
cord-257662-viy65y72	310	67	in	in	IN
cord-257662-viy65y72	310	68	acute	acute	JJ
cord-257662-viy65y72	310	69	infection	infection	NN
cord-257662-viy65y72	310	70	with	with	IN
cord-257662-viy65y72	310	71	murine	murine	JJ
cord-257662-viy65y72	310	72	cytomegalovirus	cytomegalovirus	NNP
cord-257662-viy65y72	310	73	Differential	Differential	NNP
cord-257662-viy65y72	310	74	macrophage	macrophage	NN
cord-257662-viy65y72	310	75	polarization	polarization	NN
cord-257662-viy65y72	310	76	in	in	IN
cord-257662-viy65y72	310	77	male	male	JJ
cord-257662-viy65y72	310	78	and	and	CC
cord-257662-viy65y72	310	79	female	female	JJ
cord-257662-viy65y72	310	80	BALB	BALB	NNP
cord-257662-viy65y72	310	81	/	/	SYM
cord-257662-viy65y72	310	82	c	c	NN
cord-257662-viy65y72	310	83	mice	mouse	NNS
cord-257662-viy65y72	310	84	infected	infect	VBN
cord-257662-viy65y72	310	85	with	with	IN
cord-257662-viy65y72	310	86	coxsackievirus	coxsackievirus	NNP
cord-257662-viy65y72	310	87	B3	B3	NNP
cord-257662-viy65y72	310	88	defines	define	VBZ
cord-257662-viy65y72	310	89	susceptibility	susceptibility	NN
cord-257662-viy65y72	310	90	to	to	IN
cord-257662-viy65y72	310	91	viral	viral	JJ
cord-257662-viy65y72	310	92	myocarditis	myocarditis	NN
cord-257662-viy65y72	310	93	Cross	cross	NN
cord-257662-viy65y72	310	94	-	-	NN
cord-257662-viy65y72	310	95	regulation	regulation	NN
cord-257662-viy65y72	310	96	of	of	IN
cord-257662-viy65y72	310	97	T	T	NNP
cord-257662-viy65y72	310	98	regulatory	regulatory	JJ
cord-257662-viy65y72	310	99	-	-	HYPH
cord-257662-viy65y72	310	100	cell	cell	NN
cord-257662-viy65y72	310	101	response	response	NN
cord-257662-viy65y72	310	102	after	after	IN
cord-257662-viy65y72	310	103	coxsackievirus	coxsackievirus	NNP
cord-257662-viy65y72	310	104	B3	B3	NNP
cord-257662-viy65y72	310	105	infection	infection	NN
cord-257662-viy65y72	310	106	by	by	IN
cord-257662-viy65y72	310	107	NKT	NKT	NNP
cord-257662-viy65y72	310	108	and	and	CC
cord-257662-viy65y72	310	109	gammadelta	gammadelta	NNP
cord-257662-viy65y72	310	110	T	T	NNP
cord-257662-viy65y72	310	111	cells	cell	NNS
cord-257662-viy65y72	310	112	in	in	IN
cord-257662-viy65y72	310	113	the	the	DT
cord-257662-viy65y72	310	114	mouse	mouse	NN
cord-257662-viy65y72	310	115	Gamma	Gamma	NNP
cord-257662-viy65y72	310	116	interferon	interferon	NN
cord-257662-viy65y72	310	117	-	-	HYPH
cord-257662-viy65y72	310	118	induced	induce	VBN
cord-257662-viy65y72	310	119	,	,	,
cord-257662-viy65y72	310	120	nitric	nitric	JJ
cord-257662-viy65y72	310	121	oxidemediated	oxidemediate	VBN
cord-257662-viy65y72	310	122	inhibition	inhibition	NN
cord-257662-viy65y72	310	123	of	of	IN
cord-257662-viy65y72	310	124	vaccinia	vaccinia	NN
cord-257662-viy65y72	310	125	virus	virus	NN
cord-257662-viy65y72	310	126	replication	replication	NN
cord-257662-viy65y72	310	127	Nitric	nitric	NN
cord-257662-viy65y72	310	128	oxide	oxide	NN
cord-257662-viy65y72	310	129	inhibits	inhibit	VBZ
cord-257662-viy65y72	310	130	Marek	Marek	NNP
cord-257662-viy65y72	310	131	's	's	POS
cord-257662-viy65y72	310	132	disease	disease	NN
cord-257662-viy65y72	310	133	virus	virus	NN
cord-257662-viy65y72	310	134	replication	replication	NN
cord-257662-viy65y72	310	135	but	but	CC
cord-257662-viy65y72	310	136	is	be	VBZ
cord-257662-viy65y72	310	137	not	not	RB
cord-257662-viy65y72	310	138	the	the	DT
cord-257662-viy65y72	310	139	single	single	JJ
cord-257662-viy65y72	310	140	decisive	decisive	JJ
cord-257662-viy65y72	310	141	factor	factor	NN
cord-257662-viy65y72	310	142	in	in	IN
cord-257662-viy65y72	310	143	interferongamma	interferongamma	NNP
cord-257662-viy65y72	310	144	-	-	HYPH
cord-257662-viy65y72	310	145	mediated	mediate	VBN
cord-257662-viy65y72	310	146	viral	viral	JJ
cord-257662-viy65y72	310	147	inhibition	inhibition	NN
cord-257662-viy65y72	310	148	Inhibitory	inhibitory	JJ
cord-257662-viy65y72	310	149	effects	effect	NNS
cord-257662-viy65y72	310	150	of	of	IN
cord-257662-viy65y72	310	151	nitric	nitric	NN
cord-257662-viy65y72	310	152	oxide	oxide	NN
cord-257662-viy65y72	310	153	and	and	CC
cord-257662-viy65y72	310	154	gamma	gamma	NN
cord-257662-viy65y72	310	155	interferon	interferon	NN
cord-257662-viy65y72	310	156	on	on	RP
cord-257662-viy65y72	310	157	in	in	IN
cord-257662-viy65y72	310	158	vitro	vitro	FW
cord-257662-viy65y72	310	159	and	and	CC
cord-257662-viy65y72	310	160	in	in	IN
cord-257662-viy65y72	310	161	vivo	vivo	NN
cord-257662-viy65y72	310	162	replication	replication	NN
cord-257662-viy65y72	310	163	of	of	IN
cord-257662-viy65y72	310	164	Marek	Marek	NNP
cord-257662-viy65y72	310	165	's	's	POS
cord-257662-viy65y72	310	166	disease	disease	NN
cord-257662-viy65y72	310	167	virus	virus	NN
cord-257662-viy65y72	310	168	Resistance	resistance	NN
cord-257662-viy65y72	310	169	and	and	CC
cord-257662-viy65y72	310	170	susceptibility	susceptibility	NN
cord-257662-viy65y72	310	171	to	to	IN
cord-257662-viy65y72	310	172	Marek	Marek	NNP
cord-257662-viy65y72	310	173	's	's	POS
cord-257662-viy65y72	310	174	disease	disease	NN
cord-257662-viy65y72	310	175	:	:	:
cord-257662-viy65y72	311	1	nitric	nitric	JJ
cord-257662-viy65y72	311	2	oxide	oxide	NN
cord-257662-viy65y72	311	3	synthase	synthase	NN
cord-257662-viy65y72	311	4	/	/	SYM
cord-257662-viy65y72	311	5	arginase	arginase	NN
cord-257662-viy65y72	312	1	activity	activity	NN
cord-257662-viy65y72	312	2	balance	balance	NN
cord-257662-viy65y72	313	1	Nitric	nitric	NN
cord-257662-viy65y72	313	2	oxide	oxide	NN
cord-257662-viy65y72	313	3	inhibits	inhibit	VBZ
cord-257662-viy65y72	313	4	hepatitis	hepatitis	NN
cord-257662-viy65y72	313	5	B	B	NNP
cord-257662-viy65y72	313	6	virus	virus	NN
cord-257662-viy65y72	313	7	replication	replication	NN
cord-257662-viy65y72	313	8	in	in	IN
cord-257662-viy65y72	313	9	the	the	DT
cord-257662-viy65y72	313	10	livers	liver	NNS
cord-257662-viy65y72	313	11	of	of	IN
cord-257662-viy65y72	313	12	transgenic	transgenic	JJ
cord-257662-viy65y72	313	13	mice	mouse	NNS
cord-257662-viy65y72	313	14	Short	Short	NNP
cord-257662-viy65y72	313	15	report	report	NN
cord-257662-viy65y72	313	16	:	:	:
cord-257662-viy65y72	313	17	increased	increase	VBN
cord-257662-viy65y72	313	18	level	level	NN
cord-257662-viy65y72	313	19	of	of	IN
cord-257662-viy65y72	313	20	serum	serum	NN
cord-257662-viy65y72	313	21	nitric	nitric	NN
cord-257662-viy65y72	313	22	oxide	oxide	NN
cord-257662-viy65y72	313	23	in	in	IN
cord-257662-viy65y72	313	24	patients	patient	NNS
cord-257662-viy65y72	313	25	with	with	IN
cord-257662-viy65y72	313	26	dengue	dengue	NN
cord-257662-viy65y72	313	27	IFNgamma	ifngamma	IN
cord-257662-viy65y72	313	28	production	production	NN
cord-257662-viy65y72	313	29	depends	depend	VBZ
cord-257662-viy65y72	313	30	on	on	IN
cord-257662-viy65y72	313	31	IL-12	IL-12	NNP
cord-257662-viy65y72	313	32	and	and	CC
cord-257662-viy65y72	313	33	IL-18	IL-18	NNP
cord-257662-viy65y72	313	34	combined	combine	VBD
cord-257662-viy65y72	313	35	action	action	NN
cord-257662-viy65y72	313	36	and	and	CC
cord-257662-viy65y72	313	37	mediates	mediate	VBZ
cord-257662-viy65y72	313	38	host	host	NN
cord-257662-viy65y72	313	39	resistance	resistance	NN
cord-257662-viy65y72	313	40	to	to	IN
cord-257662-viy65y72	313	41	dengue	dengue	NN
cord-257662-viy65y72	313	42	virus	virus	NN
cord-257662-viy65y72	313	43	infection	infection	NN
cord-257662-viy65y72	313	44	in	in	IN
cord-257662-viy65y72	313	45	a	a	DT
cord-257662-viy65y72	313	46	nitric	nitric	JJ
cord-257662-viy65y72	313	47	oxide	oxide	NN
cord-257662-viy65y72	313	48	-	-	HYPH
cord-257662-viy65y72	313	49	dependent	dependent	JJ
cord-257662-viy65y72	313	50	manner	manner	NN
cord-257662-viy65y72	313	51	A	a	DT
cord-257662-viy65y72	313	52	model	model	NN
cord-257662-viy65y72	313	53	of	of	IN
cord-257662-viy65y72	313	54	DENV-3	denv-3	NN
cord-257662-viy65y72	313	55	infection	infection	NN
cord-257662-viy65y72	313	56	that	that	WDT
cord-257662-viy65y72	313	57	recapitulates	recapitulate	VBZ
cord-257662-viy65y72	313	58	severe	severe	JJ
cord-257662-viy65y72	313	59	disease	disease	NN
cord-257662-viy65y72	313	60	and	and	CC
cord-257662-viy65y72	313	61	highlights	highlight	VBZ
cord-257662-viy65y72	313	62	the	the	DT
cord-257662-viy65y72	313	63	importance	importance	NN
cord-257662-viy65y72	313	64	of	of	IN
cord-257662-viy65y72	313	65	IFN	IFN	NNP
cord-257662-viy65y72	313	66	-	-	HYPH
cord-257662-viy65y72	313	67	gamma	gamma	NNP
cord-257662-viy65y72	313	68	in	in	IN
cord-257662-viy65y72	313	69	host	host	NN
cord-257662-viy65y72	313	70	resistance	resistance	NN
cord-257662-viy65y72	313	71	to	to	IN
cord-257662-viy65y72	313	72	infection	infection	NN
cord-257662-viy65y72	313	73	Dengue	dengue	NN
cord-257662-viy65y72	313	74	fever	fever	NN
cord-257662-viy65y72	313	75	activates	activate	VBZ
cord-257662-viy65y72	313	76	the	the	DT
cord-257662-viy65y72	313	77	l	l	NN
cord-257662-viy65y72	313	78	-	-	HYPH
cord-257662-viy65y72	313	79	arginine	arginine	NN
cord-257662-viy65y72	313	80	-	-	HYPH
cord-257662-viy65y72	313	81	nitric	nitric	NN
cord-257662-viy65y72	313	82	oxide	oxide	NN
cord-257662-viy65y72	313	83	pathway	pathway	NN
cord-257662-viy65y72	313	84	:	:	:
cord-257662-viy65y72	313	85	an	an	DT
cord-257662-viy65y72	313	86	explanation	explanation	NN
cord-257662-viy65y72	313	87	for	for	IN
cord-257662-viy65y72	313	88	reduced	reduced	JJ
cord-257662-viy65y72	313	89	aggregation	aggregation	NN
cord-257662-viy65y72	313	90	of	of	IN
cord-257662-viy65y72	313	91	human	human	JJ
cord-257662-viy65y72	313	92	platelets	platelet	NNS
cord-257662-viy65y72	314	1	The	the	DT
cord-257662-viy65y72	314	2	l	l	NN
cord-257662-viy65y72	314	3	-	-	HYPH
cord-257662-viy65y72	314	4	arginine	arginine	NN
cord-257662-viy65y72	314	5	-	-	HYPH
cord-257662-viy65y72	314	6	nitric	nitric	NN
cord-257662-viy65y72	314	7	oxide	oxide	NN
cord-257662-viy65y72	314	8	pathway	pathway	NN
cord-257662-viy65y72	314	9	:	:	:
cord-257662-viy65y72	315	1	a	a	DT
cord-257662-viy65y72	315	2	potential	potential	JJ
cord-257662-viy65y72	315	3	therapeutic	therapeutic	JJ
cord-257662-viy65y72	315	4	target	target	NN
cord-257662-viy65y72	315	5	in	in	IN
cord-257662-viy65y72	315	6	dengue	dengue	NN
cord-257662-viy65y72	315	7	haemorrhagic	haemorrhagic	JJ
cord-257662-viy65y72	315	8	fever	fever	NN
cord-257662-viy65y72	315	9	Targeted	target	VBN
cord-257662-viy65y72	315	10	blockade	blockade	NN
cord-257662-viy65y72	315	11	in	in	IN
cord-257662-viy65y72	315	12	lethal	lethal	JJ
cord-257662-viy65y72	315	13	West	West	NNP
cord-257662-viy65y72	315	14	Nile	Nile	NNP
cord-257662-viy65y72	315	15	virus	virus	NN
cord-257662-viy65y72	315	16	encephalitis	encephalitis	RB
cord-257662-viy65y72	315	17	indicates	indicate	VBZ
cord-257662-viy65y72	315	18	a	a	DT
cord-257662-viy65y72	315	19	crucial	crucial	JJ
cord-257662-viy65y72	315	20	role	role	NN
cord-257662-viy65y72	315	21	for	for	IN
cord-257662-viy65y72	315	22	very	very	RB
cord-257662-viy65y72	315	23	late	late	JJ
cord-257662-viy65y72	315	24	antigen	antigen	NN
cord-257662-viy65y72	315	25	(	(	-LRB-
cord-257662-viy65y72	316	1	VLA)-4-dependent	vla)-4-dependent	NN
cord-257662-viy65y72	316	2	recruitment	recruitment	NN
cord-257662-viy65y72	316	3	of	of	IN
cord-257662-viy65y72	316	4	nitric	nitric	JJ
cord-257662-viy65y72	316	5	oxide	oxide	NN
cord-257662-viy65y72	316	6	-	-	HYPH
cord-257662-viy65y72	316	7	producing	produce	VBG
cord-257662-viy65y72	316	8	macrophages	macrophage	NNS
cord-257662-viy65y72	316	9	Inhibition	inhibition	NN
cord-257662-viy65y72	316	10	of	of	IN
cord-257662-viy65y72	316	11	nitric	nitric	JJ
cord-257662-viy65y72	316	12	oxide	oxide	NN
cord-257662-viy65y72	316	13	synthesis	synthesis	NN
cord-257662-viy65y72	316	14	increases	increase	NNS
cord-257662-viy65y72	316	15	mortality	mortality	NN
cord-257662-viy65y72	316	16	in	in	IN
cord-257662-viy65y72	316	17	Sindbis	Sindbis	NNP
cord-257662-viy65y72	316	18	virus	virus	NN
cord-257662-viy65y72	316	19	encephalitis	encephalitis	RB
cord-257662-viy65y72	316	20	Reovirus	Reovirus	NNP
cord-257662-viy65y72	316	21	infection	infection	NN
cord-257662-viy65y72	316	22	of	of	IN
cord-257662-viy65y72	316	23	the	the	DT
cord-257662-viy65y72	316	24	CNS	CNS	NNP
cord-257662-viy65y72	316	25	enhances	enhance	VBZ
cord-257662-viy65y72	316	26	iNOS	inos	JJ
cord-257662-viy65y72	316	27	expression	expression	NN
cord-257662-viy65y72	316	28	in	in	IN
cord-257662-viy65y72	316	29	areas	area	NNS
cord-257662-viy65y72	316	30	of	of	IN
cord-257662-viy65y72	316	31	virus	virus	NN
cord-257662-viy65y72	316	32	-	-	HYPH
cord-257662-viy65y72	316	33	induced	induce	VBN
cord-257662-viy65y72	316	34	injury	injury	NN
cord-257662-viy65y72	316	35	Inhibition	inhibition	NN
cord-257662-viy65y72	316	36	of	of	IN
cord-257662-viy65y72	316	37	influenza	influenza	NN
cord-257662-viy65y72	316	38	virus	virus	NN
cord-257662-viy65y72	316	39	replication	replication	NN
cord-257662-viy65y72	316	40	by	by	IN
cord-257662-viy65y72	316	41	nitric	nitric	NN
cord-257662-viy65y72	316	42	oxide	oxide	NN
cord-257662-viy65y72	317	1	Inhaled	inhale	VBN
cord-257662-viy65y72	317	2	nitric	nitric	NN
cord-257662-viy65y72	317	3	oxide	oxide	NN
cord-257662-viy65y72	317	4	therapy	therapy	NN
cord-257662-viy65y72	317	5	fails	fail	VBZ
cord-257662-viy65y72	317	6	to	to	TO
cord-257662-viy65y72	317	7	improve	improve	VB
cord-257662-viy65y72	317	8	outcome	outcome	NN
cord-257662-viy65y72	317	9	in	in	IN
cord-257662-viy65y72	317	10	experimental	experimental	JJ
cord-257662-viy65y72	317	11	severe	severe	JJ
cord-257662-viy65y72	317	12	influenza	influenza	NN
cord-257662-viy65y72	317	13	Increased	increase	VBD
cord-257662-viy65y72	317	14	inducible	inducible	JJ
cord-257662-viy65y72	317	15	nitric	nitric	NN
cord-257662-viy65y72	317	16	oxide	oxide	NN
cord-257662-viy65y72	317	17	synthase	synthase	NN
cord-257662-viy65y72	317	18	expression	expression	NN
cord-257662-viy65y72	317	19	in	in	IN
cord-257662-viy65y72	317	20	organs	organ	NNS
cord-257662-viy65y72	317	21	is	be	VBZ
cord-257662-viy65y72	317	22	associated	associate	VBN
cord-257662-viy65y72	317	23	with	with	IN
cord-257662-viy65y72	317	24	a	a	DT
cord-257662-viy65y72	317	25	higher	high	JJR
cord-257662-viy65y72	317	26	severity	severity	NN
cord-257662-viy65y72	317	27	of	of	IN
cord-257662-viy65y72	317	28	H5N1	H5N1	NNP
cord-257662-viy65y72	317	29	influenza	influenza	NN
cord-257662-viy65y72	317	30	virus	virus	NN
cord-257662-viy65y72	317	31	infection	infection	NN
cord-257662-viy65y72	317	32	Pathogenesis	Pathogenesis	NNP
cord-257662-viy65y72	317	33	of	of	IN
cord-257662-viy65y72	317	34	influenza	influenza	NN
cord-257662-viy65y72	317	35	virus	virus	NN
cord-257662-viy65y72	317	36	-	-	HYPH
cord-257662-viy65y72	317	37	induced	induce	VBN
cord-257662-viy65y72	317	38	pneumonia	pneumonia	NN
cord-257662-viy65y72	317	39	:	:	:
cord-257662-viy65y72	317	40	involvement	involvement	NN
cord-257662-viy65y72	317	41	of	of	IN
cord-257662-viy65y72	317	42	both	both	CC
cord-257662-viy65y72	317	43	nitric	nitric	JJ
cord-257662-viy65y72	317	44	oxide	oxide	NN
cord-257662-viy65y72	317	45	and	and	CC
cord-257662-viy65y72	317	46	oxygen	oxygen	NN
cord-257662-viy65y72	317	47	radicals	radical	NNS
cord-257662-viy65y72	318	1	Rapid	rapid	JJ
cord-257662-viy65y72	319	1	interferon	interferon	NNP
cord-257662-viy65y72	319	2	gamma	gamma	NN
cord-257662-viy65y72	319	3	-	-	HYPH
cord-257662-viy65y72	319	4	dependent	dependent	JJ
cord-257662-viy65y72	319	5	clearance	clearance	NN
cord-257662-viy65y72	319	6	of	of	IN
cord-257662-viy65y72	319	7	influenza	influenza	NN
cord-257662-viy65y72	319	8	A	a	DT
cord-257662-viy65y72	319	9	virus	virus	NN
cord-257662-viy65y72	319	10	and	and	CC
cord-257662-viy65y72	319	11	protection	protection	NN
cord-257662-viy65y72	319	12	from	from	IN
cord-257662-viy65y72	319	13	consolidating	consolidate	VBG
cord-257662-viy65y72	319	14	pneumonitis	pneumonitis	NN
cord-257662-viy65y72	319	15	in	in	IN
cord-257662-viy65y72	319	16	nitric	nitric	NN
cord-257662-viy65y72	319	17	oxide	oxide	NN
cord-257662-viy65y72	320	1	synthase	synthase	NN
cord-257662-viy65y72	320	2	2-deficient	2-deficient	CD
cord-257662-viy65y72	320	3	mice	mouse	NNS
cord-257662-viy65y72	321	1	Enhanced	enhanced	JJ
cord-257662-viy65y72	321	2	antiviral	antiviral	JJ
cord-257662-viy65y72	321	3	antibody	antibody	NN
cord-257662-viy65y72	321	4	secretion	secretion	NN
cord-257662-viy65y72	321	5	and	and	CC
cord-257662-viy65y72	321	6	attenuated	attenuated	JJ
cord-257662-viy65y72	321	7	immunopathology	immunopathology	NN
cord-257662-viy65y72	321	8	during	during	IN
cord-257662-viy65y72	321	9	influenza	influenza	NN
cord-257662-viy65y72	321	10	virus	virus	NN
cord-257662-viy65y72	321	11	infection	infection	NN
cord-257662-viy65y72	321	12	in	in	IN
cord-257662-viy65y72	321	13	nitric	nitric	NN
cord-257662-viy65y72	321	14	oxide	oxide	NN
cord-257662-viy65y72	321	15	synthase-2-deficient	synthase-2-deficient	NN
cord-257662-viy65y72	321	16	mice	mouse	NNS
cord-257662-viy65y72	322	1	Inducible	inducible	JJ
cord-257662-viy65y72	322	2	nitric	nitric	JJ
cord-257662-viy65y72	322	3	oxide	oxide	NN
cord-257662-viy65y72	322	4	contributes	contribute	VBZ
cord-257662-viy65y72	322	5	to	to	IN
cord-257662-viy65y72	322	6	viral	viral	JJ
cord-257662-viy65y72	322	7	pathogenesis	pathogenesis	NN
cord-257662-viy65y72	322	8	following	follow	VBG
cord-257662-viy65y72	322	9	highly	highly	RB
cord-257662-viy65y72	322	10	pathogenic	pathogenic	JJ
cord-257662-viy65y72	322	11	influenza	influenza	NN
cord-257662-viy65y72	322	12	virus	virus	NN
cord-257662-viy65y72	322	13	infection	infection	NN
cord-257662-viy65y72	322	14	in	in	IN
cord-257662-viy65y72	322	15	mice	mouse	NNS
cord-257662-viy65y72	322	16	Transactivation	Transactivation	NNP
cord-257662-viy65y72	322	17	of	of	IN
cord-257662-viy65y72	322	18	inducible	inducible	JJ
cord-257662-viy65y72	322	19	nitric	nitric	NN
cord-257662-viy65y72	322	20	oxide	oxide	NN
cord-257662-viy65y72	322	21	synthase	synthase	NN
cord-257662-viy65y72	322	22	gene	gene	NN
cord-257662-viy65y72	322	23	by	by	IN
cord-257662-viy65y72	322	24	Kruppel	Kruppel	NNP
cord-257662-viy65y72	322	25	-	-	HYPH
cord-257662-viy65y72	322	26	like	like	JJ
cord-257662-viy65y72	322	27	factor	factor	NN
cord-257662-viy65y72	322	28	6	6	CD
cord-257662-viy65y72	322	29	regulates	regulate	VBZ
cord-257662-viy65y72	322	30	apoptosis	apoptosis	NN
cord-257662-viy65y72	322	31	during	during	IN
cord-257662-viy65y72	322	32	influenza	influenza	NN
cord-257662-viy65y72	322	33	A	a	DT
cord-257662-viy65y72	322	34	virus	virus	NN
cord-257662-viy65y72	322	35	infection	infection	NN
cord-257662-viy65y72	322	36	CCR2	CCR2	NNP
cord-257662-viy65y72	322	37	+	+	CC
cord-257662-viy65y72	322	38	monocytederived	monocytederived	JJ
cord-257662-viy65y72	322	39	dendritic	dendritic	JJ
cord-257662-viy65y72	322	40	cells	cell	NNS
cord-257662-viy65y72	322	41	and	and	CC
cord-257662-viy65y72	322	42	exudate	exudate	NN
cord-257662-viy65y72	322	43	macrophages	macrophage	NNS
cord-257662-viy65y72	323	1	produce	produce	VB
cord-257662-viy65y72	323	2	influenzainduced	influenzainduce	VBN
cord-257662-viy65y72	323	3	pulmonary	pulmonary	JJ
cord-257662-viy65y72	323	4	immune	immune	JJ
cord-257662-viy65y72	323	5	pathology	pathology	NN
cord-257662-viy65y72	323	6	and	and	CC
cord-257662-viy65y72	323	7	mortality	mortality	NN
cord-257662-viy65y72	323	8	TNF	TNF	NNP
cord-257662-viy65y72	323	9	/	/	SYM
cord-257662-viy65y72	323	10	iNOS	inos	NN
cord-257662-viy65y72	323	11	-	-	HYPH
cord-257662-viy65y72	323	12	producing	produce	VBG
cord-257662-viy65y72	323	13	dendritic	dendritic	JJ
cord-257662-viy65y72	323	14	cells	cell	NNS
cord-257662-viy65y72	323	15	are	be	VBP
cord-257662-viy65y72	323	16	the	the	DT
cord-257662-viy65y72	323	17	necessary	necessary	JJ
cord-257662-viy65y72	323	18	evil	evil	NN
cord-257662-viy65y72	323	19	of	of	IN
cord-257662-viy65y72	323	20	lethal	lethal	JJ
cord-257662-viy65y72	323	21	influenza	influenza	NN
cord-257662-viy65y72	323	22	virus	virus	NN
cord-257662-viy65y72	323	23	infection	infection	NN
cord-257662-viy65y72	323	24	Pioglitazone	Pioglitazone	NNP
cord-257662-viy65y72	323	25	,	,	,
cord-257662-viy65y72	323	26	a	a	DT
cord-257662-viy65y72	323	27	specific	specific	JJ
cord-257662-viy65y72	323	28	ligand	ligand	NN
cord-257662-viy65y72	323	29	of	of	IN
cord-257662-viy65y72	323	30	peroxisome	peroxisome	NN
cord-257662-viy65y72	323	31	proliferator	proliferator	NN
cord-257662-viy65y72	323	32	-	-	HYPH
cord-257662-viy65y72	323	33	activated	activate	VBN
cord-257662-viy65y72	323	34	receptorgamma	receptorgamma	NN
cord-257662-viy65y72	323	35	,	,	,
cord-257662-viy65y72	323	36	accelerates	accelerate	VBZ
cord-257662-viy65y72	323	37	gastric	gastric	JJ
cord-257662-viy65y72	323	38	ulcer	ulcer	NN
cord-257662-viy65y72	323	39	healing	healing	NN
cord-257662-viy65y72	323	40	in	in	IN
cord-257662-viy65y72	323	41	rat	rat	NN
cord-257662-viy65y72	323	42	Evasion	evasion	NN
cord-257662-viy65y72	323	43	by	by	IN
cord-257662-viy65y72	323	44	stealth	stealth	NN
cord-257662-viy65y72	323	45	:	:	:
cord-257662-viy65y72	323	46	inefficient	inefficient	JJ
cord-257662-viy65y72	323	47	immune	immune	JJ
cord-257662-viy65y72	323	48	activation	activation	NN
cord-257662-viy65y72	323	49	underlies	underlie	VBZ
cord-257662-viy65y72	323	50	poor	poor	JJ
cord-257662-viy65y72	323	51	T	T	NNP
cord-257662-viy65y72	323	52	cell	cell	NN
cord-257662-viy65y72	323	53	response	response	NN
cord-257662-viy65y72	323	54	and	and	CC
cord-257662-viy65y72	323	55	severe	severe	JJ
cord-257662-viy65y72	323	56	disease	disease	NN
cord-257662-viy65y72	323	57	in	in	IN
cord-257662-viy65y72	323	58	SARS	SARS	NNP
cord-257662-viy65y72	323	59	-	-	HYPH
cord-257662-viy65y72	323	60	CoV	CoV	NNP
cord-257662-viy65y72	323	61	-	-	HYPH
cord-257662-viy65y72	323	62	infected	infect	VBN
cord-257662-viy65y72	323	63	mice	mouse	NNS
cord-257662-viy65y72	323	64	Induction	Induction	NNP
cord-257662-viy65y72	323	65	of	of	IN
cord-257662-viy65y72	323	66	alternatively	alternatively	RB
cord-257662-viy65y72	323	67	activated	activate	VBN
cord-257662-viy65y72	323	68	macrophages	macrophage	NNS
cord-257662-viy65y72	323	69	enhances	enhance	VBZ
cord-257662-viy65y72	323	70	pathogenesis	pathogenesis	NN
cord-257662-viy65y72	323	71	during	during	IN
cord-257662-viy65y72	323	72	severe	severe	JJ
cord-257662-viy65y72	323	73	acute	acute	JJ
cord-257662-viy65y72	323	74	respiratory	respiratory	JJ
cord-257662-viy65y72	323	75	syndrome	syndrome	NN
cord-257662-viy65y72	323	76	coronavirus	coronavirus	NN
cord-257662-viy65y72	323	77	infection	infection	NN
cord-257662-viy65y72	323	78	Suppression	Suppression	NNP
cord-257662-viy65y72	323	79	of	of	IN
cord-257662-viy65y72	323	80	herpes	herpes	NNP
cord-257662-viy65y72	323	81	simplex	simplex	NNP
cord-257662-viy65y72	323	82	virus	virus	NN
cord-257662-viy65y72	323	83	type	type	NN
cord-257662-viy65y72	323	84	1	1	CD
cord-257662-viy65y72	324	1	(	(	-LRB-
cord-257662-viy65y72	324	2	HSV-1)-induced	hsv-1)-induced	JJ
cord-257662-viy65y72	324	3	pneumonia	pneumonia	NN
cord-257662-viy65y72	324	4	in	in	IN
cord-257662-viy65y72	324	5	mice	mouse	NNS
cord-257662-viy65y72	324	6	by	by	IN
cord-257662-viy65y72	324	7	inhibition	inhibition	NN
cord-257662-viy65y72	324	8	of	of	IN
cord-257662-viy65y72	324	9	inducible	inducible	JJ
cord-257662-viy65y72	324	10	nitric	nitric	NN
cord-257662-viy65y72	324	11	oxide	oxide	NN
cord-257662-viy65y72	324	12	synthase	synthase	NN
cord-257662-viy65y72	324	13	(	(	-LRB-
cord-257662-viy65y72	325	1	iNOS	iNOS	NNP
cord-257662-viy65y72	325	2	,	,	,
cord-257662-viy65y72	325	3	NOS2	NOS2	NNP
cord-257662-viy65y72	325	4	)	)	-RRB-
cord-257662-viy65y72	326	1	Early	early	JJ
cord-257662-viy65y72	326	2	inhibition	inhibition	NN
cord-257662-viy65y72	326	3	of	of	IN
cord-257662-viy65y72	326	4	nitric	nitric	JJ
cord-257662-viy65y72	326	5	oxide	oxide	NN
cord-257662-viy65y72	326	6	production	production	NN
cord-257662-viy65y72	326	7	increases	increase	VBZ
cord-257662-viy65y72	326	8	HSV-1	hsv-1	RB
cord-257662-viy65y72	327	1	intranasal	intranasal	NN
cord-257662-viy65y72	327	2	infection	infection	NN
cord-257662-viy65y72	327	3	Microglia	Microglia	NNP
cord-257662-viy65y72	327	4	are	be	VBP
cord-257662-viy65y72	327	5	the	the	DT
cord-257662-viy65y72	327	6	major	major	JJ
cord-257662-viy65y72	327	7	cellular	cellular	JJ
cord-257662-viy65y72	327	8	source	source	NN
cord-257662-viy65y72	327	9	of	of	IN
cord-257662-viy65y72	327	10	inducible	inducible	JJ
cord-257662-viy65y72	327	11	nitric	nitric	NN
cord-257662-viy65y72	327	12	oxide	oxide	NN
cord-257662-viy65y72	327	13	synthase	synthase	NN
cord-257662-viy65y72	327	14	during	during	IN
cord-257662-viy65y72	327	15	experimental	experimental	JJ
cord-257662-viy65y72	327	16	herpes	herpe	NNS
cord-257662-viy65y72	327	17	encephalitis	encephalitis	NNP
cord-257662-viy65y72	327	18	Activation	Activation	NNP
cord-257662-viy65y72	327	19	of	of	IN
cord-257662-viy65y72	327	20	alveolar	alveolar	JJ
cord-257662-viy65y72	327	21	macrophages	macrophage	NNS
cord-257662-viy65y72	327	22	via	via	IN
cord-257662-viy65y72	327	23	the	the	DT
cord-257662-viy65y72	327	24	alternative	alternative	JJ
cord-257662-viy65y72	327	25	pathway	pathway	NN
cord-257662-viy65y72	327	26	in	in	IN
cord-257662-viy65y72	327	27	herpesvirusinduced	herpesvirusinduced	JJ
cord-257662-viy65y72	327	28	lung	lung	NN
cord-257662-viy65y72	327	29	fibrosis	fibrosis	NN
cord-257662-viy65y72	327	30	Pathological	pathological	JJ
cord-257662-viy65y72	327	31	changes	change	NNS
cord-257662-viy65y72	327	32	in	in	IN
cord-257662-viy65y72	327	33	the	the	DT
cord-257662-viy65y72	327	34	spleens	spleen	NNS
cord-257662-viy65y72	327	35	of	of	IN
cord-257662-viy65y72	327	36	gamma	gamma	NN
cord-257662-viy65y72	327	37	interferon	interferon	NN
cord-257662-viy65y72	327	38	receptor	receptor	NN
cord-257662-viy65y72	327	39	-	-	HYPH
cord-257662-viy65y72	327	40	deficient	deficient	JJ
cord-257662-viy65y72	327	41	mice	mouse	NNS
cord-257662-viy65y72	327	42	infected	infect	VBN
cord-257662-viy65y72	327	43	with	with	IN
cord-257662-viy65y72	327	44	murine	murine	JJ
cord-257662-viy65y72	327	45	gammaherpesvirus	gammaherpesvirus	NNP
cord-257662-viy65y72	327	46	:	:	:
cord-257662-viy65y72	327	47	a	a	DT
cord-257662-viy65y72	327	48	role	role	NN
cord-257662-viy65y72	327	49	for	for	IN
cord-257662-viy65y72	327	50	CD8	CD8	NNP
cord-257662-viy65y72	327	51	T	T	NNP
cord-257662-viy65y72	327	52	cells	cell	NNS
cord-257662-viy65y72	328	1	Murine	murine	JJ
cord-257662-viy65y72	328	2	gammaherpesvirus-68	gammaherpesvirus-68	CD
cord-257662-viy65y72	328	3	infection	infection	NN
cord-257662-viy65y72	328	4	causes	cause	VBZ
cord-257662-viy65y72	328	5	multi	multi	JJ
cord-257662-viy65y72	328	6	-	-	JJ
cord-257662-viy65y72	328	7	organ	organ	JJ
cord-257662-viy65y72	328	8	fibrosis	fibrosis	NN
cord-257662-viy65y72	328	9	and	and	CC
cord-257662-viy65y72	328	10	alters	alter	VBZ
cord-257662-viy65y72	328	11	leukocyte	leukocyte	NN
cord-257662-viy65y72	328	12	trafficking	trafficking	NN
cord-257662-viy65y72	328	13	in	in	IN
cord-257662-viy65y72	328	14	interferon	interferon	NN
cord-257662-viy65y72	328	15	-	-	HYPH
cord-257662-viy65y72	328	16	gamma	gamma	NN
cord-257662-viy65y72	328	17	receptor	receptor	NN
cord-257662-viy65y72	328	18	knockout	knockout	NN
cord-257662-viy65y72	328	19	mice	mouse	NNS
cord-257662-viy65y72	329	1	Lentivirus	lentivirus	NN
cord-257662-viy65y72	329	2	infection	infection	NN
cord-257662-viy65y72	329	3	causes	cause	VBZ
cord-257662-viy65y72	329	4	neuroinflammation	neuroinflammation	NN
cord-257662-viy65y72	329	5	and	and	CC
cord-257662-viy65y72	329	6	neuronal	neuronal	JJ
cord-257662-viy65y72	329	7	injury	injury	NN
cord-257662-viy65y72	329	8	in	in	IN
cord-257662-viy65y72	329	9	dorsal	dorsal	JJ
cord-257662-viy65y72	329	10	root	root	NN
cord-257662-viy65y72	329	11	ganglia	ganglion	NNS
cord-257662-viy65y72	329	12	:	:	:
cord-257662-viy65y72	330	1	pathogenic	pathogenic	JJ
cord-257662-viy65y72	330	2	effects	effect	NNS
cord-257662-viy65y72	330	3	of	of	IN
cord-257662-viy65y72	330	4	STAT-1	STAT-1	NNS
cord-257662-viy65y72	330	5	and	and	CC
cord-257662-viy65y72	330	6	inducible	inducible	JJ
cord-257662-viy65y72	330	7	nitric	nitric	NN
cord-257662-viy65y72	330	8	oxide	oxide	NN
cord-257662-viy65y72	330	9	synthase	synthase	NN
cord-257662-viy65y72	330	10	Myeloid	myeloid	NN
cord-257662-viy65y72	330	11	-	-	HYPH
cord-257662-viy65y72	330	12	derived	derive	VBN
cord-257662-viy65y72	330	13	suppressor	suppressor	NN
cord-257662-viy65y72	330	14	cells	cell	NNS
cord-257662-viy65y72	330	15	in	in	IN
cord-257662-viy65y72	330	16	murine	murine	JJ
cord-257662-viy65y72	330	17	retrovirus	retrovirus	NN
cord-257662-viy65y72	330	18	-	-	HYPH
cord-257662-viy65y72	330	19	induced	induce	VBN
cord-257662-viy65y72	330	20	AIDS	AIDS	NNP
cord-257662-viy65y72	330	21	inhibit	inhibit	VBP
cord-257662-viy65y72	330	22	T	T	NNP
cord-257662-viy65y72	330	23	-	-	HYPH
cord-257662-viy65y72	330	24	and	and	CC
cord-257662-viy65y72	330	25	B	b	NN
cord-257662-viy65y72	330	26	-	-	HYPH
cord-257662-viy65y72	330	27	cell	cell	NN
cord-257662-viy65y72	330	28	responses	response	NNS
cord-257662-viy65y72	330	29	in	in	IN
cord-257662-viy65y72	330	30	vitro	vitro	FW
cord-257662-viy65y72	330	31	that	that	WDT
cord-257662-viy65y72	330	32	are	be	VBP
cord-257662-viy65y72	330	33	used	use	VBN
cord-257662-viy65y72	330	34	to	to	TO
cord-257662-viy65y72	330	35	define	define	VB
cord-257662-viy65y72	330	36	the	the	DT
cord-257662-viy65y72	330	37	immunodeficiency	immunodeficiency	NN
cord-257662-viy65y72	330	38	Cytomegalovirus	Cytomegalovirus	NNP
cord-257662-viy65y72	330	39	impairs	impair	VBZ
cord-257662-viy65y72	330	40	antiviral	antiviral	JJ
cord-257662-viy65y72	330	41	CD8	CD8	NNP
cord-257662-viy65y72	330	42	+	+	CC
cord-257662-viy65y72	330	43	T	T	NNP
cord-257662-viy65y72	330	44	cell	cell	NN
cord-257662-viy65y72	330	45	immunity	immunity	NN
cord-257662-viy65y72	330	46	by	by	IN
cord-257662-viy65y72	330	47	recruiting	recruit	VBG
cord-257662-viy65y72	330	48	inflammatory	inflammatory	JJ
cord-257662-viy65y72	330	49	monocytes	monocyte	NNS
cord-257662-viy65y72	330	50	Emergence	emergence	NN
cord-257662-viy65y72	330	51	of	of	IN
cord-257662-viy65y72	330	52	distinct	distinct	JJ
cord-257662-viy65y72	330	53	multiarmed	multiarme	VBN
cord-257662-viy65y72	330	54	immunoregulatory	immunoregulatory	JJ
cord-257662-viy65y72	330	55	antigen	antigen	NN
cord-257662-viy65y72	330	56	-	-	HYPH
cord-257662-viy65y72	330	57	presenting	present	VBG
cord-257662-viy65y72	330	58	cells	cell	NNS
cord-257662-viy65y72	330	59	during	during	IN
cord-257662-viy65y72	330	60	persistent	persistent	JJ
cord-257662-viy65y72	330	61	viral	viral	JJ
cord-257662-viy65y72	330	62	infection	infection	NN
cord-257662-viy65y72	330	63	Transgenic	Transgenic	NNP
cord-257662-viy65y72	330	64	CCL2	CCL2	NNP
cord-257662-viy65y72	330	65	expression	expression	NN
cord-257662-viy65y72	330	66	in	in	IN
cord-257662-viy65y72	330	67	the	the	DT
cord-257662-viy65y72	330	68	central	central	JJ
cord-257662-viy65y72	330	69	nervous	nervous	JJ
cord-257662-viy65y72	330	70	system	system	NN
cord-257662-viy65y72	330	71	results	result	VBZ
cord-257662-viy65y72	330	72	in	in	IN
cord-257662-viy65y72	330	73	a	a	DT
cord-257662-viy65y72	330	74	dysregulated	dysregulate	VBN
cord-257662-viy65y72	330	75	immune	immune	JJ
cord-257662-viy65y72	330	76	response	response	NN
cord-257662-viy65y72	330	77	and	and	CC
cord-257662-viy65y72	330	78	enhanced	enhanced	JJ
cord-257662-viy65y72	330	79	lethality	lethality	NN
cord-257662-viy65y72	330	80	after	after	IN
cord-257662-viy65y72	330	81	coronavirus	coronavirus	NN
cord-257662-viy65y72	330	82	infection	infection	NN
cord-257662-viy65y72	330	83	Genetic	genetic	JJ
cord-257662-viy65y72	330	84	ablation	ablation	NN
cord-257662-viy65y72	330	85	of	of	IN
cord-257662-viy65y72	330	86	arginase	arginase	NN
cord-257662-viy65y72	330	87	1	1	CD
cord-257662-viy65y72	330	88	in	in	IN
cord-257662-viy65y72	330	89	macrophages	macrophage	NNS
cord-257662-viy65y72	330	90	and	and	CC
cord-257662-viy65y72	330	91	neutrophils	neutrophil	NNS
cord-257662-viy65y72	330	92	enhances	enhance	VBZ
cord-257662-viy65y72	330	93	clearance	clearance	NN
cord-257662-viy65y72	330	94	of	of	IN
cord-257662-viy65y72	330	95	an	an	DT
cord-257662-viy65y72	330	96	arthritogenic	arthritogenic	JJ
cord-257662-viy65y72	330	97	alphavirus	alphavirus	NN
cord-257662-viy65y72	330	98	Chronic	Chronic	NNP
cord-257662-viy65y72	330	99	but	but	CC
cord-257662-viy65y72	330	100	not	not	RB
cord-257662-viy65y72	330	101	acute	acute	JJ
cord-257662-viy65y72	330	102	virus	virus	NN
cord-257662-viy65y72	330	103	infection	infection	NN
cord-257662-viy65y72	330	104	induces	induce	VBZ
cord-257662-viy65y72	330	105	sustained	sustain	VBD
cord-257662-viy65y72	330	106	expansion	expansion	NN
cord-257662-viy65y72	330	107	of	of	IN
cord-257662-viy65y72	330	108	myeloid	myeloid	JJ
cord-257662-viy65y72	330	109	suppressor	suppressor	NN
cord-257662-viy65y72	330	110	cell	cell	NN
cord-257662-viy65y72	330	111	numbers	number	NNS
cord-257662-viy65y72	330	112	that	that	WDT
cord-257662-viy65y72	330	113	inhibit	inhibit	VBP
cord-257662-viy65y72	330	114	viral	viral	JJ
cord-257662-viy65y72	330	115	-	-	HYPH
cord-257662-viy65y72	330	116	specific	specific	JJ
cord-257662-viy65y72	330	117	T	t	NN
cord-257662-viy65y72	330	118	cell	cell	NN
cord-257662-viy65y72	330	119	immunity	immunity	NN
cord-257662-viy65y72	330	120	Hepatitis	Hepatitis	NNP
cord-257662-viy65y72	330	121	C	C	NNP
cord-257662-viy65y72	330	122	virus	virus	NN
cord-257662-viy65y72	330	123	targets	target	VBZ
cord-257662-viy65y72	330	124	over	over	IN
cord-257662-viy65y72	330	125	-	-	HYPH
cord-257662-viy65y72	330	126	expression	expression	NN
cord-257662-viy65y72	330	127	of	of	IN
cord-257662-viy65y72	330	128	arginase	arginase	NN
cord-257662-viy65y72	331	1	I	-PRON-	PRP
cord-257662-viy65y72	331	2	in	in	IN
cord-257662-viy65y72	331	3	hepatocarcinogenesis	hepatocarcinogenesis	NNP
cord-257662-viy65y72	332	1	CD163/	CD163/	NNP
cord-257662-viy65y72	333	1	CD16	CD16	NNP
cord-257662-viy65y72	333	2	coexpression	coexpression	NN
cord-257662-viy65y72	333	3	by	by	IN
cord-257662-viy65y72	333	4	circulating	circulate	VBG
cord-257662-viy65y72	333	5	monocytes	monocyte	NNS
cord-257662-viy65y72	333	6	/	/	SYM
cord-257662-viy65y72	333	7	macrophages	macrophage	NNS
cord-257662-viy65y72	333	8	in	in	IN
cord-257662-viy65y72	333	9	HIV	HIV	NNP
cord-257662-viy65y72	333	10	:	:	:
cord-257662-viy65y72	333	11	potential	potential	JJ
cord-257662-viy65y72	333	12	biomarkers	biomarker	NNS
cord-257662-viy65y72	333	13	for	for	IN
cord-257662-viy65y72	333	14	HIV	HIV	NNP
cord-257662-viy65y72	333	15	infection	infection	NN
cord-257662-viy65y72	333	16	and	and	CC
cord-257662-viy65y72	333	17	AIDS	AIDS	NNP
cord-257662-viy65y72	333	18	progression	progression	NN
cord-257662-viy65y72	333	19	Expansion	Expansion	NNP
cord-257662-viy65y72	333	20	of	of	IN
cord-257662-viy65y72	333	21	monocytic	monocytic	JJ
cord-257662-viy65y72	333	22	myeloid	myeloid	NN
cord-257662-viy65y72	333	23	-	-	HYPH
cord-257662-viy65y72	333	24	derived	derive	VBN
cord-257662-viy65y72	333	25	suppressor	suppressor	NN
cord-257662-viy65y72	333	26	cells	cell	NNS
cord-257662-viy65y72	333	27	dampens	dampen	VBZ
cord-257662-viy65y72	333	28	T	T	NNP
cord-257662-viy65y72	333	29	cell	cell	NN
cord-257662-viy65y72	333	30	function	function	NN
cord-257662-viy65y72	333	31	in	in	IN
cord-257662-viy65y72	333	32	HIV-1-seropositive	hiv-1-seropositive	JJ
cord-257662-viy65y72	333	33	individuals	individual	NNS
cord-257662-viy65y72	334	1	Increased	increase	VBN
cord-257662-viy65y72	335	1	level	level	NN
cord-257662-viy65y72	335	2	of	of	IN
cord-257662-viy65y72	335	3	arginase	arginase	NN
cord-257662-viy65y72	335	4	activity	activity	NN
cord-257662-viy65y72	335	5	correlates	correlate	VBZ
cord-257662-viy65y72	335	6	with	with	IN
cord-257662-viy65y72	335	7	disease	disease	NN
cord-257662-viy65y72	335	8	severity	severity	NN
cord-257662-viy65y72	335	9	in	in	IN
cord-257662-viy65y72	335	10	HIV	HIV	NNP
cord-257662-viy65y72	335	11	-	-	HYPH
cord-257662-viy65y72	335	12	seropositive	seropositive	JJ
cord-257662-viy65y72	335	13	patients	patient	NNS
cord-257662-viy65y72	336	1	Antiretroviral	Antiretroviral	NNP
cord-257662-viy65y72	336	2	therapy	therapy	NN
cord-257662-viy65y72	336	3	abrogates	abrogate	VBZ
cord-257662-viy65y72	336	4	association	association	NN
cord-257662-viy65y72	336	5	between	between	IN
cord-257662-viy65y72	336	6	arginase	arginase	NNP
cord-257662-viy65y72	336	7	activity	activity	NNP
cord-257662-viy65y72	336	8	and	and	CC
cord-257662-viy65y72	336	9	HIV	HIV	NNP
cord-257662-viy65y72	336	10	disease	disease	NN
cord-257662-viy65y72	336	11	severity	severity	NN
cord-257662-viy65y72	336	12	HIV	HIV	NNP
cord-257662-viy65y72	336	13	type	type	NN
cord-257662-viy65y72	336	14	1	1	CD
cord-257662-viy65y72	336	15	gp120-induced	gp120-induced	NNP
cord-257662-viy65y72	336	16	expansion	expansion	NN
cord-257662-viy65y72	336	17	of	of	IN
cord-257662-viy65y72	336	18	myeloid	myeloid	JJ
cord-257662-viy65y72	336	19	derived	derive	VBN
cord-257662-viy65y72	336	20	suppressor	suppressor	NN
cord-257662-viy65y72	336	21	cells	cell	NNS
cord-257662-viy65y72	336	22	is	be	VBZ
cord-257662-viy65y72	336	23	dependent	dependent	JJ
cord-257662-viy65y72	336	24	on	on	IN
cord-257662-viy65y72	336	25	interleukin	interleukin	NN
cord-257662-viy65y72	336	26	6	6	CD
cord-257662-viy65y72	336	27	and	and	CC
cord-257662-viy65y72	336	28	suppresses	suppress	VBZ
cord-257662-viy65y72	336	29	immunity	immunity	NN
cord-257662-viy65y72	336	30	Arginase	Arginase	NNP
cord-257662-viy65y72	336	31	activity	activity	NN
cord-257662-viy65y72	336	32	in	in	IN
cord-257662-viy65y72	336	33	the	the	DT
cord-257662-viy65y72	336	34	blood	blood	NN
cord-257662-viy65y72	336	35	of	of	IN
cord-257662-viy65y72	336	36	patients	patient	NNS
cord-257662-viy65y72	336	37	with	with	IN
cord-257662-viy65y72	336	38	visceral	visceral	JJ
cord-257662-viy65y72	336	39	leishmaniasis	leishmaniasis	NN
cord-257662-viy65y72	336	40	and	and	CC
cord-257662-viy65y72	336	41	HIV	HIV	NNP
cord-257662-viy65y72	336	42	infection	infection	NN
cord-257662-viy65y72	336	43	Hepatitis	Hepatitis	NNP
cord-257662-viy65y72	336	44	B	B	NNP
cord-257662-viy65y72	336	45	virus	virus	NN
cord-257662-viy65y72	336	46	infection	infection	NN
cord-257662-viy65y72	336	47	and	and	CC
cord-257662-viy65y72	336	48	immunopathogenesis	immunopathogenesis	NN
cord-257662-viy65y72	336	49	in	in	IN
cord-257662-viy65y72	336	50	a	a	DT
cord-257662-viy65y72	336	51	humanized	humanized	JJ
cord-257662-viy65y72	336	52	mouse	mouse	NN
cord-257662-viy65y72	336	53	model	model	NN
cord-257662-viy65y72	336	54	:	:	:
cord-257662-viy65y72	337	1	induction	induction	NN
cord-257662-viy65y72	337	2	of	of	IN
cord-257662-viy65y72	337	3	human	human	JJ
cord-257662-viy65y72	337	4	-	-	HYPH
cord-257662-viy65y72	337	5	specific	specific	JJ
cord-257662-viy65y72	337	6	liver	liver	NN
cord-257662-viy65y72	337	7	fibrosis	fibrosis	NN
cord-257662-viy65y72	337	8	and	and	CC
cord-257662-viy65y72	337	9	M2-like	M2-like	NNS
cord-257662-viy65y72	337	10	macrophages	macrophage	NNS
cord-257662-viy65y72	337	11	Increased	increase	VBN
cord-257662-viy65y72	337	12	levels	level	NNS
cord-257662-viy65y72	337	13	of	of	IN
cord-257662-viy65y72	337	14	arginase	arginase	NN
cord-257662-viy65y72	337	15	in	in	IN
cord-257662-viy65y72	337	16	patients	patient	NNS
cord-257662-viy65y72	337	17	with	with	IN
cord-257662-viy65y72	337	18	acute	acute	JJ
cord-257662-viy65y72	337	19	hepatitis	hepatitis	NN
cord-257662-viy65y72	337	20	B	B	NNP
cord-257662-viy65y72	337	21	suppress	suppress	VB
cord-257662-viy65y72	337	22	antiviral	antiviral	JJ
cord-257662-viy65y72	337	23	T	t	NN
cord-257662-viy65y72	337	24	cells	cell	NNS
cord-257662-viy65y72	338	1	Functional	functional	JJ
cord-257662-viy65y72	338	2	skewing	skewing	NN
cord-257662-viy65y72	338	3	of	of	IN
cord-257662-viy65y72	338	4	the	the	DT
cord-257662-viy65y72	338	5	global	global	JJ
cord-257662-viy65y72	338	6	CD8	CD8	NNP
cord-257662-viy65y72	338	7	T	T	NNP
cord-257662-viy65y72	338	8	cell	cell	NN
cord-257662-viy65y72	338	9	population	population	NN
cord-257662-viy65y72	338	10	in	in	IN
cord-257662-viy65y72	338	11	chronic	chronic	JJ
cord-257662-viy65y72	338	12	hepatitis	hepatitis	NN
cord-257662-viy65y72	338	13	B	B	NNP
cord-257662-viy65y72	338	14	virus	virus	NN
cord-257662-viy65y72	338	15	infection	infection	NN
cord-257662-viy65y72	339	1	Invariant	invariant	JJ
cord-257662-viy65y72	339	2	NKT	NKT	NNP
cord-257662-viy65y72	339	3	cells	cell	NNS
cord-257662-viy65y72	339	4	reduce	reduce	VBP
cord-257662-viy65y72	339	5	the	the	DT
cord-257662-viy65y72	339	6	immunosuppressive	immunosuppressive	JJ
cord-257662-viy65y72	339	7	activity	activity	NN
cord-257662-viy65y72	339	8	of	of	IN
cord-257662-viy65y72	339	9	influenza	influenza	NN
cord-257662-viy65y72	339	10	A	a	DT
cord-257662-viy65y72	339	11	virus	virus	NN
cord-257662-viy65y72	339	12	-	-	HYPH
cord-257662-viy65y72	339	13	induced	induce	VBN
cord-257662-viy65y72	339	14	myeloid	myeloid	NN
cord-257662-viy65y72	339	15	-	-	HYPH
cord-257662-viy65y72	339	16	derived	derive	VBN
cord-257662-viy65y72	339	17	suppressor	suppressor	NN
cord-257662-viy65y72	339	18	cells	cell	NNS
cord-257662-viy65y72	339	19	in	in	IN
cord-257662-viy65y72	339	20	mice	mouse	NNS
cord-257662-viy65y72	339	21	and	and	CC
cord-257662-viy65y72	339	22	humans	human	NNS
cord-257662-viy65y72	339	23	Accumulation	Accumulation	NNP
cord-257662-viy65y72	339	24	of	of	IN
cord-257662-viy65y72	339	25	CD11b(+)Gr-1(+	CD11b(+)Gr-1(+	NNPS
cord-257662-viy65y72	340	1	)	)	-RRB-
cord-257662-viy65y72	340	2	cells	cell	NNS
cord-257662-viy65y72	340	3	in	in	IN
cord-257662-viy65y72	340	4	the	the	DT
cord-257662-viy65y72	340	5	lung	lung	NN
cord-257662-viy65y72	340	6	,	,	,
cord-257662-viy65y72	340	7	blood	blood	NN
cord-257662-viy65y72	340	8	and	and	CC
cord-257662-viy65y72	340	9	bone	bone	NN
cord-257662-viy65y72	340	10	marrow	marrow	NN
cord-257662-viy65y72	340	11	of	of	IN
cord-257662-viy65y72	340	12	mice	mouse	NNS
cord-257662-viy65y72	340	13	infected	infect	VBN
cord-257662-viy65y72	340	14	with	with	IN
cord-257662-viy65y72	340	15	highly	highly	RB
cord-257662-viy65y72	340	16	pathogenic	pathogenic	JJ
cord-257662-viy65y72	340	17	H5N1	H5N1	NNP
cord-257662-viy65y72	340	18	and	and	CC
cord-257662-viy65y72	340	19	H1N1	H1N1	NNP
cord-257662-viy65y72	340	20	influenza	influenza	NN
cord-257662-viy65y72	340	21	viruses	viruse	VBZ
cord-257662-viy65y72	340	22	Virus	virus	NN
cord-257662-viy65y72	340	23	-	-	HYPH
cord-257662-viy65y72	340	24	helminth	helminth	JJ
cord-257662-viy65y72	340	25	coinfection	coinfection	NN
cord-257662-viy65y72	340	26	reveals	reveal	VBZ
cord-257662-viy65y72	340	27	a	a	DT
cord-257662-viy65y72	340	28	microbiota	microbiota	NN
cord-257662-viy65y72	340	29	-	-	HYPH
cord-257662-viy65y72	340	30	independent	independent	JJ
cord-257662-viy65y72	340	31	mechanism	mechanism	NN
cord-257662-viy65y72	340	32	of	of	IN
cord-257662-viy65y72	340	33	immunomodulation	immunomodulation	NN
cord-257662-viy65y72	340	34	Biochemistry	Biochemistry	NNP
cord-257662-viy65y72	340	35	of	of	IN
cord-257662-viy65y72	340	36	nitric	nitric	JJ
cord-257662-viy65y72	340	37	oxide	oxide	NN
cord-257662-viy65y72	340	38	and	and	CC
cord-257662-viy65y72	340	39	its	-PRON-	PRP$
cord-257662-viy65y72	340	40	redoxactivated	redoxactivated	JJ
cord-257662-viy65y72	340	41	forms	form	NNS
cord-257662-viy65y72	340	42	Alterations	alteration	NNS
cord-257662-viy65y72	340	43	of	of	IN
cord-257662-viy65y72	340	44	ribonucleotide	ribonucleotide	NN
cord-257662-viy65y72	340	45	reductase	reductase	NN
cord-257662-viy65y72	340	46	activity	activity	NN
cord-257662-viy65y72	340	47	following	follow	VBG
cord-257662-viy65y72	340	48	induction	induction	NN
cord-257662-viy65y72	340	49	of	of	IN
cord-257662-viy65y72	340	50	the	the	DT
cord-257662-viy65y72	340	51	nitrite	nitrite	NN
cord-257662-viy65y72	340	52	-	-	HYPH
cord-257662-viy65y72	340	53	generating	generate	VBG
cord-257662-viy65y72	340	54	pathway	pathway	NN
cord-257662-viy65y72	340	55	in	in	IN
cord-257662-viy65y72	340	56	adenocarcinoma	adenocarcinoma	NN
cord-257662-viy65y72	340	57	cells	cell	NNS
cord-257662-viy65y72	340	58	Inhibition	inhibition	NN
cord-257662-viy65y72	340	59	of	of	IN
cord-257662-viy65y72	340	60	tumor	tumor	NN
cord-257662-viy65y72	340	61	cell	cell	NN
cord-257662-viy65y72	340	62	ribonucleotide	ribonucleotide	NN
cord-257662-viy65y72	340	63	reductase	reductase	NN
cord-257662-viy65y72	340	64	by	by	IN
cord-257662-viy65y72	340	65	macrophage	macrophage	NN
cord-257662-viy65y72	340	66	-	-	HYPH
cord-257662-viy65y72	340	67	derived	derive	VBN
cord-257662-viy65y72	340	68	nitric	nitric	NN
cord-257662-viy65y72	340	69	oxide	oxide	NN
cord-257662-viy65y72	340	70	DNA	dna	NN
cord-257662-viy65y72	340	71	deaminating	deaminating	NN
cord-257662-viy65y72	340	72	ability	ability	NN
cord-257662-viy65y72	340	73	and	and	CC
cord-257662-viy65y72	340	74	genotoxicity	genotoxicity	NN
cord-257662-viy65y72	340	75	of	of	IN
cord-257662-viy65y72	340	76	nitric	nitric	NN
cord-257662-viy65y72	340	77	oxide	oxide	NN
cord-257662-viy65y72	340	78	and	and	CC
cord-257662-viy65y72	340	79	its	-PRON-	PRP$
cord-257662-viy65y72	340	80	progenitors	progenitor	NNS
cord-257662-viy65y72	340	81	DNA	dna	NN
cord-257662-viy65y72	340	82	damage	damage	NN
cord-257662-viy65y72	340	83	and	and	CC
cord-257662-viy65y72	340	84	mutation	mutation	NN
cord-257662-viy65y72	340	85	in	in	IN
cord-257662-viy65y72	340	86	human	human	JJ
cord-257662-viy65y72	340	87	cells	cell	NNS
cord-257662-viy65y72	340	88	exposed	expose	VBN
cord-257662-viy65y72	340	89	to	to	IN
cord-257662-viy65y72	340	90	nitric	nitric	JJ
cord-257662-viy65y72	340	91	oxide	oxide	NN
cord-257662-viy65y72	340	92	in	in	IN
cord-257662-viy65y72	340	93	vitro	vitro	FW
cord-257662-viy65y72	340	94	Factor(s	Factor(s	NNP
cord-257662-viy65y72	340	95	)	)	-RRB-
cord-257662-viy65y72	340	96	present	present	VBP
cord-257662-viy65y72	340	97	in	in	IN
cord-257662-viy65y72	340	98	herpes	herpes	NNP
cord-257662-viy65y72	340	99	simplex	simplex	NNP
cord-257662-viy65y72	340	100	virus	virus	NN
cord-257662-viy65y72	340	101	type	type	NN
cord-257662-viy65y72	340	102	1-infected	1-infected	CD
cord-257662-viy65y72	340	103	cells	cell	NNS
cord-257662-viy65y72	340	104	can	can	MD
cord-257662-viy65y72	340	105	compensate	compensate	VB
cord-257662-viy65y72	340	106	for	for	IN
cord-257662-viy65y72	340	107	the	the	DT
cord-257662-viy65y72	340	108	loss	loss	NN
cord-257662-viy65y72	340	109	of	of	IN
cord-257662-viy65y72	340	110	the	the	DT
cord-257662-viy65y72	340	111	large	large	JJ
cord-257662-viy65y72	340	112	subunit	subunit	NN
cord-257662-viy65y72	340	113	of	of	IN
cord-257662-viy65y72	340	114	the	the	DT
cord-257662-viy65y72	340	115	viral	viral	JJ
cord-257662-viy65y72	340	116	ribonucleotide	ribonucleotide	NN
cord-257662-viy65y72	340	117	reductase	reductase	NN
cord-257662-viy65y72	340	118	:	:	:
cord-257662-viy65y72	340	119	characterization	characterization	NN
cord-257662-viy65y72	340	120	of	of	IN
cord-257662-viy65y72	340	121	an	an	DT
cord-257662-viy65y72	340	122	ICP6	ICP6	NNP
cord-257662-viy65y72	340	123	deletion	deletion	NN
cord-257662-viy65y72	340	124	mutant	mutant	JJ
cord-257662-viy65y72	341	1	A	a	DT
cord-257662-viy65y72	341	2	herpes	herpes	NN
cord-257662-viy65y72	341	3	simplex	simplex	NN
cord-257662-viy65y72	341	4	virus	virus	NN
cord-257662-viy65y72	341	5	ribonucleotide	ribonucleotide	NN
cord-257662-viy65y72	341	6	reductase	reductase	NN
cord-257662-viy65y72	341	7	deletion	deletion	NN
cord-257662-viy65y72	341	8	mutant	mutant	NN
cord-257662-viy65y72	341	9	is	be	VBZ
cord-257662-viy65y72	341	10	defective	defective	JJ
cord-257662-viy65y72	341	11	for	for	IN
cord-257662-viy65y72	341	12	productive	productive	JJ
cord-257662-viy65y72	341	13	acute	acute	JJ
cord-257662-viy65y72	341	14	and	and	CC
cord-257662-viy65y72	341	15	reactivatable	reactivatable	JJ
cord-257662-viy65y72	341	16	latent	latent	JJ
cord-257662-viy65y72	341	17	infections	infection	NNS
cord-257662-viy65y72	341	18	of	of	IN
cord-257662-viy65y72	341	19	mice	mouse	NNS
cord-257662-viy65y72	341	20	and	and	CC
cord-257662-viy65y72	341	21	for	for	IN
cord-257662-viy65y72	341	22	replication	replication	NN
cord-257662-viy65y72	341	23	in	in	IN
cord-257662-viy65y72	341	24	mouse	mouse	NN
cord-257662-viy65y72	341	25	cells	cell	NNS
cord-257662-viy65y72	342	1	Nitric	nitric	NN
cord-257662-viy65y72	342	2	oxide	oxide	NN
cord-257662-viy65y72	342	3	donors	donor	NNS
cord-257662-viy65y72	342	4	inhibit	inhibit	VBP
cord-257662-viy65y72	342	5	the	the	DT
cord-257662-viy65y72	342	6	coxsackievirus	coxsackievirus	NNP
cord-257662-viy65y72	342	7	B3	B3	NNP
cord-257662-viy65y72	342	8	proteinases	proteinases	NNP
cord-257662-viy65y72	342	9	2A	2A	NNP
cord-257662-viy65y72	342	10	and	and	CC
cord-257662-viy65y72	342	11	3C	3c	NN
cord-257662-viy65y72	342	12	in	in	IN
cord-257662-viy65y72	342	13	vitro	vitro	FW
cord-257662-viy65y72	342	14	,	,	,
cord-257662-viy65y72	342	15	virus	virus	NN
cord-257662-viy65y72	342	16	production	production	NN
cord-257662-viy65y72	342	17	in	in	IN
cord-257662-viy65y72	342	18	cells	cell	NNS
cord-257662-viy65y72	342	19	,	,	,
cord-257662-viy65y72	342	20	and	and	CC
cord-257662-viy65y72	342	21	signs	sign	NNS
cord-257662-viy65y72	342	22	of	of	IN
cord-257662-viy65y72	342	23	myocarditis	myocarditis	NN
cord-257662-viy65y72	342	24	in	in	IN
cord-257662-viy65y72	342	25	virus	virus	NN
cord-257662-viy65y72	342	26	-	-	HYPH
cord-257662-viy65y72	342	27	infected	infect	VBN
cord-257662-viy65y72	342	28	mice	mouse	NNS
cord-257662-viy65y72	342	29	Molecular	molecular	JJ
cord-257662-viy65y72	342	30	basis	basis	NN
cord-257662-viy65y72	342	31	of	of	IN
cord-257662-viy65y72	342	32	"	"	``
cord-257662-viy65y72	342	33	suppressor	suppressor	NN
cord-257662-viy65y72	342	34	"	"	''
cord-257662-viy65y72	342	35	macrophages	macrophage	NNS
cord-257662-viy65y72	342	36	.	.	.
cord-257662-viy65y72	343	1	Arginine	arginine	NN
cord-257662-viy65y72	343	2	metabolism	metabolism	NN
cord-257662-viy65y72	343	3	via	via	IN
cord-257662-viy65y72	343	4	the	the	DT
cord-257662-viy65y72	343	5	nitric	nitric	NN
cord-257662-viy65y72	343	6	oxide	oxide	NN
cord-257662-viy65y72	343	7	synthetase	synthetase	NN
cord-257662-viy65y72	343	8	pathway	pathway	NN
cord-257662-viy65y72	343	9	Selection	selection	NN
cord-257662-viy65y72	343	10	of	of	IN
cord-257662-viy65y72	343	11	genetic	genetic	JJ
cord-257662-viy65y72	343	12	variants	variant	NNS
cord-257662-viy65y72	343	13	of	of	IN
cord-257662-viy65y72	343	14	lymphocytic	lymphocytic	JJ
cord-257662-viy65y72	343	15	choriomeningitis	choriomeningitis	NNP
cord-257662-viy65y72	343	16	virus	virus	NN
cord-257662-viy65y72	343	17	in	in	IN
cord-257662-viy65y72	343	18	spleens	spleen	NNS
cord-257662-viy65y72	343	19	of	of	IN
cord-257662-viy65y72	343	20	persistently	persistently	RB
cord-257662-viy65y72	343	21	infected	infect	VBN
cord-257662-viy65y72	343	22	mice	mouse	NNS
cord-257662-viy65y72	343	23	Massive	massive	JJ
cord-257662-viy65y72	343	24	expansion	expansion	NN
cord-257662-viy65y72	343	25	of	of	IN
cord-257662-viy65y72	343	26	antigen	antigen	NN
cord-257662-viy65y72	343	27	-	-	HYPH
cord-257662-viy65y72	343	28	specific	specific	JJ
cord-257662-viy65y72	343	29	CD8	CD8	NNP
cord-257662-viy65y72	343	30	+	+	CC
cord-257662-viy65y72	343	31	T	t	NN
cord-257662-viy65y72	343	32	cells	cell	NNS
cord-257662-viy65y72	343	33	during	during	IN
cord-257662-viy65y72	343	34	an	an	DT
cord-257662-viy65y72	343	35	acute	acute	JJ
cord-257662-viy65y72	343	36	virus	virus	NN
cord-257662-viy65y72	343	37	infection	infection	NN
cord-257662-viy65y72	343	38	Viral	viral	JJ
cord-257662-viy65y72	343	39	persistence	persistence	NN
cord-257662-viy65y72	343	40	alters	alter	VBZ
cord-257662-viy65y72	343	41	CD8	CD8	NNP
cord-257662-viy65y72	343	42	T	T	NNP
cord-257662-viy65y72	343	43	-	-	HYPH
cord-257662-viy65y72	343	44	cell	cell	NN
cord-257662-viy65y72	343	45	immunodominance	immunodominance	NN
cord-257662-viy65y72	343	46	and	and	CC
cord-257662-viy65y72	343	47	tissue	tissue	NN
cord-257662-viy65y72	343	48	distribution	distribution	NN
cord-257662-viy65y72	343	49	and	and	CC
cord-257662-viy65y72	343	50	results	result	NNS
cord-257662-viy65y72	343	51	in	in	IN
cord-257662-viy65y72	343	52	distinct	distinct	JJ
cord-257662-viy65y72	343	53	stages	stage	NNS
cord-257662-viy65y72	343	54	of	of	IN
cord-257662-viy65y72	343	55	functional	functional	JJ
cord-257662-viy65y72	343	56	impairment	impairment	NN
cord-257662-viy65y72	343	57	Macrophage	macrophage	NN
cord-257662-viy65y72	343	58	and	and	CC
cord-257662-viy65y72	343	59	T	T	NNP
cord-257662-viy65y72	343	60	cell	cell	NN
cord-257662-viy65y72	343	61	produced	produce	VBN
cord-257662-viy65y72	343	62	IL-10	IL-10	NNP
cord-257662-viy65y72	343	63	promotes	promote	VBZ
cord-257662-viy65y72	343	64	viral	viral	JJ
cord-257662-viy65y72	343	65	chronicity	chronicity	NN
cord-257662-viy65y72	344	1	Innate	innate	JJ
cord-257662-viy65y72	344	2	immune	immune	JJ
cord-257662-viy65y72	344	3	CD11b+Gr-1	CD11b+Gr-1	NNP
cord-257662-viy65y72	344	4	+	+	CC
cord-257662-viy65y72	344	5	cells	cell	NNS
cord-257662-viy65y72	344	6	,	,	,
cord-257662-viy65y72	344	7	suppressor	suppressor	NN
cord-257662-viy65y72	344	8	cells	cell	NNS
cord-257662-viy65y72	344	9	,	,	,
cord-257662-viy65y72	344	10	affect	affect	VBP
cord-257662-viy65y72	344	11	the	the	DT
cord-257662-viy65y72	344	12	immune	immune	JJ
cord-257662-viy65y72	344	13	response	response	NN
cord-257662-viy65y72	344	14	during	during	IN
cord-257662-viy65y72	344	15	Theiler	Theiler	NNP
cord-257662-viy65y72	344	16	's	's	POS
cord-257662-viy65y72	344	17	virus	virus	NN
cord-257662-viy65y72	344	18	-	-	HYPH
cord-257662-viy65y72	344	19	induced	induce	VBN
cord-257662-viy65y72	344	20	demyelinating	demyelinate	VBG
cord-257662-viy65y72	344	21	disease	disease	NN
cord-257662-viy65y72	344	22	Clinical	clinical	JJ
cord-257662-viy65y72	344	23	significance	significance	NN
cord-257662-viy65y72	344	24	and	and	CC
cord-257662-viy65y72	344	25	functional	functional	JJ
cord-257662-viy65y72	344	26	studies	study	NNS
cord-257662-viy65y72	344	27	of	of	IN
cord-257662-viy65y72	344	28	myeloid	myeloid	NN
cord-257662-viy65y72	344	29	-	-	HYPH
cord-257662-viy65y72	344	30	derived	derive	VBN
cord-257662-viy65y72	344	31	suppressor	suppressor	NN
cord-257662-viy65y72	344	32	cells	cell	NNS
cord-257662-viy65y72	344	33	in	in	IN
cord-257662-viy65y72	344	34	chronic	chronic	JJ
cord-257662-viy65y72	344	35	hepatitis	hepatitis	NN
cord-257662-viy65y72	344	36	C	c	NN
cord-257662-viy65y72	344	37	patients	patient	NNS
cord-257662-viy65y72	345	1	Myeloid	myeloid	NN
cord-257662-viy65y72	345	2	suppressor	suppressor	NN
cord-257662-viy65y72	345	3	cells	cell	NNS
cord-257662-viy65y72	345	4	induced	induce	VBN
cord-257662-viy65y72	345	5	by	by	IN
cord-257662-viy65y72	345	6	hepatitis	hepatitis	NN
cord-257662-viy65y72	345	7	C	C	NNP
cord-257662-viy65y72	345	8	virus	virus	NN
cord-257662-viy65y72	345	9	suppress	suppress	VBP
cord-257662-viy65y72	345	10	T	t	NN
cord-257662-viy65y72	345	11	-	-	HYPH
cord-257662-viy65y72	345	12	cell	cell	NN
cord-257662-viy65y72	345	13	responses	response	NNS
cord-257662-viy65y72	345	14	through	through	IN
cord-257662-viy65y72	345	15	the	the	DT
cord-257662-viy65y72	345	16	production	production	NN
cord-257662-viy65y72	345	17	of	of	IN
cord-257662-viy65y72	345	18	reactive	reactive	JJ
cord-257662-viy65y72	345	19	oxygen	oxygen	NN
cord-257662-viy65y72	345	20	species	specie	NNS
cord-257662-viy65y72	345	21	Macrophage	macrophage	NN
cord-257662-viy65y72	345	22	polarization	polarization	NN
cord-257662-viy65y72	345	23	and	and	CC
cord-257662-viy65y72	345	24	HIV-1	HIV-1	NNP
cord-257662-viy65y72	345	25	infection	infection	NN
cord-257662-viy65y72	345	26	Contribution	Contribution	NNP
cord-257662-viy65y72	345	27	of	of	IN
cord-257662-viy65y72	345	28	immune	immune	JJ
cord-257662-viy65y72	345	29	activation	activation	NN
cord-257662-viy65y72	345	30	to	to	IN
cord-257662-viy65y72	345	31	the	the	DT
cord-257662-viy65y72	345	32	pathogenesis	pathogenesis	NN
cord-257662-viy65y72	345	33	and	and	CC
cord-257662-viy65y72	345	34	transmission	transmission	NN
cord-257662-viy65y72	345	35	of	of	IN
cord-257662-viy65y72	345	36	human	human	JJ
cord-257662-viy65y72	345	37	immunodeficiency	immunodeficiency	NN
cord-257662-viy65y72	345	38	virus	virus	NN
cord-257662-viy65y72	345	39	type	type	NN
cord-257662-viy65y72	345	40	1	1	CD
cord-257662-viy65y72	345	41	infection	infection	NN
cord-257662-viy65y72	345	42	Hepatitis	Hepatitis	NNP
cord-257662-viy65y72	345	43	B	B	NNP
cord-257662-viy65y72	345	44	virus	virus	NN
cord-257662-viy65y72	345	45	infection	infection	NN
cord-257662-viy65y72	345	46	HPV16	hpv16	NN
cord-257662-viy65y72	346	1	tumor	tumor	NN
cord-257662-viy65y72	346	2	associated	associate	VBN
cord-257662-viy65y72	346	3	macrophages	macrophage	NNS
cord-257662-viy65y72	346	4	suppress	suppress	VBP
cord-257662-viy65y72	346	5	antitumor	antitumor	JJ
cord-257662-viy65y72	346	6	T	t	NN
cord-257662-viy65y72	346	7	cell	cell	NN
cord-257662-viy65y72	346	8	responses	response	NNS
cord-257662-viy65y72	346	9	Myeloid	myeloid	NN
cord-257662-viy65y72	346	10	-	-	HYPH
cord-257662-viy65y72	346	11	derived	derive	VBN
cord-257662-viy65y72	346	12	suppressor	suppressor	NN
cord-257662-viy65y72	346	13	cells	cell	NNS
cord-257662-viy65y72	346	14	:	:	:
cord-257662-viy65y72	346	15	the	the	DT
cord-257662-viy65y72	346	16	dark	dark	JJ
cord-257662-viy65y72	346	17	knight	knight	NN
cord-257662-viy65y72	346	18	or	or	CC
cord-257662-viy65y72	346	19	the	the	DT
cord-257662-viy65y72	346	20	joker	joker	NN
cord-257662-viy65y72	346	21	in	in	IN
cord-257662-viy65y72	346	22	viral	viral	JJ
cord-257662-viy65y72	346	23	infections	infection	NNS
cord-257662-viy65y72	346	24	?	?	.
cord-257662-viy65y72	347	1	Murine	murine	JJ
cord-257662-viy65y72	347	2	gammaherpesvirus	gammaherpesvirus	NN
cord-257662-viy65y72	347	3	-	-	HYPH
cord-257662-viy65y72	347	4	induced	induce	VBN
cord-257662-viy65y72	347	5	fibrosis	fibrosis	NN
cord-257662-viy65y72	347	6	is	be	VBZ
cord-257662-viy65y72	347	7	associated	associate	VBN
cord-257662-viy65y72	347	8	with	with	IN
cord-257662-viy65y72	347	9	the	the	DT
cord-257662-viy65y72	347	10	development	development	NN
cord-257662-viy65y72	347	11	of	of	IN
cord-257662-viy65y72	347	12	alternatively	alternatively	RB
cord-257662-viy65y72	347	13	activated	activate	VBN
cord-257662-viy65y72	347	14	macrophages	macrophage	NNS
cord-257662-viy65y72	347	15	Work	work	NN
cord-257662-viy65y72	347	16	in	in	IN
cord-257662-viy65y72	347	17	Dr.	Dr.	NNP
cord-257662-viy65y72	347	18	Morrison	Morrison	NNP
cord-257662-viy65y72	347	19	's	's	POS
cord-257662-viy65y72	347	20	laboratory	laboratory	NN
cord-257662-viy65y72	347	21	is	be	VBZ
cord-257662-viy65y72	347	22	supported	support	VBN
cord-257662-viy65y72	347	23	by	by	IN
cord-257662-viy65y72	347	24	NIH	NIH	NNP
cord-257662-viy65y72	347	25	-	-	HYPH
cord-257662-viy65y72	347	26	NIAID	NIAID	NNP
cord-257662-viy65y72	347	27	grants	grant	VBZ
cord-257662-viy65y72	347	28	U19	U19	NNP
cord-257662-viy65y72	347	29	AI109680	AI109680	NNP
cord-257662-viy65y72	347	30	and	and	CC
cord-257662-viy65y72	347	31	R01	R01	NNP
cord-257662-viy65y72	347	32	AI108725	AI108725	NNP
cord-257662-viy65y72	347	33	.	.	.
cord-257662-viy65y72	348	1	Kristina	Kristina	NNP
cord-257662-viy65y72	348	2	S.	S.	NNP
cord-257662-viy65y72	348	3	Burrack	Burrack	NNP
cord-257662-viy65y72	348	4	was	be	VBD
cord-257662-viy65y72	348	5	supported	support	VBN
cord-257662-viy65y72	348	6	by	by	IN
cord-257662-viy65y72	349	1	NIH	NIH	NNP
cord-257662-viy65y72	349	2	-	-	HYPH
cord-257662-viy65y72	349	3	NIAID	NIAID	NNP
cord-257662-viy65y72	349	4	training	training	NN
cord-257662-viy65y72	349	5	grant	grant	NN
cord-257662-viy65y72	349	6	T32	T32	NNP
cord-257662-viy65y72	349	7	AI052066	AI052066	NNP
cord-257662-viy65y72	349	8	.	.	.
cord-257662-viy65y72	350	1	The	the	DT
cord-257662-viy65y72	350	2	authors	author	NNS
cord-257662-viy65y72	350	3	declare	declare	VBP
cord-257662-viy65y72	350	4	that	that	IN
cord-257662-viy65y72	350	5	the	the	DT
cord-257662-viy65y72	350	6	research	research	NN
cord-257662-viy65y72	350	7	was	be	VBD
cord-257662-viy65y72	350	8	conducted	conduct	VBN
cord-257662-viy65y72	350	9	in	in	IN
cord-257662-viy65y72	350	10	the	the	DT
cord-257662-viy65y72	350	11	absence	absence	NN
cord-257662-viy65y72	350	12	of	of	IN
cord-257662-viy65y72	350	13	any	any	DT
cord-257662-viy65y72	350	14	commercial	commercial	JJ
cord-257662-viy65y72	350	15	or	or	CC
cord-257662-viy65y72	350	16	financial	financial	JJ
cord-257662-viy65y72	350	17	relationships	relationship	NNS
cord-257662-viy65y72	350	18	that	that	WDT
cord-257662-viy65y72	350	19	could	could	MD
cord-257662-viy65y72	350	20	be	be	VB
cord-257662-viy65y72	350	21	construed	construe	VBN
cord-257662-viy65y72	350	22	as	as	IN
cord-257662-viy65y72	350	23	a	a	DT
cord-257662-viy65y72	350	24	potential	potential	JJ
cord-257662-viy65y72	350	25	conflict	conflict	NN
cord-257662-viy65y72	350	26	of	of	IN
cord-257662-viy65y72	350	27	interest	interest	NN
cord-257662-viy65y72	350	28	.	.	.
cord-257662-viy65y72	350	29	 	 	_SP