id	sid	tid	token	lemma	pos
cord-010570-ytv7dwr0	1	1	key	key	JJ
cord-010570-ytv7dwr0	2	1	:	:	:
cord-010570-ytv7dwr0	2	2	cord-010570-ytv7dwr0	cord-010570-ytv7dwr0	NNS
cord-010570-ytv7dwr0	2	3	authors	author	NNS
cord-010570-ytv7dwr0	2	4	:	:	:
cord-010570-ytv7dwr0	2	5	Casadevall	Casadevall	NNP
cord-010570-ytv7dwr0	2	6	,	,	,
cord-010570-ytv7dwr0	2	7	Arturo	Arturo	NNP
cord-010570-ytv7dwr0	2	8	;	;	:
cord-010570-ytv7dwr0	2	9	Scharff	Scharff	NNP
cord-010570-ytv7dwr0	2	10	,	,	,
cord-010570-ytv7dwr0	2	11	Matthew	Matthew	NNP
cord-010570-ytv7dwr0	2	12	D.	D.	NNP
cord-010570-ytv7dwr0	2	13	title	title	NN
cord-010570-ytv7dwr0	2	14	:	:	:
cord-010570-ytv7dwr0	3	1	Return	return	VB
cord-010570-ytv7dwr0	3	2	to	to	IN
cord-010570-ytv7dwr0	3	3	the	the	DT
cord-010570-ytv7dwr0	3	4	Past	past	NN
cord-010570-ytv7dwr0	3	5	:	:	:
cord-010570-ytv7dwr0	4	1	The	the	DT
cord-010570-ytv7dwr0	4	2	Case	Case	NNP
cord-010570-ytv7dwr0	4	3	for	for	IN
cord-010570-ytv7dwr0	4	4	Antibody	Antibody	NNP
cord-010570-ytv7dwr0	4	5	-	-	HYPH
cord-010570-ytv7dwr0	4	6	Based	base	VBN
cord-010570-ytv7dwr0	4	7	Therapies	Therapies	NNPS
cord-010570-ytv7dwr0	4	8	in	in	IN
cord-010570-ytv7dwr0	4	9	Infectious	Infectious	NNP
cord-010570-ytv7dwr0	4	10	Diseases	Diseases	NNPS
cord-010570-ytv7dwr0	4	11	date	date	NN
cord-010570-ytv7dwr0	4	12	:	:	:
cord-010570-ytv7dwr0	4	13	1995	1995	CD
cord-010570-ytv7dwr0	4	14	-	-	HYPH
cord-010570-ytv7dwr0	4	15	07	07	CD
cord-010570-ytv7dwr0	4	16	-	-	SYM
cord-010570-ytv7dwr0	4	17	17	17	CD
cord-010570-ytv7dwr0	4	18	journal	journal	NN
cord-010570-ytv7dwr0	4	19	:	:	:
cord-010570-ytv7dwr0	5	1	Clin	Clin	NNP
cord-010570-ytv7dwr0	5	2	Infect	infect	VB
cord-010570-ytv7dwr0	5	3	Dis	Dis	NNP
cord-010570-ytv7dwr0	5	4	DOI	doi	NN
cord-010570-ytv7dwr0	5	5	:	:	:
cord-010570-ytv7dwr0	5	6	10.1093	10.1093	CD
cord-010570-ytv7dwr0	5	7	/	/	SYM
cord-010570-ytv7dwr0	5	8	clinids/21.1.150	clinids/21.1.150	NN
cord-010570-ytv7dwr0	5	9	sha	sha	NNP
cord-010570-ytv7dwr0	5	10	:	:	:
cord-010570-ytv7dwr0	5	11	af4043d17d0033fd6c0d4dd9107beb5a5aba4efd	af4043d17d0033fd6c0d4dd9107beb5a5aba4efd	IN
cord-010570-ytv7dwr0	5	12	doc_id	doc_id	CD
cord-010570-ytv7dwr0	5	13	:	:	:
cord-010570-ytv7dwr0	5	14	10570	10570	CD
cord-010570-ytv7dwr0	5	15	cord_uid	cord_uid	NNS
cord-010570-ytv7dwr0	5	16	:	:	:
cord-010570-ytv7dwr0	6	1	ytv7dwr0	ytv7dwr0	NNP
cord-010570-ytv7dwr0	7	1	In	in	IN
cord-010570-ytv7dwr0	7	2	the	the	DT
cord-010570-ytv7dwr0	7	3	preantibiotic	preantibiotic	JJ
cord-010570-ytv7dwr0	7	4	era	era	NN
cord-010570-ytv7dwr0	7	5	,	,	,
cord-010570-ytv7dwr0	7	6	passive	passive	JJ
cord-010570-ytv7dwr0	7	7	antibody	antibody	NNP
cord-010570-ytv7dwr0	7	8	administration	administration	NNP
cord-010570-ytv7dwr0	7	9	(	(	-LRB-
cord-010570-ytv7dwr0	7	10	serum	serum	NN
cord-010570-ytv7dwr0	7	11	therapy	therapy	NN
cord-010570-ytv7dwr0	7	12	)	)	-RRB-
cord-010570-ytv7dwr0	7	13	was	be	VBD
cord-010570-ytv7dwr0	7	14	useful	useful	JJ
cord-010570-ytv7dwr0	7	15	for	for	IN
cord-010570-ytv7dwr0	7	16	the	the	DT
cord-010570-ytv7dwr0	7	17	treatment	treatment	NN
cord-010570-ytv7dwr0	7	18	of	of	IN
cord-010570-ytv7dwr0	7	19	many	many	JJ
cord-010570-ytv7dwr0	7	20	infectious	infectious	JJ
cord-010570-ytv7dwr0	7	21	diseases	disease	NNS
cord-010570-ytv7dwr0	7	22	.	.	.
cord-010570-ytv7dwr0	8	1	The	the	DT
cord-010570-ytv7dwr0	8	2	introduction	introduction	NN
cord-010570-ytv7dwr0	8	3	of	of	IN
cord-010570-ytv7dwr0	8	4	antimicrobial	antimicrobial	JJ
cord-010570-ytv7dwr0	8	5	chemotherapy	chemotherapy	NN
cord-010570-ytv7dwr0	8	6	in	in	IN
cord-010570-ytv7dwr0	8	7	the	the	DT
cord-010570-ytv7dwr0	8	8	1940s	1940	NNS
cord-010570-ytv7dwr0	8	9	led	lead	VBD
cord-010570-ytv7dwr0	8	10	to	to	IN
cord-010570-ytv7dwr0	8	11	the	the	DT
cord-010570-ytv7dwr0	8	12	rapid	rapid	JJ
cord-010570-ytv7dwr0	8	13	abandonment	abandonment	NN
cord-010570-ytv7dwr0	8	14	of	of	IN
cord-010570-ytv7dwr0	8	15	many	many	JJ
cord-010570-ytv7dwr0	8	16	forms	form	NNS
cord-010570-ytv7dwr0	8	17	of	of	IN
cord-010570-ytv7dwr0	8	18	passive	passive	JJ
cord-010570-ytv7dwr0	8	19	antibody	antibody	NN
cord-010570-ytv7dwr0	8	20	therapy	therapy	NN
cord-010570-ytv7dwr0	8	21	.	.	.
cord-010570-ytv7dwr0	9	1	Chemotherapy	chemotherapy	NN
cord-010570-ytv7dwr0	9	2	was	be	VBD
cord-010570-ytv7dwr0	9	3	more	more	RBR
cord-010570-ytv7dwr0	9	4	effective	effective	JJ
cord-010570-ytv7dwr0	9	5	and	and	CC
cord-010570-ytv7dwr0	9	6	less	less	RBR
cord-010570-ytv7dwr0	9	7	toxic	toxic	JJ
cord-010570-ytv7dwr0	9	8	than	than	IN
cord-010570-ytv7dwr0	9	9	antibody	antibody	NN
cord-010570-ytv7dwr0	9	10	therapy	therapy	NN
cord-010570-ytv7dwr0	9	11	.	.	.
cord-010570-ytv7dwr0	10	1	In	in	IN
cord-010570-ytv7dwr0	10	2	this	this	DT
cord-010570-ytv7dwr0	10	3	last	last	JJ
cord-010570-ytv7dwr0	10	4	decade	decade	NN
cord-010570-ytv7dwr0	10	5	of	of	IN
cord-010570-ytv7dwr0	10	6	the	the	DT
cord-010570-ytv7dwr0	10	7	20th	20th	JJ
cord-010570-ytv7dwr0	10	8	century	century	NN
cord-010570-ytv7dwr0	10	9	the	the	DT
cord-010570-ytv7dwr0	10	10	efficacy	efficacy	NN
cord-010570-ytv7dwr0	10	11	of	of	IN
cord-010570-ytv7dwr0	10	12	antimicrobial	antimicrobial	JJ
cord-010570-ytv7dwr0	10	13	chemotherapy	chemotherapy	NN
cord-010570-ytv7dwr0	10	14	is	be	VBZ
cord-010570-ytv7dwr0	10	15	diminishing	diminish	VBG
cord-010570-ytv7dwr0	10	16	because	because	IN
cord-010570-ytv7dwr0	10	17	of	of	IN
cord-010570-ytv7dwr0	10	18	the	the	DT
cord-010570-ytv7dwr0	10	19	rapidly	rapidly	RB
cord-010570-ytv7dwr0	10	20	escalating	escalate	VBG
cord-010570-ytv7dwr0	10	21	number	number	NN
cord-010570-ytv7dwr0	10	22	of	of	IN
cord-010570-ytv7dwr0	10	23	immunocompromised	immunocompromised	JJ
cord-010570-ytv7dwr0	10	24	individuals	individual	NNS
cord-010570-ytv7dwr0	10	25	,	,	,
cord-010570-ytv7dwr0	10	26	the	the	DT
cord-010570-ytv7dwr0	10	27	emergence	emergence	NN
cord-010570-ytv7dwr0	10	28	of	of	IN
cord-010570-ytv7dwr0	10	29	new	new	JJ
cord-010570-ytv7dwr0	10	30	pathogens	pathogen	NNS
cord-010570-ytv7dwr0	10	31	,	,	,
cord-010570-ytv7dwr0	10	32	the	the	DT
cord-010570-ytv7dwr0	10	33	reemergence	reemergence	NN
cord-010570-ytv7dwr0	10	34	of	of	IN
cord-010570-ytv7dwr0	10	35	old	old	JJ
cord-010570-ytv7dwr0	10	36	pathogens	pathogen	NNS
cord-010570-ytv7dwr0	10	37	,	,	,
cord-010570-ytv7dwr0	10	38	and	and	CC
cord-010570-ytv7dwr0	10	39	widespread	widespread	JJ
cord-010570-ytv7dwr0	10	40	development	development	NN
cord-010570-ytv7dwr0	10	41	of	of	IN
cord-010570-ytv7dwr0	10	42	resistance	resistance	NN
cord-010570-ytv7dwr0	10	43	to	to	IN
cord-010570-ytv7dwr0	10	44	antimicrobial	antimicrobial	JJ
cord-010570-ytv7dwr0	10	45	drugs	drug	NNS
cord-010570-ytv7dwr0	10	46	.	.	.
cord-010570-ytv7dwr0	11	1	This	this	DT
cord-010570-ytv7dwr0	11	2	diminishment	diminishment	NN
cord-010570-ytv7dwr0	11	3	in	in	IN
cord-010570-ytv7dwr0	11	4	the	the	DT
cord-010570-ytv7dwr0	11	5	effectiveness	effectiveness	NN
cord-010570-ytv7dwr0	11	6	of	of	IN
cord-010570-ytv7dwr0	11	7	chemotherapy	chemotherapy	NN
cord-010570-ytv7dwr0	11	8	has	have	VBZ
cord-010570-ytv7dwr0	11	9	been	be	VBN
cord-010570-ytv7dwr0	11	10	paralleled	parallel	VBN
cord-010570-ytv7dwr0	11	11	by	by	IN
cord-010570-ytv7dwr0	11	12	advances	advance	NNS
cord-010570-ytv7dwr0	11	13	in	in	IN
cord-010570-ytv7dwr0	11	14	monoclonal	monoclonal	JJ
cord-010570-ytv7dwr0	11	15	antibody	antibody	NN
cord-010570-ytv7dwr0	11	16	technology	technology	NN
cord-010570-ytv7dwr0	11	17	that	that	WDT
cord-010570-ytv7dwr0	11	18	have	have	VBP
cord-010570-ytv7dwr0	11	19	made	make	VBN
cord-010570-ytv7dwr0	11	20	feasible	feasible	JJ
cord-010570-ytv7dwr0	11	21	the	the	DT
cord-010570-ytv7dwr0	11	22	generation	generation	NN
cord-010570-ytv7dwr0	11	23	of	of	IN
cord-010570-ytv7dwr0	11	24	human	human	JJ
cord-010570-ytv7dwr0	11	25	antibodies	antibody	NNS
cord-010570-ytv7dwr0	11	26	.	.	.
cord-010570-ytv7dwr0	12	1	This	this	DT
cord-010570-ytv7dwr0	12	2	combination	combination	NN
cord-010570-ytv7dwr0	12	3	of	of	IN
cord-010570-ytv7dwr0	12	4	factors	factor	NNS
cord-010570-ytv7dwr0	12	5	makes	make	VBZ
cord-010570-ytv7dwr0	12	6	passive	passive	JJ
cord-010570-ytv7dwr0	12	7	antibody	antibody	NN
cord-010570-ytv7dwr0	12	8	therapy	therapy	NN
cord-010570-ytv7dwr0	12	9	an	an	DT
cord-010570-ytv7dwr0	12	10	option	option	NN
cord-010570-ytv7dwr0	12	11	worthy	worthy	JJ
cord-010570-ytv7dwr0	12	12	of	of	IN
cord-010570-ytv7dwr0	12	13	serious	serious	JJ
cord-010570-ytv7dwr0	12	14	consideration	consideration	NN
cord-010570-ytv7dwr0	12	15	.	.	.
cord-010570-ytv7dwr0	13	1	We	-PRON-	PRP
cord-010570-ytv7dwr0	13	2	propose	propose	VBP
cord-010570-ytv7dwr0	13	3	that	that	IN
cord-010570-ytv7dwr0	13	4	for	for	IN
cord-010570-ytv7dwr0	13	5	every	every	DT
cord-010570-ytv7dwr0	13	6	pathogen	pathogen	NN
cord-010570-ytv7dwr0	13	7	there	there	EX
cord-010570-ytv7dwr0	13	8	exists	exist	VBZ
cord-010570-ytv7dwr0	13	9	an	an	DT
cord-010570-ytv7dwr0	13	10	antibody	antibody	NN
cord-010570-ytv7dwr0	13	11	that	that	WDT
cord-010570-ytv7dwr0	13	12	will	will	MD
cord-010570-ytv7dwr0	13	13	modify	modify	VB
cord-010570-ytv7dwr0	13	14	the	the	DT
cord-010570-ytv7dwr0	13	15	infection	infection	NN
cord-010570-ytv7dwr0	13	16	to	to	IN
cord-010570-ytv7dwr0	13	17	the	the	DT
cord-010570-ytv7dwr0	13	18	benefit	benefit	NN
cord-010570-ytv7dwr0	13	19	of	of	IN
cord-010570-ytv7dwr0	13	20	the	the	DT
cord-010570-ytv7dwr0	13	21	host	host	NN
cord-010570-ytv7dwr0	13	22	.	.	.
cord-010570-ytv7dwr0	14	1	Such	such	JJ
cord-010570-ytv7dwr0	14	2	antibodies	antibody	NNS
cord-010570-ytv7dwr0	14	3	are	be	VBP
cord-010570-ytv7dwr0	14	4	potential	potential	JJ
cord-010570-ytv7dwr0	14	5	antimicrobial	antimicrobial	JJ
cord-010570-ytv7dwr0	14	6	agents	agent	NNS
cord-010570-ytv7dwr0	14	7	.	.	.
cord-010570-ytv7dwr0	15	1	Antibody	antibody	NN
cord-010570-ytv7dwr0	15	2	-	-	HYPH
cord-010570-ytv7dwr0	15	3	based	base	VBN
cord-010570-ytv7dwr0	15	4	therapies	therapy	NNS
cord-010570-ytv7dwr0	15	5	have	have	VBP
cord-010570-ytv7dwr0	15	6	significant	significant	JJ
cord-010570-ytv7dwr0	15	7	advantages	advantage	NNS
cord-010570-ytv7dwr0	15	8	and	and	CC
cord-010570-ytv7dwr0	15	9	disadvantages	disadvantage	NNS
cord-010570-ytv7dwr0	15	10	relative	relative	JJ
cord-010570-ytv7dwr0	15	11	to	to	IN
cord-010570-ytv7dwr0	15	12	standard	standard	JJ
cord-010570-ytv7dwr0	15	13	chemotherapy	chemotherapy	NN
cord-010570-ytv7dwr0	15	14	.	.	.
cord-010570-ytv7dwr0	16	1	The	the	DT
cord-010570-ytv7dwr0	16	2	reintroduction	reintroduction	NN
cord-010570-ytv7dwr0	16	3	of	of	IN
cord-010570-ytv7dwr0	16	4	antibody	antibody	NN
cord-010570-ytv7dwr0	16	5	-	-	HYPH
cord-010570-ytv7dwr0	16	6	based	base	VBN
cord-010570-ytv7dwr0	16	7	therapy	therapy	NN
cord-010570-ytv7dwr0	16	8	would	would	MD
cord-010570-ytv7dwr0	16	9	require	require	VB
cord-010570-ytv7dwr0	16	10	major	major	JJ
cord-010570-ytv7dwr0	16	11	changes	change	NNS
cord-010570-ytv7dwr0	16	12	in	in	IN
cord-010570-ytv7dwr0	16	13	the	the	DT
cord-010570-ytv7dwr0	16	14	practices	practice	NNS
cord-010570-ytv7dwr0	16	15	of	of	IN
cord-010570-ytv7dwr0	16	16	infectious	infectious	JJ
cord-010570-ytv7dwr0	16	17	disease	disease	NN
cord-010570-ytv7dwr0	16	18	specialists	specialist	NNS
cord-010570-ytv7dwr0	16	19	.	.	.
cord-010570-ytv7dwr0	17	1	The	the	DT
cord-010570-ytv7dwr0	17	2	antibiotic	antibiotic	JJ
cord-010570-ytv7dwr0	17	3	era	era	NN
cord-010570-ytv7dwr0	17	4	is	be	VBZ
cord-010570-ytv7dwr0	17	5	about	about	RB
cord-010570-ytv7dwr0	17	6	60	60	CD
cord-010570-ytv7dwr0	17	7	years	year	NNS
cord-010570-ytv7dwr0	17	8	old	old	JJ
cord-010570-ytv7dwr0	17	9	.	.	.
cord-010570-ytv7dwr0	18	1	As	as	IN
cord-010570-ytv7dwr0	18	2	we	-PRON-	PRP
cord-010570-ytv7dwr0	18	3	approach	approach	VBP
cord-010570-ytv7dwr0	18	4	the	the	DT
cord-010570-ytv7dwr0	18	5	21st	21st	JJ
cord-010570-ytv7dwr0	18	6	century	century	NN
cord-010570-ytv7dwr0	18	7	,	,	,
cord-010570-ytv7dwr0	18	8	the	the	DT
cord-010570-ytv7dwr0	18	9	progress	progress	NN
cord-010570-ytv7dwr0	18	10	made	make	VBN
cord-010570-ytv7dwr0	18	11	in	in	IN
cord-010570-ytv7dwr0	18	12	controlling	control	VBG
cord-010570-ytv7dwr0	18	13	infections	infection	NNS
cord-010570-ytv7dwr0	18	14	is	be	VBZ
cord-010570-ytv7dwr0	18	15	threatened	threaten	VBN
cord-010570-ytv7dwr0	18	16	by	by	IN
cord-010570-ytv7dwr0	18	17	the	the	DT
cord-010570-ytv7dwr0	18	18	growing	grow	VBG
cord-010570-ytv7dwr0	18	19	numbers	number	NNS
cord-010570-ytv7dwr0	18	20	of	of	IN
cord-010570-ytv7dwr0	18	21	immunosuppressed	immunosuppressed	JJ
cord-010570-ytv7dwr0	18	22	individuals	individual	NNS
cord-010570-ytv7dwr0	18	23	;	;	:
cord-010570-ytv7dwr0	18	24	the	the	DT
cord-010570-ytv7dwr0	18	25	emergence	emergence	NN
cord-010570-ytv7dwr0	18	26	of	of	IN
cord-010570-ytv7dwr0	18	27	new	new	JJ
cord-010570-ytv7dwr0	18	28	pathogens	pathogen	NNS
cord-010570-ytv7dwr0	18	29	;	;	:
cord-010570-ytv7dwr0	18	30	the	the	DT
cord-010570-ytv7dwr0	18	31	reemergence	reemergence	NN
cord-010570-ytv7dwr0	18	32	of	of	IN
cord-010570-ytv7dwr0	18	33	old	old	JJ
cord-010570-ytv7dwr0	18	34	pathogens	pathogen	NNS
cord-010570-ytv7dwr0	18	35	;	;	:
cord-010570-ytv7dwr0	18	36	and	and	CC
cord-010570-ytv7dwr0	18	37	the	the	DT
cord-010570-ytv7dwr0	18	38	widespread	widespread	JJ
cord-010570-ytv7dwr0	18	39	resistance	resistance	NN
cord-010570-ytv7dwr0	18	40	of	of	IN
cord-010570-ytv7dwr0	18	41	organisms	organism	NNS
cord-010570-ytv7dwr0	18	42	to	to	IN
cord-010570-ytv7dwr0	18	43	antimicrobial	antimicrobial	JJ
cord-010570-ytv7dwr0	18	44	drugs	drug	NNS
cord-010570-ytv7dwr0	18	45	.	.	.
cord-010570-ytv7dwr0	19	1	Each	each	DT
cord-010570-ytv7dwr0	19	2	development	development	NN
cord-010570-ytv7dwr0	19	3	poses	pose	VBZ
cord-010570-ytv7dwr0	19	4	its	-PRON-	PRP$
cord-010570-ytv7dwr0	19	5	own	own	JJ
cord-010570-ytv7dwr0	19	6	set	set	NN
cord-010570-ytv7dwr0	19	7	of	of	IN
cord-010570-ytv7dwr0	19	8	challenges	challenge	NNS
cord-010570-ytv7dwr0	19	9	;	;	:
cord-010570-ytv7dwr0	19	10	in	in	IN
cord-010570-ytv7dwr0	19	11	combination	combination	NN
cord-010570-ytv7dwr0	19	12	,	,	,
cord-010570-ytv7dwr0	19	13	these	these	DT
cord-010570-ytv7dwr0	19	14	developments	development	NNS
cord-010570-ytv7dwr0	19	15	are	be	VBP
cord-010570-ytv7dwr0	19	16	already	already	RB
cord-010570-ytv7dwr0	19	17	undermining	undermine	VBG
cord-010570-ytv7dwr0	19	18	the	the	DT
cord-010570-ytv7dwr0	19	19	efficacy	efficacy	NN
cord-010570-ytv7dwr0	19	20	of	of	IN
cord-010570-ytv7dwr0	19	21	antimicrobial	antimicrobial	JJ
cord-010570-ytv7dwr0	19	22	chemotherapy	chemotherapy	NN
cord-010570-ytv7dwr0	19	23	.	.	.
cord-010570-ytv7dwr0	20	1	There	there	EX
cord-010570-ytv7dwr0	20	2	is	be	VBZ
cord-010570-ytv7dwr0	20	3	a	a	DT
cord-010570-ytv7dwr0	20	4	worldwide	worldwide	JJ
cord-010570-ytv7dwr0	20	5	epidemic	epidemic	NN
cord-010570-ytv7dwr0	20	6	of	of	IN
cord-010570-ytv7dwr0	20	7	immunosuppression	immunosuppression	NN
cord-010570-ytv7dwr0	20	8	due	due	IN
cord-010570-ytv7dwr0	20	9	to	to	IN
cord-010570-ytv7dwr0	20	10	malnutrition	malnutrition	NN
cord-010570-ytv7dwr0	20	11	,	,	,
cord-010570-ytv7dwr0	20	12	AIDS	AIDS	NNP
cord-010570-ytv7dwr0	20	13	,	,	,
cord-010570-ytv7dwr0	20	14	medical	medical	JJ
cord-010570-ytv7dwr0	20	15	therapies	therapy	NNS
cord-010570-ytv7dwr0	20	16	for	for	IN
cord-010570-ytv7dwr0	20	17	cancer	cancer	NN
cord-010570-ytv7dwr0	20	18	and	and	CC
cord-010570-ytv7dwr0	20	19	autoimmune	autoimmune	JJ
cord-010570-ytv7dwr0	20	20	diseases	disease	NNS
cord-010570-ytv7dwr0	20	21	,	,	,
cord-010570-ytv7dwr0	20	22	and	and	CC
cord-010570-ytv7dwr0	20	23	organ	organ	NN
cord-010570-ytv7dwr0	20	24	transplantation	transplantation	NN
cord-010570-ytv7dwr0	20	25	.	.	.
cord-010570-ytv7dwr0	21	1	Immunosuppressed	immunosuppressed	JJ
cord-010570-ytv7dwr0	21	2	hosts	host	NNS
cord-010570-ytv7dwr0	21	3	provide	provide	VBP
cord-010570-ytv7dwr0	21	4	ecological	ecological	JJ
cord-010570-ytv7dwr0	21	5	niches	niche	NNS
cord-010570-ytv7dwr0	21	6	for	for	IN
cord-010570-ytv7dwr0	21	7	low	low	JJ
cord-010570-ytv7dwr0	21	8	-	-	HYPH
cord-010570-ytv7dwr0	21	9	virulence	virulence	NN
cord-010570-ytv7dwr0	21	10	microorganisms	microorganism	NNS
cord-010570-ytv7dwr0	21	11	[	[	-LRB-
cord-010570-ytv7dwr0	21	12	1	1	CD
cord-010570-ytv7dwr0	21	13	]	]	-RRB-
cord-010570-ytv7dwr0	21	14	.	.	.
cord-010570-ytv7dwr0	22	1	In	in	IN
cord-010570-ytv7dwr0	22	2	addition	addition	NN
cord-010570-ytv7dwr0	22	3	,	,	,
cord-010570-ytv7dwr0	22	4	antimicrobial	antimicrobial	JJ
cord-010570-ytv7dwr0	22	5	drugs	drug	NNS
cord-010570-ytv7dwr0	22	6	are	be	VBP
cord-010570-ytv7dwr0	22	7	less	less	RBR
cord-010570-ytv7dwr0	22	8	effective	effective	JJ
cord-010570-ytv7dwr0	22	9	and	and	CC
cord-010570-ytv7dwr0	22	10	sometimes	sometimes	RB
cord-010570-ytv7dwr0	22	11	are	be	VBP
cord-010570-ytv7dwr0	22	12	unable	unable	JJ
cord-010570-ytv7dwr0	22	13	to	to	TO
cord-010570-ytv7dwr0	22	14	eradicate	eradicate	VB
cord-010570-ytv7dwr0	22	15	infection	infection	NN
cord-010570-ytv7dwr0	22	16	in	in	IN
cord-010570-ytv7dwr0	22	17	individuals	individual	NNS
cord-010570-ytv7dwr0	22	18	with	with	IN
cord-010570-ytv7dwr0	22	19	impaired	impaired	JJ
cord-010570-ytv7dwr0	22	20	immunity	immunity	NN
cord-010570-ytv7dwr0	22	21	.	.	.
cord-010570-ytv7dwr0	23	1	Classical	classical	JJ
cord-010570-ytv7dwr0	23	2	pathogens	pathogen	NNS
cord-010570-ytv7dwr0	23	3	such	such	JJ
cord-010570-ytv7dwr0	23	4	as	as	IN
cord-010570-ytv7dwr0	23	5	Mycobacterium	Mycobacterium	NNP
cord-010570-ytv7dwr0	23	6	tuberculosis	tuberculosis	NN
cord-010570-ytv7dwr0	23	7	and	and	CC
cord-010570-ytv7dwr0	23	8	Treponema	Treponema	NNP
cord-010570-ytv7dwr0	23	9	pallidum	pallidum	NN
cord-010570-ytv7dwr0	23	10	have	have	VBP
cord-010570-ytv7dwr0	23	11	reemerged	reemerge	VBN
cord-010570-ytv7dwr0	23	12	and	and	CC
cord-010570-ytv7dwr0	23	13	are	be	VBP
cord-010570-ytv7dwr0	23	14	difficult	difficult	JJ
cord-010570-ytv7dwr0	23	15	to	to	TO
cord-010570-ytv7dwr0	23	16	treat	treat	VB
cord-010570-ytv7dwr0	23	17	in	in	IN
cord-010570-ytv7dwr0	23	18	immunosuppressed	immunosuppressed	JJ
cord-010570-ytv7dwr0	23	19	individuals	individual	NNS
cord-010570-ytv7dwr0	23	20	[	[	-LRB-
cord-010570-ytv7dwr0	23	21	2	2	CD
cord-010570-ytv7dwr0	23	22	,	,	,
cord-010570-ytv7dwr0	23	23	3	3	CD
cord-010570-ytv7dwr0	23	24	]	]	-RRB-
cord-010570-ytv7dwr0	23	25	.	.	.
cord-010570-ytv7dwr0	24	1	The	the	DT
cord-010570-ytv7dwr0	24	2	increasing	increase	VBG
cord-010570-ytv7dwr0	24	3	frequency	frequency	NN
cord-010570-ytv7dwr0	24	4	of	of	IN
cord-010570-ytv7dwr0	24	5	drug	drug	NN
cord-010570-ytv7dwr0	24	6	-	-	HYPH
cord-010570-ytv7dwr0	24	7	resistant	resistant	JJ
cord-010570-ytv7dwr0	24	8	organisms	organism	NNS
cord-010570-ytv7dwr0	24	9	is	be	VBZ
cord-010570-ytv7dwr0	24	10	an	an	DT
cord-010570-ytv7dwr0	24	11	equally	equally	RB
cord-010570-ytv7dwr0	24	12	alarming	alarming	JJ
cord-010570-ytv7dwr0	24	13	development	development	NN
cord-010570-ytv7dwr0	24	14	,	,	,
cord-010570-ytv7dwr0	24	15	and	and	CC
cord-010570-ytv7dwr0	24	16	resistance	resistance	NN
cord-010570-ytv7dwr0	24	17	may	may	MD
cord-010570-ytv7dwr0	24	18	be	be	VB
cord-010570-ytv7dwr0	24	19	developing	develop	VBG
cord-010570-ytv7dwr0	24	20	faster	fast	RBR
cord-010570-ytv7dwr0	24	21	than	than	IN
cord-010570-ytv7dwr0	24	22	new	new	JJ
cord-010570-ytv7dwr0	24	23	antibiotics	antibiotic	NNS
cord-010570-ytv7dwr0	24	24	can	can	MD
cord-010570-ytv7dwr0	24	25	be	be	VB
cord-010570-ytv7dwr0	24	26	introduced	introduce	VBN
cord-010570-ytv7dwr0	24	27	[	[	-LRB-
cord-010570-ytv7dwr0	24	28	4	4	CD
cord-010570-ytv7dwr0	24	29	]	]	-RRB-
cord-010570-ytv7dwr0	24	30	.	.	.
cord-010570-ytv7dwr0	25	1	For	for	IN
cord-010570-ytv7dwr0	25	2	example	example	NN
cord-010570-ytv7dwr0	25	3	,	,	,
cord-010570-ytv7dwr0	25	4	in	in	IN
cord-010570-ytv7dwr0	25	5	one	one	CD
cord-010570-ytv7dwr0	25	6	New	New	NNP
cord-010570-ytv7dwr0	25	7	York	York	NNP
cord-010570-ytv7dwr0	25	8	City	City	NNP
cord-010570-ytv7dwr0	25	9	hospital	hospital	NN
cord-010570-ytv7dwr0	25	10	,	,	,
cord-010570-ytv7dwr0	25	11	the	the	DT
cord-010570-ytv7dwr0	25	12	percentage	percentage	NN
cord-010570-ytv7dwr0	25	13	of	of	IN
cord-010570-ytv7dwr0	25	14	vancomycinsusceptible	vancomycinsusceptible	JJ
cord-010570-ytv7dwr0	25	15	Enterococcus	Enterococcus	NNP
cord-010570-ytv7dwr0	25	16	faecium	faecium	NN
cord-010570-ytv7dwr0	25	17	decreased	decrease	VBD
cord-010570-ytv7dwr0	25	18	from	from	IN
cord-010570-ytv7dwr0	25	19	86	86	CD
cord-010570-ytv7dwr0	25	20	%	%	NN
cord-010570-ytv7dwr0	25	21	to	to	IN
cord-010570-ytv7dwr0	25	22	26	26	CD
cord-010570-ytv7dwr0	25	23	%	%	NN
cord-010570-ytv7dwr0	25	24	in	in	IN
cord-010570-ytv7dwr0	25	25	2	2	CD
cord-010570-ytv7dwr0	25	26	years	year	NNS
cord-010570-ytv7dwr0	25	27	[	[	-LRB-
cord-010570-ytv7dwr0	25	28	5	5	CD
cord-010570-ytv7dwr0	25	29	]	]	-RRB-
cord-010570-ytv7dwr0	25	30	.	.	.
cord-010570-ytv7dwr0	26	1	The	the	DT
cord-010570-ytv7dwr0	26	2	problem	problem	NN
cord-010570-ytv7dwr0	26	3	of	of	IN
cord-010570-ytv7dwr0	26	4	resistance	resistance	NN
cord-010570-ytv7dwr0	26	5	is	be	VBZ
cord-010570-ytv7dwr0	26	6	not	not	RB
cord-010570-ytv7dwr0	26	7	limited	limit	VBN
cord-010570-ytv7dwr0	26	8	to	to	IN
cord-010570-ytv7dwr0	26	9	bacteria	bacteria	NNS
cord-010570-ytv7dwr0	26	10	;	;	:
cord-010570-ytv7dwr0	26	11	there	there	EX
cord-010570-ytv7dwr0	26	12	are	be	VBP
cord-010570-ytv7dwr0	26	13	numerous	numerous	JJ
cord-010570-ytv7dwr0	26	14	reports	report	NNS
cord-010570-ytv7dwr0	26	15	of	of	IN
cord-010570-ytv7dwr0	26	16	fluconazole	fluconazole	NN
cord-010570-ytv7dwr0	26	17	-	-	HYPH
cord-010570-ytv7dwr0	26	18	resistant	resistant	JJ
cord-010570-ytv7dwr0	26	19	Candida	Candida	NNP
cord-010570-ytv7dwr0	26	20	albicans	albican	NNS
cord-010570-ytv7dwr0	26	21	[	[	-LRB-
cord-010570-ytv7dwr0	26	22	6	6	CD
cord-010570-ytv7dwr0	26	23	]	]	-RRB-
cord-010570-ytv7dwr0	26	24	.	.	.
cord-010570-ytv7dwr0	27	1	We	-PRON-	PRP
cord-010570-ytv7dwr0	27	2	briefly	briefly	RB
cord-010570-ytv7dwr0	27	3	review	review	VBP
cord-010570-ytv7dwr0	27	4	the	the	DT
cord-010570-ytv7dwr0	27	5	use	use	NN
cord-010570-ytv7dwr0	27	6	of	of	IN
cord-010570-ytv7dwr0	27	7	antibody	antibody	NN
cord-010570-ytv7dwr0	27	8	-	-	HYPH
cord-010570-ytv7dwr0	27	9	based	base	VBN
cord-010570-ytv7dwr0	27	10	therapy	therapy	NN
cord-010570-ytv7dwr0	27	11	in	in	IN
cord-010570-ytv7dwr0	27	12	the	the	DT
cord-010570-ytv7dwr0	27	13	early	early	JJ
cord-010570-ytv7dwr0	27	14	20th	20th	JJ
cord-010570-ytv7dwr0	27	15	century	century	NN
cord-010570-ytv7dwr0	27	16	and	and	CC
cord-010570-ytv7dwr0	27	17	make	make	VB
cord-010570-ytv7dwr0	27	18	the	the	DT
cord-010570-ytv7dwr0	27	19	case	case	NN
cord-010570-ytv7dwr0	27	20	for	for	IN
cord-010570-ytv7dwr0	27	21	reintroducing	reintroduce	VBG
cord-010570-ytv7dwr0	27	22	passive	passive	JJ
cord-010570-ytv7dwr0	27	23	antibody	antibody	NNP
cord-010570-ytv7dwr0	27	24	administration	administration	NN
cord-010570-ytv7dwr0	27	25	for	for	IN
cord-010570-ytv7dwr0	27	26	the	the	DT
cord-010570-ytv7dwr0	27	27	treatment	treatment	NN
cord-010570-ytv7dwr0	27	28	ofinfectious	ofinfectious	JJ
cord-010570-ytv7dwr0	27	29	diseases	disease	NNS
cord-010570-ytv7dwr0	27	30	.	.	.
cord-010570-ytv7dwr0	28	1	Advances	advance	NNS
cord-010570-ytv7dwr0	28	2	in	in	IN
cord-010570-ytv7dwr0	28	3	monoclonal	monoclonal	JJ
cord-010570-ytv7dwr0	28	4	antibody	antibody	NN
cord-010570-ytv7dwr0	28	5	(	(	-LRB-
cord-010570-ytv7dwr0	28	6	mAb	mAb	NNS
cord-010570-ytv7dwr0	28	7	)	)	-RRB-
cord-010570-ytv7dwr0	28	8	technology	technology	NN
cord-010570-ytv7dwr0	28	9	provide	provide	VBP
cord-010570-ytv7dwr0	28	10	new	new	JJ
cord-010570-ytv7dwr0	28	11	opportunities	opportunity	NNS
cord-010570-ytv7dwr0	28	12	for	for	IN
cord-010570-ytv7dwr0	28	13	developing	develop	VBG
cord-010570-ytv7dwr0	28	14	antibody	antibody	NN
cord-010570-ytv7dwr0	28	15	-	-	HYPH
cord-010570-ytv7dwr0	28	16	based	base	VBN
cord-010570-ytv7dwr0	28	17	therapies	therapy	NNS
cord-010570-ytv7dwr0	28	18	.	.	.
cord-010570-ytv7dwr0	29	1	In	in	IN
cord-010570-ytv7dwr0	29	2	the	the	DT
cord-010570-ytv7dwr0	29	3	case	case	NN
cord-010570-ytv7dwr0	29	4	of	of	IN
cord-010570-ytv7dwr0	29	5	pathogens	pathogen	NNS
cord-010570-ytv7dwr0	29	6	for	for	IN
cord-010570-ytv7dwr0	29	7	which	which	WDT
cord-010570-ytv7dwr0	29	8	antimicrobial	antimicrobial	JJ
cord-010570-ytv7dwr0	29	9	chemotherapy	chemotherapy	NN
cord-010570-ytv7dwr0	29	10	already	already	RB
cord-010570-ytv7dwr0	29	11	exists	exist	VBZ
cord-010570-ytv7dwr0	29	12	,	,	,
cord-010570-ytv7dwr0	29	13	antibody	antibody	NN
cord-010570-ytv7dwr0	29	14	-	-	HYPH
cord-010570-ytv7dwr0	29	15	based	base	VBN
cord-010570-ytv7dwr0	29	16	therapies	therapy	NNS
cord-010570-ytv7dwr0	29	17	could	could	MD
cord-010570-ytv7dwr0	29	18	be	be	VB
cord-010570-ytv7dwr0	29	19	used	use	VBN
cord-010570-ytv7dwr0	29	20	with	with	IN
cord-010570-ytv7dwr0	29	21	existing	exist	VBG
cord-010570-ytv7dwr0	29	22	chemotherapy	chemotherapy	NN
cord-010570-ytv7dwr0	29	23	to	to	TO
cord-010570-ytv7dwr0	29	24	improve	improve	VB
cord-010570-ytv7dwr0	29	25	outcome	outcome	NN
cord-010570-ytv7dwr0	29	26	and	and	CC
cord-010570-ytv7dwr0	29	27	possibly	possibly	RB
cord-010570-ytv7dwr0	29	28	reduce	reduce	VB
cord-010570-ytv7dwr0	29	29	the	the	DT
cord-010570-ytv7dwr0	29	30	development	development	NN
cord-010570-ytv7dwr0	29	31	of	of	IN
cord-010570-ytv7dwr0	29	32	resistance	resistance	NN
cord-010570-ytv7dwr0	29	33	.	.	.
cord-010570-ytv7dwr0	30	1	In	in	IN
cord-010570-ytv7dwr0	30	2	the	the	DT
cord-010570-ytv7dwr0	30	3	case	case	NN
cord-010570-ytv7dwr0	30	4	of	of	IN
cord-010570-ytv7dwr0	30	5	pathogens	pathogen	NNS
cord-010570-ytv7dwr0	30	6	for	for	IN
cord-010570-ytv7dwr0	30	7	which	which	WDT
cord-010570-ytv7dwr0	30	8	no	no	DT
cord-010570-ytv7dwr0	30	9	effective	effective	JJ
cord-010570-ytv7dwr0	30	10	chemotherapy	chemotherapy	NN
cord-010570-ytv7dwr0	30	11	exists	exist	VBZ
cord-010570-ytv7dwr0	30	12	,	,	,
cord-010570-ytv7dwr0	30	13	antibody	antibody	NN
cord-010570-ytv7dwr0	30	14	-	-	HYPH
cord-010570-ytv7dwr0	30	15	based	base	VBN
cord-010570-ytv7dwr0	30	16	therapies	therapy	NNS
cord-010570-ytv7dwr0	30	17	could	could	MD
cord-010570-ytv7dwr0	30	18	be	be	VB
cord-010570-ytv7dwr0	30	19	used	use	VBN
cord-010570-ytv7dwr0	30	20	for	for	IN
cord-010570-ytv7dwr0	30	21	primary	primary	JJ
cord-010570-ytv7dwr0	30	22	therapy	therapy	NN
cord-010570-ytv7dwr0	30	23	.	.	.
cord-010570-ytv7dwr0	31	1	Given	give	VBN
cord-010570-ytv7dwr0	31	2	the	the	DT
cord-010570-ytv7dwr0	31	3	diminishing	diminish	VBG
cord-010570-ytv7dwr0	31	4	efficacy	efficacy	NN
cord-010570-ytv7dwr0	31	5	of	of	IN
cord-010570-ytv7dwr0	31	6	existing	exist	VBG
cord-010570-ytv7dwr0	31	7	antimicrobials	antimicrobial	NNS
cord-010570-ytv7dwr0	31	8	because	because	IN
cord-010570-ytv7dwr0	31	9	of	of	IN
cord-010570-ytv7dwr0	31	10	widespread	widespread	JJ
cord-010570-ytv7dwr0	31	11	resistance	resistance	NN
cord-010570-ytv7dwr0	31	12	and	and	CC
cord-010570-ytv7dwr0	31	13	the	the	DT
cord-010570-ytv7dwr0	31	14	difficulties	difficulty	NNS
cord-010570-ytv7dwr0	31	15	of	of	IN
cord-010570-ytv7dwr0	31	16	treating	treat	VBG
cord-010570-ytv7dwr0	31	17	infections	infection	NNS
cord-010570-ytv7dwr0	31	18	in	in	IN
cord-010570-ytv7dwr0	31	19	immunosuppressed	immunosuppressed	JJ
cord-010570-ytv7dwr0	31	20	individuals	individual	NNS
cord-010570-ytv7dwr0	31	21	,	,	,
cord-010570-ytv7dwr0	31	22	the	the	DT
cord-010570-ytv7dwr0	31	23	reintroduction	reintroduction	NN
cord-010570-ytv7dwr0	31	24	of	of	IN
cord-010570-ytv7dwr0	31	25	antibody	antibody	NN
cord-010570-ytv7dwr0	31	26	-	-	HYPH
cord-010570-ytv7dwr0	31	27	based	base	VBN
cord-010570-ytv7dwr0	31	28	therapies	therapy	NNS
cord-010570-ytv7dwr0	31	29	is	be	VBZ
cord-010570-ytv7dwr0	31	30	an	an	DT
cord-010570-ytv7dwr0	31	31	option	option	NN
cord-010570-ytv7dwr0	31	32	that	that	WDT
cord-010570-ytv7dwr0	31	33	should	should	MD
cord-010570-ytv7dwr0	31	34	be	be	VB
cord-010570-ytv7dwr0	31	35	given	give	VBN
cord-010570-ytv7dwr0	31	36	serious	serious	JJ
cord-010570-ytv7dwr0	31	37	consideration	consideration	NN
cord-010570-ytv7dwr0	31	38	.	.	.
cord-010570-ytv7dwr0	32	1	This	this	DT
cord-010570-ytv7dwr0	32	2	reintroduction	reintroduction	NN
cord-010570-ytv7dwr0	32	3	would	would	MD
cord-010570-ytv7dwr0	32	4	require	require	VB
cord-010570-ytv7dwr0	32	5	major	major	JJ
cord-010570-ytv7dwr0	32	6	changes	change	NNS
cord-010570-ytv7dwr0	32	7	in	in	IN
cord-010570-ytv7dwr0	32	8	the	the	DT
cord-010570-ytv7dwr0	32	9	practice	practice	NN
cord-010570-ytv7dwr0	32	10	of	of	IN
cord-010570-ytv7dwr0	32	11	infectious	infectious	JJ
cord-010570-ytv7dwr0	32	12	disease	disease	NN
cord-010570-ytv7dwr0	32	13	medicine	medicine	NN
cord-010570-ytv7dwr0	32	14	.	.	.
cord-010570-ytv7dwr0	33	1	The	the	DT
cord-010570-ytv7dwr0	33	2	administration	administration	NN
cord-010570-ytv7dwr0	33	3	of	of	IN
cord-010570-ytv7dwr0	33	4	immune	immune	JJ
cord-010570-ytv7dwr0	33	5	serum	serum	NN
cord-010570-ytv7dwr0	33	6	(	(	-LRB-
cord-010570-ytv7dwr0	33	7	usually	usually	RB
cord-010570-ytv7dwr0	33	8	animal	animal	NN
cord-010570-ytv7dwr0	33	9	)	)	-RRB-
cord-010570-ytv7dwr0	33	10	for	for	IN
cord-010570-ytv7dwr0	33	11	the	the	DT
cord-010570-ytv7dwr0	33	12	treatment	treatment	NN
cord-010570-ytv7dwr0	33	13	of	of	IN
cord-010570-ytv7dwr0	33	14	infections	infection	NNS
cord-010570-ytv7dwr0	33	15	was	be	VBD
cord-010570-ytv7dwr0	33	16	called	call	VBN
cord-010570-ytv7dwr0	33	17	serum	serum	NN
cord-010570-ytv7dwr0	33	18	therapy	therapy	NN
cord-010570-ytv7dwr0	33	19	and	and	CC
cord-010570-ytv7dwr0	33	20	was	be	VBD
cord-010570-ytv7dwr0	33	21	introduced	introduce	VBN
cord-010570-ytv7dwr0	33	22	in	in	IN
cord-010570-ytv7dwr0	33	23	the	the	DT
cord-010570-ytv7dwr0	33	24	1890s	1890	NNS
cord-010570-ytv7dwr0	33	25	for	for	IN
cord-010570-ytv7dwr0	33	26	the	the	DT
cord-010570-ytv7dwr0	33	27	treatment	treatment	NN
cord-010570-ytv7dwr0	33	28	of	of	IN
cord-010570-ytv7dwr0	33	29	diphtheria	diphtheria	NN
cord-010570-ytv7dwr0	33	30	.	.	.
cord-010570-ytv7dwr0	34	1	By	by	IN
cord-010570-ytv7dwr0	34	2	the	the	DT
cord-010570-ytv7dwr0	34	3	1930s	1930	NNS
cord-010570-ytv7dwr0	34	4	,	,	,
cord-010570-ytv7dwr0	34	5	serum	serum	NN
cord-010570-ytv7dwr0	34	6	therapy	therapy	NN
cord-010570-ytv7dwr0	34	7	was	be	VBD
cord-010570-ytv7dwr0	34	8	widely	widely	RB
cord-010570-ytv7dwr0	34	9	used	use	VBN
cord-010570-ytv7dwr0	34	10	for	for	IN
cord-010570-ytv7dwr0	34	11	the	the	DT
cord-010570-ytv7dwr0	34	12	treatment	treatment	NN
cord-010570-ytv7dwr0	34	13	of	of	IN
cord-010570-ytv7dwr0	34	14	Table	Table	NNP
cord-010570-ytv7dwr0	34	15	1	1	CD
cord-010570-ytv7dwr0	34	16	.	.	.
cord-010570-ytv7dwr0	35	1	Infectious	infectious	JJ
cord-010570-ytv7dwr0	35	2	diseases	disease	NNS
cord-010570-ytv7dwr0	35	3	that	that	WDT
cord-010570-ytv7dwr0	35	4	were	be	VBD
cord-010570-ytv7dwr0	35	5	treated	treat	VBN
cord-010570-ytv7dwr0	35	6	with	with	IN
cord-010570-ytv7dwr0	35	7	antibody	antibody	NN
cord-010570-ytv7dwr0	35	8	-	-	HYPH
cord-010570-ytv7dwr0	35	9	based	base	VBN
cord-010570-ytv7dwr0	35	10	therapies	therapy	NNS
cord-010570-ytv7dwr0	35	11	in	in	IN
cord-010570-ytv7dwr0	35	12	the	the	DT
cord-010570-ytv7dwr0	35	13	preantibiotic	preantibiotic	JJ
cord-010570-ytv7dwr0	35	14	era	era	NN
cord-010570-ytv7dwr0	35	15	.	.	.
cord-010570-ytv7dwr0	36	1	bacterial	bacterial	JJ
cord-010570-ytv7dwr0	36	2	and	and	CC
cord-010570-ytv7dwr0	36	3	viral	viral	JJ
cord-010570-ytv7dwr0	36	4	infections	infection	NNS
cord-010570-ytv7dwr0	36	5	(	(	-LRB-
cord-010570-ytv7dwr0	36	6	table	table	NN
cord-010570-ytv7dwr0	36	7	1	1	CD
cord-010570-ytv7dwr0	36	8	)	)	-RRB-
cord-010570-ytv7dwr0	36	9	.	.	.
cord-010570-ytv7dwr0	37	1	For	for	IN
cord-010570-ytv7dwr0	37	2	example	example	NN
cord-010570-ytv7dwr0	37	3	,	,	,
cord-010570-ytv7dwr0	37	4	in	in	IN
cord-010570-ytv7dwr0	37	5	the	the	DT
cord-010570-ytv7dwr0	37	6	late	late	JJ
cord-010570-ytv7dwr0	37	7	1930s	1930	NNS
cord-010570-ytv7dwr0	37	8	,	,	,
cord-010570-ytv7dwr0	37	9	86	86	CD
cord-010570-ytv7dwr0	37	10	%	%	NN
cord-010570-ytv7dwr0	37	11	of	of	IN
cord-010570-ytv7dwr0	37	12	patients	patient	NNS
cord-010570-ytv7dwr0	37	13	with	with	IN
cord-010570-ytv7dwr0	37	14	type	type	NN
cord-010570-ytv7dwr0	38	1	I	-PRON-	PRP
cord-010570-ytv7dwr0	38	2	pneumococcal	pneumococcal	JJ
cord-010570-ytv7dwr0	38	3	pneumonia	pneumonia	NN
cord-010570-ytv7dwr0	38	4	admitted	admit	VBD
cord-010570-ytv7dwr0	38	5	to	to	IN
cord-010570-ytv7dwr0	38	6	Boston	Boston	NNP
cord-010570-ytv7dwr0	38	7	City	City	NNP
cord-010570-ytv7dwr0	38	8	Hospital	Hospital	NNP
cord-010570-ytv7dwr0	38	9	were	be	VBD
cord-010570-ytv7dwr0	38	10	treated	treat	VBN
cord-010570-ytv7dwr0	38	11	with	with	IN
cord-010570-ytv7dwr0	38	12	type	type	NN
cord-010570-ytv7dwr0	38	13	-	-	HYPH
cord-010570-ytv7dwr0	38	14	specific	specific	JJ
cord-010570-ytv7dwr0	38	15	serum	serum	NN
cord-010570-ytv7dwr0	38	16	[	[	-LRB-
cord-010570-ytv7dwr0	38	17	36	36	CD
cord-010570-ytv7dwr0	38	18	]	]	-RRB-
cord-010570-ytv7dwr0	38	19	.	.	.
cord-010570-ytv7dwr0	39	1	From	from	IN
cord-010570-ytv7dwr0	39	2	1927	1927	CD
cord-010570-ytv7dwr0	39	3	to	to	IN
cord-010570-ytv7dwr0	39	4	1932	1932	CD
cord-010570-ytv7dwr0	39	5	at	at	IN
cord-010570-ytv7dwr0	39	6	Bellevue	Bellevue	NNP
cord-010570-ytv7dwr0	39	7	Hospital	Hospital	NNP
cord-010570-ytv7dwr0	39	8	(	(	-LRB-
cord-010570-ytv7dwr0	39	9	New	New	NNP
cord-010570-ytv7dwr0	39	10	York	York	NNP
cord-010570-ytv7dwr0	39	11	)	)	-RRB-
cord-010570-ytv7dwr0	39	12	,	,	,
cord-010570-ytv7dwr0	39	13	>	>	XX
cord-010570-ytv7dwr0	39	14	3,000	3,000	CD
cord-010570-ytv7dwr0	39	15	patients	patient	NNS
cord-010570-ytv7dwr0	39	16	with	with	IN
cord-010570-ytv7dwr0	39	17	erysipelas	erysipela	NNS
cord-010570-ytv7dwr0	39	18	were	be	VBD
cord-010570-ytv7dwr0	39	19	treated	treat	VBN
cord-010570-ytv7dwr0	39	20	with	with	IN
cord-010570-ytv7dwr0	39	21	serum	serum	NN
cord-010570-ytv7dwr0	39	22	[	[	-LRB-
cord-010570-ytv7dwr0	39	23	37	37	CD
cord-010570-ytv7dwr0	39	24	]	]	-RRB-
cord-010570-ytv7dwr0	39	25	(	(	-LRB-
cord-010570-ytv7dwr0	39	26	figure	figure	NN
cord-010570-ytv7dwr0	39	27	1	1	CD
cord-010570-ytv7dwr0	39	28	)	)	-RRB-
cord-010570-ytv7dwr0	39	29	.	.	.
cord-010570-ytv7dwr0	40	1	The	the	DT
cord-010570-ytv7dwr0	40	2	efficacy	efficacy	NN
cord-010570-ytv7dwr0	40	3	of	of	IN
cord-010570-ytv7dwr0	40	4	serum	serum	NN
cord-010570-ytv7dwr0	40	5	therapy	therapy	NN
cord-010570-ytv7dwr0	40	6	varied	vary	VBN
cord-010570-ytv7dwr0	40	7	with	with	IN
cord-010570-ytv7dwr0	40	8	the	the	DT
cord-010570-ytv7dwr0	40	9	type	type	NN
cord-010570-ytv7dwr0	40	10	or	or	CC
cord-010570-ytv7dwr0	40	11	severity	severity	NN
cord-010570-ytv7dwr0	40	12	of	of	IN
cord-010570-ytv7dwr0	40	13	infection	infection	NN
cord-010570-ytv7dwr0	40	14	.	.	.
cord-010570-ytv7dwr0	41	1	Several	several	JJ
cord-010570-ytv7dwr0	41	2	large	large	JJ
cord-010570-ytv7dwr0	41	3	controlled	control	VBN
cord-010570-ytv7dwr0	41	4	studies	study	NNS
cord-010570-ytv7dwr0	41	5	revealed	reveal	VBD
cord-010570-ytv7dwr0	41	6	that	that	IN
cord-010570-ytv7dwr0	41	7	type	type	NN
cord-010570-ytv7dwr0	41	8	-	-	HYPH
cord-010570-ytv7dwr0	41	9	specific	specific	JJ
cord-010570-ytv7dwr0	41	10	serum	serum	NN
cord-010570-ytv7dwr0	41	11	reduced	reduce	VBD
cord-010570-ytv7dwr0	41	12	the	the	DT
cord-010570-ytv7dwr0	41	13	mortality	mortality	NN
cord-010570-ytv7dwr0	41	14	ofpneumococcal	ofpneumococcal	JJ
cord-010570-ytv7dwr0	41	15	pneumonia	pneumonia	NN
cord-010570-ytv7dwr0	41	16	[	[	-LRB-
cord-010570-ytv7dwr0	41	17	7	7	CD
cord-010570-ytv7dwr0	41	18	]	]	-RRB-
cord-010570-ytv7dwr0	41	19	.	.	.
cord-010570-ytv7dwr0	42	1	Serum	serum	NN
cord-010570-ytv7dwr0	42	2	therapy	therapy	NN
cord-010570-ytv7dwr0	42	3	also	also	RB
cord-010570-ytv7dwr0	42	4	appears	appear	VBZ
cord-010570-ytv7dwr0	42	5	to	to	TO
cord-010570-ytv7dwr0	42	6	have	have	VB
cord-010570-ytv7dwr0	42	7	significantly	significantly	RB
cord-010570-ytv7dwr0	42	8	reduced	reduce	VBN
cord-010570-ytv7dwr0	42	9	mortality	mortality	NN
cord-010570-ytv7dwr0	42	10	due	due	IN
cord-010570-ytv7dwr0	42	11	to	to	IN
cord-010570-ytv7dwr0	42	12	meningococcal	meningococcal	JJ
cord-010570-ytv7dwr0	42	13	meningitis	meningitis	NN
cord-010570-ytv7dwr0	42	14	in	in	IN
cord-010570-ytv7dwr0	42	15	some	some	DT
cord-010570-ytv7dwr0	42	16	epidemics	epidemic	NNS
cord-010570-ytv7dwr0	42	17	[	[	-LRB-
cord-010570-ytv7dwr0	42	18	7	7	CD
cord-010570-ytv7dwr0	42	19	,	,	,
cord-010570-ytv7dwr0	42	20	38	38	CD
cord-010570-ytv7dwr0	42	21	]	]	-RRB-
cord-010570-ytv7dwr0	42	22	.	.	.
cord-010570-ytv7dwr0	43	1	Serum	serum	NN
cord-010570-ytv7dwr0	43	2	therapy	therapy	NN
cord-010570-ytv7dwr0	43	3	reduced	reduce	VBD
cord-010570-ytv7dwr0	43	4	mortality	mortality	NN
cord-010570-ytv7dwr0	43	5	due	due	IN
cord-010570-ytv7dwr0	43	6	to	to	IN
cord-010570-ytv7dwr0	43	7	Haemophilus	Haemophilus	NNP
cord-010570-ytv7dwr0	43	8	irif	irif	NN
cord-010570-ytv7dwr0	43	9	/	/	SYM
cord-010570-ytv7dwr0	43	10	uenzae	uenzae	NN
cord-010570-ytv7dwr0	43	11	meningitis	meningitis	NN
cord-010570-ytv7dwr0	43	12	,	,	,
cord-010570-ytv7dwr0	43	13	but	but	CC
cord-010570-ytv7dwr0	43	14	the	the	DT
cord-010570-ytv7dwr0	43	15	effect	effect	NN
cord-010570-ytv7dwr0	43	16	was	be	VBD
cord-010570-ytv7dwr0	43	17	small	small	JJ
cord-010570-ytv7dwr0	43	18	[	[	-LRB-
cord-010570-ytv7dwr0	43	19	8	8	CD
cord-010570-ytv7dwr0	43	20	]	]	-RRB-
cord-010570-ytv7dwr0	43	21	[	[	-LRB-
cord-010570-ytv7dwr0	43	22	9	9	CD
cord-010570-ytv7dwr0	43	23	]	]	-RRB-
cord-010570-ytv7dwr0	43	24	[	[	-LRB-
cord-010570-ytv7dwr0	43	25	10	10	CD
cord-010570-ytv7dwr0	43	26	]	]	-RRB-
cord-010570-ytv7dwr0	43	27	.	.	.
cord-010570-ytv7dwr0	44	1	Serum	serum	NN
cord-010570-ytv7dwr0	44	2	therapy	therapy	NN
cord-010570-ytv7dwr0	44	3	for	for	IN
cord-010570-ytv7dwr0	44	4	erysipelas	erysipela	NNS
cord-010570-ytv7dwr0	44	5	reduced	reduce	VBN
cord-010570-ytv7dwr0	44	6	mortality	mortality	NN
cord-010570-ytv7dwr0	44	7	in	in	IN
cord-010570-ytv7dwr0	44	8	comparison	comparison	NN
cord-010570-ytv7dwr0	44	9	to	to	IN
cord-010570-ytv7dwr0	44	10	historical	historical	JJ
cord-010570-ytv7dwr0	44	11	controls	control	NNS
cord-010570-ytv7dwr0	44	12	[	[	-LRB-
cord-010570-ytv7dwr0	44	13	37	37	CD
cord-010570-ytv7dwr0	44	14	,	,	,
cord-010570-ytv7dwr0	44	15	39	39	CD
cord-010570-ytv7dwr0	44	16	]	]	-RRB-
cord-010570-ytv7dwr0	44	17	.	.	.
cord-010570-ytv7dwr0	45	1	Serum	serum	NN
cord-010570-ytv7dwr0	45	2	therapy	therapy	NN
cord-010570-ytv7dwr0	45	3	reduced	reduce	VBD
cord-010570-ytv7dwr0	45	4	mortality	mortality	NN
cord-010570-ytv7dwr0	45	5	in	in	IN
cord-010570-ytv7dwr0	45	6	diphtheria	diphtheria	NN
cord-010570-ytv7dwr0	45	7	,	,	,
cord-010570-ytv7dwr0	45	8	and	and	CC
cord-010570-ytv7dwr0	45	9	antibody	antibody	NN
cord-010570-ytv7dwr0	45	10	therapy	therapy	NN
cord-010570-ytv7dwr0	45	11	continues	continue	VBZ
cord-010570-ytv7dwr0	45	12	to	to	TO
cord-010570-ytv7dwr0	45	13	be	be	VB
cord-010570-ytv7dwr0	45	14	used	use	VBN
cord-010570-ytv7dwr0	45	15	today	today	NN
cord-010570-ytv7dwr0	45	16	to	to	TO
cord-010570-ytv7dwr0	45	17	treat	treat	VB
cord-010570-ytv7dwr0	45	18	this	this	DT
cord-010570-ytv7dwr0	45	19	disease	disease	NN
cord-010570-ytv7dwr0	45	20	[	[	-LRB-
cord-010570-ytv7dwr0	45	21	40	40	CD
cord-010570-ytv7dwr0	45	22	]	]	-RRB-
cord-010570-ytv7dwr0	45	23	.	.	.
cord-010570-ytv7dwr0	46	1	The	the	DT
cord-010570-ytv7dwr0	46	2	efficacy	efficacy	NN
cord-010570-ytv7dwr0	46	3	of	of	IN
cord-010570-ytv7dwr0	46	4	serum	serum	NN
cord-010570-ytv7dwr0	46	5	therapy	therapy	NN
cord-010570-ytv7dwr0	46	6	for	for	IN
cord-010570-ytv7dwr0	46	7	whooping	whooping	JJ
cord-010570-ytv7dwr0	46	8	cough	cough	NN
cord-010570-ytv7dwr0	46	9	,	,	,
cord-010570-ytv7dwr0	46	10	anthrax	anthrax	NN
cord-010570-ytv7dwr0	46	11	,	,	,
cord-010570-ytv7dwr0	46	12	dysentery	dysentery	NN
cord-010570-ytv7dwr0	46	13	(	(	-LRB-
cord-010570-ytv7dwr0	46	14	Shigella	Shigella	NNP
cord-010570-ytv7dwr0	46	15	dysenteriae	dysenteriae	NNP
cord-010570-ytv7dwr0	46	16	)	)	-RRB-
cord-010570-ytv7dwr0	46	17	,	,	,
cord-010570-ytv7dwr0	46	18	and	and	CC
cord-010570-ytv7dwr0	46	19	gas	gas	NN
cord-010570-ytv7dwr0	46	20	gangrene	gangrene	NN
cord-010570-ytv7dwr0	46	21	was	be	VBD
cord-010570-ytv7dwr0	46	22	uncertain	uncertain	JJ
cord-010570-ytv7dwr0	46	23	.	.	.
cord-010570-ytv7dwr0	47	1	Human	human	JJ
cord-010570-ytv7dwr0	47	2	convalescent	convalescent	JJ
cord-010570-ytv7dwr0	47	3	serum	serum	NN
cord-010570-ytv7dwr0	47	4	was	be	VBD
cord-010570-ytv7dwr0	47	5	effective	effective	JJ
cord-010570-ytv7dwr0	47	6	for	for	IN
cord-010570-ytv7dwr0	47	7	prophylaxis	prophylaxis	NN
cord-010570-ytv7dwr0	47	8	ofmeasles	ofmeasle	NNS
cord-010570-ytv7dwr0	47	9	,	,	,
cord-010570-ytv7dwr0	47	10	which	which	WDT
cord-010570-ytv7dwr0	47	11	had	have	VBD
cord-010570-ytv7dwr0	47	12	a	a	DT
cord-010570-ytv7dwr0	47	13	mortality	mortality	NN
cord-010570-ytv7dwr0	47	14	rate	rate	NN
cord-010570-ytv7dwr0	47	15	of	of	IN
cord-010570-ytv7dwr0	47	16	6%-7	6%-7	CD
cord-010570-ytv7dwr0	47	17	%	%	NN
cord-010570-ytv7dwr0	47	18	in	in	IN
cord-010570-ytv7dwr0	47	19	some	some	DT
cord-010570-ytv7dwr0	47	20	populations	population	NNS
cord-010570-ytv7dwr0	47	21	[	[	-LRB-
cord-010570-ytv7dwr0	47	22	29	29	CD
cord-010570-ytv7dwr0	47	23	]	]	-RRB-
cord-010570-ytv7dwr0	47	24	[	[	-LRB-
cord-010570-ytv7dwr0	47	25	30	30	CD
cord-010570-ytv7dwr0	47	26	]	]	-RRB-
cord-010570-ytv7dwr0	47	27	[	[	-LRB-
cord-010570-ytv7dwr0	47	28	31	31	CD
cord-010570-ytv7dwr0	47	29	]	]	-RRB-
cord-010570-ytv7dwr0	47	30	.	.	.
cord-010570-ytv7dwr0	48	1	The	the	DT
cord-010570-ytv7dwr0	48	2	effectiveness	effectiveness	NN
cord-010570-ytv7dwr0	48	3	of	of	IN
cord-010570-ytv7dwr0	48	4	serum	serum	NN
cord-010570-ytv7dwr0	48	5	in	in	IN
cord-010570-ytv7dwr0	48	6	the	the	DT
cord-010570-ytv7dwr0	48	7	pre	pre	JJ
cord-010570-ytv7dwr0	48	8	-	-	JJ
cord-010570-ytv7dwr0	48	9	paralytic	paralytic	JJ
cord-010570-ytv7dwr0	48	10	stage	stage	NN
cord-010570-ytv7dwr0	48	11	of	of	IN
cord-010570-ytv7dwr0	48	12	poliomyelitis	poliomyelitis	NN
cord-010570-ytv7dwr0	48	13	was	be	VBD
cord-010570-ytv7dwr0	48	14	uncertain	uncertain	JJ
cord-010570-ytv7dwr0	48	15	[	[	-LRB-
cord-010570-ytv7dwr0	48	16	31	31	CD
cord-010570-ytv7dwr0	48	17	,	,	,
cord-010570-ytv7dwr0	48	18	32	32	CD
cord-010570-ytv7dwr0	48	19	]	]	-RRB-
cord-010570-ytv7dwr0	48	20	.	.	.
cord-010570-ytv7dwr0	49	1	No	no	DT
cord-010570-ytv7dwr0	49	2	consistently	consistently	RB
cord-010570-ytv7dwr0	49	3	effective	effective	JJ
cord-010570-ytv7dwr0	49	4	sera	sera	NNP
cord-010570-ytv7dwr0	49	5	were	be	VBD
cord-010570-ytv7dwr0	49	6	developed	develop	VBN
cord-010570-ytv7dwr0	49	7	against	against	IN
cord-010570-ytv7dwr0	49	8	many	many	JJ
cord-010570-ytv7dwr0	49	9	pathogens	pathogen	NNS
cord-010570-ytv7dwr0	49	10	,	,	,
cord-010570-ytv7dwr0	49	11	including	include	VBG
cord-010570-ytv7dwr0	49	12	Staphylococcus	Staphylococcus	NNP
cord-010570-ytv7dwr0	49	13	[	[	-LRB-
cord-010570-ytv7dwr0	49	14	41	41	CD
cord-010570-ytv7dwr0	49	15	]	]	-RRB-
cord-010570-ytv7dwr0	49	16	,	,	,
cord-010570-ytv7dwr0	49	17	Mycobacterium	Mycobacterium	NNP
cord-010570-ytv7dwr0	49	18	,	,	,
cord-010570-ytv7dwr0	49	19	and	and	CC
cord-010570-ytv7dwr0	49	20	Salmonella	Salmonella	NNP
cord-010570-ytv7dwr0	49	21	species	specie	NNS
cord-010570-ytv7dwr0	49	22	[	[	-LRB-
cord-010570-ytv7dwr0	49	23	42	42	CD
cord-010570-ytv7dwr0	49	24	]	]	-RRB-
cord-010570-ytv7dwr0	49	25	.	.	.
cord-010570-ytv7dwr0	50	1	The	the	DT
cord-010570-ytv7dwr0	50	2	historical	historical	JJ
cord-010570-ytv7dwr0	50	3	use	use	NN
cord-010570-ytv7dwr0	50	4	of	of	IN
cord-010570-ytv7dwr0	50	5	serum	serum	NN
cord-010570-ytv7dwr0	50	6	therapy	therapy	NN
cord-010570-ytv7dwr0	50	7	provides	provide	VBZ
cord-010570-ytv7dwr0	50	8	lessons	lesson	NNS
cord-010570-ytv7dwr0	50	9	for	for	IN
cord-010570-ytv7dwr0	50	10	the	the	DT
cord-010570-ytv7dwr0	50	11	effective	effective	JJ
cord-010570-ytv7dwr0	50	12	use	use	NN
cord-010570-ytv7dwr0	50	13	and	and	CC
cord-010570-ytv7dwr0	50	14	development	development	NN
cord-010570-ytv7dwr0	50	15	of	of	IN
cord-010570-ytv7dwr0	50	16	antibody	antibody	NN
cord-010570-ytv7dwr0	50	17	-	-	HYPH
cord-010570-ytv7dwr0	50	18	based	base	VBN
cord-010570-ytv7dwr0	50	19	therapies	therapy	NNS
cord-010570-ytv7dwr0	50	20	.	.	.
cord-010570-ytv7dwr0	51	1	Accurate	accurate	JJ
cord-010570-ytv7dwr0	51	2	microbiological	microbiological	JJ
cord-010570-ytv7dwr0	51	3	diagnosis	diagnosis	NN
cord-010570-ytv7dwr0	51	4	was	be	VBD
cord-010570-ytv7dwr0	51	5	essential	essential	JJ
cord-010570-ytv7dwr0	51	6	for	for	IN
cord-010570-ytv7dwr0	51	7	successful	successful	JJ
cord-010570-ytv7dwr0	51	8	treatment	treatment	NN
cord-010570-ytv7dwr0	51	9	,	,	,
cord-010570-ytv7dwr0	51	10	and	and	CC
cord-010570-ytv7dwr0	51	11	serum	serum	NN
cord-010570-ytv7dwr0	51	12	therapy	therapy	NN
cord-010570-ytv7dwr0	51	13	was	be	VBD
cord-010570-ytv7dwr0	51	14	most	most	RBS
cord-010570-ytv7dwr0	51	15	effective	effective	JJ
cord-010570-ytv7dwr0	51	16	when	when	WRB
cord-010570-ytv7dwr0	51	17	used	use	VBN
cord-010570-ytv7dwr0	51	18	for	for	IN
cord-010570-ytv7dwr0	51	19	prophylaxis	prophylaxis	NN
cord-010570-ytv7dwr0	51	20	or	or	CC
cord-010570-ytv7dwr0	51	21	for	for	IN
cord-010570-ytv7dwr0	51	22	therapy	therapy	NN
cord-010570-ytv7dwr0	51	23	early	early	RB
cord-010570-ytv7dwr0	51	24	in	in	IN
cord-010570-ytv7dwr0	51	25	the	the	DT
cord-010570-ytv7dwr0	51	26	course	course	NN
cord-010570-ytv7dwr0	51	27	of	of	IN
cord-010570-ytv7dwr0	51	28	infection	infection	NN
cord-010570-ytv7dwr0	51	29	.	.	.
cord-010570-ytv7dwr0	52	1	NOTE	note	NN
cord-010570-ytv7dwr0	52	2	.	.	.
cord-010570-ytv7dwr0	53	1	This	this	DT
cord-010570-ytv7dwr0	53	2	is	be	VBZ
cord-010570-ytv7dwr0	53	3	not	not	RB
cord-010570-ytv7dwr0	53	4	a	a	DT
cord-010570-ytv7dwr0	53	5	complete	complete	JJ
cord-010570-ytv7dwr0	53	6	list	list	NN
cord-010570-ytv7dwr0	53	7	.	.	.
cord-010570-ytv7dwr0	54	1	[	[	-LRB-
cord-010570-ytv7dwr0	54	2	7	7	CD
cord-010570-ytv7dwr0	54	3	]	]	-RRB-
cord-010570-ytv7dwr0	54	4	[	[	-LRB-
cord-010570-ytv7dwr0	54	5	7	7	CD
cord-010570-ytv7dwr0	54	6	]	]	-RRB-
cord-010570-ytv7dwr0	54	7	[	[	-LRB-
cord-010570-ytv7dwr0	54	8	8	8	CD
cord-010570-ytv7dwr0	54	9	]	]	-RRB-
cord-010570-ytv7dwr0	54	10	[	[	-LRB-
cord-010570-ytv7dwr0	54	11	9	9	CD
cord-010570-ytv7dwr0	54	12	]	]	-RRB-
cord-010570-ytv7dwr0	55	1	[	[	-LRB-
cord-010570-ytv7dwr0	55	2	10	10	CD
cord-010570-ytv7dwr0	55	3	]	]	-RRB-
cord-010570-ytv7dwr0	56	1	Nevertheless	nevertheless	RB
cord-010570-ytv7dwr0	56	2	,	,	,
cord-010570-ytv7dwr0	56	3	it	-PRON-	PRP
cord-010570-ytv7dwr0	56	4	was	be	VBD
cord-010570-ytv7dwr0	56	5	possible	possible	JJ
cord-010570-ytv7dwr0	56	6	to	to	TO
cord-010570-ytv7dwr0	56	7	treat	treat	VB
cord-010570-ytv7dwr0	56	8	established	established	JJ
cord-010570-ytv7dwr0	56	9	bacterial	bacterial	JJ
cord-010570-ytv7dwr0	56	10	infections	infection	NNS
cord-010570-ytv7dwr0	56	11	such	such	JJ
cord-010570-ytv7dwr0	56	12	as	as	IN
cord-010570-ytv7dwr0	56	13	meningococcal	meningococcal	JJ
cord-010570-ytv7dwr0	56	14	meningitis	meningitis	NN
cord-010570-ytv7dwr0	56	15	and	and	CC
cord-010570-ytv7dwr0	56	16	pneumococcal	pneumococcal	JJ
cord-010570-ytv7dwr0	56	17	pneumonia	pneumonia	NN
cord-010570-ytv7dwr0	56	18	if	if	IN
cord-010570-ytv7dwr0	56	19	antibody	antibody	NN
cord-010570-ytv7dwr0	56	20	was	be	VBD
cord-010570-ytv7dwr0	56	21	administered	administer	VBN
cord-010570-ytv7dwr0	56	22	shortly	shortly	RB
cord-010570-ytv7dwr0	56	23	after	after	IN
cord-010570-ytv7dwr0	56	24	symptoms	symptom	NNS
cord-010570-ytv7dwr0	56	25	began	begin	VBD
cord-010570-ytv7dwr0	56	26	[	[	-LRB-
cord-010570-ytv7dwr0	56	27	7	7	CD
cord-010570-ytv7dwr0	56	28	]	]	-RRB-
cord-010570-ytv7dwr0	56	29	.	.	.
cord-010570-ytv7dwr0	57	1	Antibodies	antibody	NNS
cord-010570-ytv7dwr0	57	2	functioned	function	VBD
cord-010570-ytv7dwr0	57	3	as	as	IN
cord-010570-ytv7dwr0	57	4	direct	direct	JJ
cord-010570-ytv7dwr0	57	5	antibacterial	antibacterial	JJ
cord-010570-ytv7dwr0	57	6	agents	agent	NNS
cord-010570-ytv7dwr0	57	7	(	(	-LRB-
cord-010570-ytv7dwr0	57	8	e.g.	e.g.	RB
cord-010570-ytv7dwr0	57	9	,	,	,
cord-010570-ytv7dwr0	57	10	pneumococcal	pneumococcal	JJ
cord-010570-ytv7dwr0	57	11	antisera	antisera	NN
cord-010570-ytv7dwr0	57	12	)	)	-RRB-
cord-010570-ytv7dwr0	57	13	or	or	CC
cord-010570-ytv7dwr0	57	14	antitoxins	antitoxin	NNS
cord-010570-ytv7dwr0	57	15	(	(	-LRB-
cord-010570-ytv7dwr0	57	16	e.g.	e.g.	RB
cord-010570-ytv7dwr0	57	17	,	,	,
cord-010570-ytv7dwr0	57	18	diphtherial	diphtherial	JJ
cord-010570-ytv7dwr0	57	19	antisera	antisera	NNP
cord-010570-ytv7dwr0	57	20	)	)	-RRB-
cord-010570-ytv7dwr0	57	21	.	.	.
cord-010570-ytv7dwr0	58	1	Nonphysiological	nonphysiological	JJ
cord-010570-ytv7dwr0	58	2	and	and	CC
cord-010570-ytv7dwr0	58	3	nontherapeutic	nontherapeutic	JJ
cord-010570-ytv7dwr0	58	4	animal	animal	NN
cord-010570-ytv7dwr0	58	5	models	model	NNS
cord-010570-ytv7dwr0	58	6	of	of	IN
cord-010570-ytv7dwr0	58	7	infection	infection	NN
cord-010570-ytv7dwr0	58	8	allowed	allow	VBD
cord-010570-ytv7dwr0	58	9	investigators	investigator	NNS
cord-010570-ytv7dwr0	58	10	to	to	TO
cord-010570-ytv7dwr0	58	11	successfully	successfully	RB
cord-010570-ytv7dwr0	58	12	identify	identify	VB
cord-010570-ytv7dwr0	58	13	clinically	clinically	RB
cord-010570-ytv7dwr0	58	14	useful	useful	JJ
cord-010570-ytv7dwr0	58	15	antibody	antibody	NN
cord-010570-ytv7dwr0	58	16	reagents	reagent	NNS
cord-010570-ytv7dwr0	58	17	[	[	-LRB-
cord-010570-ytv7dwr0	58	18	7	7	CD
cord-010570-ytv7dwr0	58	19	]	]	-RRB-
cord-010570-ytv7dwr0	58	20	.	.	.
cord-010570-ytv7dwr0	59	1	A	a	DT
cord-010570-ytv7dwr0	59	2	considerable	considerable	JJ
cord-010570-ytv7dwr0	59	3	amount	amount	NN
cord-010570-ytv7dwr0	59	4	of	of	IN
cord-010570-ytv7dwr0	59	5	basic	basic	JJ
cord-010570-ytv7dwr0	59	6	immunologic	immunologic	JJ
cord-010570-ytv7dwr0	59	7	and	and	CC
cord-010570-ytv7dwr0	59	8	microbiological	microbiological	JJ
cord-010570-ytv7dwr0	59	9	research	research	NN
cord-010570-ytv7dwr0	59	10	was	be	VBD
cord-010570-ytv7dwr0	59	11	required	require	VBN
cord-010570-ytv7dwr0	59	12	to	to	TO
cord-010570-ytv7dwr0	59	13	develop	develop	VB
cord-010570-ytv7dwr0	59	14	each	each	DT
cord-010570-ytv7dwr0	59	15	serum	serum	NN
cord-010570-ytv7dwr0	59	16	,	,	,
cord-010570-ytv7dwr0	59	17	and	and	CC
cord-010570-ytv7dwr0	59	18	many	many	JJ
cord-010570-ytv7dwr0	59	19	fundamental	fundamental	JJ
cord-010570-ytv7dwr0	59	20	discoveries	discovery	NNS
cord-010570-ytv7dwr0	59	21	were	be	VBD
cord-010570-ytv7dwr0	59	22	made	make	VBN
cord-010570-ytv7dwr0	59	23	in	in	IN
cord-010570-ytv7dwr0	59	24	the	the	DT
cord-010570-ytv7dwr0	59	25	search	search	NN
cord-010570-ytv7dwr0	59	26	for	for	IN
cord-010570-ytv7dwr0	59	27	better	well	JJR
cord-010570-ytv7dwr0	59	28	sera	sera	NNP
cord-010570-ytv7dwr0	59	29	.	.	.
cord-010570-ytv7dwr0	60	1	(	(	-LRB-
cord-010570-ytv7dwr0	60	2	The	the	DT
cord-010570-ytv7dwr0	60	3	contributions	contribution	NNS
cord-010570-ytv7dwr0	60	4	of	of	IN
cord-010570-ytv7dwr0	60	5	pneumococcal	pneumococcal	JJ
cord-010570-ytv7dwr0	60	6	research	research	NN
cord-010570-ytv7dwr0	60	7	to	to	IN
cord-010570-ytv7dwr0	60	8	basic	basic	JJ
cord-010570-ytv7dwr0	60	9	science	science	NN
cord-010570-ytv7dwr0	60	10	are	be	VBP
cord-010570-ytv7dwr0	60	11	discussed	discuss	VBN
cord-010570-ytv7dwr0	60	12	in	in	IN
cord-010570-ytv7dwr0	60	13	[	[	-LRB-
cord-010570-ytv7dwr0	60	14	43	43	CD
cord-010570-ytv7dwr0	60	15	]	]	-RRB-
cord-010570-ytv7dwr0	60	16	.	.	.
cord-010570-ytv7dwr0	60	17	)	)	-RRB-
cord-010570-ytv7dwr0	61	1	Sulfonamides	sulfonamide	NNS
cord-010570-ytv7dwr0	61	2	were	be	VBD
cord-010570-ytv7dwr0	61	3	introduced	introduce	VBN
cord-010570-ytv7dwr0	61	4	in	in	IN
cord-010570-ytv7dwr0	61	5	1935	1935	CD
cord-010570-ytv7dwr0	61	6	and	and	CC
cord-010570-ytv7dwr0	61	7	rapidly	rapidly	RB
cord-010570-ytv7dwr0	61	8	became	become	VBD
cord-010570-ytv7dwr0	61	9	the	the	DT
cord-010570-ytv7dwr0	61	10	standard	standard	JJ
cord-010570-ytv7dwr0	61	11	therapy	therapy	NN
cord-010570-ytv7dwr0	61	12	for	for	IN
cord-010570-ytv7dwr0	61	13	many	many	JJ
cord-010570-ytv7dwr0	61	14	infections	infection	NNS
cord-010570-ytv7dwr0	61	15	[	[	-LRB-
cord-010570-ytv7dwr0	61	16	44	44	CD
cord-010570-ytv7dwr0	61	17	]	]	-RRB-
cord-010570-ytv7dwr0	61	18	.	.	.
cord-010570-ytv7dwr0	62	1	Because	because	IN
cord-010570-ytv7dwr0	62	2	antimicrobial	antimicrobial	JJ
cord-010570-ytv7dwr0	62	3	chemotherapy	chemotherapy	NN
cord-010570-ytv7dwr0	62	4	had	have	VBD
cord-010570-ytv7dwr0	62	5	significant	significant	JJ
cord-010570-ytv7dwr0	62	6	advantages	advantage	NNS
cord-010570-ytv7dwr0	62	7	over	over	IN
cord-010570-ytv7dwr0	62	8	serum	serum	NN
cord-010570-ytv7dwr0	62	9	therapy	therapy	NN
cord-010570-ytv7dwr0	62	10	,	,	,
cord-010570-ytv7dwr0	62	11	the	the	DT
cord-010570-ytv7dwr0	62	12	latter	latter	JJ
cord-010570-ytv7dwr0	62	13	was	be	VBD
cord-010570-ytv7dwr0	62	14	largely	largely	RB
cord-010570-ytv7dwr0	62	15	abandoned	abandon	VBN
cord-010570-ytv7dwr0	62	16	.	.	.
cord-010570-ytv7dwr0	63	1	Systemic	systemic	JJ
cord-010570-ytv7dwr0	63	2	administration	administration	NN
cord-010570-ytv7dwr0	63	3	of	of	IN
cord-010570-ytv7dwr0	63	4	animal	animal	NNP
cord-010570-ytv7dwr0	63	5	sera	sera	NNP
cord-010570-ytv7dwr0	63	6	caused	cause	VBD
cord-010570-ytv7dwr0	63	7	fevers	fever	NNS
cord-010570-ytv7dwr0	63	8	,	,	,
cord-010570-ytv7dwr0	63	9	chills	chill	NNS
cord-010570-ytv7dwr0	63	10	,	,	,
cord-010570-ytv7dwr0	63	11	and	and	CC
cord-010570-ytv7dwr0	63	12	allergic	allergic	JJ
cord-010570-ytv7dwr0	63	13	reactions	reaction	NNS
cord-010570-ytv7dwr0	63	14	[	[	-LRB-
cord-010570-ytv7dwr0	63	15	23	23	CD
cord-010570-ytv7dwr0	63	16	,	,	,
cord-010570-ytv7dwr0	63	17	45	45	CD
cord-010570-ytv7dwr0	63	18	]	]	-RRB-
cord-010570-ytv7dwr0	63	19	;	;	:
cord-010570-ytv7dwr0	63	20	"	"	``
cord-010570-ytv7dwr0	63	21	serum	serum	NN
cord-010570-ytv7dwr0	63	22	sickness	sickness	NN
cord-010570-ytv7dwr0	63	23	,	,	,
cord-010570-ytv7dwr0	63	24	"	"	''
cord-010570-ytv7dwr0	63	25	a	a	DT
cord-010570-ytv7dwr0	63	26	self	self	NN
cord-010570-ytv7dwr0	63	27	-	-	HYPH
cord-010570-ytv7dwr0	63	28	limited	limit	VBN
cord-010570-ytv7dwr0	63	29	syndrome	syndrome	NN
cord-010570-ytv7dwr0	63	30	characterized	characterize	VBN
cord-010570-ytv7dwr0	63	31	by	by	IN
cord-010570-ytv7dwr0	63	32	rash	rash	NN
cord-010570-ytv7dwr0	63	33	,	,	,
cord-010570-ytv7dwr0	63	34	proteinuria	proteinuria	NN
cord-010570-ytv7dwr0	63	35	,	,	,
cord-010570-ytv7dwr0	63	36	and	and	CC
cord-010570-ytv7dwr0	63	37	arthralgias	arthralgias	NNP
cord-010570-ytv7dwr0	63	38	,	,	,
cord-010570-ytv7dwr0	63	39	occurred	occur	VBD
cord-010570-ytv7dwr0	63	40	in	in	IN
cord-010570-ytv7dwr0	63	41	10%-50	10%-50	CD
cord-010570-ytv7dwr0	63	42	%	%	NN
cord-010570-ytv7dwr0	63	43	of	of	IN
cord-010570-ytv7dwr0	63	44	patients	patient	NNS
cord-010570-ytv7dwr0	63	45	because	because	IN
cord-010570-ytv7dwr0	63	46	of	of	IN
cord-010570-ytv7dwr0	63	47	immune	immune	JJ
cord-010570-ytv7dwr0	63	48	complex	complex	JJ
cord-010570-ytv7dwr0	63	49	disease	disease	NN
cord-010570-ytv7dwr0	63	50	.	.	.
cord-010570-ytv7dwr0	64	1	In	in	IN
cord-010570-ytv7dwr0	64	2	addition	addition	NN
cord-010570-ytv7dwr0	64	3	,	,	,
cord-010570-ytv7dwr0	64	4	strain	strain	NN
cord-010570-ytv7dwr0	64	5	typing	typing	NN
cord-010570-ytv7dwr0	64	6	was	be	VBD
cord-010570-ytv7dwr0	64	7	necessary	necessary	JJ
cord-010570-ytv7dwr0	64	8	for	for	IN
cord-010570-ytv7dwr0	64	9	choosing	choose	VBG
cord-010570-ytv7dwr0	64	10	pneumococcal	pneumococcal	JJ
cord-010570-ytv7dwr0	64	11	antisera	antisera	NN
cord-010570-ytv7dwr0	64	12	;	;	:
cord-010570-ytv7dwr0	64	13	there	there	EX
cord-010570-ytv7dwr0	64	14	was	be	VBD
cord-010570-ytv7dwr0	64	15	significant	significant	JJ
cord-010570-ytv7dwr0	64	16	lot	lot	NN
cord-010570-ytv7dwr0	64	17	-	-	HYPH
cord-010570-ytv7dwr0	64	18	to	to	IN
cord-010570-ytv7dwr0	64	19	-	-	HYPH
cord-010570-ytv7dwr0	64	20	lot	lot	NN
cord-010570-ytv7dwr0	64	21	variation	variation	NN
cord-010570-ytv7dwr0	64	22	in	in	IN
cord-010570-ytv7dwr0	64	23	serum	serum	NN
cord-010570-ytv7dwr0	64	24	efficacy	efficacy	NN
cord-010570-ytv7dwr0	64	25	[	[	-LRB-
cord-010570-ytv7dwr0	64	26	46	46	CD
cord-010570-ytv7dwr0	64	27	]	]	-RRB-
cord-010570-ytv7dwr0	64	28	;	;	:
cord-010570-ytv7dwr0	64	29	and	and	CC
cord-010570-ytv7dwr0	64	30	dosing	dosing	NN
cord-010570-ytv7dwr0	64	31	was	be	VBD
cord-010570-ytv7dwr0	64	32	based	base	VBN
cord-010570-ytv7dwr0	64	33	on	on	IN
cord-010570-ytv7dwr0	64	34	clinical	clinical	JJ
cord-010570-ytv7dwr0	64	35	experience	experience	NN
cord-010570-ytv7dwr0	64	36	.	.	.
cord-010570-ytv7dwr0	65	1	Inadequate	inadequate	JJ
cord-010570-ytv7dwr0	65	2	dosage	dosage	NN
cord-010570-ytv7dwr0	65	3	,	,	,
cord-010570-ytv7dwr0	65	4	delays	delay	NNS
cord-010570-ytv7dwr0	65	5	in	in	IN
cord-010570-ytv7dwr0	65	6	treatment	treatment	NN
cord-010570-ytv7dwr0	65	7	,	,	,
cord-010570-ytv7dwr0	65	8	errors	error	NNS
cord-010570-ytv7dwr0	65	9	in	in	IN
cord-010570-ytv7dwr0	65	10	typing	typing	NN
cord-010570-ytv7dwr0	65	11	,	,	,
cord-010570-ytv7dwr0	65	12	mixed	mixed	JJ
cord-010570-ytv7dwr0	65	13	infections	infection	NNS
cord-010570-ytv7dwr0	65	14	,	,	,
cord-010570-ytv7dwr0	65	15	and	and	CC
cord-010570-ytv7dwr0	65	16	complicated	complicated	JJ
cord-010570-ytv7dwr0	65	17	infections	infection	NNS
cord-010570-ytv7dwr0	65	18	(	(	-LRB-
cord-010570-ytv7dwr0	65	19	e.g.	e.g.	RB
cord-010570-ytv7dwr0	65	20	,	,	,
cord-010570-ytv7dwr0	65	21	empyema	empyema	NNP
cord-010570-ytv7dwr0	65	22	)	)	-RRB-
cord-010570-ytv7dwr0	65	23	could	could	MD
cord-010570-ytv7dwr0	65	24	result	result	VB
cord-010570-ytv7dwr0	65	25	in	in	IN
cord-010570-ytv7dwr0	65	26	failure	failure	NN
cord-010570-ytv7dwr0	65	27	of	of	IN
cord-010570-ytv7dwr0	65	28	serum	serum	NN
cord-010570-ytv7dwr0	65	29	therapy	therapy	NN
cord-010570-ytv7dwr0	65	30	[	[	-LRB-
cord-010570-ytv7dwr0	65	31	47	47	CD
cord-010570-ytv7dwr0	65	32	]	]	-RRB-
cord-010570-ytv7dwr0	65	33	.	.	.
cord-010570-ytv7dwr0	66	1	Serum	serum	NN
cord-010570-ytv7dwr0	66	2	was	be	VBD
cord-010570-ytv7dwr0	66	3	expensive	expensive	JJ
cord-010570-ytv7dwr0	66	4	because	because	IN
cord-010570-ytv7dwr0	66	5	of	of	IN
cord-010570-ytv7dwr0	66	6	the	the	DT
cord-010570-ytv7dwr0	66	7	costs	cost	NNS
cord-010570-ytv7dwr0	66	8	of	of	IN
cord-010570-ytv7dwr0	66	9	animal	animal	NN
cord-010570-ytv7dwr0	66	10	husbandry	husbandry	NN
cord-010570-ytv7dwr0	66	11	,	,	,
cord-010570-ytv7dwr0	66	12	antibody	antibody	NN
cord-010570-ytv7dwr0	66	13	purification	purification	NN
cord-010570-ytv7dwr0	66	14	,	,	,
cord-010570-ytv7dwr0	66	15	refrigeration	refrigeration	NN
cord-010570-ytv7dwr0	66	16	,	,	,
cord-010570-ytv7dwr0	66	17	and	and	CC
cord-010570-ytv7dwr0	66	18	reliance	reliance	NN
cord-010570-ytv7dwr0	66	19	on	on	IN
cord-010570-ytv7dwr0	66	20	mouse	mouse	NN
cord-010570-ytv7dwr0	66	21	protection	protection	NN
cord-010570-ytv7dwr0	66	22	tests	test	NNS
cord-010570-ytv7dwr0	66	23	for	for	IN
cord-010570-ytv7dwr0	66	24	standardization	standardization	NN
cord-010570-ytv7dwr0	66	25	.	.	.
cord-010570-ytv7dwr0	67	1	Chemotherapy	chemotherapy	NN
cord-010570-ytv7dwr0	67	2	was	be	VBD
cord-010570-ytv7dwr0	67	3	less	less	RBR
cord-010570-ytv7dwr0	67	4	toxic	toxic	JJ
cord-010570-ytv7dwr0	67	5	and	and	CC
cord-010570-ytv7dwr0	67	6	more	more	RBR
cord-010570-ytv7dwr0	67	7	effective	effective	JJ
cord-010570-ytv7dwr0	67	8	than	than	IN
cord-010570-ytv7dwr0	67	9	serum	serum	NN
cord-010570-ytv7dwr0	67	10	therapy	therapy	NN
cord-010570-ytv7dwr0	67	11	.	.	.
cord-010570-ytv7dwr0	68	1	Treatment	treatment	NN
cord-010570-ytv7dwr0	68	2	with	with	IN
cord-010570-ytv7dwr0	68	3	type	type	NN
cord-010570-ytv7dwr0	68	4	-	-	HYPH
cord-010570-ytv7dwr0	68	5	specific	specific	JJ
cord-010570-ytv7dwr0	68	6	serum	serum	NN
cord-010570-ytv7dwr0	68	7	reduced	reduce	VBD
cord-010570-ytv7dwr0	68	8	the	the	DT
cord-010570-ytv7dwr0	68	9	mortality	mortality	NN
cord-010570-ytv7dwr0	68	10	of	of	IN
cord-010570-ytv7dwr0	68	11	pneumococcal	pneumococcal	JJ
cord-010570-ytv7dwr0	68	12	pneumonia	pneumonia	NN
cord-010570-ytv7dwr0	68	13	from	from	IN
cord-010570-ytv7dwr0	68	14	30%-40	30%-40	CD
cord-010570-ytv7dwr0	68	15	%	%	NN
cord-010570-ytv7dwr0	68	16	to	to	IN
cord-010570-ytv7dwr0	68	17	10%-20	10%-20	CD
cord-010570-ytv7dwr0	68	18	%	%	NN
cord-010570-ytv7dwr0	68	19	[	[	-LRB-
cord-010570-ytv7dwr0	68	20	7	7	CD
cord-010570-ytv7dwr0	68	21	]	]	-RRB-
cord-010570-ytv7dwr0	68	22	,	,	,
cord-010570-ytv7dwr0	68	23	whereas	whereas	IN
cord-010570-ytv7dwr0	68	24	the	the	DT
cord-010570-ytv7dwr0	68	25	mortality	mortality	NN
cord-010570-ytv7dwr0	68	26	rate	rate	NN
cord-010570-ytv7dwr0	68	27	among	among	IN
cord-010570-ytv7dwr0	68	28	patients	patient	NNS
cord-010570-ytv7dwr0	68	29	treated	treat	VBN
cord-010570-ytv7dwr0	68	30	with	with	IN
cord-010570-ytv7dwr0	68	31	sulfonamide	sulfonamide	NN
cord-010570-ytv7dwr0	68	32	was	be	VBD
cord-010570-ytv7dwr0	68	33	7	7	CD
cord-010570-ytv7dwr0	68	34	%	%	NN
cord-010570-ytv7dwr0	68	35	[	[	-LRB-
cord-010570-ytv7dwr0	68	36	48	48	CD
cord-010570-ytv7dwr0	68	37	]	]	-RRB-
cord-010570-ytv7dwr0	68	38	.	.	.
cord-010570-ytv7dwr0	69	1	Serum	serum	NN
cord-010570-ytv7dwr0	69	2	therapy	therapy	NN
cord-010570-ytv7dwr0	69	3	reduced	reduce	VBD
cord-010570-ytv7dwr0	69	4	the	the	DT
cord-010570-ytv7dwr0	69	5	mortality	mortality	NN
cord-010570-ytv7dwr0	69	6	rate	rate	NN
cord-010570-ytv7dwr0	69	7	of	of	IN
cord-010570-ytv7dwr0	69	8	erysipelas	erysipela	NNS
cord-010570-ytv7dwr0	69	9	from	from	IN
cord-010570-ytv7dwr0	69	10	10	10	CD
cord-010570-ytv7dwr0	69	11	%	%	NN
cord-010570-ytv7dwr0	69	12	to	to	TO
cord-010570-ytv7dwr0	69	13	7	7	CD
cord-010570-ytv7dwr0	69	14	%	%	NN
cord-010570-ytv7dwr0	69	15	[	[	-LRB-
cord-010570-ytv7dwr0	69	16	37	37	CD
cord-010570-ytv7dwr0	69	17	]	]	-RRB-
cord-010570-ytv7dwr0	69	18	,	,	,
cord-010570-ytv7dwr0	69	19	whereas	whereas	IN
cord-010570-ytv7dwr0	69	20	the	the	DT
cord-010570-ytv7dwr0	69	21	mortality	mortality	NN
cord-010570-ytv7dwr0	69	22	rate	rate	NN
cord-010570-ytv7dwr0	69	23	for	for	IN
cord-010570-ytv7dwr0	69	24	patients	patient	NNS
cord-010570-ytv7dwr0	69	25	treated	treat	VBN
cord-010570-ytv7dwr0	69	26	with	with	IN
cord-010570-ytv7dwr0	69	27	sulfonamides	sulfonamide	NNS
cord-010570-ytv7dwr0	69	28	was	be	VBD
cord-010570-ytv7dwr0	69	29	1%-2	1%-2	CD
cord-010570-ytv7dwr0	69	30	%	%	NN
cord-010570-ytv7dwr0	69	31	[	[	-LRB-
cord-010570-ytv7dwr0	69	32	49	49	CD
cord-010570-ytv7dwr0	69	33	]	]	-RRB-
cord-010570-ytv7dwr0	69	34	.	.	.
cord-010570-ytv7dwr0	70	1	For	for	IN
cord-010570-ytv7dwr0	70	2	meningococcal	meningococcal	JJ
cord-010570-ytv7dwr0	70	3	meningitis	meningitis	NN
cord-010570-ytv7dwr0	70	4	,	,	,
cord-010570-ytv7dwr0	70	5	the	the	DT
cord-010570-ytv7dwr0	70	6	efficacy	efficacy	NN
cord-010570-ytv7dwr0	70	7	of	of	IN
cord-010570-ytv7dwr0	70	8	serum	serum	NN
cord-010570-ytv7dwr0	70	9	depended	depend	VBD
cord-010570-ytv7dwr0	70	10	on	on	IN
cord-010570-ytv7dwr0	70	11	the	the	DT
cord-010570-ytv7dwr0	70	12	epidemic	epidemic	NN
cord-010570-ytv7dwr0	70	13	.	.	.
cord-010570-ytv7dwr0	71	1	In	in	IN
cord-010570-ytv7dwr0	71	2	the	the	DT
cord-010570-ytv7dwr0	71	3	mid-1930s	mid-1930	NNS
cord-010570-ytv7dwr0	71	4	,	,	,
cord-010570-ytv7dwr0	71	5	Waghelstein	Waghelstein	NNP
cord-010570-ytv7dwr0	71	6	[	[	-LRB-
cord-010570-ytv7dwr0	71	7	50	50	CD
cord-010570-ytv7dwr0	71	8	]	]	-RRB-
cord-010570-ytv7dwr0	71	9	reported	report	VBD
cord-010570-ytv7dwr0	71	10	that	that	IN
cord-010570-ytv7dwr0	71	11	the	the	DT
cord-010570-ytv7dwr0	71	12	mortality	mortality	NN
cord-010570-ytv7dwr0	71	13	rate	rate	NN
cord-010570-ytv7dwr0	71	14	for	for	IN
cord-010570-ytv7dwr0	71	15	patients	patient	NNS
cord-010570-ytv7dwr0	71	16	with	with	IN
cord-010570-ytv7dwr0	71	17	meningococcal	meningococcal	JJ
cord-010570-ytv7dwr0	71	18	meningitis	meningitis	NN
cord-010570-ytv7dwr0	71	19	who	who	WP
cord-010570-ytv7dwr0	71	20	were	be	VBD
cord-010570-ytv7dwr0	71	21	treated	treat	VBN
cord-010570-ytv7dwr0	71	22	at	at	IN
cord-010570-ytv7dwr0	71	23	Sydenham	Sydenham	NNP
cord-010570-ytv7dwr0	71	24	Hospital	Hospital	NNP
cord-010570-ytv7dwr0	71	25	(	(	-LRB-
cord-010570-ytv7dwr0	71	26	Baltimore	Baltimore	NNP
cord-010570-ytv7dwr0	71	27	,	,	,
cord-010570-ytv7dwr0	71	28	MD	MD	NNP
cord-010570-ytv7dwr0	71	29	)	)	-RRB-
cord-010570-ytv7dwr0	71	30	with	with	IN
cord-010570-ytv7dwr0	71	31	sulfonamide	sulfonamide	NN
cord-010570-ytv7dwr0	71	32	was	be	VBD
cord-010570-ytv7dwr0	71	33	15.3	15.3	CD
cord-010570-ytv7dwr0	71	34	%	%	NN
cord-010570-ytv7dwr0	71	35	and	and	CC
cord-010570-ytv7dwr0	71	36	for	for	IN
cord-010570-ytv7dwr0	71	37	those	those	DT
cord-010570-ytv7dwr0	71	38	treated	treat	VBN
cord-010570-ytv7dwr0	71	39	with	with	IN
cord-010570-ytv7dwr0	71	40	serum	serum	NN
cord-010570-ytv7dwr0	71	41	it	-PRON-	PRP
cord-010570-ytv7dwr0	71	42	was	be	VBD
cord-010570-ytv7dwr0	71	43	27	27	CD
cord-010570-ytv7dwr0	71	44	%	%	NN
cord-010570-ytv7dwr0	71	45	.	.	.
cord-010570-ytv7dwr0	72	1	In	in	IN
cord-010570-ytv7dwr0	72	2	controlled	control	VBN
cord-010570-ytv7dwr0	72	3	trials	trial	NNS
cord-010570-ytv7dwr0	72	4	,	,	,
cord-010570-ytv7dwr0	72	5	the	the	DT
cord-010570-ytv7dwr0	72	6	superiority	superiority	NN
cord-010570-ytv7dwr0	72	7	of	of	IN
cord-010570-ytv7dwr0	72	8	chemotherapy	chemotherapy	NN
cord-010570-ytv7dwr0	72	9	over	over	IN
cord-010570-ytv7dwr0	72	10	serum	serum	NN
cord-010570-ytv7dwr0	72	11	therapy	therapy	NN
cord-010570-ytv7dwr0	72	12	was	be	VBD
cord-010570-ytv7dwr0	72	13	lessevident	lessevident	JJ
cord-010570-ytv7dwr0	72	14	.	.	.
cord-010570-ytv7dwr0	73	1	For	for	IN
cord-010570-ytv7dwr0	73	2	example	example	NN
cord-010570-ytv7dwr0	73	3	,	,	,
cord-010570-ytv7dwr0	73	4	the	the	DT
cord-010570-ytv7dwr0	73	5	mortality	mortality	NN
cord-010570-ytv7dwr0	73	6	among	among	IN
cord-010570-ytv7dwr0	73	7	patients	patient	NNS
cord-010570-ytv7dwr0	73	8	with	with	IN
cord-010570-ytv7dwr0	73	9	meningococcal	meningococcal	JJ
cord-010570-ytv7dwr0	73	10	meningitis	meningitis	NN
cord-010570-ytv7dwr0	73	11	who	who	WP
cord-010570-ytv7dwr0	73	12	were	be	VBD
cord-010570-ytv7dwr0	73	13	treated	treat	VBN
cord-010570-ytv7dwr0	73	14	early	early	RB
cord-010570-ytv7dwr0	73	15	with	with	IN
cord-010570-ytv7dwr0	73	16	adequate	adequate	JJ
cord-010570-ytv7dwr0	73	17	serum	serum	NN
cord-010570-ytv7dwr0	73	18	therapy	therapy	NN
cord-010570-ytv7dwr0	73	19	was	be	VBD
cord-010570-ytv7dwr0	73	20	16.7	16.7	CD
cord-010570-ytv7dwr0	73	21	%	%	NN
cord-010570-ytv7dwr0	73	22	vs.	vs.	IN
cord-010570-ytv7dwr0	73	23	11.6	11.6	CD
cord-010570-ytv7dwr0	73	24	%	%	NN
cord-010570-ytv7dwr0	73	25	for	for	IN
cord-010570-ytv7dwr0	73	26	sulfanilamide	sulfanilamide	NN
cord-010570-ytv7dwr0	73	27	therapy	therapy	NN
cord-010570-ytv7dwr0	73	28	[	[	-LRB-
cord-010570-ytv7dwr0	73	29	50	50	CD
cord-010570-ytv7dwr0	73	30	]	]	-RRB-
cord-010570-ytv7dwr0	73	31	.	.	.
cord-010570-ytv7dwr0	74	1	The	the	DT
cord-010570-ytv7dwr0	74	2	mortality	mortality	NN
cord-010570-ytv7dwr0	74	3	among	among	IN
cord-010570-ytv7dwr0	74	4	patients	patient	NNS
cord-010570-ytv7dwr0	74	5	with	with	IN
cord-010570-ytv7dwr0	74	6	pneumococcal	pneumococcal	JJ
cord-010570-ytv7dwr0	74	7	pneumonia	pneumonia	NN
cord-010570-ytv7dwr0	74	8	treated	treat	VBN
cord-010570-ytv7dwr0	74	9	with	with	IN
cord-010570-ytv7dwr0	74	10	antimicrobial	antimicrobial	JJ
cord-010570-ytv7dwr0	74	11	drugs	drug	NNS
cord-010570-ytv7dwr0	74	12	or	or	CC
cord-010570-ytv7dwr0	74	13	serum	serum	NN
cord-010570-ytv7dwr0	74	14	was	be	VBD
cord-010570-ytv7dwr0	74	15	11	11	CD
cord-010570-ytv7dwr0	74	16	%	%	NN
cord-010570-ytv7dwr0	74	17	and	and	CC
cord-010570-ytv7dwr0	74	18	16.7	16.7	CD
cord-010570-ytv7dwr0	74	19	%	%	NN
cord-010570-ytv7dwr0	74	20	,	,	,
cord-010570-ytv7dwr0	74	21	respectively	respectively	RB
cord-010570-ytv7dwr0	74	22	,	,	,
cord-010570-ytv7dwr0	74	23	but	but	CC
cord-010570-ytv7dwr0	74	24	there	there	EX
cord-010570-ytv7dwr0	74	25	was	be	VBD
cord-010570-ytv7dwr0	74	26	no	no	DT
cord-010570-ytv7dwr0	74	27	difference	difference	NN
cord-010570-ytv7dwr0	74	28	in	in	IN
cord-010570-ytv7dwr0	74	29	the	the	DT
cord-010570-ytv7dwr0	74	30	mortality	mortality	NN
cord-010570-ytv7dwr0	74	31	rates	rate	NNS
cord-010570-ytv7dwr0	74	32	among	among	IN
cord-010570-ytv7dwr0	74	33	younger	young	JJR
cord-010570-ytv7dwr0	74	34	..	..	.
cord-010570-ytv7dwr0	75	1	Literature	literature	NN
cord-010570-ytv7dwr0	75	2	sent	send	VBN
cord-010570-ytv7dwr0	75	3	on	on	IN
cord-010570-ytv7dwr0	75	4	request	request	NN
cord-010570-ytv7dwr0	75	5	.	.	.
cord-010570-ytv7dwr0	76	1	is	be	VBZ
cord-010570-ytv7dwr0	76	2	used	use	VBN
cord-010570-ytv7dwr0	76	3	at	at	IN
cord-010570-ytv7dwr0	76	4	Bellevue	Bellevue	NNP
cord-010570-ytv7dwr0	76	5	Hospital	Hospital	NNP
cord-010570-ytv7dwr0	76	6	.	.	.
cord-010570-ytv7dwr0	77	1	It	-PRON-	PRP
cord-010570-ytv7dwr0	77	2	is	be	VBZ
cord-010570-ytv7dwr0	77	3	supplied	supply	VBN
cord-010570-ytv7dwr0	77	4	in	in	IN
cord-010570-ytv7dwr0	77	5	packages	package	NNS
cord-010570-ytv7dwr0	77	6	of	of	IN
cord-010570-ytv7dwr0	77	7	one	one	CD
cord-010570-ytv7dwr0	77	8	therapeutic	therapeutic	JJ
cord-010570-ytv7dwr0	77	9	dose	dose	NN
cord-010570-ytv7dwr0	77	10	of	of	IN
cord-010570-ytv7dwr0	77	11	approximately	approximately	RB
cord-010570-ytv7dwr0	77	12	ten	ten	CD
cord-010570-ytv7dwr0	77	13	cubic	cubic	JJ
cord-010570-ytv7dwr0	77	14	centimeters	centimeter	NNS
cord-010570-ytv7dwr0	77	15	.	.	.
cord-010570-ytv7dwr0	78	1	The	the	DT
cord-010570-ytv7dwr0	78	2	data	datum	NNS
cord-010570-ytv7dwr0	78	3	cited	cite	VBD
cord-010570-ytv7dwr0	78	4	were	be	VBD
cord-010570-ytv7dwr0	78	5	published	publish	VBN
cord-010570-ytv7dwr0	78	6	in	in	IN
cord-010570-ytv7dwr0	78	7	[	[	-LRB-
cord-010570-ytv7dwr0	78	8	37	37	CD
cord-010570-ytv7dwr0	78	9	]	]	-RRB-
cord-010570-ytv7dwr0	78	10	.	.	.
cord-010570-ytv7dwr0	79	1	patients	patient	NNS
cord-010570-ytv7dwr0	79	2	,	,	,
cord-010570-ytv7dwr0	79	3	and	and	CC
cord-010570-ytv7dwr0	79	4	younger	young	JJR
cord-010570-ytv7dwr0	79	5	patients	patient	NNS
cord-010570-ytv7dwr0	79	6	who	who	WP
cord-010570-ytv7dwr0	79	7	received	receive	VBD
cord-010570-ytv7dwr0	79	8	serum	serum	NN
cord-010570-ytv7dwr0	79	9	recovered	recover	VBD
cord-010570-ytv7dwr0	79	10	faster	fast	RBR
cord-010570-ytv7dwr0	79	11	than	than	IN
cord-010570-ytv7dwr0	79	12	those	those	DT
cord-010570-ytv7dwr0	79	13	who	who	WP
cord-010570-ytv7dwr0	79	14	received	receive	VBD
cord-010570-ytv7dwr0	79	15	antimicrobials	antimicrobial	NNS
cord-010570-ytv7dwr0	79	16	[	[	-LRB-
cord-010570-ytv7dwr0	79	17	51	51	CD
cord-010570-ytv7dwr0	79	18	]	]	-RRB-
cord-010570-ytv7dwr0	79	19	.	.	.
cord-010570-ytv7dwr0	80	1	In	in	IN
cord-010570-ytv7dwr0	80	2	the	the	DT
cord-010570-ytv7dwr0	80	3	early	early	JJ
cord-010570-ytv7dwr0	80	4	days	day	NNS
cord-010570-ytv7dwr0	80	5	of	of	IN
cord-010570-ytv7dwr0	80	6	the	the	DT
cord-010570-ytv7dwr0	80	7	antibiotic	antibiotic	JJ
cord-010570-ytv7dwr0	80	8	era	era	NN
cord-010570-ytv7dwr0	80	9	there	there	EX
cord-010570-ytv7dwr0	80	10	was	be	VBD
cord-010570-ytv7dwr0	80	11	interest	interest	NN
cord-010570-ytv7dwr0	80	12	in	in	IN
cord-010570-ytv7dwr0	80	13	using	use	VBG
cord-010570-ytv7dwr0	80	14	combination	combination	NN
cord-010570-ytv7dwr0	80	15	therapies	therapy	NNS
cord-010570-ytv7dwr0	80	16	with	with	IN
cord-010570-ytv7dwr0	80	17	antibiotics	antibiotic	NNS
cord-010570-ytv7dwr0	80	18	and	and	CC
cord-010570-ytv7dwr0	80	19	serum	serum	NN
cord-010570-ytv7dwr0	80	20	.	.	.
cord-010570-ytv7dwr0	81	1	Sulfonamides	sulfonamide	NNS
cord-010570-ytv7dwr0	81	2	and	and	CC
cord-010570-ytv7dwr0	81	3	serum	serum	NN
cord-010570-ytv7dwr0	81	4	had	have	VBD
cord-010570-ytv7dwr0	81	5	a	a	DT
cord-010570-ytv7dwr0	81	6	synergistic	synergistic	JJ
cord-010570-ytv7dwr0	81	7	or	or	CC
cord-010570-ytv7dwr0	81	8	additive	additive	NN
cord-010570-ytv7dwr0	81	9	effect	effect	NN
cord-010570-ytv7dwr0	81	10	against	against	IN
cord-010570-ytv7dwr0	81	11	Streptococcus	streptococcus	NN
cord-010570-ytv7dwr0	81	12	pneumoniae	pneumoniae	NN
cord-010570-ytv7dwr0	81	13	[	[	-LRB-
cord-010570-ytv7dwr0	81	14	52	52	CD
cord-010570-ytv7dwr0	81	15	]	]	-RRB-
cord-010570-ytv7dwr0	82	1	[	[	-LRB-
cord-010570-ytv7dwr0	82	2	53	53	CD
cord-010570-ytv7dwr0	82	3	]	]	-RRB-
cord-010570-ytv7dwr0	83	1	[	[	-LRB-
cord-010570-ytv7dwr0	83	2	54	54	CD
cord-010570-ytv7dwr0	83	3	]	]	-RRB-
cord-010570-ytv7dwr0	84	1	[	[	-LRB-
cord-010570-ytv7dwr0	84	2	55	55	CD
cord-010570-ytv7dwr0	84	3	]	]	-RRB-
cord-010570-ytv7dwr0	84	4	,	,	,
cord-010570-ytv7dwr0	84	5	streptococci	streptococcus	NNS
cord-010570-ytv7dwr0	84	6	[	[	-LRB-
cord-010570-ytv7dwr0	84	7	56	56	CD
cord-010570-ytv7dwr0	84	8	]	]	-RRB-
cord-010570-ytv7dwr0	84	9	,	,	,
cord-010570-ytv7dwr0	84	10	and	and	CC
cord-010570-ytv7dwr0	84	11	meningococci	meningococci	NNS
cord-010570-ytv7dwr0	84	12	[	[	-LRB-
cord-010570-ytv7dwr0	84	13	57	57	CD
cord-010570-ytv7dwr0	84	14	]	]	-RRB-
cord-010570-ytv7dwr0	84	15	.	.	.
cord-010570-ytv7dwr0	85	1	The	the	DT
cord-010570-ytv7dwr0	85	2	finding	finding	NN
cord-010570-ytv7dwr0	85	3	that	that	IN
cord-010570-ytv7dwr0	85	4	sulfonamides	sulfonamide	NNS
cord-010570-ytv7dwr0	85	5	made	make	VBD
cord-010570-ytv7dwr0	85	6	pneumococci	pneumococcus	NNS
cord-010570-ytv7dwr0	85	7	more	more	RBR
cord-010570-ytv7dwr0	85	8	susceptible	susceptible	JJ
cord-010570-ytv7dwr0	85	9	to	to	IN
cord-010570-ytv7dwr0	85	10	antibody	antibody	NN
cord-010570-ytv7dwr0	85	11	-	-	HYPH
cord-010570-ytv7dwr0	85	12	mediated	mediate	VBN
cord-010570-ytv7dwr0	85	13	phagocytosis	phagocytosis	NN
cord-010570-ytv7dwr0	85	14	supported	support	VBD
cord-010570-ytv7dwr0	85	15	the	the	DT
cord-010570-ytv7dwr0	85	16	idea	idea	NN
cord-010570-ytv7dwr0	85	17	of	of	IN
cord-010570-ytv7dwr0	85	18	combination	combination	NN
cord-010570-ytv7dwr0	85	19	therapy	therapy	NN
cord-010570-ytv7dwr0	85	20	[	[	-LRB-
cord-010570-ytv7dwr0	85	21	58	58	CD
cord-010570-ytv7dwr0	85	22	]	]	-RRB-
cord-010570-ytv7dwr0	85	23	.	.	.
cord-010570-ytv7dwr0	86	1	It	-PRON-	PRP
cord-010570-ytv7dwr0	86	2	was	be	VBD
cord-010570-ytv7dwr0	86	3	similarly	similarly	RB
cord-010570-ytv7dwr0	86	4	recognized	recognize	VBN
cord-010570-ytv7dwr0	86	5	that	that	IN
cord-010570-ytv7dwr0	86	6	sulfonamides	sulfonamide	NNS
cord-010570-ytv7dwr0	86	7	,	,	,
cord-010570-ytv7dwr0	86	8	unlike	unlike	IN
cord-010570-ytv7dwr0	86	9	antibody	antibody	NN
cord-010570-ytv7dwr0	86	10	,	,	,
cord-010570-ytv7dwr0	86	11	did	do	VBD
cord-010570-ytv7dwr0	86	12	not	not	RB
cord-010570-ytv7dwr0	86	13	neutralize	neutralize	VB
cord-010570-ytv7dwr0	86	14	bacterial	bacterial	JJ
cord-010570-ytv7dwr0	86	15	toxins	toxin	NNS
cord-010570-ytv7dwr0	86	16	or	or	CC
cord-010570-ytv7dwr0	86	17	modify	modify	VB
cord-010570-ytv7dwr0	86	18	the	the	DT
cord-010570-ytv7dwr0	86	19	course	course	NN
cord-010570-ytv7dwr0	86	20	of	of	IN
cord-010570-ytv7dwr0	86	21	disease	disease	NN
cord-010570-ytv7dwr0	86	22	caused	cause	VBN
cord-010570-ytv7dwr0	86	23	by	by	IN
cord-010570-ytv7dwr0	86	24	diphtheria	diphtheria	NN
cord-010570-ytv7dwr0	86	25	or	or	CC
cord-010570-ytv7dwr0	86	26	tetanus	tetanus	NN
cord-010570-ytv7dwr0	86	27	toxins	toxin	NNS
cord-010570-ytv7dwr0	86	28	[	[	-LRB-
cord-010570-ytv7dwr0	86	29	59	59	CD
cord-010570-ytv7dwr0	86	30	]	]	-RRB-
cord-010570-ytv7dwr0	86	31	.	.	.
cord-010570-ytv7dwr0	87	1	Combination	combination	NN
cord-010570-ytv7dwr0	87	2	therapy	therapy	NN
cord-010570-ytv7dwr0	87	3	was	be	VBD
cord-010570-ytv7dwr0	87	4	recommended	recommend	VBN
cord-010570-ytv7dwr0	87	5	for	for	IN
cord-010570-ytv7dwr0	87	6	scarlet	scarlet	JJ
cord-010570-ytv7dwr0	87	7	fever	fever	NN
cord-010570-ytv7dwr0	87	8	[	[	-LRB-
cord-010570-ytv7dwr0	87	9	60	60	CD
cord-010570-ytv7dwr0	87	10	]	]	-RRB-
cord-010570-ytv7dwr0	88	1	,	,	,
cord-010570-ytv7dwr0	88	2	pneumococcal	pneumococcal	JJ
cord-010570-ytv7dwr0	88	3	pneumonia	pneumonia	NN
cord-010570-ytv7dwr0	88	4	[	[	-LRB-
cord-010570-ytv7dwr0	88	5	44	44	CD
cord-010570-ytv7dwr0	88	6	,	,	,
cord-010570-ytv7dwr0	88	7	54	54	CD
cord-010570-ytv7dwr0	88	8	,	,	,
cord-010570-ytv7dwr0	88	9	61	61	CD
cord-010570-ytv7dwr0	88	10	]	]	-RRB-
cord-010570-ytv7dwr0	88	11	,	,	,
cord-010570-ytv7dwr0	88	12	whooping	whooping	JJ
cord-010570-ytv7dwr0	88	13	cough	cough	NN
cord-010570-ytv7dwr0	88	14	[	[	-LRB-
cord-010570-ytv7dwr0	88	15	20	20	CD
cord-010570-ytv7dwr0	88	16	]	]	-RRB-
cord-010570-ytv7dwr0	88	17	and	and	CC
cord-010570-ytv7dwr0	88	18	meningitis	meningitis	NN
cord-010570-ytv7dwr0	88	19	due	due	IN
cord-010570-ytv7dwr0	88	20	to	to	IN
cord-010570-ytv7dwr0	88	21	pneumococcus	pneumococcus	NNP
cord-010570-ytv7dwr0	88	22	[	[	-LRB-
cord-010570-ytv7dwr0	88	23	8	8	CD
cord-010570-ytv7dwr0	88	24	,	,	,
cord-010570-ytv7dwr0	88	25	62	62	CD
cord-010570-ytv7dwr0	88	26	]	]	-RRB-
cord-010570-ytv7dwr0	88	27	,	,	,
cord-010570-ytv7dwr0	88	28	meningococcus	meningococcus	NNP
cord-010570-ytv7dwr0	88	29	[	[	-LRB-
cord-010570-ytv7dwr0	88	30	8	8	CD
cord-010570-ytv7dwr0	88	31	,	,	,
cord-010570-ytv7dwr0	88	32	50	50	CD
cord-010570-ytv7dwr0	88	33	,	,	,
cord-010570-ytv7dwr0	88	34	63	63	CD
cord-010570-ytv7dwr0	88	35	,	,	,
cord-010570-ytv7dwr0	88	36	64	64	CD
cord-010570-ytv7dwr0	88	37	]	]	-RRB-
cord-010570-ytv7dwr0	88	38	,	,	,
cord-010570-ytv7dwr0	88	39	or	or	CC
cord-010570-ytv7dwr0	88	40	H.	h.	NN
cord-010570-ytv7dwr0	88	41	influenzae	influenzae	NN
cord-010570-ytv7dwr0	88	42	[	[	-LRB-
cord-010570-ytv7dwr0	88	43	8	8	CD
cord-010570-ytv7dwr0	88	44	]	]	-RRB-
cord-010570-ytv7dwr0	88	45	.	.	.
cord-010570-ytv7dwr0	89	1	However	however	RB
cord-010570-ytv7dwr0	89	2	,	,	,
cord-010570-ytv7dwr0	89	3	the	the	DT
cord-010570-ytv7dwr0	89	4	side	side	NN
cord-010570-ytv7dwr0	89	5	effects	effect	NNS
cord-010570-ytv7dwr0	89	6	of	of	IN
cord-010570-ytv7dwr0	89	7	serum	serum	NN
cord-010570-ytv7dwr0	89	8	made	make	VBD
cord-010570-ytv7dwr0	89	9	the	the	DT
cord-010570-ytv7dwr0	89	10	potential	potential	JJ
cord-010570-ytv7dwr0	89	11	benefits	benefit	NNS
cord-010570-ytv7dwr0	89	12	of	of	IN
cord-010570-ytv7dwr0	89	13	combination	combination	NN
cord-010570-ytv7dwr0	89	14	therapy	therapy	NN
cord-010570-ytv7dwr0	89	15	marginal	marginal	JJ
cord-010570-ytv7dwr0	89	16	[	[	-LRB-
cord-010570-ytv7dwr0	89	17	50	50	CD
cord-010570-ytv7dwr0	89	18	]	]	-RRB-
cord-010570-ytv7dwr0	89	19	.	.	.
cord-010570-ytv7dwr0	90	1	In	in	IN
cord-010570-ytv7dwr0	90	2	summary	summary	NN
cord-010570-ytv7dwr0	90	3	,	,	,
cord-010570-ytv7dwr0	90	4	serum	serum	NN
cord-010570-ytv7dwr0	90	5	therapy	therapy	NN
cord-010570-ytv7dwr0	90	6	was	be	VBD
cord-010570-ytv7dwr0	90	7	abandoned	abandon	VBN
cord-010570-ytv7dwr0	90	8	because	because	IN
cord-010570-ytv7dwr0	90	9	of	of	IN
cord-010570-ytv7dwr0	90	10	toxicity	toxicity	NN
cord-010570-ytv7dwr0	90	11	,	,	,
cord-010570-ytv7dwr0	90	12	difficulty	difficulty	NN
cord-010570-ytv7dwr0	90	13	in	in	IN
cord-010570-ytv7dwr0	90	14	administration	administration	NN
cord-010570-ytv7dwr0	90	15	,	,	,
cord-010570-ytv7dwr0	90	16	narrow	narrow	JJ
cord-010570-ytv7dwr0	90	17	specificity	specificity	NN
cord-010570-ytv7dwr0	90	18	,	,	,
cord-010570-ytv7dwr0	90	19	lot	lot	NN
cord-010570-ytv7dwr0	90	20	-	-	HYPH
cord-010570-ytv7dwr0	90	21	to	to	IN
cord-010570-ytv7dwr0	90	22	-	-	HYPH
cord-010570-ytv7dwr0	90	23	lot	lot	NN
cord-010570-ytv7dwr0	90	24	variation	variation	NN
cord-010570-ytv7dwr0	90	25	,	,	,
cord-010570-ytv7dwr0	90	26	and	and	CC
cord-010570-ytv7dwr0	90	27	expense	expense	NN
cord-010570-ytv7dwr0	90	28	.	.	.
cord-010570-ytv7dwr0	91	1	Chemotherapy	chemotherapy	NN
cord-010570-ytv7dwr0	91	2	was	be	VBD
cord-010570-ytv7dwr0	91	3	less	less	RBR
cord-010570-ytv7dwr0	91	4	toxic	toxic	JJ
cord-010570-ytv7dwr0	91	5	and	and	CC
cord-010570-ytv7dwr0	91	6	easier	easy	JJR
cord-010570-ytv7dwr0	91	7	to	to	TO
cord-010570-ytv7dwr0	91	8	use	use	VB
cord-010570-ytv7dwr0	91	9	,	,	,
cord-010570-ytv7dwr0	91	10	lots	lot	NNS
cord-010570-ytv7dwr0	91	11	were	be	VBD
cord-010570-ytv7dwr0	91	12	more	more	RBR
cord-010570-ytv7dwr0	91	13	consistent	consistent	JJ
cord-010570-ytv7dwr0	91	14	,	,	,
cord-010570-ytv7dwr0	91	15	and	and	CC
cord-010570-ytv7dwr0	91	16	it	-PRON-	PRP
cord-010570-ytv7dwr0	91	17	was	be	VBD
cord-010570-ytv7dwr0	91	18	more	more	RBR
cord-010570-ytv7dwr0	91	19	effective	effective	JJ
cord-010570-ytv7dwr0	91	20	in	in	IN
cord-010570-ytv7dwr0	91	21	eradicating	eradicate	VBG
cord-010570-ytv7dwr0	91	22	infection	infection	NN
cord-010570-ytv7dwr0	91	23	.	.	.
cord-010570-ytv7dwr0	92	1	In	in	IN
cord-010570-ytv7dwr0	92	2	addition	addition	NN
cord-010570-ytv7dwr0	92	3	,	,	,
cord-010570-ytv7dwr0	92	4	there	there	EX
cord-010570-ytv7dwr0	92	5	was	be	VBD
cord-010570-ytv7dwr0	92	6	no	no	DT
cord-010570-ytv7dwr0	92	7	need	need	NN
cord-010570-ytv7dwr0	92	8	for	for	IN
cord-010570-ytv7dwr0	92	9	strain	strain	NN
cord-010570-ytv7dwr0	92	10	typing	type	VBG
cord-010570-ytv7dwr0	92	11	with	with	IN
cord-010570-ytv7dwr0	92	12	chemotherapy	chemotherapy	NN
cord-010570-ytv7dwr0	92	13	.	.	.
cord-010570-ytv7dwr0	93	1	However	however	RB
cord-010570-ytv7dwr0	93	2	,	,	,
cord-010570-ytv7dwr0	93	3	it	-PRON-	PRP
cord-010570-ytv7dwr0	93	4	is	be	VBZ
cord-010570-ytv7dwr0	93	5	ironic	ironic	JJ
cord-010570-ytv7dwr0	93	6	that	that	IN
cord-010570-ytv7dwr0	93	7	the	the	DT
cord-010570-ytv7dwr0	93	8	broad	broad	JJ
cord-010570-ytv7dwr0	93	9	antimicrobial	antimicrobial	JJ
cord-010570-ytv7dwr0	93	10	activity	activity	NN
cord-010570-ytv7dwr0	93	11	of	of	IN
cord-010570-ytv7dwr0	93	12	these	these	DT
cord-010570-ytv7dwr0	93	13	drugs	drug	NNS
cord-010570-ytv7dwr0	93	14	used	use	VBN
cord-010570-ytv7dwr0	93	15	for	for	IN
cord-010570-ytv7dwr0	93	16	chemotherapy	chemotherapy	NN
cord-010570-ytv7dwr0	93	17	might	may	MD
cord-010570-ytv7dwr0	93	18	have	have	VB
cord-010570-ytv7dwr0	93	19	contributed	contribute	VBN
cord-010570-ytv7dwr0	93	20	to	to	IN
cord-010570-ytv7dwr0	93	21	widespread	widespread	JJ
cord-010570-ytv7dwr0	93	22	resistance	resistance	NN
cord-010570-ytv7dwr0	93	23	,	,	,
cord-010570-ytv7dwr0	93	24	and	and	CC
cord-010570-ytv7dwr0	93	25	today	today	NN
cord-010570-ytv7dwr0	93	26	susceptibility	susceptibility	NN
cord-010570-ytv7dwr0	93	27	testing	testing	NN
cord-010570-ytv7dwr0	93	28	is	be	VBZ
cord-010570-ytv7dwr0	93	29	essential	essential	JJ
cord-010570-ytv7dwr0	93	30	to	to	IN
cord-010570-ytv7dwr0	93	31	the	the	DT
cord-010570-ytv7dwr0	93	32	selection	selection	NN
cord-010570-ytv7dwr0	93	33	of	of	IN
cord-010570-ytv7dwr0	93	34	appropriate	appropriate	JJ
cord-010570-ytv7dwr0	93	35	antimicrobial	antimicrobial	JJ
cord-010570-ytv7dwr0	93	36	drugs	drug	NNS
cord-010570-ytv7dwr0	93	37	.	.	.
cord-010570-ytv7dwr0	94	1	Although	although	IN
cord-010570-ytv7dwr0	94	2	antibodies	antibody	NNS
cord-010570-ytv7dwr0	94	3	are	be	VBP
cord-010570-ytv7dwr0	94	4	no	no	RB
cord-010570-ytv7dwr0	94	5	longer	long	RBR
cord-010570-ytv7dwr0	94	6	used	use	VBN
cord-010570-ytv7dwr0	94	7	directly	directly	RB
cord-010570-ytv7dwr0	94	8	as	as	IN
cord-010570-ytv7dwr0	94	9	antibacterial	antibacterial	JJ
cord-010570-ytv7dwr0	94	10	drugs	drug	NNS
cord-010570-ytv7dwr0	94	11	,	,	,
cord-010570-ytv7dwr0	94	12	they	-PRON-	PRP
cord-010570-ytv7dwr0	94	13	continue	continue	VBP
cord-010570-ytv7dwr0	94	14	to	to	TO
cord-010570-ytv7dwr0	94	15	be	be	VB
cord-010570-ytv7dwr0	94	16	used	use	VBN
cord-010570-ytv7dwr0	94	17	in	in	IN
cord-010570-ytv7dwr0	94	18	infectious	infectious	JJ
cord-010570-ytv7dwr0	94	19	diseases	disease	NNS
cord-010570-ytv7dwr0	94	20	(	(	-LRB-
cord-010570-ytv7dwr0	94	21	for	for	IN
cord-010570-ytv7dwr0	94	22	recent	recent	JJ
cord-010570-ytv7dwr0	94	23	reviews	review	NNS
cord-010570-ytv7dwr0	94	24	see	see	VBP
cord-010570-ytv7dwr0	94	25	[	[	-LRB-
cord-010570-ytv7dwr0	94	26	65	65	CD
cord-010570-ytv7dwr0	94	27	]	]	-RRB-
cord-010570-ytv7dwr0	95	1	[	[	-LRB-
cord-010570-ytv7dwr0	95	2	66	66	CD
cord-010570-ytv7dwr0	95	3	]	]	-RRB-
cord-010570-ytv7dwr0	95	4	[	[	-LRB-
cord-010570-ytv7dwr0	95	5	67	67	CD
cord-010570-ytv7dwr0	95	6	]	]	-RRB-
cord-010570-ytv7dwr0	95	7	)	)	-RRB-
cord-010570-ytv7dwr0	95	8	.	.	.
cord-010570-ytv7dwr0	96	1	The	the	DT
cord-010570-ytv7dwr0	96	2	majority	majority	NN
cord-010570-ytv7dwr0	96	3	of	of	IN
cord-010570-ytv7dwr0	96	4	antibody	antibody	NN
cord-010570-ytv7dwr0	96	5	preparations	preparation	NNS
cord-010570-ytv7dwr0	96	6	are	be	VBP
cord-010570-ytv7dwr0	96	7	now	now	RB
cord-010570-ytv7dwr0	96	8	human	human	JJ
cord-010570-ytv7dwr0	96	9	.	.	.
cord-010570-ytv7dwr0	97	1	Antibody	Antibody	NNP
cord-010570-ytv7dwr0	97	2	administration	administration	NN
cord-010570-ytv7dwr0	97	3	reduces	reduce	VBZ
cord-010570-ytv7dwr0	97	4	infection	infection	NN
cord-010570-ytv7dwr0	97	5	in	in	IN
cord-010570-ytv7dwr0	97	6	individuals	individual	NNS
cord-010570-ytv7dwr0	97	7	with	with	IN
cord-010570-ytv7dwr0	97	8	immunodeficiencies	immunodeficiency	NNS
cord-010570-ytv7dwr0	97	9	[	[	-LRB-
cord-010570-ytv7dwr0	97	10	65	65	CD
cord-010570-ytv7dwr0	97	11	]	]	-RRB-
cord-010570-ytv7dwr0	98	1	[	[	-LRB-
cord-010570-ytv7dwr0	98	2	66	66	CD
cord-010570-ytv7dwr0	98	3	]	]	-RRB-
cord-010570-ytv7dwr0	99	1	[	[	-LRB-
cord-010570-ytv7dwr0	99	2	67	67	CD
cord-010570-ytv7dwr0	99	3	]	]	-RRB-
cord-010570-ytv7dwr0	100	1	[	[	-LRB-
cord-010570-ytv7dwr0	100	2	68	68	CD
cord-010570-ytv7dwr0	100	3	]	]	-RRB-
cord-010570-ytv7dwr0	100	4	and	and	CC
cord-010570-ytv7dwr0	100	5	is	be	VBZ
cord-010570-ytv7dwr0	100	6	effective	effective	JJ
cord-010570-ytv7dwr0	100	7	for	for	IN
cord-010570-ytv7dwr0	100	8	postexposure	postexposure	NN
cord-010570-ytv7dwr0	100	9	prophylaxis	prophylaxis	NN
cord-010570-ytv7dwr0	100	10	against	against	IN
cord-010570-ytv7dwr0	100	11	measles	measle	NNS
cord-010570-ytv7dwr0	100	12	,	,	,
cord-010570-ytv7dwr0	100	13	hepatitis	hepatitis	NNP
cord-010570-ytv7dwr0	100	14	A	A	NNP
cord-010570-ytv7dwr0	100	15	and	and	CC
cord-010570-ytv7dwr0	100	16	B	b	NN
cord-010570-ytv7dwr0	100	17	,	,	,
cord-010570-ytv7dwr0	100	18	rabies	rabie	NNS
cord-010570-ytv7dwr0	100	19	,	,	,
cord-010570-ytv7dwr0	100	20	and	and	CC
cord-010570-ytv7dwr0	100	21	varicella	varicella	NN
cord-010570-ytv7dwr0	100	22	viruses	virus	NNS
cord-010570-ytv7dwr0	100	23	.	.	.
cord-010570-ytv7dwr0	101	1	Specific	specific	JJ
cord-010570-ytv7dwr0	101	2	antibody	antibody	NN
cord-010570-ytv7dwr0	101	3	is	be	VBZ
cord-010570-ytv7dwr0	101	4	used	use	VBN
cord-010570-ytv7dwr0	101	5	for	for	IN
cord-010570-ytv7dwr0	101	6	the	the	DT
cord-010570-ytv7dwr0	101	7	treatment	treatment	NN
cord-010570-ytv7dwr0	101	8	of	of	IN
cord-010570-ytv7dwr0	101	9	botulism	botulism	NN
cord-010570-ytv7dwr0	101	10	[	[	-LRB-
cord-010570-ytv7dwr0	101	11	22	22	CD
cord-010570-ytv7dwr0	101	12	]	]	-RRB-
cord-010570-ytv7dwr0	101	13	,	,	,
cord-010570-ytv7dwr0	101	14	diphtheria	diphtheria	NN
cord-010570-ytv7dwr0	101	15	[	[	-LRB-
cord-010570-ytv7dwr0	101	16	40	40	CD
cord-010570-ytv7dwr0	101	17	]	]	-RRB-
cord-010570-ytv7dwr0	101	18	,	,	,
cord-010570-ytv7dwr0	101	19	tetanus	tetanus	JJ
cord-010570-ytv7dwr0	101	20	[	[	-LRB-
cord-010570-ytv7dwr0	101	21	22	22	CD
cord-010570-ytv7dwr0	101	22	]	]	-RRB-
cord-010570-ytv7dwr0	101	23	,	,	,
cord-010570-ytv7dwr0	101	24	snake	snake	NN
cord-010570-ytv7dwr0	101	25	bites	bite	NNS
cord-010570-ytv7dwr0	101	26	[	[	-LRB-
cord-010570-ytv7dwr0	101	27	69	69	CD
cord-010570-ytv7dwr0	101	28	]	]	-RRB-
cord-010570-ytv7dwr0	101	29	,	,	,
cord-010570-ytv7dwr0	101	30	and	and	CC
cord-010570-ytv7dwr0	101	31	spider	spider	NN
cord-010570-ytv7dwr0	101	32	stings	sting	NNS
cord-010570-ytv7dwr0	101	33	[	[	-LRB-
cord-010570-ytv7dwr0	101	34	70	70	CD
cord-010570-ytv7dwr0	101	35	]	]	-RRB-
cord-010570-ytv7dwr0	101	36	.	.	.
cord-010570-ytv7dwr0	102	1	Passive	Passive	NNP
cord-010570-ytv7dwr0	102	2	antibody	antibody	NNP
cord-010570-ytv7dwr0	102	3	administration	administration	NN
cord-010570-ytv7dwr0	102	4	has	have	VBZ
cord-010570-ytv7dwr0	102	5	been	be	VBN
cord-010570-ytv7dwr0	102	6	used	use	VBN
cord-010570-ytv7dwr0	102	7	for	for	IN
cord-010570-ytv7dwr0	102	8	prophylaxis	prophylaxis	NN
cord-010570-ytv7dwr0	102	9	and/or	and/or	CC
cord-010570-ytv7dwr0	102	10	therapy	therapy	NN
cord-010570-ytv7dwr0	102	11	of	of	IN
cord-010570-ytv7dwr0	102	12	several	several	JJ
cord-010570-ytv7dwr0	102	13	viral	viral	JJ
cord-010570-ytv7dwr0	102	14	infections	infection	NNS
cord-010570-ytv7dwr0	102	15	,	,	,
cord-010570-ytv7dwr0	102	16	including	include	VBG
cord-010570-ytv7dwr0	102	17	cytomegalovirus	cytomegalovirus	NNP
cord-010570-ytv7dwr0	102	18	(	(	-LRB-
cord-010570-ytv7dwr0	102	19	CMV	CMV	NNP
cord-010570-ytv7dwr0	102	20	)	)	-RRB-
cord-010570-ytv7dwr0	102	21	[	[	-LRB-
cord-010570-ytv7dwr0	102	22	71	71	CD
cord-010570-ytv7dwr0	102	23	,	,	,
cord-010570-ytv7dwr0	102	24	72	72	CD
cord-010570-ytv7dwr0	102	25	]	]	-RRB-
cord-010570-ytv7dwr0	102	26	,	,	,
cord-010570-ytv7dwr0	102	27	rotavirus	rotavirus	JJ
cord-010570-ytv7dwr0	102	28	[	[	-LRB-
cord-010570-ytv7dwr0	102	29	73	73	CD
cord-010570-ytv7dwr0	102	30	]	]	-RRB-
cord-010570-ytv7dwr0	102	31	,	,	,
cord-010570-ytv7dwr0	102	32	Lassa	Lassa	NNP
cord-010570-ytv7dwr0	102	33	virus	virus	NN
cord-010570-ytv7dwr0	102	34	[	[	-LRB-
cord-010570-ytv7dwr0	102	35	74	74	CD
cord-010570-ytv7dwr0	102	36	]	]	-RRB-
cord-010570-ytv7dwr0	102	37	,	,	.
cord-010570-ytv7dwr0	103	1	varicella	varicella	NN
cord-010570-ytv7dwr0	103	2	[	[	-LRB-
cord-010570-ytv7dwr0	103	3	75	75	CD
cord-010570-ytv7dwr0	103	4	]	]	-RRB-
cord-010570-ytv7dwr0	103	5	,	,	,
cord-010570-ytv7dwr0	103	6	enterovirus	enterovirus	NN
cord-010570-ytv7dwr0	103	7	[	[	-LRB-
cord-010570-ytv7dwr0	103	8	76	76	CD
cord-010570-ytv7dwr0	103	9	,	,	,
cord-010570-ytv7dwr0	103	10	77	77	CD
cord-010570-ytv7dwr0	103	11	]	]	-RRB-
cord-010570-ytv7dwr0	103	12	,	,	,
cord-010570-ytv7dwr0	103	13	and	and	CC
cord-010570-ytv7dwr0	103	14	parvovirus	parvovirus	NN
cord-010570-ytv7dwr0	103	15	B19	B19	NNP
cord-010570-ytv7dwr0	103	16	infections	infection	NNS
cord-010570-ytv7dwr0	103	17	[	[	-LRB-
cord-010570-ytv7dwr0	103	18	78	78	CD
cord-010570-ytv7dwr0	103	19	]	]	-RRB-
cord-010570-ytv7dwr0	103	20	.	.	.
cord-010570-ytv7dwr0	104	1	In	in	IN
cord-010570-ytv7dwr0	104	2	recent	recent	JJ
cord-010570-ytv7dwr0	104	3	years	year	NNS
cord-010570-ytv7dwr0	104	4	,	,	,
cord-010570-ytv7dwr0	104	5	there	there	EX
cord-010570-ytv7dwr0	104	6	has	have	VBZ
cord-010570-ytv7dwr0	104	7	been	be	VBN
cord-010570-ytv7dwr0	104	8	renewed	renew	VBN
cord-010570-ytv7dwr0	104	9	interest	interest	NN
cord-010570-ytv7dwr0	104	10	in	in	IN
cord-010570-ytv7dwr0	104	11	the	the	DT
cord-010570-ytv7dwr0	104	12	use	use	NN
cord-010570-ytv7dwr0	104	13	of	of	IN
cord-010570-ytv7dwr0	104	14	antibody	antibody	NN
cord-010570-ytv7dwr0	104	15	preparations	preparation	NNS
cord-010570-ytv7dwr0	104	16	to	to	TO
cord-010570-ytv7dwr0	104	17	prevent	prevent	VB
cord-010570-ytv7dwr0	104	18	infection	infection	NN
cord-010570-ytv7dwr0	104	19	in	in	IN
cord-010570-ytv7dwr0	104	20	high	high	JJ
cord-010570-ytv7dwr0	104	21	-	-	HYPH
cord-010570-ytv7dwr0	104	22	risk	risk	NN
cord-010570-ytv7dwr0	104	23	groups	group	NNS
cord-010570-ytv7dwr0	104	24	.	.	.
cord-010570-ytv7dwr0	105	1	Intravenous	intravenous	JJ
cord-010570-ytv7dwr0	105	2	administration	administration	NN
cord-010570-ytv7dwr0	105	3	of	of	IN
cord-010570-ytv7dwr0	105	4	polyclonal	polyclonal	JJ
cord-010570-ytv7dwr0	105	5	antibody	antibody	NN
cord-010570-ytv7dwr0	105	6	has	have	VBZ
cord-010570-ytv7dwr0	105	7	been	be	VBN
cord-010570-ytv7dwr0	105	8	reported	report	VBN
cord-010570-ytv7dwr0	105	9	to	to	TO
cord-010570-ytv7dwr0	105	10	reduce	reduce	VB
cord-010570-ytv7dwr0	105	11	the	the	DT
cord-010570-ytv7dwr0	105	12	number	number	NN
cord-010570-ytv7dwr0	105	13	of	of	IN
cord-010570-ytv7dwr0	105	14	infections	infection	NNS
cord-010570-ytv7dwr0	105	15	in	in	IN
cord-010570-ytv7dwr0	105	16	patients	patient	NNS
cord-010570-ytv7dwr0	105	17	with	with	IN
cord-010570-ytv7dwr0	105	18	AIDS	AIDS	NNP
cord-010570-ytv7dwr0	105	19	[	[	-LRB-
cord-010570-ytv7dwr0	105	20	79	79	CD
cord-010570-ytv7dwr0	105	21	]	]	-RRB-
cord-010570-ytv7dwr0	106	1	[	[	-LRB-
cord-010570-ytv7dwr0	106	2	80	80	CD
cord-010570-ytv7dwr0	106	3	]	]	-RRB-
cord-010570-ytv7dwr0	107	1	[	[	-LRB-
cord-010570-ytv7dwr0	107	2	81	81	CD
cord-010570-ytv7dwr0	107	3	]	]	-RRB-
cord-010570-ytv7dwr0	107	4	,	,	,
cord-010570-ytv7dwr0	107	5	patients	patient	NNS
cord-010570-ytv7dwr0	107	6	in	in	IN
cord-010570-ytv7dwr0	107	7	surgical	surgical	JJ
cord-010570-ytv7dwr0	107	8	intensive	intensive	JJ
cord-010570-ytv7dwr0	107	9	care	care	NN
cord-010570-ytv7dwr0	107	10	units	unit	NNS
cord-010570-ytv7dwr0	107	11	[	[	-LRB-
cord-010570-ytv7dwr0	107	12	82	82	CD
cord-010570-ytv7dwr0	107	13	]	]	-RRB-
cord-010570-ytv7dwr0	107	14	,	,	,
cord-010570-ytv7dwr0	107	15	organ	organ	NN
cord-010570-ytv7dwr0	107	16	transplant	transplant	NN
cord-010570-ytv7dwr0	107	17	recipients	recipient	NNS
cord-010570-ytv7dwr0	107	18	[	[	-LRB-
cord-010570-ytv7dwr0	107	19	83	83	CD
cord-010570-ytv7dwr0	107	20	]	]	-RRB-
cord-010570-ytv7dwr0	107	21	,	,	,
cord-010570-ytv7dwr0	107	22	and	and	CC
cord-010570-ytv7dwr0	107	23	neonates	neonate	NNS
cord-010570-ytv7dwr0	107	24	[	[	-LRB-
cord-010570-ytv7dwr0	107	25	84	84	CD
cord-010570-ytv7dwr0	107	26	,	,	,
cord-010570-ytv7dwr0	107	27	85	85	CD
cord-010570-ytv7dwr0	107	28	]	]	-RRB-
cord-010570-ytv7dwr0	107	29	(	(	-LRB-
cord-010570-ytv7dwr0	107	30	for	for	IN
cord-010570-ytv7dwr0	107	31	critical	critical	JJ
cord-010570-ytv7dwr0	107	32	reviews	review	NNS
cord-010570-ytv7dwr0	107	33	and	and	CC
cord-010570-ytv7dwr0	107	34	commentary	commentary	NN
cord-010570-ytv7dwr0	107	35	on	on	IN
cord-010570-ytv7dwr0	107	36	this	this	DT
cord-010570-ytv7dwr0	107	37	practice	practice	NN
cord-010570-ytv7dwr0	107	38	see	see	VBP
cord-010570-ytv7dwr0	107	39	[	[	-LRB-
cord-010570-ytv7dwr0	107	40	86	86	CD
cord-010570-ytv7dwr0	107	41	]	]	-RRB-
cord-010570-ytv7dwr0	108	1	[	[	-LRB-
cord-010570-ytv7dwr0	108	2	87	87	CD
cord-010570-ytv7dwr0	108	3	]	]	-RRB-
cord-010570-ytv7dwr0	109	1	[	[	-LRB-
cord-010570-ytv7dwr0	109	2	88	88	CD
cord-010570-ytv7dwr0	109	3	]	]	-RRB-
cord-010570-ytv7dwr0	109	4	[	[	-LRB-
cord-010570-ytv7dwr0	109	5	89	89	CD
cord-010570-ytv7dwr0	109	6	]	]	-RRB-
cord-010570-ytv7dwr0	109	7	)	)	-RRB-
cord-010570-ytv7dwr0	109	8	.	.	.
cord-010570-ytv7dwr0	110	1	Antibody	antibody	NN
cord-010570-ytv7dwr0	110	2	therapy	therapy	NN
cord-010570-ytv7dwr0	110	3	is	be	VBZ
cord-010570-ytv7dwr0	110	4	used	use	VBN
cord-010570-ytv7dwr0	110	5	for	for	IN
cord-010570-ytv7dwr0	110	6	a	a	DT
cord-010570-ytv7dwr0	110	7	variety	variety	NN
cord-010570-ytv7dwr0	110	8	of	of	IN
cord-010570-ytv7dwr0	110	9	illnesses	illness	NNS
cord-010570-ytv7dwr0	110	10	that	that	WDT
cord-010570-ytv7dwr0	110	11	may	may	MD
cord-010570-ytv7dwr0	110	12	or	or	CC
cord-010570-ytv7dwr0	110	13	may	may	MD
cord-010570-ytv7dwr0	110	14	not	not	RB
cord-010570-ytv7dwr0	110	15	be	be	VB
cord-010570-ytv7dwr0	110	16	infectious	infectious	JJ
cord-010570-ytv7dwr0	110	17	,	,	,
cord-010570-ytv7dwr0	110	18	including	include	VBG
cord-010570-ytv7dwr0	110	19	autoimmune	autoimmune	JJ
cord-010570-ytv7dwr0	110	20	thrombocytopenia	thrombocytopenia	NN
cord-010570-ytv7dwr0	110	21	,	,	,
cord-010570-ytv7dwr0	110	22	Kawasaki	Kawasaki	NNP
cord-010570-ytv7dwr0	110	23	disease	disease	NN
cord-010570-ytv7dwr0	110	24	,	,	,
cord-010570-ytv7dwr0	110	25	and	and	CC
cord-010570-ytv7dwr0	110	26	autoimmune	autoimmune	JJ
cord-010570-ytv7dwr0	110	27	neuromuscular	neuromuscular	JJ
cord-010570-ytv7dwr0	110	28	diseases	disease	NNS
cord-010570-ytv7dwr0	110	29	[	[	-LRB-
cord-010570-ytv7dwr0	110	30	65	65	CD
cord-010570-ytv7dwr0	110	31	,	,	,
cord-010570-ytv7dwr0	110	32	66	66	CD
cord-010570-ytv7dwr0	110	33	]	]	-RRB-
cord-010570-ytv7dwr0	110	34	.	.	.
cord-010570-ytv7dwr0	111	1	Passive	passive	JJ
cord-010570-ytv7dwr0	111	2	antibody	antibody	NNP
cord-010570-ytv7dwr0	111	3	administration	administration	NN
cord-010570-ytv7dwr0	111	4	is	be	VBZ
cord-010570-ytv7dwr0	111	5	used	use	VBN
cord-010570-ytv7dwr0	111	6	for	for	IN
cord-010570-ytv7dwr0	111	7	prevention	prevention	NN
cord-010570-ytv7dwr0	111	8	of	of	IN
cord-010570-ytv7dwr0	111	9	Rh	rh	NN
cord-010570-ytv7dwr0	111	10	-	-	HYPH
cord-010570-ytv7dwr0	111	11	hemolytic	hemolytic	JJ
cord-010570-ytv7dwr0	111	12	disease	disease	NN
cord-010570-ytv7dwr0	111	13	[	[	-LRB-
cord-010570-ytv7dwr0	111	14	90	90	CD
cord-010570-ytv7dwr0	111	15	]	]	-RRB-
cord-010570-ytv7dwr0	111	16	.	.	.
cord-010570-ytv7dwr0	112	1	Equine	equine	JJ
cord-010570-ytv7dwr0	112	2	lymphocyte	lymphocyte	NN
cord-010570-ytv7dwr0	112	3	antiserum	antiserum	NN
cord-010570-ytv7dwr0	112	4	[	[	-LRB-
cord-010570-ytv7dwr0	112	5	91	91	CD
cord-010570-ytv7dwr0	112	6	]	]	-RRB-
cord-010570-ytv7dwr0	112	7	and	and	CC
cord-010570-ytv7dwr0	112	8	murine	murine	JJ
cord-010570-ytv7dwr0	112	9	mAbs	mAbs	NNP
cord-010570-ytv7dwr0	112	10	to	to	IN
cord-010570-ytv7dwr0	112	11	lymphocytes	lymphocyte	NNS
cord-010570-ytv7dwr0	112	12	are	be	VBP
cord-010570-ytv7dwr0	112	13	used	use	VBN
cord-010570-ytv7dwr0	112	14	to	to	TO
cord-010570-ytv7dwr0	112	15	prevent	prevent	VB
cord-010570-ytv7dwr0	112	16	organ	organ	NN
cord-010570-ytv7dwr0	112	17	rejection	rejection	NN
cord-010570-ytv7dwr0	112	18	[	[	-LRB-
cord-010570-ytv7dwr0	112	19	92	92	CD
cord-010570-ytv7dwr0	112	20	]	]	-RRB-
cord-010570-ytv7dwr0	112	21	.	.	.
cord-010570-ytv7dwr0	113	1	Digitalis	digitalis	NN
cord-010570-ytv7dwr0	113	2	-	-	HYPH
cord-010570-ytv7dwr0	113	3	binding	bind	VBG
cord-010570-ytv7dwr0	113	4	antibodies	antibody	NNS
cord-010570-ytv7dwr0	113	5	are	be	VBP
cord-010570-ytv7dwr0	113	6	useful	useful	JJ
cord-010570-ytv7dwr0	113	7	for	for	IN
cord-010570-ytv7dwr0	113	8	the	the	DT
cord-010570-ytv7dwr0	113	9	treatment	treatment	NN
cord-010570-ytv7dwr0	113	10	of	of	IN
cord-010570-ytv7dwr0	113	11	digoxin	digoxin	NN
cord-010570-ytv7dwr0	113	12	toxicity	toxicity	NN
cord-010570-ytv7dwr0	113	13	[	[	-LRB-
cord-010570-ytv7dwr0	113	14	93	93	CD
cord-010570-ytv7dwr0	113	15	]	]	-RRB-
cord-010570-ytv7dwr0	113	16	.	.	.
cord-010570-ytv7dwr0	114	1	Thus	thus	RB
cord-010570-ytv7dwr0	114	2	,	,	,
cord-010570-ytv7dwr0	114	3	antibody	antibody	NN
cord-010570-ytv7dwr0	114	4	therapy	therapy	NN
cord-010570-ytv7dwr0	114	5	is	be	VBZ
cord-010570-ytv7dwr0	114	6	still	still	RB
cord-010570-ytv7dwr0	114	7	widely	widely	RB
cord-010570-ytv7dwr0	114	8	used	use	VBN
cord-010570-ytv7dwr0	114	9	in	in	IN
cord-010570-ytv7dwr0	114	10	medicine	medicine	NN
cord-010570-ytv7dwr0	114	11	,	,	,
cord-010570-ytv7dwr0	114	12	but	but	CC
cord-010570-ytv7dwr0	114	13	its	-PRON-	PRP$
cord-010570-ytv7dwr0	114	14	role	role	NN
cord-010570-ytv7dwr0	114	15	in	in	IN
cord-010570-ytv7dwr0	114	16	the	the	DT
cord-010570-ytv7dwr0	114	17	treatment	treatment	NN
cord-010570-ytv7dwr0	114	18	of	of	IN
cord-010570-ytv7dwr0	114	19	infections	infection	NNS
cord-010570-ytv7dwr0	114	20	is	be	VBZ
cord-010570-ytv7dwr0	114	21	limited	limit	VBN
cord-010570-ytv7dwr0	114	22	largely	largely	RB
cord-010570-ytv7dwr0	114	23	to	to	IN
cord-010570-ytv7dwr0	114	24	viral	viral	JJ
cord-010570-ytv7dwr0	114	25	and	and	CC
cord-010570-ytv7dwr0	114	26	toxin	toxin	NN
cord-010570-ytv7dwr0	114	27	neutralization	neutralization	NN
cord-010570-ytv7dwr0	114	28	and	and	CC
cord-010570-ytv7dwr0	114	29	replacement	replacement	NN
cord-010570-ytv7dwr0	114	30	therapy	therapy	NN
cord-010570-ytv7dwr0	114	31	in	in	IN
cord-010570-ytv7dwr0	114	32	patients	patient	NNS
cord-010570-ytv7dwr0	114	33	with	with	IN
cord-010570-ytv7dwr0	114	34	immunoglobulin	immunoglobulin	NN
cord-010570-ytv7dwr0	114	35	deficiencies	deficiency	NNS
cord-010570-ytv7dwr0	114	36	.	.	.
cord-010570-ytv7dwr0	115	1	In	in	IN
cord-010570-ytv7dwr0	115	2	reconsidering	reconsider	VBG
cord-010570-ytv7dwr0	115	3	the	the	DT
cord-010570-ytv7dwr0	115	4	antibody	antibody	NN
cord-010570-ytv7dwr0	115	5	option	option	NN
cord-010570-ytv7dwr0	115	6	it	-PRON-	PRP
cord-010570-ytv7dwr0	115	7	is	be	VBZ
cord-010570-ytv7dwr0	115	8	clear	clear	JJ
cord-010570-ytv7dwr0	115	9	that	that	IN
cord-010570-ytv7dwr0	115	10	heterologous	heterologous	JJ
cord-010570-ytv7dwr0	115	11	antibody	antibody	NN
cord-010570-ytv7dwr0	115	12	(	(	-LRB-
cord-010570-ytv7dwr0	115	13	i.e.	i.e.	FW
cord-010570-ytv7dwr0	115	14	,	,	,
cord-010570-ytv7dwr0	115	15	serum	serum	NN
cord-010570-ytv7dwr0	115	16	therapy	therapy	NN
cord-010570-ytv7dwr0	115	17	)	)	-RRB-
cord-010570-ytv7dwr0	115	18	is	be	VBZ
cord-010570-ytv7dwr0	115	19	a	a	DT
cord-010570-ytv7dwr0	115	20	poor	poor	JJ
cord-010570-ytv7dwr0	115	21	choice	choice	NN
cord-010570-ytv7dwr0	115	22	because	because	IN
cord-010570-ytv7dwr0	115	23	of	of	IN
cord-010570-ytv7dwr0	115	24	toxicity	toxicity	NN
cord-010570-ytv7dwr0	115	25	.	.	.
cord-010570-ytv7dwr0	116	1	Human	human	JJ
cord-010570-ytv7dwr0	116	2	immune	immune	NN
cord-010570-ytv7dwr0	116	3	sera	sera	NNP
cord-010570-ytv7dwr0	116	4	have	have	VBP
cord-010570-ytv7dwr0	116	5	fewer	few	JJR
cord-010570-ytv7dwr0	116	6	side	side	NN
cord-010570-ytv7dwr0	116	7	effects	effect	NNS
cord-010570-ytv7dwr0	116	8	,	,	,
cord-010570-ytv7dwr0	116	9	but	but	CC
cord-010570-ytv7dwr0	116	10	there	there	EX
cord-010570-ytv7dwr0	116	11	are	be	VBP
cord-010570-ytv7dwr0	116	12	concerns	concern	NNS
cord-010570-ytv7dwr0	116	13	about	about	IN
cord-010570-ytv7dwr0	116	14	availability	availability	NN
cord-010570-ytv7dwr0	116	15	,	,	,
cord-010570-ytv7dwr0	116	16	potency	potency	NN
cord-010570-ytv7dwr0	116	17	,	,	,
cord-010570-ytv7dwr0	116	18	and	and	CC
cord-010570-ytv7dwr0	116	19	consistency	consistency	NN
cord-010570-ytv7dwr0	116	20	.	.	.
cord-010570-ytv7dwr0	117	1	A	a	DT
cord-010570-ytv7dwr0	117	2	major	major	JJ
cord-010570-ytv7dwr0	117	3	disadvantage	disadvantage	NN
cord-010570-ytv7dwr0	117	4	of	of	IN
cord-010570-ytv7dwr0	117	5	all	all	DT
cord-010570-ytv7dwr0	117	6	immune	immune	JJ
cord-010570-ytv7dwr0	117	7	sera	sera	NNP
cord-010570-ytv7dwr0	117	8	is	be	VBZ
cord-010570-ytv7dwr0	117	9	that	that	DT
cord-010570-ytv7dwr0	117	10	specific	specific	JJ
cord-010570-ytv7dwr0	117	11	antibodies	antibody	NNS
cord-010570-ytv7dwr0	117	12	make	make	VBP
cord-010570-ytv7dwr0	117	13	up	up	RP
cord-010570-ytv7dwr0	117	14	a	a	DT
cord-010570-ytv7dwr0	117	15	small	small	JJ
cord-010570-ytv7dwr0	117	16	minority	minority	NN
cord-010570-ytv7dwr0	117	17	of	of	IN
cord-010570-ytv7dwr0	117	18	the	the	DT
cord-010570-ytv7dwr0	117	19	antibody	antibody	NN
cord-010570-ytv7dwr0	117	20	present	present	NN
cord-010570-ytv7dwr0	117	21	.	.	.
cord-010570-ytv7dwr0	118	1	There	there	EX
cord-010570-ytv7dwr0	118	2	is	be	VBZ
cord-010570-ytv7dwr0	118	3	significant	significant	JJ
cord-010570-ytv7dwr0	118	4	variation	variation	NN
cord-010570-ytv7dwr0	118	5	in	in	IN
cord-010570-ytv7dwr0	118	6	pathogen	pathogen	NN
cord-010570-ytv7dwr0	118	7	-	-	HYPH
cord-010570-ytv7dwr0	118	8	specific	specific	JJ
cord-010570-ytv7dwr0	118	9	opsonic	opsonic	JJ
cord-010570-ytv7dwr0	118	10	activity	activity	NN
cord-010570-ytv7dwr0	118	11	of	of	IN
cord-010570-ytv7dwr0	118	12	commercially	commercially	RB
cord-010570-ytv7dwr0	118	13	available	available	JJ
cord-010570-ytv7dwr0	118	14	immunoglobulin	immunoglobulin	NN
cord-010570-ytv7dwr0	118	15	preparations	preparation	NNS
cord-010570-ytv7dwr0	118	16	[	[	-LRB-
cord-010570-ytv7dwr0	118	17	94	94	CD
cord-010570-ytv7dwr0	118	18	]	]	-RRB-
cord-010570-ytv7dwr0	118	19	.	.	.
cord-010570-ytv7dwr0	119	1	There	there	EX
cord-010570-ytv7dwr0	119	2	is	be	VBZ
cord-010570-ytv7dwr0	119	3	also	also	RB
cord-010570-ytv7dwr0	119	4	concern	concern	NN
cord-010570-ytv7dwr0	119	5	about	about	IN
cord-010570-ytv7dwr0	119	6	the	the	DT
cord-010570-ytv7dwr0	119	7	potential	potential	NN
cord-010570-ytv7dwr0	119	8	of	of	IN
cord-010570-ytv7dwr0	119	9	human	human	JJ
cord-010570-ytv7dwr0	119	10	sera	sera	NNP
cord-010570-ytv7dwr0	119	11	to	to	TO
cord-010570-ytv7dwr0	119	12	transmit	transmit	VB
cord-010570-ytv7dwr0	119	13	infectious	infectious	JJ
cord-010570-ytv7dwr0	119	14	agents	agent	NNS
cord-010570-ytv7dwr0	119	15	[	[	-LRB-
cord-010570-ytv7dwr0	119	16	95	95	CD
cord-010570-ytv7dwr0	119	17	]	]	-RRB-
cord-010570-ytv7dwr0	119	18	.	.	.
cord-010570-ytv7dwr0	120	1	The	the	DT
cord-010570-ytv7dwr0	120	2	discovery	discovery	NN
cord-010570-ytv7dwr0	120	3	of	of	IN
cord-010570-ytv7dwr0	120	4	hybridoma	hybridoma	NN
cord-010570-ytv7dwr0	120	5	technology	technology	NN
cord-010570-ytv7dwr0	120	6	in	in	IN
cord-010570-ytv7dwr0	120	7	1975	1975	CD
cord-010570-ytv7dwr0	120	8	[	[	-LRB-
cord-010570-ytv7dwr0	120	9	96	96	CD
cord-010570-ytv7dwr0	120	10	]	]	-RRB-
cord-010570-ytv7dwr0	120	11	and	and	CC
cord-010570-ytv7dwr0	120	12	recent	recent	JJ
cord-010570-ytv7dwr0	120	13	advances	advance	NNS
cord-010570-ytv7dwr0	120	14	in	in	IN
cord-010570-ytv7dwr0	120	15	mAb	mab	NN
cord-010570-ytv7dwr0	120	16	technology	technology	NN
cord-010570-ytv7dwr0	120	17	,	,	,
cord-010570-ytv7dwr0	120	18	including	include	VBG
cord-010570-ytv7dwr0	120	19	the	the	DT
cord-010570-ytv7dwr0	120	20	generation	generation	NN
cord-010570-ytv7dwr0	120	21	of	of	IN
cord-010570-ytv7dwr0	120	22	humanized	humanized	JJ
cord-010570-ytv7dwr0	120	23	antibodies	antibody	NNS
cord-010570-ytv7dwr0	120	24	[	[	-LRB-
cord-010570-ytv7dwr0	120	25	97	97	CD
cord-010570-ytv7dwr0	120	26	]	]	-RRB-
cord-010570-ytv7dwr0	120	27	,	,	,
cord-010570-ytv7dwr0	120	28	make	make	VBP
cord-010570-ytv7dwr0	120	29	mAb	mab	NN
cord-010570-ytv7dwr0	120	30	-	-	HYPH
cord-010570-ytv7dwr0	120	31	based	base	VBN
cord-010570-ytv7dwr0	120	32	therapies	therapy	NNS
cord-010570-ytv7dwr0	120	33	a	a	DT
cord-010570-ytv7dwr0	120	34	more	more	RBR
cord-010570-ytv7dwr0	120	35	attractive	attractive	JJ
cord-010570-ytv7dwr0	120	36	therapeutic	therapeutic	JJ
cord-010570-ytv7dwr0	120	37	option	option	NN
cord-010570-ytv7dwr0	120	38	.	.	.
cord-010570-ytv7dwr0	121	1	In	in	IN
cord-010570-ytv7dwr0	121	2	contrast	contrast	NN
cord-010570-ytv7dwr0	121	3	to	to	IN
cord-010570-ytv7dwr0	121	4	polyclonal	polyclonal	JJ
cord-010570-ytv7dwr0	121	5	sera	sera	NNP
cord-010570-ytv7dwr0	121	6	,	,	,
cord-010570-ytv7dwr0	121	7	mAbs	mAbs	NNP
cord-010570-ytv7dwr0	121	8	are	be	VBP
cord-010570-ytv7dwr0	121	9	homogeneous	homogeneous	JJ
cord-010570-ytv7dwr0	121	10	and	and	CC
cord-010570-ytv7dwr0	121	11	reproducible	reproducible	JJ
cord-010570-ytv7dwr0	121	12	reagents	reagent	NNS
cord-010570-ytv7dwr0	121	13	that	that	WDT
cord-010570-ytv7dwr0	121	14	can	can	MD
cord-010570-ytv7dwr0	121	15	be	be	VB
cord-010570-ytv7dwr0	121	16	generated	generate	VBN
cord-010570-ytv7dwr0	121	17	in	in	IN
cord-010570-ytv7dwr0	121	18	large	large	JJ
cord-010570-ytv7dwr0	121	19	amounts	amount	NNS
cord-010570-ytv7dwr0	121	20	.	.	.
cord-010570-ytv7dwr0	122	1	Generation	generation	NN
cord-010570-ytv7dwr0	122	2	of	of	IN
cord-010570-ytv7dwr0	122	3	mAbs	mabs	NN
cord-010570-ytv7dwr0	122	4	from	from	IN
cord-010570-ytv7dwr0	122	5	mice	mouse	NNS
cord-010570-ytv7dwr0	122	6	and	and	CC
cord-010570-ytv7dwr0	122	7	rats	rat	NNS
cord-010570-ytv7dwr0	122	8	is	be	VBZ
cord-010570-ytv7dwr0	122	9	still	still	RB
cord-010570-ytv7dwr0	122	10	easier	easy	JJR
cord-010570-ytv7dwr0	122	11	and	and	CC
cord-010570-ytv7dwr0	122	12	more	more	RBR
cord-010570-ytv7dwr0	122	13	efficient	efficient	JJ
cord-010570-ytv7dwr0	122	14	than	than	IN
cord-010570-ytv7dwr0	122	15	production	production	NN
cord-010570-ytv7dwr0	122	16	of	of	IN
cord-010570-ytv7dwr0	122	17	human	human	JJ
cord-010570-ytv7dwr0	122	18	mAbs	mAbs	NNP
cord-010570-ytv7dwr0	122	19	.	.	.
cord-010570-ytv7dwr0	123	1	However	however	RB
cord-010570-ytv7dwr0	123	2	,	,	,
cord-010570-ytv7dwr0	123	3	several	several	JJ
cord-010570-ytv7dwr0	123	4	technologies	technology	NNS
cord-010570-ytv7dwr0	123	5	are	be	VBP
cord-010570-ytv7dwr0	123	6	available	available	JJ
cord-010570-ytv7dwr0	123	7	for	for	IN
cord-010570-ytv7dwr0	123	8	the	the	DT
cord-010570-ytv7dwr0	123	9	humanization	humanization	NN
cord-010570-ytv7dwr0	123	10	of	of	IN
cord-010570-ytv7dwr0	123	11	murine	murine	NNP
cord-010570-ytv7dwr0	123	12	mAbs	mAbs	NNP
cord-010570-ytv7dwr0	123	13	and	and	CC
cord-010570-ytv7dwr0	123	14	generation	generation	NN
cord-010570-ytv7dwr0	123	15	of	of	IN
cord-010570-ytv7dwr0	123	16	human	human	JJ
cord-010570-ytv7dwr0	123	17	mAbs	mAbs	NNP
cord-010570-ytv7dwr0	123	18	[	[	-LRB-
cord-010570-ytv7dwr0	123	19	97	97	CD
cord-010570-ytv7dwr0	123	20	]	]	-RRB-
cord-010570-ytv7dwr0	123	21	.	.	.
cord-010570-ytv7dwr0	124	1	Mouse	mouse	NN
cord-010570-ytv7dwr0	124	2	-	-	HYPH
cord-010570-ytv7dwr0	124	3	human	human	JJ
cord-010570-ytv7dwr0	124	4	chimeric	chimeric	JJ
cord-010570-ytv7dwr0	124	5	antibodies	antibody	NNS
cord-010570-ytv7dwr0	124	6	can	can	MD
cord-010570-ytv7dwr0	124	7	be	be	VB
cord-010570-ytv7dwr0	124	8	constructed	construct	VBN
cord-010570-ytv7dwr0	124	9	by	by	IN
cord-010570-ytv7dwr0	124	10	linking	link	VBG
cord-010570-ytv7dwr0	124	11	the	the	DT
cord-010570-ytv7dwr0	124	12	genes	gene	NNS
cord-010570-ytv7dwr0	124	13	expressing	express	VBG
cord-010570-ytv7dwr0	124	14	the	the	DT
cord-010570-ytv7dwr0	124	15	mouse	mouse	NN
cord-010570-ytv7dwr0	124	16	variable	variable	JJ
cord-010570-ytv7dwr0	124	17	region	region	NN
cord-010570-ytv7dwr0	124	18	to	to	IN
cord-010570-ytv7dwr0	124	19	human	human	JJ
cord-010570-ytv7dwr0	124	20	constant	constant	JJ
cord-010570-ytv7dwr0	124	21	region	region	NN
cord-010570-ytv7dwr0	124	22	genes	gene	NNS
cord-010570-ytv7dwr0	124	23	[	[	-LRB-
cord-010570-ytv7dwr0	124	24	97	97	CD
cord-010570-ytv7dwr0	124	25	]	]	-RRB-
cord-010570-ytv7dwr0	124	26	.	.	.
cord-010570-ytv7dwr0	125	1	The	the	DT
cord-010570-ytv7dwr0	125	2	result	result	NN
cord-010570-ytv7dwr0	125	3	is	be	VBZ
cord-010570-ytv7dwr0	125	4	a	a	DT
cord-010570-ytv7dwr0	125	5	molecule	molecule	NN
cord-010570-ytv7dwr0	125	6	that	that	WDT
cord-010570-ytv7dwr0	125	7	is	be	VBZ
cord-010570-ytv7dwr0	125	8	mostly	mostly	RB
cord-010570-ytv7dwr0	125	9	human	human	JJ
cord-010570-ytv7dwr0	125	10	and	and	CC
cord-010570-ytv7dwr0	125	11	has	have	VBZ
cord-010570-ytv7dwr0	125	12	a	a	DT
cord-010570-ytv7dwr0	125	13	longer	long	JJR
cord-010570-ytv7dwr0	125	14	half	half	JJ
cord-010570-ytv7dwr0	125	15	-	-	HYPH
cord-010570-ytv7dwr0	125	16	life	life	NN
cord-010570-ytv7dwr0	125	17	than	than	IN
cord-010570-ytv7dwr0	125	18	the	the	DT
cord-010570-ytv7dwr0	125	19	murine	murine	JJ
cord-010570-ytv7dwr0	125	20	precursor	precursor	NN
cord-010570-ytv7dwr0	125	21	[	[	-LRB-
cord-010570-ytv7dwr0	125	22	98	98	CD
cord-010570-ytv7dwr0	125	23	]	]	-RRB-
cord-010570-ytv7dwr0	125	24	.	.	.
cord-010570-ytv7dwr0	126	1	As	as	IN
cord-010570-ytv7dwr0	126	2	an	an	DT
cord-010570-ytv7dwr0	126	3	alternative	alternative	NN
cord-010570-ytv7dwr0	126	4	,	,	,
cord-010570-ytv7dwr0	126	5	the	the	DT
cord-010570-ytv7dwr0	126	6	antigen	antigen	NN
cord-010570-ytv7dwr0	126	7	binding	bind	VBG
cord-010570-ytv7dwr0	126	8	regions	region	NNS
cord-010570-ytv7dwr0	126	9	of	of	IN
cord-010570-ytv7dwr0	126	10	murine	murine	JJ
cord-010570-ytv7dwr0	126	11	mAbs	mAbs	NNP
cord-010570-ytv7dwr0	126	12	can	can	MD
cord-010570-ytv7dwr0	126	13	be	be	VB
cord-010570-ytv7dwr0	126	14	grafted	graft	VBN
cord-010570-ytv7dwr0	126	15	into	into	IN
cord-010570-ytv7dwr0	126	16	human	human	JJ
cord-010570-ytv7dwr0	126	17	antibody	antibody	NN
cord-010570-ytv7dwr0	126	18	frameworks	framework	NNS
cord-010570-ytv7dwr0	126	19	by	by	IN
cord-010570-ytv7dwr0	126	20	molecular	molecular	JJ
cord-010570-ytv7dwr0	126	21	techniques	technique	NNS
cord-010570-ytv7dwr0	126	22	[	[	-LRB-
cord-010570-ytv7dwr0	126	23	97	97	CD
cord-010570-ytv7dwr0	126	24	]	]	-RRB-
cord-010570-ytv7dwr0	126	25	,	,	,
cord-010570-ytv7dwr0	126	26	resulting	result	VBG
cord-010570-ytv7dwr0	126	27	in	in	IN
cord-010570-ytv7dwr0	126	28	molecules	molecule	NNS
cord-010570-ytv7dwr0	126	29	that	that	WDT
cord-010570-ytv7dwr0	126	30	are	be	VBP
cord-010570-ytv7dwr0	126	31	almost	almost	RB
cord-010570-ytv7dwr0	126	32	completely	completely	RB
cord-010570-ytv7dwr0	126	33	human	human	JJ
cord-010570-ytv7dwr0	126	34	in	in	IN
cord-010570-ytv7dwr0	126	35	origin	origin	NN
cord-010570-ytv7dwr0	126	36	.	.	.
cord-010570-ytv7dwr0	127	1	Other	other	JJ
cord-010570-ytv7dwr0	127	2	strategies	strategy	NNS
cord-010570-ytv7dwr0	127	3	to	to	TO
cord-010570-ytv7dwr0	127	4	generate	generate	VB
cord-010570-ytv7dwr0	127	5	human	human	JJ
cord-010570-ytv7dwr0	127	6	antibodies	antibody	NNS
cord-010570-ytv7dwr0	127	7	are	be	VBP
cord-010570-ytv7dwr0	127	8	the	the	DT
cord-010570-ytv7dwr0	127	9	transformation	transformation	NN
cord-010570-ytv7dwr0	127	10	of	of	IN
cord-010570-ytv7dwr0	127	11	human	human	JJ
cord-010570-ytv7dwr0	127	12	B	b	NN
cord-010570-ytv7dwr0	127	13	cells	cell	NNS
cord-010570-ytv7dwr0	127	14	,	,	,
cord-010570-ytv7dwr0	127	15	the	the	DT
cord-010570-ytv7dwr0	127	16	generation	generation	NN
cord-010570-ytv7dwr0	127	17	ofrecombinant	ofrecombinant	JJ
cord-010570-ytv7dwr0	127	18	antibody	antibody	NN
cord-010570-ytv7dwr0	127	19	libraries	library	NNS
cord-010570-ytv7dwr0	127	20	from	from	IN
cord-010570-ytv7dwr0	127	21	human	human	JJ
cord-010570-ytv7dwr0	127	22	B	b	NN
cord-010570-ytv7dwr0	127	23	cells	cell	NNS
cord-010570-ytv7dwr0	127	24	,	,	,
cord-010570-ytv7dwr0	127	25	and	and	CC
cord-010570-ytv7dwr0	127	26	the	the	DT
cord-010570-ytv7dwr0	127	27	use	use	NN
cord-010570-ytv7dwr0	127	28	of	of	IN
cord-010570-ytv7dwr0	127	29	transgenic	transgenic	JJ
cord-010570-ytv7dwr0	127	30	mice	mouse	NNS
cord-010570-ytv7dwr0	127	31	that	that	WDT
cord-010570-ytv7dwr0	127	32	have	have	VBP
cord-010570-ytv7dwr0	127	33	the	the	DT
cord-010570-ytv7dwr0	127	34	human	human	JJ
cord-010570-ytv7dwr0	127	35	immunoglobulin	immunoglobulin	NN
cord-010570-ytv7dwr0	127	36	locus	locus	NN
cord-010570-ytv7dwr0	127	37	.	.	.
cord-010570-ytv7dwr0	128	1	Recent	recent	JJ
cord-010570-ytv7dwr0	128	2	Setbacks	setback	NNS
cord-010570-ytv7dwr0	128	3	for	for	IN
cord-010570-ytv7dwr0	128	4	mAb	mab	NN
cord-010570-ytv7dwr0	128	5	-	-	HYPH
cord-010570-ytv7dwr0	128	6	Based	base	VBN
cord-010570-ytv7dwr0	128	7	Therapies	Therapies	NNPS
cord-010570-ytv7dwr0	128	8	:	:	:
cord-010570-ytv7dwr0	128	9	Historical	Historical	NNP
cord-010570-ytv7dwr0	128	10	Perspective	Perspective	NNP
cord-010570-ytv7dwr0	128	11	Clinical	clinical	JJ
cord-010570-ytv7dwr0	128	12	trials	trial	NNS
cord-010570-ytv7dwr0	128	13	of	of	IN
cord-010570-ytv7dwr0	128	14	antiendotoxin	antiendotoxin	NNP
cord-010570-ytv7dwr0	128	15	mAbs	mAbs	NNP
cord-010570-ytv7dwr0	128	16	for	for	IN
cord-010570-ytv7dwr0	128	17	gram	gram	NN
cord-010570-ytv7dwr0	128	18	-	-	HYPH
cord-010570-ytv7dwr0	128	19	negative	negative	JJ
cord-010570-ytv7dwr0	128	20	sepsis	sepsis	NN
cord-010570-ytv7dwr0	128	21	have	have	VBP
cord-010570-ytv7dwr0	128	22	produced	produce	VBN
cord-010570-ytv7dwr0	128	23	inconclusive	inconclusive	JJ
cord-010570-ytv7dwr0	128	24	results	result	NNS
cord-010570-ytv7dwr0	128	25	[	[	-LRB-
cord-010570-ytv7dwr0	128	26	99	99	CD
cord-010570-ytv7dwr0	128	27	,	,	,
cord-010570-ytv7dwr0	128	28	100	100	CD
cord-010570-ytv7dwr0	128	29	]	]	-RRB-
cord-010570-ytv7dwr0	128	30	.	.	.
cord-010570-ytv7dwr0	129	1	When	when	WRB
cord-010570-ytv7dwr0	129	2	the	the	DT
cord-010570-ytv7dwr0	129	3	difficulties	difficulty	NNS
cord-010570-ytv7dwr0	129	4	encountered	encounter	VBN
cord-010570-ytv7dwr0	129	5	in	in	IN
cord-010570-ytv7dwr0	129	6	developing	develop	VBG
cord-010570-ytv7dwr0	129	7	antiendotoxin	antiendotoxin	NN
cord-010570-ytv7dwr0	129	8	mAb	mab	NN
cord-010570-ytv7dwr0	129	9	strategies	strategy	NNS
cord-010570-ytv7dwr0	129	10	are	be	VBP
cord-010570-ytv7dwr0	129	11	considered	consider	VBN
cord-010570-ytv7dwr0	129	12	in	in	IN
cord-010570-ytv7dwr0	129	13	the	the	DT
cord-010570-ytv7dwr0	129	14	context	context	NN
cord-010570-ytv7dwr0	129	15	of	of	IN
cord-010570-ytv7dwr0	129	16	the	the	DT
cord-010570-ytv7dwr0	129	17	development	development	NN
cord-010570-ytv7dwr0	129	18	of	of	IN
cord-010570-ytv7dwr0	129	19	serum	serum	NN
cord-010570-ytv7dwr0	129	20	therapy	therapy	NN
cord-010570-ytv7dwr0	129	21	,	,	,
cord-010570-ytv7dwr0	129	22	they	-PRON-	PRP
cord-010570-ytv7dwr0	129	23	do	do	VBP
cord-010570-ytv7dwr0	129	24	not	not	RB
cord-010570-ytv7dwr0	129	25	seem	seem	VB
cord-010570-ytv7dwr0	129	26	unusual	unusual	JJ
cord-010570-ytv7dwr0	129	27	or	or	CC
cord-010570-ytv7dwr0	129	28	unexpected	unexpected	JJ
cord-010570-ytv7dwr0	129	29	.	.	.
cord-010570-ytv7dwr0	130	1	For	for	IN
cord-010570-ytv7dwr0	130	2	example	example	NN
cord-010570-ytv7dwr0	130	3	,	,	,
cord-010570-ytv7dwr0	130	4	passive	passive	JJ
cord-010570-ytv7dwr0	130	5	protection	protection	NN
cord-010570-ytv7dwr0	130	6	with	with	IN
cord-010570-ytv7dwr0	130	7	pneumococcal	pneumococcal	JJ
cord-010570-ytv7dwr0	130	8	antisera	antisera	NN
cord-010570-ytv7dwr0	130	9	was	be	VBD
cord-010570-ytv7dwr0	130	10	demonstrated	demonstrate	VBN
cord-010570-ytv7dwr0	130	11	in	in	IN
cord-010570-ytv7dwr0	130	12	1891	1891	CD
cord-010570-ytv7dwr0	130	13	by	by	IN
cord-010570-ytv7dwr0	130	14	the	the	DT
cord-010570-ytv7dwr0	130	15	Klemperers	Klemperers	NNPS
cord-010570-ytv7dwr0	130	16	[	[	-LRB-
cord-010570-ytv7dwr0	130	17	101	101	CD
cord-010570-ytv7dwr0	130	18	]	]	-RRB-
cord-010570-ytv7dwr0	130	19	,	,	,
cord-010570-ytv7dwr0	130	20	but	but	CC
cord-010570-ytv7dwr0	130	21	30	30	CD
cord-010570-ytv7dwr0	130	22	-	-	SYM
cord-010570-ytv7dwr0	130	23	40	40	CD
cord-010570-ytv7dwr0	130	24	years	year	NNS
cord-010570-ytv7dwr0	130	25	elapsed	elapse	VBN
cord-010570-ytv7dwr0	130	26	before	before	IN
cord-010570-ytv7dwr0	130	27	serum	serum	NN
cord-010570-ytv7dwr0	130	28	therapy	therapy	NN
cord-010570-ytv7dwr0	130	29	for	for	IN
cord-010570-ytv7dwr0	130	30	pneumococcal	pneumococcal	JJ
cord-010570-ytv7dwr0	130	31	pneumonia	pneumonia	NN
cord-010570-ytv7dwr0	130	32	was	be	VBD
cord-010570-ytv7dwr0	130	33	widely	widely	RB
cord-010570-ytv7dwr0	130	34	accepted	accept	VBN
cord-010570-ytv7dwr0	130	35	.	.	.
cord-010570-ytv7dwr0	131	1	For	for	IN
cord-010570-ytv7dwr0	131	2	pneumococcal	pneumococcal	JJ
cord-010570-ytv7dwr0	131	3	antiserum	antiserum	NN
cord-010570-ytv7dwr0	131	4	therapy	therapy	NN
cord-010570-ytv7dwr0	131	5	to	to	TO
cord-010570-ytv7dwr0	131	6	be	be	VB
cord-010570-ytv7dwr0	131	7	consistently	consistently	RB
cord-010570-ytv7dwr0	131	8	successful	successful	JJ
cord-010570-ytv7dwr0	131	9	,	,	,
cord-010570-ytv7dwr0	131	10	several	several	JJ
cord-010570-ytv7dwr0	131	11	developments	development	NNS
cord-010570-ytv7dwr0	131	12	were	be	VBD
cord-010570-ytv7dwr0	131	13	necessary	necessary	JJ
cord-010570-ytv7dwr0	131	14	.	.	.
cord-010570-ytv7dwr0	132	1	These	these	DT
cord-010570-ytv7dwr0	132	2	included	include	VBD
cord-010570-ytv7dwr0	132	3	the	the	DT
cord-010570-ytv7dwr0	132	4	appreciation	appreciation	NN
cord-010570-ytv7dwr0	132	5	of	of	IN
cord-010570-ytv7dwr0	132	6	antigenic	antigenic	JJ
cord-010570-ytv7dwr0	132	7	variation	variation	NN
cord-010570-ytv7dwr0	132	8	in	in	IN
cord-010570-ytv7dwr0	132	9	pneumococci	pneumococci	NNP
cord-010570-ytv7dwr0	132	10	[	[	-LRB-
cord-010570-ytv7dwr0	132	11	102	102	CD
cord-010570-ytv7dwr0	132	12	]	]	-RRB-
cord-010570-ytv7dwr0	132	13	,	,	,
cord-010570-ytv7dwr0	132	14	the	the	DT
cord-010570-ytv7dwr0	132	15	need	need	NN
cord-010570-ytv7dwr0	132	16	for	for	IN
cord-010570-ytv7dwr0	132	17	type	type	NN
cord-010570-ytv7dwr0	132	18	-	-	HYPH
cord-010570-ytv7dwr0	132	19	specific	specific	JJ
cord-010570-ytv7dwr0	132	20	sera	sera	FW
cord-010570-ytv7dwr0	132	21	[	[	-LRB-
cord-010570-ytv7dwr0	132	22	103	103	CD
cord-010570-ytv7dwr0	132	23	]	]	-RRB-
cord-010570-ytv7dwr0	132	24	,	,	,
cord-010570-ytv7dwr0	132	25	the	the	DT
cord-010570-ytv7dwr0	132	26	development	development	NN
cord-010570-ytv7dwr0	132	27	of	of	IN
cord-010570-ytv7dwr0	132	28	rapid	rapid	JJ
cord-010570-ytv7dwr0	132	29	in	in	IN
cord-010570-ytv7dwr0	132	30	vitro	vitro	FW
cord-010570-ytv7dwr0	132	31	assays	assay	NNS
cord-010570-ytv7dwr0	132	32	to	to	TO
cord-010570-ytv7dwr0	132	33	establish	establish	VB
cord-010570-ytv7dwr0	132	34	antigenic	antigenic	JJ
cord-010570-ytv7dwr0	132	35	type	type	NN
cord-010570-ytv7dwr0	132	36	(	(	-LRB-
cord-010570-ytv7dwr0	132	37	i.e.	i.e.	FW
cord-010570-ytv7dwr0	132	38	,	,	,
cord-010570-ytv7dwr0	132	39	capsular	capsular	JJ
cord-010570-ytv7dwr0	132	40	swelling	swelling	NN
cord-010570-ytv7dwr0	132	41	and	and	CC
cord-010570-ytv7dwr0	132	42	agglutination	agglutination	NN
cord-010570-ytv7dwr0	132	43	reactions	reaction	NNS
cord-010570-ytv7dwr0	132	44	)	)	-RRB-
cord-010570-ytv7dwr0	132	45	[	[	-LRB-
cord-010570-ytv7dwr0	132	46	104	104	CD
cord-010570-ytv7dwr0	132	47	]	]	-RRB-
cord-010570-ytv7dwr0	132	48	,	,	,
cord-010570-ytv7dwr0	132	49	the	the	DT
cord-010570-ytv7dwr0	132	50	development	development	NN
cord-010570-ytv7dwr0	132	51	of	of	IN
cord-010570-ytv7dwr0	132	52	methods	method	NNS
cord-010570-ytv7dwr0	132	53	to	to	TO
cord-010570-ytv7dwr0	132	54	standardize	standardize	VB
cord-010570-ytv7dwr0	132	55	potency	potency	NN
cord-010570-ytv7dwr0	132	56	(	(	-LRB-
cord-010570-ytv7dwr0	132	57	mouse	mouse	NN
cord-010570-ytv7dwr0	132	58	protection	protection	NN
cord-010570-ytv7dwr0	132	59	test	test	NN
cord-010570-ytv7dwr0	132	60	)	)	-RRB-
cord-010570-ytv7dwr0	132	61	[	[	-LRB-
cord-010570-ytv7dwr0	132	62	46	46	CD
cord-010570-ytv7dwr0	132	63	]	]	-RRB-
cord-010570-ytv7dwr0	132	64	,	,	,
cord-010570-ytv7dwr0	132	65	and	and	CC
cord-010570-ytv7dwr0	132	66	improved	improve	VBN
cord-010570-ytv7dwr0	132	67	purification	purification	NN
cord-010570-ytv7dwr0	132	68	techniques	technique	NNS
cord-010570-ytv7dwr0	132	69	that	that	WDT
cord-010570-ytv7dwr0	132	70	would	would	MD
cord-010570-ytv7dwr0	132	71	reduce	reduce	VB
cord-010570-ytv7dwr0	132	72	the	the	DT
cord-010570-ytv7dwr0	132	73	toxicity	toxicity	NN
cord-010570-ytv7dwr0	132	74	of	of	IN
cord-010570-ytv7dwr0	132	75	serum	serum	NN
cord-010570-ytv7dwr0	132	76	.	.	.
cord-010570-ytv7dwr0	133	1	For	for	IN
cord-010570-ytv7dwr0	133	2	meningococcal	meningococcal	JJ
cord-010570-ytv7dwr0	133	3	antisera	antisera	NN
cord-010570-ytv7dwr0	133	4	the	the	DT
cord-010570-ytv7dwr0	133	5	situation	situation	NN
cord-010570-ytv7dwr0	133	6	was	be	VBD
cord-010570-ytv7dwr0	133	7	reversed	reverse	VBN
cord-010570-ytv7dwr0	133	8	;	;	:
cord-010570-ytv7dwr0	133	9	Flexner	Flexner	NNP
cord-010570-ytv7dwr0	133	10	's	's	POS
cord-010570-ytv7dwr0	133	11	serum	serum	NN
cord-010570-ytv7dwr0	133	12	significantly	significantly	RB
cord-010570-ytv7dwr0	133	13	reduced	reduce	VBN
cord-010570-ytv7dwr0	133	14	mortality	mortality	NN
cord-010570-ytv7dwr0	133	15	in	in	IN
cord-010570-ytv7dwr0	133	16	early	early	JJ
cord-010570-ytv7dwr0	133	17	epidemics	epidemic	NNS
cord-010570-ytv7dwr0	133	18	of	of	IN
cord-010570-ytv7dwr0	133	19	meningitis	meningitis	NN
cord-010570-ytv7dwr0	133	20	[	[	-LRB-
cord-010570-ytv7dwr0	133	21	38	38	CD
cord-010570-ytv7dwr0	133	22	]	]	-RRB-
cord-010570-ytv7dwr0	133	23	but	but	CC
cord-010570-ytv7dwr0	133	24	was	be	VBD
cord-010570-ytv7dwr0	133	25	subsequently	subsequently	RB
cord-010570-ytv7dwr0	133	26	less	less	RBR
cord-010570-ytv7dwr0	133	27	effective	effective	JJ
cord-010570-ytv7dwr0	133	28	,	,	,
cord-010570-ytv7dwr0	133	29	possibly	possibly	RB
cord-010570-ytv7dwr0	133	30	as	as	IN
cord-010570-ytv7dwr0	133	31	a	a	DT
cord-010570-ytv7dwr0	133	32	result	result	NN
cord-010570-ytv7dwr0	133	33	of	of	IN
cord-010570-ytv7dwr0	133	34	antigenic	antigenic	JJ
cord-010570-ytv7dwr0	133	35	changes	change	NNS
cord-010570-ytv7dwr0	133	36	in	in	IN
cord-010570-ytv7dwr0	133	37	Neisseria	Neisseria	NNP
cord-010570-ytv7dwr0	133	38	meningitidis	meningitidis	NNP
cord-010570-ytv7dwr0	133	39	[	[	-LRB-
cord-010570-ytv7dwr0	133	40	7	7	CD
cord-010570-ytv7dwr0	133	41	]	]	-RRB-
cord-010570-ytv7dwr0	133	42	.	.	.
cord-010570-ytv7dwr0	134	1	Research	research	NN
cord-010570-ytv7dwr0	134	2	into	into	IN
cord-010570-ytv7dwr0	134	3	better	well	JJR
cord-010570-ytv7dwr0	134	4	meningococcal	meningococcal	JJ
cord-010570-ytv7dwr0	134	5	antisera	antisera	NN
cord-010570-ytv7dwr0	134	6	was	be	VBD
cord-010570-ytv7dwr0	134	7	then	then	RB
cord-010570-ytv7dwr0	134	8	hampered	hamper	VBN
cord-010570-ytv7dwr0	134	9	by	by	IN
cord-010570-ytv7dwr0	134	10	the	the	DT
cord-010570-ytv7dwr0	134	11	lack	lack	NN
cord-010570-ytv7dwr0	134	12	of	of	IN
cord-010570-ytv7dwr0	134	13	useful	useful	JJ
cord-010570-ytv7dwr0	134	14	animal	animal	NN
cord-010570-ytv7dwr0	134	15	models	model	NNS
cord-010570-ytv7dwr0	134	16	,	,	,
cord-010570-ytv7dwr0	134	17	loss	loss	NN
cord-010570-ytv7dwr0	134	18	of	of	IN
cord-010570-ytv7dwr0	134	19	strain	strain	NN
cord-010570-ytv7dwr0	134	20	virulence	virulence	NN
cord-010570-ytv7dwr0	134	21	in	in	IN
cord-010570-ytv7dwr0	134	22	vitro	vitro	FW
cord-010570-ytv7dwr0	134	23	,	,	,
cord-010570-ytv7dwr0	134	24	and	and	CC
cord-010570-ytv7dwr0	134	25	poor	poor	JJ
cord-010570-ytv7dwr0	134	26	understanding	understanding	NN
cord-010570-ytv7dwr0	134	27	of	of	IN
cord-010570-ytv7dwr0	134	28	the	the	DT
cord-010570-ytv7dwr0	134	29	antigenic	antigenic	JJ
cord-010570-ytv7dwr0	134	30	diversity	diversity	NN
cord-010570-ytv7dwr0	134	31	of	of	IN
cord-010570-ytv7dwr0	134	32	N	n	CD
cord-010570-ytv7dwr0	134	33	meningitidis	meningitidis	NNP
cord-010570-ytv7dwr0	134	34	[	[	-LRB-
cord-010570-ytv7dwr0	134	35	105	105	CD
cord-010570-ytv7dwr0	134	36	,	,	,
cord-010570-ytv7dwr0	134	37	106	106	CD
cord-010570-ytv7dwr0	134	38	]	]	-RRB-
cord-010570-ytv7dwr0	134	39	.	.	.
cord-010570-ytv7dwr0	135	1	A	a	DT
cord-010570-ytv7dwr0	135	2	lesson	lesson	NN
cord-010570-ytv7dwr0	135	3	from	from	IN
cord-010570-ytv7dwr0	135	4	the	the	DT
cord-010570-ytv7dwr0	135	5	preantibiotic	preantibiotic	JJ
cord-010570-ytv7dwr0	135	6	era	era	NN
cord-010570-ytv7dwr0	135	7	is	be	VBZ
cord-010570-ytv7dwr0	135	8	that	that	IN
cord-010570-ytv7dwr0	135	9	a	a	DT
cord-010570-ytv7dwr0	135	10	considerable	considerable	JJ
cord-010570-ytv7dwr0	135	11	amount	amount	NN
cord-010570-ytv7dwr0	135	12	of	of	IN
cord-010570-ytv7dwr0	135	13	basic	basic	JJ
cord-010570-ytv7dwr0	135	14	research	research	NN
cord-010570-ytv7dwr0	135	15	on	on	IN
cord-010570-ytv7dwr0	135	16	the	the	DT
cord-010570-ytv7dwr0	135	17	immunology	immunology	NN
cord-010570-ytv7dwr0	135	18	and	and	CC
cord-010570-ytv7dwr0	135	19	pathogenesis	pathogenesis	NN
cord-010570-ytv7dwr0	135	20	of	of	IN
cord-010570-ytv7dwr0	135	21	each	each	DT
cord-010570-ytv7dwr0	135	22	infection	infection	NN
cord-010570-ytv7dwr0	135	23	is	be	VBZ
cord-010570-ytv7dwr0	135	24	usually	usually	RB
cord-010570-ytv7dwr0	135	25	necessary	necessary	JJ
cord-010570-ytv7dwr0	135	26	before	before	IN
cord-010570-ytv7dwr0	135	27	antibody	antibody	NN
cord-010570-ytv7dwr0	135	28	therapy	therapy	NN
cord-010570-ytv7dwr0	135	29	can	can	MD
cord-010570-ytv7dwr0	135	30	be	be	VB
cord-010570-ytv7dwr0	135	31	developed	develop	VBN
cord-010570-ytv7dwr0	135	32	that	that	WDT
cord-010570-ytv7dwr0	135	33	will	will	MD
cord-010570-ytv7dwr0	135	34	be	be	VB
cord-010570-ytv7dwr0	135	35	successful	successful	JJ
cord-010570-ytv7dwr0	135	36	in	in	IN
cord-010570-ytv7dwr0	135	37	clinical	clinical	JJ
cord-010570-ytv7dwr0	135	38	practice	practice	NN
cord-010570-ytv7dwr0	135	39	.	.	.
cord-010570-ytv7dwr0	136	1	Spectrum	Spectrum	NNP
cord-010570-ytv7dwr0	136	2	ofactivity	ofactivity	NN
cord-010570-ytv7dwr0	136	3	.	.	.
cord-010570-ytv7dwr0	137	1	Antibodies	antibody	NNS
cord-010570-ytv7dwr0	137	2	can	can	MD
cord-010570-ytv7dwr0	137	3	modify	modify	VB
cord-010570-ytv7dwr0	137	4	bacterial	bacterial	JJ
cord-010570-ytv7dwr0	137	5	,	,	,
cord-010570-ytv7dwr0	137	6	fungal	fungal	JJ
cord-010570-ytv7dwr0	137	7	,	,	,
cord-010570-ytv7dwr0	137	8	parasitic	parasitic	JJ
cord-010570-ytv7dwr0	137	9	,	,	,
cord-010570-ytv7dwr0	137	10	and	and	CC
cord-010570-ytv7dwr0	137	11	viral	viral	JJ
cord-010570-ytv7dwr0	137	12	infections	infection	NNS
cord-010570-ytv7dwr0	137	13	and	and	CC
cord-010570-ytv7dwr0	137	14	are	be	VBP
cord-010570-ytv7dwr0	137	15	a	a	DT
cord-010570-ytv7dwr0	137	16	class	class	NN
cord-010570-ytv7dwr0	137	17	of	of	IN
cord-010570-ytv7dwr0	137	18	biological	biological	JJ
cord-010570-ytv7dwr0	137	19	agents	agent	NNS
cord-010570-ytv7dwr0	137	20	with	with	IN
cord-010570-ytv7dwr0	137	21	broad	broad	JJ
cord-010570-ytv7dwr0	137	22	antimicrobial	antimicrobial	JJ
cord-010570-ytv7dwr0	137	23	activity	activity	NN
cord-010570-ytv7dwr0	137	24	against	against	IN
cord-010570-ytv7dwr0	137	25	diverse	diverse	JJ
cord-010570-ytv7dwr0	137	26	pathogens	pathogen	NNS
cord-010570-ytv7dwr0	137	27	.	.	.
cord-010570-ytv7dwr0	138	1	Antibody	antibody	NN
cord-010570-ytv7dwr0	138	2	-	-	HYPH
cord-010570-ytv7dwr0	138	3	based	base	VBN
cord-010570-ytv7dwr0	138	4	therapies	therapy	NNS
cord-010570-ytv7dwr0	138	5	are	be	VBP
cord-010570-ytv7dwr0	138	6	usually	usually	RB
cord-010570-ytv7dwr0	138	7	pathogen	pathogen	NN
cord-010570-ytv7dwr0	138	8	-	-	HYPH
cord-010570-ytv7dwr0	138	9	specific	specific	JJ
cord-010570-ytv7dwr0	138	10	and	and	CC
cord-010570-ytv7dwr0	138	11	have	have	VB
cord-010570-ytv7dwr0	138	12	the	the	DT
cord-010570-ytv7dwr0	138	13	theoretical	theoretical	JJ
cord-010570-ytv7dwr0	138	14	advantage	advantage	NN
cord-010570-ytv7dwr0	138	15	that	that	IN
cord-010570-ytv7dwr0	138	16	they	-PRON-	PRP
cord-010570-ytv7dwr0	138	17	should	should	MD
cord-010570-ytv7dwr0	138	18	not	not	RB
cord-010570-ytv7dwr0	138	19	affect	affect	VB
cord-010570-ytv7dwr0	138	20	the	the	DT
cord-010570-ytv7dwr0	138	21	normal	normal	JJ
cord-010570-ytv7dwr0	138	22	flora	flora	NNS
cord-010570-ytv7dwr0	138	23	of	of	IN
cord-010570-ytv7dwr0	138	24	the	the	DT
cord-010570-ytv7dwr0	138	25	patient	patient	NN
cord-010570-ytv7dwr0	138	26	or	or	CC
cord-010570-ytv7dwr0	138	27	select	select	VB
cord-010570-ytv7dwr0	138	28	for	for	IN
cord-010570-ytv7dwr0	138	29	resistance	resistance	NN
cord-010570-ytv7dwr0	138	30	in	in	IN
cord-010570-ytv7dwr0	138	31	nontargeted	nontargeted	JJ
cord-010570-ytv7dwr0	138	32	microbes	microbe	NNS
cord-010570-ytv7dwr0	138	33	.	.	.
cord-010570-ytv7dwr0	139	1	Nevertheless	nevertheless	RB
cord-010570-ytv7dwr0	139	2	,	,	,
cord-010570-ytv7dwr0	139	3	narrow	narrow	JJ
cord-010570-ytv7dwr0	139	4	specificity	specificity	NN
cord-010570-ytv7dwr0	139	5	is	be	VBZ
cord-010570-ytv7dwr0	139	6	a	a	DT
cord-010570-ytv7dwr0	139	7	disadvantage	disadvantage	NN
cord-010570-ytv7dwr0	139	8	because	because	IN
cord-010570-ytv7dwr0	139	9	mixed	mixed	JJ
cord-010570-ytv7dwr0	139	10	infections	infection	NNS
cord-010570-ytv7dwr0	139	11	may	may	MD
cord-010570-ytv7dwr0	139	12	not	not	RB
cord-010570-ytv7dwr0	139	13	be	be	VB
cord-010570-ytv7dwr0	139	14	treated	treat	VBN
cord-010570-ytv7dwr0	139	15	by	by	IN
cord-010570-ytv7dwr0	139	16	a	a	DT
cord-010570-ytv7dwr0	139	17	single	single	JJ
cord-010570-ytv7dwr0	139	18	antibody	antibody	NN
cord-010570-ytv7dwr0	139	19	preparation	preparation	NN
cord-010570-ytv7dwr0	139	20	.	.	.
cord-010570-ytv7dwr0	140	1	Pneumonia	pneumonia	NN
cord-010570-ytv7dwr0	140	2	due	due	IN
cord-010570-ytv7dwr0	140	3	to	to	IN
cord-010570-ytv7dwr0	140	4	S.	S.	NNP
cord-010570-ytv7dwr0	140	5	pneumoniae	pneumoniae	NN
cord-010570-ytv7dwr0	140	6	with	with	IN
cord-010570-ytv7dwr0	140	7	more	more	JJR
cord-010570-ytv7dwr0	140	8	than	than	IN
cord-010570-ytv7dwr0	140	9	one	one	CD
cord-010570-ytv7dwr0	140	10	serotype	serotype	NN
cord-010570-ytv7dwr0	140	11	was	be	VBD
cord-010570-ytv7dwr0	140	12	recognized	recognize	VBN
cord-010570-ytv7dwr0	140	13	as	as	IN
cord-010570-ytv7dwr0	140	14	a	a	DT
cord-010570-ytv7dwr0	140	15	reason	reason	NN
cord-010570-ytv7dwr0	140	16	for	for	IN
cord-010570-ytv7dwr0	140	17	the	the	DT
cord-010570-ytv7dwr0	140	18	failure	failure	NN
cord-010570-ytv7dwr0	140	19	of	of	IN
cord-010570-ytv7dwr0	140	20	type	type	NN
cord-010570-ytv7dwr0	140	21	-	-	HYPH
cord-010570-ytv7dwr0	140	22	specific	specific	JJ
cord-010570-ytv7dwr0	140	23	serum	serum	NN
cord-010570-ytv7dwr0	140	24	therapy	therapy	NN
cord-010570-ytv7dwr0	140	25	[	[	-LRB-
cord-010570-ytv7dwr0	140	26	107	107	CD
cord-010570-ytv7dwr0	140	27	]	]	-RRB-
cord-010570-ytv7dwr0	140	28	.	.	.
cord-010570-ytv7dwr0	141	1	One	one	CD
cord-010570-ytv7dwr0	141	2	solution	solution	NN
cord-010570-ytv7dwr0	141	3	is	be	VBZ
cord-010570-ytv7dwr0	141	4	to	to	TO
cord-010570-ytv7dwr0	141	5	use	use	VB
cord-010570-ytv7dwr0	141	6	cocktails	cocktail	NNS
cord-010570-ytv7dwr0	141	7	of	of	IN
cord-010570-ytv7dwr0	141	8	mAbs	mabs	NN
cord-010570-ytv7dwr0	141	9	active	active	JJ
cord-010570-ytv7dwr0	141	10	against	against	IN
cord-010570-ytv7dwr0	141	11	common	common	JJ
cord-010570-ytv7dwr0	141	12	antigenic	antigenic	JJ
cord-010570-ytv7dwr0	141	13	types	type	NNS
cord-010570-ytv7dwr0	141	14	.	.	.
cord-010570-ytv7dwr0	142	1	Cocktails	cocktail	NNS
cord-010570-ytv7dwr0	142	2	may	may	MD
cord-010570-ytv7dwr0	142	3	be	be	VB
cord-010570-ytv7dwr0	142	4	designed	design	VBN
cord-010570-ytv7dwr0	142	5	to	to	TO
cord-010570-ytv7dwr0	142	6	include	include	VB
cord-010570-ytv7dwr0	142	7	mAbs	mAbs	NNP
cord-010570-ytv7dwr0	142	8	to	to	IN
cord-010570-ytv7dwr0	142	9	multiple	multiple	JJ
cord-010570-ytv7dwr0	142	10	serotypes	serotype	NNS
cord-010570-ytv7dwr0	142	11	and	and	CC
cord-010570-ytv7dwr0	142	12	mAbs	mabs	NN
cord-010570-ytv7dwr0	142	13	with	with	IN
cord-010570-ytv7dwr0	142	14	multiple	multiple	JJ
cord-010570-ytv7dwr0	142	15	isotypes	isotype	NNS
cord-010570-ytv7dwr0	142	16	to	to	TO
cord-010570-ytv7dwr0	142	17	enhance	enhance	VB
cord-010570-ytv7dwr0	142	18	antibody	antibody	NN
cord-010570-ytv7dwr0	142	19	effector	effector	NN
cord-010570-ytv7dwr0	142	20	function	function	NN
cord-010570-ytv7dwr0	142	21	.	.	.
cord-010570-ytv7dwr0	143	1	Pathogen	pathogen	NN
cord-010570-ytv7dwr0	143	2	-	-	HYPH
cord-010570-ytv7dwr0	143	3	specific	specific	JJ
cord-010570-ytv7dwr0	143	4	drugs	drug	NNS
cord-010570-ytv7dwr0	143	5	(	(	-LRB-
cord-010570-ytv7dwr0	143	6	such	such	JJ
cord-010570-ytv7dwr0	143	7	as	as	IN
cord-010570-ytv7dwr0	143	8	mAbs	mAbs	NNP
cord-010570-ytv7dwr0	143	9	)	)	-RRB-
cord-010570-ytv7dwr0	143	10	are	be	VBP
cord-010570-ytv7dwr0	143	11	less	less	RBR
cord-010570-ytv7dwr0	143	12	attractive	attractive	JJ
cord-010570-ytv7dwr0	143	13	to	to	IN
cord-010570-ytv7dwr0	143	14	the	the	DT
cord-010570-ytv7dwr0	143	15	pharmaceutical	pharmaceutical	JJ
cord-010570-ytv7dwr0	143	16	industry	industry	NN
cord-010570-ytv7dwr0	143	17	because	because	IN
cord-010570-ytv7dwr0	143	18	the	the	DT
cord-010570-ytv7dwr0	143	19	narrow	narrow	JJ
cord-010570-ytv7dwr0	143	20	specificity	specificity	NN
cord-010570-ytv7dwr0	143	21	reduces	reduce	VBZ
cord-010570-ytv7dwr0	143	22	the	the	DT
cord-010570-ytv7dwr0	143	23	potential	potential	JJ
cord-010570-ytv7dwr0	143	24	market	market	NN
cord-010570-ytv7dwr0	143	25	for	for	IN
cord-010570-ytv7dwr0	143	26	the	the	DT
cord-010570-ytv7dwr0	143	27	drug	drug	NN
cord-010570-ytv7dwr0	143	28	.	.	.
cord-010570-ytv7dwr0	144	1	However	however	RB
cord-010570-ytv7dwr0	144	2	,	,	,
cord-010570-ytv7dwr0	144	3	the	the	DT
cord-010570-ytv7dwr0	144	4	increasing	increase	VBG
cord-010570-ytv7dwr0	144	5	incidence	incidence	NN
cord-010570-ytv7dwr0	144	6	of	of	IN
cord-010570-ytv7dwr0	144	7	resistant	resistant	JJ
cord-010570-ytv7dwr0	144	8	organisms	organism	NNS
cord-010570-ytv7dwr0	144	9	resulting	result	VBG
cord-010570-ytv7dwr0	144	10	from	from	IN
cord-010570-ytv7dwr0	144	11	the	the	DT
cord-010570-ytv7dwr0	144	12	use	use	NN
cord-010570-ytv7dwr0	144	13	of	of	IN
cord-010570-ytv7dwr0	144	14	broad	broad	JJ
cord-010570-ytv7dwr0	144	15	-	-	HYPH
cord-010570-ytv7dwr0	144	16	spectrum	spectrum	NN
cord-010570-ytv7dwr0	144	17	antibiotic	antibiotic	NN
cord-010570-ytv7dwr0	144	18	regimens	regimen	NNS
cord-010570-ytv7dwr0	144	19	could	could	MD
cord-010570-ytv7dwr0	144	20	make	make	VB
cord-010570-ytv7dwr0	144	21	pathogen	pathogen	NN
cord-010570-ytv7dwr0	144	22	-	-	HYPH
cord-010570-ytv7dwr0	144	23	specific	specific	JJ
cord-010570-ytv7dwr0	144	24	drugs	drug	NNS
cord-010570-ytv7dwr0	144	25	attractive	attractive	JJ
cord-010570-ytv7dwr0	144	26	to	to	IN
cord-010570-ytv7dwr0	144	27	drug	drug	NN
cord-010570-ytv7dwr0	144	28	companies	company	NNS
cord-010570-ytv7dwr0	144	29	.	.	.
cord-010570-ytv7dwr0	145	1	Precedents	precedent	NNS
cord-010570-ytv7dwr0	145	2	for	for	IN
cord-010570-ytv7dwr0	145	3	the	the	DT
cord-010570-ytv7dwr0	145	4	development	development	NN
cord-010570-ytv7dwr0	145	5	of	of	IN
cord-010570-ytv7dwr0	145	6	pathogen	pathogen	NN
cord-010570-ytv7dwr0	145	7	-	-	HYPH
cord-010570-ytv7dwr0	145	8	specific	specific	JJ
cord-010570-ytv7dwr0	145	9	drugs	drug	NNS
cord-010570-ytv7dwr0	145	10	already	already	RB
cord-010570-ytv7dwr0	145	11	exist	exist	VBP
cord-010570-ytv7dwr0	145	12	in	in	IN
cord-010570-ytv7dwr0	145	13	the	the	DT
cord-010570-ytv7dwr0	145	14	area	area	NN
cord-010570-ytv7dwr0	145	15	of	of	IN
cord-010570-ytv7dwr0	145	16	antiviral	antiviral	JJ
cord-010570-ytv7dwr0	145	17	drug	drug	NN
cord-010570-ytv7dwr0	145	18	research	research	NN
cord-010570-ytv7dwr0	145	19	.	.	.
cord-010570-ytv7dwr0	146	1	Mechanisms	mechanism	NNS
cord-010570-ytv7dwr0	146	2	ofaction	ofaction	NN
cord-010570-ytv7dwr0	146	3	.	.	.
cord-010570-ytv7dwr0	147	1	Antibodies	antibody	NNS
cord-010570-ytv7dwr0	147	2	mediate	mediate	VBP
cord-010570-ytv7dwr0	147	3	protection	protection	NN
cord-010570-ytv7dwr0	147	4	by	by	IN
cord-010570-ytv7dwr0	147	5	a	a	DT
cord-010570-ytv7dwr0	147	6	variety	variety	NN
cord-010570-ytv7dwr0	147	7	of	of	IN
cord-010570-ytv7dwr0	147	8	mechanisms	mechanism	NNS
cord-010570-ytv7dwr0	147	9	.	.	.
cord-010570-ytv7dwr0	148	1	Direct	direct	JJ
cord-010570-ytv7dwr0	148	2	antibody	antibody	NN
cord-010570-ytv7dwr0	148	3	mechanisms	mechanism	NNS
cord-010570-ytv7dwr0	148	4	of	of	IN
cord-010570-ytv7dwr0	148	5	action	action	NN
cord-010570-ytv7dwr0	148	6	include	include	VBP
cord-010570-ytv7dwr0	148	7	inhibition	inhibition	NN
cord-010570-ytv7dwr0	148	8	of	of	IN
cord-010570-ytv7dwr0	148	9	attachment	attachment	NN
cord-010570-ytv7dwr0	148	10	,	,	,
cord-010570-ytv7dwr0	148	11	agglutination	agglutination	NN
cord-010570-ytv7dwr0	148	12	(	(	-LRB-
cord-010570-ytv7dwr0	148	13	and	and	CC
cord-010570-ytv7dwr0	148	14	immobili	immobili	NNP
cord-010570-ytv7dwr0	148	15	-	-	HYPH
cord-010570-ytv7dwr0	148	16	cm	cm	NNP
cord-010570-ytv7dwr0	148	17	1995;21	1995;21	CD
cord-010570-ytv7dwr0	148	18	(	(	-LRB-
cord-010570-ytv7dwr0	148	19	July	July	NNP
cord-010570-ytv7dwr0	148	20	)	)	-RRB-
cord-010570-ytv7dwr0	148	21	zation	zation	NNP
cord-010570-ytv7dwr0	148	22	)	)	-RRB-
cord-010570-ytv7dwr0	148	23	,	,	,
cord-010570-ytv7dwr0	148	24	viral	viral	JJ
cord-010570-ytv7dwr0	148	25	neutralization	neutralization	NN
cord-010570-ytv7dwr0	148	26	,	,	,
cord-010570-ytv7dwr0	148	27	toxin	toxin	NN
cord-010570-ytv7dwr0	148	28	neutralization	neutralization	NN
cord-010570-ytv7dwr0	148	29	,	,	,
cord-010570-ytv7dwr0	148	30	antibodydirected	antibodydirecte	VBN
cord-010570-ytv7dwr0	148	31	cellular	cellular	JJ
cord-010570-ytv7dwr0	148	32	cytotoxicity	cytotoxicity	NN
cord-010570-ytv7dwr0	148	33	,	,	,
cord-010570-ytv7dwr0	148	34	complement	complement	NN
cord-010570-ytv7dwr0	148	35	activation	activation	NN
cord-010570-ytv7dwr0	148	36	,	,	,
cord-010570-ytv7dwr0	148	37	and	and	CC
cord-010570-ytv7dwr0	148	38	opsonization	opsonization	NN
cord-010570-ytv7dwr0	148	39	[	[	-LRB-
cord-010570-ytv7dwr0	148	40	108	108	CD
cord-010570-ytv7dwr0	148	41	]	]	-RRB-
cord-010570-ytv7dwr0	148	42	.	.	.
cord-010570-ytv7dwr0	149	1	Antibody	antibody	NN
cord-010570-ytv7dwr0	149	2	therapy	therapy	NN
cord-010570-ytv7dwr0	149	3	has	have	VBZ
cord-010570-ytv7dwr0	149	4	the	the	DT
cord-010570-ytv7dwr0	149	5	potential	potential	NN
cord-010570-ytv7dwr0	149	6	to	to	TO
cord-010570-ytv7dwr0	149	7	enhance	enhance	VB
cord-010570-ytv7dwr0	149	8	immune	immune	JJ
cord-010570-ytv7dwr0	149	9	function	function	NN
cord-010570-ytv7dwr0	149	10	in	in	IN
cord-010570-ytv7dwr0	149	11	immunosuppressed	immunosuppressed	JJ
cord-010570-ytv7dwr0	149	12	hosts	host	NNS
cord-010570-ytv7dwr0	149	13	.	.	.
cord-010570-ytv7dwr0	150	1	However	however	RB
cord-010570-ytv7dwr0	150	2	,	,	,
cord-010570-ytv7dwr0	150	3	since	since	IN
cord-010570-ytv7dwr0	150	4	the	the	DT
cord-010570-ytv7dwr0	150	5	mechanism	mechanism	NN
cord-010570-ytv7dwr0	150	6	of	of	IN
cord-010570-ytv7dwr0	150	7	action	action	NN
cord-010570-ytv7dwr0	150	8	of	of	IN
cord-010570-ytv7dwr0	150	9	many	many	JJ
cord-010570-ytv7dwr0	150	10	antibodies	antibody	NNS
cord-010570-ytv7dwr0	150	11	involves	involve	VBZ
cord-010570-ytv7dwr0	150	12	promoting	promote	VBG
cord-010570-ytv7dwr0	150	13	microbial	microbial	JJ
cord-010570-ytv7dwr0	150	14	clearance	clearance	NN
cord-010570-ytv7dwr0	150	15	through	through	IN
cord-010570-ytv7dwr0	150	16	nonspecific	nonspecific	JJ
cord-010570-ytv7dwr0	150	17	cellular	cellular	JJ
cord-010570-ytv7dwr0	150	18	immunity	immunity	NN
cord-010570-ytv7dwr0	150	19	,	,	,
cord-010570-ytv7dwr0	150	20	antibody	antibody	NN
cord-010570-ytv7dwr0	150	21	-	-	HYPH
cord-010570-ytv7dwr0	150	22	based	base	VBN
cord-010570-ytv7dwr0	150	23	therapies	therapy	NNS
cord-010570-ytv7dwr0	150	24	may	may	MD
cord-010570-ytv7dwr0	150	25	be	be	VB
cord-010570-ytv7dwr0	150	26	less	less	RBR
cord-010570-ytv7dwr0	150	27	effective	effective	JJ
cord-010570-ytv7dwr0	150	28	in	in	IN
cord-010570-ytv7dwr0	150	29	individuals	individual	NNS
cord-010570-ytv7dwr0	150	30	with	with	IN
cord-010570-ytv7dwr0	150	31	defective	defective	JJ
cord-010570-ytv7dwr0	150	32	macrophage	macrophage	NN
cord-010570-ytv7dwr0	150	33	,	,	,
cord-010570-ytv7dwr0	150	34	neutrophil	neutrophil	NN
cord-010570-ytv7dwr0	150	35	,	,	,
cord-010570-ytv7dwr0	150	36	and	and	CC
cord-010570-ytv7dwr0	150	37	natural	natural	JJ
cord-010570-ytv7dwr0	150	38	killer	killer	NN
cord-010570-ytv7dwr0	150	39	cell	cell	NN
cord-010570-ytv7dwr0	150	40	function	function	NN
cord-010570-ytv7dwr0	150	41	.	.	.
cord-010570-ytv7dwr0	151	1	In	in	IN
cord-010570-ytv7dwr0	151	2	this	this	DT
cord-010570-ytv7dwr0	151	3	regard	regard	NN
cord-010570-ytv7dwr0	151	4	,	,	,
cord-010570-ytv7dwr0	151	5	it	-PRON-	PRP
cord-010570-ytv7dwr0	151	6	is	be	VBZ
cord-010570-ytv7dwr0	151	7	encouraging	encouraging	JJ
cord-010570-ytv7dwr0	151	8	that	that	IN
cord-010570-ytv7dwr0	151	9	antibodies	antibody	NNS
cord-010570-ytv7dwr0	151	10	are	be	VBP
cord-010570-ytv7dwr0	151	11	effective	effective	JJ
cord-010570-ytv7dwr0	151	12	against	against	IN
cord-010570-ytv7dwr0	151	13	Pseudomonas	Pseudomonas	NNP
cord-010570-ytv7dwr0	151	14	aeruginosa	aeruginosa	NN
cord-010570-ytv7dwr0	151	15	in	in	IN
cord-010570-ytv7dwr0	151	16	neutropenic	neutropenic	JJ
cord-010570-ytv7dwr0	151	17	mice	mouse	NNS
cord-010570-ytv7dwr0	151	18	[	[	-LRB-
cord-010570-ytv7dwr0	151	19	109	109	CD
cord-010570-ytv7dwr0	151	20	]	]	-RRB-
cord-010570-ytv7dwr0	151	21	and	and	CC
cord-010570-ytv7dwr0	151	22	that	that	IN
cord-010570-ytv7dwr0	151	23	they	-PRON-	PRP
cord-010570-ytv7dwr0	151	24	can	can	MD
cord-010570-ytv7dwr0	151	25	reduce	reduce	VB
cord-010570-ytv7dwr0	151	26	the	the	DT
cord-010570-ytv7dwr0	151	27	number	number	NN
cord-010570-ytv7dwr0	151	28	of	of	IN
cord-010570-ytv7dwr0	151	29	infections	infection	NNS
cord-010570-ytv7dwr0	151	30	in	in	IN
cord-010570-ytv7dwr0	151	31	pediatric	pediatric	JJ
cord-010570-ytv7dwr0	151	32	patients	patient	NNS
cord-010570-ytv7dwr0	151	33	with	with	IN
cord-010570-ytv7dwr0	151	34	AIDS	AIDS	NNP
cord-010570-ytv7dwr0	151	35	[	[	-LRB-
cord-010570-ytv7dwr0	151	36	79	79	CD
cord-010570-ytv7dwr0	151	37	]	]	-RRB-
cord-010570-ytv7dwr0	151	38	.	.	.
cord-010570-ytv7dwr0	152	1	Antibodies	antibody	NNS
cord-010570-ytv7dwr0	152	2	are	be	VBP
cord-010570-ytv7dwr0	152	3	usually	usually	RB
cord-010570-ytv7dwr0	152	4	considered	consider	VBN
cord-010570-ytv7dwr0	152	5	to	to	TO
cord-010570-ytv7dwr0	152	6	be	be	VB
cord-010570-ytv7dwr0	152	7	"	"	``
cord-010570-ytv7dwr0	152	8	protective	protective	JJ
cord-010570-ytv7dwr0	152	9	"	"	''
cord-010570-ytv7dwr0	152	10	effector	effector	NN
cord-010570-ytv7dwr0	152	11	molecules	molecule	NNS
cord-010570-ytv7dwr0	152	12	of	of	IN
cord-010570-ytv7dwr0	152	13	the	the	DT
cord-010570-ytv7dwr0	152	14	immune	immune	JJ
cord-010570-ytv7dwr0	152	15	system	system	NN
cord-010570-ytv7dwr0	152	16	.	.	.
cord-010570-ytv7dwr0	153	1	However	however	RB
cord-010570-ytv7dwr0	153	2	,	,	,
cord-010570-ytv7dwr0	153	3	not	not	RB
cord-010570-ytv7dwr0	153	4	all	all	DT
cord-010570-ytv7dwr0	153	5	antibody	antibody	NN
cord-010570-ytv7dwr0	153	6	responses	response	NNS
cord-010570-ytv7dwr0	153	7	to	to	IN
cord-010570-ytv7dwr0	153	8	pathogens	pathogen	NNS
cord-010570-ytv7dwr0	153	9	are	be	VBP
cord-010570-ytv7dwr0	153	10	protective	protective	JJ
cord-010570-ytv7dwr0	153	11	and	and	CC
cord-010570-ytv7dwr0	153	12	some	some	DT
cord-010570-ytv7dwr0	153	13	may	may	MD
cord-010570-ytv7dwr0	153	14	be	be	VB
cord-010570-ytv7dwr0	153	15	deleterious	deleterious	JJ
cord-010570-ytv7dwr0	153	16	to	to	IN
cord-010570-ytv7dwr0	153	17	the	the	DT
cord-010570-ytv7dwr0	153	18	host	host	NN
cord-010570-ytv7dwr0	153	19	.	.	.
cord-010570-ytv7dwr0	154	1	For	for	IN
cord-010570-ytv7dwr0	154	2	example	example	NN
cord-010570-ytv7dwr0	154	3	,	,	,
cord-010570-ytv7dwr0	154	4	some	some	DT
cord-010570-ytv7dwr0	154	5	viral	viral	JJ
cord-010570-ytv7dwr0	154	6	-	-	HYPH
cord-010570-ytv7dwr0	154	7	specific	specific	JJ
cord-010570-ytv7dwr0	154	8	antibodies	antibody	NNS
cord-010570-ytv7dwr0	154	9	are	be	VBP
cord-010570-ytv7dwr0	154	10	capable	capable	JJ
cord-010570-ytv7dwr0	154	11	of	of	IN
cord-010570-ytv7dwr0	154	12	enhancing	enhance	VBG
cord-010570-ytv7dwr0	154	13	infection	infection	NN
cord-010570-ytv7dwr0	154	14	[	[	-LRB-
cord-010570-ytv7dwr0	154	15	110	110	CD
cord-010570-ytv7dwr0	154	16	]	]	-RRB-
cord-010570-ytv7dwr0	154	17	.	.	.
cord-010570-ytv7dwr0	155	1	Thus	thus	RB
cord-010570-ytv7dwr0	155	2	,	,	,
cord-010570-ytv7dwr0	155	3	antibody	antibody	NN
cord-010570-ytv7dwr0	155	4	molecules	molecule	NNS
cord-010570-ytv7dwr0	155	5	being	be	VBG
cord-010570-ytv7dwr0	155	6	considered	consider	VBN
cord-010570-ytv7dwr0	155	7	for	for	IN
cord-010570-ytv7dwr0	155	8	clinical	clinical	JJ
cord-010570-ytv7dwr0	155	9	development	development	NN
cord-010570-ytv7dwr0	155	10	will	will	MD
cord-010570-ytv7dwr0	155	11	require	require	VB
cord-010570-ytv7dwr0	155	12	extensive	extensive	JJ
cord-010570-ytv7dwr0	155	13	testing	testing	NN
cord-010570-ytv7dwr0	155	14	in	in	IN
cord-010570-ytv7dwr0	155	15	vitro	vitro	FW
cord-010570-ytv7dwr0	155	16	and	and	CC
cord-010570-ytv7dwr0	155	17	in	in	IN
cord-010570-ytv7dwr0	155	18	vivo	vivo	NNP
cord-010570-ytv7dwr0	155	19	.	.	.
cord-010570-ytv7dwr0	156	1	Studies	study	NNS
cord-010570-ytv7dwr0	156	2	of	of	IN
cord-010570-ytv7dwr0	156	3	the	the	DT
cord-010570-ytv7dwr0	156	4	mechanisms	mechanism	NNS
cord-010570-ytv7dwr0	156	5	of	of	IN
cord-010570-ytv7dwr0	156	6	antibody	antibody	NN
cord-010570-ytv7dwr0	156	7	action	action	NN
cord-010570-ytv7dwr0	156	8	are	be	VBP
cord-010570-ytv7dwr0	156	9	important	important	JJ
cord-010570-ytv7dwr0	156	10	for	for	IN
cord-010570-ytv7dwr0	156	11	understanding	understand	VBG
cord-010570-ytv7dwr0	156	12	the	the	DT
cord-010570-ytv7dwr0	156	13	mode	mode	NN
cord-010570-ytv7dwr0	156	14	of	of	IN
cord-010570-ytv7dwr0	156	15	protection	protection	NN
cord-010570-ytv7dwr0	156	16	and	and	CC
cord-010570-ytv7dwr0	156	17	for	for	IN
cord-010570-ytv7dwr0	156	18	designing	design	VBG
cord-010570-ytv7dwr0	156	19	clinical	clinical	JJ
cord-010570-ytv7dwr0	156	20	trials	trial	NNS
cord-010570-ytv7dwr0	156	21	.	.	.
cord-010570-ytv7dwr0	157	1	Pharmacokinetics	Pharmacokinetics	NNP
cord-010570-ytv7dwr0	157	2	.	.	.
cord-010570-ytv7dwr0	158	1	The	the	DT
cord-010570-ytv7dwr0	158	2	pharmacokinetics	pharmacokinetic	NNS
cord-010570-ytv7dwr0	158	3	of	of	IN
cord-010570-ytv7dwr0	158	4	human	human	JJ
cord-010570-ytv7dwr0	158	5	IgG	IgG	NNP
cord-010570-ytv7dwr0	158	6	suggests	suggest	VBZ
cord-010570-ytv7dwr0	158	7	several	several	JJ
cord-010570-ytv7dwr0	158	8	useful	useful	JJ
cord-010570-ytv7dwr0	158	9	characteristics	characteristic	NNS
cord-010570-ytv7dwr0	158	10	for	for	IN
cord-010570-ytv7dwr0	158	11	its	-PRON-	PRP$
cord-010570-ytv7dwr0	158	12	role	role	NN
cord-010570-ytv7dwr0	158	13	as	as	IN
cord-010570-ytv7dwr0	158	14	an	an	DT
cord-010570-ytv7dwr0	158	15	antiinfective	antiinfective	JJ
cord-010570-ytv7dwr0	158	16	agent	agent	NN
cord-010570-ytv7dwr0	158	17	.	.	.
cord-010570-ytv7dwr0	159	1	These	these	DT
cord-010570-ytv7dwr0	159	2	include	include	VBP
cord-010570-ytv7dwr0	159	3	a	a	DT
cord-010570-ytv7dwr0	159	4	long	long	JJ
cord-010570-ytv7dwr0	159	5	half	half	JJ
cord-010570-ytv7dwr0	159	6	-	-	HYPH
cord-010570-ytv7dwr0	159	7	life	life	NN
cord-010570-ytv7dwr0	159	8	(	(	-LRB-
cord-010570-ytv7dwr0	159	9	~20	~20	NFP
cord-010570-ytv7dwr0	159	10	days	day	NNS
cord-010570-ytv7dwr0	159	11	[	[	-LRB-
cord-010570-ytv7dwr0	159	12	111	111	CD
cord-010570-ytv7dwr0	159	13	]	]	-RRB-
cord-010570-ytv7dwr0	159	14	)	)	-RRB-
cord-010570-ytv7dwr0	159	15	,	,	,
cord-010570-ytv7dwr0	159	16	good	good	JJ
cord-010570-ytv7dwr0	159	17	tissue	tissue	NN
cord-010570-ytv7dwr0	159	18	penetration	penetration	NN
cord-010570-ytv7dwr0	159	19	[	[	-LRB-
cord-010570-ytv7dwr0	159	20	112	112	CD
cord-010570-ytv7dwr0	159	21	]	]	-RRB-
cord-010570-ytv7dwr0	159	22	,	,	,
cord-010570-ytv7dwr0	159	23	and	and	CC
cord-010570-ytv7dwr0	159	24	,	,	,
cord-010570-ytv7dwr0	159	25	depending	depend	VBG
cord-010570-ytv7dwr0	159	26	on	on	IN
cord-010570-ytv7dwr0	159	27	the	the	DT
cord-010570-ytv7dwr0	159	28	isotype	isotype	NN
cord-010570-ytv7dwr0	159	29	,	,	,
cord-010570-ytv7dwr0	159	30	the	the	DT
cord-010570-ytv7dwr0	159	31	ability	ability	NN
cord-010570-ytv7dwr0	159	32	to	to	TO
cord-010570-ytv7dwr0	159	33	either	either	CC
cord-010570-ytv7dwr0	159	34	cross	cross	VB
cord-010570-ytv7dwr0	159	35	the	the	DT
cord-010570-ytv7dwr0	159	36	placenta	placenta	NN
cord-010570-ytv7dwr0	159	37	to	to	TO
cord-010570-ytv7dwr0	159	38	provide	provide	VB
cord-010570-ytv7dwr0	159	39	antibody	antibody	NN
cord-010570-ytv7dwr0	159	40	protection	protection	NN
cord-010570-ytv7dwr0	159	41	to	to	IN
cord-010570-ytv7dwr0	159	42	fetuses	fetus	NNS
cord-010570-ytv7dwr0	159	43	and	and	CC
cord-010570-ytv7dwr0	159	44	newborns	newborn	NNS
cord-010570-ytv7dwr0	159	45	[	[	-LRB-
cord-010570-ytv7dwr0	159	46	113	113	CD
cord-010570-ytv7dwr0	159	47	]	]	-RRB-
cord-010570-ytv7dwr0	159	48	or	or	CC
cord-010570-ytv7dwr0	159	49	to	to	TO
cord-010570-ytv7dwr0	159	50	be	be	VB
cord-010570-ytv7dwr0	159	51	excluded	exclude	VBN
cord-010570-ytv7dwr0	159	52	from	from	IN
cord-010570-ytv7dwr0	159	53	the	the	DT
cord-010570-ytv7dwr0	159	54	placenta	placenta	NN
cord-010570-ytv7dwr0	159	55	if	if	IN
cord-010570-ytv7dwr0	159	56	fetal	fetal	JJ
cord-010570-ytv7dwr0	159	57	toxicity	toxicity	NN
cord-010570-ytv7dwr0	159	58	is	be	VBZ
cord-010570-ytv7dwr0	159	59	a	a	DT
cord-010570-ytv7dwr0	159	60	concern	concern	NN
cord-010570-ytv7dwr0	159	61	.	.	.
cord-010570-ytv7dwr0	160	1	Heterologous	Heterologous	NNP
cord-010570-ytv7dwr0	160	2	mAbs	mAbs	NNP
cord-010570-ytv7dwr0	160	3	(	(	-LRB-
cord-010570-ytv7dwr0	160	4	i.e.	i.e.	FW
cord-010570-ytv7dwr0	160	5	,	,	,
cord-010570-ytv7dwr0	160	6	murine	murine	JJ
cord-010570-ytv7dwr0	160	7	mAbs	mAbs	NNP
cord-010570-ytv7dwr0	160	8	)	)	-RRB-
cord-010570-ytv7dwr0	160	9	have	have	VBP
cord-010570-ytv7dwr0	160	10	shorter	short	JJR
cord-010570-ytv7dwr0	160	11	half	half	RB
cord-010570-ytv7dwr0	160	12	-	-	HYPH
cord-010570-ytv7dwr0	160	13	lives	life	NNS
cord-010570-ytv7dwr0	160	14	in	in	IN
cord-010570-ytv7dwr0	160	15	humans	human	NNS
cord-010570-ytv7dwr0	160	16	,	,	,
cord-010570-ytv7dwr0	160	17	but	but	CC
cord-010570-ytv7dwr0	161	1	chimeric	chimeric	JJ
cord-010570-ytv7dwr0	161	2	and	and	CC
cord-010570-ytv7dwr0	161	3	humanized	humanized	JJ
cord-010570-ytv7dwr0	161	4	mAbs	mAbs	NNP
cord-010570-ytv7dwr0	161	5	have	have	VB
cord-010570-ytv7dwr0	161	6	longer	long	JJR
cord-010570-ytv7dwr0	161	7	half	half	RB
cord-010570-ytv7dwr0	161	8	-	-	HYPH
cord-010570-ytv7dwr0	161	9	lives	life	NNS
cord-010570-ytv7dwr0	161	10	than	than	IN
cord-010570-ytv7dwr0	161	11	their	-PRON-	PRP$
cord-010570-ytv7dwr0	161	12	murine	murine	JJ
cord-010570-ytv7dwr0	161	13	precursors	precursor	NNS
cord-010570-ytv7dwr0	161	14	.	.	.
cord-010570-ytv7dwr0	162	1	mAbs	mabs	NN
cord-010570-ytv7dwr0	162	2	with	with	IN
cord-010570-ytv7dwr0	162	3	a	a	DT
cord-010570-ytv7dwr0	162	4	longer	long	JJR
cord-010570-ytv7dwr0	162	5	half	half	JJ
cord-010570-ytv7dwr0	162	6	-	-	HYPH
cord-010570-ytv7dwr0	162	7	life	life	NN
cord-010570-ytv7dwr0	162	8	can	can	MD
cord-010570-ytv7dwr0	162	9	,	,	,
cord-010570-ytv7dwr0	162	10	in	in	IN
cord-010570-ytv7dwr0	162	11	principle	principle	NN
cord-010570-ytv7dwr0	162	12	,	,	,
cord-010570-ytv7dwr0	162	13	be	be	VB
cord-010570-ytv7dwr0	162	14	engineered	engineer	VBN
cord-010570-ytv7dwr0	162	15	by	by	IN
cord-010570-ytv7dwr0	162	16	altering	alter	VBG
cord-010570-ytv7dwr0	162	17	the	the	DT
cord-010570-ytv7dwr0	162	18	regions	region	NNS
cord-010570-ytv7dwr0	162	19	of	of	IN
cord-010570-ytv7dwr0	162	20	the	the	DT
cord-010570-ytv7dwr0	162	21	constant	constant	JJ
cord-010570-ytv7dwr0	162	22	domain	domain	NN
cord-010570-ytv7dwr0	162	23	that	that	WDT
cord-010570-ytv7dwr0	162	24	regulate	regulate	VBP
cord-010570-ytv7dwr0	162	25	clearance	clearance	NN
cord-010570-ytv7dwr0	162	26	.	.	.
cord-010570-ytv7dwr0	163	1	A	a	DT
cord-010570-ytv7dwr0	163	2	disadvantage	disadvantage	NN
cord-010570-ytv7dwr0	163	3	of	of	IN
cord-010570-ytv7dwr0	163	4	antibody	antibody	NN
cord-010570-ytv7dwr0	163	5	-	-	HYPH
cord-010570-ytv7dwr0	163	6	based	base	VBN
cord-010570-ytv7dwr0	163	7	therapies	therapy	NNS
cord-010570-ytv7dwr0	163	8	is	be	VBZ
cord-010570-ytv7dwr0	163	9	the	the	DT
cord-010570-ytv7dwr0	163	10	need	need	NN
cord-010570-ytv7dwr0	163	11	for	for	IN
cord-010570-ytv7dwr0	163	12	systemic	systemic	JJ
cord-010570-ytv7dwr0	163	13	administration	administration	NN
cord-010570-ytv7dwr0	163	14	.	.	.
cord-010570-ytv7dwr0	164	1	Oral	oral	JJ
cord-010570-ytv7dwr0	164	2	administration	administration	NN
cord-010570-ytv7dwr0	164	3	is	be	VBZ
cord-010570-ytv7dwr0	164	4	unlikely	unlikely	JJ
cord-010570-ytv7dwr0	164	5	to	to	TO
cord-010570-ytv7dwr0	164	6	be	be	VB
cord-010570-ytv7dwr0	164	7	effective	effective	JJ
cord-010570-ytv7dwr0	164	8	,	,	,
cord-010570-ytv7dwr0	164	9	with	with	IN
cord-010570-ytv7dwr0	164	10	the	the	DT
cord-010570-ytv7dwr0	164	11	possible	possible	JJ
cord-010570-ytv7dwr0	164	12	exception	exception	NN
cord-010570-ytv7dwr0	164	13	of	of	IN
cord-010570-ytv7dwr0	164	14	therapy	therapy	NN
cord-010570-ytv7dwr0	164	15	for	for	IN
cord-010570-ytv7dwr0	164	16	enteric	enteric	JJ
cord-010570-ytv7dwr0	164	17	pathogens	pathogen	NNS
cord-010570-ytv7dwr0	164	18	[	[	-LRB-
cord-010570-ytv7dwr0	164	19	73	73	CD
cord-010570-ytv7dwr0	164	20	,	,	,
cord-010570-ytv7dwr0	164	21	114	114	CD
cord-010570-ytv7dwr0	164	22	]	]	-RRB-
cord-010570-ytv7dwr0	164	23	.	.	.
cord-010570-ytv7dwr0	165	1	The	the	DT
cord-010570-ytv7dwr0	165	2	blood	blood	NN
cord-010570-ytv7dwr0	165	3	-	-	HYPH
cord-010570-ytv7dwr0	165	4	brain	brain	NN
cord-010570-ytv7dwr0	165	5	barrier	barrier	NN
cord-010570-ytv7dwr0	165	6	is	be	VBZ
cord-010570-ytv7dwr0	165	7	a	a	DT
cord-010570-ytv7dwr0	165	8	potential	potential	JJ
cord-010570-ytv7dwr0	165	9	obstacle	obstacle	NN
cord-010570-ytv7dwr0	165	10	for	for	IN
cord-010570-ytv7dwr0	165	11	antibody	antibody	NN
cord-010570-ytv7dwr0	165	12	therapy	therapy	NN
cord-010570-ytv7dwr0	165	13	for	for	IN
cord-010570-ytv7dwr0	165	14	infections	infection	NNS
cord-010570-ytv7dwr0	165	15	of	of	IN
cord-010570-ytv7dwr0	165	16	the	the	DT
cord-010570-ytv7dwr0	165	17	brain	brain	NN
cord-010570-ytv7dwr0	165	18	.	.	.
cord-010570-ytv7dwr0	166	1	However	however	RB
cord-010570-ytv7dwr0	166	2	,	,	,
cord-010570-ytv7dwr0	166	3	in	in	IN
cord-010570-ytv7dwr0	166	4	infections	infection	NNS
cord-010570-ytv7dwr0	166	5	of	of	IN
cord-010570-ytv7dwr0	166	6	the	the	DT
cord-010570-ytv7dwr0	166	7	brain	brain	NN
cord-010570-ytv7dwr0	166	8	in	in	IN
cord-010570-ytv7dwr0	166	9	which	which	WDT
cord-010570-ytv7dwr0	166	10	there	there	EX
cord-010570-ytv7dwr0	166	11	is	be	VBZ
cord-010570-ytv7dwr0	166	12	inflammation	inflammation	NN
cord-010570-ytv7dwr0	166	13	,	,	,
cord-010570-ytv7dwr0	166	14	there	there	EX
cord-010570-ytv7dwr0	166	15	is	be	VBZ
cord-010570-ytv7dwr0	166	16	increased	increase	VBN
cord-010570-ytv7dwr0	166	17	antibody	antibody	NN
cord-010570-ytv7dwr0	166	18	penetration	penetration	NN
cord-010570-ytv7dwr0	166	19	,	,	,
cord-010570-ytv7dwr0	166	20	and	and	CC
cord-010570-ytv7dwr0	166	21	intravenous	intravenous	JJ
cord-010570-ytv7dwr0	166	22	administration	administration	NN
cord-010570-ytv7dwr0	166	23	of	of	IN
cord-010570-ytv7dwr0	166	24	antibodies	antibody	NNS
cord-010570-ytv7dwr0	166	25	appears	appear	VBZ
cord-010570-ytv7dwr0	166	26	to	to	TO
cord-010570-ytv7dwr0	166	27	have	have	VB
cord-010570-ytv7dwr0	166	28	been	be	VBN
cord-010570-ytv7dwr0	166	29	successfully	successfully	RB
cord-010570-ytv7dwr0	166	30	used	use	VBN
cord-010570-ytv7dwr0	166	31	for	for	IN
cord-010570-ytv7dwr0	166	32	therapy	therapy	NN
cord-010570-ytv7dwr0	166	33	of	of	IN
cord-010570-ytv7dwr0	166	34	meningococcal	meningococcal	JJ
cord-010570-ytv7dwr0	166	35	meningitis	meningitis	NN
cord-010570-ytv7dwr0	166	36	[	[	-LRB-
cord-010570-ytv7dwr0	166	37	115	115	CD
cord-010570-ytv7dwr0	166	38	]	]	-RRB-
cord-010570-ytv7dwr0	166	39	.	.	.
cord-010570-ytv7dwr0	167	1	Antibodybased	antibodybased	JJ
cord-010570-ytv7dwr0	167	2	therapies	therapy	NNS
cord-010570-ytv7dwr0	167	3	can	can	MD
cord-010570-ytv7dwr0	167	4	also	also	RB
cord-010570-ytv7dwr0	167	5	be	be	VB
cord-010570-ytv7dwr0	167	6	administered	administer	VBN
cord-010570-ytv7dwr0	167	7	directly	directly	RB
cord-010570-ytv7dwr0	167	8	into	into	IN
cord-010570-ytv7dwr0	167	9	the	the	DT
cord-010570-ytv7dwr0	167	10	subarachnoid	subarachnoid	NN
cord-010570-ytv7dwr0	167	11	space	space	NN
cord-010570-ytv7dwr0	167	12	,	,	,
cord-010570-ytv7dwr0	167	13	as	as	IN
cord-010570-ytv7dwr0	167	14	has	have	VBZ
cord-010570-ytv7dwr0	167	15	been	be	VBN
cord-010570-ytv7dwr0	167	16	done	do	VBN
cord-010570-ytv7dwr0	167	17	for	for	IN
cord-010570-ytv7dwr0	167	18	the	the	DT
cord-010570-ytv7dwr0	167	19	treatment	treatment	NN
cord-010570-ytv7dwr0	167	20	ofmeningococcal	ofmeningococcal	JJ
cord-010570-ytv7dwr0	167	21	and	and	CC
cord-010570-ytv7dwr0	167	22	H.	H.	NNP
cord-010570-ytv7dwr0	167	23	influenzae	influenzae	NN
cord-010570-ytv7dwr0	167	24	meningitis	meningitis	NN
cord-010570-ytv7dwr0	167	25	[	[	-LRB-
cord-010570-ytv7dwr0	167	26	8	8	CD
cord-010570-ytv7dwr0	167	27	,	,	,
cord-010570-ytv7dwr0	167	28	38	38	CD
cord-010570-ytv7dwr0	167	29	]	]	-RRB-
cord-010570-ytv7dwr0	167	30	.	.	.
cord-010570-ytv7dwr0	168	1	Enhanced	enhanced	JJ
cord-010570-ytv7dwr0	168	2	penetration	penetration	NN
cord-010570-ytv7dwr0	168	3	of	of	IN
cord-010570-ytv7dwr0	168	4	the	the	DT
cord-010570-ytv7dwr0	168	5	brain	brain	NN
cord-010570-ytv7dwr0	168	6	can	can	MD
cord-010570-ytv7dwr0	168	7	be	be	VB
cord-010570-ytv7dwr0	168	8	achieved	achieve	VBN
cord-010570-ytv7dwr0	168	9	by	by	IN
cord-010570-ytv7dwr0	168	10	modifying	modify	VBG
cord-010570-ytv7dwr0	168	11	the	the	DT
cord-010570-ytv7dwr0	168	12	charge	charge	NN
cord-010570-ytv7dwr0	168	13	of	of	IN
cord-010570-ytv7dwr0	168	14	the	the	DT
cord-010570-ytv7dwr0	168	15	molecule	molecule	NN
cord-010570-ytv7dwr0	168	16	[	[	-LRB-
cord-010570-ytv7dwr0	168	17	116	116	CD
cord-010570-ytv7dwr0	168	18	]	]	-RRB-
cord-010570-ytv7dwr0	168	19	or	or	CC
cord-010570-ytv7dwr0	168	20	by	by	IN
cord-010570-ytv7dwr0	168	21	linking	link	VBG
cord-010570-ytv7dwr0	168	22	it	-PRON-	PRP
cord-010570-ytv7dwr0	168	23	to	to	TO
cord-010570-ytv7dwr0	168	24	carrier	carrier	NN
cord-010570-ytv7dwr0	168	25	proteins	protein	NNS
cord-010570-ytv7dwr0	168	26	that	that	WDT
cord-010570-ytv7dwr0	168	27	cross	cross	VBP
cord-010570-ytv7dwr0	168	28	the	the	DT
cord-010570-ytv7dwr0	168	29	blood	blood	NN
cord-010570-ytv7dwr0	168	30	-	-	HYPH
cord-010570-ytv7dwr0	168	31	brain	brain	NN
cord-010570-ytv7dwr0	168	32	barrier	barrier	NN
cord-010570-ytv7dwr0	168	33	[	[	-LRB-
cord-010570-ytv7dwr0	168	34	117	117	CD
cord-010570-ytv7dwr0	168	35	]	]	-RRB-
cord-010570-ytv7dwr0	168	36	.	.	.
cord-010570-ytv7dwr0	169	1	Antibody	antibody	NN
cord-010570-ytv7dwr0	169	2	therapy	therapy	NN
cord-010570-ytv7dwr0	169	3	for	for	IN
cord-010570-ytv7dwr0	169	4	brain	brain	NN
cord-010570-ytv7dwr0	169	5	infections	infection	NNS
cord-010570-ytv7dwr0	169	6	may	may	MD
cord-010570-ytv7dwr0	169	7	be	be	VB
cord-010570-ytv7dwr0	169	8	feasible	feasible	JJ
cord-010570-ytv7dwr0	169	9	if	if	IN
cord-010570-ytv7dwr0	169	10	the	the	DT
cord-010570-ytv7dwr0	169	11	blood	blood	NN
cord-010570-ytv7dwr0	169	12	-	-	HYPH
cord-010570-ytv7dwr0	169	13	brain	brain	NN
cord-010570-ytv7dwr0	169	14	barrier	barrier	NN
cord-010570-ytv7dwr0	169	15	is	be	VBZ
cord-010570-ytv7dwr0	169	16	leaky	leaky	JJ
cord-010570-ytv7dwr0	169	17	,	,	,
cord-010570-ytv7dwr0	169	18	if	if	IN
cord-010570-ytv7dwr0	169	19	antibody	antibody	NN
cord-010570-ytv7dwr0	169	20	is	be	VBZ
cord-010570-ytv7dwr0	169	21	administered	administer	VBN
cord-010570-ytv7dwr0	169	22	directly	directly	RB
cord-010570-ytv7dwr0	169	23	into	into	IN
cord-010570-ytv7dwr0	169	24	the	the	DT
cord-010570-ytv7dwr0	169	25	subarachnoid	subarachnoid	NN
cord-010570-ytv7dwr0	169	26	space	space	NN
cord-010570-ytv7dwr0	169	27	,	,	,
cord-010570-ytv7dwr0	169	28	or	or	CC
cord-010570-ytv7dwr0	169	29	if	if	IN
cord-010570-ytv7dwr0	169	30	antibodies	antibody	NNS
cord-010570-ytv7dwr0	169	31	with	with	IN
cord-010570-ytv7dwr0	169	32	greater	great	JJR
cord-010570-ytv7dwr0	169	33	brain	brain	NN
cord-010570-ytv7dwr0	169	34	penetration	penetration	NN
cord-010570-ytv7dwr0	169	35	are	be	VBP
cord-010570-ytv7dwr0	169	36	used	use	VBN
cord-010570-ytv7dwr0	169	37	.	.	.
cord-010570-ytv7dwr0	170	1	Additional	additional	JJ
cord-010570-ytv7dwr0	170	2	research	research	NN
cord-010570-ytv7dwr0	170	3	into	into	IN
cord-010570-ytv7dwr0	170	4	the	the	DT
cord-010570-ytv7dwr0	170	5	pharmacokinetics	pharmacokinetic	NNS
cord-010570-ytv7dwr0	170	6	of	of	IN
cord-010570-ytv7dwr0	170	7	antibodies	antibody	NNS
cord-010570-ytv7dwr0	170	8	in	in	IN
cord-010570-ytv7dwr0	170	9	infection	infection	NN
cord-010570-ytv7dwr0	170	10	is	be	VBZ
cord-010570-ytv7dwr0	170	11	likely	likely	JJ
cord-010570-ytv7dwr0	170	12	to	to	TO
cord-010570-ytv7dwr0	170	13	be	be	VB
cord-010570-ytv7dwr0	170	14	required	require	VBN
cord-010570-ytv7dwr0	170	15	for	for	IN
cord-010570-ytv7dwr0	170	16	optimal	optimal	JJ
cord-010570-ytv7dwr0	170	17	use	use	NN
cord-010570-ytv7dwr0	170	18	of	of	IN
cord-010570-ytv7dwr0	170	19	antibody	antibody	NN
cord-010570-ytv7dwr0	170	20	-	-	HYPH
cord-010570-ytv7dwr0	170	21	based	base	VBN
cord-010570-ytv7dwr0	170	22	therapies	therapy	NNS
cord-010570-ytv7dwr0	170	23	.	.	.
cord-010570-ytv7dwr0	171	1	Studies	study	NNS
cord-010570-ytv7dwr0	171	2	of	of	IN
cord-010570-ytv7dwr0	171	3	antibody	antibody	NN
cord-010570-ytv7dwr0	171	4	binding	bind	VBG
cord-010570-ytv7dwr0	171	5	to	to	IN
cord-010570-ytv7dwr0	171	6	tumors	tumor	NNS
cord-010570-ytv7dwr0	171	7	have	have	VBP
cord-010570-ytv7dwr0	171	8	revealed	reveal	VBN
cord-010570-ytv7dwr0	171	9	complex	complex	JJ
cord-010570-ytv7dwr0	171	10	pharmacokinetics	pharmacokinetic	NNS
cord-010570-ytv7dwr0	171	11	[	[	-LRB-
cord-010570-ytv7dwr0	171	12	112	112	CD
cord-010570-ytv7dwr0	171	13	]	]	-RRB-
cord-010570-ytv7dwr0	171	14	.	.	.
cord-010570-ytv7dwr0	172	1	There	there	EX
cord-010570-ytv7dwr0	172	2	may	may	MD
cord-010570-ytv7dwr0	172	3	be	be	VB
cord-010570-ytv7dwr0	172	4	problems	problem	NNS
cord-010570-ytv7dwr0	172	5	with	with	IN
cord-010570-ytv7dwr0	172	6	antibody	antibody	NN
cord-010570-ytv7dwr0	172	7	penetration	penetration	NN
cord-010570-ytv7dwr0	172	8	into	into	IN
cord-010570-ytv7dwr0	172	9	abscesses	abscess	NNS
cord-010570-ytv7dwr0	172	10	as	as	IN
cord-010570-ytv7dwr0	172	11	have	have	VBP
cord-010570-ytv7dwr0	172	12	been	be	VBN
cord-010570-ytv7dwr0	172	13	found	find	VBN
cord-010570-ytv7dwr0	172	14	with	with	IN
cord-010570-ytv7dwr0	172	15	tumors	tumor	NNS
cord-010570-ytv7dwr0	172	16	.	.	.
cord-010570-ytv7dwr0	173	1	Toxicity	toxicity	NN
cord-010570-ytv7dwr0	173	2	.	.	.
cord-010570-ytv7dwr0	174	1	Immunoglobulins	immunoglobulin	NNS
cord-010570-ytv7dwr0	174	2	are	be	VBP
cord-010570-ytv7dwr0	174	3	generally	generally	RB
cord-010570-ytv7dwr0	174	4	safe	safe	JJ
cord-010570-ytv7dwr0	174	5	drugs	drug	NNS
cord-010570-ytv7dwr0	174	6	[	[	-LRB-
cord-010570-ytv7dwr0	174	7	67	67	CD
cord-010570-ytv7dwr0	174	8	]	]	-RRB-
cord-010570-ytv7dwr0	174	9	.	.	.
cord-010570-ytv7dwr0	175	1	Nevertheless	nevertheless	RB
cord-010570-ytv7dwr0	175	2	,	,	,
cord-010570-ytv7dwr0	175	3	serious	serious	JJ
cord-010570-ytv7dwr0	175	4	side	side	NN
cord-010570-ytv7dwr0	175	5	effects	effect	NNS
cord-010570-ytv7dwr0	175	6	have	have	VBP
cord-010570-ytv7dwr0	175	7	been	be	VBN
cord-010570-ytv7dwr0	175	8	reported	report	VBN
cord-010570-ytv7dwr0	175	9	with	with	IN
cord-010570-ytv7dwr0	175	10	highdose	highdose	NN
cord-010570-ytv7dwr0	175	11	(	(	-LRB-
cord-010570-ytv7dwr0	175	12	0.5	0.5	CD
cord-010570-ytv7dwr0	175	13	-	-	SYM
cord-010570-ytv7dwr0	175	14	2	2	CD
cord-010570-ytv7dwr0	175	15	g	g	NN
cord-010570-ytv7dwr0	175	16	/	/	SYM
cord-010570-ytv7dwr0	175	17	kg	kg	NN
cord-010570-ytv7dwr0	175	18	)	)	-RRB-
cord-010570-ytv7dwr0	175	19	antibody	antibody	NN
cord-010570-ytv7dwr0	175	20	therapy	therapy	NN
cord-010570-ytv7dwr0	175	21	,	,	,
cord-010570-ytv7dwr0	175	22	including	include	VBG
cord-010570-ytv7dwr0	175	23	rare	rare	JJ
cord-010570-ytv7dwr0	175	24	cases	case	NNS
cord-010570-ytv7dwr0	175	25	of	of	IN
cord-010570-ytv7dwr0	175	26	renal	renal	JJ
cord-010570-ytv7dwr0	175	27	failure	failure	NN
cord-010570-ytv7dwr0	175	28	[	[	-LRB-
cord-010570-ytv7dwr0	175	29	118	118	CD
cord-010570-ytv7dwr0	175	30	]	]	-RRB-
cord-010570-ytv7dwr0	175	31	,	,	,
cord-010570-ytv7dwr0	175	32	aseptic	aseptic	JJ
cord-010570-ytv7dwr0	175	33	meningitis	meningitis	NN
cord-010570-ytv7dwr0	175	34	[	[	-LRB-
cord-010570-ytv7dwr0	175	35	119	119	CD
cord-010570-ytv7dwr0	175	36	]	]	-RRB-
cord-010570-ytv7dwr0	175	37	,	,	,
cord-010570-ytv7dwr0	175	38	and	and	CC
cord-010570-ytv7dwr0	175	39	thromboembolic	thromboembolic	JJ
cord-010570-ytv7dwr0	175	40	events	event	NNS
cord-010570-ytv7dwr0	175	41	[	[	-LRB-
cord-010570-ytv7dwr0	175	42	120	120	CD
cord-010570-ytv7dwr0	175	43	,	,	,
cord-010570-ytv7dwr0	175	44	121	121	CD
cord-010570-ytv7dwr0	175	45	]	]	-RRB-
cord-010570-ytv7dwr0	175	46	.	.	.
cord-010570-ytv7dwr0	176	1	High	high	JJ
cord-010570-ytv7dwr0	176	2	-	-	HYPH
cord-010570-ytv7dwr0	176	3	dose	dose	NN
cord-010570-ytv7dwr0	176	4	immunoglobulin	immunoglobulin	NN
cord-010570-ytv7dwr0	176	5	therapy	therapy	NN
cord-010570-ytv7dwr0	176	6	is	be	VBZ
cord-010570-ytv7dwr0	176	7	unlikely	unlikely	JJ
cord-010570-ytv7dwr0	176	8	to	to	TO
cord-010570-ytv7dwr0	176	9	be	be	VB
cord-010570-ytv7dwr0	176	10	required	require	VBN
cord-010570-ytv7dwr0	176	11	in	in	IN
cord-010570-ytv7dwr0	176	12	antiinfective	antiinfective	JJ
cord-010570-ytv7dwr0	176	13	mAb	mab	NN
cord-010570-ytv7dwr0	176	14	therapy	therapy	NN
cord-010570-ytv7dwr0	176	15	.	.	.
cord-010570-ytv7dwr0	177	1	In	in	IN
cord-010570-ytv7dwr0	177	2	the	the	DT
cord-010570-ytv7dwr0	177	3	past	past	NN
cord-010570-ytv7dwr0	177	4	,	,	,
cord-010570-ytv7dwr0	177	5	serum	serum	NN
cord-010570-ytv7dwr0	177	6	therapy	therapy	NN
cord-010570-ytv7dwr0	177	7	was	be	VBD
cord-010570-ytv7dwr0	177	8	effective	effective	JJ
cord-010570-ytv7dwr0	177	9	against	against	IN
cord-010570-ytv7dwr0	177	10	various	various	JJ
cord-010570-ytv7dwr0	177	11	pathogens	pathogen	NNS
cord-010570-ytv7dwr0	177	12	despite	despite	IN
cord-010570-ytv7dwr0	177	13	the	the	DT
cord-010570-ytv7dwr0	177	14	fact	fact	NN
cord-010570-ytv7dwr0	177	15	that	that	IN
cord-010570-ytv7dwr0	177	16	immune	immune	JJ
cord-010570-ytv7dwr0	177	17	sera	sera	NNP
cord-010570-ytv7dwr0	177	18	contained	contain	VBD
cord-010570-ytv7dwr0	177	19	only	only	RB
cord-010570-ytv7dwr0	177	20	small	small	JJ
cord-010570-ytv7dwr0	177	21	amounts	amount	NNS
cord-010570-ytv7dwr0	177	22	of	of	IN
cord-010570-ytv7dwr0	177	23	specific	specific	JJ
cord-010570-ytv7dwr0	177	24	antibody	antibody	NN
cord-010570-ytv7dwr0	177	25	.	.	.
cord-010570-ytv7dwr0	178	1	mAbs	mabs	NN
cord-010570-ytv7dwr0	178	2	have	have	VBP
cord-010570-ytv7dwr0	178	3	significantly	significantly	RB
cord-010570-ytv7dwr0	178	4	higher	high	JJR
cord-010570-ytv7dwr0	178	5	specific	specific	JJ
cord-010570-ytv7dwr0	178	6	activity	activity	NN
cord-010570-ytv7dwr0	178	7	than	than	IN
cord-010570-ytv7dwr0	178	8	polyclonal	polyclonal	JJ
cord-010570-ytv7dwr0	178	9	preparations	preparation	NNS
cord-010570-ytv7dwr0	178	10	.	.	.
cord-010570-ytv7dwr0	179	1	For	for	IN
cord-010570-ytv7dwr0	179	2	example	example	NN
cord-010570-ytv7dwr0	179	3	,	,	,
cord-010570-ytv7dwr0	179	4	0.7	0.7	CD
cord-010570-ytv7dwr0	179	5	mg	mg	CD
cord-010570-ytv7dwr0	179	6	of	of	IN
cord-010570-ytv7dwr0	179	7	two	two	CD
cord-010570-ytv7dwr0	179	8	anti	anti	JJ
cord-010570-ytv7dwr0	179	9	-	-	JJ
cord-010570-ytv7dwr0	179	10	tetanus	tetanus	JJ
cord-010570-ytv7dwr0	179	11	toxin	toxin	NN
cord-010570-ytv7dwr0	179	12	human	human	JJ
cord-010570-ytv7dwr0	179	13	mAbs	mAbs	NNP
cord-010570-ytv7dwr0	179	14	provides	provide	VBZ
cord-010570-ytv7dwr0	179	15	the	the	DT
cord-010570-ytv7dwr0	179	16	same	same	JJ
cord-010570-ytv7dwr0	179	17	activity	activity	NN
cord-010570-ytv7dwr0	179	18	as	as	IN
cord-010570-ytv7dwr0	179	19	100	100	CD
cord-010570-ytv7dwr0	179	20	-	-	SYM
cord-010570-ytv7dwr0	179	21	170	170	CD
cord-010570-ytv7dwr0	179	22	mg	mg	NNS
cord-010570-ytv7dwr0	179	23	of	of	IN
cord-010570-ytv7dwr0	179	24	immune	immune	JJ
cord-010570-ytv7dwr0	179	25	globulin	globulin	NN
cord-010570-ytv7dwr0	179	26	[	[	-LRB-
cord-010570-ytv7dwr0	179	27	122	122	CD
cord-010570-ytv7dwr0	179	28	]	]	-RRB-
cord-010570-ytv7dwr0	179	29	.	.	.
cord-010570-ytv7dwr0	180	1	Thus	thus	RB
cord-010570-ytv7dwr0	180	2	,	,	,
cord-010570-ytv7dwr0	180	3	the	the	DT
cord-010570-ytv7dwr0	180	4	toxicities	toxicity	NNS
cord-010570-ytv7dwr0	180	5	described	describe	VBN
cord-010570-ytv7dwr0	180	6	for	for	IN
cord-010570-ytv7dwr0	180	7	high	high	JJ
cord-010570-ytv7dwr0	180	8	-	-	HYPH
cord-010570-ytv7dwr0	180	9	dose	dose	NN
cord-010570-ytv7dwr0	180	10	immunoglobulin	immunoglobulin	NN
cord-010570-ytv7dwr0	180	11	therapy	therapy	NN
cord-010570-ytv7dwr0	180	12	may	may	MD
cord-010570-ytv7dwr0	180	13	not	not	RB
cord-010570-ytv7dwr0	180	14	be	be	VB
cord-010570-ytv7dwr0	180	15	relevant	relevant	JJ
cord-010570-ytv7dwr0	180	16	in	in	IN
cord-010570-ytv7dwr0	180	17	antiinfective	antiinfective	JJ
cord-010570-ytv7dwr0	180	18	therapies	therapy	NNS
cord-010570-ytv7dwr0	180	19	with	with	IN
cord-010570-ytv7dwr0	180	20	mAbs	mAbs	NNP
cord-010570-ytv7dwr0	180	21	.	.	.
cord-010570-ytv7dwr0	181	1	Until	until	IN
cord-010570-ytv7dwr0	181	2	fully	fully	RB
cord-010570-ytv7dwr0	181	3	human	human	JJ
cord-010570-ytv7dwr0	181	4	mAbs	mabs	NN
cord-010570-ytv7dwr0	181	5	are	be	VBP
cord-010570-ytv7dwr0	181	6	available	available	JJ
cord-010570-ytv7dwr0	181	7	,	,	,
cord-010570-ytv7dwr0	181	8	rodent	rodent	NN
cord-010570-ytv7dwr0	181	9	,	,	,
cord-010570-ytv7dwr0	181	10	mousehuman	mousehuman	NN
cord-010570-ytv7dwr0	181	11	chimeric	chimeric	JJ
cord-010570-ytv7dwr0	181	12	,	,	,
cord-010570-ytv7dwr0	181	13	or	or	CC
cord-010570-ytv7dwr0	181	14	humanized	humanize	VBN
cord-010570-ytv7dwr0	181	15	mAbs	mAbs	NNP
cord-010570-ytv7dwr0	181	16	are	be	VBP
cord-010570-ytv7dwr0	181	17	therapeutic	therapeutic	JJ
cord-010570-ytv7dwr0	181	18	options	option	NNS
cord-010570-ytv7dwr0	181	19	.	.	.
cord-010570-ytv7dwr0	182	1	For	for	IN
cord-010570-ytv7dwr0	182	2	over	over	IN
cord-010570-ytv7dwr0	182	3	a	a	DT
cord-010570-ytv7dwr0	182	4	decade	decade	NN
cord-010570-ytv7dwr0	182	5	,	,	,
cord-010570-ytv7dwr0	182	6	murine	murine	JJ
cord-010570-ytv7dwr0	182	7	mAbs	mAbs	NNP
cord-010570-ytv7dwr0	182	8	directed	direct	VBN
cord-010570-ytv7dwr0	182	9	against	against	IN
cord-010570-ytv7dwr0	182	10	T	T	NNP
cord-010570-ytv7dwr0	182	11	cells	cell	NNS
cord-010570-ytv7dwr0	182	12	have	have	VBP
cord-010570-ytv7dwr0	182	13	been	be	VBN
cord-010570-ytv7dwr0	182	14	used	use	VBN
cord-010570-ytv7dwr0	182	15	to	to	TO
cord-010570-ytv7dwr0	182	16	prevent	prevent	VB
cord-010570-ytv7dwr0	182	17	organ	organ	NN
cord-010570-ytv7dwr0	182	18	graft	graft	NN
cord-010570-ytv7dwr0	182	19	rejection	rejection	NN
cord-010570-ytv7dwr0	182	20	in	in	IN
cord-010570-ytv7dwr0	182	21	humans	human	NNS
cord-010570-ytv7dwr0	182	22	[	[	-LRB-
cord-010570-ytv7dwr0	182	23	92	92	CD
cord-010570-ytv7dwr0	182	24	]	]	-RRB-
cord-010570-ytv7dwr0	182	25	.	.	.
cord-010570-ytv7dwr0	183	1	A	a	DT
cord-010570-ytv7dwr0	183	2	murine	murine	JJ
cord-010570-ytv7dwr0	183	3	IgM	igm	NN
cord-010570-ytv7dwr0	183	4	to	to	TO
cord-010570-ytv7dwr0	183	5	endotoxin	endotoxin	NN
cord-010570-ytv7dwr0	183	6	(	(	-LRB-
cord-010570-ytv7dwr0	183	7	E5	E5	NNP
cord-010570-ytv7dwr0	183	8	)	)	-RRB-
cord-010570-ytv7dwr0	183	9	was	be	VBD
cord-010570-ytv7dwr0	183	10	tested	test	VBN
cord-010570-ytv7dwr0	183	11	in	in	IN
cord-010570-ytv7dwr0	183	12	247	247	CD
cord-010570-ytv7dwr0	183	13	patients	patient	NNS
cord-010570-ytv7dwr0	183	14	with	with	IN
cord-010570-ytv7dwr0	183	15	sepsis	sepsis	NN
cord-010570-ytv7dwr0	183	16	and	and	CC
cord-010570-ytv7dwr0	183	17	appeared	appear	VBD
cord-010570-ytv7dwr0	183	18	to	to	TO
cord-010570-ytv7dwr0	183	19	be	be	VB
cord-010570-ytv7dwr0	183	20	a	a	DT
cord-010570-ytv7dwr0	183	21	safe	safe	JJ
cord-010570-ytv7dwr0	183	22	treatment	treatment	NN
cord-010570-ytv7dwr0	183	23	[	[	-LRB-
cord-010570-ytv7dwr0	183	24	123	123	CD
cord-010570-ytv7dwr0	183	25	]	]	-RRB-
cord-010570-ytv7dwr0	183	26	.	.	.
cord-010570-ytv7dwr0	184	1	Although	although	IN
cord-010570-ytv7dwr0	184	2	administration	administration	NN
cord-010570-ytv7dwr0	184	3	of	of	IN
cord-010570-ytv7dwr0	184	4	murine	murine	NNP
cord-010570-ytv7dwr0	184	5	mAbs	mAbs	NNP
cord-010570-ytv7dwr0	184	6	is	be	VBZ
cord-010570-ytv7dwr0	184	7	generally	generally	RB
cord-010570-ytv7dwr0	184	8	well	well	RB
cord-010570-ytv7dwr0	184	9	tolerated	tolerate	VBN
cord-010570-ytv7dwr0	184	10	in	in	IN
cord-010570-ytv7dwr0	184	11	humans	human	NNS
cord-010570-ytv7dwr0	184	12	,	,	,
cord-010570-ytv7dwr0	184	13	allergic	allergic	JJ
cord-010570-ytv7dwr0	184	14	reactions	reaction	NNS
cord-010570-ytv7dwr0	184	15	occur	occur	VBP
cord-010570-ytv7dwr0	184	16	in	in	IN
cord-010570-ytv7dwr0	184	17	1%-2	1%-2	CD
cord-010570-ytv7dwr0	184	18	%	%	NN
cord-010570-ytv7dwr0	184	19	of	of	IN
cord-010570-ytv7dwr0	184	20	patients	patient	NNS
cord-010570-ytv7dwr0	184	21	[	[	-LRB-
cord-010570-ytv7dwr0	184	22	123	123	CD
cord-010570-ytv7dwr0	184	23	]	]	-RRB-
cord-010570-ytv7dwr0	184	24	and	and	CC
cord-010570-ytv7dwr0	184	25	most	most	JJS
cord-010570-ytv7dwr0	184	26	patients	patient	NNS
cord-010570-ytv7dwr0	184	27	develop	develop	VBP
cord-010570-ytv7dwr0	184	28	antibody	antibody	NN
cord-010570-ytv7dwr0	184	29	responses	response	NNS
cord-010570-ytv7dwr0	184	30	to	to	IN
cord-010570-ytv7dwr0	184	31	the	the	DT
cord-010570-ytv7dwr0	184	32	murine	murine	JJ
cord-010570-ytv7dwr0	184	33	mAbs	mabs	NN
cord-010570-ytv7dwr0	184	34	that	that	WDT
cord-010570-ytv7dwr0	184	35	may	may	MD
cord-010570-ytv7dwr0	184	36	interfere	interfere	VB
cord-010570-ytv7dwr0	184	37	with	with	IN
cord-010570-ytv7dwr0	184	38	their	-PRON-	PRP$
cord-010570-ytv7dwr0	184	39	therapeutic	therapeutic	JJ
cord-010570-ytv7dwr0	184	40	function	function	NN
cord-010570-ytv7dwr0	184	41	[	[	-LRB-
cord-010570-ytv7dwr0	184	42	43	43	CD
cord-010570-ytv7dwr0	184	43	,	,	,
cord-010570-ytv7dwr0	184	44	124	124	CD
cord-010570-ytv7dwr0	184	45	]	]	-RRB-
cord-010570-ytv7dwr0	184	46	.	.	.
cord-010570-ytv7dwr0	185	1	Experience	experience	NN
cord-010570-ytv7dwr0	185	2	with	with	IN
cord-010570-ytv7dwr0	185	3	human	human	JJ
cord-010570-ytv7dwr0	185	4	-	-	HYPH
cord-010570-ytv7dwr0	185	5	mouse	mouse	NN
cord-010570-ytv7dwr0	185	6	chimeric	chimeric	JJ
cord-010570-ytv7dwr0	185	7	antibodies	antibody	NNS
cord-010570-ytv7dwr0	185	8	and	and	CC
cord-010570-ytv7dwr0	185	9	humanized	humanize	VBN
cord-010570-ytv7dwr0	185	10	mAbs	mAbs	NNP
cord-010570-ytv7dwr0	185	11	is	be	VBZ
cord-010570-ytv7dwr0	185	12	accumulating	accumulate	VBG
cord-010570-ytv7dwr0	185	13	rapidly	rapidly	RB
cord-010570-ytv7dwr0	185	14	as	as	IN
cord-010570-ytv7dwr0	185	15	clinical	clinical	JJ
cord-010570-ytv7dwr0	185	16	trials	trial	NNS
cord-010570-ytv7dwr0	185	17	with	with	IN
cord-010570-ytv7dwr0	185	18	several	several	JJ
cord-010570-ytv7dwr0	185	19	compounds	compound	NNS
cord-010570-ytv7dwr0	185	20	progress	progress	VBP
cord-010570-ytv7dwr0	185	21	.	.	.
cord-010570-ytv7dwr0	186	1	A	a	DT
cord-010570-ytv7dwr0	186	2	chimeric	chimeric	JJ
cord-010570-ytv7dwr0	186	3	anti	anti	JJ
cord-010570-ytv7dwr0	186	4	-	-	JJ
cord-010570-ytv7dwr0	186	5	CD4	cd4	JJ
cord-010570-ytv7dwr0	186	6	mAb	mAb	NNS
cord-010570-ytv7dwr0	186	7	for	for	IN
cord-010570-ytv7dwr0	186	8	the	the	DT
cord-010570-ytv7dwr0	186	9	treatment	treatment	NN
cord-010570-ytv7dwr0	186	10	of	of	IN
cord-010570-ytv7dwr0	186	11	rheumatoid	rheumatoid	NN
cord-010570-ytv7dwr0	186	12	arthritis	arthritis	NN
cord-010570-ytv7dwr0	186	13	has	have	VBZ
cord-010570-ytv7dwr0	186	14	been	be	VBN
cord-010570-ytv7dwr0	186	15	well	well	RB
cord-010570-ytv7dwr0	186	16	tolerated	tolerate	VBN
cord-010570-ytv7dwr0	186	17	[	[	-LRB-
cord-010570-ytv7dwr0	186	18	125	125	CD
cord-010570-ytv7dwr0	186	19	]	]	-RRB-
cord-010570-ytv7dwr0	186	20	,	,	,
cord-010570-ytv7dwr0	186	21	but	but	CC
cord-010570-ytv7dwr0	186	22	approximately	approximately	RB
cord-010570-ytv7dwr0	186	23	half	half	PDT
cord-010570-ytv7dwr0	186	24	the	the	DT
cord-010570-ytv7dwr0	186	25	patients	patient	NNS
cord-010570-ytv7dwr0	186	26	had	have	VBD
cord-010570-ytv7dwr0	186	27	infusion	infusion	NN
cord-010570-ytv7dwr0	186	28	-	-	HYPH
cord-010570-ytv7dwr0	186	29	related	relate	VBN
cord-010570-ytv7dwr0	186	30	side	side	NN
cord-010570-ytv7dwr0	186	31	effects	effect	NNS
cord-010570-ytv7dwr0	186	32	(	(	-LRB-
cord-010570-ytv7dwr0	186	33	headaches	headache	NNS
cord-010570-ytv7dwr0	186	34	,	,	,
cord-010570-ytv7dwr0	186	35	nausea	nausea	NN
cord-010570-ytv7dwr0	186	36	,	,	,
cord-010570-ytv7dwr0	186	37	fever	fever	NN
cord-010570-ytv7dwr0	186	38	,	,	,
cord-010570-ytv7dwr0	186	39	and	and	CC
cord-010570-ytv7dwr0	186	40	chills	chill	NNS
cord-010570-ytv7dwr0	186	41	)	)	-RRB-
cord-010570-ytv7dwr0	186	42	,	,	,
cord-010570-ytv7dwr0	186	43	which	which	WDT
cord-010570-ytv7dwr0	186	44	were	be	VBD
cord-010570-ytv7dwr0	186	45	diminished	diminish	VBN
cord-010570-ytv7dwr0	186	46	by	by	IN
cord-010570-ytv7dwr0	186	47	slowing	slow	VBG
cord-010570-ytv7dwr0	186	48	the	the	DT
cord-010570-ytv7dwr0	186	49	infusion	infusion	NN
cord-010570-ytv7dwr0	186	50	rate	rate	NN
cord-010570-ytv7dwr0	186	51	[	[	-LRB-
cord-010570-ytv7dwr0	186	52	125	125	CD
cord-010570-ytv7dwr0	186	53	]	]	-RRB-
cord-010570-ytv7dwr0	186	54	.	.	.
cord-010570-ytv7dwr0	187	1	Mouse	mouse	NN
cord-010570-ytv7dwr0	187	2	-	-	HYPH
cord-010570-ytv7dwr0	187	3	human	human	JJ
cord-010570-ytv7dwr0	187	4	chimeric	chimeric	JJ
cord-010570-ytv7dwr0	187	5	and	and	CC
cord-010570-ytv7dwr0	187	6	humanized	humanized	JJ
cord-010570-ytv7dwr0	187	7	mAbs	mAbs	NNP
cord-010570-ytv7dwr0	187	8	are	be	VBP
cord-010570-ytv7dwr0	187	9	less	less	RBR
cord-010570-ytv7dwr0	187	10	immunogenic	immunogenic	JJ
cord-010570-ytv7dwr0	187	11	than	than	IN
cord-010570-ytv7dwr0	187	12	their	-PRON-	PRP$
cord-010570-ytv7dwr0	187	13	murine	murine	JJ
cord-010570-ytv7dwr0	187	14	precursors	precursor	NNS
cord-010570-ytv7dwr0	187	15	[	[	-LRB-
cord-010570-ytv7dwr0	187	16	98	98	CD
cord-010570-ytv7dwr0	187	17	,	,	,
cord-010570-ytv7dwr0	187	18	126	126	CD
cord-010570-ytv7dwr0	187	19	]	]	-RRB-
cord-010570-ytv7dwr0	187	20	,	,	,
cord-010570-ytv7dwr0	187	21	but	but	CC
cord-010570-ytv7dwr0	187	22	antiidiotypic	antiidiotypic	JJ
cord-010570-ytv7dwr0	187	23	responses	response	NNS
cord-010570-ytv7dwr0	187	24	occur	occur	VBP
cord-010570-ytv7dwr0	187	25	after	after	IN
cord-010570-ytv7dwr0	187	26	repeated	repeat	VBN
cord-010570-ytv7dwr0	187	27	treatments	treatment	NNS
cord-010570-ytv7dwr0	187	28	[	[	-LRB-
cord-010570-ytv7dwr0	187	29	127	127	CD
cord-010570-ytv7dwr0	187	30	]	]	-RRB-
cord-010570-ytv7dwr0	187	31	.	.	.
cord-010570-ytv7dwr0	188	1	Overall	overall	RB
cord-010570-ytv7dwr0	188	2	,	,	,
cord-010570-ytv7dwr0	188	3	the	the	DT
cord-010570-ytv7dwr0	188	4	experience	experience	NN
cord-010570-ytv7dwr0	188	5	with	with	IN
cord-010570-ytv7dwr0	188	6	chimeric	chimeric	JJ
cord-010570-ytv7dwr0	188	7	and	and	CC
cord-010570-ytv7dwr0	188	8	humanized	humanized	JJ
cord-010570-ytv7dwr0	188	9	mAbs	mAbs	NNP
cord-010570-ytv7dwr0	188	10	suggests	suggest	VBZ
cord-010570-ytv7dwr0	188	11	that	that	IN
cord-010570-ytv7dwr0	188	12	they	-PRON-	PRP
cord-010570-ytv7dwr0	188	13	are	be	VBP
cord-010570-ytv7dwr0	188	14	relatively	relatively	RB
cord-010570-ytv7dwr0	188	15	safe	safe	JJ
cord-010570-ytv7dwr0	188	16	compounds	compound	NNS
cord-010570-ytv7dwr0	188	17	[	[	-LRB-
cord-010570-ytv7dwr0	188	18	98	98	CD
cord-010570-ytv7dwr0	188	19	,	,	,
cord-010570-ytv7dwr0	188	20	[	[	-LRB-
cord-010570-ytv7dwr0	188	21	125	125	CD
cord-010570-ytv7dwr0	188	22	]	]	-RRB-
cord-010570-ytv7dwr0	188	23	[	[	-LRB-
cord-010570-ytv7dwr0	188	24	126	126	CD
cord-010570-ytv7dwr0	188	25	]	]	-RRB-
cord-010570-ytv7dwr0	188	26	[	[	-LRB-
cord-010570-ytv7dwr0	188	27	127	127	CD
cord-010570-ytv7dwr0	188	28	]	]	-RRB-
cord-010570-ytv7dwr0	188	29	[	[	-LRB-
cord-010570-ytv7dwr0	188	30	128	128	CD
cord-010570-ytv7dwr0	188	31	]	]	-RRB-
cord-010570-ytv7dwr0	188	32	.	.	.
cord-010570-ytv7dwr0	189	1	Antigenic	antigenic	JJ
cord-010570-ytv7dwr0	189	2	variation	variation	NN
cord-010570-ytv7dwr0	189	3	and	and	CC
cord-010570-ytv7dwr0	189	4	antibody	antibody	NN
cord-010570-ytv7dwr0	189	5	resistance	resistance	NN
cord-010570-ytv7dwr0	189	6	.	.	.
cord-010570-ytv7dwr0	190	1	The	the	DT
cord-010570-ytv7dwr0	190	2	efficacy	efficacy	NN
cord-010570-ytv7dwr0	190	3	of	of	IN
cord-010570-ytv7dwr0	190	4	antibody	antibody	NN
cord-010570-ytv7dwr0	190	5	-	-	HYPH
cord-010570-ytv7dwr0	190	6	based	base	VBN
cord-010570-ytv7dwr0	190	7	therapies	therapy	NNS
cord-010570-ytv7dwr0	190	8	may	may	MD
cord-010570-ytv7dwr0	190	9	be	be	VB
cord-010570-ytv7dwr0	190	10	diminished	diminish	VBN
cord-010570-ytv7dwr0	190	11	by	by	IN
cord-010570-ytv7dwr0	190	12	antigenic	antigenic	JJ
cord-010570-ytv7dwr0	190	13	changes	change	NNS
cord-010570-ytv7dwr0	190	14	in	in	IN
cord-010570-ytv7dwr0	190	15	the	the	DT
cord-010570-ytv7dwr0	190	16	pathogen	pathogen	NN
cord-010570-ytv7dwr0	190	17	.	.	.
cord-010570-ytv7dwr0	191	1	This	this	DT
cord-010570-ytv7dwr0	191	2	could	could	MD
cord-010570-ytv7dwr0	191	3	be	be	VB
cord-010570-ytv7dwr0	191	4	minimized	minimize	VBN
cord-010570-ytv7dwr0	191	5	by	by	IN
cord-010570-ytv7dwr0	191	6	antigenic	antigenic	JJ
cord-010570-ytv7dwr0	191	7	surveillance	surveillance	NN
cord-010570-ytv7dwr0	191	8	systems	system	NNS
cord-010570-ytv7dwr0	191	9	,	,	,
cord-010570-ytv7dwr0	191	10	as	as	IN
cord-010570-ytv7dwr0	191	11	is	be	VBZ
cord-010570-ytv7dwr0	191	12	presently	presently	RB
cord-010570-ytv7dwr0	191	13	done	do	VBN
cord-010570-ytv7dwr0	191	14	for	for	IN
cord-010570-ytv7dwr0	191	15	influenza	influenza	NN
cord-010570-ytv7dwr0	191	16	virus	virus	NN
cord-010570-ytv7dwr0	191	17	.	.	.
cord-010570-ytv7dwr0	192	1	Antibody	antibody	NN
cord-010570-ytv7dwr0	192	2	-	-	HYPH
cord-010570-ytv7dwr0	192	3	resistant	resistant	JJ
cord-010570-ytv7dwr0	192	4	mutants	mutant	NNS
cord-010570-ytv7dwr0	192	5	can	can	MD
cord-010570-ytv7dwr0	192	6	be	be	VB
cord-010570-ytv7dwr0	192	7	generated	generate	VBN
cord-010570-ytv7dwr0	192	8	in	in	IN
cord-010570-ytv7dwr0	192	9	the	the	DT
cord-010570-ytv7dwr0	192	10	laboratory	laboratory	NN
cord-010570-ytv7dwr0	192	11	[	[	-LRB-
cord-010570-ytv7dwr0	192	12	129	129	CD
cord-010570-ytv7dwr0	192	13	]	]	-RRB-
cord-010570-ytv7dwr0	192	14	,	,	,
cord-010570-ytv7dwr0	192	15	and	and	CC
cord-010570-ytv7dwr0	192	16	it	-PRON-	PRP
cord-010570-ytv7dwr0	192	17	is	be	VBZ
cord-010570-ytv7dwr0	192	18	likely	likely	JJ
cord-010570-ytv7dwr0	192	19	that	that	IN
cord-010570-ytv7dwr0	192	20	the	the	DT
cord-010570-ytv7dwr0	192	21	same	same	JJ
cord-010570-ytv7dwr0	192	22	can	can	MD
cord-010570-ytv7dwr0	192	23	occur	occur	VB
cord-010570-ytv7dwr0	192	24	in	in	IN
cord-010570-ytv7dwr0	192	25	patients	patient	NNS
cord-010570-ytv7dwr0	192	26	.	.	.
cord-010570-ytv7dwr0	193	1	Mechanisms	mechanism	NNS
cord-010570-ytv7dwr0	193	2	of	of	IN
cord-010570-ytv7dwr0	193	3	antibody	antibody	NN
cord-010570-ytv7dwr0	193	4	resistance	resistance	NN
cord-010570-ytv7dwr0	193	5	include	include	VBP
cord-010570-ytv7dwr0	193	6	mutations	mutation	NNS
cord-010570-ytv7dwr0	193	7	that	that	WDT
cord-010570-ytv7dwr0	193	8	change	change	VBP
cord-010570-ytv7dwr0	193	9	the	the	DT
cord-010570-ytv7dwr0	193	10	antigenic	antigenic	JJ
cord-010570-ytv7dwr0	193	11	site	site	NN
cord-010570-ytv7dwr0	193	12	and	and	CC
cord-010570-ytv7dwr0	193	13	protease	protease	NN
cord-010570-ytv7dwr0	193	14	production	production	NN
cord-010570-ytv7dwr0	193	15	.	.	.
cord-010570-ytv7dwr0	194	1	Antibody	antibody	NN
cord-010570-ytv7dwr0	194	2	use	use	NN
cord-010570-ytv7dwr0	194	3	may	may	MD
cord-010570-ytv7dwr0	194	4	select	select	VB
cord-010570-ytv7dwr0	194	5	for	for	IN
cord-010570-ytv7dwr0	194	6	antigenically	antigenically	RB
cord-010570-ytv7dwr0	194	7	distinct	distinct	JJ
cord-010570-ytv7dwr0	194	8	variants	variant	NNS
cord-010570-ytv7dwr0	194	9	.	.	.
cord-010570-ytv7dwr0	195	1	Evidence	evidence	NN
cord-010570-ytv7dwr0	195	2	for	for	IN
cord-010570-ytv7dwr0	195	3	the	the	DT
cord-010570-ytv7dwr0	195	4	horizontal	horizontal	JJ
cord-010570-ytv7dwr0	195	5	transfer	transfer	NN
cord-010570-ytv7dwr0	195	6	of	of	IN
cord-010570-ytv7dwr0	195	7	IgA	IgA	NNP
cord-010570-ytv7dwr0	195	8	protease	protease	NN
cord-010570-ytv7dwr0	195	9	genes	gene	NNS
cord-010570-ytv7dwr0	195	10	exists	exist	VBZ
cord-010570-ytv7dwr0	195	11	in	in	IN
cord-010570-ytv7dwr0	195	12	Neisseria	Neisseria	NNP
cord-010570-ytv7dwr0	195	13	gonorrhoeae	gonorrhoeae	NNP
cord-010570-ytv7dwr0	195	14	and	and	CC
cord-010570-ytv7dwr0	195	15	it	-PRON-	PRP
cord-010570-ytv7dwr0	195	16	is	be	VBZ
cord-010570-ytv7dwr0	195	17	conceivable	conceivable	JJ
cord-010570-ytv7dwr0	195	18	that	that	IN
cord-010570-ytv7dwr0	195	19	widespread	widespread	JJ
cord-010570-ytv7dwr0	195	20	antibody	antibody	NN
cord-010570-ytv7dwr0	195	21	use	use	NN
cord-010570-ytv7dwr0	195	22	would	would	MD
cord-010570-ytv7dwr0	195	23	result	result	VB
cord-010570-ytv7dwr0	195	24	in	in	IN
cord-010570-ytv7dwr0	195	25	selection	selection	NN
cord-010570-ytv7dwr0	195	26	of	of	IN
cord-010570-ytv7dwr0	195	27	protease	protease	NN
cord-010570-ytv7dwr0	195	28	-	-	HYPH
cord-010570-ytv7dwr0	195	29	producing	produce	VBG
cord-010570-ytv7dwr0	195	30	strains	strain	NNS
cord-010570-ytv7dwr0	195	31	for	for	IN
cord-010570-ytv7dwr0	195	32	many	many	JJ
cord-010570-ytv7dwr0	195	33	pathogens	pathogen	NNS
cord-010570-ytv7dwr0	195	34	[	[	-LRB-
cord-010570-ytv7dwr0	195	35	130	130	CD
cord-010570-ytv7dwr0	195	36	]	]	-RRB-
cord-010570-ytv7dwr0	195	37	.	.	.
cord-010570-ytv7dwr0	196	1	Thus	thus	RB
cord-010570-ytv7dwr0	196	2	,	,	,
cord-010570-ytv7dwr0	196	3	large	large	JJ
cord-010570-ytv7dwr0	196	4	-	-	HYPH
cord-010570-ytv7dwr0	196	5	scale	scale	NN
cord-010570-ytv7dwr0	196	6	use	use	NN
cord-010570-ytv7dwr0	196	7	of	of	IN
cord-010570-ytv7dwr0	196	8	antibody	antibody	NN
cord-010570-ytv7dwr0	196	9	-	-	HYPH
cord-010570-ytv7dwr0	196	10	based	base	VBN
cord-010570-ytv7dwr0	196	11	therapies	therapy	NNS
cord-010570-ytv7dwr0	196	12	may	may	MD
cord-010570-ytv7dwr0	196	13	result	result	VB
cord-010570-ytv7dwr0	196	14	in	in	IN
cord-010570-ytv7dwr0	196	15	rapid	rapid	JJ
cord-010570-ytv7dwr0	196	16	emergence	emergence	NN
cord-010570-ytv7dwr0	196	17	of	of	IN
cord-010570-ytv7dwr0	196	18	antibody	antibody	NN
cord-010570-ytv7dwr0	196	19	resistance	resistance	NN
cord-010570-ytv7dwr0	196	20	in	in	IN
cord-010570-ytv7dwr0	196	21	a	a	DT
cord-010570-ytv7dwr0	196	22	manner	manner	NN
cord-010570-ytv7dwr0	196	23	analogous	analogous	JJ
cord-010570-ytv7dwr0	196	24	to	to	IN
cord-010570-ytv7dwr0	196	25	that	that	DT
cord-010570-ytv7dwr0	196	26	of	of	IN
cord-010570-ytv7dwr0	196	27	antibiotic	antibiotic	JJ
cord-010570-ytv7dwr0	196	28	resistance	resistance	NN
cord-010570-ytv7dwr0	196	29	.	.	.
cord-010570-ytv7dwr0	197	1	However	however	RB
cord-010570-ytv7dwr0	197	2	,	,	,
cord-010570-ytv7dwr0	197	3	one	one	CD
cord-010570-ytv7dwr0	197	4	advantage	advantage	NN
cord-010570-ytv7dwr0	197	5	of	of	IN
cord-010570-ytv7dwr0	197	6	antibody	antibody	NN
cord-010570-ytv7dwr0	197	7	-	-	HYPH
cord-010570-ytv7dwr0	197	8	based	base	VBN
cord-010570-ytv7dwr0	197	9	therapies	therapy	NNS
cord-010570-ytv7dwr0	197	10	is	be	VBZ
cord-010570-ytv7dwr0	197	11	the	the	DT
cord-010570-ytv7dwr0	197	12	versatility	versatility	NN
cord-010570-ytv7dwr0	197	13	of	of	IN
cord-010570-ytv7dwr0	197	14	antibody	antibody	NN
cord-010570-ytv7dwr0	197	15	compounds	compound	NNS
cord-010570-ytv7dwr0	197	16	.	.	.
cord-010570-ytv7dwr0	198	1	For	for	IN
cord-010570-ytv7dwr0	198	2	example	example	NN
cord-010570-ytv7dwr0	198	3	,	,	,
cord-010570-ytv7dwr0	198	4	emergence	emergence	NN
cord-010570-ytv7dwr0	198	5	of	of	IN
cord-010570-ytv7dwr0	198	6	an	an	DT
cord-010570-ytv7dwr0	198	7	antibodyresistant	antibodyresistant	NN
cord-010570-ytv7dwr0	198	8	strain	strain	NN
cord-010570-ytv7dwr0	198	9	could	could	MD
cord-010570-ytv7dwr0	198	10	be	be	VB
cord-010570-ytv7dwr0	198	11	countered	counter	VBN
cord-010570-ytv7dwr0	198	12	by	by	IN
cord-010570-ytv7dwr0	198	13	a	a	DT
cord-010570-ytv7dwr0	198	14	new	new	JJ
cord-010570-ytv7dwr0	198	15	antibody	antibody	NN
cord-010570-ytv7dwr0	198	16	directed	direct	VBN
cord-010570-ytv7dwr0	198	17	toward	toward	IN
cord-010570-ytv7dwr0	198	18	the	the	DT
cord-010570-ytv7dwr0	198	19	mutated	mutated	JJ
cord-010570-ytv7dwr0	198	20	epitope	epitope	NN
cord-010570-ytv7dwr0	198	21	or	or	CC
cord-010570-ytv7dwr0	198	22	another	another	DT
cord-010570-ytv7dwr0	198	23	antigenic	antigenic	JJ
cord-010570-ytv7dwr0	198	24	target	target	NN
cord-010570-ytv7dwr0	198	25	.	.	.
cord-010570-ytv7dwr0	199	1	Emergence	emergence	NN
cord-010570-ytv7dwr0	199	2	of	of	IN
cord-010570-ytv7dwr0	199	3	protease	protease	NN
cord-010570-ytv7dwr0	199	4	-	-	HYPH
cord-010570-ytv7dwr0	199	5	producing	produce	VBG
cord-010570-ytv7dwr0	199	6	strains	strain	NNS
cord-010570-ytv7dwr0	199	7	could	could	MD
cord-010570-ytv7dwr0	199	8	be	be	VB
cord-010570-ytv7dwr0	199	9	countered	counter	VBN
cord-010570-ytv7dwr0	199	10	by	by	IN
cord-010570-ytv7dwr0	199	11	designing	design	VBG
cord-010570-ytv7dwr0	199	12	antibodies	antibody	NNS
cord-010570-ytv7dwr0	199	13	without	without	IN
cord-010570-ytv7dwr0	199	14	protease	protease	NN
cord-010570-ytv7dwr0	199	15	cleavage	cleavage	NN
cord-010570-ytv7dwr0	199	16	sites	site	NNS
cord-010570-ytv7dwr0	199	17	(	(	-LRB-
cord-010570-ytv7dwr0	199	18	although	although	IN
cord-010570-ytv7dwr0	199	19	these	these	DT
cord-010570-ytv7dwr0	199	20	may	may	MD
cord-010570-ytv7dwr0	199	21	then	then	RB
cord-010570-ytv7dwr0	199	22	be	be	VB
cord-010570-ytv7dwr0	199	23	recognized	recognize	VBN
cord-010570-ytv7dwr0	199	24	as	as	IN
cord-010570-ytv7dwr0	199	25	foreign	foreign	JJ
cord-010570-ytv7dwr0	199	26	and	and	CC
cord-010570-ytv7dwr0	199	27	be	be	VB
cord-010570-ytv7dwr0	199	28	immunogenic	immunogenic	JJ
cord-010570-ytv7dwr0	199	29	)	)	-RRB-
cord-010570-ytv7dwr0	199	30	or	or	CC
cord-010570-ytv7dwr0	199	31	by	by	IN
cord-010570-ytv7dwr0	199	32	addition	addition	NN
cord-010570-ytv7dwr0	199	33	of	of	IN
cord-010570-ytv7dwr0	199	34	antiprotease	antiprotease	NNP
cord-010570-ytv7dwr0	199	35	mAbs	mAbs	NNP
cord-010570-ytv7dwr0	199	36	.	.	.
cord-010570-ytv7dwr0	200	1	Selection	selection	NN
cord-010570-ytv7dwr0	200	2	of	of	IN
cord-010570-ytv7dwr0	200	3	antibodyresistant	antibodyresistant	NN
cord-010570-ytv7dwr0	200	4	organisms	organism	NNS
cord-010570-ytv7dwr0	200	5	could	could	MD
cord-010570-ytv7dwr0	200	6	be	be	VB
cord-010570-ytv7dwr0	200	7	minimized	minimize	VBN
cord-010570-ytv7dwr0	200	8	by	by	IN
cord-010570-ytv7dwr0	200	9	using	use	VBG
cord-010570-ytv7dwr0	200	10	cocktails	cocktail	NNS
cord-010570-ytv7dwr0	200	11	of	of	IN
cord-010570-ytv7dwr0	200	12	mAbs	mabs	NN
cord-010570-ytv7dwr0	200	13	directed	direct	VBN
cord-010570-ytv7dwr0	200	14	at	at	IN
cord-010570-ytv7dwr0	200	15	multiple	multiple	JJ
cord-010570-ytv7dwr0	200	16	antigenic	antigenic	JJ
cord-010570-ytv7dwr0	200	17	targets	target	NNS
cord-010570-ytv7dwr0	200	18	or	or	CC
cord-010570-ytv7dwr0	200	19	by	by	IN
cord-010570-ytv7dwr0	200	20	using	use	VBG
cord-010570-ytv7dwr0	200	21	a	a	DT
cord-010570-ytv7dwr0	200	22	combination	combination	NN
cord-010570-ytv7dwr0	200	23	of	of	IN
cord-010570-ytv7dwr0	200	24	antibodies	antibody	NNS
cord-010570-ytv7dwr0	200	25	and	and	CC
cord-010570-ytv7dwr0	200	26	antimicrobials	antimicrobial	NNS
cord-010570-ytv7dwr0	200	27	.	.	.
cord-010570-ytv7dwr0	201	1	Cost	cost	NN
cord-010570-ytv7dwr0	201	2	.	.	.
cord-010570-ytv7dwr0	202	1	Cost	cost	NN
cord-010570-ytv7dwr0	202	2	effectiveness	effectiveness	NN
cord-010570-ytv7dwr0	202	3	is	be	VBZ
cord-010570-ytv7dwr0	202	4	a	a	DT
cord-010570-ytv7dwr0	202	5	significant	significant	JJ
cord-010570-ytv7dwr0	202	6	concern	concern	NN
cord-010570-ytv7dwr0	202	7	that	that	WDT
cord-010570-ytv7dwr0	202	8	is	be	VBZ
cord-010570-ytv7dwr0	202	9	likely	likely	JJ
cord-010570-ytv7dwr0	202	10	to	to	TO
cord-010570-ytv7dwr0	202	11	be	be	VB
cord-010570-ytv7dwr0	202	12	a	a	DT
cord-010570-ytv7dwr0	202	13	major	major	JJ
cord-010570-ytv7dwr0	202	14	obstacle	obstacle	NN
cord-010570-ytv7dwr0	202	15	for	for	IN
cord-010570-ytv7dwr0	202	16	the	the	DT
cord-010570-ytv7dwr0	202	17	development	development	NN
cord-010570-ytv7dwr0	202	18	of	of	IN
cord-010570-ytv7dwr0	202	19	passive	passive	JJ
cord-010570-ytv7dwr0	202	20	antibody	antibody	NN
cord-010570-ytv7dwr0	202	21	therapies	therapy	NNS
cord-010570-ytv7dwr0	202	22	.	.	.
cord-010570-ytv7dwr0	203	1	Antibody	antibody	NN
cord-010570-ytv7dwr0	203	2	prophylaxis	prophylaxis	NN
cord-010570-ytv7dwr0	203	3	for	for	IN
cord-010570-ytv7dwr0	203	4	CMV	CMV	NNP
cord-010570-ytv7dwr0	203	5	infections	infection	NNS
cord-010570-ytv7dwr0	203	6	can	can	MD
cord-010570-ytv7dwr0	203	7	cost	cost	VB
cord-010570-ytv7dwr0	203	8	$	$	$
cord-010570-ytv7dwr0	203	9	4,000	4,000	CD
cord-010570-ytv7dwr0	203	10	to	to	TO
cord-010570-ytv7dwr0	203	11	$	$	$
cord-010570-ytv7dwr0	203	12	9,000	9,000	CD
cord-010570-ytv7dwr0	203	13	per	per	IN
cord-010570-ytv7dwr0	203	14	patient	patient	NN
cord-010570-ytv7dwr0	203	15	[	[	-LRB-
cord-010570-ytv7dwr0	203	16	71	71	CD
cord-010570-ytv7dwr0	203	17	]	]	-RRB-
cord-010570-ytv7dwr0	203	18	.	.	.
cord-010570-ytv7dwr0	204	1	The	the	DT
cord-010570-ytv7dwr0	204	2	cost	cost	NN
cord-010570-ytv7dwr0	204	3	effectiveness	effectiveness	NN
cord-010570-ytv7dwr0	204	4	of	of	IN
cord-010570-ytv7dwr0	204	5	antibody	antibody	NN
cord-010570-ytv7dwr0	204	6	therapy	therapy	NN
cord-010570-ytv7dwr0	204	7	for	for	IN
cord-010570-ytv7dwr0	204	8	prevention	prevention	NN
cord-010570-ytv7dwr0	204	9	of	of	IN
cord-010570-ytv7dwr0	204	10	infection	infection	NN
cord-010570-ytv7dwr0	204	11	in	in	IN
cord-010570-ytv7dwr0	204	12	leukemic	leukemic	JJ
cord-010570-ytv7dwr0	204	13	patients	patient	NNS
cord-010570-ytv7dwr0	204	14	has	have	VBZ
cord-010570-ytv7dwr0	204	15	been	be	VBN
cord-010570-ytv7dwr0	204	16	questioned	question	VBN
cord-010570-ytv7dwr0	204	17	[	[	-LRB-
cord-010570-ytv7dwr0	204	18	88	88	CD
cord-010570-ytv7dwr0	204	19	,	,	,
cord-010570-ytv7dwr0	204	20	131	131	CD
cord-010570-ytv7dwr0	204	21	]	]	-RRB-
cord-010570-ytv7dwr0	204	22	.	.	.
cord-010570-ytv7dwr0	205	1	However	however	RB
cord-010570-ytv7dwr0	205	2	,	,	,
cord-010570-ytv7dwr0	205	3	in	in	IN
cord-010570-ytv7dwr0	205	4	selected	select	VBN
cord-010570-ytv7dwr0	205	5	populations	population	NNS
cord-010570-ytv7dwr0	205	6	such	such	JJ
cord-010570-ytv7dwr0	205	7	as	as	IN
cord-010570-ytv7dwr0	205	8	premature	premature	JJ
cord-010570-ytv7dwr0	205	9	infants	infant	NNS
cord-010570-ytv7dwr0	205	10	,	,	,
cord-010570-ytv7dwr0	205	11	antibody	antibody	NN
cord-010570-ytv7dwr0	205	12	therapy	therapy	NN
cord-010570-ytv7dwr0	205	13	may	may	MD
cord-010570-ytv7dwr0	205	14	be	be	VB
cord-010570-ytv7dwr0	205	15	cost	cost	VBN
cord-010570-ytv7dwr0	205	16	effective	effective	JJ
cord-010570-ytv7dwr0	205	17	[	[	-LRB-
cord-010570-ytv7dwr0	205	18	85	85	CD
cord-010570-ytv7dwr0	205	19	]	]	-RRB-
cord-010570-ytv7dwr0	205	20	.	.	.
cord-010570-ytv7dwr0	206	1	Furthermore	furthermore	RB
cord-010570-ytv7dwr0	206	2	,	,	,
cord-010570-ytv7dwr0	206	3	the	the	DT
cord-010570-ytv7dwr0	206	4	cost	cost	NN
cord-010570-ytv7dwr0	206	5	of	of	IN
cord-010570-ytv7dwr0	206	6	a	a	DT
cord-010570-ytv7dwr0	206	7	drug	drug	NN
cord-010570-ytv7dwr0	206	8	when	when	WRB
cord-010570-ytv7dwr0	206	9	first	first	RB
cord-010570-ytv7dwr0	206	10	introduced	introduce	VBN
cord-010570-ytv7dwr0	206	11	may	may	MD
cord-010570-ytv7dwr0	206	12	not	not	RB
cord-010570-ytv7dwr0	206	13	reflect	reflect	VB
cord-010570-ytv7dwr0	206	14	its	-PRON-	PRP$
cord-010570-ytv7dwr0	206	15	long	long	JJ
cord-010570-ytv7dwr0	206	16	-	-	HYPH
cord-010570-ytv7dwr0	206	17	term	term	NN
cord-010570-ytv7dwr0	206	18	costs	cost	NNS
cord-010570-ytv7dwr0	206	19	given	give	VBN
cord-010570-ytv7dwr0	206	20	the	the	DT
cord-010570-ytv7dwr0	206	21	potential	potential	NN
cord-010570-ytv7dwr0	206	22	for	for	IN
cord-010570-ytv7dwr0	206	23	improvements	improvement	NNS
cord-010570-ytv7dwr0	206	24	in	in	IN
cord-010570-ytv7dwr0	206	25	technology	technology	NN
cord-010570-ytv7dwr0	206	26	and	and	CC
cord-010570-ytv7dwr0	206	27	production	production	NN
cord-010570-ytv7dwr0	206	28	.	.	.
cord-010570-ytv7dwr0	207	1	mAbs	mAbs	NNP
cord-010570-ytv7dwr0	207	2	are	be	VBP
cord-010570-ytv7dwr0	207	3	presently	presently	RB
cord-010570-ytv7dwr0	207	4	made	make	VBN
cord-010570-ytv7dwr0	207	5	in	in	IN
cord-010570-ytv7dwr0	207	6	tissue	tissue	NN
cord-010570-ytv7dwr0	207	7	culture	culture	NN
cord-010570-ytv7dwr0	207	8	,	,	,
cord-010570-ytv7dwr0	207	9	so	so	CC
cord-010570-ytv7dwr0	207	10	the	the	DT
cord-010570-ytv7dwr0	207	11	cost	cost	NN
cord-010570-ytv7dwr0	207	12	of	of	IN
cord-010570-ytv7dwr0	207	13	production	production	NN
cord-010570-ytv7dwr0	207	14	is	be	VBZ
cord-010570-ytv7dwr0	207	15	high	high	JJ
cord-010570-ytv7dwr0	207	16	.	.	.
cord-010570-ytv7dwr0	208	1	mAbs	mabs	NN
cord-010570-ytv7dwr0	208	2	can	can	MD
cord-010570-ytv7dwr0	208	3	be	be	VB
cord-010570-ytv7dwr0	208	4	made	make	VBN
cord-010570-ytv7dwr0	208	5	in	in	IN
cord-010570-ytv7dwr0	208	6	bacteria	bacteria	NNS
cord-010570-ytv7dwr0	208	7	or	or	CC
cord-010570-ytv7dwr0	208	8	yeast	yeast	NN
cord-010570-ytv7dwr0	208	9	,	,	,
cord-010570-ytv7dwr0	208	10	and	and	CC
cord-010570-ytv7dwr0	208	11	less	less	RBR
cord-010570-ytv7dwr0	208	12	costly	costly	JJ
cord-010570-ytv7dwr0	208	13	means	mean	NNS
cord-010570-ytv7dwr0	208	14	of	of	IN
cord-010570-ytv7dwr0	208	15	production	production	NN
cord-010570-ytv7dwr0	208	16	might	may	MD
cord-010570-ytv7dwr0	208	17	be	be	VB
cord-010570-ytv7dwr0	208	18	developed	develop	VBN
cord-010570-ytv7dwr0	208	19	[	[	-LRB-
cord-010570-ytv7dwr0	208	20	97	97	CD
cord-010570-ytv7dwr0	208	21	]	]	-RRB-
cord-010570-ytv7dwr0	208	22	.	.	.
cord-010570-ytv7dwr0	209	1	In	in	IN
cord-010570-ytv7dwr0	209	2	the	the	DT
cord-010570-ytv7dwr0	209	3	past	past	NN
cord-010570-ytv7dwr0	209	4	,	,	,
cord-010570-ytv7dwr0	209	5	serum	serum	NN
cord-010570-ytv7dwr0	209	6	therapy	therapy	NN
cord-010570-ytv7dwr0	209	7	was	be	VBD
cord-010570-ytv7dwr0	209	8	used	use	VBN
cord-010570-ytv7dwr0	209	9	despite	despite	IN
cord-010570-ytv7dwr0	209	10	its	-PRON-	PRP$
cord-010570-ytv7dwr0	209	11	high	high	JJ
cord-010570-ytv7dwr0	209	12	cost	cost	NN
cord-010570-ytv7dwr0	209	13	because	because	IN
cord-010570-ytv7dwr0	209	14	it	-PRON-	PRP
cord-010570-ytv7dwr0	209	15	was	be	VBD
cord-010570-ytv7dwr0	209	16	believed	believe	VBN
cord-010570-ytv7dwr0	209	17	to	to	TO
cord-010570-ytv7dwr0	209	18	be	be	VB
cord-010570-ytv7dwr0	209	19	effective	effective	JJ
cord-010570-ytv7dwr0	209	20	.	.	.
cord-010570-ytv7dwr0	210	1	New	new	JJ
cord-010570-ytv7dwr0	210	2	antibody	antibody	NN
cord-010570-ytv7dwr0	210	3	-	-	HYPH
cord-010570-ytv7dwr0	210	4	based	base	VBN
cord-010570-ytv7dwr0	210	5	therapies	therapy	NNS
cord-010570-ytv7dwr0	210	6	are	be	VBP
cord-010570-ytv7dwr0	210	7	likely	likely	JJ
cord-010570-ytv7dwr0	210	8	to	to	TO
cord-010570-ytv7dwr0	210	9	be	be	VB
cord-010570-ytv7dwr0	210	10	used	use	VBN
cord-010570-ytv7dwr0	210	11	if	if	IN
cord-010570-ytv7dwr0	210	12	they	-PRON-	PRP
cord-010570-ytv7dwr0	210	13	prove	prove	VBP
cord-010570-ytv7dwr0	210	14	to	to	TO
cord-010570-ytv7dwr0	210	15	be	be	VB
cord-010570-ytv7dwr0	210	16	effective	effective	JJ
cord-010570-ytv7dwr0	210	17	.	.	.
cord-010570-ytv7dwr0	211	1	For	for	IN
cord-010570-ytv7dwr0	211	2	pathogens	pathogen	NNS
cord-010570-ytv7dwr0	211	3	such	such	JJ
cord-010570-ytv7dwr0	211	4	as	as	IN
cord-010570-ytv7dwr0	211	5	S.	S.	NNP
cord-010570-ytv7dwr0	211	6	pneumoniae	pneumoniae	NN
cord-010570-ytv7dwr0	211	7	,	,	,
cord-010570-ytv7dwr0	211	8	N.	N.	NNP
cord-010570-ytv7dwr0	211	9	meningitidis	meningitidis	NNP
cord-010570-ytv7dwr0	211	10	,	,	,
cord-010570-ytv7dwr0	211	11	and	and	CC
cord-010570-ytv7dwr0	211	12	H	H	NNP
cord-010570-ytv7dwr0	211	13	infiuenzae	infiuenzae	NN
cord-010570-ytv7dwr0	211	14	,	,	,
cord-010570-ytv7dwr0	211	15	there	there	EX
cord-010570-ytv7dwr0	211	16	is	be	VBZ
cord-010570-ytv7dwr0	211	17	a	a	DT
cord-010570-ytv7dwr0	211	18	large	large	JJ
cord-010570-ytv7dwr0	211	19	body	body	NN
cord-010570-ytv7dwr0	211	20	of	of	IN
cord-010570-ytv7dwr0	211	21	experimental	experimental	JJ
cord-010570-ytv7dwr0	211	22	and	and	CC
cord-010570-ytv7dwr0	211	23	clinical	clinical	JJ
cord-010570-ytv7dwr0	211	24	evidence	evidence	NN
cord-010570-ytv7dwr0	211	25	to	to	TO
cord-010570-ytv7dwr0	211	26	support	support	VB
cord-010570-ytv7dwr0	211	27	the	the	DT
cord-010570-ytv7dwr0	211	28	development	development	NN
cord-010570-ytv7dwr0	211	29	of	of	IN
cord-010570-ytv7dwr0	211	30	passive	passive	JJ
cord-010570-ytv7dwr0	211	31	antibody	antibody	NN
cord-010570-ytv7dwr0	211	32	therapy	therapy	NN
cord-010570-ytv7dwr0	211	33	.	.	.
cord-010570-ytv7dwr0	212	1	However	however	RB
cord-010570-ytv7dwr0	212	2	,	,	,
cord-010570-ytv7dwr0	212	3	for	for	IN
cord-010570-ytv7dwr0	212	4	many	many	JJ
cord-010570-ytv7dwr0	212	5	pathogens	pathogen	NNS
cord-010570-ytv7dwr0	212	6	,	,	,
cord-010570-ytv7dwr0	212	7	antibody	antibody	NN
cord-010570-ytv7dwr0	212	8	immunity	immunity	NN
cord-010570-ytv7dwr0	212	9	has	have	VBZ
cord-010570-ytv7dwr0	212	10	not	not	RB
cord-010570-ytv7dwr0	212	11	been	be	VBN
cord-010570-ytv7dwr0	212	12	proven	prove	VBN
cord-010570-ytv7dwr0	212	13	to	to	TO
cord-010570-ytv7dwr0	212	14	be	be	VB
cord-010570-ytv7dwr0	212	15	important	important	JJ
cord-010570-ytv7dwr0	212	16	.	.	.
cord-010570-ytv7dwr0	213	1	For	for	IN
cord-010570-ytv7dwr0	213	2	example	example	NN
cord-010570-ytv7dwr0	213	3	,	,	,
cord-010570-ytv7dwr0	213	4	Cryptococcus	Cryptococcus	NNP
cord-010570-ytv7dwr0	213	5	neoformans	neoforman	VBZ
cord-010570-ytv7dwr0	213	6	is	be	VBZ
cord-010570-ytv7dwr0	213	7	a	a	DT
cord-010570-ytv7dwr0	213	8	fungus	fungus	NN
cord-010570-ytv7dwr0	213	9	for	for	IN
cord-010570-ytv7dwr0	213	10	which	which	WDT
cord-010570-ytv7dwr0	213	11	the	the	DT
cord-010570-ytv7dwr0	213	12	importance	importance	NN
cord-010570-ytv7dwr0	213	13	of	of	IN
cord-010570-ytv7dwr0	213	14	antibody	antibody	NN
cord-010570-ytv7dwr0	213	15	immunity	immunity	NN
cord-010570-ytv7dwr0	213	16	is	be	VBZ
cord-010570-ytv7dwr0	213	17	uncertain	uncertain	JJ
cord-010570-ytv7dwr0	213	18	.	.	.
cord-010570-ytv7dwr0	214	1	However	however	RB
cord-010570-ytv7dwr0	214	2	,	,	,
cord-010570-ytv7dwr0	214	3	administration	administration	NN
cord-010570-ytv7dwr0	214	4	of	of	IN
cord-010570-ytv7dwr0	214	5	preformed	preformed	JJ
cord-010570-ytv7dwr0	214	6	antibodies	antibody	NNS
cord-010570-ytv7dwr0	214	7	can	can	MD
cord-010570-ytv7dwr0	214	8	modify	modify	VB
cord-010570-ytv7dwr0	214	9	the	the	DT
cord-010570-ytv7dwr0	214	10	course	course	NN
cord-010570-ytv7dwr0	214	11	of	of	IN
cord-010570-ytv7dwr0	214	12	cryptococcal	cryptococcal	JJ
cord-010570-ytv7dwr0	214	13	infection	infection	NN
cord-010570-ytv7dwr0	214	14	in	in	IN
cord-010570-ytv7dwr0	214	15	various	various	JJ
cord-010570-ytv7dwr0	214	16	animal	animal	NN
cord-010570-ytv7dwr0	214	17	models	model	NNS
cord-010570-ytv7dwr0	214	18	[	[	-LRB-
cord-010570-ytv7dwr0	214	19	132	132	CD
cord-010570-ytv7dwr0	214	20	]	]	-RRB-
cord-010570-ytv7dwr0	214	21	[	[	-LRB-
cord-010570-ytv7dwr0	214	22	133	133	CD
cord-010570-ytv7dwr0	214	23	]	]	-RRB-
cord-010570-ytv7dwr0	214	24	[	[	-LRB-
cord-010570-ytv7dwr0	214	25	134	134	CD
cord-010570-ytv7dwr0	214	26	]	]	-RRB-
cord-010570-ytv7dwr0	214	27	[	[	-LRB-
cord-010570-ytv7dwr0	214	28	135	135	CD
cord-010570-ytv7dwr0	214	29	]	]	-RRB-
cord-010570-ytv7dwr0	214	30	[	[	-LRB-
cord-010570-ytv7dwr0	214	31	136	136	CD
cord-010570-ytv7dwr0	214	32	]	]	-RRB-
cord-010570-ytv7dwr0	214	33	,	,	,
cord-010570-ytv7dwr0	214	34	and	and	CC
cord-010570-ytv7dwr0	214	35	the	the	DT
cord-010570-ytv7dwr0	214	36	combination	combination	NN
cord-010570-ytv7dwr0	214	37	of	of	IN
cord-010570-ytv7dwr0	214	38	antibody	antibody	NN
cord-010570-ytv7dwr0	214	39	and	and	CC
cord-010570-ytv7dwr0	214	40	amphotericin	amphotericin	NNS
cord-010570-ytv7dwr0	214	41	B	B	NNP
cord-010570-ytv7dwr0	214	42	is	be	VBZ
cord-010570-ytv7dwr0	214	43	a	a	DT
cord-010570-ytv7dwr0	214	44	more	more	RBR
cord-010570-ytv7dwr0	214	45	effective	effective	JJ
cord-010570-ytv7dwr0	214	46	treatment	treatment	NN
cord-010570-ytv7dwr0	214	47	than	than	IN
cord-010570-ytv7dwr0	214	48	the	the	DT
cord-010570-ytv7dwr0	214	49	use	use	NN
cord-010570-ytv7dwr0	214	50	of	of	IN
cord-010570-ytv7dwr0	214	51	either	either	DT
cord-010570-ytv7dwr0	214	52	agent	agent	NN
cord-010570-ytv7dwr0	214	53	alone	alone	RB
cord-010570-ytv7dwr0	214	54	[	[	-LRB-
cord-010570-ytv7dwr0	214	55	137	137	CD
cord-010570-ytv7dwr0	214	56	]	]	-RRB-
cord-010570-ytv7dwr0	215	1	[	[	-LRB-
cord-010570-ytv7dwr0	215	2	138	138	CD
cord-010570-ytv7dwr0	215	3	]	]	-RRB-
cord-010570-ytv7dwr0	215	4	[	[	-LRB-
cord-010570-ytv7dwr0	215	5	139	139	CD
cord-010570-ytv7dwr0	215	6	]	]	-RRB-
cord-010570-ytv7dwr0	215	7	.	.	.
cord-010570-ytv7dwr0	216	1	Studies	study	NNS
cord-010570-ytv7dwr0	216	2	with	with	IN
cord-010570-ytv7dwr0	216	3	mAbs	mAbs	NNP
cord-010570-ytv7dwr0	216	4	have	have	VBP
cord-010570-ytv7dwr0	216	5	shown	show	VBN
cord-010570-ytv7dwr0	216	6	that	that	IN
cord-010570-ytv7dwr0	216	7	there	there	EX
cord-010570-ytv7dwr0	216	8	are	be	VBP
cord-010570-ytv7dwr0	216	9	protective	protective	JJ
cord-010570-ytv7dwr0	216	10	,	,	,
cord-010570-ytv7dwr0	216	11	nonprotective	nonprotective	JJ
cord-010570-ytv7dwr0	216	12	,	,	,
cord-010570-ytv7dwr0	216	13	and	and	CC
cord-010570-ytv7dwr0	216	14	deleterious	deleterious	JJ
cord-010570-ytv7dwr0	216	15	antibodies	antibody	NNS
cord-010570-ytv7dwr0	216	16	to	to	IN
cord-010570-ytv7dwr0	216	17	the	the	DT
cord-010570-ytv7dwr0	216	18	C.	C.	NNP
cord-010570-ytv7dwr0	216	19	neoformans	neoformans	NNP
cord-010570-ytv7dwr0	216	20	capsule	capsule	NN
cord-010570-ytv7dwr0	216	21	polysaccharide	polysaccharide	NN
cord-010570-ytv7dwr0	216	22	[	[	-LRB-
cord-010570-ytv7dwr0	216	23	136	136	CD
cord-010570-ytv7dwr0	216	24	]	]	-RRB-
cord-010570-ytv7dwr0	216	25	.	.	.
cord-010570-ytv7dwr0	217	1	Heavy	heavy	JJ
cord-010570-ytv7dwr0	217	2	chain	chain	NN
cord-010570-ytv7dwr0	217	3	isotype	isotype	NN
cord-010570-ytv7dwr0	217	4	[	[	-LRB-
cord-010570-ytv7dwr0	217	5	136	136	CD
cord-010570-ytv7dwr0	217	6	,	,	,
cord-010570-ytv7dwr0	217	7	140	140	CD
cord-010570-ytv7dwr0	217	8	]	]	-RRB-
cord-010570-ytv7dwr0	217	9	and	and	CC
cord-010570-ytv7dwr0	217	10	epitope	epitope	NN
cord-010570-ytv7dwr0	217	11	specificity	specificity	NN
cord-010570-ytv7dwr0	217	12	[	[	-LRB-
cord-010570-ytv7dwr0	217	13	141	141	CD
cord-010570-ytv7dwr0	217	14	]	]	-RRB-
cord-010570-ytv7dwr0	217	15	are	be	VBP
cord-010570-ytv7dwr0	217	16	important	important	JJ
cord-010570-ytv7dwr0	217	17	determinants	determinant	NNS
cord-010570-ytv7dwr0	217	18	of	of	IN
cord-010570-ytv7dwr0	217	19	protective	protective	JJ
cord-010570-ytv7dwr0	217	20	efficacy	efficacy	NN
cord-010570-ytv7dwr0	217	21	.	.	.
cord-010570-ytv7dwr0	218	1	The	the	DT
cord-010570-ytv7dwr0	218	2	existence	existence	NN
cord-010570-ytv7dwr0	218	3	of	of	IN
cord-010570-ytv7dwr0	218	4	protective	protective	JJ
cord-010570-ytv7dwr0	218	5	and	and	CC
cord-010570-ytv7dwr0	218	6	nonprotective	nonprotective	JJ
cord-010570-ytv7dwr0	218	7	antibodies	antibody	NNS
cord-010570-ytv7dwr0	218	8	against	against	IN
cord-010570-ytv7dwr0	218	9	C.	C.	NNP
cord-010570-ytv7dwr0	218	10	neoformans	neoformans	NNP
cord-010570-ytv7dwr0	218	11	,	,	,
cord-010570-ytv7dwr0	218	12	a	a	DT
cord-010570-ytv7dwr0	218	13	fungus	fungus	NN
cord-010570-ytv7dwr0	218	14	for	for	IN
cord-010570-ytv7dwr0	218	15	which	which	WDT
cord-010570-ytv7dwr0	218	16	antibody	antibody	NN
cord-010570-ytv7dwr0	218	17	immunity	immunity	NN
cord-010570-ytv7dwr0	218	18	mayor	mayor	NN
cord-010570-ytv7dwr0	218	19	may	may	MD
cord-010570-ytv7dwr0	218	20	not	not	RB
cord-010570-ytv7dwr0	218	21	be	be	VB
cord-010570-ytv7dwr0	218	22	important	important	JJ
cord-010570-ytv7dwr0	218	23	,	,	,
cord-010570-ytv7dwr0	218	24	provides	provide	VBZ
cord-010570-ytv7dwr0	218	25	a	a	DT
cord-010570-ytv7dwr0	218	26	paradigm	paradigm	NN
cord-010570-ytv7dwr0	218	27	that	that	WDT
cord-010570-ytv7dwr0	218	28	may	may	MD
cord-010570-ytv7dwr0	218	29	be	be	VB
cord-010570-ytv7dwr0	218	30	applicable	applicable	JJ
cord-010570-ytv7dwr0	218	31	to	to	IN
cord-010570-ytv7dwr0	218	32	other	other	JJ
cord-010570-ytv7dwr0	218	33	pathogens	pathogen	NNS
cord-010570-ytv7dwr0	218	34	.	.	.
cord-010570-ytv7dwr0	219	1	We	-PRON-	PRP
cord-010570-ytv7dwr0	219	2	propose	propose	VBP
cord-010570-ytv7dwr0	219	3	the	the	DT
cord-010570-ytv7dwr0	219	4	hypothesis	hypothesis	NN
cord-010570-ytv7dwr0	219	5	that	that	IN
cord-010570-ytv7dwr0	219	6	for	for	IN
cord-010570-ytv7dwr0	219	7	every	every	DT
cord-010570-ytv7dwr0	219	8	pathogen	pathogen	NN
cord-010570-ytv7dwr0	219	9	there	there	EX
cord-010570-ytv7dwr0	219	10	exists	exist	VBZ
cord-010570-ytv7dwr0	219	11	an	an	DT
cord-010570-ytv7dwr0	219	12	antibody	antibody	NN
cord-010570-ytv7dwr0	219	13	that	that	WDT
cord-010570-ytv7dwr0	219	14	will	will	MD
cord-010570-ytv7dwr0	219	15	modify	modify	VB
cord-010570-ytv7dwr0	219	16	the	the	DT
cord-010570-ytv7dwr0	219	17	course	course	NN
cord-010570-ytv7dwr0	219	18	of	of	IN
cord-010570-ytv7dwr0	219	19	infection	infection	NN
cord-010570-ytv7dwr0	219	20	to	to	IN
cord-010570-ytv7dwr0	219	21	the	the	DT
cord-010570-ytv7dwr0	219	22	benefit	benefit	NN
cord-010570-ytv7dwr0	219	23	of	of	IN
cord-010570-ytv7dwr0	219	24	the	the	DT
cord-010570-ytv7dwr0	219	25	host	host	NN
cord-010570-ytv7dwr0	219	26	;	;	:
cord-010570-ytv7dwr0	219	27	such	such	JJ
cord-010570-ytv7dwr0	219	28	antibodies	antibody	NNS
cord-010570-ytv7dwr0	219	29	are	be	VBP
cord-010570-ytv7dwr0	219	30	candidates	candidate	NNS
cord-010570-ytv7dwr0	219	31	for	for	IN
cord-010570-ytv7dwr0	219	32	development	development	NN
cord-010570-ytv7dwr0	219	33	as	as	IN
cord-010570-ytv7dwr0	219	34	antimicrobial	antimicrobial	JJ
cord-010570-ytv7dwr0	219	35	drugs	drug	NNS
cord-010570-ytv7dwr0	219	36	.	.	.
cord-010570-ytv7dwr0	220	1	Our	-PRON-	PRP$
cord-010570-ytv7dwr0	220	2	proposal	proposal	NN
cord-010570-ytv7dwr0	220	3	includes	include	VBZ
cord-010570-ytv7dwr0	220	4	the	the	DT
cord-010570-ytv7dwr0	220	5	use	use	NN
cord-010570-ytv7dwr0	220	6	of	of	IN
cord-010570-ytv7dwr0	220	7	antibodies	antibody	NNS
cord-010570-ytv7dwr0	220	8	for	for	IN
cord-010570-ytv7dwr0	220	9	intracellular	intracellular	JJ
cord-010570-ytv7dwr0	220	10	pathogens	pathogen	NNS
cord-010570-ytv7dwr0	220	11	;	;	:
cord-010570-ytv7dwr0	220	12	for	for	IN
cord-010570-ytv7dwr0	220	13	example	example	NN
cord-010570-ytv7dwr0	220	14	,	,	,
cord-010570-ytv7dwr0	220	15	anti	anti	NNS
cord-010570-ytv7dwr0	220	16	-	-	NNS
cord-010570-ytv7dwr0	220	17	bodies	body	NNS
cord-010570-ytv7dwr0	220	18	may	may	MD
cord-010570-ytv7dwr0	220	19	exist	exist	VB
cord-010570-ytv7dwr0	220	20	that	that	WDT
cord-010570-ytv7dwr0	220	21	could	could	MD
cord-010570-ytv7dwr0	220	22	prevent	prevent	VB
cord-010570-ytv7dwr0	220	23	cell	cell	NN
cord-010570-ytv7dwr0	220	24	entry	entry	NN
cord-010570-ytv7dwr0	220	25	of	of	IN
cord-010570-ytv7dwr0	220	26	intracellular	intracellular	JJ
cord-010570-ytv7dwr0	220	27	bacteria	bacteria	NNS
cord-010570-ytv7dwr0	220	28	and/or	and/or	CC
cord-010570-ytv7dwr0	220	29	shift	shift	VB
cord-010570-ytv7dwr0	220	30	the	the	DT
cord-010570-ytv7dwr0	220	31	intracellular	intracellular	JJ
cord-010570-ytv7dwr0	220	32	location	location	NN
cord-010570-ytv7dwr0	220	33	of	of	IN
cord-010570-ytv7dwr0	220	34	such	such	JJ
cord-010570-ytv7dwr0	220	35	bacteria	bacteria	NNS
cord-010570-ytv7dwr0	220	36	by	by	IN
cord-010570-ytv7dwr0	220	37	promoting	promote	VBG
cord-010570-ytv7dwr0	220	38	internalization	internalization	NN
cord-010570-ytv7dwr0	220	39	through	through	IN
cord-010570-ytv7dwr0	220	40	Fe	Fe	NNP
cord-010570-ytv7dwr0	220	41	receptors	receptor	NNS
cord-010570-ytv7dwr0	220	42	.	.	.
cord-010570-ytv7dwr0	221	1	An	an	DT
cord-010570-ytv7dwr0	221	2	mAb	mab	NN
cord-010570-ytv7dwr0	221	3	that	that	WDT
cord-010570-ytv7dwr0	221	4	inhibits	inhibit	VBZ
cord-010570-ytv7dwr0	221	5	intracellular	intracellular	JJ
cord-010570-ytv7dwr0	221	6	Toxoplasma	toxoplasma	JJ
cord-010570-ytv7dwr0	221	7	gondii	gondii	NN
cord-010570-ytv7dwr0	221	8	infection	infection	NN
cord-010570-ytv7dwr0	221	9	has	have	VBZ
cord-010570-ytv7dwr0	221	10	recently	recently	RB
cord-010570-ytv7dwr0	221	11	been	be	VBN
cord-010570-ytv7dwr0	221	12	described	describe	VBN
cord-010570-ytv7dwr0	221	13	[	[	-LRB-
cord-010570-ytv7dwr0	221	14	142	142	CD
cord-010570-ytv7dwr0	221	15	]	]	-RRB-
cord-010570-ytv7dwr0	221	16	.	.	.
cord-010570-ytv7dwr0	222	1	In	in	IN
cord-010570-ytv7dwr0	222	2	addition	addition	NN
cord-010570-ytv7dwr0	222	3	,	,	,
cord-010570-ytv7dwr0	222	4	antibodies	antibody	NNS
cord-010570-ytv7dwr0	222	5	have	have	VBP
cord-010570-ytv7dwr0	222	6	been	be	VBN
cord-010570-ytv7dwr0	222	7	described	describe	VBN
cord-010570-ytv7dwr0	222	8	that	that	WDT
cord-010570-ytv7dwr0	222	9	can	can	MD
cord-010570-ytv7dwr0	222	10	neutralize	neutralize	VB
cord-010570-ytv7dwr0	222	11	viruses	virus	NNS
cord-010570-ytv7dwr0	222	12	intracellularly	intracellularly	JJ
cord-010570-ytv7dwr0	222	13	[	[	-LRB-
cord-010570-ytv7dwr0	222	14	143	143	CD
cord-010570-ytv7dwr0	222	15	]	]	-RRB-
cord-010570-ytv7dwr0	222	16	or	or	CC
cord-010570-ytv7dwr0	222	17	penetrate	penetrate	VB
cord-010570-ytv7dwr0	222	18	the	the	DT
cord-010570-ytv7dwr0	222	19	nuclear	nuclear	JJ
cord-010570-ytv7dwr0	222	20	membrane	membrane	NN
cord-010570-ytv7dwr0	222	21	[	[	-LRB-
cord-010570-ytv7dwr0	222	22	144	144	CD
cord-010570-ytv7dwr0	222	23	]	]	-RRB-
cord-010570-ytv7dwr0	222	24	.	.	.
cord-010570-ytv7dwr0	223	1	Our	-PRON-	PRP$
cord-010570-ytv7dwr0	223	2	proposal	proposal	NN
cord-010570-ytv7dwr0	223	3	is	be	VBZ
cord-010570-ytv7dwr0	223	4	not	not	RB
cord-010570-ytv7dwr0	223	5	limited	limited	JJ
cord-010570-ytv7dwr0	223	6	to	to	IN
cord-010570-ytv7dwr0	223	7	those	those	DT
cord-010570-ytv7dwr0	223	8	pathogens	pathogen	NNS
cord-010570-ytv7dwr0	223	9	for	for	IN
cord-010570-ytv7dwr0	223	10	which	which	WDT
cord-010570-ytv7dwr0	223	11	antibody	antibody	NN
cord-010570-ytv7dwr0	223	12	immunity	immunity	NN
cord-010570-ytv7dwr0	223	13	has	have	VBZ
cord-010570-ytv7dwr0	223	14	been	be	VBN
cord-010570-ytv7dwr0	223	15	demonstrated	demonstrate	VBN
cord-010570-ytv7dwr0	223	16	to	to	TO
cord-010570-ytv7dwr0	223	17	be	be	VB
cord-010570-ytv7dwr0	223	18	protective	protective	JJ
cord-010570-ytv7dwr0	223	19	.	.	.
cord-010570-ytv7dwr0	224	1	Conclusions	conclusion	NNS
cord-010570-ytv7dwr0	224	2	on	on	IN
cord-010570-ytv7dwr0	224	3	the	the	DT
cord-010570-ytv7dwr0	224	4	importance	importance	NN
cord-010570-ytv7dwr0	224	5	of	of	IN
cord-010570-ytv7dwr0	224	6	antibody	antibody	NN
cord-010570-ytv7dwr0	224	7	immunity	immunity	NN
cord-010570-ytv7dwr0	224	8	are	be	VBP
cord-010570-ytv7dwr0	224	9	usually	usually	RB
cord-010570-ytv7dwr0	224	10	based	base	VBN
cord-010570-ytv7dwr0	224	11	on	on	IN
cord-010570-ytv7dwr0	224	12	observations	observation	NNS
cord-010570-ytv7dwr0	224	13	made	make	VBN
cord-010570-ytv7dwr0	224	14	with	with	IN
cord-010570-ytv7dwr0	224	15	polyclonal	polyclonal	JJ
cord-010570-ytv7dwr0	224	16	sera	sera	NNP
cord-010570-ytv7dwr0	224	17	(	(	-LRB-
cord-010570-ytv7dwr0	224	18	i.e.	i.e.	FW
cord-010570-ytv7dwr0	224	19	,	,	,
cord-010570-ytv7dwr0	224	20	passive	passive	JJ
cord-010570-ytv7dwr0	224	21	protection	protection	NN
cord-010570-ytv7dwr0	224	22	or	or	CC
cord-010570-ytv7dwr0	224	23	correlation	correlation	NN
cord-010570-ytv7dwr0	224	24	of	of	IN
cord-010570-ytv7dwr0	224	25	immunity	immunity	NN
cord-010570-ytv7dwr0	224	26	with	with	IN
cord-010570-ytv7dwr0	224	27	the	the	DT
cord-010570-ytv7dwr0	224	28	presence	presence	NN
cord-010570-ytv7dwr0	224	29	of	of	IN
cord-010570-ytv7dwr0	224	30	antibody	antibody	NN
cord-010570-ytv7dwr0	224	31	)	)	-RRB-
cord-010570-ytv7dwr0	224	32	.	.	.
cord-010570-ytv7dwr0	225	1	Since	since	IN
cord-010570-ytv7dwr0	225	2	polyclonal	polyclonal	JJ
cord-010570-ytv7dwr0	225	3	sera	sera	NNP
cord-010570-ytv7dwr0	225	4	might	may	MD
cord-010570-ytv7dwr0	225	5	contain	contain	VB
cord-010570-ytv7dwr0	225	6	protective	protective	JJ
cord-010570-ytv7dwr0	225	7	antibodies	antibody	NNS
cord-010570-ytv7dwr0	225	8	,	,	,
cord-010570-ytv7dwr0	225	9	nonprotective	nonprotective	JJ
cord-010570-ytv7dwr0	225	10	antibodies	antibody	NNS
cord-010570-ytv7dwr0	225	11	,	,	,
cord-010570-ytv7dwr0	225	12	and	and	CC
cord-010570-ytv7dwr0	225	13	disease	disease	NN
cord-010570-ytv7dwr0	225	14	-	-	HYPH
cord-010570-ytv7dwr0	225	15	enhancing	enhance	VBG
cord-010570-ytv7dwr0	225	16	antibodies	antibody	NNS
cord-010570-ytv7dwr0	225	17	,	,	,
cord-010570-ytv7dwr0	225	18	the	the	DT
cord-010570-ytv7dwr0	225	19	existence	existence	NN
cord-010570-ytv7dwr0	225	20	of	of	IN
cord-010570-ytv7dwr0	225	21	protective	protective	JJ
cord-010570-ytv7dwr0	225	22	antibodies	antibody	NNS
cord-010570-ytv7dwr0	225	23	can	can	MD
cord-010570-ytv7dwr0	225	24	not	not	RB
cord-010570-ytv7dwr0	225	25	be	be	VB
cord-010570-ytv7dwr0	225	26	ruled	rule	VBN
cord-010570-ytv7dwr0	225	27	out	out	RP
cord-010570-ytv7dwr0	225	28	on	on	IN
cord-010570-ytv7dwr0	225	29	the	the	DT
cord-010570-ytv7dwr0	225	30	basis	basis	NN
cord-010570-ytv7dwr0	225	31	of	of	IN
cord-010570-ytv7dwr0	225	32	absence	absence	NN
cord-010570-ytv7dwr0	225	33	of	of	IN
cord-010570-ytv7dwr0	225	34	protection	protection	NN
cord-010570-ytv7dwr0	225	35	in	in	IN
cord-010570-ytv7dwr0	225	36	experiments	experiment	NNS
cord-010570-ytv7dwr0	225	37	involving	involve	VBG
cord-010570-ytv7dwr0	225	38	passive	passive	JJ
cord-010570-ytv7dwr0	225	39	transfer	transfer	NN
cord-010570-ytv7dwr0	225	40	of	of	IN
cord-010570-ytv7dwr0	225	41	polyclonal	polyclonal	JJ
cord-010570-ytv7dwr0	225	42	sera	sera	NNP
cord-010570-ytv7dwr0	225	43	or	or	CC
cord-010570-ytv7dwr0	225	44	immunizations	immunization	NNS
cord-010570-ytv7dwr0	225	45	.	.	.
cord-010570-ytv7dwr0	226	1	Conversely	conversely	RB
cord-010570-ytv7dwr0	226	2	,	,	,
cord-010570-ytv7dwr0	226	3	experiments	experiment	NNS
cord-010570-ytv7dwr0	226	4	that	that	WDT
cord-010570-ytv7dwr0	226	5	demonstrate	demonstrate	VBP
cord-010570-ytv7dwr0	226	6	that	that	IN
cord-010570-ytv7dwr0	226	7	polyclonal	polyclonal	JJ
cord-010570-ytv7dwr0	226	8	sera	sera	NNP
cord-010570-ytv7dwr0	226	9	can	can	MD
cord-010570-ytv7dwr0	226	10	mediate	mediate	VB
cord-010570-ytv7dwr0	226	11	protection	protection	NN
cord-010570-ytv7dwr0	226	12	indicate	indicate	VBP
cord-010570-ytv7dwr0	226	13	the	the	DT
cord-010570-ytv7dwr0	226	14	existence	existence	NN
cord-010570-ytv7dwr0	226	15	of	of	IN
cord-010570-ytv7dwr0	226	16	protective	protective	JJ
cord-010570-ytv7dwr0	226	17	antibodies	antibody	NNS
cord-010570-ytv7dwr0	226	18	.	.	.
cord-010570-ytv7dwr0	227	1	For	for	IN
cord-010570-ytv7dwr0	227	2	pathogens	pathogen	NNS
cord-010570-ytv7dwr0	227	3	for	for	IN
cord-010570-ytv7dwr0	227	4	which	which	WDT
cord-010570-ytv7dwr0	227	5	polyclonal	polyclonal	JJ
cord-010570-ytv7dwr0	227	6	antibody	antibody	NN
cord-010570-ytv7dwr0	227	7	has	have	VBZ
cord-010570-ytv7dwr0	227	8	shown	show	VBN
cord-010570-ytv7dwr0	227	9	no	no	DT
cord-010570-ytv7dwr0	227	10	protection	protection	NN
cord-010570-ytv7dwr0	227	11	,	,	,
cord-010570-ytv7dwr0	227	12	the	the	DT
cord-010570-ytv7dwr0	227	13	question	question	NN
cord-010570-ytv7dwr0	227	14	of	of	IN
cord-010570-ytv7dwr0	227	15	whether	whether	IN
cord-010570-ytv7dwr0	227	16	useful	useful	JJ
cord-010570-ytv7dwr0	227	17	antibodies	antibody	NNS
cord-010570-ytv7dwr0	227	18	exist	exist	VBP
cord-010570-ytv7dwr0	227	19	must	must	MD
cord-010570-ytv7dwr0	227	20	be	be	VB
cord-010570-ytv7dwr0	227	21	reevaluated	reevaluate	VBN
cord-010570-ytv7dwr0	227	22	with	with	IN
cord-010570-ytv7dwr0	227	23	mAbs	mabs	NN
cord-010570-ytv7dwr0	227	24	since	since	IN
cord-010570-ytv7dwr0	227	25	the	the	DT
cord-010570-ytv7dwr0	227	26	presence	presence	NN
cord-010570-ytv7dwr0	227	27	of	of	IN
cord-010570-ytv7dwr0	227	28	nonprotective	nonprotective	JJ
cord-010570-ytv7dwr0	227	29	or	or	CC
cord-010570-ytv7dwr0	227	30	deleterious	deleterious	JJ
cord-010570-ytv7dwr0	227	31	antibodies	antibody	NNS
cord-010570-ytv7dwr0	227	32	in	in	IN
cord-010570-ytv7dwr0	227	33	polyclonal	polyclonal	JJ
cord-010570-ytv7dwr0	227	34	sera	sera	NNP
cord-010570-ytv7dwr0	227	35	could	could	MD
cord-010570-ytv7dwr0	227	36	create	create	VB
cord-010570-ytv7dwr0	227	37	confounding	confounding	JJ
cord-010570-ytv7dwr0	227	38	variables	variable	NNS
cord-010570-ytv7dwr0	227	39	.	.	.
cord-010570-ytv7dwr0	228	1	A	a	DT
cord-010570-ytv7dwr0	228	2	corollary	corollary	NN
cord-010570-ytv7dwr0	228	3	of	of	IN
cord-010570-ytv7dwr0	228	4	our	-PRON-	PRP$
cord-010570-ytv7dwr0	228	5	proposal	proposal	NN
cord-010570-ytv7dwr0	228	6	is	be	VBZ
cord-010570-ytv7dwr0	228	7	that	that	IN
cord-010570-ytv7dwr0	228	8	antibody	antibody	NN
cord-010570-ytv7dwr0	228	9	-	-	HYPH
cord-010570-ytv7dwr0	228	10	based	base	VBN
cord-010570-ytv7dwr0	228	11	therapies	therapy	NNS
cord-010570-ytv7dwr0	228	12	may	may	MD
cord-010570-ytv7dwr0	228	13	be	be	VB
cord-010570-ytv7dwr0	228	14	developed	develop	VBN
cord-010570-ytv7dwr0	228	15	against	against	IN
cord-010570-ytv7dwr0	228	16	pathogens	pathogen	NNS
cord-010570-ytv7dwr0	228	17	for	for	IN
cord-010570-ytv7dwr0	228	18	which	which	WDT
cord-010570-ytv7dwr0	228	19	antibody	antibody	NN
cord-010570-ytv7dwr0	228	20	immunity	immunity	NN
cord-010570-ytv7dwr0	228	21	is	be	VBZ
cord-010570-ytv7dwr0	228	22	not	not	RB
cord-010570-ytv7dwr0	228	23	considered	consider	VBN
cord-010570-ytv7dwr0	228	24	to	to	TO
cord-010570-ytv7dwr0	228	25	be	be	VB
cord-010570-ytv7dwr0	228	26	important	important	JJ
cord-010570-ytv7dwr0	228	27	.	.	.
cord-010570-ytv7dwr0	229	1	Infections	infection	NNS
cord-010570-ytv7dwr0	229	2	that	that	WDT
cord-010570-ytv7dwr0	229	3	are	be	VBP
cord-010570-ytv7dwr0	229	4	difficult	difficult	JJ
cord-010570-ytv7dwr0	229	5	to	to	TO
cord-010570-ytv7dwr0	229	6	treat	treat	VB
cord-010570-ytv7dwr0	229	7	and	and	CC
cord-010570-ytv7dwr0	229	8	that	that	DT
cord-010570-ytv7dwr0	229	9	can	can	MD
cord-010570-ytv7dwr0	229	10	be	be	VB
cord-010570-ytv7dwr0	229	11	modified	modify	VBN
cord-010570-ytv7dwr0	229	12	by	by	IN
cord-010570-ytv7dwr0	229	13	antibody	antibody	NN
cord-010570-ytv7dwr0	229	14	immunity	immunity	NN
cord-010570-ytv7dwr0	229	15	provide	provide	VBP
cord-010570-ytv7dwr0	229	16	a	a	DT
cord-010570-ytv7dwr0	229	17	logical	logical	JJ
cord-010570-ytv7dwr0	229	18	starting	starting	NN
cord-010570-ytv7dwr0	229	19	point	point	NN
cord-010570-ytv7dwr0	229	20	for	for	IN
cord-010570-ytv7dwr0	229	21	the	the	DT
cord-010570-ytv7dwr0	229	22	development	development	NN
cord-010570-ytv7dwr0	229	23	of	of	IN
cord-010570-ytv7dwr0	229	24	antibody	antibody	NN
cord-010570-ytv7dwr0	229	25	-	-	HYPH
cord-010570-ytv7dwr0	229	26	based	base	VBN
cord-010570-ytv7dwr0	229	27	therapies	therapy	NNS
cord-010570-ytv7dwr0	229	28	.	.	.
cord-010570-ytv7dwr0	230	1	Antibodies	antibody	NNS
cord-010570-ytv7dwr0	230	2	have	have	VBP
cord-010570-ytv7dwr0	230	3	historically	historically	RB
cord-010570-ytv7dwr0	230	4	been	be	VBN
cord-010570-ytv7dwr0	230	5	more	more	RBR
cord-010570-ytv7dwr0	230	6	effective	effective	JJ
cord-010570-ytv7dwr0	230	7	in	in	IN
cord-010570-ytv7dwr0	230	8	prophylaxis	prophylaxis	NN
cord-010570-ytv7dwr0	230	9	than	than	IN
cord-010570-ytv7dwr0	230	10	in	in	IN
cord-010570-ytv7dwr0	230	11	therapy	therapy	NN
cord-010570-ytv7dwr0	230	12	.	.	.
cord-010570-ytv7dwr0	231	1	Antibody	antibody	NN
cord-010570-ytv7dwr0	231	2	-	-	HYPH
cord-010570-ytv7dwr0	231	3	based	base	VBN
cord-010570-ytv7dwr0	231	4	therapies	therapy	NNS
cord-010570-ytv7dwr0	231	5	have	have	VBP
cord-010570-ytv7dwr0	231	6	traditionally	traditionally	RB
cord-010570-ytv7dwr0	231	7	been	be	VBN
cord-010570-ytv7dwr0	231	8	most	most	RBS
cord-010570-ytv7dwr0	231	9	effective	effective	JJ
cord-010570-ytv7dwr0	231	10	in	in	IN
cord-010570-ytv7dwr0	231	11	infections	infection	NNS
cord-010570-ytv7dwr0	231	12	where	where	WRB
cord-010570-ytv7dwr0	231	13	viral	viral	JJ
cord-010570-ytv7dwr0	231	14	and	and	CC
cord-010570-ytv7dwr0	231	15	toxin	toxin	NN
cord-010570-ytv7dwr0	231	16	neutralization	neutralization	NN
cord-010570-ytv7dwr0	231	17	modifies	modify	VBZ
cord-010570-ytv7dwr0	231	18	the	the	DT
cord-010570-ytv7dwr0	231	19	course	course	NN
cord-010570-ytv7dwr0	231	20	of	of	IN
cord-010570-ytv7dwr0	231	21	the	the	DT
cord-010570-ytv7dwr0	231	22	disease	disease	NN
cord-010570-ytv7dwr0	231	23	.	.	.
cord-010570-ytv7dwr0	232	1	However	however	RB
cord-010570-ytv7dwr0	232	2	,	,	,
cord-010570-ytv7dwr0	232	3	most	most	JJS
cord-010570-ytv7dwr0	232	4	of	of	IN
cord-010570-ytv7dwr0	232	5	the	the	DT
cord-010570-ytv7dwr0	232	6	historical	historical	JJ
cord-010570-ytv7dwr0	232	7	experience	experience	NN
cord-010570-ytv7dwr0	232	8	was	be	VBD
cord-010570-ytv7dwr0	232	9	gained	gain	VBN
cord-010570-ytv7dwr0	232	10	with	with	IN
cord-010570-ytv7dwr0	232	11	polyclonal	polyclonal	JJ
cord-010570-ytv7dwr0	232	12	preparations	preparation	NNS
cord-010570-ytv7dwr0	232	13	of	of	IN
cord-010570-ytv7dwr0	232	14	uncertain	uncertain	JJ
cord-010570-ytv7dwr0	232	15	composition	composition	NN
cord-010570-ytv7dwr0	232	16	and	and	CC
cord-010570-ytv7dwr0	232	17	mayor	mayor	NN
cord-010570-ytv7dwr0	232	18	may	may	MD
cord-010570-ytv7dwr0	232	19	not	not	RB
cord-010570-ytv7dwr0	232	20	be	be	VB
cord-010570-ytv7dwr0	232	21	applicable	applicable	JJ
cord-010570-ytv7dwr0	232	22	to	to	IN
cord-010570-ytv7dwr0	232	23	mAb	mab	JJ
cord-010570-ytv7dwr0	232	24	preparations	preparation	NNS
cord-010570-ytv7dwr0	232	25	with	with	IN
cord-010570-ytv7dwr0	232	26	high	high	JJ
cord-010570-ytv7dwr0	232	27	activity	activity	NN
cord-010570-ytv7dwr0	232	28	.	.	.
cord-010570-ytv7dwr0	233	1	Opportunistic	opportunistic	JJ
cord-010570-ytv7dwr0	233	2	infections	infection	NNS
cord-010570-ytv7dwr0	233	3	.	.	.
cord-010570-ytv7dwr0	234	1	Infections	infection	NNS
cord-010570-ytv7dwr0	234	2	with	with	IN
cord-010570-ytv7dwr0	234	3	low	low	JJ
cord-010570-ytv7dwr0	234	4	-	-	HYPH
cord-010570-ytv7dwr0	234	5	virulence	virulence	NN
cord-010570-ytv7dwr0	234	6	organisms	organism	NNS
cord-010570-ytv7dwr0	234	7	in	in	IN
cord-010570-ytv7dwr0	234	8	immunosuppressed	immunosuppressed	JJ
cord-010570-ytv7dwr0	234	9	individuals	individual	NNS
cord-010570-ytv7dwr0	234	10	are	be	VBP
cord-010570-ytv7dwr0	234	11	often	often	RB
cord-010570-ytv7dwr0	234	12	difficult	difficult	JJ
cord-010570-ytv7dwr0	234	13	to	to	TO
cord-010570-ytv7dwr0	234	14	treat	treat	VB
cord-010570-ytv7dwr0	234	15	and	and	CC
cord-010570-ytv7dwr0	234	16	are	be	VBP
cord-010570-ytv7dwr0	234	17	sometimes	sometimes	RB
cord-010570-ytv7dwr0	234	18	incurable	incurable	JJ
cord-010570-ytv7dwr0	234	19	.	.	.
cord-010570-ytv7dwr0	235	1	Since	since	IN
cord-010570-ytv7dwr0	235	2	the	the	DT
cord-010570-ytv7dwr0	235	3	problem	problem	NN
cord-010570-ytv7dwr0	235	4	is	be	VBZ
cord-010570-ytv7dwr0	235	5	deficient	deficient	JJ
cord-010570-ytv7dwr0	235	6	immunity	immunity	NN
cord-010570-ytv7dwr0	235	7	,	,	,
cord-010570-ytv7dwr0	235	8	antibody	antibody	NN
cord-010570-ytv7dwr0	235	9	therapy	therapy	NN
cord-010570-ytv7dwr0	235	10	is	be	VBZ
cord-010570-ytv7dwr0	235	11	an	an	DT
cord-010570-ytv7dwr0	235	12	attractive	attractive	JJ
cord-010570-ytv7dwr0	235	13	option	option	NN
cord-010570-ytv7dwr0	235	14	because	because	IN
cord-010570-ytv7dwr0	235	15	antibodies	antibody	NNS
cord-010570-ytv7dwr0	235	16	can	can	MD
cord-010570-ytv7dwr0	235	17	enhance	enhance	VB
cord-010570-ytv7dwr0	235	18	immune	immune	JJ
cord-010570-ytv7dwr0	235	19	function	function	NN
cord-010570-ytv7dwr0	235	20	.	.	.
cord-010570-ytv7dwr0	236	1	Table	table	NN
cord-010570-ytv7dwr0	236	2	2	2	CD
cord-010570-ytv7dwr0	236	3	lists	list	VBZ
cord-010570-ytv7dwr0	236	4	examples	example	NNS
cord-010570-ytv7dwr0	236	5	of	of	IN
cord-010570-ytv7dwr0	236	6	opportunistic	opportunistic	JJ
cord-010570-ytv7dwr0	236	7	pathogens	pathogen	NNS
cord-010570-ytv7dwr0	236	8	for	for	IN
cord-010570-ytv7dwr0	236	9	which	which	WDT
cord-010570-ytv7dwr0	236	10	antibody	antibody	NN
cord-010570-ytv7dwr0	236	11	can	can	MD
cord-010570-ytv7dwr0	236	12	modify	modify	VB
cord-010570-ytv7dwr0	236	13	the	the	DT
cord-010570-ytv7dwr0	236	14	course	course	NN
cord-010570-ytv7dwr0	236	15	of	of	IN
cord-010570-ytv7dwr0	236	16	infection	infection	NN
cord-010570-ytv7dwr0	236	17	.	.	.
cord-010570-ytv7dwr0	237	1	Antibiotic	antibiotic	JJ
cord-010570-ytv7dwr0	237	2	resistance	resistance	NN
cord-010570-ytv7dwr0	237	3	.	.	.
cord-010570-ytv7dwr0	238	1	Drug	drug	NN
cord-010570-ytv7dwr0	238	2	-	-	HYPH
cord-010570-ytv7dwr0	238	3	resistant	resistant	JJ
cord-010570-ytv7dwr0	238	4	organisms	organism	NNS
cord-010570-ytv7dwr0	238	5	are	be	VBP
cord-010570-ytv7dwr0	238	6	targets	target	NNS
cord-010570-ytv7dwr0	238	7	for	for	IN
cord-010570-ytv7dwr0	238	8	development	development	NN
cord-010570-ytv7dwr0	238	9	of	of	IN
cord-010570-ytv7dwr0	238	10	antibody	antibody	NN
cord-010570-ytv7dwr0	238	11	-	-	HYPH
cord-010570-ytv7dwr0	238	12	based	base	VBN
cord-010570-ytv7dwr0	238	13	therapies	therapy	NNS
cord-010570-ytv7dwr0	238	14	.	.	.
cord-010570-ytv7dwr0	239	1	The	the	DT
cord-010570-ytv7dwr0	239	2	spread	spread	NN
cord-010570-ytv7dwr0	239	3	of	of	IN
cord-010570-ytv7dwr0	239	4	penicillin	penicillin	NN
cord-010570-ytv7dwr0	239	5	-	-	HYPH
cord-010570-ytv7dwr0	239	6	resistant	resistant	JJ
cord-010570-ytv7dwr0	239	7	S.pneumoniae	S.pneumoniae	NNS
cord-010570-ytv7dwr0	239	8	,	,	,
cord-010570-ytv7dwr0	239	9	methicillin	methicillin	NN
cord-010570-ytv7dwr0	239	10	-	-	HYPH
cord-010570-ytv7dwr0	239	11	resistant	resistant	JJ
cord-010570-ytv7dwr0	239	12	Staphylococcus	Staphylococcus	NNP
cord-010570-ytv7dwr0	239	13	aureus	aureus	NN
cord-010570-ytv7dwr0	239	14	,	,	,
cord-010570-ytv7dwr0	239	15	and	and	CC
cord-010570-ytv7dwr0	239	16	multiply	multiply	VB
cord-010570-ytv7dwr0	239	17	-	-	HYPH
cord-010570-ytv7dwr0	239	18	drug	drug	NN
cord-010570-ytv7dwr0	239	19	-	-	HYPH
cord-010570-ytv7dwr0	239	20	resistant	resistant	JJ
cord-010570-ytv7dwr0	239	21	E.	E.	NNP
cord-010570-ytv7dwr0	239	22	faecium	faecium	NN
cord-010570-ytv7dwr0	239	23	has	have	VBZ
cord-010570-ytv7dwr0	239	24	limited	limit	VBN
cord-010570-ytv7dwr0	239	25	the	the	DT
cord-010570-ytv7dwr0	239	26	useful	useful	JJ
cord-010570-ytv7dwr0	239	27	antibiotic	antibiotic	JJ
cord-010570-ytv7dwr0	239	28	arsenal	arsenal	NN
cord-010570-ytv7dwr0	239	29	against	against	IN
cord-010570-ytv7dwr0	239	30	these	these	DT
cord-010570-ytv7dwr0	239	31	pathogens	pathogen	NNS
cord-010570-ytv7dwr0	239	32	[	[	-LRB-
cord-010570-ytv7dwr0	239	33	4	4	CD
cord-010570-ytv7dwr0	239	34	,	,	,
cord-010570-ytv7dwr0	239	35	6	6	CD
cord-010570-ytv7dwr0	239	36	,	,	,
cord-010570-ytv7dwr0	239	37	153	153	CD
cord-010570-ytv7dwr0	239	38	]	]	-RRB-
cord-010570-ytv7dwr0	239	39	.	.	.
cord-010570-ytv7dwr0	240	1	For	for	IN
cord-010570-ytv7dwr0	240	2	pneumococcus	pneumococcus	NNP
cord-010570-ytv7dwr0	240	3	,	,	,
cord-010570-ytv7dwr0	240	4	antibody	antibody	NN
cord-010570-ytv7dwr0	240	5	therapy	therapy	NN
cord-010570-ytv7dwr0	240	6	has	have	VBZ
cord-010570-ytv7dwr0	240	7	been	be	VBN
cord-010570-ytv7dwr0	240	8	shown	show	VBN
cord-010570-ytv7dwr0	240	9	to	to	TO
cord-010570-ytv7dwr0	240	10	be	be	VB
cord-010570-ytv7dwr0	240	11	useful	useful	JJ
cord-010570-ytv7dwr0	240	12	[	[	-LRB-
cord-010570-ytv7dwr0	240	13	7	7	CD
cord-010570-ytv7dwr0	240	14	]	]	-RRB-
cord-010570-ytv7dwr0	240	15	.	.	.
cord-010570-ytv7dwr0	241	1	Antibody	antibody	NN
cord-010570-ytv7dwr0	241	2	may	may	MD
cord-010570-ytv7dwr0	241	3	be	be	VB
cord-010570-ytv7dwr0	241	4	useful	useful	JJ
cord-010570-ytv7dwr0	241	5	against	against	IN
cord-010570-ytv7dwr0	241	6	staphylococcal	staphylococcal	JJ
cord-010570-ytv7dwr0	241	7	infection	infection	NN
cord-010570-ytv7dwr0	241	8	[	[	-LRB-
cord-010570-ytv7dwr0	241	9	154	154	CD
cord-010570-ytv7dwr0	241	10	,	,	,
cord-010570-ytv7dwr0	241	11	155	155	CD
cord-010570-ytv7dwr0	241	12	]	]	-RRB-
cord-010570-ytv7dwr0	241	13	.	.	.
cord-010570-ytv7dwr0	242	1	For	for	IN
cord-010570-ytv7dwr0	242	2	E.faecium	e.faecium	NN
cord-010570-ytv7dwr0	242	3	,	,	,
cord-010570-ytv7dwr0	242	4	the	the	DT
cord-010570-ytv7dwr0	242	5	role	role	NN
cord-010570-ytv7dwr0	242	6	of	of	IN
cord-010570-ytv7dwr0	242	7	antibody	antibody	NN
cord-010570-ytv7dwr0	242	8	immu	immu	NNP
cord-010570-ytv7dwr0	242	9	-	-	HYPH
cord-010570-ytv7dwr0	242	10	ern	ern	NNP
cord-010570-ytv7dwr0	242	11	1995;21	1995;21	NNP
cord-010570-ytv7dwr0	242	12	(	(	-LRB-
cord-010570-ytv7dwr0	242	13	July	July	NNP
cord-010570-ytv7dwr0	242	14	)	)	-RRB-
cord-010570-ytv7dwr0	242	15	Table	table	NN
cord-010570-ytv7dwr0	242	16	2	2	CD
cord-010570-ytv7dwr0	242	17	.	.	.
cord-010570-ytv7dwr0	243	1	Opportunistic	opportunistic	JJ
cord-010570-ytv7dwr0	243	2	pathogens	pathogen	NNS
cord-010570-ytv7dwr0	243	3	for	for	IN
cord-010570-ytv7dwr0	243	4	which	which	WDT
cord-010570-ytv7dwr0	243	5	experimental	experimental	JJ
cord-010570-ytv7dwr0	243	6	data	datum	NNS
cord-010570-ytv7dwr0	243	7	suggest	suggest	VBP
cord-010570-ytv7dwr0	243	8	a	a	DT
cord-010570-ytv7dwr0	243	9	potential	potential	JJ
cord-010570-ytv7dwr0	243	10	role	role	NN
cord-010570-ytv7dwr0	243	11	for	for	IN
cord-010570-ytv7dwr0	243	12	antibody	antibody	NN
cord-010570-ytv7dwr0	243	13	-	-	HYPH
cord-010570-ytv7dwr0	243	14	based	base	VBN
cord-010570-ytv7dwr0	243	15	therapies	therapy	NNS
cord-010570-ytv7dwr0	243	16	.	.	.
cord-010570-ytv7dwr0	244	1	nity	nity	NNP
cord-010570-ytv7dwr0	244	2	is	be	VBZ
cord-010570-ytv7dwr0	244	3	uncertain	uncertain	JJ
cord-010570-ytv7dwr0	244	4	,	,	,
cord-010570-ytv7dwr0	244	5	but	but	CC
cord-010570-ytv7dwr0	244	6	some	some	DT
cord-010570-ytv7dwr0	244	7	patients	patient	NNS
cord-010570-ytv7dwr0	244	8	make	make	VBP
cord-010570-ytv7dwr0	244	9	opsonic	opsonic	JJ
cord-010570-ytv7dwr0	244	10	antibodies	antibody	NNS
cord-010570-ytv7dwr0	244	11	,	,	,
cord-010570-ytv7dwr0	244	12	which	which	WDT
cord-010570-ytv7dwr0	244	13	might	may	MD
cord-010570-ytv7dwr0	244	14	be	be	VB
cord-010570-ytv7dwr0	244	15	protective	protective	JJ
cord-010570-ytv7dwr0	244	16	[	[	-LRB-
cord-010570-ytv7dwr0	244	17	156	156	CD
cord-010570-ytv7dwr0	244	18	]	]	-RRB-
cord-010570-ytv7dwr0	244	19	.	.	.
cord-010570-ytv7dwr0	245	1	Significant	significant	JJ
cord-010570-ytv7dwr0	245	2	work	work	NN
cord-010570-ytv7dwr0	245	3	has	have	VBZ
cord-010570-ytv7dwr0	245	4	already	already	RB
cord-010570-ytv7dwr0	245	5	been	be	VBN
cord-010570-ytv7dwr0	245	6	done	do	VBN
cord-010570-ytv7dwr0	245	7	in	in	IN
cord-010570-ytv7dwr0	245	8	the	the	DT
cord-010570-ytv7dwr0	245	9	development	development	NN
cord-010570-ytv7dwr0	245	10	of	of	IN
cord-010570-ytv7dwr0	245	11	pseudomonal	pseudomonal	JJ
cord-010570-ytv7dwr0	245	12	antibodies	antibody	NNS
cord-010570-ytv7dwr0	245	13	for	for	IN
cord-010570-ytv7dwr0	245	14	resistant	resistant	JJ
cord-010570-ytv7dwr0	245	15	gram	gram	JJ
cord-010570-ytv7dwr0	245	16	-	-	HYPH
cord-010570-ytv7dwr0	245	17	negative	negative	JJ
cord-010570-ytv7dwr0	245	18	organisms	organism	NNS
cord-010570-ytv7dwr0	245	19	(	(	-LRB-
cord-010570-ytv7dwr0	245	20	table	table	NN
cord-010570-ytv7dwr0	245	21	2	2	CD
cord-010570-ytv7dwr0	245	22	)	)	-RRB-
cord-010570-ytv7dwr0	245	23	.	.	.
cord-010570-ytv7dwr0	246	1	The	the	DT
cord-010570-ytv7dwr0	246	2	addition	addition	NN
cord-010570-ytv7dwr0	246	3	of	of	IN
cord-010570-ytv7dwr0	246	4	antibody	antibody	NN
cord-010570-ytv7dwr0	246	5	-	-	HYPH
cord-010570-ytv7dwr0	246	6	based	base	VBN
cord-010570-ytv7dwr0	246	7	therapies	therapy	NNS
cord-010570-ytv7dwr0	246	8	to	to	IN
cord-010570-ytv7dwr0	246	9	chemotherapy	chemotherapy	NN
cord-010570-ytv7dwr0	246	10	may	may	MD
cord-010570-ytv7dwr0	246	11	slow	slow	VB
cord-010570-ytv7dwr0	246	12	the	the	DT
cord-010570-ytv7dwr0	246	13	development	development	NN
cord-010570-ytv7dwr0	246	14	of	of	IN
cord-010570-ytv7dwr0	246	15	resistance	resistance	NN
cord-010570-ytv7dwr0	246	16	and	and	CC
cord-010570-ytv7dwr0	246	17	improve	improve	VB
cord-010570-ytv7dwr0	246	18	outcome	outcome	NN
cord-010570-ytv7dwr0	246	19	.	.	.
cord-010570-ytv7dwr0	247	1	Toxin	toxin	NN
cord-010570-ytv7dwr0	247	2	neutralization	neutralization	NN
cord-010570-ytv7dwr0	247	3	.	.	.
cord-010570-ytv7dwr0	248	1	The	the	DT
cord-010570-ytv7dwr0	248	2	ability	ability	NN
cord-010570-ytv7dwr0	248	3	to	to	TO
cord-010570-ytv7dwr0	248	4	neutralize	neutralize	VB
cord-010570-ytv7dwr0	248	5	toxins	toxin	NNS
cord-010570-ytv7dwr0	248	6	is	be	VBZ
cord-010570-ytv7dwr0	248	7	a	a	DT
cord-010570-ytv7dwr0	248	8	unique	unique	JJ
cord-010570-ytv7dwr0	248	9	characteristic	characteristic	JJ
cord-010570-ytv7dwr0	248	10	ofantibody	ofantibody	NN
cord-010570-ytv7dwr0	248	11	-	-	HYPH
cord-010570-ytv7dwr0	248	12	based	base	VBN
cord-010570-ytv7dwr0	248	13	therapies	therapy	NNS
cord-010570-ytv7dwr0	248	14	.	.	.
cord-010570-ytv7dwr0	249	1	Antitoxin	antitoxin	NN
cord-010570-ytv7dwr0	249	2	antibodies	antibody	NNS
cord-010570-ytv7dwr0	249	3	are	be	VBP
cord-010570-ytv7dwr0	249	4	useful	useful	JJ
cord-010570-ytv7dwr0	249	5	for	for	IN
cord-010570-ytv7dwr0	249	6	the	the	DT
cord-010570-ytv7dwr0	249	7	treatment	treatment	NN
cord-010570-ytv7dwr0	249	8	of	of	IN
cord-010570-ytv7dwr0	249	9	diphtheria	diphtheria	NN
cord-010570-ytv7dwr0	249	10	,	,	,
cord-010570-ytv7dwr0	249	11	tetanus	tetanus	NN
cord-010570-ytv7dwr0	249	12	,	,	,
cord-010570-ytv7dwr0	249	13	botulism	botulism	NN
cord-010570-ytv7dwr0	249	14	,	,	,
cord-010570-ytv7dwr0	249	15	snake	snake	NN
cord-010570-ytv7dwr0	249	16	bites	bite	NNS
cord-010570-ytv7dwr0	249	17	,	,	,
cord-010570-ytv7dwr0	249	18	and	and	CC
cord-010570-ytv7dwr0	249	19	black	black	JJ
cord-010570-ytv7dwr0	249	20	widow	widow	NN
cord-010570-ytv7dwr0	249	21	bites	bite	NNS
cord-010570-ytv7dwr0	249	22	(	(	-LRB-
cord-010570-ytv7dwr0	249	23	see	see	VB
cord-010570-ytv7dwr0	249	24	above	above	RB
cord-010570-ytv7dwr0	249	25	)	)	-RRB-
cord-010570-ytv7dwr0	249	26	.	.	.
cord-010570-ytv7dwr0	250	1	Recent	recent	JJ
cord-010570-ytv7dwr0	250	2	attempts	attempt	NNS
cord-010570-ytv7dwr0	250	3	to	to	TO
cord-010570-ytv7dwr0	250	4	develop	develop	VB
cord-010570-ytv7dwr0	250	5	antibody	antibody	NN
cord-010570-ytv7dwr0	250	6	therapy	therapy	NN
cord-010570-ytv7dwr0	250	7	for	for	IN
cord-010570-ytv7dwr0	250	8	gram	gram	NN
cord-010570-ytv7dwr0	250	9	-	-	HYPH
cord-010570-ytv7dwr0	250	10	negative	negative	JJ
cord-010570-ytv7dwr0	250	11	sepsis	sepsis	NN
cord-010570-ytv7dwr0	250	12	have	have	VBP
cord-010570-ytv7dwr0	250	13	focused	focus	VBN
cord-010570-ytv7dwr0	250	14	on	on	IN
cord-010570-ytv7dwr0	250	15	mAbs	mAbs	NNP
cord-010570-ytv7dwr0	250	16	to	to	TO
cord-010570-ytv7dwr0	250	17	neutralize	neutralize	VB
cord-010570-ytv7dwr0	250	18	endotoxin	endotoxin	NN
cord-010570-ytv7dwr0	250	19	[	[	-LRB-
cord-010570-ytv7dwr0	250	20	123	123	CD
cord-010570-ytv7dwr0	250	21	,	,	,
cord-010570-ytv7dwr0	250	22	157	157	CD
cord-010570-ytv7dwr0	250	23	,	,	,
cord-010570-ytv7dwr0	250	24	158	158	CD
cord-010570-ytv7dwr0	250	25	]	]	-RRB-
cord-010570-ytv7dwr0	250	26	and	and	CC
cord-010570-ytv7dwr0	250	27	cytokines	cytokine	NNS
cord-010570-ytv7dwr0	250	28	[	[	-LRB-
cord-010570-ytv7dwr0	250	29	159	159	CD
cord-010570-ytv7dwr0	250	30	]	]	-RRB-
cord-010570-ytv7dwr0	250	31	.	.	.
cord-010570-ytv7dwr0	251	1	Pseudomonas	Pseudomonas	NNP
cord-010570-ytv7dwr0	251	2	aeruginosa	aeruginosa	NN
cord-010570-ytv7dwr0	251	3	sepsis	sepsis	NN
cord-010570-ytv7dwr0	251	4	,	,	,
cord-010570-ytv7dwr0	251	5	combination	combination	NN
cord-010570-ytv7dwr0	251	6	therapy	therapy	NN
cord-010570-ytv7dwr0	251	7	with	with	IN
cord-010570-ytv7dwr0	251	8	mAbs	mAbs	NNP
cord-010570-ytv7dwr0	251	9	to	to	TO
cord-010570-ytv7dwr0	251	10	endotoxin	endotoxin	VB
cord-010570-ytv7dwr0	251	11	and	and	CC
cord-010570-ytv7dwr0	251	12	tumor	tumor	NN
cord-010570-ytv7dwr0	251	13	necrosis	necrosis	NN
cord-010570-ytv7dwr0	251	14	factor	factor	NN
cord-010570-ytv7dwr0	251	15	was	be	VBD
cord-010570-ytv7dwr0	251	16	superior	superior	JJ
cord-010570-ytv7dwr0	251	17	to	to	IN
cord-010570-ytv7dwr0	251	18	therapy	therapy	NN
cord-010570-ytv7dwr0	251	19	with	with	IN
cord-010570-ytv7dwr0	251	20	a	a	DT
cord-010570-ytv7dwr0	251	21	single	single	JJ
cord-010570-ytv7dwr0	251	22	mAb	mAb	NNS
cord-010570-ytv7dwr0	251	23	[	[	-LRB-
cord-010570-ytv7dwr0	251	24	160	160	CD
cord-010570-ytv7dwr0	251	25	]	]	-RRB-
cord-010570-ytv7dwr0	251	26	.	.	.
cord-010570-ytv7dwr0	252	1	Examples	Examples	NNP
cord-010570-ytv7dwr0	252	2	ofpotential	ofpotential	JJ
cord-010570-ytv7dwr0	252	3	targets	target	NNS
cord-010570-ytv7dwr0	252	4	for	for	IN
cord-010570-ytv7dwr0	252	5	antibody	antibody	NN
cord-010570-ytv7dwr0	252	6	-	-	HYPH
cord-010570-ytv7dwr0	252	7	based	base	VBN
cord-010570-ytv7dwr0	252	8	therapy	therapy	NN
cord-010570-ytv7dwr0	252	9	include	include	VBP
cord-010570-ytv7dwr0	252	10	the	the	DT
cord-010570-ytv7dwr0	252	11	toxins	toxin	NNS
cord-010570-ytv7dwr0	252	12	and	and	CC
cord-010570-ytv7dwr0	252	13	proteases	protease	NNS
cord-010570-ytv7dwr0	252	14	associated	associate	VBN
cord-010570-ytv7dwr0	252	15	with	with	IN
cord-010570-ytv7dwr0	252	16	toxic	toxic	JJ
cord-010570-ytv7dwr0	252	17	shock	shock	NN
cord-010570-ytv7dwr0	252	18	syndromes	syndrome	NNS
cord-010570-ytv7dwr0	252	19	[	[	-LRB-
cord-010570-ytv7dwr0	252	20	161	161	CD
cord-010570-ytv7dwr0	252	21	,	,	,
cord-010570-ytv7dwr0	252	22	162	162	CD
cord-010570-ytv7dwr0	252	23	]	]	-RRB-
cord-010570-ytv7dwr0	252	24	.	.	.
cord-010570-ytv7dwr0	253	1	Combination	combination	NN
cord-010570-ytv7dwr0	253	2	therapy	therapy	NN
cord-010570-ytv7dwr0	253	3	with	with	IN
cord-010570-ytv7dwr0	253	4	antibodies	antibody	NNS
cord-010570-ytv7dwr0	253	5	to	to	IN
cord-010570-ytv7dwr0	253	6	exotoxins	exotoxin	NNS
cord-010570-ytv7dwr0	253	7	could	could	MD
cord-010570-ytv7dwr0	253	8	improve	improve	VB
cord-010570-ytv7dwr0	253	9	outcome	outcome	NN
cord-010570-ytv7dwr0	253	10	,	,	,
cord-010570-ytv7dwr0	253	11	but	but	CC
cord-010570-ytv7dwr0	253	12	cocktails	cocktail	NNS
cord-010570-ytv7dwr0	253	13	of	of	IN
cord-010570-ytv7dwr0	253	14	mAbs	mAbs	NNP
cord-010570-ytv7dwr0	253	15	may	may	MD
cord-010570-ytv7dwr0	253	16	be	be	VB
cord-010570-ytv7dwr0	253	17	necessary	necessary	JJ
cord-010570-ytv7dwr0	253	18	because	because	IN
cord-010570-ytv7dwr0	253	19	of	of	IN
cord-010570-ytv7dwr0	253	20	toxin	toxin	NN
cord-010570-ytv7dwr0	253	21	heterogeneity	heterogeneity	NN
cord-010570-ytv7dwr0	253	22	[	[	-LRB-
cord-010570-ytv7dwr0	253	23	162	162	CD
cord-010570-ytv7dwr0	253	24	]	]	-RRB-
cord-010570-ytv7dwr0	253	25	.	.	.
cord-010570-ytv7dwr0	254	1	Intravenous	intravenous	JJ
cord-010570-ytv7dwr0	254	2	immunoglobulin	immunoglobulin	NN
cord-010570-ytv7dwr0	254	3	administration	administration	NN
cord-010570-ytv7dwr0	254	4	has	have	VBZ
cord-010570-ytv7dwr0	254	5	been	be	VBN
cord-010570-ytv7dwr0	254	6	associated	associate	VBN
cord-010570-ytv7dwr0	254	7	with	with	IN
cord-010570-ytv7dwr0	254	8	dramatic	dramatic	JJ
cord-010570-ytv7dwr0	254	9	clinical	clinical	JJ
cord-010570-ytv7dwr0	254	10	improvement	improvement	NN
cord-010570-ytv7dwr0	254	11	in	in	IN
cord-010570-ytv7dwr0	254	12	a	a	DT
cord-010570-ytv7dwr0	254	13	patient	patient	NN
cord-010570-ytv7dwr0	254	14	with	with	IN
cord-010570-ytv7dwr0	254	15	Streptococcus	streptococcus	NN
cord-010570-ytv7dwr0	254	16	pyogenes	pyogene	NNS
cord-010570-ytv7dwr0	254	17	toxic	toxic	JJ
cord-010570-ytv7dwr0	254	18	shock	shock	NN
cord-010570-ytv7dwr0	254	19	syndrome	syndrome	NN
cord-010570-ytv7dwr0	254	20	[	[	-LRB-
cord-010570-ytv7dwr0	254	21	163	163	CD
cord-010570-ytv7dwr0	254	22	]	]	-RRB-
cord-010570-ytv7dwr0	254	23	.	.	.
cord-010570-ytv7dwr0	255	1	Antivirals	antiviral	NNS
cord-010570-ytv7dwr0	255	2	.	.	.
cord-010570-ytv7dwr0	256	1	Virus	virus	NN
cord-010570-ytv7dwr0	256	2	neutralization	neutralization	NN
cord-010570-ytv7dwr0	256	3	is	be	VBZ
cord-010570-ytv7dwr0	256	4	an	an	DT
cord-010570-ytv7dwr0	256	5	established	established	JJ
cord-010570-ytv7dwr0	256	6	property	property	NN
cord-010570-ytv7dwr0	256	7	of	of	IN
cord-010570-ytv7dwr0	256	8	antibodies	antibody	NNS
cord-010570-ytv7dwr0	256	9	.	.	.
cord-010570-ytv7dwr0	257	1	In	in	IN
cord-010570-ytv7dwr0	257	2	the	the	DT
cord-010570-ytv7dwr0	257	3	preantibiotic	preantibiotic	JJ
cord-010570-ytv7dwr0	257	4	era	era	NN
cord-010570-ytv7dwr0	257	5	,	,	,
cord-010570-ytv7dwr0	257	6	serum	serum	NN
cord-010570-ytv7dwr0	257	7	was	be	VBD
cord-010570-ytv7dwr0	257	8	used	use	VBN
cord-010570-ytv7dwr0	257	9	for	for	IN
cord-010570-ytv7dwr0	257	10	prophylaxis	prophylaxis	NN
cord-010570-ytv7dwr0	257	11	ofmeasles	ofmeasle	NNS
cord-010570-ytv7dwr0	257	12	,	,	,
cord-010570-ytv7dwr0	257	13	chickenpox	chickenpox	NN
cord-010570-ytv7dwr0	257	14	,	,	,
cord-010570-ytv7dwr0	257	15	mumps	mumps	NN
cord-010570-ytv7dwr0	257	16	,	,	,
cord-010570-ytv7dwr0	257	17	and	and	CC
cord-010570-ytv7dwr0	257	18	poliomyelitis	poliomyelitis	NN
cord-010570-ytv7dwr0	257	19	.	.	.
cord-010570-ytv7dwr0	258	1	Recently	recently	RB
cord-010570-ytv7dwr0	258	2	,	,	,
cord-010570-ytv7dwr0	258	3	the	the	DT
cord-010570-ytv7dwr0	258	4	potential	potential	NN
cord-010570-ytv7dwr0	258	5	of	of	IN
cord-010570-ytv7dwr0	258	6	antibody	antibody	NN
cord-010570-ytv7dwr0	258	7	therapy	therapy	NN
cord-010570-ytv7dwr0	258	8	against	against	IN
cord-010570-ytv7dwr0	258	9	many	many	JJ
cord-010570-ytv7dwr0	258	10	viruses	virus	NNS
cord-010570-ytv7dwr0	258	11	,	,	,
cord-010570-ytv7dwr0	258	12	including	include	VBG
cord-010570-ytv7dwr0	258	13	hepatitis	hepatitis	NN
cord-010570-ytv7dwr0	258	14	B	B	NNP
cord-010570-ytv7dwr0	258	15	[	[	-LRB-
cord-010570-ytv7dwr0	258	16	164	164	CD
cord-010570-ytv7dwr0	258	17	]	]	-RRB-
cord-010570-ytv7dwr0	258	18	,	,	,
cord-010570-ytv7dwr0	258	19	HIV	HIV	NNP
cord-010570-ytv7dwr0	258	20	[	[	-LRB-
cord-010570-ytv7dwr0	258	21	165	165	CD
cord-010570-ytv7dwr0	258	22	]	]	-RRB-
cord-010570-ytv7dwr0	258	23	,	,	,
cord-010570-ytv7dwr0	258	24	respiratory	respiratory	JJ
cord-010570-ytv7dwr0	258	25	syncytial	syncytial	JJ
cord-010570-ytv7dwr0	258	26	virus	virus	NN
cord-010570-ytv7dwr0	258	27	[	[	-LRB-
cord-010570-ytv7dwr0	258	28	166	166	CD
cord-010570-ytv7dwr0	258	29	]	]	-RRB-
cord-010570-ytv7dwr0	258	30	,	,	,
cord-010570-ytv7dwr0	258	31	CMV	CMV	NNP
cord-010570-ytv7dwr0	258	32	[	[	-LRB-
cord-010570-ytv7dwr0	258	33	150	150	CD
cord-010570-ytv7dwr0	258	34	]	]	-RRB-
cord-010570-ytv7dwr0	258	35	,	,	,
cord-010570-ytv7dwr0	258	36	and	and	CC
cord-010570-ytv7dwr0	258	37	parvovirus	parvovirus	NN
cord-010570-ytv7dwr0	258	38	[	[	-LRB-
cord-010570-ytv7dwr0	258	39	167	167	CD
cord-010570-ytv7dwr0	258	40	]	]	-RRB-
cord-010570-ytv7dwr0	258	41	,	,	,
cord-010570-ytv7dwr0	258	42	has	have	VBZ
cord-010570-ytv7dwr0	258	43	received	receive	VBN
cord-010570-ytv7dwr0	258	44	considerable	considerable	JJ
cord-010570-ytv7dwr0	258	45	attention	attention	NN
cord-010570-ytv7dwr0	258	46	.	.	.
cord-010570-ytv7dwr0	259	1	Newly	newly	RB
cord-010570-ytv7dwr0	259	2	identified	identify	VBN
cord-010570-ytv7dwr0	259	3	viral	viral	JJ
cord-010570-ytv7dwr0	259	4	illnesses	illness	NNS
cord-010570-ytv7dwr0	259	5	are	be	VBP
cord-010570-ytv7dwr0	259	6	targets	target	NNS
cord-010570-ytv7dwr0	259	7	for	for	IN
cord-010570-ytv7dwr0	259	8	antibody	antibody	NN
cord-010570-ytv7dwr0	259	9	drug	drug	NN
cord-010570-ytv7dwr0	259	10	research	research	NN
cord-010570-ytv7dwr0	259	11	.	.	.
cord-010570-ytv7dwr0	260	1	Combination	combination	NN
cord-010570-ytv7dwr0	260	2	ofantibody	ofantibody	NN
cord-010570-ytv7dwr0	260	3	therapy	therapy	NN
cord-010570-ytv7dwr0	260	4	and	and	CC
cord-010570-ytv7dwr0	260	5	chemotherapy	chemotherapy	NN
cord-010570-ytv7dwr0	260	6	.	.	.
cord-010570-ytv7dwr0	261	1	Antibody	antibody	NN
cord-010570-ytv7dwr0	261	2	-	-	HYPH
cord-010570-ytv7dwr0	261	3	based	base	VBN
cord-010570-ytv7dwr0	261	4	therapies	therapy	NNS
cord-010570-ytv7dwr0	261	5	are	be	VBP
cord-010570-ytv7dwr0	261	6	unlikely	unlikely	JJ
cord-010570-ytv7dwr0	261	7	to	to	TO
cord-010570-ytv7dwr0	261	8	be	be	VB
cord-010570-ytv7dwr0	261	9	used	use	VBN
cord-010570-ytv7dwr0	261	10	alone	alone	RB
cord-010570-ytv7dwr0	261	11	unless	unless	IN
cord-010570-ytv7dwr0	261	12	they	-PRON-	PRP
cord-010570-ytv7dwr0	261	13	are	be	VBP
cord-010570-ytv7dwr0	261	14	the	the	DT
cord-010570-ytv7dwr0	261	15	only	only	JJ
cord-010570-ytv7dwr0	261	16	available	available	JJ
cord-010570-ytv7dwr0	261	17	therapy	therapy	NN
cord-010570-ytv7dwr0	261	18	or	or	CC
cord-010570-ytv7dwr0	261	19	are	be	VBP
cord-010570-ytv7dwr0	261	20	being	be	VBG
cord-010570-ytv7dwr0	261	21	used	use	VBN
cord-010570-ytv7dwr0	261	22	for	for	IN
cord-010570-ytv7dwr0	261	23	prophylaxis	prophylaxis	NN
cord-010570-ytv7dwr0	261	24	of	of	IN
cord-010570-ytv7dwr0	261	25	infection	infection	NN
cord-010570-ytv7dwr0	261	26	.	.	.
cord-010570-ytv7dwr0	262	1	Combinations	combination	NNS
cord-010570-ytv7dwr0	262	2	of	of	IN
cord-010570-ytv7dwr0	262	3	antibody	antibody	NN
cord-010570-ytv7dwr0	262	4	therapy	therapy	NN
cord-010570-ytv7dwr0	262	5	and	and	CC
cord-010570-ytv7dwr0	262	6	chemotherapy	chemotherapy	NN
cord-010570-ytv7dwr0	262	7	offer	offer	VBP
cord-010570-ytv7dwr0	262	8	theoretical	theoretical	JJ
cord-010570-ytv7dwr0	262	9	advantages	advantage	NNS
cord-010570-ytv7dwr0	262	10	.	.	.
cord-010570-ytv7dwr0	263	1	Antibodies	antibody	NNS
cord-010570-ytv7dwr0	263	2	promote	promote	VBP
cord-010570-ytv7dwr0	263	3	microbial	microbial	JJ
cord-010570-ytv7dwr0	263	4	killing	killing	NN
cord-010570-ytv7dwr0	263	5	directly	directly	RB
cord-010570-ytv7dwr0	263	6	by	by	IN
cord-010570-ytv7dwr0	263	7	a	a	DT
cord-010570-ytv7dwr0	263	8	complement	complement	NN
cord-010570-ytv7dwr0	263	9	-	-	HYPH
cord-010570-ytv7dwr0	263	10	mediated	mediate	VBN
cord-010570-ytv7dwr0	263	11	lytic	lytic	JJ
cord-010570-ytv7dwr0	263	12	process	process	NN
cord-010570-ytv7dwr0	263	13	or	or	CC
cord-010570-ytv7dwr0	263	14	indirectly	indirectly	RB
cord-010570-ytv7dwr0	263	15	by	by	IN
cord-010570-ytv7dwr0	263	16	enhancing	enhance	VBG
cord-010570-ytv7dwr0	263	17	nonspecific	nonspecific	JJ
cord-010570-ytv7dwr0	263	18	immune	immune	JJ
cord-010570-ytv7dwr0	263	19	mechanisms	mechanism	NNS
cord-010570-ytv7dwr0	263	20	.	.	.
cord-010570-ytv7dwr0	264	1	Table	table	NN
cord-010570-ytv7dwr0	264	2	3	3	CD
cord-010570-ytv7dwr0	264	3	lists	list	VBZ
cord-010570-ytv7dwr0	264	4	examples	example	NNS
cord-010570-ytv7dwr0	264	5	of	of	IN
cord-010570-ytv7dwr0	264	6	bacterial	bacterial	JJ
cord-010570-ytv7dwr0	264	7	,	,	,
cord-010570-ytv7dwr0	264	8	fungal	fungal	JJ
cord-010570-ytv7dwr0	264	9	,	,	,
cord-010570-ytv7dwr0	264	10	and	and	CC
cord-010570-ytv7dwr0	264	11	viral	viral	JJ
cord-010570-ytv7dwr0	264	12	pathogens	pathogen	NNS
cord-010570-ytv7dwr0	264	13	for	for	IN
cord-010570-ytv7dwr0	264	14	which	which	WDT
cord-010570-ytv7dwr0	264	15	combination	combination	NN
cord-010570-ytv7dwr0	264	16	therapy	therapy	NN
cord-010570-ytv7dwr0	264	17	has	have	VBZ
cord-010570-ytv7dwr0	264	18	shown	show	VBN
cord-010570-ytv7dwr0	264	19	promise	promise	NN
cord-010570-ytv7dwr0	264	20	.	.	.
cord-010570-ytv7dwr0	265	1	Combination	combination	NN
cord-010570-ytv7dwr0	265	2	therapy	therapy	NN
cord-010570-ytv7dwr0	265	3	could	could	MD
cord-010570-ytv7dwr0	265	4	reduce	reduce	VB
cord-010570-ytv7dwr0	265	5	the	the	DT
cord-010570-ytv7dwr0	265	6	amount	amount	NN
cord-010570-ytv7dwr0	265	7	of	of	IN
cord-010570-ytv7dwr0	265	8	either	either	DT
cord-010570-ytv7dwr0	265	9	agent	agent	NN
cord-010570-ytv7dwr0	265	10	required	require	VBN
cord-010570-ytv7dwr0	265	11	to	to	IN
cord-010570-ytv7dwr0	265	12	Table	Table	NNP
cord-010570-ytv7dwr0	265	13	3	3	CD
cord-010570-ytv7dwr0	265	14	.	.	.
cord-010570-ytv7dwr0	266	1	Pathogens	pathogen	NNS
cord-010570-ytv7dwr0	266	2	for	for	IN
cord-010570-ytv7dwr0	266	3	which	which	WDT
cord-010570-ytv7dwr0	266	4	the	the	DT
cord-010570-ytv7dwr0	266	5	combination	combination	NN
cord-010570-ytv7dwr0	266	6	of	of	IN
cord-010570-ytv7dwr0	266	7	chemotherapy	chemotherapy	NN
cord-010570-ytv7dwr0	266	8	and	and	CC
cord-010570-ytv7dwr0	266	9	antibody	antibody	NN
cord-010570-ytv7dwr0	266	10	based	base	VBN
cord-010570-ytv7dwr0	266	11	therapy	therapy	NN
cord-010570-ytv7dwr0	266	12	has	have	VBZ
cord-010570-ytv7dwr0	266	13	shown	show	VBN
cord-010570-ytv7dwr0	266	14	some	some	DT
cord-010570-ytv7dwr0	266	15	promise	promise	NN
cord-010570-ytv7dwr0	266	16	.	.	.
cord-010570-ytv7dwr0	267	1	Pathogen	Pathogen	NNP
cord-010570-ytv7dwr0	267	2	Chemotherapy	Chemotherapy	NNP
cord-010570-ytv7dwr0	267	3	Antibody	Antibody	NNP
cord-010570-ytv7dwr0	267	4	[	[	-LRB-
cord-010570-ytv7dwr0	267	5	57	57	CD
cord-010570-ytv7dwr0	267	6	,	,	,
cord-010570-ytv7dwr0	267	7	168	168	CD
cord-010570-ytv7dwr0	267	8	]	]	-RRB-
cord-010570-ytv7dwr0	267	9	Neisseria	Neisseria	NNP
cord-010570-ytv7dwr0	267	10	meningitidis	meningitidis	NN
cord-010570-ytv7dwr0	267	11	Sulfanilamide	Sulfanilamide	NNP
cord-010570-ytv7dwr0	267	12	Horse	Horse	NNP
cord-010570-ytv7dwr0	267	13	immune	immune	JJ
cord-010570-ytv7dwr0	267	14	sera	sera	NNP
cord-010570-ytv7dwr0	267	15	[	[	-LRB-
cord-010570-ytv7dwr0	267	16	55	55	CD
cord-010570-ytv7dwr0	267	17	]	]	-RRB-
cord-010570-ytv7dwr0	267	18	Streptococcus	streptococcus	NN
cord-010570-ytv7dwr0	267	19	pneumoniae	pneumoniae	NN
cord-010570-ytv7dwr0	267	20	Rabbit	Rabbit	NNP
cord-010570-ytv7dwr0	267	21	immune	immune	JJ
cord-010570-ytv7dwr0	267	22	sera	sera	NNP
cord-010570-ytv7dwr0	268	1	[	[	-LRB-
cord-010570-ytv7dwr0	268	2	8	8	CD
cord-010570-ytv7dwr0	268	3	,	,	,
cord-010570-ytv7dwr0	268	4	9	9	CD
cord-010570-ytv7dwr0	268	5	]	]	-RRB-
cord-010570-ytv7dwr0	269	1	Haemophilus	Haemophilus	NNP
cord-010570-ytv7dwr0	269	2	infiuenzae	infiuenzae	NN
cord-010570-ytv7dwr0	269	3	Sulfonamide	Sulfonamide	NNP
cord-010570-ytv7dwr0	269	4	Rabbit	Rabbit	NNP
cord-010570-ytv7dwr0	269	5	,	,	,
cord-010570-ytv7dwr0	269	6	horse	horse	NN
cord-010570-ytv7dwr0	269	7	immune	immune	NN
cord-010570-ytv7dwr0	269	8	sera	sera	NNP
cord-010570-ytv7dwr0	269	9	[	[	-LRB-
cord-010570-ytv7dwr0	269	10	169	169	CD
cord-010570-ytv7dwr0	269	11	]	]	-RRB-
cord-010570-ytv7dwr0	269	12	Staphylococcus	Staphylococcus	NNP
cord-010570-ytv7dwr0	269	13	aureus	aureus	NN
cord-010570-ytv7dwr0	269	14	 	 	_SP
cord-010570-ytv7dwr0	269	15	Sparftoxacin	Sparftoxacin	NNP
cord-010570-ytv7dwr0	269	16	Human	Human	NNP
cord-010570-ytv7dwr0	269	17	IgG1	IgG1	NNP
cord-010570-ytv7dwr0	269	18	mAb	mab	NN
cord-010570-ytv7dwr0	269	19	[	[	-LRB-
cord-010570-ytv7dwr0	269	20	172	172	CD
cord-010570-ytv7dwr0	269	21	]	]	-RRB-
cord-010570-ytv7dwr0	269	22	P.	P.	NNP
cord-010570-ytv7dwr0	269	23	aeruginosa	aeruginosa	NNP
cord-010570-ytv7dwr0	269	24	Human	Human	NNP
cord-010570-ytv7dwr0	269	25	IgM	IgM	NNP
cord-010570-ytv7dwr0	270	1	mAb	mAb	NNS
cord-010570-ytv7dwr0	270	2	[	[	-LRB-
cord-010570-ytv7dwr0	270	3	173	173	CD
cord-010570-ytv7dwr0	270	4	]	]	-RRB-
cord-010570-ytv7dwr0	270	5	P.	P.	NNP
cord-010570-ytv7dwr0	270	6	aeruginosa	aeruginosa	NNP
cord-010570-ytv7dwr0	270	7	Murine	Murine	NNP
cord-010570-ytv7dwr0	270	8	E5	E5	NNP
cord-010570-ytv7dwr0	270	9	LPS	LPS	NNP
cord-010570-ytv7dwr0	270	10	antibodies	antibody	NNS
cord-010570-ytv7dwr0	270	11	[	[	-LRB-
cord-010570-ytv7dwr0	270	12	170	170	CD
cord-010570-ytv7dwr0	270	13	]	]	-RRB-
cord-010570-ytv7dwr0	271	1	P.	P.	NNP
cord-010570-ytv7dwr0	271	2	aeruginosa	aeruginosa	NNP
cord-010570-ytv7dwr0	271	3	Human	Human	NNP
cord-010570-ytv7dwr0	271	4	gamma	gamma	NN
cord-010570-ytv7dwr0	271	5	globulin	globulin	NN
cord-010570-ytv7dwr0	271	6	[	[	-LRB-
cord-010570-ytv7dwr0	271	7	172	172	CD
cord-010570-ytv7dwr0	271	8	]	]	-RRB-
cord-010570-ytv7dwr0	271	9	Escherichia	escherichia	NN
cord-010570-ytv7dwr0	271	10	coli	coli	VBZ
cord-010570-ytv7dwr0	271	11	Murine	Murine	NNP
cord-010570-ytv7dwr0	271	12	E5	E5	NNP
cord-010570-ytv7dwr0	271	13	LPS	LPS	NNP
cord-010570-ytv7dwr0	271	14	antibodies	antibody	NNS
cord-010570-ytv7dwr0	271	15	[	[	-LRB-
cord-010570-ytv7dwr0	271	16	174	174	CD
cord-010570-ytv7dwr0	271	17	]	]	-RRB-
cord-010570-ytv7dwr0	271	18	Shistosoma	Shistosoma	NNP
cord-010570-ytv7dwr0	271	19	mansoni	mansoni	NN
cord-010570-ytv7dwr0	271	20	Praziquantel	Praziquantel	NNP
cord-010570-ytv7dwr0	271	21	Rabbit	Rabbit	NNP
cord-010570-ytv7dwr0	271	22	immune	immune	NN
cord-010570-ytv7dwr0	271	23	sera	sera	NNP
cord-010570-ytv7dwr0	271	24	[	[	-LRB-
cord-010570-ytv7dwr0	271	25	175	175	CD
cord-010570-ytv7dwr0	271	26	]	]	-RRB-
cord-010570-ytv7dwr0	271	27	Candida	Candida	NNP
cord-010570-ytv7dwr0	271	28	albicans	albican	NNS
cord-010570-ytv7dwr0	271	29	Amphotericin	Amphotericin	NNP
cord-010570-ytv7dwr0	271	30	B	B	NNP
cord-010570-ytv7dwr0	271	31	Human	Human	NNP
cord-010570-ytv7dwr0	271	32	gamma	gamma	NN
cord-010570-ytv7dwr0	271	33	globulin	globulin	NN
cord-010570-ytv7dwr0	271	34	[	[	-LRB-
cord-010570-ytv7dwr0	271	35	137	137	CD
cord-010570-ytv7dwr0	271	36	]	]	-RRB-
cord-010570-ytv7dwr0	272	1	Cryptococcus	Cryptococcus	NNP
cord-010570-ytv7dwr0	272	2	neoformans	neoforman	NNS
cord-010570-ytv7dwr0	273	1	Amphotericin	Amphotericin	NNP
cord-010570-ytv7dwr0	273	2	B	B	NNP
cord-010570-ytv7dwr0	273	3	Rabbit	Rabbit	NNP
cord-010570-ytv7dwr0	273	4	immune	immune	NN
cord-010570-ytv7dwr0	273	5	sera	sera	NNP
cord-010570-ytv7dwr0	273	6	[	[	-LRB-
cord-010570-ytv7dwr0	273	7	138	138	CD
cord-010570-ytv7dwr0	273	8	,	,	,
cord-010570-ytv7dwr0	273	9	139	139	CD
cord-010570-ytv7dwr0	273	10	]	]	-RRB-
cord-010570-ytv7dwr0	273	11	C.	C.	NNP
cord-010570-ytv7dwr0	273	12	neoformans	neoformans	NNP
cord-010570-ytv7dwr0	274	1	Murine	Murine	NNP
cord-010570-ytv7dwr0	274	2	IgG1	IgG1	NNP
cord-010570-ytv7dwr0	275	1	mAb	mAb	NNS
cord-010570-ytv7dwr0	275	2	[	[	-LRB-
cord-010570-ytv7dwr0	275	3	176	176	CD
cord-010570-ytv7dwr0	275	4	]	]	-RRB-
cord-010570-ytv7dwr0	275	5	C.	C.	NNP
cord-010570-ytv7dwr0	275	6	neoformans	neoforman	VBZ
cord-010570-ytv7dwr0	275	7	Murine	Murine	NNP
cord-010570-ytv7dwr0	276	1	IgG1	IgG1	NNP
cord-010570-ytv7dwr0	276	2	mAb	mab	IN
cord-010570-ytv7dwr0	276	3	[	[	-LRB-
cord-010570-ytv7dwr0	276	4	177	177	CD
cord-010570-ytv7dwr0	276	5	]	]	-RRB-
cord-010570-ytv7dwr0	276	6	Lassa	Lassa	NNP
cord-010570-ytv7dwr0	276	7	virus	virus	NN
cord-010570-ytv7dwr0	276	8	Ribavirin	Ribavirin	NNP
cord-010570-ytv7dwr0	276	9	Monkey	Monkey	NNP
cord-010570-ytv7dwr0	276	10	immune	immune	NN
cord-010570-ytv7dwr0	276	11	sera	sera	NNP
cord-010570-ytv7dwr0	276	12	[	[	-LRB-
cord-010570-ytv7dwr0	276	13	72	72	CD
cord-010570-ytv7dwr0	276	14	,	,	,
cord-010570-ytv7dwr0	276	15	178	178	CD
cord-010570-ytv7dwr0	276	16	]	]	-RRB-
cord-010570-ytv7dwr0	277	1	Cytomegalovirus	Cytomegalovirus	NNP
cord-010570-ytv7dwr0	277	2	Ganciclovir	Ganciclovir	NNP
cord-010570-ytv7dwr0	277	3	Murine	Murine	NNP
cord-010570-ytv7dwr0	277	4	immune	immune	NN
cord-010570-ytv7dwr0	277	5	sera	sera	NNP
cord-010570-ytv7dwr0	278	1	[	[	-LRB-
cord-010570-ytv7dwr0	278	2	179	179	CD
cord-010570-ytv7dwr0	278	3	]	]	-RRB-
cord-010570-ytv7dwr0	278	4	Herpes	Herpes	NNP
cord-010570-ytv7dwr0	278	5	simplex	simplex	NN
cord-010570-ytv7dwr0	278	6	virus	virus	NN
cord-010570-ytv7dwr0	278	7	Adenine	adenine	NN
cord-010570-ytv7dwr0	278	8	arabinoside	arabinoside	NN
cord-010570-ytv7dwr0	278	9	Rabbit	Rabbit	NNP
cord-010570-ytv7dwr0	278	10	and	and	CC
cord-010570-ytv7dwr0	278	11	human	human	JJ
cord-010570-ytv7dwr0	278	12	sera	sera	NNP
cord-010570-ytv7dwr0	278	13	[	[	-LRB-
cord-010570-ytv7dwr0	278	14	180	180	CD
cord-010570-ytv7dwr0	278	15	]	]	-RRB-
cord-010570-ytv7dwr0	278	16	Herpes	Herpes	NNP
cord-010570-ytv7dwr0	278	17	simplex	simplex	NN
cord-010570-ytv7dwr0	278	18	virus	virus	NN
cord-010570-ytv7dwr0	278	19	Acycloguanosine	Acycloguanosine	NNP
cord-010570-ytv7dwr0	278	20	Human	Human	NNP
cord-010570-ytv7dwr0	278	21	immune	immune	JJ
cord-010570-ytv7dwr0	278	22	globulin	globulin	NN
cord-010570-ytv7dwr0	278	23	NOTE	note	NN
cord-010570-ytv7dwr0	278	24	.	.	.
cord-010570-ytv7dwr0	279	1	This	this	DT
cord-010570-ytv7dwr0	279	2	is	be	VBZ
cord-010570-ytv7dwr0	279	3	not	not	RB
cord-010570-ytv7dwr0	279	4	a	a	DT
cord-010570-ytv7dwr0	279	5	complete	complete	JJ
cord-010570-ytv7dwr0	279	6	list	list	NN
cord-010570-ytv7dwr0	279	7	.	.	.
cord-010570-ytv7dwr0	280	1	achieve	achieve	VB
cord-010570-ytv7dwr0	280	2	a	a	DT
cord-010570-ytv7dwr0	280	3	therapeutic	therapeutic	JJ
cord-010570-ytv7dwr0	280	4	effect	effect	NN
cord-010570-ytv7dwr0	280	5	.	.	.
cord-010570-ytv7dwr0	281	1	For	for	IN
cord-010570-ytv7dwr0	281	2	example	example	NN
cord-010570-ytv7dwr0	281	3	,	,	,
cord-010570-ytv7dwr0	281	4	some	some	DT
cord-010570-ytv7dwr0	281	5	antibiotics	antibiotic	NNS
cord-010570-ytv7dwr0	281	6	are	be	VBP
cord-010570-ytv7dwr0	281	7	quite	quite	RB
cord-010570-ytv7dwr0	281	8	toxic	toxic	JJ
cord-010570-ytv7dwr0	281	9	,	,	,
cord-010570-ytv7dwr0	281	10	and	and	CC
cord-010570-ytv7dwr0	281	11	the	the	DT
cord-010570-ytv7dwr0	281	12	ability	ability	NN
cord-010570-ytv7dwr0	281	13	to	to	TO
cord-010570-ytv7dwr0	281	14	reduce	reduce	VB
cord-010570-ytv7dwr0	281	15	doses	dose	NNS
cord-010570-ytv7dwr0	281	16	could	could	MD
cord-010570-ytv7dwr0	281	17	lessen	lessen	VB
cord-010570-ytv7dwr0	281	18	side	side	NN
cord-010570-ytv7dwr0	281	19	effects	effect	NNS
cord-010570-ytv7dwr0	281	20	.	.	.
cord-010570-ytv7dwr0	282	1	In	in	IN
cord-010570-ytv7dwr0	282	2	a	a	DT
cord-010570-ytv7dwr0	282	3	similar	similar	JJ
cord-010570-ytv7dwr0	282	4	vein	vein	NN
cord-010570-ytv7dwr0	282	5	,	,	,
cord-010570-ytv7dwr0	282	6	the	the	DT
cord-010570-ytv7dwr0	282	7	addition	addition	NN
cord-010570-ytv7dwr0	282	8	of	of	IN
cord-010570-ytv7dwr0	282	9	chemotherapy	chemotherapy	NN
cord-010570-ytv7dwr0	282	10	to	to	IN
cord-010570-ytv7dwr0	282	11	antibody	antibody	NN
cord-010570-ytv7dwr0	282	12	therapy	therapy	NN
cord-010570-ytv7dwr0	282	13	could	could	MD
cord-010570-ytv7dwr0	282	14	reduce	reduce	VB
cord-010570-ytv7dwr0	282	15	the	the	DT
cord-010570-ytv7dwr0	282	16	amount	amount	NN
cord-010570-ytv7dwr0	282	17	of	of	IN
cord-010570-ytv7dwr0	282	18	antibody	antibody	NN
cord-010570-ytv7dwr0	282	19	necessary	necessary	JJ
cord-010570-ytv7dwr0	282	20	to	to	TO
cord-010570-ytv7dwr0	282	21	achieve	achieve	VB
cord-010570-ytv7dwr0	282	22	a	a	DT
cord-010570-ytv7dwr0	282	23	therapeutic	therapeutic	JJ
cord-010570-ytv7dwr0	282	24	effect	effect	NN
cord-010570-ytv7dwr0	282	25	,	,	,
cord-010570-ytv7dwr0	282	26	which	which	WDT
cord-010570-ytv7dwr0	282	27	would	would	MD
cord-010570-ytv7dwr0	282	28	lessen	lessen	VB
cord-010570-ytv7dwr0	282	29	the	the	DT
cord-010570-ytv7dwr0	282	30	cost	cost	NN
cord-010570-ytv7dwr0	282	31	of	of	IN
cord-010570-ytv7dwr0	282	32	therapy	therapy	NN
cord-010570-ytv7dwr0	282	33	.	.	.
cord-010570-ytv7dwr0	283	1	The	the	DT
cord-010570-ytv7dwr0	283	2	availability	availability	NN
cord-010570-ytv7dwr0	283	3	of	of	IN
cord-010570-ytv7dwr0	283	4	broad	broad	JJ
cord-010570-ytv7dwr0	283	5	-	-	HYPH
cord-010570-ytv7dwr0	283	6	spectrum	spectrum	NN
cord-010570-ytv7dwr0	283	7	antibiotics	antibiotic	NNS
cord-010570-ytv7dwr0	283	8	has	have	VBZ
cord-010570-ytv7dwr0	283	9	diminished	diminish	VBN
cord-010570-ytv7dwr0	283	10	the	the	DT
cord-010570-ytv7dwr0	283	11	need	need	NN
cord-010570-ytv7dwr0	283	12	for	for	IN
cord-010570-ytv7dwr0	283	13	making	make	VBG
cord-010570-ytv7dwr0	283	14	exact	exact	JJ
cord-010570-ytv7dwr0	283	15	microbiological	microbiological	JJ
cord-010570-ytv7dwr0	283	16	diagnoses	diagnosis	NNS
cord-010570-ytv7dwr0	283	17	.	.	.
cord-010570-ytv7dwr0	284	1	For	for	IN
cord-010570-ytv7dwr0	284	2	example	example	NN
cord-010570-ytv7dwr0	284	3	,	,	,
cord-010570-ytv7dwr0	284	4	gram	gram	NN
cord-010570-ytv7dwr0	284	5	-	-	HYPH
cord-010570-ytv7dwr0	284	6	negative	negative	JJ
cord-010570-ytv7dwr0	284	7	sepsis	sepsis	NN
cord-010570-ytv7dwr0	284	8	or	or	CC
cord-010570-ytv7dwr0	284	9	presumed	presume	VBN
cord-010570-ytv7dwr0	284	10	fungal	fungal	JJ
cord-010570-ytv7dwr0	284	11	infections	infection	NNS
cord-010570-ytv7dwr0	284	12	can	can	MD
cord-010570-ytv7dwr0	284	13	be	be	VB
cord-010570-ytv7dwr0	284	14	treated	treat	VBN
cord-010570-ytv7dwr0	284	15	with	with	IN
cord-010570-ytv7dwr0	284	16	empirical	empirical	JJ
cord-010570-ytv7dwr0	284	17	therapy	therapy	NN
cord-010570-ytv7dwr0	284	18	without	without	IN
cord-010570-ytv7dwr0	284	19	identifying	identify	VBG
cord-010570-ytv7dwr0	284	20	the	the	DT
cord-010570-ytv7dwr0	284	21	pathogen	pathogen	NN
cord-010570-ytv7dwr0	284	22	.	.	.
cord-010570-ytv7dwr0	285	1	This	this	DT
cord-010570-ytv7dwr0	285	2	situation	situation	NN
cord-010570-ytv7dwr0	285	3	is	be	VBZ
cord-010570-ytv7dwr0	285	4	in	in	IN
cord-010570-ytv7dwr0	285	5	contrast	contrast	NN
cord-010570-ytv7dwr0	285	6	to	to	IN
cord-010570-ytv7dwr0	285	7	the	the	DT
cord-010570-ytv7dwr0	285	8	practice	practice	NN
cord-010570-ytv7dwr0	285	9	of	of	IN
cord-010570-ytv7dwr0	285	10	infectious	infectious	JJ
cord-010570-ytv7dwr0	285	11	diseases	disease	NNS
cord-010570-ytv7dwr0	285	12	in	in	IN
cord-010570-ytv7dwr0	285	13	the	the	DT
cord-010570-ytv7dwr0	285	14	1930s	1930	NNS
cord-010570-ytv7dwr0	285	15	when	when	WRB
cord-010570-ytv7dwr0	285	16	identification	identification	NN
cord-010570-ytv7dwr0	285	17	of	of	IN
cord-010570-ytv7dwr0	285	18	the	the	DT
cord-010570-ytv7dwr0	285	19	pathogen	pathogen	NN
cord-010570-ytv7dwr0	285	20	(	(	-LRB-
cord-010570-ytv7dwr0	285	21	and	and	CC
cord-010570-ytv7dwr0	285	22	its	-PRON-	PRP$
cord-010570-ytv7dwr0	285	23	serotype	serotype	NN
cord-010570-ytv7dwr0	285	24	)	)	-RRB-
cord-010570-ytv7dwr0	285	25	was	be	VBD
cord-010570-ytv7dwr0	285	26	necessary	necessary	JJ
cord-010570-ytv7dwr0	285	27	for	for	IN
cord-010570-ytv7dwr0	285	28	choosing	choose	VBG
cord-010570-ytv7dwr0	285	29	the	the	DT
cord-010570-ytv7dwr0	285	30	correct	correct	JJ
cord-010570-ytv7dwr0	285	31	antiserum	antiserum	NN
cord-010570-ytv7dwr0	285	32	.	.	.
cord-010570-ytv7dwr0	286	1	For	for	IN
cord-010570-ytv7dwr0	286	2	antigenically	antigenically	RB
cord-010570-ytv7dwr0	286	3	diverse	diverse	JJ
cord-010570-ytv7dwr0	286	4	pathogens	pathogen	NNS
cord-010570-ytv7dwr0	286	5	such	such	JJ
cord-010570-ytv7dwr0	286	6	as	as	IN
cord-010570-ytv7dwr0	286	7	S.	S.	NNP
cord-010570-ytv7dwr0	286	8	pneumoniae	pneumoniae	NN
cord-010570-ytv7dwr0	286	9	,	,	,
cord-010570-ytv7dwr0	286	10	rapid	rapid	JJ
cord-010570-ytv7dwr0	286	11	protocols	protocol	NNS
cord-010570-ytv7dwr0	286	12	were	be	VBD
cord-010570-ytv7dwr0	286	13	developed	develop	VBN
cord-010570-ytv7dwr0	286	14	for	for	IN
cord-010570-ytv7dwr0	286	15	typing	type	VBG
cord-010570-ytv7dwr0	286	16	strains	strain	NNS
cord-010570-ytv7dwr0	286	17	.	.	.
cord-010570-ytv7dwr0	287	1	The	the	DT
cord-010570-ytv7dwr0	287	2	present	present	JJ
cord-010570-ytv7dwr0	287	3	practice	practice	NN
cord-010570-ytv7dwr0	287	4	of	of	IN
cord-010570-ytv7dwr0	287	5	infectious	infectious	JJ
cord-010570-ytv7dwr0	287	6	diseases	disease	NNS
cord-010570-ytv7dwr0	287	7	is	be	VBZ
cord-010570-ytv7dwr0	287	8	not	not	RB
cord-010570-ytv7dwr0	287	9	unlike	unlike	IN
cord-010570-ytv7dwr0	287	10	a	a	DT
cord-010570-ytv7dwr0	287	11	gambling	gambling	NN
cord-010570-ytv7dwr0	287	12	strategy	strategy	NN
cord-010570-ytv7dwr0	287	13	where	where	WRB
cord-010570-ytv7dwr0	287	14	the	the	DT
cord-010570-ytv7dwr0	287	15	probability	probability	NN
cord-010570-ytv7dwr0	287	16	of	of	IN
cord-010570-ytv7dwr0	287	17	infection	infection	NN
cord-010570-ytv7dwr0	287	18	by	by	IN
cord-010570-ytv7dwr0	287	19	a	a	DT
cord-010570-ytv7dwr0	287	20	given	give	VBN
cord-010570-ytv7dwr0	287	21	microbe	microbe	NN
cord-010570-ytv7dwr0	287	22	is	be	VBZ
cord-010570-ytv7dwr0	287	23	matched	match	VBN
cord-010570-ytv7dwr0	287	24	to	to	IN
cord-010570-ytv7dwr0	287	25	the	the	DT
cord-010570-ytv7dwr0	287	26	likelihood	likelihood	NN
cord-010570-ytv7dwr0	287	27	of	of	IN
cord-010570-ytv7dwr0	287	28	activity	activity	NN
cord-010570-ytv7dwr0	287	29	by	by	IN
cord-010570-ytv7dwr0	287	30	the	the	DT
cord-010570-ytv7dwr0	287	31	available	available	JJ
cord-010570-ytv7dwr0	287	32	antibiotics	antibiotic	NNS
cord-010570-ytv7dwr0	287	33	.	.	.
cord-010570-ytv7dwr0	288	1	This	this	DT
cord-010570-ytv7dwr0	288	2	has	have	VBZ
cord-010570-ytv7dwr0	288	3	resulted	result	VBN
cord-010570-ytv7dwr0	288	4	in	in	IN
cord-010570-ytv7dwr0	288	5	great	great	JJ
cord-010570-ytv7dwr0	288	6	emphasis	emphasis	NN
cord-010570-ytv7dwr0	288	7	on	on	IN
cord-010570-ytv7dwr0	288	8	broad	broad	JJ
cord-010570-ytv7dwr0	288	9	-	-	HYPH
cord-010570-ytv7dwr0	288	10	spectrum	spectrum	NN
cord-010570-ytv7dwr0	288	11	antibiotic	antibiotic	NN
cord-010570-ytv7dwr0	288	12	"	"	''
cord-010570-ytv7dwr0	288	13	coverage	coverage	NN
cord-010570-ytv7dwr0	288	14	"	"	''
cord-010570-ytv7dwr0	288	15	and	and	CC
cord-010570-ytv7dwr0	288	16	less	less	JJR
cord-010570-ytv7dwr0	288	17	emphasis	emphasis	NN
cord-010570-ytv7dwr0	288	18	on	on	IN
cord-010570-ytv7dwr0	288	19	making	make	VBG
cord-010570-ytv7dwr0	288	20	an	an	DT
cord-010570-ytv7dwr0	288	21	exact	exact	JJ
cord-010570-ytv7dwr0	288	22	microbiological	microbiological	JJ
cord-010570-ytv7dwr0	288	23	diagnosis	diagnosis	NN
cord-010570-ytv7dwr0	288	24	.	.	.
cord-010570-ytv7dwr0	289	1	Although	although	IN
cord-010570-ytv7dwr0	289	2	the	the	DT
cord-010570-ytv7dwr0	289	3	relative	relative	JJ
cord-010570-ytv7dwr0	289	4	merits	merit	NNS
cord-010570-ytv7dwr0	289	5	of	of	IN
cord-010570-ytv7dwr0	289	6	this	this	DT
cord-010570-ytv7dwr0	289	7	practice	practice	NN
cord-010570-ytv7dwr0	289	8	are	be	VBP
cord-010570-ytv7dwr0	289	9	beyond	beyond	IN
cord-010570-ytv7dwr0	289	10	the	the	DT
cord-010570-ytv7dwr0	289	11	scope	scope	NN
cord-010570-ytv7dwr0	289	12	of	of	IN
cord-010570-ytv7dwr0	289	13	this	this	DT
cord-010570-ytv7dwr0	289	14	article	article	NN
cord-010570-ytv7dwr0	289	15	,	,	,
cord-010570-ytv7dwr0	289	16	widespread	widespread	JJ
cord-010570-ytv7dwr0	289	17	antimicrobial	antimicrobial	JJ
cord-010570-ytv7dwr0	289	18	resistance	resistance	NN
cord-010570-ytv7dwr0	289	19	is	be	VBZ
cord-010570-ytv7dwr0	289	20	decreasing	decrease	VBG
cord-010570-ytv7dwr0	289	21	the	the	DT
cord-010570-ytv7dwr0	289	22	effectiveness	effectiveness	NN
cord-010570-ytv7dwr0	289	23	of	of	IN
cord-010570-ytv7dwr0	289	24	existing	exist	VBG
cord-010570-ytv7dwr0	289	25	antibiotics	antibiotic	NNS
cord-010570-ytv7dwr0	289	26	,	,	,
cord-010570-ytv7dwr0	289	27	and	and	CC
cord-010570-ytv7dwr0	289	28	increased	increased	JJ
cord-010570-ytv7dwr0	289	29	caution	caution	NN
cord-010570-ytv7dwr0	289	30	is	be	VBZ
cord-010570-ytv7dwr0	289	31	warranted	warrant	VBN
cord-010570-ytv7dwr0	289	32	when	when	WRB
cord-010570-ytv7dwr0	289	33	designing	design	VBG
cord-010570-ytv7dwr0	289	34	broad	broad	JJ
cord-010570-ytv7dwr0	289	35	-	-	HYPH
cord-010570-ytv7dwr0	289	36	spectrum	spectrum	NN
cord-010570-ytv7dwr0	289	37	combinations	combination	NNS
cord-010570-ytv7dwr0	289	38	.	.	.
cord-010570-ytv7dwr0	290	1	A	a	DT
cord-010570-ytv7dwr0	290	2	return	return	NN
cord-010570-ytv7dwr0	290	3	to	to	IN
cord-010570-ytv7dwr0	290	4	antibody	antibody	NN
cord-010570-ytv7dwr0	290	5	therapy	therapy	NN
cord-010570-ytv7dwr0	290	6	would	would	MD
cord-010570-ytv7dwr0	290	7	force	force	VB
cord-010570-ytv7dwr0	290	8	greater	great	JJR
cord-010570-ytv7dwr0	290	9	emphasis	emphasis	NN
cord-010570-ytv7dwr0	290	10	on	on	IN
cord-010570-ytv7dwr0	290	11	precise	precise	JJ
cord-010570-ytv7dwr0	290	12	microbiological	microbiological	JJ
cord-010570-ytv7dwr0	290	13	diagnosis	diagnosis	NN
cord-010570-ytv7dwr0	290	14	and	and	CC
cord-010570-ytv7dwr0	290	15	would	would	MD
cord-010570-ytv7dwr0	290	16	foster	foster	VB
cord-010570-ytv7dwr0	290	17	the	the	DT
cord-010570-ytv7dwr0	290	18	development	development	NN
cord-010570-ytv7dwr0	290	19	of	of	IN
cord-010570-ytv7dwr0	290	20	more	more	RBR
cord-010570-ytv7dwr0	290	21	accurate	accurate	JJ
cord-010570-ytv7dwr0	290	22	and	and	CC
cord-010570-ytv7dwr0	290	23	more	more	RBR
cord-010570-ytv7dwr0	290	24	rapid	rapid	JJ
cord-010570-ytv7dwr0	290	25	diagnostic	diagnostic	JJ
cord-010570-ytv7dwr0	290	26	strategies	strategy	NNS
cord-010570-ytv7dwr0	290	27	.	.	.
cord-010570-ytv7dwr0	291	1	The	the	DT
cord-010570-ytv7dwr0	291	2	use	use	NN
cord-010570-ytv7dwr0	291	3	of	of	IN
cord-010570-ytv7dwr0	291	4	antibody	antibody	NN
cord-010570-ytv7dwr0	291	5	-	-	HYPH
cord-010570-ytv7dwr0	291	6	based	base	VBN
cord-010570-ytv7dwr0	291	7	therapies	therapy	NNS
cord-010570-ytv7dwr0	291	8	may	may	MD
cord-010570-ytv7dwr0	291	9	also	also	RB
cord-010570-ytv7dwr0	291	10	require	require	VB
cord-010570-ytv7dwr0	291	11	antigenic	antigenic	JJ
cord-010570-ytv7dwr0	291	12	screening	screening	NN
cord-010570-ytv7dwr0	291	13	in	in	IN
cord-010570-ytv7dwr0	291	14	the	the	DT
cord-010570-ytv7dwr0	291	15	clinical	clinical	JJ
cord-010570-ytv7dwr0	291	16	laboratory	laboratory	NN
cord-010570-ytv7dwr0	291	17	,	,	,
cord-010570-ytv7dwr0	291	18	a	a	DT
cord-010570-ytv7dwr0	291	19	practice	practice	NN
cord-010570-ytv7dwr0	291	20	not	not	RB
cord-010570-ytv7dwr0	291	21	unlike	unlike	IN
cord-010570-ytv7dwr0	291	22	the	the	DT
cord-010570-ytv7dwr0	291	23	present	present	JJ
cord-010570-ytv7dwr0	291	24	one	one	CD
cord-010570-ytv7dwr0	291	25	of	of	IN
cord-010570-ytv7dwr0	291	26	antimicrobial	antimicrobial	JJ
cord-010570-ytv7dwr0	291	27	susceptibility	susceptibility	NN
cord-010570-ytv7dwr0	291	28	testing	testing	NN
cord-010570-ytv7dwr0	291	29	.	.	.
cord-010570-ytv7dwr0	292	1	In	in	IN
cord-010570-ytv7dwr0	292	2	cost	cost	NN
cord-010570-ytv7dwr0	292	3	-	-	HYPH
cord-010570-ytv7dwr0	292	4	conscious	conscious	JJ
cord-010570-ytv7dwr0	292	5	times	time	NNS
cord-010570-ytv7dwr0	292	6	these	these	DT
cord-010570-ytv7dwr0	292	7	measures	measure	NNS
cord-010570-ytv7dwr0	292	8	may	may	MD
cord-010570-ytv7dwr0	292	9	not	not	RB
cord-010570-ytv7dwr0	292	10	immediately	immediately	RB
cord-010570-ytv7dwr0	292	11	appear	appear	VB
cord-010570-ytv7dwr0	292	12	to	to	TO
cord-010570-ytv7dwr0	292	13	be	be	VB
cord-010570-ytv7dwr0	292	14	attractive	attractive	JJ
cord-010570-ytv7dwr0	292	15	.	.	.
cord-010570-ytv7dwr0	293	1	In	in	IN
cord-010570-ytv7dwr0	293	2	this	this	DT
cord-010570-ytv7dwr0	293	3	regard	regard	NN
cord-010570-ytv7dwr0	293	4	it	-PRON-	PRP
cord-010570-ytv7dwr0	293	5	is	be	VBZ
cord-010570-ytv7dwr0	293	6	worth	worth	JJ
cord-010570-ytv7dwr0	293	7	remembering	remember	VBG
cord-010570-ytv7dwr0	293	8	that	that	IN
cord-010570-ytv7dwr0	293	9	penicillin	penicillin	NN
cord-010570-ytv7dwr0	293	10	was	be	VBD
cord-010570-ytv7dwr0	293	11	unobtainable	unobtainable	JJ
cord-010570-ytv7dwr0	293	12	in	in	IN
cord-010570-ytv7dwr0	293	13	1943	1943	CD
cord-010570-ytv7dwr0	293	14	[	[	-LRB-
cord-010570-ytv7dwr0	293	15	181	181	CD
cord-010570-ytv7dwr0	293	16	]	]	-RRB-
cord-010570-ytv7dwr0	294	1	but	but	CC
cord-010570-ytv7dwr0	294	2	half	half	PDT
cord-010570-ytv7dwr0	294	3	a	a	DT
cord-010570-ytv7dwr0	294	4	century	century	NN
cord-010570-ytv7dwr0	294	5	later	later	RBR
cord-010570-ytv7dwr0	294	6	it	-PRON-	PRP
cord-010570-ytv7dwr0	294	7	is	be	VBZ
cord-010570-ytv7dwr0	294	8	one	one	CD
cord-010570-ytv7dwr0	294	9	of	of	IN
cord-010570-ytv7dwr0	294	10	our	-PRON-	PRP$
cord-010570-ytv7dwr0	294	11	least	least	RBS
cord-010570-ytv7dwr0	294	12	-	-	HYPH
cord-010570-ytv7dwr0	294	13	expensive	expensive	JJ
cord-010570-ytv7dwr0	294	14	therapies	therapy	NNS
cord-010570-ytv7dwr0	294	15	.	.	.
cord-010570-ytv7dwr0	295	1	When	when	WRB
cord-010570-ytv7dwr0	295	2	one	one	NN
cord-010570-ytv7dwr0	295	3	is	be	VBZ
cord-010570-ytv7dwr0	295	4	reconsidering	reconsider	VBG
cord-010570-ytv7dwr0	295	5	the	the	DT
cord-010570-ytv7dwr0	295	6	option	option	NN
cord-010570-ytv7dwr0	295	7	of	of	IN
cord-010570-ytv7dwr0	295	8	antibody	antibody	NN
cord-010570-ytv7dwr0	295	9	-	-	HYPH
cord-010570-ytv7dwr0	295	10	based	base	VBN
cord-010570-ytv7dwr0	295	11	therapies	therapy	NNS
cord-010570-ytv7dwr0	295	12	,	,	,
cord-010570-ytv7dwr0	295	13	it	-PRON-	PRP
cord-010570-ytv7dwr0	295	14	is	be	VBZ
cord-010570-ytv7dwr0	295	15	important	important	JJ
cord-010570-ytv7dwr0	295	16	not	not	RB
cord-010570-ytv7dwr0	295	17	to	to	TO
cord-010570-ytv7dwr0	295	18	underestimate	underestimate	VB
cord-010570-ytv7dwr0	295	19	the	the	DT
cord-010570-ytv7dwr0	295	20	human	human	JJ
cord-010570-ytv7dwr0	295	21	capacity	capacity	NN
cord-010570-ytv7dwr0	295	22	for	for	IN
cord-010570-ytv7dwr0	295	23	improving	improve	VBG
cord-010570-ytv7dwr0	295	24	technology	technology	NN
cord-010570-ytv7dwr0	295	25	and	and	CC
cord-010570-ytv7dwr0	295	26	the	the	DT
cord-010570-ytv7dwr0	295	27	effect	effect	NN
cord-010570-ytv7dwr0	295	28	of	of	IN
cord-010570-ytv7dwr0	295	29	the	the	DT
cord-010570-ytv7dwr0	295	30	pressures	pressure	NNS
cord-010570-ytv7dwr0	295	31	of	of	IN
cord-010570-ytv7dwr0	295	32	a	a	DT
cord-010570-ytv7dwr0	295	33	competitive	competitive	JJ
cord-010570-ytv7dwr0	295	34	market	market	NN
cord-010570-ytv7dwr0	295	35	on	on	IN
cord-010570-ytv7dwr0	295	36	long	long	JJ
cord-010570-ytv7dwr0	295	37	-	-	HYPH
cord-010570-ytv7dwr0	295	38	term	term	NN
cord-010570-ytv7dwr0	295	39	costs	cost	NNS
cord-010570-ytv7dwr0	295	40	.	.	.
cord-010570-ytv7dwr0	296	1	History	history	NN
cord-010570-ytv7dwr0	296	2	of	of	IN
cord-010570-ytv7dwr0	296	3	opportunistic	opportunistic	JJ
cord-010570-ytv7dwr0	296	4	infection	infection	NN
cord-010570-ytv7dwr0	296	5	in	in	IN
cord-010570-ytv7dwr0	296	6	the	the	DT
cord-010570-ytv7dwr0	296	7	immunocompromised	immunocompromised	JJ
cord-010570-ytv7dwr0	296	8	host	host	NN
cord-010570-ytv7dwr0	296	9	New	New	NNP
cord-010570-ytv7dwr0	296	10	York	York	NNP
cord-010570-ytv7dwr0	296	11	City	City	NNP
cord-010570-ytv7dwr0	296	12	Area	Area	NNP
cord-010570-ytv7dwr0	296	13	Tuberculosis	Tuberculosis	NNP
cord-010570-ytv7dwr0	296	14	Working	Working	NNP
cord-010570-ytv7dwr0	296	15	Group	Group	NNP
cord-010570-ytv7dwr0	296	16	Management	Management	NNP
cord-010570-ytv7dwr0	296	17	of	of	IN
cord-010570-ytv7dwr0	296	18	syphilis	syphili	NNS
cord-010570-ytv7dwr0	296	19	in	in	IN
cord-010570-ytv7dwr0	296	20	human	human	JJ
cord-010570-ytv7dwr0	296	21	immunodeficiency	immunodeficiency	NN
cord-010570-ytv7dwr0	296	22	virusinfected	virusinfecte	VBD
cord-010570-ytv7dwr0	296	23	patients	patient	NNS
cord-010570-ytv7dwr0	296	24	Emerging	emerge	VBG
cord-010570-ytv7dwr0	296	25	antimicrobial	antimicrobial	JJ
cord-010570-ytv7dwr0	296	26	resistance	resistance	NN
cord-010570-ytv7dwr0	296	27	and	and	CC
cord-010570-ytv7dwr0	296	28	the	the	DT
cord-010570-ytv7dwr0	296	29	immunocompromised	immunocompromised	JJ
cord-010570-ytv7dwr0	296	30	host	host	NN
cord-010570-ytv7dwr0	296	31	Epidemiologic	epidemiologic	JJ
cord-010570-ytv7dwr0	296	32	analysis	analysis	NN
cord-010570-ytv7dwr0	296	33	and	and	CC
cord-010570-ytv7dwr0	296	34	genotypic	genotypic	JJ
cord-010570-ytv7dwr0	296	35	characterization	characterization	NN
cord-010570-ytv7dwr0	296	36	of	of	IN
cord-010570-ytv7dwr0	296	37	a	a	DT
cord-010570-ytv7dwr0	296	38	nosocomial	nosocomial	JJ
cord-010570-ytv7dwr0	296	39	outbreak	outbreak	NN
cord-010570-ytv7dwr0	296	40	of	of	IN
cord-010570-ytv7dwr0	296	41	vancomycinresistant	vancomycinresistant	JJ
cord-010570-ytv7dwr0	296	42	enterococci	enterococci	NNP
cord-010570-ytv7dwr0	296	43	Correlation	correlation	NN
cord-010570-ytv7dwr0	296	44	of	of	IN
cord-010570-ytv7dwr0	296	45	in	in	FW
cord-010570-ytv7dwr0	296	46	vitro	vitro	FW
cord-010570-ytv7dwr0	296	47	fluconazole	fluconazole	NN
cord-010570-ytv7dwr0	296	48	resistance	resistance	NN
cord-010570-ytv7dwr0	296	49	of	of	IN
cord-010570-ytv7dwr0	296	50	Candida	Candida	NNP
cord-010570-ytv7dwr0	296	51	isolates	isolate	NNS
cord-010570-ytv7dwr0	296	52	in	in	IN
cord-010570-ytv7dwr0	296	53	relation	relation	NN
cord-010570-ytv7dwr0	296	54	to	to	IN
cord-010570-ytv7dwr0	296	55	therapy	therapy	NN
cord-010570-ytv7dwr0	296	56	and	and	CC
cord-010570-ytv7dwr0	296	57	symptoms	symptom	NNS
cord-010570-ytv7dwr0	296	58	of	of	IN
cord-010570-ytv7dwr0	296	59	individuals	individual	NNS
cord-010570-ytv7dwr0	296	60	seropositive	seropositive	JJ
cord-010570-ytv7dwr0	296	61	for	for	IN
cord-010570-ytv7dwr0	296	62	human	human	JJ
cord-010570-ytv7dwr0	296	63	immunodeficiency	immunodeficiency	NN
cord-010570-ytv7dwr0	296	64	virus	virus	NN
cord-010570-ytv7dwr0	296	65	type	type	NN
cord-010570-ytv7dwr0	296	66	I	-PRON-	PRP
cord-010570-ytv7dwr0	296	67	Serum	serum	NN
cord-010570-ytv7dwr0	296	68	therapy	therapy	NN
cord-010570-ytv7dwr0	296	69	revisited	revisit	VBD
cord-010570-ytv7dwr0	296	70	:	:	:
cord-010570-ytv7dwr0	296	71	animal	animal	NN
cord-010570-ytv7dwr0	296	72	models	model	NNS
cord-010570-ytv7dwr0	296	73	of	of	IN
cord-010570-ytv7dwr0	296	74	infection	infection	NN
cord-010570-ytv7dwr0	296	75	and	and	CC
cord-010570-ytv7dwr0	296	76	development	development	NN
cord-010570-ytv7dwr0	296	77	of	of	IN
cord-010570-ytv7dwr0	296	78	passive	passive	JJ
cord-010570-ytv7dwr0	296	79	antibody	antibody	NN
cord-010570-ytv7dwr0	296	80	therapy	therapy	NN
cord-010570-ytv7dwr0	296	81	Treatment	Treatment	NNP
cord-010570-ytv7dwr0	296	82	of	of	IN
cord-010570-ytv7dwr0	296	83	Haemophilus	Haemophilus	NNP
cord-010570-ytv7dwr0	296	84	influenzae	influenzae	NN
cord-010570-ytv7dwr0	296	85	infections	infection	NNS
cord-010570-ytv7dwr0	296	86	and	and	CC
cord-010570-ytv7dwr0	296	87	of	of	IN
cord-010570-ytv7dwr0	296	88	meningococcic	meningococcic	NNP
cord-010570-ytv7dwr0	296	89	and	and	CC
cord-010570-ytv7dwr0	296	90	pneumococcic	pneumococcic	NNP
cord-010570-ytv7dwr0	296	91	meningitis	meningitis	NNP
cord-010570-ytv7dwr0	296	92	Experimental	experimental	JJ
cord-010570-ytv7dwr0	296	93	basis	basis	NN
cord-010570-ytv7dwr0	296	94	for	for	IN
cord-010570-ytv7dwr0	296	95	treatment	treatment	NN
cord-010570-ytv7dwr0	296	96	of	of	IN
cord-010570-ytv7dwr0	296	97	Haemophilus	haemophilus	JJ
cord-010570-ytv7dwr0	296	98	influenzae	influenzae	NN
cord-010570-ytv7dwr0	296	99	infections	infection	NNS
cord-010570-ytv7dwr0	296	100	Haemophilus	haemophilus	JJ
cord-010570-ytv7dwr0	296	101	influenzae	influenzae	NN
cord-010570-ytv7dwr0	296	102	(	(	-LRB-
cord-010570-ytv7dwr0	296	103	Pfeiffer	Pfeiffer	NNP
cord-010570-ytv7dwr0	296	104	bacillus	bacillus	NN
cord-010570-ytv7dwr0	296	105	)	)	-RRB-
cord-010570-ytv7dwr0	296	106	meningitis	meningitis	NN
cord-010570-ytv7dwr0	296	107	and	and	CC
cord-010570-ytv7dwr0	296	108	its	-PRON-	PRP$
cord-010570-ytv7dwr0	296	109	specific	specific	JJ
cord-010570-ytv7dwr0	296	110	treatment	treatment	NN
cord-010570-ytv7dwr0	296	111	Treatment	treatment	NN
cord-010570-ytv7dwr0	296	112	of	of	IN
cord-010570-ytv7dwr0	296	113	scarlet	scarlet	JJ
cord-010570-ytv7dwr0	296	114	fever	fever	NN
cord-010570-ytv7dwr0	296	115	and	and	CC
cord-010570-ytv7dwr0	296	116	diphtheria	diphtheria	NN
cord-010570-ytv7dwr0	296	117	The	the	DT
cord-010570-ytv7dwr0	296	118	hemolytic	hemolytic	JJ
cord-010570-ytv7dwr0	296	119	streptococci	streptococcus	NNS
cord-010570-ytv7dwr0	296	120	and	and	CC
cord-010570-ytv7dwr0	296	121	antistreptococcus	antistreptococcus	NNP
cord-010570-ytv7dwr0	296	122	serum	serum	NN
cord-010570-ytv7dwr0	296	123	in	in	IN
cord-010570-ytv7dwr0	296	124	scarlet	scarlet	JJ
cord-010570-ytv7dwr0	296	125	fever	fever	NN
cord-010570-ytv7dwr0	296	126	Therapeutic	therapeutic	JJ
cord-010570-ytv7dwr0	296	127	value	value	NN
cord-010570-ytv7dwr0	296	128	of	of	IN
cord-010570-ytv7dwr0	296	129	scarlatinal	scarlatinal	JJ
cord-010570-ytv7dwr0	296	130	antitoxin	antitoxin	NN
cord-010570-ytv7dwr0	296	131	Studies	Studies	NNPS
cord-010570-ytv7dwr0	296	132	in	in	IN
cord-010570-ytv7dwr0	296	133	scarlet	scarlet	JJ
cord-010570-ytv7dwr0	296	134	fever	fever	NN
cord-010570-ytv7dwr0	296	135	.	.	.
cord-010570-ytv7dwr0	297	1	II	II	NNP
cord-010570-ytv7dwr0	297	2	.	.	.
cord-010570-ytv7dwr0	298	1	Studies	study	NNS
cord-010570-ytv7dwr0	298	2	on	on	IN
cord-010570-ytv7dwr0	298	3	the	the	DT
cord-010570-ytv7dwr0	298	4	use	use	NN
cord-010570-ytv7dwr0	298	5	of	of	IN
cord-010570-ytv7dwr0	298	6	convalescent	convalescent	JJ
cord-010570-ytv7dwr0	298	7	scarlet	scarlet	JJ
cord-010570-ytv7dwr0	298	8	fever	fever	NN
cord-010570-ytv7dwr0	298	9	serum	serum	NN
cord-010570-ytv7dwr0	298	10	and	and	CC
cord-010570-ytv7dwr0	298	11	Dochez	Dochez	NNP
cord-010570-ytv7dwr0	298	12	'	'	POS
cord-010570-ytv7dwr0	298	13	scarlatinal	scarlatinal	JJ
cord-010570-ytv7dwr0	298	14	antistreptococcic	antistreptococcic	NNP
cord-010570-ytv7dwr0	298	15	serum	serum	NN
cord-010570-ytv7dwr0	298	16	for	for	IN
cord-010570-ytv7dwr0	298	17	the	the	DT
cord-010570-ytv7dwr0	298	18	treatment	treatment	NN
cord-010570-ytv7dwr0	298	19	of	of	IN
cord-010570-ytv7dwr0	298	20	scarlet	scarlet	JJ
cord-010570-ytv7dwr0	298	21	fever	fever	NN
cord-010570-ytv7dwr0	299	1	The	the	DT
cord-010570-ytv7dwr0	299	2	etiology	etiology	NN
cord-010570-ytv7dwr0	299	3	of	of	IN
cord-010570-ytv7dwr0	299	4	erysipelas	erysipela	NNS
cord-010570-ytv7dwr0	299	5	Treatment	treatment	NN
cord-010570-ytv7dwr0	299	6	of	of	IN
cord-010570-ytv7dwr0	299	7	whooping	whooping	JJ
cord-010570-ytv7dwr0	299	8	cough	cough	NN
cord-010570-ytv7dwr0	299	9	bronchopneumonia	bronchopneumonia	NN
cord-010570-ytv7dwr0	299	10	Therapeutic	therapeutic	JJ
cord-010570-ytv7dwr0	299	11	procedures	procedure	NNS
cord-010570-ytv7dwr0	299	12	for	for	IN
cord-010570-ytv7dwr0	299	13	scarlet	scarlet	JJ
cord-010570-ytv7dwr0	299	14	fever	fever	NN
cord-010570-ytv7dwr0	299	15	:	:	:
cord-010570-ytv7dwr0	299	16	comparative	comparative	JJ
cord-010570-ytv7dwr0	299	17	studies	study	NNS
cord-010570-ytv7dwr0	300	1	Hyperimmune	Hyperimmune	NNP
cord-010570-ytv7dwr0	300	2	whooping	whooping	JJ
cord-010570-ytv7dwr0	300	3	cough	cough	NN
cord-010570-ytv7dwr0	300	4	serum	serum	NN
cord-010570-ytv7dwr0	300	5	:	:	:
cord-010570-ytv7dwr0	301	1	further	further	JJ
cord-010570-ytv7dwr0	301	2	studies	study	NNS
cord-010570-ytv7dwr0	302	1	The	the	DT
cord-010570-ytv7dwr0	302	2	treatment	treatment	NN
cord-010570-ytv7dwr0	302	3	of	of	IN
cord-010570-ytv7dwr0	302	4	pertussis	pertussis	NN
cord-010570-ytv7dwr0	302	5	with	with	IN
cord-010570-ytv7dwr0	302	6	lyophile	lyophile	NNP
cord-010570-ytv7dwr0	302	7	hyperimmune	hyperimmune	NNP
cord-010570-ytv7dwr0	302	8	human	human	NNP
cord-010570-ytv7dwr0	302	9	pertussis	pertussis	NNP
cord-010570-ytv7dwr0	302	10	serum	serum	NN
cord-010570-ytv7dwr0	302	11	Serum	serum	NN
cord-010570-ytv7dwr0	302	12	in	in	IN
cord-010570-ytv7dwr0	302	13	the	the	DT
cord-010570-ytv7dwr0	302	14	prophylaxis	prophylaxis	NN
cord-010570-ytv7dwr0	302	15	of	of	IN
cord-010570-ytv7dwr0	302	16	contacts	contact	NNS
cord-010570-ytv7dwr0	302	17	and	and	CC
cord-010570-ytv7dwr0	302	18	the	the	DT
cord-010570-ytv7dwr0	302	19	treatment	treatment	NN
cord-010570-ytv7dwr0	302	20	of	of	IN
cord-010570-ytv7dwr0	302	21	whooping	whooping	JJ
cord-010570-ytv7dwr0	302	22	cough	cough	NN
cord-010570-ytv7dwr0	303	1	The	the	DT
cord-010570-ytv7dwr0	303	2	treatment	treatment	NN
cord-010570-ytv7dwr0	303	3	of	of	IN
cord-010570-ytv7dwr0	303	4	anthrax	anthrax	NN
cord-010570-ytv7dwr0	303	5	Equine	equine	JJ
cord-010570-ytv7dwr0	303	6	antitoxin	antitoxin	NN
cord-010570-ytv7dwr0	303	7	use	use	NN
cord-010570-ytv7dwr0	303	8	and	and	CC
cord-010570-ytv7dwr0	303	9	other	other	JJ
cord-010570-ytv7dwr0	303	10	factors	factor	NNS
cord-010570-ytv7dwr0	303	11	that	that	WDT
cord-010570-ytv7dwr0	303	12	predict	predict	VBP
cord-010570-ytv7dwr0	303	13	outcome	outcome	NN
cord-010570-ytv7dwr0	303	14	in	in	IN
cord-010570-ytv7dwr0	303	15	type	type	NN
cord-010570-ytv7dwr0	303	16	A	a	NN
cord-010570-ytv7dwr0	304	1	foodborne	foodborne	JJ
cord-010570-ytv7dwr0	304	2	botulism	botulism	NN
cord-010570-ytv7dwr0	304	3	Allergy	allergy	NN
cord-010570-ytv7dwr0	304	4	:	:	:
cord-010570-ytv7dwr0	304	5	serum	serum	NN
cord-010570-ytv7dwr0	304	6	reactions	reaction	NNS
cord-010570-ytv7dwr0	304	7	,	,	,
cord-010570-ytv7dwr0	304	8	with	with	IN
cord-010570-ytv7dwr0	304	9	particular	particular	JJ
cord-010570-ytv7dwr0	304	10	reference	reference	NN
cord-010570-ytv7dwr0	304	11	to	to	IN
cord-010570-ytv7dwr0	304	12	the	the	DT
cord-010570-ytv7dwr0	304	13	prevention	prevention	NN
cord-010570-ytv7dwr0	304	14	and	and	CC
cord-010570-ytv7dwr0	304	15	treatment	treatment	NN
cord-010570-ytv7dwr0	304	16	of	of	IN
cord-010570-ytv7dwr0	304	17	tetanus	tetanus	NN
cord-010570-ytv7dwr0	304	18	Therapy	therapy	NN
cord-010570-ytv7dwr0	304	19	of	of	IN
cord-010570-ytv7dwr0	304	20	tetanus	tetanus	NN
cord-010570-ytv7dwr0	304	21	.	.	.
cord-010570-ytv7dwr0	305	1	A	a	DT
cord-010570-ytv7dwr0	305	2	study	study	NN
cord-010570-ytv7dwr0	305	3	of	of	IN
cord-010570-ytv7dwr0	305	4	two	two	CD
cord-010570-ytv7dwr0	305	5	hundred	hundred	CD
cord-010570-ytv7dwr0	305	6	and	and	CC
cord-010570-ytv7dwr0	305	7	seventy	seventy	CD
cord-010570-ytv7dwr0	305	8	-	-	HYPH
cord-010570-ytv7dwr0	305	9	six	six	CD
cord-010570-ytv7dwr0	305	10	cases	case	NNS
cord-010570-ytv7dwr0	306	1	The	the	DT
cord-010570-ytv7dwr0	306	2	treatment	treatment	NN
cord-010570-ytv7dwr0	306	3	of	of	IN
cord-010570-ytv7dwr0	306	4	human	human	JJ
cord-010570-ytv7dwr0	306	5	brucellosis	brucellosis	NN
cord-010570-ytv7dwr0	306	6	.	.	.
cord-010570-ytv7dwr0	307	1	A	a	DT
cord-010570-ytv7dwr0	307	2	review	review	NN
cord-010570-ytv7dwr0	307	3	of	of	IN
cord-010570-ytv7dwr0	307	4	current	current	JJ
cord-010570-ytv7dwr0	307	5	therapeutic	therapeutic	JJ
cord-010570-ytv7dwr0	307	6	methods	method	NNS
cord-010570-ytv7dwr0	307	7	Some	some	DT
cord-010570-ytv7dwr0	307	8	points	point	NNS
cord-010570-ytv7dwr0	307	9	in	in	IN
cord-010570-ytv7dwr0	307	10	the	the	DT
cord-010570-ytv7dwr0	307	11	diagnosis	diagnosis	NN
cord-010570-ytv7dwr0	307	12	and	and	CC
cord-010570-ytv7dwr0	307	13	treatment	treatment	NN
cord-010570-ytv7dwr0	307	14	of	of	IN
cord-010570-ytv7dwr0	307	15	dysentery	dysentery	NN
cord-010570-ytv7dwr0	307	16	occurring	occur	VBG
cord-010570-ytv7dwr0	307	17	in	in	IN
cord-010570-ytv7dwr0	307	18	the	the	DT
cord-010570-ytv7dwr0	307	19	British	british	JJ
cord-010570-ytv7dwr0	307	20	Salonika	Salonika	NNP
cord-010570-ytv7dwr0	307	21	force	force	NN
cord-010570-ytv7dwr0	308	1	The	the	DT
cord-010570-ytv7dwr0	308	2	dysenteric	dysenteric	JJ
cord-010570-ytv7dwr0	308	3	disorders	disorder	NNS
cord-010570-ytv7dwr0	308	4	.	.	.
cord-010570-ytv7dwr0	309	1	In	in	IN
cord-010570-ytv7dwr0	309	2	:	:	:
cord-010570-ytv7dwr0	309	3	The	the	DT
cord-010570-ytv7dwr0	309	4	diagnosis	diagnosis	NN
cord-010570-ytv7dwr0	309	5	and	and	CC
cord-010570-ytv7dwr0	309	6	treatment	treatment	NN
cord-010570-ytv7dwr0	309	7	of	of	IN
cord-010570-ytv7dwr0	309	8	dysentery	dysentery	NN
cord-010570-ytv7dwr0	309	9	,	,	,
cord-010570-ytv7dwr0	309	10	sprue	sprue	NN
cord-010570-ytv7dwr0	309	11	,	,	,
cord-010570-ytv7dwr0	309	12	colitis	colitis	NN
cord-010570-ytv7dwr0	309	13	,	,	,
cord-010570-ytv7dwr0	309	14	and	and	CC
cord-010570-ytv7dwr0	309	15	other	other	JJ
cord-010570-ytv7dwr0	309	16	diarrhoeas	diarrhoea	NNS
cord-010570-ytv7dwr0	309	17	in	in	IN
cord-010570-ytv7dwr0	309	18	general	general	JJ
cord-010570-ytv7dwr0	309	19	practice	practice	NN
cord-010570-ytv7dwr0	309	20	Tularemia	Tularemia	NNP
cord-010570-ytv7dwr0	309	21	:	:	:
cord-010570-ytv7dwr0	309	22	a	a	DT
cord-010570-ytv7dwr0	309	23	summary	summary	NN
cord-010570-ytv7dwr0	309	24	of	of	IN
cord-010570-ytv7dwr0	309	25	certain	certain	JJ
cord-010570-ytv7dwr0	309	26	aspects	aspect	NNS
cord-010570-ytv7dwr0	309	27	of	of	IN
cord-010570-ytv7dwr0	309	28	the	the	DT
cord-010570-ytv7dwr0	309	29	disease	disease	NN
cord-010570-ytv7dwr0	309	30	including	include	VBG
cord-010570-ytv7dwr0	309	31	methods	method	NNS
cord-010570-ytv7dwr0	309	32	for	for	IN
cord-010570-ytv7dwr0	309	33	early	early	JJ
cord-010570-ytv7dwr0	309	34	diagnosis	diagnosis	NN
cord-010570-ytv7dwr0	309	35	and	and	CC
cord-010570-ytv7dwr0	309	36	the	the	DT
cord-010570-ytv7dwr0	309	37	results	result	NNS
cord-010570-ytv7dwr0	309	38	of	of	IN
cord-010570-ytv7dwr0	309	39	serum	serum	NN
cord-010570-ytv7dwr0	309	40	treatment	treatment	NN
cord-010570-ytv7dwr0	309	41	in	in	IN
cord-010570-ytv7dwr0	309	42	600	600	CD
cord-010570-ytv7dwr0	309	43	patients	patient	NNS
cord-010570-ytv7dwr0	309	44	Use	Use	NNP
cord-010570-ytv7dwr0	309	45	of	of	IN
cord-010570-ytv7dwr0	309	46	convalescent	convalescent	JJ
cord-010570-ytv7dwr0	309	47	measles	measles	NN
cord-010570-ytv7dwr0	309	48	serum	serum	NN
cord-010570-ytv7dwr0	309	49	to	to	TO
cord-010570-ytv7dwr0	309	50	control	control	VB
cord-010570-ytv7dwr0	309	51	measles	measle	NNS
cord-010570-ytv7dwr0	309	52	in	in	IN
cord-010570-ytv7dwr0	309	53	a	a	DT
cord-010570-ytv7dwr0	309	54	preparatory	preparatory	JJ
cord-010570-ytv7dwr0	309	55	school	school	NN
cord-010570-ytv7dwr0	310	1	Convalescent	convalescent	JJ
cord-010570-ytv7dwr0	310	2	whole	whole	JJ
cord-010570-ytv7dwr0	310	3	blood	blood	NN
cord-010570-ytv7dwr0	310	4	,	,	,
cord-010570-ytv7dwr0	310	5	plasma	plasma	NN
cord-010570-ytv7dwr0	310	6	and	and	CC
cord-010570-ytv7dwr0	310	7	serum	serum	NN
cord-010570-ytv7dwr0	310	8	in	in	IN
cord-010570-ytv7dwr0	310	9	prophylaxis	prophylaxis	NN
cord-010570-ytv7dwr0	310	10	of	of	IN
cord-010570-ytv7dwr0	310	11	measles	measle	NNS
cord-010570-ytv7dwr0	311	1	The	the	DT
cord-010570-ytv7dwr0	311	2	prophylactic	prophylactic	JJ
cord-010570-ytv7dwr0	311	3	use	use	NN
cord-010570-ytv7dwr0	311	4	of	of	IN
cord-010570-ytv7dwr0	311	5	measles	measles	NNP
cord-010570-ytv7dwr0	311	6	convalescent	convalescent	NNP
cord-010570-ytv7dwr0	311	7	serum	serum	NNP
cord-010570-ytv7dwr0	311	8	Park	Park	NNP
cord-010570-ytv7dwr0	311	9	WHo	WHo	VBD
cord-010570-ytv7dwr0	311	10	Therapeutic	therapeutic	JJ
cord-010570-ytv7dwr0	311	11	use	use	NN
cord-010570-ytv7dwr0	311	12	of	of	IN
cord-010570-ytv7dwr0	311	13	antipoliomyelitis	antipoliomyelitis	JJ
cord-010570-ytv7dwr0	311	14	serum	serum	NN
cord-010570-ytv7dwr0	311	15	in	in	IN
cord-010570-ytv7dwr0	311	16	preparalytic	preparalytic	JJ
cord-010570-ytv7dwr0	311	17	cases	case	NNS
cord-010570-ytv7dwr0	311	18	of	of	IN
cord-010570-ytv7dwr0	311	19	poliomyelitis	poliomyelitis	NN
cord-010570-ytv7dwr0	312	1	The	the	DT
cord-010570-ytv7dwr0	312	2	use	use	NN
cord-010570-ytv7dwr0	312	3	of	of	IN
cord-010570-ytv7dwr0	312	4	convalescent	convalescent	JJ
cord-010570-ytv7dwr0	312	5	serum	serum	NN
cord-010570-ytv7dwr0	312	6	in	in	IN
cord-010570-ytv7dwr0	312	7	the	the	DT
cord-010570-ytv7dwr0	312	8	treatment	treatment	NN
cord-010570-ytv7dwr0	312	9	of	of	IN
cord-010570-ytv7dwr0	312	10	measles	measle	NNS
cord-010570-ytv7dwr0	312	11	,	,	,
cord-010570-ytv7dwr0	312	12	chicken	chicken	NN
cord-010570-ytv7dwr0	312	13	-	-	HYPH
cord-010570-ytv7dwr0	312	14	pox	pox	NN
cord-010570-ytv7dwr0	312	15	,	,	,
cord-010570-ytv7dwr0	312	16	mumps	mumps	NN
cord-010570-ytv7dwr0	312	17	and	and	CC
cord-010570-ytv7dwr0	312	18	whooping	whooping	JJ
cord-010570-ytv7dwr0	312	19	cough	cough	NN
cord-010570-ytv7dwr0	312	20	,	,	,
cord-010570-ytv7dwr0	312	21	including	include	VBG
cord-010570-ytv7dwr0	312	22	the	the	DT
cord-010570-ytv7dwr0	312	23	prophylactic	prophylactic	JJ
cord-010570-ytv7dwr0	312	24	value	value	NN
cord-010570-ytv7dwr0	312	25	of	of	IN
cord-010570-ytv7dwr0	312	26	parental	parental	JJ
cord-010570-ytv7dwr0	312	27	blood	blood	NN
cord-010570-ytv7dwr0	313	1	The	the	DT
cord-010570-ytv7dwr0	313	2	prophylaxis	prophylaxis	NN
cord-010570-ytv7dwr0	313	3	of	of	IN
cord-010570-ytv7dwr0	313	4	varicella	varicella	NN
cord-010570-ytv7dwr0	313	5	with	with	IN
cord-010570-ytv7dwr0	313	6	convalescents	convalescent	NNS
cord-010570-ytv7dwr0	313	7	'	'	POS
cord-010570-ytv7dwr0	313	8	serum	serum	NN
cord-010570-ytv7dwr0	313	9	Specific	specific	JJ
cord-010570-ytv7dwr0	313	10	treatment	treatment	NN
cord-010570-ytv7dwr0	313	11	of	of	IN
cord-010570-ytv7dwr0	313	12	pneumococcus	pneumococcus	NNP
cord-010570-ytv7dwr0	313	13	Type	Type	NNP
cord-010570-ytv7dwr0	313	14	I	i	CD
cord-010570-ytv7dwr0	313	15	pneumonia	pneumonia	NN
cord-010570-ytv7dwr0	313	16	.	.	.
cord-010570-ytv7dwr0	314	1	Including	include	VBG
cord-010570-ytv7dwr0	314	2	the	the	DT
cord-010570-ytv7dwr0	314	3	use	use	NN
cord-010570-ytv7dwr0	314	4	of	of	IN
cord-010570-ytv7dwr0	314	5	horse	horse	NN
cord-010570-ytv7dwr0	314	6	and	and	CC
cord-010570-ytv7dwr0	314	7	rabbit	rabbit	NN
cord-010570-ytv7dwr0	314	8	antipneumococcus	antipneumococcus	NN
cord-010570-ytv7dwr0	314	9	serums	serum	NNS
cord-010570-ytv7dwr0	314	10	and	and	CC
cord-010570-ytv7dwr0	314	11	sulphanilamide	sulphanilamide	VB
cord-010570-ytv7dwr0	314	12	The	the	DT
cord-010570-ytv7dwr0	314	13	antitoxin	antitoxin	NN
cord-010570-ytv7dwr0	314	14	treatment	treatment	NN
cord-010570-ytv7dwr0	314	15	of	of	IN
cord-010570-ytv7dwr0	314	16	erysipelas	erysipela	NNS
cord-010570-ytv7dwr0	314	17	:	:	:
cord-010570-ytv7dwr0	314	18	further	further	JJ
cord-010570-ytv7dwr0	314	19	observations	observation	NNS
cord-010570-ytv7dwr0	315	1	The	the	DT
cord-010570-ytv7dwr0	315	2	results	result	NNS
cord-010570-ytv7dwr0	315	3	of	of	IN
cord-010570-ytv7dwr0	315	4	the	the	DT
cord-010570-ytv7dwr0	315	5	serum	serum	NN
cord-010570-ytv7dwr0	315	6	treatment	treatment	NN
cord-010570-ytv7dwr0	315	7	in	in	IN
cord-010570-ytv7dwr0	315	8	thirteen	thirteen	CD
cord-010570-ytv7dwr0	315	9	hundred	hundred	CD
cord-010570-ytv7dwr0	315	10	cases	case	NNS
cord-010570-ytv7dwr0	315	11	of	of	IN
cord-010570-ytv7dwr0	315	12	epidemic	epidemic	NN
cord-010570-ytv7dwr0	315	13	meningitis	meningitis	NN
cord-010570-ytv7dwr0	315	14	Antitoxin	antitoxin	NN
cord-010570-ytv7dwr0	315	15	versus	versus	IN
cord-010570-ytv7dwr0	315	16	no	no	DT
cord-010570-ytv7dwr0	315	17	antitoxin	antitoxin	NN
cord-010570-ytv7dwr0	315	18	in	in	IN
cord-010570-ytv7dwr0	315	19	scarlet	scarlet	JJ
cord-010570-ytv7dwr0	315	20	fever	fever	NN
cord-010570-ytv7dwr0	315	21	Principles	principle	NNS
cord-010570-ytv7dwr0	315	22	and	and	CC
cord-010570-ytv7dwr0	315	23	practice	practice	NN
cord-010570-ytv7dwr0	315	24	of	of	IN
cord-010570-ytv7dwr0	315	25	infectious	infectious	JJ
cord-010570-ytv7dwr0	315	26	diseases	disease	NNS
cord-010570-ytv7dwr0	316	1	Some	some	DT
cord-010570-ytv7dwr0	316	2	recent	recent	JJ
cord-010570-ytv7dwr0	316	3	advances	advance	NNS
cord-010570-ytv7dwr0	316	4	in	in	IN
cord-010570-ytv7dwr0	316	5	vaccines	vaccine	NNS
cord-010570-ytv7dwr0	316	6	and	and	CC
cord-010570-ytv7dwr0	316	7	serums	serum	NNS
cord-010570-ytv7dwr0	316	8	:	:	:
cord-010570-ytv7dwr0	316	9	a	a	DT
cord-010570-ytv7dwr0	316	10	review	review	NN
cord-010570-ytv7dwr0	317	1	The	the	DT
cord-010570-ytv7dwr0	317	2	principles	principle	NNS
cord-010570-ytv7dwr0	317	3	and	and	CC
cord-010570-ytv7dwr0	317	4	practice	practice	NN
cord-010570-ytv7dwr0	317	5	of	of	IN
cord-010570-ytv7dwr0	317	6	medicine	medicine	NN
cord-010570-ytv7dwr0	318	1	A	a	DT
cord-010570-ytv7dwr0	318	2	brief	brief	JJ
cord-010570-ytv7dwr0	318	3	history	history	NN
cord-010570-ytv7dwr0	318	4	of	of	IN
cord-010570-ytv7dwr0	318	5	the	the	DT
cord-010570-ytv7dwr0	318	6	pneumococcus	pneumococcus	NN
cord-010570-ytv7dwr0	318	7	in	in	IN
cord-010570-ytv7dwr0	318	8	biomedical	biomedical	JJ
cord-010570-ytv7dwr0	318	9	research	research	NN
cord-010570-ytv7dwr0	318	10	:	:	:
cord-010570-ytv7dwr0	318	11	a	a	DT
cord-010570-ytv7dwr0	318	12	panoply	panoply	NN
cord-010570-ytv7dwr0	318	13	of	of	IN
cord-010570-ytv7dwr0	318	14	scientific	scientific	JJ
cord-010570-ytv7dwr0	318	15	discovery	discovery	NN
cord-010570-ytv7dwr0	318	16	Progress	Progress	NNP
cord-010570-ytv7dwr0	318	17	in	in	IN
cord-010570-ytv7dwr0	318	18	chemotherapy	chemotherapy	NN
cord-010570-ytv7dwr0	318	19	of	of	IN
cord-010570-ytv7dwr0	318	20	bacterial	bacterial	JJ
cord-010570-ytv7dwr0	318	21	and	and	CC
cord-010570-ytv7dwr0	318	22	other	other	JJ
cord-010570-ytv7dwr0	318	23	diseases	disease	NNS
cord-010570-ytv7dwr0	318	24	;	;	:
cord-010570-ytv7dwr0	318	25	with	with	IN
cord-010570-ytv7dwr0	318	26	special	special	JJ
cord-010570-ytv7dwr0	318	27	reference	reference	NN
cord-010570-ytv7dwr0	318	28	to	to	IN
cord-010570-ytv7dwr0	318	29	the	the	DT
cord-010570-ytv7dwr0	318	30	prontosils	prontosil	NNS
cord-010570-ytv7dwr0	318	31	,	,	,
cord-010570-ytv7dwr0	318	32	sulfanilamide	sulfanilamide	NN
cord-010570-ytv7dwr0	318	33	and	and	CC
cord-010570-ytv7dwr0	318	34	sulfapyridine	sulfapyridine	NNP
cord-010570-ytv7dwr0	319	1	The	the	DT
cord-010570-ytv7dwr0	319	2	therapy	therapy	NN
cord-010570-ytv7dwr0	319	3	of	of	IN
cord-010570-ytv7dwr0	319	4	(	(	-LRB-
cord-010570-ytv7dwr0	319	5	horse	horse	NN
cord-010570-ytv7dwr0	319	6	)	)	-RRB-
cord-010570-ytv7dwr0	319	7	serum	serum	NN
cord-010570-ytv7dwr0	319	8	reactions	reaction	NNS
cord-010570-ytv7dwr0	319	9	:	:	:
cord-010570-ytv7dwr0	319	10	general	general	JJ
cord-010570-ytv7dwr0	319	11	rules	rule	NNS
cord-010570-ytv7dwr0	319	12	in	in	IN
cord-010570-ytv7dwr0	319	13	the	the	DT
cord-010570-ytv7dwr0	319	14	administration	administration	NN
cord-010570-ytv7dwr0	319	15	of	of	IN
cord-010570-ytv7dwr0	319	16	therapeutic	therapeutic	JJ
cord-010570-ytv7dwr0	319	17	serums	serum	NNS
cord-010570-ytv7dwr0	320	1	The	the	DT
cord-010570-ytv7dwr0	320	2	units	unit	NNS
cord-010570-ytv7dwr0	320	3	of	of	IN
cord-010570-ytv7dwr0	320	4	protective	protective	JJ
cord-010570-ytv7dwr0	320	5	antibody	antibody	NN
cord-010570-ytv7dwr0	320	6	in	in	IN
cord-010570-ytv7dwr0	320	7	anti	anti	JJ
cord-010570-ytv7dwr0	320	8	-	-	JJ
cord-010570-ytv7dwr0	320	9	pneumococcus	pneumococcus	JJ
cord-010570-ytv7dwr0	320	10	serum	serum	NN
cord-010570-ytv7dwr0	320	11	and	and	CC
cord-010570-ytv7dwr0	320	12	antibody	antibody	NN
cord-010570-ytv7dwr0	320	13	solution	solution	NN
cord-010570-ytv7dwr0	321	1	The	the	DT
cord-010570-ytv7dwr0	321	2	use	use	NN
cord-010570-ytv7dwr0	321	3	of	of	IN
cord-010570-ytv7dwr0	321	4	serum	serum	NN
cord-010570-ytv7dwr0	321	5	,	,	,
cord-010570-ytv7dwr0	321	6	sulfanilamide	sulfanilamide	NN
cord-010570-ytv7dwr0	321	7	,	,	,
cord-010570-ytv7dwr0	321	8	and	and	CC
cord-010570-ytv7dwr0	321	9	sulfapyridine	sulfapyridine	NN
cord-010570-ytv7dwr0	321	10	in	in	IN
cord-010570-ytv7dwr0	321	11	the	the	DT
cord-010570-ytv7dwr0	321	12	treatment	treatment	NN
cord-010570-ytv7dwr0	321	13	of	of	IN
cord-010570-ytv7dwr0	321	14	pneumococcic	pneumococcic	NN
cord-010570-ytv7dwr0	321	15	infections	infection	NNS
cord-010570-ytv7dwr0	322	1	The	the	DT
cord-010570-ytv7dwr0	322	2	results	result	NNS
cord-010570-ytv7dwr0	322	3	of	of	IN
cord-010570-ytv7dwr0	322	4	sulfapyridine	sulfapyridine	NN
cord-010570-ytv7dwr0	322	5	therapy	therapy	NN
cord-010570-ytv7dwr0	322	6	in	in	IN
cord-010570-ytv7dwr0	322	7	400	400	CD
cord-010570-ytv7dwr0	322	8	cases	case	NNS
cord-010570-ytv7dwr0	322	9	of	of	IN
cord-010570-ytv7dwr0	322	10	typed	type	VBN
cord-010570-ytv7dwr0	322	11	pneumococcic	pneumococcic	NNP
cord-010570-ytv7dwr0	322	12	pneumonia	pneumonia	NN
cord-010570-ytv7dwr0	322	13	Sulfanilamide	Sulfanilamide	NNP
cord-010570-ytv7dwr0	322	14	treatment	treatment	NN
cord-010570-ytv7dwr0	322	15	of	of	IN
cord-010570-ytv7dwr0	322	16	erysipelas	erysipela	NNS
cord-010570-ytv7dwr0	322	17	Sulfanilamide	Sulfanilamide	NNP
cord-010570-ytv7dwr0	322	18	in	in	IN
cord-010570-ytv7dwr0	322	19	the	the	DT
cord-010570-ytv7dwr0	322	20	treatment	treatment	NN
cord-010570-ytv7dwr0	322	21	of	of	IN
cord-010570-ytv7dwr0	322	22	106	106	CD
cord-010570-ytv7dwr0	322	23	patients	patient	NNS
cord-010570-ytv7dwr0	322	24	with	with	IN
cord-010570-ytv7dwr0	322	25	meningococcic	meningococcic	NN
cord-010570-ytv7dwr0	322	26	infections	infection	NNS
cord-010570-ytv7dwr0	323	1	The	the	DT
cord-010570-ytv7dwr0	323	2	treatment	treatment	NN
cord-010570-ytv7dwr0	323	3	of	of	IN
cord-010570-ytv7dwr0	323	4	pneumococcus	pneumococcus	NNP
cord-010570-ytv7dwr0	323	5	pneumonia	pneumonia	NN
cord-010570-ytv7dwr0	323	6	:	:	:
cord-010570-ytv7dwr0	323	7	a	a	DT
cord-010570-ytv7dwr0	323	8	comparison	comparison	NN
cord-010570-ytv7dwr0	323	9	of	of	IN
cord-010570-ytv7dwr0	323	10	the	the	DT
cord-010570-ytv7dwr0	323	11	results	result	NNS
cord-010570-ytv7dwr0	323	12	obtained	obtain	VBN
cord-010570-ytv7dwr0	323	13	with	with	IN
cord-010570-ytv7dwr0	323	14	specific	specific	JJ
cord-010570-ytv7dwr0	323	15	serum	serum	NN
cord-010570-ytv7dwr0	323	16	and	and	CC
cord-010570-ytv7dwr0	323	17	with	with	IN
cord-010570-ytv7dwr0	323	18	sulfapyridine	sulfapyridine	NNP
cord-010570-ytv7dwr0	323	19	Sulfapyridine	Sulfapyridine	NNP
cord-010570-ytv7dwr0	323	20	and	and	CC
cord-010570-ytv7dwr0	323	21	serum	serum	NN
cord-010570-ytv7dwr0	323	22	therapy	therapy	NN
cord-010570-ytv7dwr0	323	23	in	in	IN
cord-010570-ytv7dwr0	323	24	experimental	experimental	JJ
cord-010570-ytv7dwr0	323	25	lobar	lobar	NN
cord-010570-ytv7dwr0	323	26	pneumonia	pneumonia	NN
cord-010570-ytv7dwr0	323	27	of	of	IN
cord-010570-ytv7dwr0	323	28	rats	rat	NNS
cord-010570-ytv7dwr0	323	29	P	p	NN
cord-010570-ytv7dwr0	323	30	-	-	HYPH
cord-010570-ytv7dwr0	323	31	aminobenzenesulfonamide	aminobenzenesulfonamide	JJ
cord-010570-ytv7dwr0	323	32	and	and	CC
cord-010570-ytv7dwr0	323	33	antipneumococcal	antipneumococcal	JJ
cord-010570-ytv7dwr0	323	34	serum	serum	NN
cord-010570-ytv7dwr0	323	35	therapy	therapy	NN
cord-010570-ytv7dwr0	323	36	in	in	IN
cord-010570-ytv7dwr0	323	37	type	type	NN
cord-010570-ytv7dwr0	324	1	I	-PRON-	PRP
cord-010570-ytv7dwr0	324	2	pneumococcal	pneumococcal	JJ
cord-010570-ytv7dwr0	324	3	infections	infection	NNS
cord-010570-ytv7dwr0	324	4	of	of	IN
cord-010570-ytv7dwr0	324	5	rats	rat	NNS
cord-010570-ytv7dwr0	324	6	Chemotherapy	Chemotherapy	NNP
cord-010570-ytv7dwr0	324	7	of	of	IN
cord-010570-ytv7dwr0	324	8	pneumococcic	pneumococcic	NNP
cord-010570-ytv7dwr0	324	9	pneumonia	pneumonia	NN
cord-010570-ytv7dwr0	324	10	.	.	.
cord-010570-ytv7dwr0	325	1	Clinical	clinical	JJ
cord-010570-ytv7dwr0	325	2	leeture	leeture	NN
cord-010570-ytv7dwr0	325	3	at	at	IN
cord-010570-ytv7dwr0	325	4	S1	S1	NNP
cord-010570-ytv7dwr0	325	5	.	.	.
cord-010570-ytv7dwr0	326	1	Louis	Louis	NNP
cord-010570-ytv7dwr0	326	2	session	session	NN
cord-010570-ytv7dwr0	326	3	Combined	combine	VBN
cord-010570-ytv7dwr0	326	4	therapy	therapy	NN
cord-010570-ytv7dwr0	326	5	of	of	IN
cord-010570-ytv7dwr0	326	6	pneumococcic	pneumococcic	NNP
cord-010570-ytv7dwr0	326	7	rat	rat	NNP
cord-010570-ytv7dwr0	326	8	infections	infection	NNS
cord-010570-ytv7dwr0	326	9	with	with	IN
cord-010570-ytv7dwr0	326	10	rabbit	rabbit	NN
cord-010570-ytv7dwr0	326	11	antipneumococcic	antipneumococcic	NNP
cord-010570-ytv7dwr0	326	12	serum	serum	NNP
cord-010570-ytv7dwr0	326	13	and	and	CC
cord-010570-ytv7dwr0	326	14	sulfapyridine	sulfapyridine	NNP
cord-010570-ytv7dwr0	326	15	(	(	-LRB-
cord-010570-ytv7dwr0	326	16	2-sulfanilyl	2-sulfanilyl	CD
cord-010570-ytv7dwr0	326	17	aminopyridine	aminopyridine	NN
cord-010570-ytv7dwr0	326	18	)	)	-RRB-
cord-010570-ytv7dwr0	327	1	The	the	DT
cord-010570-ytv7dwr0	327	2	treatment	treatment	NN
cord-010570-ytv7dwr0	327	3	of	of	IN
cord-010570-ytv7dwr0	327	4	bacterial	bacterial	JJ
cord-010570-ytv7dwr0	327	5	infections	infection	NNS
cord-010570-ytv7dwr0	327	6	with	with	IN
cord-010570-ytv7dwr0	327	7	the	the	DT
cord-010570-ytv7dwr0	327	8	combination	combination	NN
cord-010570-ytv7dwr0	327	9	of	of	IN
cord-010570-ytv7dwr0	327	10	antibiotics	antibiotic	NNS
cord-010570-ytv7dwr0	327	11	and	and	CC
cord-010570-ytv7dwr0	327	12	gamma	gamma	NN
cord-010570-ytv7dwr0	327	13	globulin	globulin	NN
cord-010570-ytv7dwr0	327	14	Sulphanilamide	Sulphanilamide	NNP
cord-010570-ytv7dwr0	327	15	,	,	,
cord-010570-ytv7dwr0	327	16	serum	serum	NN
cord-010570-ytv7dwr0	327	17	,	,	,
cord-010570-ytv7dwr0	327	18	and	and	CC
cord-010570-ytv7dwr0	327	19	combined	combine	VBN
cord-010570-ytv7dwr0	327	20	drug	drug	NN
cord-010570-ytv7dwr0	327	21	and	and	CC
cord-010570-ytv7dwr0	327	22	serum	serum	NN
cord-010570-ytv7dwr0	327	23	therapy	therapy	NN
cord-010570-ytv7dwr0	327	24	in	in	IN
cord-010570-ytv7dwr0	327	25	experimental	experimental	JJ
cord-010570-ytv7dwr0	327	26	meningococcus	meningococcus	NNP
cord-010570-ytv7dwr0	327	27	and	and	CC
cord-010570-ytv7dwr0	327	28	pneumococcus	pneumococcus	JJ
cord-010570-ytv7dwr0	327	29	infections	infection	NNS
cord-010570-ytv7dwr0	327	30	in	in	IN
cord-010570-ytv7dwr0	327	31	mice	mouse	NNS
cord-010570-ytv7dwr0	328	1	The	the	DT
cord-010570-ytv7dwr0	328	2	action	action	NN
cord-010570-ytv7dwr0	328	3	of	of	IN
cord-010570-ytv7dwr0	328	4	prontosil	prontosil	NN
cord-010570-ytv7dwr0	328	5	-	-	HYPH
cord-010570-ytv7dwr0	328	6	soluble	soluble	JJ
cord-010570-ytv7dwr0	328	7	and	and	CC
cord-010570-ytv7dwr0	328	8	sulfanilamide	sulfanilamide	NN
cord-010570-ytv7dwr0	328	9	on	on	IN
cord-010570-ytv7dwr0	328	10	the	the	DT
cord-010570-ytv7dwr0	328	11	phagocytic	phagocytic	JJ
cord-010570-ytv7dwr0	328	12	activity	activity	NN
cord-010570-ytv7dwr0	328	13	of	of	IN
cord-010570-ytv7dwr0	328	14	leukocytes	leukocyte	NNS
cord-010570-ytv7dwr0	328	15	and	and	CC
cord-010570-ytv7dwr0	328	16	on	on	IN
cord-010570-ytv7dwr0	328	17	the	the	DT
cord-010570-ytv7dwr0	328	18	dissociation	dissociation	NN
cord-010570-ytv7dwr0	328	19	of	of	IN
cord-010570-ytv7dwr0	328	20	streptococci	streptococcus	NNS
cord-010570-ytv7dwr0	328	21	Failure	failure	NN
cord-010570-ytv7dwr0	328	22	of	of	IN
cord-010570-ytv7dwr0	328	23	sulfanilamide	sulfanilamide	NN
cord-010570-ytv7dwr0	328	24	to	to	TO
cord-010570-ytv7dwr0	328	25	inactivate	inactivate	VB
cord-010570-ytv7dwr0	328	26	preformed	preformed	JJ
cord-010570-ytv7dwr0	328	27	hemotoxins	hemotoxin	NNS
cord-010570-ytv7dwr0	328	28	,	,	,
cord-010570-ytv7dwr0	328	29	diphtheric	diphtheric	JJ
cord-010570-ytv7dwr0	328	30	toxin	toxin	NN
cord-010570-ytv7dwr0	328	31	,	,	,
cord-010570-ytv7dwr0	328	32	or	or	CC
cord-010570-ytv7dwr0	328	33	tetanal	tetanal	JJ
cord-010570-ytv7dwr0	328	34	toxin	toxin	NN
cord-010570-ytv7dwr0	328	35	Sulfanilamide	Sulfanilamide	NNP
cord-010570-ytv7dwr0	328	36	and	and	CC
cord-010570-ytv7dwr0	328	37	serum	serum	NN
cord-010570-ytv7dwr0	328	38	in	in	IN
cord-010570-ytv7dwr0	328	39	the	the	DT
cord-010570-ytv7dwr0	328	40	treatment	treatment	NN
cord-010570-ytv7dwr0	328	41	and	and	CC
cord-010570-ytv7dwr0	328	42	prophylaxis	prophylaxis	NN
cord-010570-ytv7dwr0	328	43	of	of	IN
cord-010570-ytv7dwr0	328	44	scarlet	scarlet	JJ
cord-010570-ytv7dwr0	328	45	fever	fever	NN
cord-010570-ytv7dwr0	328	46	Specific	Specific	NNP
cord-010570-ytv7dwr0	328	47	serotherapy	serotherapy	NN
cord-010570-ytv7dwr0	328	48	and	and	CC
cord-010570-ytv7dwr0	328	49	chemotherapy	chemotherapy	NN
cord-010570-ytv7dwr0	328	50	of	of	IN
cord-010570-ytv7dwr0	328	51	the	the	DT
cord-010570-ytv7dwr0	328	52	pneumococcus	pneumococcus	NNP
cord-010570-ytv7dwr0	328	53	pneumonias	pneumonia	NNS
cord-010570-ytv7dwr0	328	54	Treatment	Treatment	NNP
cord-010570-ytv7dwr0	328	55	of	of	IN
cord-010570-ytv7dwr0	328	56	pneumococci	pneumococci	NNP
cord-010570-ytv7dwr0	328	57	meningitis	meningitis	NN
cord-010570-ytv7dwr0	328	58	:	:	:
cord-010570-ytv7dwr0	328	59	a	a	DT
cord-010570-ytv7dwr0	328	60	study	study	NN
cord-010570-ytv7dwr0	328	61	of	of	IN
cord-010570-ytv7dwr0	328	62	ten	ten	CD
cord-010570-ytv7dwr0	328	63	cases	case	NNS
cord-010570-ytv7dwr0	328	64	treated	treat	VBN
cord-010570-ytv7dwr0	328	65	with	with	IN
cord-010570-ytv7dwr0	328	66	sulfanilamide	sulfanilamide	NN
cord-010570-ytv7dwr0	328	67	alone	alone	RB
cord-010570-ytv7dwr0	328	68	or	or	CC
cord-010570-ytv7dwr0	328	69	in	in	IN
cord-010570-ytv7dwr0	328	70	various	various	JJ
cord-010570-ytv7dwr0	328	71	combinations	combination	NNS
cord-010570-ytv7dwr0	328	72	with	with	IN
cord-010570-ytv7dwr0	328	73	antipneumococcic	antipneumococcic	JJ
cord-010570-ytv7dwr0	328	74	serum	serum	NN
cord-010570-ytv7dwr0	328	75	and	and	CC
cord-010570-ytv7dwr0	328	76	complement	complement	NN
cord-010570-ytv7dwr0	328	77	,	,	,
cord-010570-ytv7dwr0	328	78	including	include	VBG
cord-010570-ytv7dwr0	328	79	six	six	CD
cord-010570-ytv7dwr0	328	80	recoveries	recovery	NNS
cord-010570-ytv7dwr0	329	1	The	the	DT
cord-010570-ytv7dwr0	329	2	treatment	treatment	NN
cord-010570-ytv7dwr0	329	3	of	of	IN
cord-010570-ytv7dwr0	329	4	meningococcic	meningococcic	NN
cord-010570-ytv7dwr0	329	5	meningitis	meningitis	NNP
cord-010570-ytv7dwr0	329	6	with	with	IN
cord-010570-ytv7dwr0	329	7	sulfanilamide	sulfanilamide	NNP
cord-010570-ytv7dwr0	329	8	:	:	:
cord-010570-ytv7dwr0	329	9	preliminary	preliminary	JJ
cord-010570-ytv7dwr0	329	10	report	report	NN
cord-010570-ytv7dwr0	329	11	Serum	Serum	NNP
cord-010570-ytv7dwr0	329	12	and	and	CC
cord-010570-ytv7dwr0	329	13	sulphanilamide	sulphanilamide	NN
cord-010570-ytv7dwr0	329	14	in	in	IN
cord-010570-ytv7dwr0	329	15	acute	acute	JJ
cord-010570-ytv7dwr0	329	16	meningococcal	meningococcal	JJ
cord-010570-ytv7dwr0	329	17	meningitis	meningitis	NN
cord-010570-ytv7dwr0	329	18	:	:	:
cord-010570-ytv7dwr0	329	19	a	a	DT
cord-010570-ytv7dwr0	329	20	preliminary	preliminary	JJ
cord-010570-ytv7dwr0	329	21	survey	survey	NN
cord-010570-ytv7dwr0	329	22	based	base	VBN
cord-010570-ytv7dwr0	329	23	on	on	IN
cord-010570-ytv7dwr0	329	24	113	113	CD
cord-010570-ytv7dwr0	329	25	cases	case	NNS
cord-010570-ytv7dwr0	330	1	Intravenous	intravenous	JJ
cord-010570-ytv7dwr0	330	2	usage	usage	NN
cord-010570-ytv7dwr0	330	3	of	of	IN
cord-010570-ytv7dwr0	330	4	gammaglobulin	gammaglobulin	NN
cord-010570-ytv7dwr0	330	5	:	:	:
cord-010570-ytv7dwr0	330	6	humoral	humoral	JJ
cord-010570-ytv7dwr0	330	7	immunodeficiency	immunodeficiency	NN
cord-010570-ytv7dwr0	330	8	,	,	,
cord-010570-ytv7dwr0	330	9	immune	immune	JJ
cord-010570-ytv7dwr0	330	10	thrombocytopenic	thrombocytopenic	JJ
cord-010570-ytv7dwr0	330	11	purpura	purpura	NN
cord-010570-ytv7dwr0	330	12	,	,	,
cord-010570-ytv7dwr0	330	13	and	and	CC
cord-010570-ytv7dwr0	330	14	newer	new	JJR
cord-010570-ytv7dwr0	330	15	indications	indication	NNS
cord-010570-ytv7dwr0	331	1	Intravenous	intravenous	JJ
cord-010570-ytv7dwr0	331	2	immunoglobulins	immunoglobulin	NNS
cord-010570-ytv7dwr0	331	3	as	as	IN
cord-010570-ytv7dwr0	331	4	therapeutic	therapeutic	JJ
cord-010570-ytv7dwr0	331	5	agents	agent	NNS
cord-010570-ytv7dwr0	331	6	Newer	new	JJR
cord-010570-ytv7dwr0	331	7	uses	use	NNS
cord-010570-ytv7dwr0	331	8	of	of	IN
cord-010570-ytv7dwr0	331	9	intravenous	intravenous	JJ
cord-010570-ytv7dwr0	331	10	immunoglobulins	immunoglobulin	NNS
cord-010570-ytv7dwr0	331	11	as	as	IN
cord-010570-ytv7dwr0	331	12	antiinfective	antiinfective	JJ
cord-010570-ytv7dwr0	331	13	agents	agent	NNS
cord-010570-ytv7dwr0	331	14	Prevention	Prevention	NNP
cord-010570-ytv7dwr0	331	15	of	of	IN
cord-010570-ytv7dwr0	331	16	infection	infection	NN
cord-010570-ytv7dwr0	331	17	in	in	IN
cord-010570-ytv7dwr0	331	18	patients	patient	NNS
cord-010570-ytv7dwr0	331	19	with	with	IN
cord-010570-ytv7dwr0	331	20	B	b	NN
cord-010570-ytv7dwr0	331	21	cell	cell	NN
cord-010570-ytv7dwr0	331	22	defects	defect	NNS
cord-010570-ytv7dwr0	331	23	:	:	:
cord-010570-ytv7dwr0	331	24	focus	focus	VB
cord-010570-ytv7dwr0	331	25	on	on	IN
cord-010570-ytv7dwr0	331	26	intravenous	intravenous	JJ
cord-010570-ytv7dwr0	331	27	immunoglobulin	immunoglobulin	NN
cord-010570-ytv7dwr0	331	28	Poisonous	poisonous	JJ
cord-010570-ytv7dwr0	331	29	snakebite	snakebite	NN
cord-010570-ytv7dwr0	331	30	treatment	treatment	NN
cord-010570-ytv7dwr0	331	31	in	in	IN
cord-010570-ytv7dwr0	331	32	the	the	DT
cord-010570-ytv7dwr0	331	33	United	United	NNP
cord-010570-ytv7dwr0	331	34	States	States	NNP
cord-010570-ytv7dwr0	331	35	Medical	Medical	NNP
cord-010570-ytv7dwr0	331	36	toxicologist	toxicologist	NN
cord-010570-ytv7dwr0	331	37	's	's	POS
cord-010570-ytv7dwr0	331	38	notebook	notebook	NN
cord-010570-ytv7dwr0	331	39	:	:	:
cord-010570-ytv7dwr0	331	40	snakebite	snakebite	NN
cord-010570-ytv7dwr0	331	41	treatment	treatment	NN
cord-010570-ytv7dwr0	331	42	and	and	CC
cord-010570-ytv7dwr0	331	43	international	international	JJ
cord-010570-ytv7dwr0	331	44	antivenin	antivenin	NN
cord-010570-ytv7dwr0	331	45	index	index	NN
cord-010570-ytv7dwr0	331	46	Prophylaxis	Prophylaxis	NNP
cord-010570-ytv7dwr0	331	47	of	of	IN
cord-010570-ytv7dwr0	331	48	primary	primary	JJ
cord-010570-ytv7dwr0	331	49	cytomegalovirus	cytomegalovirus	NN
cord-010570-ytv7dwr0	331	50	disease	disease	NN
cord-010570-ytv7dwr0	331	51	in	in	IN
cord-010570-ytv7dwr0	331	52	renal	renal	JJ
cord-010570-ytv7dwr0	331	53	transplant	transplant	NN
cord-010570-ytv7dwr0	331	54	recipients	recipient	NNS
cord-010570-ytv7dwr0	331	55	:	:	:
cord-010570-ytv7dwr0	331	56	a	a	DT
cord-010570-ytv7dwr0	331	57	trial	trial	NN
cord-010570-ytv7dwr0	331	58	of	of	IN
cord-010570-ytv7dwr0	331	59	ganciclovir	ganciclovir	FW
cord-010570-ytv7dwr0	331	60	vs.	vs.	IN
cord-010570-ytv7dwr0	331	61	immunoglobulin	immunoglobulin	NN
cord-010570-ytv7dwr0	331	62	Treatment	Treatment	NNP
cord-010570-ytv7dwr0	331	63	of	of	IN
cord-010570-ytv7dwr0	331	64	cytomegalovirus	cytomegalovirus	JJ
cord-010570-ytv7dwr0	331	65	pneumonia	pneumonia	NN
cord-010570-ytv7dwr0	331	66	with	with	IN
cord-010570-ytv7dwr0	331	67	ganciclovir	ganciclovir	NNP
cord-010570-ytv7dwr0	331	68	and	and	CC
cord-010570-ytv7dwr0	331	69	intravenous	intravenous	JJ
cord-010570-ytv7dwr0	331	70	cytomegalovirus	cytomegalovirus	NN
cord-010570-ytv7dwr0	331	71	immunoglobulin	immunoglobulin	NN
cord-010570-ytv7dwr0	331	72	in	in	IN
cord-010570-ytv7dwr0	331	73	patients	patient	NNS
cord-010570-ytv7dwr0	331	74	with	with	IN
cord-010570-ytv7dwr0	331	75	bone	bone	NN
cord-010570-ytv7dwr0	331	76	marrow	marrow	NN
cord-010570-ytv7dwr0	331	77	transplants	transplant	NNS
cord-010570-ytv7dwr0	332	1	A	a	DT
cord-010570-ytv7dwr0	332	2	randomised	randomised	JJ
cord-010570-ytv7dwr0	332	3	trial	trial	NN
cord-010570-ytv7dwr0	332	4	of	of	IN
cord-010570-ytv7dwr0	332	5	oral	oral	JJ
cord-010570-ytv7dwr0	332	6	gammaglobulin	gammaglobulin	NN
cord-010570-ytv7dwr0	332	7	in	in	IN
cord-010570-ytv7dwr0	332	8	low	low	JJ
cord-010570-ytv7dwr0	332	9	-	-	HYPH
cord-010570-ytv7dwr0	332	10	birth	birth	NN
cord-010570-ytv7dwr0	332	11	-	-	HYPH
cord-010570-ytv7dwr0	332	12	weight	weight	NN
cord-010570-ytv7dwr0	332	13	infants	infant	NNS
cord-010570-ytv7dwr0	332	14	infected	infect	VBN
cord-010570-ytv7dwr0	332	15	with	with	IN
cord-010570-ytv7dwr0	332	16	rotavirus	rotavirus	JJ
cord-010570-ytv7dwr0	332	17	Lassa	Lassa	NNP
cord-010570-ytv7dwr0	332	18	immune	immune	JJ
cord-010570-ytv7dwr0	332	19	serum	serum	NN
cord-010570-ytv7dwr0	332	20	Prevention	prevention	NN
cord-010570-ytv7dwr0	332	21	of	of	IN
cord-010570-ytv7dwr0	332	22	varicella	varicella	NN
cord-010570-ytv7dwr0	332	23	in	in	IN
cord-010570-ytv7dwr0	332	24	high	high	JJ
cord-010570-ytv7dwr0	332	25	risk	risk	NN
cord-010570-ytv7dwr0	332	26	children	child	NNS
cord-010570-ytv7dwr0	332	27	:	:	:
cord-010570-ytv7dwr0	332	28	a	a	DT
cord-010570-ytv7dwr0	332	29	collaborative	collaborative	JJ
cord-010570-ytv7dwr0	332	30	study	study	NN
cord-010570-ytv7dwr0	332	31	Persistent	persistent	JJ
cord-010570-ytv7dwr0	332	32	and	and	CC
cord-010570-ytv7dwr0	332	33	fatal	fatal	JJ
cord-010570-ytv7dwr0	332	34	central	central	JJ
cord-010570-ytv7dwr0	332	35	-	-	HYPH
cord-010570-ytv7dwr0	332	36	nervous	nervous	JJ
cord-010570-ytv7dwr0	332	37	system	system	NN
cord-010570-ytv7dwr0	332	38	echovirus	echovirus	NN
cord-010570-ytv7dwr0	332	39	infections	infection	NNS
cord-010570-ytv7dwr0	332	40	in	in	IN
cord-010570-ytv7dwr0	332	41	patients	patient	NNS
cord-010570-ytv7dwr0	332	42	with	with	IN
cord-010570-ytv7dwr0	332	43	agammaglobulinemia	agammaglobulinemia	NN
cord-010570-ytv7dwr0	332	44	Chronic	Chronic	NNP
cord-010570-ytv7dwr0	332	45	ECHO	ECHO	NNP
cord-010570-ytv7dwr0	332	46	type	type	NN
cord-010570-ytv7dwr0	332	47	5	5	CD
cord-010570-ytv7dwr0	332	48	virus	virus	NN
cord-010570-ytv7dwr0	332	49	meningoencephalitis	meningoencephalitis	NN
cord-010570-ytv7dwr0	332	50	in	in	IN
cord-010570-ytv7dwr0	332	51	X	x	NN
cord-010570-ytv7dwr0	332	52	-	-	HYPH
cord-010570-ytv7dwr0	332	53	linked	link	VBN
cord-010570-ytv7dwr0	332	54	hypogammaglobulinemia	hypogammaglobulinemia	NN
cord-010570-ytv7dwr0	332	55	:	:	:
cord-010570-ytv7dwr0	332	56	treatment	treatment	NN
cord-010570-ytv7dwr0	332	57	with	with	IN
cord-010570-ytv7dwr0	332	58	immune	immune	JJ
cord-010570-ytv7dwr0	332	59	plasma	plasma	NN
cord-010570-ytv7dwr0	333	1	Persistent	persistent	JJ
cord-010570-ytv7dwr0	333	2	B19	B19	NNP
cord-010570-ytv7dwr0	333	3	parvovirus	parvovirus	NN
cord-010570-ytv7dwr0	333	4	infection	infection	NN
cord-010570-ytv7dwr0	333	5	in	in	IN
cord-010570-ytv7dwr0	333	6	patients	patient	NNS
cord-010570-ytv7dwr0	333	7	infected	infect	VBN
cord-010570-ytv7dwr0	333	8	with	with	IN
cord-010570-ytv7dwr0	333	9	human	human	JJ
cord-010570-ytv7dwr0	333	10	immunodeficiency	immunodeficiency	NN
cord-010570-ytv7dwr0	333	11	virus	virus	NN
cord-010570-ytv7dwr0	333	12	type	type	NN
cord-010570-ytv7dwr0	333	13	1	1	CD
cord-010570-ytv7dwr0	333	14	(	(	-LRB-
cord-010570-ytv7dwr0	333	15	HIV	HIV	NNP
cord-010570-ytv7dwr0	333	16	-	-	HYPH
cord-010570-ytv7dwr0	333	17	l	l	NNP
cord-010570-ytv7dwr0	333	18	)	)	-RRB-
cord-010570-ytv7dwr0	333	19	:	:	:
cord-010570-ytv7dwr0	333	20	a	a	DT
cord-010570-ytv7dwr0	333	21	treatable	treatable	JJ
cord-010570-ytv7dwr0	333	22	cause	cause	NN
cord-010570-ytv7dwr0	333	23	of	of	IN
cord-010570-ytv7dwr0	333	24	anemia	anemia	NN
cord-010570-ytv7dwr0	333	25	in	in	IN
cord-010570-ytv7dwr0	333	26	AIDS	AIDS	NNP
cord-010570-ytv7dwr0	333	27	Crossover	Crossover	NNP
cord-010570-ytv7dwr0	333	28	of	of	IN
cord-010570-ytv7dwr0	333	29	placebo	placebo	NN
cord-010570-ytv7dwr0	333	30	patients	patient	NNS
cord-010570-ytv7dwr0	333	31	to	to	IN
cord-010570-ytv7dwr0	333	32	intravenous	intravenous	JJ
cord-010570-ytv7dwr0	333	33	immunoglobulin	immunoglobulin	NN
cord-010570-ytv7dwr0	333	34	confirms	confirm	VBZ
cord-010570-ytv7dwr0	333	35	em	-PRON-	PRP
cord-010570-ytv7dwr0	333	36	1995;21	1995;21	NNP
cord-010570-ytv7dwr0	333	37	(	(	-LRB-
cord-010570-ytv7dwr0	333	38	July	July	NNP
cord-010570-ytv7dwr0	333	39	)	)	-RRB-
cord-010570-ytv7dwr0	333	40	efficacy	efficacy	NN
cord-010570-ytv7dwr0	333	41	for	for	IN
cord-010570-ytv7dwr0	333	42	prophylaxis	prophylaxis	NN
cord-010570-ytv7dwr0	333	43	of	of	IN
cord-010570-ytv7dwr0	333	44	bacterial	bacterial	JJ
cord-010570-ytv7dwr0	333	45	infections	infection	NNS
cord-010570-ytv7dwr0	333	46	and	and	CC
cord-010570-ytv7dwr0	333	47	reduction	reduction	NN
cord-010570-ytv7dwr0	333	48	of	of	IN
cord-010570-ytv7dwr0	333	49	hospitalizations	hospitalization	NNS
cord-010570-ytv7dwr0	333	50	in	in	IN
cord-010570-ytv7dwr0	333	51	human	human	JJ
cord-010570-ytv7dwr0	333	52	immunodeficiency	immunodeficiency	NN
cord-010570-ytv7dwr0	333	53	virus	virus	NN
cord-010570-ytv7dwr0	333	54	-	-	HYPH
cord-010570-ytv7dwr0	333	55	infected	infect	VBN
cord-010570-ytv7dwr0	333	56	children	child	NNS
cord-010570-ytv7dwr0	334	1	Does	do	VBZ
cord-010570-ytv7dwr0	334	2	intravenous	intravenous	JJ
cord-010570-ytv7dwr0	334	3	immune	immune	JJ
cord-010570-ytv7dwr0	334	4	globulin	globulin	NN
cord-010570-ytv7dwr0	334	5	have	have	VBP
cord-010570-ytv7dwr0	334	6	a	a	DT
cord-010570-ytv7dwr0	334	7	role	role	NN
cord-010570-ytv7dwr0	334	8	in	in	IN
cord-010570-ytv7dwr0	334	9	HIV	HIV	NNP
cord-010570-ytv7dwr0	334	10	-	-	HYPH
cord-010570-ytv7dwr0	334	11	infected	infect	VBN
cord-010570-ytv7dwr0	334	12	patients	patient	NNS
cord-010570-ytv7dwr0	334	13	?	?	.
cord-010570-ytv7dwr0	335	1	The	the	DT
cord-010570-ytv7dwr0	335	2	National	National	NNP
cord-010570-ytv7dwr0	335	3	Institute	Institute	NNP
cord-010570-ytv7dwr0	335	4	of	of	IN
cord-010570-ytv7dwr0	335	5	Child	Child	NNP
cord-010570-ytv7dwr0	335	6	Health	Health	NNP
cord-010570-ytv7dwr0	335	7	and	and	CC
cord-010570-ytv7dwr0	335	8	Human	Human	NNP
cord-010570-ytv7dwr0	335	9	Development	Development	NNP
cord-010570-ytv7dwr0	335	10	Intravenous	Intravenous	NNP
cord-010570-ytv7dwr0	335	11	Immunoglobulin	Immunoglobulin	NNP
cord-010570-ytv7dwr0	335	12	Study	Study	NNP
cord-010570-ytv7dwr0	335	13	Group	Group	NNP
cord-010570-ytv7dwr0	335	14	.	.	.
cord-010570-ytv7dwr0	336	1	Intravenous	intravenous	JJ
cord-010570-ytv7dwr0	336	2	immune	immune	JJ
cord-010570-ytv7dwr0	336	3	globulin	globulin	NN
cord-010570-ytv7dwr0	336	4	for	for	IN
cord-010570-ytv7dwr0	336	5	the	the	DT
cord-010570-ytv7dwr0	336	6	prevention	prevention	NN
cord-010570-ytv7dwr0	336	7	of	of	IN
cord-010570-ytv7dwr0	336	8	bacterial	bacterial	JJ
cord-010570-ytv7dwr0	336	9	infections	infection	NNS
cord-010570-ytv7dwr0	336	10	in	in	IN
cord-010570-ytv7dwr0	336	11	children	child	NNS
cord-010570-ytv7dwr0	336	12	with	with	IN
cord-010570-ytv7dwr0	336	13	symptomatic	symptomatic	JJ
cord-010570-ytv7dwr0	336	14	human	human	JJ
cord-010570-ytv7dwr0	336	15	immunodeficiency	immunodeficiency	NN
cord-010570-ytv7dwr0	336	16	virus	virus	NN
cord-010570-ytv7dwr0	336	17	infection	infection	NN
cord-010570-ytv7dwr0	336	18	Prophylactic	Prophylactic	NNP
cord-010570-ytv7dwr0	336	19	intravenous	intravenous	JJ
cord-010570-ytv7dwr0	336	20	administration	administration	NN
cord-010570-ytv7dwr0	336	21	of	of	IN
cord-010570-ytv7dwr0	336	22	standard	standard	JJ
cord-010570-ytv7dwr0	336	23	immune	immune	JJ
cord-010570-ytv7dwr0	336	24	globulin	globulin	NN
cord-010570-ytv7dwr0	337	1	as	as	IN
cord-010570-ytv7dwr0	337	2	compared	compare	VBN
cord-010570-ytv7dwr0	337	3	with	with	IN
cord-010570-ytv7dwr0	337	4	core	core	NN
cord-010570-ytv7dwr0	337	5	-	-	HYPH
cord-010570-ytv7dwr0	337	6	lipopolysaccharide	lipopolysaccharide	NN
cord-010570-ytv7dwr0	337	7	immune	immune	JJ
cord-010570-ytv7dwr0	337	8	globulin	globulin	NN
cord-010570-ytv7dwr0	337	9	in	in	IN
cord-010570-ytv7dwr0	337	10	patients	patient	NNS
cord-010570-ytv7dwr0	337	11	at	at	IN
cord-010570-ytv7dwr0	337	12	high	high	JJ
cord-010570-ytv7dwr0	337	13	risk	risk	NN
cord-010570-ytv7dwr0	337	14	of	of	IN
cord-010570-ytv7dwr0	337	15	postsurgical	postsurgical	JJ
cord-010570-ytv7dwr0	337	16	infection	infection	NN
cord-010570-ytv7dwr0	338	1	A	a	DT
cord-010570-ytv7dwr0	338	2	randomized	randomized	JJ
cord-010570-ytv7dwr0	338	3	prospective	prospective	JJ
cord-010570-ytv7dwr0	338	4	trial	trial	NN
cord-010570-ytv7dwr0	338	5	of	of	IN
cord-010570-ytv7dwr0	338	6	acyclovir	acyclovir	NNP
cord-010570-ytv7dwr0	338	7	and	and	CC
cord-010570-ytv7dwr0	338	8	immune	immune	JJ
cord-010570-ytv7dwr0	338	9	globulin	globulin	NN
cord-010570-ytv7dwr0	338	10	prophylaxis	prophylaxis	NN
cord-010570-ytv7dwr0	338	11	in	in	IN
cord-010570-ytv7dwr0	338	12	liver	liver	NN
cord-010570-ytv7dwr0	338	13	transplant	transplant	NN
cord-010570-ytv7dwr0	338	14	recipients	recipient	NNS
cord-010570-ytv7dwr0	338	15	receiving	receive	VBG
cord-010570-ytv7dwr0	338	16	OKT3	OKT3	NNP
cord-010570-ytv7dwr0	338	17	therapy	therapy	NN
cord-010570-ytv7dwr0	338	18	Intravenous	Intravenous	NNP
cord-010570-ytv7dwr0	338	19	gammaglobulin	gammaglobulin	NN
cord-010570-ytv7dwr0	338	20	therapy	therapy	NN
cord-010570-ytv7dwr0	338	21	for	for	IN
cord-010570-ytv7dwr0	338	22	prophylaxis	prophylaxis	NN
cord-010570-ytv7dwr0	338	23	of	of	IN
cord-010570-ytv7dwr0	338	24	infection	infection	NN
cord-010570-ytv7dwr0	338	25	in	in	IN
cord-010570-ytv7dwr0	338	26	high	high	JJ
cord-010570-ytv7dwr0	338	27	-	-	HYPH
cord-010570-ytv7dwr0	338	28	risk	risk	NN
cord-010570-ytv7dwr0	338	29	neonates	neonate	NNS
cord-010570-ytv7dwr0	338	30	Multicenter	Multicenter	NNP
cord-010570-ytv7dwr0	338	31	Group	Group	NNP
cord-010570-ytv7dwr0	338	32	for	for	IN
cord-010570-ytv7dwr0	338	33	the	the	DT
cord-010570-ytv7dwr0	338	34	Study	Study	NNP
cord-010570-ytv7dwr0	338	35	of	of	IN
cord-010570-ytv7dwr0	338	36	Immune	Immune	NNP
cord-010570-ytv7dwr0	338	37	Globulin	Globulin	NNP
cord-010570-ytv7dwr0	338	38	in	in	IN
cord-010570-ytv7dwr0	338	39	Neonates	Neonates	NNPS
cord-010570-ytv7dwr0	338	40	.	.	.
cord-010570-ytv7dwr0	339	1	Intravenous	intravenous	JJ
cord-010570-ytv7dwr0	339	2	immune	immune	JJ
cord-010570-ytv7dwr0	339	3	globulin	globulin	NN
cord-010570-ytv7dwr0	339	4	for	for	IN
cord-010570-ytv7dwr0	339	5	the	the	DT
cord-010570-ytv7dwr0	339	6	prevention	prevention	NN
cord-010570-ytv7dwr0	339	7	of	of	IN
cord-010570-ytv7dwr0	339	8	nosocomial	nosocomial	JJ
cord-010570-ytv7dwr0	339	9	infection	infection	NN
cord-010570-ytv7dwr0	339	10	in	in	IN
cord-010570-ytv7dwr0	339	11	low	low	JJ
cord-010570-ytv7dwr0	339	12	-	-	HYPH
cord-010570-ytv7dwr0	339	13	birth	birth	NN
cord-010570-ytv7dwr0	339	14	-	-	HYPH
cord-010570-ytv7dwr0	339	15	weight	weight	NN
cord-010570-ytv7dwr0	339	16	neonates	neonate	NNS
cord-010570-ytv7dwr0	340	1	Intravenous	intravenous	JJ
cord-010570-ytv7dwr0	340	2	immunoglobulin	immunoglobulin	NN
cord-010570-ytv7dwr0	340	3	use	use	NN
cord-010570-ytv7dwr0	340	4	in	in	IN
cord-010570-ytv7dwr0	340	5	the	the	DT
cord-010570-ytv7dwr0	340	6	neonate	neonate	NN
cord-010570-ytv7dwr0	340	7	:	:	:
cord-010570-ytv7dwr0	340	8	role	role	NN
cord-010570-ytv7dwr0	340	9	in	in	IN
cord-010570-ytv7dwr0	340	10	prophylaxis	prophylaxis	NN
cord-010570-ytv7dwr0	340	11	and	and	CC
cord-010570-ytv7dwr0	340	12	therapy	therapy	NN
cord-010570-ytv7dwr0	340	13	of	of	IN
cord-010570-ytv7dwr0	340	14	infection	infection	NN
cord-010570-ytv7dwr0	340	15	Use	Use	NNP
cord-010570-ytv7dwr0	340	16	of	of	IN
cord-010570-ytv7dwr0	340	17	immunoglobulins	immunoglobulin	NNS
cord-010570-ytv7dwr0	340	18	in	in	IN
cord-010570-ytv7dwr0	340	19	prevention	prevention	NN
cord-010570-ytv7dwr0	340	20	and	and	CC
cord-010570-ytv7dwr0	340	21	treatment	treatment	NN
cord-010570-ytv7dwr0	340	22	of	of	IN
cord-010570-ytv7dwr0	340	23	infection	infection	NN
cord-010570-ytv7dwr0	340	24	in	in	IN
cord-010570-ytv7dwr0	340	25	critically	critically	RB
cord-010570-ytv7dwr0	340	26	ill	ill	JJ
cord-010570-ytv7dwr0	340	27	patients	patient	NNS
cord-010570-ytv7dwr0	340	28	:	:	:
cord-010570-ytv7dwr0	340	29	review	review	VB
cord-010570-ytv7dwr0	340	30	and	and	CC
cord-010570-ytv7dwr0	340	31	critique	critique	VB
cord-010570-ytv7dwr0	340	32	New	New	NNP
cord-010570-ytv7dwr0	340	33	uses	use	NNS
cord-010570-ytv7dwr0	340	34	for	for	IN
cord-010570-ytv7dwr0	340	35	intravenous	intravenous	JJ
cord-010570-ytv7dwr0	340	36	immune	immune	JJ
cord-010570-ytv7dwr0	340	37	globulin	globulin	NN
cord-010570-ytv7dwr0	340	38	Immune	Immune	NNP
cord-010570-ytv7dwr0	340	39	globulin	globulin	NN
cord-010570-ytv7dwr0	340	40	to	to	TO
cord-010570-ytv7dwr0	340	41	prevent	prevent	VB
cord-010570-ytv7dwr0	340	42	nosocomial	nosocomial	JJ
cord-010570-ytv7dwr0	340	43	infections	infection	NNS
cord-010570-ytv7dwr0	340	44	Rhesus	Rhesus	NNP
cord-010570-ytv7dwr0	340	45	haemolytic	haemolytic	JJ
cord-010570-ytv7dwr0	340	46	disease	disease	NN
cord-010570-ytv7dwr0	341	1	The	the	DT
cord-010570-ytv7dwr0	341	2	clinical	clinical	JJ
cord-010570-ytv7dwr0	341	3	value	value	NN
cord-010570-ytv7dwr0	341	4	of	of	IN
cord-010570-ytv7dwr0	341	5	antilymphocyte	antilymphocyte	NNP
cord-010570-ytv7dwr0	341	6	antibodies	antibody	NNS
cord-010570-ytv7dwr0	341	7	Ortho	Ortho	NNP
cord-010570-ytv7dwr0	341	8	Multicenter	Multicenter	NNP
cord-010570-ytv7dwr0	341	9	Transplant	Transplant	NNP
cord-010570-ytv7dwr0	341	10	Study	Study	NNP
cord-010570-ytv7dwr0	341	11	Group	Group	NNP
cord-010570-ytv7dwr0	341	12	.	.	.
cord-010570-ytv7dwr0	342	1	A	a	DT
cord-010570-ytv7dwr0	342	2	randomized	randomized	JJ
cord-010570-ytv7dwr0	342	3	clinical	clinical	JJ
cord-010570-ytv7dwr0	342	4	trial	trial	NN
cord-010570-ytv7dwr0	342	5	of	of	IN
cord-010570-ytv7dwr0	342	6	OKT3	OKT3	NNP
cord-010570-ytv7dwr0	342	7	monoclonal	monoclonal	JJ
cord-010570-ytv7dwr0	342	8	antibody	antibody	NN
cord-010570-ytv7dwr0	342	9	for	for	IN
cord-010570-ytv7dwr0	342	10	acute	acute	JJ
cord-010570-ytv7dwr0	342	11	rejection	rejection	NN
cord-010570-ytv7dwr0	342	12	of	of	IN
cord-010570-ytv7dwr0	342	13	cadaveric	cadaveric	JJ
cord-010570-ytv7dwr0	342	14	renal	renal	JJ
cord-010570-ytv7dwr0	342	15	transplants	transplant	NNS
cord-010570-ytv7dwr0	342	16	Treatment	treatment	NN
cord-010570-ytv7dwr0	342	17	of	of	IN
cord-010570-ytv7dwr0	342	18	life	life	NN
cord-010570-ytv7dwr0	342	19	-	-	HYPH
cord-010570-ytv7dwr0	342	20	threatening	threaten	VBG
cord-010570-ytv7dwr0	342	21	digitalis	digitalis	NN
cord-010570-ytv7dwr0	342	22	intoxication	intoxication	NN
cord-010570-ytv7dwr0	342	23	with	with	IN
cord-010570-ytv7dwr0	342	24	digoxin	digoxin	NN
cord-010570-ytv7dwr0	342	25	-	-	HYPH
cord-010570-ytv7dwr0	342	26	specific	specific	JJ
cord-010570-ytv7dwr0	342	27	Fab	fab	JJ
cord-010570-ytv7dwr0	342	28	antibody	antibody	NN
cord-010570-ytv7dwr0	342	29	fragments	fragment	NNS
cord-010570-ytv7dwr0	342	30	:	:	:
cord-010570-ytv7dwr0	342	31	experience	experience	NN
cord-010570-ytv7dwr0	342	32	in	in	IN
cord-010570-ytv7dwr0	342	33	26	26	CD
cord-010570-ytv7dwr0	342	34	cases	case	NNS
cord-010570-ytv7dwr0	343	1	Opsonic	opsonic	JJ
cord-010570-ytv7dwr0	343	2	activity	activity	NN
cord-010570-ytv7dwr0	343	3	of	of	IN
cord-010570-ytv7dwr0	343	4	commercially	commercially	RB
cord-010570-ytv7dwr0	343	5	available	available	JJ
cord-010570-ytv7dwr0	343	6	standard	standard	JJ
cord-010570-ytv7dwr0	343	7	intravenous	intravenous	JJ
cord-010570-ytv7dwr0	343	8	immunoglobulin	immunoglobulin	NN
cord-010570-ytv7dwr0	343	9	preparations	preparation	NNS
cord-010570-ytv7dwr0	343	10	Human	human	JJ
cord-010570-ytv7dwr0	343	11	immunoglobulins	immunoglobulin	NNS
cord-010570-ytv7dwr0	343	12	for	for	IN
cord-010570-ytv7dwr0	343	13	intravenous	intravenous	JJ
cord-010570-ytv7dwr0	343	14	use	use	NN
cord-010570-ytv7dwr0	343	15	and	and	CC
cord-010570-ytv7dwr0	343	16	hepatitis	hepatitis	NN
cord-010570-ytv7dwr0	343	17	C	c	NN
cord-010570-ytv7dwr0	343	18	viral	viral	JJ
cord-010570-ytv7dwr0	343	19	transmission	transmission	NN
cord-010570-ytv7dwr0	343	20	Continuous	continuous	JJ
cord-010570-ytv7dwr0	343	21	cultures	culture	NNS
cord-010570-ytv7dwr0	343	22	of	of	IN
cord-010570-ytv7dwr0	343	23	fused	fuse	VBN
cord-010570-ytv7dwr0	343	24	cells	cell	NNS
cord-010570-ytv7dwr0	343	25	secreting	secrete	VBG
cord-010570-ytv7dwr0	343	26	antibody	antibody	NN
cord-010570-ytv7dwr0	343	27	of	of	IN
cord-010570-ytv7dwr0	343	28	predefined	predefined	JJ
cord-010570-ytv7dwr0	343	29	specificity	specificity	NN
cord-010570-ytv7dwr0	343	30	Genetically	genetically	RB
cord-010570-ytv7dwr0	343	31	engineered	engineer	VBN
cord-010570-ytv7dwr0	343	32	antibodies	antibody	NNS
cord-010570-ytv7dwr0	343	33	:	:	:
cord-010570-ytv7dwr0	343	34	progress	progress	NN
cord-010570-ytv7dwr0	343	35	and	and	CC
cord-010570-ytv7dwr0	343	36	prospects	prospect	NNS
cord-010570-ytv7dwr0	343	37	Mouse	Mouse	NNP
cord-010570-ytv7dwr0	343	38	/	/	SYM
cord-010570-ytv7dwr0	343	39	human	human	JJ
cord-010570-ytv7dwr0	343	40	chimeric	chimeric	JJ
cord-010570-ytv7dwr0	343	41	monoclonal	monoclonal	JJ
cord-010570-ytv7dwr0	343	42	antibody	antibody	NN
cord-010570-ytv7dwr0	343	43	in	in	IN
cord-010570-ytv7dwr0	343	44	man	man	NN
cord-010570-ytv7dwr0	343	45	:	:	:
cord-010570-ytv7dwr0	343	46	kinetics	kinetics	NN
cord-010570-ytv7dwr0	343	47	and	and	CC
cord-010570-ytv7dwr0	343	48	immune	immune	JJ
cord-010570-ytv7dwr0	343	49	response	response	NN
cord-010570-ytv7dwr0	343	50	Anti	anti	JJ
cord-010570-ytv7dwr0	343	51	-	-	JJ
cord-010570-ytv7dwr0	343	52	endotoxin	endotoxin	JJ
cord-010570-ytv7dwr0	343	53	monoclonal	monoclonal	JJ
cord-010570-ytv7dwr0	343	54	antibodies	antibody	NNS
cord-010570-ytv7dwr0	343	55	Introduction	Introduction	NNP
cord-010570-ytv7dwr0	343	56	of	of	IN
cord-010570-ytv7dwr0	343	57	new	new	JJ
cord-010570-ytv7dwr0	343	58	technology	technology	NN
cord-010570-ytv7dwr0	343	59	into	into	IN
cord-010570-ytv7dwr0	343	60	critical	critical	JJ
cord-010570-ytv7dwr0	343	61	care	care	NN
cord-010570-ytv7dwr0	343	62	practice	practice	NN
cord-010570-ytv7dwr0	343	63	:	:	:
cord-010570-ytv7dwr0	343	64	a	a	DT
cord-010570-ytv7dwr0	343	65	history	history	NN
cord-010570-ytv7dwr0	343	66	ofHA	ofHA	NNP
cord-010570-ytv7dwr0	343	67	-	-	HYPH
cord-010570-ytv7dwr0	343	68	lA	lA	NNP
cord-010570-ytv7dwr0	343	69	human	human	JJ
cord-010570-ytv7dwr0	343	70	monoclonal	monoclonal	JJ
cord-010570-ytv7dwr0	343	71	antibody	antibody	NN
cord-010570-ytv7dwr0	343	72	against	against	IN
cord-010570-ytv7dwr0	343	73	endotoxin	endotoxin	NN
cord-010570-ytv7dwr0	343	74	Versuche	Versuche	NNP
cord-010570-ytv7dwr0	343	75	tiber	tiber	NNP
cord-010570-ytv7dwr0	343	76	immunisirung	immunisirung	NNP
cord-010570-ytv7dwr0	344	1	und	und	IN
cord-010570-ytv7dwr0	344	2	heilung	heilung	NNP
cord-010570-ytv7dwr0	344	3	bei	bei	NNP
cord-010570-ytv7dwr0	344	4	der	der	NNP
cord-010570-ytv7dwr0	345	1	pneumokokkeninfektion	pneumokokkeninfektion	NNP
cord-010570-ytv7dwr0	345	2	A	a	DT
cord-010570-ytv7dwr0	345	3	biologic	biologic	JJ
cord-010570-ytv7dwr0	345	4	classification	classification	NN
cord-010570-ytv7dwr0	345	5	of	of	IN
cord-010570-ytv7dwr0	345	6	pneumococci	pneumococci	NNP
cord-010570-ytv7dwr0	345	7	by	by	IN
cord-010570-ytv7dwr0	345	8	means	mean	NNS
cord-010570-ytv7dwr0	345	9	of	of	IN
cord-010570-ytv7dwr0	345	10	immunity	immunity	NN
cord-010570-ytv7dwr0	345	11	reactions	reaction	NNS
cord-010570-ytv7dwr0	346	1	Weitere	Weitere	NNP
cord-010570-ytv7dwr0	346	2	Untersuchungen	Untersuchungen	NNP
cord-010570-ytv7dwr0	346	3	uber	uber	NNP
cord-010570-ytv7dwr0	346	4	Pneumokokken	Pneumokokken	NNP
cord-010570-ytv7dwr0	346	5	-	-	HYPH
cord-010570-ytv7dwr0	346	6	Heilsera	Heilsera	NNP
cord-010570-ytv7dwr0	346	7	.	.	.
cord-010570-ytv7dwr0	347	1	Arb	Arb	NNP
cord-010570-ytv7dwr0	347	2	a	a	DT
cord-010570-ytv7dwr0	347	3	d	d	NN
cord-010570-ytv7dwr0	347	4	k	k	NN
cord-010570-ytv7dwr0	348	1	The	the	DT
cord-010570-ytv7dwr0	348	2	reliability	reliability	NN
cord-010570-ytv7dwr0	348	3	of	of	IN
cord-010570-ytv7dwr0	348	4	sputum	sputum	NN
cord-010570-ytv7dwr0	348	5	typing	typing	NN
cord-010570-ytv7dwr0	348	6	and	and	CC
cord-010570-ytv7dwr0	348	7	its	-PRON-	PRP$
cord-010570-ytv7dwr0	348	8	relation	relation	NN
cord-010570-ytv7dwr0	348	9	to	to	IN
cord-010570-ytv7dwr0	348	10	serum	serum	NN
cord-010570-ytv7dwr0	348	11	therapy	therapy	NN
cord-010570-ytv7dwr0	349	1	The	the	DT
cord-010570-ytv7dwr0	349	2	meningococcus	meningococcus	NN
cord-010570-ytv7dwr0	349	3	(	(	-LRB-
cord-010570-ytv7dwr0	349	4	Neisseria	Neisseria	NNP
cord-010570-ytv7dwr0	349	5	intracellularis	intracellularis	NNP
cord-010570-ytv7dwr0	349	6	)	)	-RRB-
cord-010570-ytv7dwr0	349	7	Serums	serum	NNS
cord-010570-ytv7dwr0	349	8	,	,	,
cord-010570-ytv7dwr0	349	9	antitoxin	antitoxin	NN
cord-010570-ytv7dwr0	349	10	,	,	,
cord-010570-ytv7dwr0	349	11	and	and	CC
cord-010570-ytv7dwr0	349	12	drugs	drug	NNS
cord-010570-ytv7dwr0	349	13	in	in	IN
cord-010570-ytv7dwr0	349	14	the	the	DT
cord-010570-ytv7dwr0	349	15	treatment	treatment	NN
cord-010570-ytv7dwr0	349	16	of	of	IN
cord-010570-ytv7dwr0	349	17	meningococcus	meningococcus	NNP
cord-010570-ytv7dwr0	349	18	meningitis	meningitis	NN
cord-010570-ytv7dwr0	350	1	The	the	DT
cord-010570-ytv7dwr0	350	2	management	management	NN
cord-010570-ytv7dwr0	350	3	of	of	IN
cord-010570-ytv7dwr0	350	4	the	the	DT
cord-010570-ytv7dwr0	350	5	pneumonias	pneumonia	NNS
cord-010570-ytv7dwr0	350	6	Principles	Principles	NNPS
cord-010570-ytv7dwr0	350	7	and	and	CC
cord-010570-ytv7dwr0	350	8	practice	practice	NN
cord-010570-ytv7dwr0	350	9	of	of	IN
cord-010570-ytv7dwr0	350	10	infectious	infectious	JJ
cord-010570-ytv7dwr0	350	11	diseases	disease	NNS
cord-010570-ytv7dwr0	350	12	Therapeutic	therapeutic	JJ
cord-010570-ytv7dwr0	350	13	effects	effect	NNS
cord-010570-ytv7dwr0	350	14	of	of	IN
cord-010570-ytv7dwr0	350	15	a	a	DT
cord-010570-ytv7dwr0	350	16	human	human	JJ
cord-010570-ytv7dwr0	350	17	antiflagella	antiflagella	NN
cord-010570-ytv7dwr0	350	18	monoclonal	monoclonal	JJ
cord-010570-ytv7dwr0	350	19	antibody	antibody	NN
cord-010570-ytv7dwr0	350	20	in	in	IN
cord-010570-ytv7dwr0	350	21	a	a	DT
cord-010570-ytv7dwr0	350	22	neutropenic	neutropenic	JJ
cord-010570-ytv7dwr0	350	23	murine	murine	JJ
cord-010570-ytv7dwr0	350	24	model	model	NN
cord-010570-ytv7dwr0	350	25	of	of	IN
cord-010570-ytv7dwr0	350	26	Pseudomonas	Pseudomonas	NNP
cord-010570-ytv7dwr0	350	27	aeruginosa	aeruginosa	NN
cord-010570-ytv7dwr0	350	28	pneumonia	pneumonia	NN
cord-010570-ytv7dwr0	350	29	Immune	immune	JJ
cord-010570-ytv7dwr0	350	30	enhancement	enhancement	NN
cord-010570-ytv7dwr0	350	31	of	of	IN
cord-010570-ytv7dwr0	350	32	viral	viral	JJ
cord-010570-ytv7dwr0	350	33	infection	infection	NN
cord-010570-ytv7dwr0	350	34	Metabolism	metabolism	NN
cord-010570-ytv7dwr0	350	35	of	of	IN
cord-010570-ytv7dwr0	350	36	immunoglobulins	immunoglobulin	NNS
cord-010570-ytv7dwr0	350	37	Immunologic	immunologic	JJ
cord-010570-ytv7dwr0	350	38	and	and	CC
cord-010570-ytv7dwr0	350	39	pharmacologic	pharmacologic	JJ
cord-010570-ytv7dwr0	350	40	concepts	concept	NNS
cord-010570-ytv7dwr0	350	41	of	of	IN
cord-010570-ytv7dwr0	350	42	monoclonal	monoclonal	JJ
cord-010570-ytv7dwr0	350	43	antibodies	antibody	NNS
cord-010570-ytv7dwr0	350	44	Placental	placental	JJ
cord-010570-ytv7dwr0	350	45	transfer	transfer	NN
cord-010570-ytv7dwr0	350	46	of	of	IN
cord-010570-ytv7dwr0	350	47	human	human	JJ
cord-010570-ytv7dwr0	350	48	IgG	igg	NN
cord-010570-ytv7dwr0	350	49	subclasses	subclass	NNS
cord-010570-ytv7dwr0	350	50	Treatment	Treatment	NNP
cord-010570-ytv7dwr0	350	51	of	of	IN
cord-010570-ytv7dwr0	350	52	chronic	chronic	JJ
cord-010570-ytv7dwr0	350	53	cryptosporidial	cryptosporidial	NN
cord-010570-ytv7dwr0	350	54	infection	infection	NN
cord-010570-ytv7dwr0	350	55	with	with	IN
cord-010570-ytv7dwr0	350	56	orally	orally	RB
cord-010570-ytv7dwr0	350	57	administered	administer	VBN
cord-010570-ytv7dwr0	350	58	human	human	JJ
cord-010570-ytv7dwr0	350	59	serum	serum	NN
cord-010570-ytv7dwr0	350	60	immune	immune	NN
cord-010570-ytv7dwr0	350	61	globulin	globulin	NN
cord-010570-ytv7dwr0	350	62	Intravenous	Intravenous	NNP
cord-010570-ytv7dwr0	350	63	treatment	treatment	NN
cord-010570-ytv7dwr0	350	64	of	of	IN
cord-010570-ytv7dwr0	350	65	meningococcic	meningococcic	NNP
cord-010570-ytv7dwr0	350	66	meningitis	meningitis	NNP
cord-010570-ytv7dwr0	350	67	with	with	IN
cord-010570-ytv7dwr0	350	68	meningococcus	meningococcus	NNP
cord-010570-ytv7dwr0	350	69	antitoxin	antitoxin	NN
cord-010570-ytv7dwr0	350	70	Blood	blood	NN
cord-010570-ytv7dwr0	350	71	-	-	HYPH
cord-010570-ytv7dwr0	350	72	brain	brain	NN
cord-010570-ytv7dwr0	350	73	barrier	barrier	NN
cord-010570-ytv7dwr0	350	74	transport	transport	NN
cord-010570-ytv7dwr0	350	75	of	of	IN
cord-010570-ytv7dwr0	350	76	cationized	cationized	JJ
cord-010570-ytv7dwr0	350	77	immunoglobulin	immunoglobulin	NN
cord-010570-ytv7dwr0	350	78	G	g	NN
cord-010570-ytv7dwr0	350	79	:	:	:
cord-010570-ytv7dwr0	350	80	enhanced	enhance	VBN
cord-010570-ytv7dwr0	350	81	delivery	delivery	NN
cord-010570-ytv7dwr0	350	82	compared	compare	VBN
cord-010570-ytv7dwr0	350	83	to	to	IN
cord-010570-ytv7dwr0	350	84	native	native	JJ
cord-010570-ytv7dwr0	350	85	protein	protein	NN
cord-010570-ytv7dwr0	350	86	Anti	Anti	NNP
cord-010570-ytv7dwr0	350	87	-	-	JJ
cord-010570-ytv7dwr0	350	88	transferrin	transferrin	JJ
cord-010570-ytv7dwr0	350	89	receptor	receptor	NN
cord-010570-ytv7dwr0	350	90	antibody	antibody	NN
cord-010570-ytv7dwr0	350	91	and	and	CC
cord-010570-ytv7dwr0	350	92	antibody	antibody	NN
cord-010570-ytv7dwr0	350	93	-	-	HYPH
cord-010570-ytv7dwr0	350	94	drug	drug	NN
cord-010570-ytv7dwr0	350	95	conjugates	conjugate	NNS
cord-010570-ytv7dwr0	350	96	cross	cross	VBP
cord-010570-ytv7dwr0	350	97	the	the	DT
cord-010570-ytv7dwr0	350	98	blood	blood	NN
cord-010570-ytv7dwr0	350	99	-	-	HYPH
cord-010570-ytv7dwr0	350	100	brain	brain	NN
cord-010570-ytv7dwr0	350	101	barrier	barrier	NN
cord-010570-ytv7dwr0	350	102	Acute	acute	JJ
cord-010570-ytv7dwr0	350	103	renal	renal	JJ
cord-010570-ytv7dwr0	350	104	failure	failure	NN
cord-010570-ytv7dwr0	350	105	after	after	IN
cord-010570-ytv7dwr0	350	106	intravenous	intravenous	JJ
cord-010570-ytv7dwr0	350	107	immunoglobulin	immunoglobulin	NN
cord-010570-ytv7dwr0	350	108	therapy	therapy	NN
cord-010570-ytv7dwr0	350	109	Aseptic	aseptic	JJ
cord-010570-ytv7dwr0	350	110	meningitis	meningitis	NN
cord-010570-ytv7dwr0	350	111	associated	associate	VBN
cord-010570-ytv7dwr0	350	112	with	with	IN
cord-010570-ytv7dwr0	350	113	high	high	JJ
cord-010570-ytv7dwr0	350	114	-	-	HYPH
cord-010570-ytv7dwr0	350	115	dose	dose	NN
cord-010570-ytv7dwr0	350	116	intravenous	intravenous	JJ
cord-010570-ytv7dwr0	350	117	immunoglobulin	immunoglobulin	NN
cord-010570-ytv7dwr0	350	118	therapy	therapy	NN
cord-010570-ytv7dwr0	350	119	:	:	:
cord-010570-ytv7dwr0	350	120	frequency	frequency	NN
cord-010570-ytv7dwr0	350	121	and	and	CC
cord-010570-ytv7dwr0	350	122	risk	risk	NN
cord-010570-ytv7dwr0	350	123	factors	factor	NNS
cord-010570-ytv7dwr0	350	124	High	high	JJ
cord-010570-ytv7dwr0	350	125	-	-	HYPH
cord-010570-ytv7dwr0	350	126	dose	dose	NN
cord-010570-ytv7dwr0	350	127	weekly	weekly	JJ
cord-010570-ytv7dwr0	350	128	intravenous	intravenous	JJ
cord-010570-ytv7dwr0	350	129	immunoglobulin	immunoglobulin	NN
cord-010570-ytv7dwr0	350	130	to	to	TO
cord-010570-ytv7dwr0	350	131	prevent	prevent	VB
cord-010570-ytv7dwr0	350	132	infections	infection	NNS
cord-010570-ytv7dwr0	350	133	in	in	IN
cord-010570-ytv7dwr0	350	134	patients	patient	NNS
cord-010570-ytv7dwr0	350	135	undergoing	undergo	VBG
cord-010570-ytv7dwr0	350	136	autologous	autologous	JJ
cord-010570-ytv7dwr0	350	137	bone	bone	NN
cord-010570-ytv7dwr0	350	138	marrow	marrow	NN
cord-010570-ytv7dwr0	350	139	transplantation	transplantation	NN
cord-010570-ytv7dwr0	350	140	or	or	CC
cord-010570-ytv7dwr0	350	141	severe	severe	JJ
cord-010570-ytv7dwr0	350	142	myelosuppressive	myelosuppressive	NNP
cord-010570-ytv7dwr0	350	143	therapy	therapy	NN
cord-010570-ytv7dwr0	350	144	:	:	:
cord-010570-ytv7dwr0	350	145	a	a	DT
cord-010570-ytv7dwr0	350	146	study	study	NN
cord-010570-ytv7dwr0	350	147	of	of	IN
cord-010570-ytv7dwr0	350	148	the	the	DT
cord-010570-ytv7dwr0	350	149	American	American	NNP
cord-010570-ytv7dwr0	350	150	Bone	Bone	NNP
cord-010570-ytv7dwr0	350	151	Marrow	Marrow	NNP
cord-010570-ytv7dwr0	350	152	Transplant	Transplant	NNP
cord-010570-ytv7dwr0	350	153	Group	Group	NNP
cord-010570-ytv7dwr0	350	154	High	High	NNP
cord-010570-ytv7dwr0	350	155	-	-	HYPH
cord-010570-ytv7dwr0	350	156	dose	dose	NN
cord-010570-ytv7dwr0	350	157	intravenous	intravenous	JJ
cord-010570-ytv7dwr0	350	158	immunoglobulin	immunoglobulin	NN
cord-010570-ytv7dwr0	350	159	and	and	CC
cord-010570-ytv7dwr0	350	160	serum	serum	NN
cord-010570-ytv7dwr0	350	161	viscosity	viscosity	NN
cord-010570-ytv7dwr0	350	162	:	:	:
cord-010570-ytv7dwr0	350	163	risk	risk	NN
cord-010570-ytv7dwr0	350	164	of	of	IN
cord-010570-ytv7dwr0	350	165	precipitating	precipitate	VBG
cord-010570-ytv7dwr0	350	166	thromboembolic	thromboembolic	JJ
cord-010570-ytv7dwr0	350	167	events	event	NNS
cord-010570-ytv7dwr0	350	168	Immunotherapy	Immunotherapy	NNP
cord-010570-ytv7dwr0	350	169	with	with	IN
cord-010570-ytv7dwr0	350	170	human	human	JJ
cord-010570-ytv7dwr0	350	171	monoclonal	monoclonal	JJ
cord-010570-ytv7dwr0	350	172	antibodies	antibody	NNS
cord-010570-ytv7dwr0	350	173	:	:	:
cord-010570-ytv7dwr0	351	1	fragment	fragment	VB
cord-010570-ytv7dwr0	351	2	A	a	DT
cord-010570-ytv7dwr0	351	3	specificity	specificity	NN
cord-010570-ytv7dwr0	351	4	of	of	IN
cord-010570-ytv7dwr0	351	5	polyclonal	polyclonal	JJ
cord-010570-ytv7dwr0	351	6	and	and	CC
cord-010570-ytv7dwr0	351	7	monoclonal	monoclonal	JJ
cord-010570-ytv7dwr0	351	8	antibodies	antibody	NNS
cord-010570-ytv7dwr0	351	9	is	be	VBZ
cord-010570-ytv7dwr0	351	10	crucial	crucial	JJ
cord-010570-ytv7dwr0	351	11	for	for	IN
cord-010570-ytv7dwr0	351	12	full	full	JJ
cord-010570-ytv7dwr0	351	13	protection	protection	NN
cord-010570-ytv7dwr0	351	14	against	against	IN
cord-010570-ytv7dwr0	351	15	tetanus	tetanus	NN
cord-010570-ytv7dwr0	351	16	toxin	toxin	NN
cord-010570-ytv7dwr0	352	1	A	a	DT
cord-010570-ytv7dwr0	352	2	controlled	control	VBN
cord-010570-ytv7dwr0	352	3	clinical	clinical	JJ
cord-010570-ytv7dwr0	352	4	trial	trial	NN
cord-010570-ytv7dwr0	352	5	of	of	IN
cord-010570-ytv7dwr0	352	6	E5	E5	NNP
cord-010570-ytv7dwr0	352	7	murine	murine	JJ
cord-010570-ytv7dwr0	352	8	monoclonal	monoclonal	JJ
cord-010570-ytv7dwr0	352	9	IgM	IgM	NNP
cord-010570-ytv7dwr0	352	10	antibody	antibody	NN
cord-010570-ytv7dwr0	352	11	to	to	TO
cord-010570-ytv7dwr0	352	12	endotoxin	endotoxin	VB
cord-010570-ytv7dwr0	352	13	in	in	IN
cord-010570-ytv7dwr0	352	14	the	the	DT
cord-010570-ytv7dwr0	352	15	treatment	treatment	NN
cord-010570-ytv7dwr0	352	16	of	of	IN
cord-010570-ytv7dwr0	352	17	gram	gram	NN
cord-010570-ytv7dwr0	352	18	-	-	HYPH
cord-010570-ytv7dwr0	352	19	negative	negative	JJ
cord-010570-ytv7dwr0	352	20	sepsis	sepsis	NN
cord-010570-ytv7dwr0	353	1	Human	human	JJ
cord-010570-ytv7dwr0	353	2	anti	anti	JJ
cord-010570-ytv7dwr0	353	3	-	-	JJ
cord-010570-ytv7dwr0	353	4	murine	murine	JJ
cord-010570-ytv7dwr0	353	5	immunoglobulin	immunoglobulin	NN
cord-010570-ytv7dwr0	353	6	responses	response	NNS
cord-010570-ytv7dwr0	353	7	in	in	IN
cord-010570-ytv7dwr0	353	8	patients	patient	NNS
cord-010570-ytv7dwr0	353	9	receiving	receive	VBG
cord-010570-ytv7dwr0	353	10	monoclonal	monoclonal	JJ
cord-010570-ytv7dwr0	353	11	antibody	antibody	NN
cord-010570-ytv7dwr0	353	12	therapy	therapy	NN
cord-010570-ytv7dwr0	353	13	Chimeric	Chimeric	NNP
cord-010570-ytv7dwr0	353	14	CD4	CD4	NNP
cord-010570-ytv7dwr0	353	15	monoclonal	monoclonal	JJ
cord-010570-ytv7dwr0	353	16	antibody	antibody	NN
cord-010570-ytv7dwr0	353	17	cM	cM	NNP
cord-010570-ytv7dwr0	353	18	-	-	:
cord-010570-ytv7dwr0	353	19	T412	T412	NNP
cord-010570-ytv7dwr0	353	20	as	as	IN
cord-010570-ytv7dwr0	353	21	a	a	DT
cord-010570-ytv7dwr0	353	22	therapeutic	therapeutic	JJ
cord-010570-ytv7dwr0	353	23	approach	approach	NN
cord-010570-ytv7dwr0	353	24	to	to	IN
cord-010570-ytv7dwr0	353	25	rheumatoid	rheumatoid	NNP
cord-010570-ytv7dwr0	353	26	arthritis	arthritis	NN
cord-010570-ytv7dwr0	353	27	Human	Human	NNP
cord-010570-ytv7dwr0	353	28	mouse	mouse	NN
cord-010570-ytv7dwr0	353	29	chimeric	chimeric	JJ
cord-010570-ytv7dwr0	353	30	CD7	CD7	NNP
cord-010570-ytv7dwr0	353	31	monoclonal	monoclonal	JJ
cord-010570-ytv7dwr0	353	32	antibody	antibody	NN
cord-010570-ytv7dwr0	353	33	(	(	-LRB-
cord-010570-ytv7dwr0	353	34	SDZCHH380	SDZCHH380	NNP
cord-010570-ytv7dwr0	353	35	)	)	-RRB-
cord-010570-ytv7dwr0	353	36	for	for	IN
cord-010570-ytv7dwr0	353	37	the	the	DT
cord-010570-ytv7dwr0	353	38	prophylaxis	prophylaxis	NN
cord-010570-ytv7dwr0	353	39	of	of	IN
cord-010570-ytv7dwr0	353	40	kidney	kidney	NN
cord-010570-ytv7dwr0	353	41	transplant	transplant	NN
cord-010570-ytv7dwr0	353	42	rejection	rejection	NN
cord-010570-ytv7dwr0	353	43	Humanised	Humanised	NNP
cord-010570-ytv7dwr0	353	44	monoclonal	monoclonal	JJ
cord-010570-ytv7dwr0	353	45	antibody	antibody	NN
cord-010570-ytv7dwr0	353	46	therapy	therapy	NN
cord-010570-ytv7dwr0	353	47	for	for	IN
cord-010570-ytv7dwr0	353	48	rheumatoid	rheumatoid	NNP
cord-010570-ytv7dwr0	353	49	arthritis	arthritis	NN
cord-010570-ytv7dwr0	353	50	Remission	Remission	NNP
cord-010570-ytv7dwr0	353	51	induction	induction	NN
cord-010570-ytv7dwr0	353	52	in	in	IN
cord-010570-ytv7dwr0	353	53	non	non	JJ
cord-010570-ytv7dwr0	353	54	-	-	JJ
cord-010570-ytv7dwr0	353	55	Hodgkin	hodgkin	JJ
cord-010570-ytv7dwr0	353	56	lymphoma	lymphoma	NN
cord-010570-ytv7dwr0	353	57	with	with	IN
cord-010570-ytv7dwr0	353	58	reshaped	reshape	VBN
cord-010570-ytv7dwr0	353	59	human	human	JJ
cord-010570-ytv7dwr0	353	60	monoclonal	monoclonal	JJ
cord-010570-ytv7dwr0	353	61	antibody	antibody	NN
cord-010570-ytv7dwr0	353	62	CAMPATH	CAMPATH	NNP
cord-010570-ytv7dwr0	353	63	-	-	HYPH
cord-010570-ytv7dwr0	353	64	lH	lH	NNP
cord-010570-ytv7dwr0	353	65	Antibody	antibody	NN
cord-010570-ytv7dwr0	353	66	-	-	HYPH
cord-010570-ytv7dwr0	353	67	resistant	resistant	JJ
cord-010570-ytv7dwr0	353	68	mutants	mutant	NNS
cord-010570-ytv7dwr0	353	69	of	of	IN
cord-010570-ytv7dwr0	353	70	Borrelia	Borrelia	NNP
cord-010570-ytv7dwr0	353	71	burgdorferi	burgdorferi	NN
cord-010570-ytv7dwr0	353	72	:	:	:
cord-010570-ytv7dwr0	353	73	in	in	IN
cord-010570-ytv7dwr0	353	74	vitro	vitro	FW
cord-010570-ytv7dwr0	353	75	selection	selection	NN
cord-010570-ytv7dwr0	353	76	and	and	CC
cord-010570-ytv7dwr0	353	77	characterization	characterization	NN
cord-010570-ytv7dwr0	353	78	Mosaic	Mosaic	NNP
cord-010570-ytv7dwr0	353	79	-	-	HYPH
cord-010570-ytv7dwr0	353	80	like	like	JJ
cord-010570-ytv7dwr0	353	81	organization	organization	NN
cord-010570-ytv7dwr0	353	82	ofIgA	ofIgA	NNS
cord-010570-ytv7dwr0	353	83	protease	protease	NN
cord-010570-ytv7dwr0	353	84	genes	gene	NNS
cord-010570-ytv7dwr0	353	85	in	in	IN
cord-010570-ytv7dwr0	353	86	Neisseria	Neisseria	NNP
cord-010570-ytv7dwr0	353	87	gonorrhoeae	gonorrhoeae	NNP
cord-010570-ytv7dwr0	353	88	generated	generate	VBN
cord-010570-ytv7dwr0	353	89	by	by	IN
cord-010570-ytv7dwr0	353	90	horizontal	horizontal	JJ
cord-010570-ytv7dwr0	353	91	genetic	genetic	JJ
cord-010570-ytv7dwr0	353	92	exchange	exchange	NN
cord-010570-ytv7dwr0	353	93	in	in	IN
cord-010570-ytv7dwr0	353	94	vivo	vivo	NNP
cord-010570-ytv7dwr0	353	95	Cost	cost	NN
cord-010570-ytv7dwr0	353	96	effectiveness	effectiveness	NN
cord-010570-ytv7dwr0	353	97	of	of	IN
cord-010570-ytv7dwr0	353	98	prophylactic	prophylactic	JJ
cord-010570-ytv7dwr0	353	99	intravenous	intravenous	JJ
cord-010570-ytv7dwr0	353	100	immune	immune	JJ
cord-010570-ytv7dwr0	353	101	globulin	globulin	NN
cord-010570-ytv7dwr0	353	102	in	in	IN
cord-010570-ytv7dwr0	353	103	chronic	chronic	JJ
cord-010570-ytv7dwr0	353	104	lymphocytic	lymphocytic	JJ
cord-010570-ytv7dwr0	353	105	leukemia	leukemia	NN
cord-010570-ytv7dwr0	353	106	Passive	passive	JJ
cord-010570-ytv7dwr0	353	107	immunization	immunization	NN
cord-010570-ytv7dwr0	353	108	in	in	IN
cord-010570-ytv7dwr0	353	109	murine	murine	JJ
cord-010570-ytv7dwr0	353	110	cryptococcosis	cryptococcosis	NN
cord-010570-ytv7dwr0	353	111	Passive	passive	JJ
cord-010570-ytv7dwr0	353	112	immunization	immunization	NN
cord-010570-ytv7dwr0	353	113	against	against	IN
cord-010570-ytv7dwr0	353	114	Cryptococcus	Cryptococcus	NNP
cord-010570-ytv7dwr0	353	115	neoformans	neoforman	VBZ
cord-010570-ytv7dwr0	353	116	Protection	Protection	NNP
cord-010570-ytv7dwr0	353	117	of	of	IN
cord-010570-ytv7dwr0	353	118	mice	mouse	NNS
cord-010570-ytv7dwr0	353	119	against	against	IN
cord-010570-ytv7dwr0	353	120	experimental	experimental	JJ
cord-010570-ytv7dwr0	353	121	cryptococcosis	cryptococcosis	NN
cord-010570-ytv7dwr0	353	122	by	by	IN
cord-010570-ytv7dwr0	353	123	anti	anti	NNP
cord-010570-ytv7dwr0	353	124	-	-	NNP
cord-010570-ytv7dwr0	353	125	Cryptococcus	Cryptococcus	NNP
cord-010570-ytv7dwr0	353	126	neoformans	neoforman	VBZ
cord-010570-ytv7dwr0	353	127	monoclonal	monoclonal	JJ
cord-010570-ytv7dwr0	353	128	antibody	antibody	NN
cord-010570-ytv7dwr0	353	129	Passive	passive	JJ
cord-010570-ytv7dwr0	353	130	immunization	immunization	NN
cord-010570-ytv7dwr0	353	131	against	against	IN
cord-010570-ytv7dwr0	353	132	Cryptococcus	Cryptococcus	NNP
cord-010570-ytv7dwr0	353	133	neoformans	neoforman	NNS
cord-010570-ytv7dwr0	353	134	with	with	IN
cord-010570-ytv7dwr0	353	135	an	an	DT
cord-010570-ytv7dwr0	353	136	isotype	isotype	NN
cord-010570-ytv7dwr0	353	137	-	-	HYPH
cord-010570-ytv7dwr0	353	138	switch	switch	NN
cord-010570-ytv7dwr0	353	139	family	family	NN
cord-010570-ytv7dwr0	353	140	of	of	IN
cord-010570-ytv7dwr0	353	141	monoclonal	monoclonal	JJ
cord-010570-ytv7dwr0	353	142	antibodies	antibody	NNS
cord-010570-ytv7dwr0	353	143	reactive	reactive	JJ
cord-010570-ytv7dwr0	353	144	with	with	IN
cord-010570-ytv7dwr0	353	145	cryptococcal	cryptococcal	JJ
cord-010570-ytv7dwr0	353	146	polysaccharide	polysaccharide	NN
cord-010570-ytv7dwr0	353	147	Protective	protective	JJ
cord-010570-ytv7dwr0	353	148	murine	murine	JJ
cord-010570-ytv7dwr0	353	149	monoclonal	monoclonal	JJ
cord-010570-ytv7dwr0	353	150	antibodies	antibody	NNS
cord-010570-ytv7dwr0	353	151	to	to	IN
cord-010570-ytv7dwr0	353	152	Cryptococcus	Cryptococcus	NNP
cord-010570-ytv7dwr0	353	153	neoformans	neoforman	VBZ
cord-010570-ytv7dwr0	353	154	Serum	serum	NN
cord-010570-ytv7dwr0	353	155	protein	protein	NN
cord-010570-ytv7dwr0	353	156	enhancement	enhancement	NN
cord-010570-ytv7dwr0	353	157	of	of	IN
cord-010570-ytv7dwr0	353	158	antibiotic	antibiotic	JJ
cord-010570-ytv7dwr0	353	159	therapy	therapy	NN
cord-010570-ytv7dwr0	353	160	in	in	IN
cord-010570-ytv7dwr0	353	161	cryptococcosis	cryptococcosis	NN
cord-010570-ytv7dwr0	353	162	Improved	improve	VBD
cord-010570-ytv7dwr0	353	163	amphotericin	amphotericin	NNS
cord-010570-ytv7dwr0	353	164	B	b	NN
cord-010570-ytv7dwr0	353	165	activity	activity	NN
cord-010570-ytv7dwr0	353	166	by	by	IN
cord-010570-ytv7dwr0	353	167	a	a	DT
cord-010570-ytv7dwr0	353	168	monoclonal	monoclonal	JJ
cord-010570-ytv7dwr0	353	169	anti	anti	JJ
cord-010570-ytv7dwr0	353	170	-	-	NNP
cord-010570-ytv7dwr0	353	171	Cryptococcus	Cryptococcus	NNP
cord-010570-ytv7dwr0	353	172	neoformans	neoforman	VBZ
cord-010570-ytv7dwr0	353	173	antibody	antibody	NN
cord-010570-ytv7dwr0	353	174	:	:	:
cord-010570-ytv7dwr0	353	175	study	study	VB
cord-010570-ytv7dwr0	353	176	during	during	IN
cord-010570-ytv7dwr0	353	177	murine	murine	JJ
cord-010570-ytv7dwr0	353	178	cryptococco	cryptococco	NNP
cord-010570-ytv7dwr0	353	179	sis	sis	NN
cord-010570-ytv7dwr0	353	180	and	and	CC
cord-010570-ytv7dwr0	353	181	mechanisms	mechanism	NNS
cord-010570-ytv7dwr0	353	182	of	of	IN
cord-010570-ytv7dwr0	353	183	action	action	NN
cord-010570-ytv7dwr0	353	184	Therapeutic	therapeutic	JJ
cord-010570-ytv7dwr0	353	185	efficacy	efficacy	NN
cord-010570-ytv7dwr0	353	186	of	of	IN
cord-010570-ytv7dwr0	353	187	monoclonal	monoclonal	JJ
cord-010570-ytv7dwr0	353	188	antibodies	antibody	NNS
cord-010570-ytv7dwr0	353	189	to	to	IN
cord-010570-ytv7dwr0	353	190	Cryptococcus	Cryptococcus	NNP
cord-010570-ytv7dwr0	353	191	neoformans	neoforman	VBZ
cord-010570-ytv7dwr0	353	192	glueuronoxylomannan	glueuronoxylomannan	NNP
cord-010570-ytv7dwr0	353	193	alone	alone	JJ
cord-010570-ytv7dwr0	353	194	and	and	CC
cord-010570-ytv7dwr0	353	195	in	in	IN
cord-010570-ytv7dwr0	353	196	combination	combination	NN
cord-010570-ytv7dwr0	353	197	with	with	IN
cord-010570-ytv7dwr0	353	198	Amphotericin	Amphotericin	NNP
cord-010570-ytv7dwr0	353	199	B	B	NNP
cord-010570-ytv7dwr0	353	200	Isotype	Isotype	NNP
cord-010570-ytv7dwr0	353	201	switching	switch	VBG
cord-010570-ytv7dwr0	353	202	from	from	IN
cord-010570-ytv7dwr0	353	203	IgG3	IgG3	NNP
cord-010570-ytv7dwr0	353	204	to	to	IN
cord-010570-ytv7dwr0	353	205	IgG	IgG	NNP
cord-010570-ytv7dwr0	353	206	1	1	CD
cord-010570-ytv7dwr0	353	207	converts	convert	VBZ
cord-010570-ytv7dwr0	353	208	a	a	DT
cord-010570-ytv7dwr0	353	209	non	non	JJ
cord-010570-ytv7dwr0	353	210	-	-	JJ
cord-010570-ytv7dwr0	353	211	protective	protective	JJ
cord-010570-ytv7dwr0	353	212	murine	murine	JJ
cord-010570-ytv7dwr0	353	213	antibody	antibody	NN
cord-010570-ytv7dwr0	353	214	to	to	IN
cord-010570-ytv7dwr0	353	215	C.	C.	NNP
cord-010570-ytv7dwr0	353	216	neoformans	neoformans	NNP
cord-010570-ytv7dwr0	353	217	into	into	IN
cord-010570-ytv7dwr0	353	218	a	a	DT
cord-010570-ytv7dwr0	353	219	protective	protective	JJ
cord-010570-ytv7dwr0	353	220	antibody	antibody	NN
cord-010570-ytv7dwr0	353	221	Protective	protective	JJ
cord-010570-ytv7dwr0	353	222	and	and	CC
cord-010570-ytv7dwr0	353	223	nonprotective	nonprotective	JJ
cord-010570-ytv7dwr0	353	224	monoclonal	monoclonal	JJ
cord-010570-ytv7dwr0	353	225	antibodies	antibody	NNS
cord-010570-ytv7dwr0	353	226	to	to	IN
cord-010570-ytv7dwr0	353	227	Cryptococcus	Cryptococcus	NNP
cord-010570-ytv7dwr0	353	228	neoformans	neoforman	NNS
cord-010570-ytv7dwr0	353	229	originating	originate	VBG
cord-010570-ytv7dwr0	353	230	from	from	IN
cord-010570-ytv7dwr0	353	231	one	one	CD
cord-010570-ytv7dwr0	353	232	B	b	NN
cord-010570-ytv7dwr0	353	233	cell	cell	NN
cord-010570-ytv7dwr0	353	234	Toxoplasma	toxoplasma	NN
cord-010570-ytv7dwr0	353	235	gondii	gondii	NN
cord-010570-ytv7dwr0	353	236	:	:	:
cord-010570-ytv7dwr0	353	237	a	a	DT
cord-010570-ytv7dwr0	353	238	monoclonal	monoclonal	JJ
cord-010570-ytv7dwr0	353	239	antibody	antibody	NN
cord-010570-ytv7dwr0	353	240	that	that	WDT
cord-010570-ytv7dwr0	353	241	inhibits	inhibit	VBZ
cord-010570-ytv7dwr0	353	242	intracellular	intracellular	JJ
cord-010570-ytv7dwr0	353	243	replication	replication	NN
cord-010570-ytv7dwr0	354	1	Intracellular	intracellular	JJ
cord-010570-ytv7dwr0	354	2	neutralization	neutralization	NN
cord-010570-ytv7dwr0	354	3	of	of	IN
cord-010570-ytv7dwr0	354	4	virus	virus	NN
cord-010570-ytv7dwr0	354	5	by	by	IN
cord-010570-ytv7dwr0	354	6	immunoglobulin	immunoglobulin	NN
cord-010570-ytv7dwr0	354	7	A	a	DT
cord-010570-ytv7dwr0	354	8	antibodies	antibody	NNS
cord-010570-ytv7dwr0	355	1	A	a	DT
cord-010570-ytv7dwr0	355	2	subgroup	subgroup	NN
cord-010570-ytv7dwr0	355	3	of	of	IN
cord-010570-ytv7dwr0	355	4	murine	murine	JJ
cord-010570-ytv7dwr0	355	5	monoclonal	monoclonal	JJ
cord-010570-ytv7dwr0	355	6	anti	anti	JJ
cord-010570-ytv7dwr0	355	7	-	-	JJ
cord-010570-ytv7dwr0	355	8	deoxyribonucleic	deoxyribonucleic	JJ
cord-010570-ytv7dwr0	355	9	acid	acid	NN
cord-010570-ytv7dwr0	355	10	antibodies	antibody	NNS
cord-010570-ytv7dwr0	355	11	traverse	traverse	VBP
cord-010570-ytv7dwr0	355	12	the	the	DT
cord-010570-ytv7dwr0	355	13	cytoplasm	cytoplasm	NN
cord-010570-ytv7dwr0	355	14	and	and	CC
cord-010570-ytv7dwr0	355	15	enter	enter	VB
cord-010570-ytv7dwr0	355	16	the	the	DT
cord-010570-ytv7dwr0	355	17	nucleus	nucleus	NN
cord-010570-ytv7dwr0	355	18	in	in	IN
cord-010570-ytv7dwr0	355	19	a	a	DT
cord-010570-ytv7dwr0	355	20	time	time	NN
cord-010570-ytv7dwr0	355	21	-	-	HYPH
cord-010570-ytv7dwr0	355	22	and	and	CC
cord-010570-ytv7dwr0	355	23	temperature	temperature	NN
cord-010570-ytv7dwr0	355	24	-	-	HYPH
cord-010570-ytv7dwr0	355	25	dependent	dependent	JJ
cord-010570-ytv7dwr0	355	26	manner	manner	NN
cord-010570-ytv7dwr0	356	1	Passive	passive	JJ
cord-010570-ytv7dwr0	356	2	immunoprophylaxis	immunoprophylaxis	RB
cord-010570-ytv7dwr0	356	3	with	with	IN
cord-010570-ytv7dwr0	356	4	specific	specific	JJ
cord-010570-ytv7dwr0	356	5	monoclonal	monoclonal	JJ
cord-010570-ytv7dwr0	356	6	antibody	antibody	NN
cord-010570-ytv7dwr0	356	7	confers	confer	VBZ
cord-010570-ytv7dwr0	356	8	partial	partial	JJ
cord-010570-ytv7dwr0	356	9	protection	protection	NN
cord-010570-ytv7dwr0	356	10	against	against	IN
cord-010570-ytv7dwr0	356	11	Pneumocystis	Pneumocystis	NNP
cord-010570-ytv7dwr0	356	12	carinii	carinii	FW
cord-010570-ytv7dwr0	356	13	pneumonitis	pneumonitis	NN
cord-010570-ytv7dwr0	356	14	in	in	IN
cord-010570-ytv7dwr0	356	15	animal	animal	NN
cord-010570-ytv7dwr0	356	16	models	model	NNS
cord-010570-ytv7dwr0	357	1	Anti	anti	JJ
cord-010570-ytv7dwr0	357	2	-	-	JJ
cord-010570-ytv7dwr0	357	3	Cryptosporidium	cryptosporidium	JJ
cord-010570-ytv7dwr0	357	4	parvum	parvum	NN
cord-010570-ytv7dwr0	357	5	antibodies	antibody	NNS
cord-010570-ytv7dwr0	357	6	inhibit	inhibit	VBP
cord-010570-ytv7dwr0	357	7	infectivity	infectivity	NN
cord-010570-ytv7dwr0	357	8	in	in	IN
cord-010570-ytv7dwr0	357	9	vitro	vitro	FW
cord-010570-ytv7dwr0	357	10	and	and	CC
cord-010570-ytv7dwr0	357	11	in	in	IN
cord-010570-ytv7dwr0	357	12	vivo	vivo	NNP
cord-010570-ytv7dwr0	357	13	Production	production	NN
cord-010570-ytv7dwr0	357	14	,	,	,
cord-010570-ytv7dwr0	357	15	characterization	characterization	NN
cord-010570-ytv7dwr0	357	16	,	,	,
cord-010570-ytv7dwr0	357	17	and	and	CC
cord-010570-ytv7dwr0	357	18	antibody	antibody	NN
cord-010570-ytv7dwr0	357	19	specificity	specificity	NN
cord-010570-ytv7dwr0	357	20	of	of	IN
cord-010570-ytv7dwr0	357	21	a	a	DT
cord-010570-ytv7dwr0	357	22	mouse	mouse	NN
cord-010570-ytv7dwr0	357	23	monoclonal	monoclonal	JJ
cord-010570-ytv7dwr0	357	24	antibody	antibody	NN
cord-010570-ytv7dwr0	357	25	reactive	reactive	JJ
cord-010570-ytv7dwr0	357	26	with	with	IN
cord-010570-ytv7dwr0	357	27	Cryptococcus	Cryptococcus	NNP
cord-010570-ytv7dwr0	357	28	neoformans	neoforman	VBZ
cord-010570-ytv7dwr0	357	29	capsular	capsular	NN
cord-010570-ytv7dwr0	357	30	polysaccharide	polysaccharide	NN
cord-010570-ytv7dwr0	357	31	Autoantibody	Autoantibody	NNP
cord-010570-ytv7dwr0	357	32	to	to	TO
cord-010570-ytv7dwr0	357	33	heat	heat	VB
cord-010570-ytv7dwr0	357	34	-	-	HYPH
cord-010570-ytv7dwr0	357	35	shock	shock	NN
cord-010570-ytv7dwr0	357	36	protein	protein	NN
cord-010570-ytv7dwr0	357	37	90	90	CD
cord-010570-ytv7dwr0	357	38	can	can	MD
cord-010570-ytv7dwr0	357	39	mediate	mediate	VB
cord-010570-ytv7dwr0	357	40	protection	protection	NN
cord-010570-ytv7dwr0	357	41	against	against	IN
cord-010570-ytv7dwr0	357	42	systemic	systemic	JJ
cord-010570-ytv7dwr0	357	43	candidosis	candidosis	NNP
cord-010570-ytv7dwr0	357	44	Mills	mill	NNS
cord-010570-ytv7dwr0	357	45	1	1	CD
cord-010570-ytv7dwr0	357	46	.	.	.
cord-010570-ytv7dwr0	358	1	Prevention	prevention	NN
cord-010570-ytv7dwr0	358	2	and	and	CC
cord-010570-ytv7dwr0	358	3	treatment	treatment	NN
cord-010570-ytv7dwr0	358	4	of	of	IN
cord-010570-ytv7dwr0	358	5	experimental	experimental	JJ
cord-010570-ytv7dwr0	358	6	herpes	herpes	NN
cord-010570-ytv7dwr0	358	7	simplex	simplex	NN
cord-010570-ytv7dwr0	358	8	virus	virus	NN
cord-010570-ytv7dwr0	358	9	encephalitis	encephalitis	RB
cord-010570-ytv7dwr0	358	10	with	with	IN
cord-010570-ytv7dwr0	358	11	human	human	JJ
cord-010570-ytv7dwr0	358	12	immune	immune	JJ
cord-010570-ytv7dwr0	358	13	serum	serum	NN
cord-010570-ytv7dwr0	358	14	globulin	globulin	NN
cord-010570-ytv7dwr0	358	15	Human	human	JJ
cord-010570-ytv7dwr0	358	16	monoclonal	monoclonal	JJ
cord-010570-ytv7dwr0	358	17	antibodies	antibody	NNS
cord-010570-ytv7dwr0	358	18	neutralizing	neutralize	VBG
cord-010570-ytv7dwr0	358	19	cytomegalovirus	cytomegalovirus	NNP
cord-010570-ytv7dwr0	358	20	(	(	-LRB-
cord-010570-ytv7dwr0	358	21	CMV	CMV	NNP
cord-010570-ytv7dwr0	358	22	)	)	-RRB-
cord-010570-ytv7dwr0	358	23	for	for	IN
cord-010570-ytv7dwr0	358	24	prophylaxis	prophylaxis	NN
cord-010570-ytv7dwr0	358	25	of	of	IN
cord-010570-ytv7dwr0	358	26	CMV	CMV	NNP
cord-010570-ytv7dwr0	358	27	disease	disease	NN
cord-010570-ytv7dwr0	358	28	:	:	:
cord-010570-ytv7dwr0	359	1	report	report	NN
cord-010570-ytv7dwr0	359	2	of	of	IN
cord-010570-ytv7dwr0	359	3	a	a	DT
cord-010570-ytv7dwr0	359	4	phase	phase	NN
cord-010570-ytv7dwr0	359	5	I	-PRON-	PRP
cord-010570-ytv7dwr0	359	6	trial	trial	NN
cord-010570-ytv7dwr0	359	7	in	in	IN
cord-010570-ytv7dwr0	359	8	bone	bone	NN
cord-010570-ytv7dwr0	359	9	marrow	marrow	NN
cord-010570-ytv7dwr0	359	10	transplant	transplant	NN
cord-010570-ytv7dwr0	359	11	recipients	recipient	NNS
cord-010570-ytv7dwr0	359	12	Polyclonal	Polyclonal	NNP
cord-010570-ytv7dwr0	359	13	and	and	CC
cord-010570-ytv7dwr0	359	14	monoclonal	monoclonal	JJ
cord-010570-ytv7dwr0	359	15	antibody	antibody	NN
cord-010570-ytv7dwr0	359	16	therapy	therapy	NN
cord-010570-ytv7dwr0	359	17	for	for	IN
cord-010570-ytv7dwr0	359	18	experimental	experimental	JJ
cord-010570-ytv7dwr0	359	19	Pseudomonas	Pseudomonas	NNP
cord-010570-ytv7dwr0	359	20	aeruginosa	aeruginosa	NN
cord-010570-ytv7dwr0	359	21	pneumonia	pneumonia	NN
cord-010570-ytv7dwr0	359	22	vitro	vitro	FW
cord-010570-ytv7dwr0	359	23	and	and	CC
cord-010570-ytv7dwr0	359	24	in	in	IN
cord-010570-ytv7dwr0	359	25	vivo	vivo	NN
cord-010570-ytv7dwr0	359	26	activity	activity	NN
cord-010570-ytv7dwr0	359	27	of	of	IN
cord-010570-ytv7dwr0	359	28	polyclonal	polyclonal	JJ
cord-010570-ytv7dwr0	359	29	and	and	CC
cord-010570-ytv7dwr0	359	30	monoclonal	monoclonal	JJ
cord-010570-ytv7dwr0	359	31	human	human	JJ
cord-010570-ytv7dwr0	359	32	immunoglobulins	immunoglobulin	NNS
cord-010570-ytv7dwr0	359	33	G	G	NNP
cord-010570-ytv7dwr0	359	34	,	,	,
cord-010570-ytv7dwr0	359	35	M	M	NNP
cord-010570-ytv7dwr0	359	36	,	,	,
cord-010570-ytv7dwr0	359	37	and	and	CC
cord-010570-ytv7dwr0	359	38	A	a	DT
cord-010570-ytv7dwr0	359	39	against	against	IN
cord-010570-ytv7dwr0	359	40	Pseudomonas	Pseudomonas	NNP
cord-010570-ytv7dwr0	359	41	aeruginosa	aeruginosa	NN
cord-010570-ytv7dwr0	359	42	lipopolysaccharide	lipopolysaccharide	NN
cord-010570-ytv7dwr0	359	43	Confronting	confront	VBG
cord-010570-ytv7dwr0	359	44	drug	drug	NN
cord-010570-ytv7dwr0	359	45	-	-	HYPH
cord-010570-ytv7dwr0	359	46	resistant	resistant	JJ
cord-010570-ytv7dwr0	359	47	pneumococci	pneumococci	NN
cord-010570-ytv7dwr0	359	48	Immunoglobulin	Immunoglobulin	NNP
cord-010570-ytv7dwr0	359	49	G	G	NNP
cord-010570-ytv7dwr0	359	50	enhances	enhance	VBZ
cord-010570-ytv7dwr0	359	51	C3	c3	JJ
cord-010570-ytv7dwr0	359	52	degradation	degradation	NN
cord-010570-ytv7dwr0	359	53	on	on	IN
cord-010570-ytv7dwr0	359	54	coagulase	coagulase	NN
cord-010570-ytv7dwr0	359	55	-	-	HYPH
cord-010570-ytv7dwr0	359	56	negative	negative	JJ
cord-010570-ytv7dwr0	359	57	staphylococci	staphylococcus	NNS
cord-010570-ytv7dwr0	360	1	Passive	passive	JJ
cord-010570-ytv7dwr0	360	2	local	local	JJ
cord-010570-ytv7dwr0	360	3	immunotherapy	immunotherapy	NN
cord-010570-ytv7dwr0	360	4	of	of	IN
cord-010570-ytv7dwr0	360	5	experimental	experimental	JJ
cord-010570-ytv7dwr0	360	6	staphylococcal	staphylococcal	JJ
cord-010570-ytv7dwr0	360	7	pneumonia	pneumonia	NN
cord-010570-ytv7dwr0	360	8	with	with	IN
cord-010570-ytv7dwr0	360	9	human	human	JJ
cord-010570-ytv7dwr0	360	10	intravenous	intravenous	JJ
cord-010570-ytv7dwr0	360	11	immunoglobulin	immunoglobulin	NN
cord-010570-ytv7dwr0	360	12	Roles	Roles	NNP
cord-010570-ytv7dwr0	360	13	of	of	IN
cord-010570-ytv7dwr0	360	14	antibodies	antibody	NNS
cord-010570-ytv7dwr0	360	15	and	and	CC
cord-010570-ytv7dwr0	360	16	complement	complement	VB
cord-010570-ytv7dwr0	360	17	in	in	IN
cord-010570-ytv7dwr0	360	18	phagocytic	phagocytic	JJ
cord-010570-ytv7dwr0	360	19	killing	killing	NN
cord-010570-ytv7dwr0	360	20	of	of	IN
cord-010570-ytv7dwr0	360	21	enterococci	enterococci	NNP
cord-010570-ytv7dwr0	360	22	Treatment	Treatment	NNP
cord-010570-ytv7dwr0	360	23	of	of	IN
cord-010570-ytv7dwr0	360	24	gram	gram	JJ
cord-010570-ytv7dwr0	360	25	-	-	HYPH
cord-010570-ytv7dwr0	360	26	negative	negative	JJ
cord-010570-ytv7dwr0	360	27	bacteremia	bacteremia	NN
cord-010570-ytv7dwr0	360	28	and	and	CC
cord-010570-ytv7dwr0	360	29	shock	shock	NN
cord-010570-ytv7dwr0	360	30	with	with	IN
cord-010570-ytv7dwr0	360	31	human	human	JJ
cord-010570-ytv7dwr0	360	32	antiserum	antiserum	NN
cord-010570-ytv7dwr0	360	33	to	to	IN
cord-010570-ytv7dwr0	360	34	a	a	DT
cord-010570-ytv7dwr0	360	35	mutant	mutant	JJ
cord-010570-ytv7dwr0	360	36	Escherichia	Escherichia	NNP
cord-010570-ytv7dwr0	360	37	coli	coli	NNS
cord-010570-ytv7dwr0	360	38	Phase	phase	NN
cord-010570-ytv7dwr0	360	39	I	-PRON-	PRP
cord-010570-ytv7dwr0	360	40	study	study	VBP
cord-010570-ytv7dwr0	360	41	of	of	IN
cord-010570-ytv7dwr0	360	42	a	a	DT
cord-010570-ytv7dwr0	360	43	murine	murine	JJ
cord-010570-ytv7dwr0	360	44	monoclonal	monoclonal	JJ
cord-010570-ytv7dwr0	360	45	anti	anti	JJ
cord-010570-ytv7dwr0	360	46	-	-	JJ
cord-010570-ytv7dwr0	360	47	lipid	lipid	JJ
cord-010570-ytv7dwr0	360	48	A	a	DT
cord-010570-ytv7dwr0	360	49	antibody	antibody	NN
cord-010570-ytv7dwr0	360	50	in	in	IN
cord-010570-ytv7dwr0	360	51	bacteremic	bacteremic	JJ
cord-010570-ytv7dwr0	360	52	and	and	CC
cord-010570-ytv7dwr0	360	53	nonbacteremic	nonbacteremic	JJ
cord-010570-ytv7dwr0	360	54	patients	patient	NNS
cord-010570-ytv7dwr0	360	55	Therapy	Therapy	NNP
cord-010570-ytv7dwr0	360	56	with	with	IN
cord-010570-ytv7dwr0	360	57	antibody	antibody	NN
cord-010570-ytv7dwr0	360	58	to	to	TO
cord-010570-ytv7dwr0	360	59	tumor	tumor	NN
cord-010570-ytv7dwr0	360	60	necrosis	necrosis	NN
cord-010570-ytv7dwr0	360	61	factor	factor	NN
cord-010570-ytv7dwr0	360	62	in	in	IN
cord-010570-ytv7dwr0	360	63	sepsis	sepsis	NN
cord-010570-ytv7dwr0	361	1	The	the	DT
cord-010570-ytv7dwr0	361	2	efficacy	efficacy	NN
cord-010570-ytv7dwr0	361	3	of	of	IN
cord-010570-ytv7dwr0	361	4	combination	combination	NN
cord-010570-ytv7dwr0	361	5	immunotherapy	immunotherapy	NN
cord-010570-ytv7dwr0	361	6	in	in	IN
cord-010570-ytv7dwr0	361	7	experimental	experimental	JJ
cord-010570-ytv7dwr0	361	8	Pseudomonas	Pseudomonas	NNP
cord-010570-ytv7dwr0	361	9	sepsis	sepsis	NN
cord-010570-ytv7dwr0	361	10	Microbiology	microbiology	NN
cord-010570-ytv7dwr0	361	11	of	of	IN
cord-010570-ytv7dwr0	361	12	toxic	toxic	JJ
cord-010570-ytv7dwr0	361	13	shock	shock	NN
cord-010570-ytv7dwr0	361	14	syndrome	syndrome	NN
cord-010570-ytv7dwr0	361	15	:	:	:
cord-010570-ytv7dwr0	361	16	overview	overview	NNP
cord-010570-ytv7dwr0	361	17	Association	Association	NNP
cord-010570-ytv7dwr0	361	18	of	of	IN
cord-010570-ytv7dwr0	361	19	phenotypic	phenotypic	JJ
cord-010570-ytv7dwr0	361	20	and	and	CC
cord-010570-ytv7dwr0	361	21	genotypic	genotypic	JJ
cord-010570-ytv7dwr0	361	22	characteristics	characteristic	NNS
cord-010570-ytv7dwr0	361	23	of	of	IN
cord-010570-ytv7dwr0	361	24	invasive	invasive	JJ
cord-010570-ytv7dwr0	361	25	Streptococcus	streptococcus	NN
cord-010570-ytv7dwr0	361	26	pyogenes	pyogene	NNS
cord-010570-ytv7dwr0	361	27	isolates	isolate	VBZ
cord-010570-ytv7dwr0	361	28	with	with	IN
cord-010570-ytv7dwr0	361	29	clinical	clinical	JJ
cord-010570-ytv7dwr0	361	30	components	component	NNS
cord-010570-ytv7dwr0	361	31	of	of	IN
cord-010570-ytv7dwr0	362	1	streptococcal	streptococcal	JJ
cord-010570-ytv7dwr0	362	2	toxic	toxic	JJ
cord-010570-ytv7dwr0	362	3	shock	shock	NN
cord-010570-ytv7dwr0	362	4	syndrome	syndrome	NN
cord-010570-ytv7dwr0	362	5	Intravenous	intravenous	JJ
cord-010570-ytv7dwr0	362	6	immunoglobulin	immunoglobulin	NN
cord-010570-ytv7dwr0	362	7	therapy	therapy	NN
cord-010570-ytv7dwr0	362	8	for	for	IN
cord-010570-ytv7dwr0	362	9	toxic	toxic	JJ
cord-010570-ytv7dwr0	362	10	shock	shock	NN
cord-010570-ytv7dwr0	362	11	syndrome	syndrome	NN
cord-010570-ytv7dwr0	362	12	Human	human	JJ
cord-010570-ytv7dwr0	362	13	combinatorial	combinatorial	JJ
cord-010570-ytv7dwr0	362	14	antibody	antibody	NN
cord-010570-ytv7dwr0	362	15	libraries	library	NNS
cord-010570-ytv7dwr0	362	16	to	to	IN
cord-010570-ytv7dwr0	362	17	hepatitis	hepatitis	NNP
cord-010570-ytv7dwr0	362	18	B	B	NNP
cord-010570-ytv7dwr0	362	19	surface	surface	NN
cord-010570-ytv7dwr0	362	20	antigen	antigen	NN
cord-010570-ytv7dwr0	362	21	Passive	passive	JJ
cord-010570-ytv7dwr0	362	22	immunization	immunization	NN
cord-010570-ytv7dwr0	362	23	for	for	IN
cord-010570-ytv7dwr0	362	24	the	the	DT
cord-010570-ytv7dwr0	362	25	prevention	prevention	NN
cord-010570-ytv7dwr0	362	26	and	and	CC
cord-010570-ytv7dwr0	362	27	treatment	treatment	NN
cord-010570-ytv7dwr0	362	28	ofHIV	ofhiv	CD
cord-010570-ytv7dwr0	362	29	infection	infection	NN
cord-010570-ytv7dwr0	362	30	Human	Human	NNP
cord-010570-ytv7dwr0	362	31	monoclonal	monoclonal	JJ
cord-010570-ytv7dwr0	362	32	Fab	fab	JJ
cord-010570-ytv7dwr0	362	33	fragments	fragment	NNS
cord-010570-ytv7dwr0	362	34	derived	derive	VBN
cord-010570-ytv7dwr0	362	35	from	from	IN
cord-010570-ytv7dwr0	362	36	a	a	DT
cord-010570-ytv7dwr0	362	37	combinatorial	combinatorial	JJ
cord-010570-ytv7dwr0	362	38	library	library	NN
cord-010570-ytv7dwr0	362	39	bind	bind	NN
cord-010570-ytv7dwr0	362	40	to	to	IN
cord-010570-ytv7dwr0	362	41	respiratory	respiratory	JJ
cord-010570-ytv7dwr0	362	42	syncytial	syncytial	JJ
cord-010570-ytv7dwr0	362	43	virus	virus	NN
cord-010570-ytv7dwr0	362	44	F	F	NNP
cord-010570-ytv7dwr0	362	45	glycoprotein	glycoprotein	NN
cord-010570-ytv7dwr0	362	46	and	and	CC
cord-010570-ytv7dwr0	362	47	neutralize	neutralize	VB
cord-010570-ytv7dwr0	362	48	infectivity	infectivity	NN
cord-010570-ytv7dwr0	362	49	Efficacy	Efficacy	NNP
cord-010570-ytv7dwr0	362	50	of	of	IN
cord-010570-ytv7dwr0	362	51	human	human	JJ
cord-010570-ytv7dwr0	362	52	immunoglobulin	immunoglobulin	NN
cord-010570-ytv7dwr0	362	53	and	and	CC
cord-010570-ytv7dwr0	362	54	penicillin	penicillin	NN
cord-010570-ytv7dwr0	362	55	G	g	NN
cord-010570-ytv7dwr0	362	56	in	in	IN
cord-010570-ytv7dwr0	362	57	treatment	treatment	NN
cord-010570-ytv7dwr0	362	58	of	of	IN
cord-010570-ytv7dwr0	362	59	experimental	experimental	JJ
cord-010570-ytv7dwr0	362	60	group	group	NN
cord-010570-ytv7dwr0	362	61	B	B	NNP
cord-010570-ytv7dwr0	362	62	streptococcal	streptococcal	JJ
cord-010570-ytv7dwr0	362	63	infection	infection	NN
cord-010570-ytv7dwr0	362	64	Protection	Protection	NNP
cord-010570-ytv7dwr0	362	65	of	of	IN
cord-010570-ytv7dwr0	362	66	mice	mouse	NNS
cord-010570-ytv7dwr0	362	67	against	against	IN
cord-010570-ytv7dwr0	362	68	meningococcus	meningococcus	NN
cord-010570-ytv7dwr0	362	69	infection	infection	NN
cord-010570-ytv7dwr0	362	70	by	by	IN
cord-010570-ytv7dwr0	362	71	polyvalent	polyvalent	JJ
cord-010570-ytv7dwr0	362	72	antimeningococcic	antimeningococcic	NN
cord-010570-ytv7dwr0	362	73	serum	serum	NN
cord-010570-ytv7dwr0	363	1	Combined	combined	JJ
cord-010570-ytv7dwr0	363	2	protective	protective	JJ
cord-010570-ytv7dwr0	363	3	action	action	NN
cord-010570-ytv7dwr0	363	4	of	of	IN
cord-010570-ytv7dwr0	363	5	human	human	JJ
cord-010570-ytv7dwr0	363	6	gamma	gamma	NN
cord-010570-ytv7dwr0	363	7	globulin	globulin	NN
cord-010570-ytv7dwr0	363	8	and	and	CC
cord-010570-ytv7dwr0	363	9	antibiotics	antibiotic	NNS
cord-010570-ytv7dwr0	363	10	when	when	WRB
cord-010570-ytv7dwr0	363	11	administered	administer	VBN
cord-010570-ytv7dwr0	363	12	simultaneously	simultaneously	RB
cord-010570-ytv7dwr0	363	13	in	in	IN
cord-010570-ytv7dwr0	363	14	experimental	experimental	JJ
cord-010570-ytv7dwr0	363	15	staphylococcal	staphylococcal	JJ
cord-010570-ytv7dwr0	363	16	infections	infection	NNS
cord-010570-ytv7dwr0	363	17	Synergism	synergism	NN
cord-010570-ytv7dwr0	363	18	between	between	IN
cord-010570-ytv7dwr0	363	19	human	human	JJ
cord-010570-ytv7dwr0	363	20	gamma	gamma	NN
cord-010570-ytv7dwr0	363	21	globulin	globulin	NNP
cord-010570-ytv7dwr0	363	22	and	and	CC
cord-010570-ytv7dwr0	363	23	chioroamphenicol	chioroamphenicol	NNP
cord-010570-ytv7dwr0	363	24	in	in	IN
cord-010570-ytv7dwr0	363	25	the	the	DT
cord-010570-ytv7dwr0	363	26	treatment	treatment	NN
cord-010570-ytv7dwr0	363	27	of	of	IN
cord-010570-ytv7dwr0	363	28	experimental	experimental	JJ
cord-010570-ytv7dwr0	363	29	bacterial	bacterial	JJ
cord-010570-ytv7dwr0	363	30	infections	infection	NNS
cord-010570-ytv7dwr0	363	31	Combined	combine	VBN
cord-010570-ytv7dwr0	363	32	serum	serum	NN
cord-010570-ytv7dwr0	363	33	and	and	CC
cord-010570-ytv7dwr0	363	34	sulphanilamide	sulphanilamide	NN
cord-010570-ytv7dwr0	363	35	in	in	IN
cord-010570-ytv7dwr0	363	36	the	the	DT
cord-010570-ytv7dwr0	363	37	treatment	treatment	NN
cord-010570-ytv7dwr0	363	38	of	of	IN
cord-010570-ytv7dwr0	363	39	streptococcal	streptococcal	JJ
cord-010570-ytv7dwr0	363	40	infections	infection	NNS
cord-010570-ytv7dwr0	363	41	in	in	IN
cord-010570-ytv7dwr0	363	42	mice	mouse	NNS
cord-010570-ytv7dwr0	363	43	Monoclonal	monoclonal	JJ
cord-010570-ytv7dwr0	363	44	antibodies	antibody	NNS
cord-010570-ytv7dwr0	363	45	for	for	IN
cord-010570-ytv7dwr0	363	46	treatment	treatment	NN
cord-010570-ytv7dwr0	363	47	of	of	IN
cord-010570-ytv7dwr0	363	48	gram	gram	NN
cord-010570-ytv7dwr0	363	49	-	-	HYPH
cord-010570-ytv7dwr0	363	50	negative	negative	JJ
cord-010570-ytv7dwr0	363	51	infections	infection	NNS
cord-010570-ytv7dwr0	363	52	Efficacy	Efficacy	NNP
cord-010570-ytv7dwr0	363	53	of	of	IN
cord-010570-ytv7dwr0	363	54	anti	anti	JJ
cord-010570-ytv7dwr0	363	55	-	-	JJ
cord-010570-ytv7dwr0	363	56	endotoxin	endotoxin	JJ
cord-010570-ytv7dwr0	363	57	monoclonal	monoclonal	JJ
cord-010570-ytv7dwr0	363	58	antibody	antibody	NN
cord-010570-ytv7dwr0	363	59	E5	e5	NN
cord-010570-ytv7dwr0	363	60	alone	alone	RB
cord-010570-ytv7dwr0	363	61	or	or	CC
cord-010570-ytv7dwr0	363	62	in	in	IN
cord-010570-ytv7dwr0	363	63	combination	combination	NN
cord-010570-ytv7dwr0	363	64	with	with	IN
cord-010570-ytv7dwr0	363	65	ciprofloxacin	ciprofloxacin	NN
cord-010570-ytv7dwr0	363	66	in	in	IN
cord-010570-ytv7dwr0	363	67	neutropenic	neutropenic	JJ
cord-010570-ytv7dwr0	363	68	rats	rat	NNS
cord-010570-ytv7dwr0	363	69	with	with	IN
cord-010570-ytv7dwr0	363	70	Pseudomonas	Pseudomonas	NNP
cord-010570-ytv7dwr0	363	71	sepsis	sepsis	NN
cord-010570-ytv7dwr0	364	1	Praziquantelinduced	praziquantelinduced	JJ
cord-010570-ytv7dwr0	364	2	exposure	exposure	NN
cord-010570-ytv7dwr0	364	3	of	of	IN
cord-010570-ytv7dwr0	364	4	Schistosoma	Schistosoma	NNP
cord-010570-ytv7dwr0	364	5	mansoni	mansoni	NN
cord-010570-ytv7dwr0	364	6	alkaline	alkaline	JJ
cord-010570-ytv7dwr0	364	7	phosphatase	phosphatase	NN
cord-010570-ytv7dwr0	364	8	:	:	:
cord-010570-ytv7dwr0	364	9	drugantibody	drugantibody	NN
cord-010570-ytv7dwr0	364	10	synergy	synergy	NN
cord-010570-ytv7dwr0	364	11	which	which	WDT
cord-010570-ytv7dwr0	364	12	acts	act	VBZ
cord-010570-ytv7dwr0	364	13	preferentially	preferentially	RB
cord-010570-ytv7dwr0	364	14	against	against	IN
cord-010570-ytv7dwr0	364	15	female	female	JJ
cord-010570-ytv7dwr0	364	16	worms	worm	NNS
cord-010570-ytv7dwr0	364	17	.	.	.
cord-010570-ytv7dwr0	365	1	Parasite	parasite	NN
cord-010570-ytv7dwr0	365	2	Immuno11994	Immuno11994	NNP
cord-010570-ytv7dwr0	365	3	Effects	effect	NNS
cord-010570-ytv7dwr0	365	4	of	of	IN
cord-010570-ytv7dwr0	365	5	immunoglobulin	immunoglobulin	NN
cord-010570-ytv7dwr0	365	6	G	g	NN
cord-010570-ytv7dwr0	365	7	and	and	CC
cord-010570-ytv7dwr0	365	8	low	low	JJ
cord-010570-ytv7dwr0	365	9	-	-	HYPH
cord-010570-ytv7dwr0	365	10	dose	dose	NN
cord-010570-ytv7dwr0	365	11	amphotericin	amphotericin	NNS
cord-010570-ytv7dwr0	365	12	B	b	NN
cord-010570-ytv7dwr0	365	13	on	on	IN
cord-010570-ytv7dwr0	365	14	Candida	Candida	NNP
cord-010570-ytv7dwr0	365	15	albicans	albican	NNS
cord-010570-ytv7dwr0	365	16	infections	infection	NNS
cord-010570-ytv7dwr0	365	17	in	in	IN
cord-010570-ytv7dwr0	365	18	burned	burn	VBN
cord-010570-ytv7dwr0	365	19	mice	mouse	NNS
cord-010570-ytv7dwr0	365	20	Combination	Combination	NNP
cord-010570-ytv7dwr0	365	21	of	of	IN
cord-010570-ytv7dwr0	365	22	5-flucytosine	5-flucytosine	CD
cord-010570-ytv7dwr0	365	23	and	and	CC
cord-010570-ytv7dwr0	365	24	capsule	capsule	NN
cord-010570-ytv7dwr0	365	25	-	-	HYPH
cord-010570-ytv7dwr0	365	26	binding	bind	VBG
cord-010570-ytv7dwr0	365	27	monoclonal	monoclonal	JJ
cord-010570-ytv7dwr0	365	28	antibody	antibody	NN
cord-010570-ytv7dwr0	365	29	in	in	IN
cord-010570-ytv7dwr0	365	30	therapy	therapy	NN
cord-010570-ytv7dwr0	365	31	of	of	IN
cord-010570-ytv7dwr0	365	32	Cryptococcus	Cryptococcus	NNP
cord-010570-ytv7dwr0	365	33	neoformans	neoforman	VBZ
cord-010570-ytv7dwr0	365	34	infection	infection	NN
cord-010570-ytv7dwr0	366	1	Enhanced	enhanced	JJ
cord-010570-ytv7dwr0	366	2	treatment	treatment	NN
cord-010570-ytv7dwr0	366	3	of	of	IN
cord-010570-ytv7dwr0	366	4	Lassa	Lassa	NNP
cord-010570-ytv7dwr0	366	5	fever	fever	NN
cord-010570-ytv7dwr0	366	6	by	by	IN
cord-010570-ytv7dwr0	366	7	immune	immune	JJ
cord-010570-ytv7dwr0	366	8	plasma	plasma	NN
cord-010570-ytv7dwr0	366	9	combined	combine	VBN
cord-010570-ytv7dwr0	366	10	with	with	IN
cord-010570-ytv7dwr0	366	11	ribavirin	ribavirin	NN
cord-010570-ytv7dwr0	366	12	in	in	IN
cord-010570-ytv7dwr0	366	13	cynomolgus	cynomolgus	JJ
cord-010570-ytv7dwr0	366	14	monkeys	monkey	NNS
cord-010570-ytv7dwr0	366	15	-3-Dihydroxy-2-Propoxymethyl	-3-dihydroxy-2-propoxymethyl	VBP
cord-010570-ytv7dwr0	366	16	)	)	-RRB-
cord-010570-ytv7dwr0	366	17	guanine	guanine	NN
cord-010570-ytv7dwr0	366	18	prevents	prevent	VBZ
cord-010570-ytv7dwr0	366	19	death	death	NN
cord-010570-ytv7dwr0	366	20	but	but	CC
cord-010570-ytv7dwr0	366	21	not	not	RB
cord-010570-ytv7dwr0	366	22	immunity	immunity	NN
cord-010570-ytv7dwr0	366	23	in	in	IN
cord-010570-ytv7dwr0	367	1	murine	murine	JJ
cord-010570-ytv7dwr0	367	2	cytomegalovirus	cytomegalovirus	NN
cord-010570-ytv7dwr0	367	3	-	-	HYPH
cord-010570-ytv7dwr0	367	4	infected	infect	VBN
cord-010570-ytv7dwr0	367	5	normal	normal	JJ
cord-010570-ytv7dwr0	367	6	and	and	CC
cord-010570-ytv7dwr0	367	7	immunosuppressed	immunosuppressed	JJ
cord-010570-ytv7dwr0	367	8	BALB	BALB	NNP
cord-010570-ytv7dwr0	367	9	/	/	SYM
cord-010570-ytv7dwr0	367	10	c	c	NN
cord-010570-ytv7dwr0	367	11	mice	mouse	NNS
cord-010570-ytv7dwr0	367	12	Combined	combine	VBN
cord-010570-ytv7dwr0	367	13	effects	effect	NNS
cord-010570-ytv7dwr0	367	14	of	of	IN
cord-010570-ytv7dwr0	367	15	acycloguanosine	acycloguanosine	NN
cord-010570-ytv7dwr0	367	16	and	and	CC
cord-010570-ytv7dwr0	367	17	humoral	humoral	JJ
cord-010570-ytv7dwr0	367	18	antibodies	antibody	NNS
cord-010570-ytv7dwr0	367	19	in	in	IN
cord-010570-ytv7dwr0	367	20	experimental	experimental	JJ
cord-010570-ytv7dwr0	367	21	encephalitis	encephalitis	NN
cord-010570-ytv7dwr0	367	22	due	due	IN
cord-010570-ytv7dwr0	367	23	to	to	IN
cord-010570-ytv7dwr0	367	24	Herpesvirus	Herpesvirus	NNP
cord-010570-ytv7dwr0	367	25	hominis	hominis	NN
cord-010570-ytv7dwr0	367	26	Synergistic	synergistic	JJ
cord-010570-ytv7dwr0	367	27	antiviral	antiviral	JJ
cord-010570-ytv7dwr0	367	28	effects	effect	NNS
cord-010570-ytv7dwr0	367	29	of	of	IN
cord-010570-ytv7dwr0	367	30	adenine	adenine	NN
cord-010570-ytv7dwr0	367	31	arabinoside	arabinoside	NN
cord-010570-ytv7dwr0	367	32	and	and	CC
cord-010570-ytv7dwr0	367	33	humoral	humoral	JJ
cord-010570-ytv7dwr0	367	34	antibodies	antibody	NNS
cord-010570-ytv7dwr0	367	35	in	in	IN
cord-010570-ytv7dwr0	367	36	experimental	experimental	JJ
cord-010570-ytv7dwr0	367	37	encephalitis	encephalitis	NN
cord-010570-ytv7dwr0	367	38	due	due	IN
cord-010570-ytv7dwr0	367	39	to	to	IN
cord-010570-ytv7dwr0	367	40	Herpesvirus	Herpesvirus	NNP
cord-010570-ytv7dwr0	367	41	hominis	hominis	NN
cord-010570-ytv7dwr0	367	42	Unequalled	Unequalled	NNP
cord-010570-ytv7dwr0	367	43	but	but	CC
cord-010570-ytv7dwr0	367	44	unobtainable	unobtainable	JJ