id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-354720-fu19u2b0	White-Dzuro, Gabrielle	Multisystem effects of COVID-19: a concise review for practitioners	2020-11-04		.txt	text/plain	5088	285	35	It is important that clinicians managing critically ill COVID-19 patients be aware of the multisystem impact of the disease so that care can be focused on the prevention of end-organ injuries to potentially improve clinical outcomes. It is important that clinicians managing these critically ill patients be aware of the multisystem impact of the disease so that care can be focused on the prevention of end-organ injuries to potentially improve clinical outcomes. The indirect effects of the virus result from the host's response to the viral infection, and are associated with a cytokine storm characterized by very high circulating levels of pro-inflammatory cytokines, including tumor necrosis factor (TNF)-α, interleukins, granulocyte-colony stimulating factor, and chemokines [9] . include direct viral damage of nervous tissue, injury resulting from the excessive inflammatory response, unintended host immune response effects after the acute infection (e.g., Guillain-Barré syndrome as reported in a case series of four patients [24] ), and injury resulting from the effects of systemic illness.	./cache/cord-354720-fu19u2b0.txt	./txt/cord-354720-fu19u2b0.txt