id author title date pages extension mime words sentences flesch summary cache txt cord-353787-24c98ug8 Jackson, J. A. Immunology in wild nonmodel rodents: an ecological context for studies of health and disease 2015-04-27 .txt text/plain 8770 333 26 Measurement of immune expression may help define individual heterogeneity in infectious disease susceptibility and transmission and facilitate our understanding of infection dynamics and risk in the natural environment; furthermore, it may provide a means of surveillance that can filter individuals carrying previously unknown acute infections of potential ecological or zoonotic importance. Potentiating much of this is the possibility of combining gene expression profiles with analytical tools derived from ecology and systems biology to reverse engineer interaction networks between immune responses, other organismal traits and the environment (including symbiont exposures), revealing regulatory architecture. Studies in wild field voles, briefly reviewed below, have aimed to identify distributional infection patterns associated with different antipathogen strategies in natural populations and to link these to expression signatures in immune-relevant genes. ./cache/cord-353787-24c98ug8.txt ./txt/cord-353787-24c98ug8.txt