id author title date pages extension mime words sentences flesch summary cache txt cord-348844-4rpbsj48 Wessel, Lindsay Public health interventions for epidemics: implications for multiple infection waves 2011-02-25 .txt text/plain 4680 206 40 METHODS: We develop mean-field and stochastic epidemiological models for disease transmission, and perform simulations to show how control measures, such as drug treatment and isolation of ill individuals, can influence the epidemic profile and generate sequences of infection waves with different characteristics. In this study, we consider the occurrence of multiple infection waves of a pathogen from a public health perspective, and develop mathematical models to investigate how intervention measures may affect the transmission dynamics in a population. These parameters may reflect the effectiveness of intervention strategies (e.g., treatment or isolation of infected cases) in reducing disease transmission, or their epidemiological consequences (e.g., emergence of drug resistance), and may therefore play an important role in determining the outcome of disease control activities. For the purpose of this investigation, we develop both mean-field and stochastic epidemiological models that describe the transmission dynamics of a disease in the population, and incorporate treatment and isolation of infected cases as control measures. ./cache/cord-348844-4rpbsj48.txt ./txt/cord-348844-4rpbsj48.txt