id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-347000-zxytdb0b	Foweraker, Juliet	Recent advances in the microbiology of respiratory tract infection in cystic fibrosis	2009-01-20		.txt	text/plain	6699	419	42	The range of micro-organisms causing infection differs from those in patients without CF with the commonest pathogens being Staphylococcus aureus and Pseudomonas aeruginosa. 17 Streptococcus pneumoniae from CF respiratory samples were better at producing biofilms in vitro than blood culture isolates from non-CF patients, 18 which suggests that these organisms have the ability to persist in the CF lung. 31 The role of current methods of synergy testing is controversial, but there is a definite need for clinically validated in vitro tests to guide treatment of multi-and pan-resistant bacteria at acute exacerbation and when patients receive lung transplants. Phenotypic variability of Pseudomonas aeruginosa in sputa from patients with acute infective exacerbation of cystic fibrosis and its impact on the validity of antimicrobial susceptibility testing Hypermutation is a key factor in development of multiple-antimicrobial resistance in Pseudomonas aeruginosa strains causing chronic lung infections Evolving epidemiology of Pseudomonas aeruginosa and the Burkholderia cepacia complex in cystic fibrosis lung infection	./cache/cord-347000-zxytdb0b.txt	./txt/cord-347000-zxytdb0b.txt