id author title date pages extension mime words sentences flesch summary cache txt cord-346673-kyc1wks5 NICKBAKHSH, S. Extensive multiplex PCR diagnostics reveal new insights into the epidemiology of viral respiratory infections 2016-03-02 .txt text/plain 5415 237 41 In particular, our study shows that (i) human coronavirus infections are more common during influenza seasons and in co-infections than previously recognized, (ii) factors associated with co-infection differ from those associated with viral infection overall, (iii) virus prevalence has increased over time especially in infants aged <1 year, and (iv) viral infection risk is greater in the post-2009 pandemic era, likely reflecting a widespread change in the viral population that warrants further investigation. We analysed diagnostic data generated by NHSGGC using multiplex PCR from 2005 to 2013 with the following objectives: (i) to describe testing and virus prevalence trends, (ii) to examine temporal and patient subgroup distributions for each individual virus, and (iii) to compare factors associated with overall viral infection and co-infection using statistical modelling, in order to provide robust and timely estimates of who is most at risk of viral-associated respiratory illness, and when, within a major urban UK population. ./cache/cord-346673-kyc1wks5.txt ./txt/cord-346673-kyc1wks5.txt