id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-332379-340wczmq	Pennington, Matthew R.	Disparate Entry of Adenoviruses Dictates Differential Innate Immune Responses on the Ocular Surface	2019-09-13		.txt	text/plain	11584	604	36	These findings suggest that adenoviruses may stimulate specific pattern recognition receptors in an entry/trafficking-dependent manner, leading to distinct immune responses dependent on the virus/cell type combination. Additional work is needed to understand the specific connections between adenoviral entry and the stimulation of innate immune responses by the various cell types present on the ocular surface. Innate immune responses to adenoviruses rely on the detection of pathogen-associated molecular patterns (PAMPs): distinct ligands present on the external surfaces, and nucleic acids of pathogens (but absent in the host) that feature molecular signatures able to be recognized by pattern recognition receptors (PRR) on or in infected host cells [43] [44] [45] [46] . Innate immune responses to adenoviruses rely on the detection of pathogen-associated molecular patterns (PAMPs): distinct ligands present on the external surfaces, and nucleic acids of pathogens (but absent in the host) that feature molecular signatures able to be recognized by pattern recognition receptors (PRR) on or in infected host cells [43] [44] [45] [46] .	./cache/cord-332379-340wczmq.txt	./txt/cord-332379-340wczmq.txt