id author title date pages extension mime words sentences flesch summary cache txt cord-331500-l3hkn2li Luyt, Charles-Edouard Pulmonary infections complicating ARDS 2020-11-11 .txt text/plain 7544 358 26 Whatever the initial lung injury, patients with ARDS are prone to develop secondary pulmonary infection, namely ventilator-associated pneumonia (VAP). While glucocorticoids are classically considered as immunosuppressive drugs, it has been shown that they can prevent the immune reprogramming observed after inflammatory response [16] , thus limiting the susceptibility of patients admitted to the intensive care unit (ICU) to respiratory complications such as pneumonia or ARDS and improving outcomes of patients with ARDS [17] . Peripheral blood markers have the advantage of avoiding the need for bronchoscopic sampling and are therefore easier to obtain; however, they are generally less able to discriminate pneumonia from other infections Table 1 Summary of host-based biomarkers for diagnosis of pneumonia in ARDS ARDS acute respiratory distress syndrome, RCT randomized controlled trial, sTREM soluble triggering receptor expressed on myeloid cells, VAP ventilator-associated pneumonia, HLA human leukocyte antigen ./cache/cord-331500-l3hkn2li.txt ./txt/cord-331500-l3hkn2li.txt