id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-324788-echu0zmf	Aich, Palok	Modern approaches to understanding stress and disease susceptibility: A review with special emphasis on respiratory disease	2009-07-30		.txt	text/plain	7667	396	36	The current review focuses on (a) the effects of psychological stressors in humans and animals, (b) various methodologies employed to understand stress responses and their outcomes, and (c) the current status of the attempts to correlate stress and disease with respiratory disease as model system. While many genes and environmental factors contribute to susceptibility and resistance to autoimmune/infl ammatory diseases, a full understanding of the molecular mechanisms by which a combination of neuropeptides, neurohormones and neurotransmitters can modulate immune responses is essential for effective design of future interventions. We conducted bovine microarray analyses of RNA isolated from blood mononuclear cells to determine if changes in gene expression correlated with either stress or the severity of BRD infection; results support the conclusion that differential regulation of pro-infl ammatory responses is a major mechanism contributing to increased disease susceptibility.	./cache/cord-324788-echu0zmf.txt	./txt/cord-324788-echu0zmf.txt