id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-320663-xypg6evo	Market, Marisa	Flattening the COVID-19 Curve With Natural Killer Cell Based Immunotherapies	2020-06-23		.txt	text/plain	14038	659	42	A common feature of coronavirus infections is that significant morbidity and mortality is associated with lung injury and acute respiratory distress syndrome resulting from an exaggerated immune response, of which NK cells are an important component. Natural Killer (NK) cells are a key component of the innate immune system and are critical in the response to many viral infections in humans and animal models (1) (2) (3) . Altogether these studies show that during acute CoV infection, inflammatory monocyte-macrophages and neutrophils accumulate in the lungs and produce cytokines and chemokines that induce the activation and migration of lymphocytes, including NK cells, to the lungs, where they could be one of the main producers of IFN-γ (148). Studies have reported that patients infected with SARS-CoV-2 have lower levels of circulating NK cells and these express a greater level of inhibitory receptors (e.g., NKG2A) while producing less IFN-γ (127, 129, 130) .	./cache/cord-320663-xypg6evo.txt	./txt/cord-320663-xypg6evo.txt