id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-320548-oigyut2k	Zumla, Alimuddin	Emerging novel and antimicrobial-resistant respiratory tract infections: new drug development and therapeutic options	2014-09-01		.txt	text/plain	8120	430	36	19 In patients admitted to hospital with severe infl uenza A H7N9 infection, reduction of viral load after treatment with oseltamivir correlated with improved outcome, whereas the emergence of virus resistant to neuraminidase inhibitors that harbours an Arg292Lys substitution is associated with poor outcomes and poor response to oseltamivir and peramivir. Several observational studies show that systemic corticosteroids given for 2009 pandemic infl uenza A H1N1-associated viral pneumonia increased the risk of mortality and morbidity (eg, secondary infections), especially when there was a delay in initiation, or absence of, eff ective antiviral therapy. Several observational studies have shown that systemic corticosteroids given for 2009 pandemic infl uenza A H1N1-asssociated viral pneumonia or acute respiratory distress syndrome increased the risk of mortality and morbidity (eg, secondary bacterial or fungal infections), especially if there is delay or lack of eff ective antiviral therapy.	./cache/cord-320548-oigyut2k.txt	./txt/cord-320548-oigyut2k.txt