id author title date pages extension mime words sentences flesch summary cache txt cord-314600-x8mmuf3y Biagi, Carlotta Rhinovirus Infection in Children with Acute Bronchiolitis and Its Impact on Recurrent Wheezing and Asthma Development 2020-10-21 .txt text/plain 5817 259 43 Bronchiolitis is defined by the American Academy of Pediatrics (AAP) as a constellation of signs and symptoms, including a viral upper respiratory tract prodrome, followed by increased respiratory effort and wheezing in children under the age of two [9] .In Europe, by contrast, the term bronchiolitis is generally referred to as a first episode of acute lower airway infection in infants younger than one year [7] . Many studies have investigated whether the severity of acute bronchiolitis-mainly measured by clinical score indexes (CSIs), oxygen requirement, ventilatory support, Pediatric Intensive Care Unit (PICU) admission, and length of hospital stay (LOS)-is associated with specific viral infections or co-infections, with controversial results. Finally, also in a prospective multicenter study focusing on 363 hospitalized infants with moderate-severe bronchiolitis, no significant differences appeared between RV infection-even when they considered viral types-and other single virus-infections regarding either oxygen requirement, ventilation need, or nasogastric feeding [31] . ./cache/cord-314600-x8mmuf3y.txt ./txt/cord-314600-x8mmuf3y.txt