id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-310942-191m0e65	Boga, Jose Antonio	Beneficial actions of melatonin in the management of viral infections: a new use for this “molecular handyman”?	2012-04-18		.txt	text/plain	7208	362	32	The potential protective mechanisms include melatonin acting as a free radical scavenger, an antioxidant enzyme inducer, a positive regulator of immune functions and an inhibitor of inflammation, as well as a regulator of programmed cell death (PCD) [ Table 2 ]. Melatonin treatment also caused a rise in protein expression of the nuclear factor erythroid 2 (Nrf2), a transcription factor that plays a critical role by binding to the antioxidant response element in the promoter region of a number of genes encoding for antioxidant and detoxifying enzymes in several types of cells and tissues [109] . Respiratory syncytial virus infection of human respiratory epithelial cells enhances inducible nitric oxide synthase gene expression Melatonin decreases nitric oxide production and lipid peroxidation and increases interleukin-1 beta in the brain of mice infected by the Venezuelan equine encephalomyelitis virus	./cache/cord-310942-191m0e65.txt	./txt/cord-310942-191m0e65.txt