id author title date pages extension mime words sentences flesch summary cache txt cord-276348-vr5fit8r Ogra, Pearay L. Respiratory syncytial virus: The virus, the disease and the immune response 2004-01-31 .txt text/plain 4788 282 44 Premature babies born at 30–35 weeks of gestation, infants with cyanotic congenital heart disease, HIV-infected subjects, and patients on intensive immunosuppressive therapy especially after bone marrow transplant are considered to be at risk for increased mortality and morbidity during RSV infection. Recurrent wheezing for up to 5 to 7 years of age and established airway disease has been observed in a significant number of children with a strong family history of allergy, after primary infection or reinfection with RSV. Children at increased risk from RSV infection include young infants with prematurity, bronchopulmonary dysplasia, congenital heart disease, congenital or acquired immunodeficiency, subjects with hematologic malignancies, patients with bone-marrow or organ transplants, and cystic fibrosis. 6 It is important to recognise that virtually all children who get infected with RSV develop virus-specific IgE homocytotropic antibody in the respiratory tract. ./cache/cord-276348-vr5fit8r.txt ./txt/cord-276348-vr5fit8r.txt