id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-275795-ee7qyw5h	Monette, Anne	T Lymphocytes as Measurable Targets of Protection and Vaccination Against Viral Disorders	2018-10-24		.txt	text/plain	28265	1205	38	We focus on immunity generated against both natural infection and vaccination, where a steady shift in conferred vaccination immunogenicity is observed from quantifying activated and proliferating, long-lived effector memory T cell subsets, as the prominent biomarkers of long-term immunity against viruses and their associated disorders causing high morbidity and mortality rates. Since that time, the occurrence of epidemics and outbreaks are now at lower risk, following the introduction of massive vaccination programs able to induce immune system targeting of viruses causing severe disorders affecting distinct geographical locations, and with many epidemiological reports demonstrating long-term efficacy of viral control of non-naïve populations. This approach is being developed to use virus-infected cell-killing antibodies that produce an antiviral environment; these termed antibody-dependent cellular cytotoxicity (ADCC)-mediating antibodies, which are predicted to link innate and adaptive immune responses, and is becoming possible due to new technologies for rapid isolation and characterization of monoclonal antibodies targeting conserved regions of influenza virus, reviewed in Jegaskanda et al.	./cache/cord-275795-ee7qyw5h.txt	./txt/cord-275795-ee7qyw5h.txt