id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-269095-lwank6hk	Jirru, Ermias	Impact of Influenza on Pneumococcal Vaccine Effectiveness during Streptococcus pneumoniae Infection in Aged Murine Lung	2020-06-11		.txt	text/plain	5981	290	36	As recent work has illustrated differential efficacy of Prevnar vaccination in modulating the immune responses of adult mice to post-influenza infection with a serotype 3 strain of Streptococcus pneumoniae, we chose to examine the impact of influenza infection on Pneumovax responses during a secondary bacterial infection [30, 40] . When compared to PBS controls, there was no significant increase in cellular recruitment or viral titers in aged adult mice vaccinated with Pneumovax on day 7 post influenza ( Figure 3B,C) . The purpose of our current study was to investigate the role of immune imprinting by influenza on pneumococcal vaccine effectiveness during Streptococcus pneumoniae infection in the aged murine lung. The purpose of our current study was to investigate the role of immune imprinting by influenza on pneumococcal vaccine effectiveness during Streptococcus pneumoniae infection in the aged murine lung.	./cache/cord-269095-lwank6hk.txt	./txt/cord-269095-lwank6hk.txt