id author title date pages extension mime words sentences flesch summary cache txt cord-260605-smkr7b15 Vestby, Lene K. Bacterial Biofilm and its Role in the Pathogenesis of Disease 2020-02-03 .txt text/plain 12145 672 40 However, the biofilm lifestyle of microorganisms were of no interest to medical microbiologists until the early 1970s when Nils Høiby observed a link between the etiology of a persistent infection and aggregates of bacteria in cystic fibrosis patients [1] . This is consistent with the experiments showing that many bacteria causing acute gallbladder infections do not form biofilms on gallstones in the presence of bile [73, 80] . This is consistent with the experiments showing that many bacteria causing acute gallbladder infections do not form biofilms on gallstones in the presence of bile [73, 80] . Several studies have detected higher incidence of Escherichia coli in patients with IBD compared to healthy individuals [90] and although biofilms were not demonstrated in vivo, the isolates were isolated from biopsies after removal of the mucosal layer, indicating adherence to the colonic epithelium and the isolates displayed biofilm forming capacity in vitro [90] . ./cache/cord-260605-smkr7b15.txt ./txt/cord-260605-smkr7b15.txt