id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-259194-9zllvfqb	Cupples, Sandra A.	Transplant Infectious Disease: Implications for Critical Care Nurses	2011-11-02		.txt	text/plain	4469	313	39	4 Patient-related risk factors for infection include older age, poor nutritional status, indwelling catheters, prolonged intubation, postoperative bleeding, blood transfusions, multiorgan dysfunction, comorbidities such as diabetes mellitus and obesity, prolonged hospitalization before VAD implantation, and surgical reexploration. Factors that promote infection in potential organ donors include the use of medical devices and the treatment of patients in certain units that have high rates of bacterial contamination. Risk factors for PTLD include pretransplant EBV-negative serostatus, primary EBV infection, high EBV viral load, CMV serostatus mismatch (recipient is CMV negative and donor is CMV positive), CMV disease, potent rejection treatment, and type of allograft. 27 Risk factors for fungal infections include the use of high-dose corticosteroids and broad-spectrum antibiotics, rejection that requires increased immunosuppression, allograft dysfunction, and a simultaneous infection with an immunomodulating virus such as CMV. The risk of posttransplant mediastinitis is higher if the patient had a mechanical circulatory assist device or a total artificial heart as a bridge to transplantation.	./cache/cord-259194-9zllvfqb.txt	./txt/cord-259194-9zllvfqb.txt