id author title date pages extension mime words sentences flesch summary cache txt cord-257114-pxmflm2c BURGUETE, SERGIO R. Lung transplant infection 2012-12-26 .txt text/plain 11389 648 36 This article will review the common infections that develop in the lung transplant recipient, including the general risk factors for infection in this population, and the most frequent bacterial, viral, fungal and other less frequent opportunistic infections. Resistant Gramnegative organisms pose perhaps the greatest risk, and some studies suggest an association between pretransplant colonizing organisms from patients with suppurative lung disease and pneumonias following LT. A Cochrane Review comparing prophylaxis in different groups of solid organ transplant patients with antivirals versus placebo or no treatment showed a significant reduction in disease (relative risk 0.42), infection (relative risk 0.61), mortality from CMV disease (relative risk 0.26) and allcause mortality (relative risk 0.63). 114 In general, the choice for antifungal prophylaxis depends, in part, on the presence of specific risk factors such as colonization with Aspergillus, presence of airway stents or ischaemia, single lung transplantation, CMV infection, hypogammaglobulinaemia or treatment of acute rejection. ./cache/cord-257114-pxmflm2c.txt ./txt/cord-257114-pxmflm2c.txt