id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-255479-yd5cbwnx	Vu, David M.	Chikungunya Virus	2017-06-30		.txt	text/plain	4097	232	45	Anti-CHIKV antibodies directed against the envelope protein that neutralize the virus in vitro also protect neonatal mice from lethal CHIKV infection in vivo, suggesting that these proteins may be important antigenic lethal targets for development of naturally acquired, or vaccine-elicited protection. Stedman, who reported this "anomalous disease" called "dandy fever" by local residents, noted that the illness "attacked almost every individual in the town," had "extremely low mortality," and was associated with "pains in the joints for weeks after recovery from the acute stage," which were key differences between the 1827 and 1828 West Indies epidemic and previous descriptions of a "break-bone fever" (referring to modern-day dengue fever). For diagnostic confirmation of current and recent infection, a molecular test (typically polymerase chain reaction [PCR]) for the virus and an assay for the presence of specific IgM antibody are required.	./cache/cord-255479-yd5cbwnx.txt	./txt/cord-255479-yd5cbwnx.txt