id author title date pages extension mime words sentences flesch summary cache txt cord-025155-ow3r3469 Lokida, Dewi Underdiagnoses of Rickettsia in patients hospitalized with acute fever in Indonesia: observational study results 2020-05-24 .txt text/plain 4430 271 44 title: Underdiagnoses of Rickettsia in patients hospitalized with acute fever in Indonesia: observational study results METHODS: Acute and convalescent blood from 975 hospitalized non-dengue patients was tested for Rickettsia IgM and IgG by ELISA. For the 103/975 (10.6%) non-dengue patients diagnosed with acute rickettsial infection, presenting symptoms included nausea (72%), headache (69%), vomiting (43%), lethargy (33%), anorexia (32%), arthralgia (30%), myalgia (28%), chills (28%), epigastric pain (28%), and rash (17%). Clinicians should include rickettsioses in their differential diagnosis of fever to guide empiric management; laboratories should support evaluation for rickettsial etiologies; and public policy should be implemented to reduce burden of disease. To characterize the epidemiology of rickettsioses in Indonesia, we performed Rickettsia diagnostic panels on blood from subjects in the Acute Fever Requiring Hospitalization (AFIRE) study [13] . Patients found to have rickettsial infection by reference laboratory testing were identified from INA-RESPOND's [14] AFIRE observational cohort study conducted in Indonesia from 2013 to 2016. ./cache/cord-025155-ow3r3469.txt ./txt/cord-025155-ow3r3469.txt