id author title date pages extension mime words sentences flesch summary cache txt cord-023942-vrs3je1x Powers, Karen S. Acute Pulmonary Infections 2011-12-16 .txt text/plain 11273 673 42 Acute lower respiratory infection is a common cause of morbidity in infants and children, and at times, requires intensive care and mechanical ventilation. Acute lower respiratory infection is a common cause of morbidity in infants and children, and at times, requires intensive care and mechanical ventilation. Viral bronchiolitis remains the leading cause for hospital admission in infancy and the most frequent cause of acute respiratory failure in children admitted to pediatric intensive care units in North America. In a study of hospitalized infants with congenital heart disease infected with RSV, 33% required intensive care, 19% received mechanical ventilation, and 3.4% died. In the 1990s, fi ve randomized trials involving 225 infants, evaluating the effect of nebulized adrenaline (epinephrine) on bronchiolitis showed clinical improvement, with reductions in oxygen requirement, respiratory rate, wheezing, and decrease in pulmonary vascular resistance. High incidence of pulmonary bacterial co-infection in children with severe respiratory syncytial virus (RSV) bronchiolitis ./cache/cord-023942-vrs3je1x.txt ./txt/cord-023942-vrs3je1x.txt