id author title date pages extension mime words sentences flesch summary cache txt cord-022521-r72jtoso Miller, Tracie L. Gastrointestinal Complications of Secondary Immunodeficiency Syndromes 2010-12-27 .txt text/plain 13694 812 36 However, in the United States and other developed countries, severe malnutrition and new cases of perinatal HIV-1 disease are rare because of relatively high standards of living and effective highly active antiretroviral therapies (HAART) given to pregnant HIV-infected women that prevent transmission of HIV to the infants. Examination of both acute simian immunodeficiency virus (SIV) and HIV infection have documented reduced CD4 cell levels in GALT prior to a detectable reduction in T cells of the peripheral blood, highlighting the gastrointestinal tract's role and susceptibility. Previous studies have shown that activated mucosal T cells play a role in the pathogenesis of enteropathy in the human small intestine 37 and can affect the morphology of the villi and crypts in a manner similar to that seen in patients with HIV-1 infection. Immune restoration disease after the treatment of immunodeficient HIV-infected patients with highly active antiretroviral therapy ./cache/cord-022521-r72jtoso.txt ./txt/cord-022521-r72jtoso.txt