id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-022252-9yiuuye3	Mims, Cedric A.	Mechanisms of Cell and Tissue Damage	2013-11-17		.txt	text/plain	28864	1432	48	A few viruses are remarkable because they cause no pathological changes at all in the cell, even during a productive infection in which infectious virus particles are produced. Primary consideration will be given to those substances which are produced under ecologically significant conditions (i.e. in the natural host or relevant animal model) and cause (also in biologically relevant systems) damage to cells or tissues thereby contributing to disease. Here we consider toxins which act on extracellular substances and are responsible for many of the main features of the diseases caused by the infecting organism. Circulating immune complexes are also deposited in the walls of small blood vessels in the skin and elsewhere, where they may induce inflammatory changes.* The prodromal rashes seen in exanthematous virus infections and in hepatitis B are probably caused in this way.	./cache/cord-022252-9yiuuye3.txt	./txt/cord-022252-9yiuuye3.txt