id author title date pages extension mime words sentences flesch summary cache txt cord-021588-ec7udsmw Craighead, John E. Enteric Viral Disease 2007-05-09 .txt text/plain 3474 188 45 This virus and its soon-to-be-discovered close relatives (the so-called Norwalk-like viruses [NLVs]) proved to be important causes of explosive outbreaks of diarrhea in both children and adults. But, this painstaking approach has now yielded evidence to indicate that viruses of at least six families may contribute to enteric illness in children and in adult citizens whose immunity has waned (Figure 32.1, Table 32 .1). The etiological role of these viruses as a cause of intestinal disease was established by demonstrating a temporal association of naturally occurring infections (as demonstrated by stool examination using electron microscopy) with illness and by experimental induction of disease in both human volunteers and experimental animals (Hall et al, 1984) . Volunteer studies have yielded important histological and ultrastructural documentation of the profound but relatively transient changes that occur in the mucosa of the small intestine during the course of infections with NLVs (Agus ei al, 1973; Schreiber ei al, 1973 Schreiber ei al, , 1974 Dolin ei al, 1975) . ./cache/cord-021588-ec7udsmw.txt ./txt/cord-021588-ec7udsmw.txt