id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-017393-kx8kmdej	Herbers, Alexandra	Acute Myelogenous Leukemia and Febrile Neutropenia	2009-08-31		.txt	text/plain	13295	566	31	Despite numerous clinical studies, since the 1970s, no single empirical antibiotic regimen has been shown to be superior for initial treatment of patients who become febrile during a neutropenic episode after therapy with chemotherapy drugs for hematological malignancies (see Table 5 -2) [4, 9, [34] [35] [36] [37] [38] [39] [40] [41] [42] [43] [44] . Similarly, bacteremias due to Staphylococcus aureus, Pseudomonas aeruginosa, and Clostridium species as well as candidemias are more frequently encountered in patients with acute leukemia who suffer from neutropenic enterocolitis or typhlitis, the most serious disturbance of the delicate balance between mucosal damage and microbial flora in the setting of prolonged exposure to antibiotics after intermediate or high-dose cytarabine chemotherapy. In addition, if a persistently neutropenic patient has no complaints and displays no clinical, radiological, or laboratory evidence of infection, cessation of antibiotic therapy or a change to oral antimicrobials should be considered after 4 days without symptoms.	./cache/cord-017393-kx8kmdej.txt	./txt/cord-017393-kx8kmdej.txt