id author title date pages extension mime words sentences flesch summary cache txt cord-017021-n6rpuvwd Marriott, Deborah J. Common Infections Following Lung Transplantation 2018-08-31 .txt text/plain 11695 672 39 • physical factors such as denervation of the allograft resulting in a reduced cough reflex and anastomotic site stenosis with distal infection • the 'net state of immunosuppression'-the result of all factors including host immune system, anti-rejection immunosuppressive therapy and concomitant viral infections such as cytomegalovirus that contribute to a patient's risk of infection • epidemiological exposure to organisms, including donor-derived infections, community acquired infections, travel related infections and healthcare associated infections • the use of prophylactic antimicrobial agents in the post-transplant period Longer treatment is required for severe or disseminated infection or for infection involving the central nervous system and/or bone and joint and in pulmonary disease with ongoing AFB detectable in sputum (>2 months) • streptomycin should not be used in the lung transplant setting because of the associated high-risk of nephrotoxicity. ./cache/cord-017021-n6rpuvwd.txt ./txt/cord-017021-n6rpuvwd.txt