id author title date pages extension mime words sentences flesch summary cache txt cord-017012-yl0vanuh Herberg, Jethro Infectious Diseases and the Kidney 2009 .txt text/plain 23980 1301 34 Renal involvement in infectious diseases may occur by a variety of mechanisms: direct microbial invasion of the renal tissues or collecting system may take place in conditions such as staphylococcal abscess of the kidney as a result of septicemic spread of the organism or as a consequence of ascending infection; damage to the kidney may be caused by the systemic release of endotoxin or other toxins and activation of the inflammatory cascade during septicemia or by a focus of infection distant from the kidney; ischemic damage may result from inadequate perfusion induced by septic shock; the kidney may be damaged by activation of the immunologic pathways or by immune complexes resulting from the infectious process. However, in addition to this post-infection immunologically mediated disorder, in recent years there have been increasing reports of GAS causing acute renal failure as part of an invasive infection with many features of the staphylococcal toxic shock syndrome (28) . ./cache/cord-017012-yl0vanuh.txt ./txt/cord-017012-yl0vanuh.txt