id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-007362-pjpkz6wv	Bielefeldt-Ohmann, Helle	The Pathologies of Bovine Viral Diarrhea Virus Infection: A Window on the Pathogenesis	2016-01-06		.txt	text/plain	9006	442	40	Pathologic lesions caused by bovine viral diarrhea virus (BVDV) infections comprise a wide spectrum of type, degree, and, by implication, pathogenesis, including congenital defects, necrotic-erosive lesions in mucosal epithelia and skin, and reactive as well as degenerative changes in lymphoid tissues. 3, 22, 29 In PI calves, BVDV can be isolated from lung tissue, and virus antigen is widespread in bronchiolar and alveolar epithelial cells, however, without accompanying histopathologic changes (see section on persistent infection without overt clinical disease and Fig. 5 ).17 Conversely, a proportion (the size varying with study) of cattle succumbing to BRD are positive for BVDV, by virus isolation from or antigen detection in lung tissue, but the ensuing pathologic changes cannot be distinguished from those of other viral pathogens in the BRD complex (perhaps with the exception of BHV-P5), and usually are dominated by the pathology caused by the secondary bacterial agent.	./cache/cord-007362-pjpkz6wv.txt	./txt/cord-007362-pjpkz6wv.txt