id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-005007-pofm8b5x	Higgins, P. G.	Interferons and viral infections	1984		.txt	text/plain	1595	98	35	This has been shown to occur in some children who are abnormally susceptible to upper respiratory tract infections (2) and also in some instances of fulminating hepatitis, when giving exogenous interferon appears to activate the patient's own interferon production (3). As interferon's antiviral effect is mediated through the protection of non-infected cells and not by any direct action on the virus particle, interferon's prophylactic effect will probably be greater than its therapeutic action. For example it is now known that there is a critical concentration of interferon and frequency of administration below which intranasal interferon fails to protect against experimental rhinovirus infection (26) and that the beneficial effect of interferon in zoster in patients with malignancies is directly related to the amount given (16, 27) . Effect of human leukocyte interferon on hepatitis B virus infection in patients with chxonic active hepatitis	./cache/cord-005007-pofm8b5x.txt	./txt/cord-005007-pofm8b5x.txt