id author title date pages extension mime words sentences flesch summary cache txt cord-003425-c5jdp5jv Fu, Yangxi Human adenovirus type 7 infection causes a more severe disease than type 3 2019-01-09 .txt text/plain 5640 334 45 RESULTS: Clinical characteristics revealed that HAdV-7 infection caused more severe pneumonia, toxic encephalopathy, respiratory failure, longer mean hospitalization, significantly lower white blood cell (WBC) and platelet counts, compared to those of HAdV-3. In the present study, therefore, we undertook a comprehensive analysis of the comparative clinical features of HAdV-3 and HAdV-7 infection, as well as a serial of experiments, were performed to better understand the association between severity of the disease and the serotypes of HAdVs. Participants, demographic data, clinical data analysis Patients ranging in age from 1 month to 16 years and requiring inpatient treatment due to acute respiratory tract infections (ARTI) at the Department of Respiratory Medicine, Children's Hospital of Chongqing Medical University between June, 2009 and May, 2015, were enrolled in this study. Since type-specific adenovirus infection is known to cause different tissue tropisms and clinical manifestations as indicated before, viral loads and fitness of HAdV-3 and HAdV-7 were evaluated in several human epithelial cells to determine if there were differences. ./cache/cord-003425-c5jdp5jv.txt ./txt/cord-003425-c5jdp5jv.txt