Carrel name: keyword-infant-cord Creating study carrel named keyword-infant-cord Initializing database file: cache/cord-007036-gcdn13yc.json key: cord-007036-gcdn13yc authors: Nevez, Gilles; Guillaud-Saumur, Thibaud; Cros, Pierrick; Papon, Nicolas; Vallet, Sophie; Quinio, Dorothée; Minoui-Tran, Adissa; Pilorgé, Léa; de Parscau, Loïc; Sizun, Jacques; Ochoa, Theresa J; Bustamante, Beatriz; Ponce, Carolina; Vargas, Sergio L; Le Gal, Solène title: Pneumocystis primary infection in infancy: Additional French data and review of the literature date: 2019-05-25 journal: Med Mycol DOI: 10.1093/mmy/myz040 sha: doc_id: 7036 cord_uid: gcdn13yc file: cache/cord-007528-no92pmw0.json key: cord-007528-no92pmw0 authors: Pineda, Roberta; Prince, Danielle; Reynolds, Jenny; Grabill, Molly; Smith, Joan title: Preterm infant feeding performance at term equivalent age differs from that of full-term infants date: 2020-02-17 journal: J Perinatol DOI: 10.1038/s41372-020-0616-2 sha: doc_id: 7528 cord_uid: no92pmw0 file: cache/cord-010863-m36kxc4x.json key: cord-010863-m36kxc4x authors: Croop, Sarah E. W.; Thoyre, Suzanne M.; Aliaga, Sofia; McCaffrey, Martin J.; Peter-Wohl, Sigal title: The Golden Hour: a quality improvement initiative for extremely premature infants in the neonatal intensive care unit date: 2019-11-11 journal: J Perinatol DOI: 10.1038/s41372-019-0545-0 sha: doc_id: 10863 cord_uid: m36kxc4x file: cache/cord-015172-hya08ch9.json key: cord-015172-hya08ch9 authors: nan title: Abstracts der 41. Jahrestagung der Gesellschaft für Neonatologie und Pädiatrische Intensivmedizin date: 2015-05-20 journal: Monatsschr Kinderheilkd DOI: 10.1007/s00112-015-3359-y sha: doc_id: 15172 cord_uid: hya08ch9 file: cache/cord-018398-24pkhgn8.json key: cord-018398-24pkhgn8 authors: O'Riordan, Declan; Porcelli, Peter J. title: Neonatal Care and Data date: 2009 journal: Pediatric Informatics DOI: 10.1007/978-0-387-76446-7_4 sha: doc_id: 18398 cord_uid: 24pkhgn8 file: cache/cord-000285-7p3b6tyf.json key: cord-000285-7p3b6tyf authors: HARTERT, Tina V.; CARROLL, Kecia; GEBRETSADIK, Tebeb; WOODWARD, Kimberly; MINTON, Patricia title: The Tennessee Children's Respiratory Initiative: Objectives, design and recruitment results of a prospective cohort study investigating infant viral respiratory illness and the development of asthma and allergic diseases date: 2010-04-08 journal: Respirology DOI: 10.1111/j.1440-1843.2010.01743.x sha: doc_id: 285 cord_uid: 7p3b6tyf file: cache/cord-014673-bb59z38j.json key: cord-014673-bb59z38j authors: nan title: Abstracts 2019 der GNPI und DGPI: 45. Jahrestagung der Gesellschaft für Neonatologie und Pädiatrische Intensivmedizin gemeinsam mit der 27. Jahrestagung der Deutschen Gesellschaft für Pädiatrische Infektiologie, 23.–25. Mai 2019, Leipzig date: 2019-05-20 journal: Monatsschr Kinderheilkd DOI: 10.1007/s00112-019-0700-x sha: doc_id: 14673 cord_uid: bb59z38j file: cache/cord-279257-a7d9a2w1.json key: cord-279257-a7d9a2w1 authors: Puig, Carme; Sunyer, Jordi; Garcia‐Algar, Oscar; Muñoz, Laura; Pacifici, Roberta; Pichini, Simona; Vall, Oriol title: Incidence and risk factors of lower respiratory tract illnesses during infancy in a Mediterranean birth cohort date: 2008-07-09 journal: Acta Paediatr DOI: 10.1111/j.1651-2227.2008.00939.x sha: doc_id: 279257 cord_uid: a7d9a2w1 file: cache/cord-323354-igzs1rdm.json key: cord-323354-igzs1rdm authors: Dornelles, Cristina T.L.; Piva, Jefferson P.; Marostica, Paulo J.C. title: Nutritional Status, Breastfeeding, and Evolution of Infants with Acute Viral Bronchiolitis date: 2007-09-17 journal: J Health Popul Nutr DOI: nan sha: doc_id: 323354 cord_uid: igzs1rdm file: cache/cord-021571-7kbq0v9w.json key: cord-021571-7kbq0v9w authors: Heath, Joan A.; Zerr, Danielle M. title: Infections Acquired in the Nursery: Epidemiology and Control date: 2009-05-19 journal: Infectious Diseases of the Fetus and Newborn Infant DOI: 10.1016/b0-72-160537-0/50037-2 sha: doc_id: 21571 cord_uid: 7kbq0v9w file: cache/cord-005774-7z6uyn6p.json key: cord-005774-7z6uyn6p authors: Hammer, J.; Newth, C. J. L. title: Infant lung function testing in the intensive care unit date: 1995 journal: Intensive Care Med DOI: 10.1007/bf01704742 sha: doc_id: 5774 cord_uid: 7z6uyn6p file: cache/cord-023721-e0zp2gux.json key: cord-023721-e0zp2gux authors: Meissner, H. Cody title: Bronchiolitis date: 2013-02-10 journal: Principles and Practice of Pediatric Infectious Diseases DOI: 10.1016/b978-1-4377-2702-9.00033-7 sha: doc_id: 23721 cord_uid: e0zp2gux file: cache/cord-258778-er0ug8w4.json key: cord-258778-er0ug8w4 authors: Maayan-Metzger, Ayala; Itzchak, Amir; Mazkereth, Ram; Kuint, Jacob title: Necrotizing Enterocolitis in Full-Term Infants: Case–Control Study and Review of the Literature date: 2004-07-01 journal: J Perinatol DOI: 10.1038/sj.jp.7211135 sha: doc_id: 258778 cord_uid: er0ug8w4 file: cache/cord-286479-p9d78t6v.json key: cord-286479-p9d78t6v authors: nan title: NeoCORE Conference Abstracts date: 2020-07-09 journal: Indian J Pediatr DOI: 10.1007/s12098-020-03376-y sha: doc_id: 286479 cord_uid: p9d78t6v file: cache/cord-010848-090yk40o.json key: cord-010848-090yk40o authors: Wang, Yan; Zhu, Wei; Luo, Bi-ru title: Continuous feeding versus intermittent bolus feeding for premature infants with low birth weight: a meta-analysis of randomized controlled trials date: 2019-10-28 journal: Eur J Clin Nutr DOI: 10.1038/s41430-019-0522-x sha: doc_id: 10848 cord_uid: 090yk40o file: cache/cord-303322-d69o3z8d.json key: cord-303322-d69o3z8d authors: Chang, Anne B; Grimwood, Keith; White, Andrew V; Maclennan, Carolyn; Sloots, Theo P; Sive, Alan; McCallum, Gabrielle B; Mackay, Ian M; Morris, Peter S title: Randomized placebo-controlled trial on azithromycin to reduce the morbidity of bronchiolitis in Indigenous Australian infants: rationale and protocol date: 2011-04-14 journal: Trials DOI: 10.1186/1745-6215-12-94 sha: doc_id: 303322 cord_uid: d69o3z8d file: cache/cord-018604-ua5h47jg.json key: cord-018604-ua5h47jg authors: Dersch-Mills, Deonne title: Assessment Considerations in Pediatric Patients date: 2018-12-28 journal: Patient Assessment in Clinical Pharmacy DOI: 10.1007/978-3-030-11775-7_28 sha: doc_id: 18604 cord_uid: ua5h47jg file: cache/cord-337878-hiylqqie.json key: cord-337878-hiylqqie authors: Namasivayam, Abirami; Soe, Than; Palman, Jason title: Atypical case of COVID-19 in a critically unwell 5-week old infant date: 2020-09-14 journal: BMJ Case Rep DOI: 10.1136/bcr-2020-237142 sha: doc_id: 337878 cord_uid: hiylqqie file: cache/cord-008165-qwyddp69.json key: cord-008165-qwyddp69 authors: Candy, David C.A.; Devane, Seán P. title: Role of micro-organisms in necrotizing enterocolitis date: 2006-12-24 journal: Semin Neonatol DOI: 10.1016/s1084-2756(97)80032-2 sha: doc_id: 8165 cord_uid: qwyddp69 file: cache/cord-004657-kmluql8h.json key: cord-004657-kmluql8h authors: Eibl, Martha M.; Wolf, Hermann M.; Fürnkranz, Heinz; Rosenkranz, Alfred title: Prophylaxis of necrotizing enterocolitis by oral IgA-IgG: Review of a clinical study in low birth weight infants and discussion of the pathogenic role of infection date: 1990 journal: J Clin Immunol DOI: 10.1007/bf00918694 sha: doc_id: 4657 cord_uid: kmluql8h file: cache/cord-010818-yz0gynn0.json key: cord-010818-yz0gynn0 authors: Soliman, Yasser; Alshaikh, Belal; Alawad, Essa; Akierman, Albert; Elsharkawy, Adel; Yusuf, Kamran title: Respiratory outcomes of late preterm infants of mothers with early and late onset preeclampsia date: 2019-09-24 journal: J Perinatol DOI: 10.1038/s41372-019-0497-4 sha: doc_id: 10818 cord_uid: yz0gynn0 file: cache/cord-022544-7jn4ns6x.json key: cord-022544-7jn4ns6x authors: Lawrence, Robert M. title: Host-Resistance Factors and Immunologic Significance of Human Milk date: 2010-12-27 journal: Breastfeeding DOI: 10.1016/b978-1-4377-0788-5.10005-7 sha: doc_id: 22544 cord_uid: 7jn4ns6x file: cache/cord-011257-d12cj9v5.json key: cord-011257-d12cj9v5 authors: McEvoy, Cindy T.; Ballard, Philip L.; Ward, Robert M.; Rower, Joseph E.; Wadhawan, Rajan; Hudak, Mark L.; Weitkamp, Joern-Hendrik; Harris, Julia; Asselin, Jeanette; Chapin, Cheryl; Ballard, Roberta A. title: Dose-escalation trial of budesonide in surfactant for prevention of bronchopulmonary dysplasia in extremely low gestational age high-risk newborns (SASSIE) date: 2020-02-01 journal: Pediatr Res DOI: 10.1038/s41390-020-0792-y sha: doc_id: 11257 cord_uid: d12cj9v5 file: cache/cord-009144-3slh1nbk.json key: cord-009144-3slh1nbk authors: Jacobs, J.W.; Peacock, D.B.; Corner, B.D.; Caul, E.O.; Clarke, S.K.R. title: RESPIRATORY SYNCYTIAL AND OTHER VIRUSES ASSOCIATED WITH RESPIRATORY DISEASE IN INFANTS date: 1971-05-01 journal: Lancet DOI: 10.1016/s0140-6736(71)92440-8 sha: doc_id: 9144 cord_uid: 3slh1nbk file: cache/cord-016241-qom2rokn.json key: cord-016241-qom2rokn authors: Chen, Long; Li, Jie; Wang, Nan; Shi, Yuan title: Post-Newborn: A New Concept of Period in Early Life date: 2013-12-06 journal: Frontier and Future Development of Information Technology in Medicine and Education DOI: 10.1007/978-94-007-7618-0_143 sha: doc_id: 16241 cord_uid: qom2rokn file: cache/cord-265366-vmuqbpkk.json key: cord-265366-vmuqbpkk authors: Leibowitz, Jill; Krief, William; Barone, Stephen; Williamson, Kristy A.; Goenka, Pratichi K.; Rai, Shipra; Moriarty, Shannon; Baodhankar, Prachi; Rubin, Lorry G. title: Comparison of Clinical and Epidemiologic Characteristics of Young Febrile Infants with and without SARS-CoV-2 Infection date: 2020-10-09 journal: J Pediatr DOI: 10.1016/j.jpeds.2020.10.002 sha: doc_id: 265366 cord_uid: vmuqbpkk file: cache/cord-269652-t7ghng17.json key: cord-269652-t7ghng17 authors: Santos, Roberto Parulan; Tristram, Debra title: A Practical Guide to the Diagnosis, Treatment, and Prevention of Neonatal Infections date: 2015-04-30 journal: Pediatric Clinics of North America DOI: 10.1016/j.pcl.2014.11.010 sha: doc_id: 269652 cord_uid: t7ghng17 file: cache/cord-338575-c04xxo8d.json key: cord-338575-c04xxo8d authors: Stuebe, Alison title: Should Infants Be Separated from Mothers with COVID-19? First, Do No Harm date: 2020-05-01 journal: Breastfeed Med DOI: 10.1089/bfm.2020.29153.ams sha: doc_id: 338575 cord_uid: c04xxo8d file: cache/cord-014951-2931ep31.json key: cord-014951-2931ep31 authors: El Basha, Noussa R.; Marzouk, Huda; Sherif, May M.; El Kholy, Amani A. title: Prematurity, a significant predictor for worse outcome in viral bronchiolitis: a comparative study in infancy date: 2019-03-22 journal: J Egypt Public Health Assoc DOI: 10.1186/s42506-019-0015-8 sha: doc_id: 14951 cord_uid: 2931ep31 file: cache/cord-266373-8wuvk5cz.json key: cord-266373-8wuvk5cz authors: Burns, Katherine H.; Saunders, Barbara S.; Burns, Samuel A. title: Nurturing visual social development in the NICU date: 2020-09-05 journal: J Perinatol DOI: 10.1038/s41372-020-00813-w sha: doc_id: 266373 cord_uid: 8wuvk5cz file: cache/cord-296114-cyd9msls.json key: cord-296114-cyd9msls authors: Mallol, J.; Aguirre, V.; Wandalsen, G. title: Common cold decreases lung function in infants with recurrent wheezing date: 2009-11-27 journal: Allergol Immunopathol (Madr) DOI: 10.1016/j.aller.2009.10.001 sha: doc_id: 296114 cord_uid: cyd9msls file: cache/cord-022216-k4pi30sd.json key: cord-022216-k4pi30sd authors: Kliegman, Robert M. title: Neonatal necrotizing enterocolitis date: 2009-05-15 journal: Pediatric Gastrointestinal and Liver Disease DOI: 10.1016/b978-0-7216-3924-6.50047-0 sha: doc_id: 22216 cord_uid: k4pi30sd file: cache/cord-011688-8g0p3vtm.json key: cord-011688-8g0p3vtm authors: Wang, Ting-Ting; Zhou, Ming; Hu, Xue-Feng; Liu, Jiang-Qin title: Perinatal risk factors for pulmonary hemorrhage in extremely low-birth-weight infants date: 2019-11-04 journal: World J Pediatr DOI: 10.1007/s12519-019-00322-7 sha: doc_id: 11688 cord_uid: 8g0p3vtm file: cache/cord-023942-vrs3je1x.json key: cord-023942-vrs3je1x authors: Powers, Karen S. title: Acute Pulmonary Infections date: 2011-12-16 journal: Pediatric Critical Care Study Guide DOI: 10.1007/978-0-85729-923-9_25 sha: doc_id: 23942 cord_uid: vrs3je1x file: cache/cord-032806-o6p861ms.json key: cord-032806-o6p861ms authors: Fenin, Audrey; Newman, Jill C.; Taylor, Sarah N. title: Very low birth weight infants receive full enteral nutrition within 2 postnatal weeks date: 2020-09-29 journal: J Perinatol DOI: 10.1038/s41372-020-00819-4 sha: doc_id: 32806 cord_uid: o6p861ms file: cache/cord-314190-fvdock94.json key: cord-314190-fvdock94 authors: Florin, Todd A; Plint, Amy C; Zorc, Joseph J title: Viral bronchiolitis date: 2017-01-01 journal: The Lancet DOI: 10.1016/s0140-6736(16)30951-5 sha: doc_id: 314190 cord_uid: fvdock94 file: cache/cord-329022-0pymqxwq.json key: cord-329022-0pymqxwq authors: Hughes, Michelle M; Englund, Janet A; Kuypers, Jane; Tielsch, James M; Khatry, Subarna K; Shrestha, Laxman; LeClerq, Steven C; Steinhoff, Mark; Katz, Joanne title: Population-Based Pertussis Incidence and Risk Factors in Infants Less Than 6 Months in Nepal date: 2017-03-01 journal: J Pediatric Infect Dis Soc DOI: 10.1093/jpids/piw079 sha: doc_id: 329022 cord_uid: 0pymqxwq file: cache/cord-288113-ex4yi28u.json key: cord-288113-ex4yi28u authors: Epalza, Cristina; Hallin, Marie; Busson, Laurent; Debulpaep, Sara; De Backer, Paulette; Vandenberg, Olivier; Levy, Jack title: Role of Viral Molecular Panels in Diagnosing the Etiology of Fever in Infants Younger Than 3 Months date: 2019-11-09 journal: Clin Pediatr (Phila) DOI: 10.1177/0009922819884582 sha: doc_id: 288113 cord_uid: ex4yi28u file: cache/cord-355292-n6sq2jz9.json key: cord-355292-n6sq2jz9 authors: Chen, Yan; Peng, Hua; Wang, Lin; Zhao, Yin; Zeng, Lingkong; Gao, Hui; Liu, Yalan title: Infants Born to Mothers With a New Coronavirus (COVID-19) date: 2020-03-16 journal: Front Pediatr DOI: 10.3389/fped.2020.00104 sha: doc_id: 355292 cord_uid: n6sq2jz9 file: cache/cord-253520-phtmgy6g.json key: cord-253520-phtmgy6g authors: nan title: Vaccination schedule for infants and COVID-19 date: 2020-05-23 journal: Bull Acad Natl Med DOI: 10.1016/j.banm.2020.05.078 sha: doc_id: 253520 cord_uid: phtmgy6g file: cache/cord-332113-37g4regv.json key: cord-332113-37g4regv authors: Neu, Josef title: The Microbiome and Its Impact on Disease in the Preterm Patient date: 2013-10-01 journal: Current Pediatrics Reports DOI: 10.1007/s40124-013-0031-7 sha: doc_id: 332113 cord_uid: 37g4regv file: cache/cord-346214-8ev9w4ko.json key: cord-346214-8ev9w4ko authors: Unger, Sharon; Stintzi, Alain; Shah, Prakeshkumar; Mack, David; O'Connor, Deborah L title: Gut microbiota of the very-low-birth-weight infant date: 2014-10-13 journal: Pediatr Res DOI: 10.1038/pr.2014.162 sha: doc_id: 346214 cord_uid: 8ev9w4ko file: cache/cord-330834-zqm4egei.json key: cord-330834-zqm4egei authors: Drall, Kelsea M.; Field, Catherine J.; Haqq, Andrea M.; de Souza, Russell J.; Tun, Hein M.; Morales-Lizcano, Nadia P.; Konya, Theodore B.; Guttman, David S.; Azad, Meghan B.; Becker, Allan B.; Lefebvre, Diana L.; Mandhane, Piush J.; Moraes, Theo J.; Sears, Malcolm R.; Turvey, Stuart E.; Subbarao, Padmaja; Scott, James A.; Kozyrskyj, Anita L title: Vitamin D supplementation in pregnancy and early infancy in relation to gut microbiota composition and C. difficile colonization: implications for viral respiratory infections date: 2020-08-11 journal: Gut microbes DOI: 10.1080/19490976.2020.1799734 sha: doc_id: 330834 cord_uid: zqm4egei file: cache/cord-022592-g7rmzsv5.json key: cord-022592-g7rmzsv5 authors: Wynn, James L.; Wong, Hector R. title: Pathophysiology of Neonatal Sepsis date: 2016-07-06 journal: Fetal and Neonatal Physiology DOI: 10.1016/b978-0-323-35214-7.00152-9 sha: doc_id: 22592 cord_uid: g7rmzsv5 file: cache/cord-022448-ungitgh9.json key: cord-022448-ungitgh9 authors: Sergueef, Nicette title: Clinical Conditions date: 2009-05-15 journal: Cranial Osteopathy for Infants, Children and Adolescents DOI: 10.1016/b978-0-443-10352-0.50013-4 sha: doc_id: 22448 cord_uid: ungitgh9 file: cache/cord-305085-bv7udg9k.json key: cord-305085-bv7udg9k authors: Lawrence, Robert M. title: Chapter 13 Transmission of Infectious Diseases Through Breast Milk and Breastfeeding date: 2011-12-31 journal: Breastfeeding DOI: 10.1016/b978-1-4377-0788-5.10013-6 sha: doc_id: 305085 cord_uid: bv7udg9k file: cache/cord-023767-rcv4pl0d.json key: cord-023767-rcv4pl0d authors: O’Ryan, Miguel L.; Nataro, James P.; Cleary, Thomas G. title: Microorganisms Responsible for Neonatal Diarrhea date: 2009-05-19 journal: Infectious Diseases of the Fetus and Newborn Infant DOI: 10.1016/b0-72-160537-0/50022-0 sha: doc_id: 23767 cord_uid: rcv4pl0d file: cache/cord-005646-xhx9pzhj.json key: cord-005646-xhx9pzhj authors: nan title: 2nd World Congress on Pediatric Intensive Care 1996 Rotterdam, The Netherlands, 23–26 June 1996 Abstracts of Oral Presentations, Posters and Nursing Programme date: 1996 journal: Intensive Care Med DOI: 10.1007/bf02316512 sha: doc_id: 5646 cord_uid: xhx9pzhj Reading metadata file and updating bibliogrpahics === updating bibliographic database Building study carrel named keyword-infant-cord parallel: Warning: No more processes: Decreasing number of running jobs to 47. parallel: Warning: Raising ulimit -u or /etc/security/limits.conf may help. parallel: Warning: No more processes: Decreasing number of running jobs to 46. parallel: Warning: Raising ulimit -u or /etc/security/limits.conf may help. /data-disk/reader-compute/reader-cord/bin/cordent2carrel.sh: fork: retry: No child processes /data-disk/reader-compute/reader-cord/bin/cordwrd2carrel.sh: fork: retry: No child processes /data-disk/reader-compute/reader-cord/bin/txt2urls.sh: fork: retry: No child processes /data-disk/reader-compute/reader-cord/bin/cordwrd2carrel.sh: fork: retry: No child processes === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 41643 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 41629 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 41630 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 41915 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 43328 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 41926 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 41870 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 43489 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 45092 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 44303 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 42674 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 47335 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 46264 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 45274 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 43546 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 43777 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 46326 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 46263 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 47304 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 47356 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 48574 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 47357 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 47582 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 47714 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 46994 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 47491 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 46951 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 48352 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 47584 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === OMP: Error #34: System unable to allocate necessary resources for OMP thread: OMP: System error #11: Resource temporarily unavailable OMP: Hint Try decreasing the value of OMP_NUM_THREADS. /data-disk/reader-compute/reader-cord/bin/file2bib.sh: line 39: 46919 Aborted $FILE2BIB "$FILE" > "$OUTPUT" === file2bib.sh === id: cord-253520-phtmgy6g author: nan title: Vaccination schedule for infants and COVID-19 date: 2020-05-23 pages: extension: .txt txt: ./txt/cord-253520-phtmgy6g.txt cache: ./cache/cord-253520-phtmgy6g.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 2 resourceName b'cord-253520-phtmgy6g.txt' === file2bib.sh === id: cord-355292-n6sq2jz9 author: Chen, Yan title: Infants Born to Mothers With a New Coronavirus (COVID-19) date: 2020-03-16 pages: extension: .txt txt: ./txt/cord-355292-n6sq2jz9.txt cache: ./cache/cord-355292-n6sq2jz9.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 3 resourceName b'cord-355292-n6sq2jz9.txt' === file2bib.sh === id: cord-258778-er0ug8w4 author: Maayan-Metzger, Ayala title: Necrotizing Enterocolitis in Full-Term Infants: Case–Control Study and Review of the Literature date: 2004-07-01 pages: extension: .txt txt: ./txt/cord-258778-er0ug8w4.txt cache: ./cache/cord-258778-er0ug8w4.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 4 resourceName b'cord-258778-er0ug8w4.txt' === file2bib.sh === id: cord-337878-hiylqqie author: Namasivayam, Abirami title: Atypical case of COVID-19 in a critically unwell 5-week old infant date: 2020-09-14 pages: extension: .txt txt: ./txt/cord-337878-hiylqqie.txt cache: ./cache/cord-337878-hiylqqie.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 4 resourceName b'cord-337878-hiylqqie.txt' === file2bib.sh === id: cord-010818-yz0gynn0 author: Soliman, Yasser title: Respiratory outcomes of late preterm infants of mothers with early and late onset preeclampsia date: 2019-09-24 pages: extension: .txt txt: ./txt/cord-010818-yz0gynn0.txt cache: ./cache/cord-010818-yz0gynn0.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 4 resourceName b'cord-010818-yz0gynn0.txt' === file2bib.sh === id: cord-303322-d69o3z8d author: Chang, Anne B title: Randomized placebo-controlled trial on azithromycin to reduce the morbidity of bronchiolitis in Indigenous Australian infants: rationale and protocol date: 2011-04-14 pages: extension: .txt txt: ./txt/cord-303322-d69o3z8d.txt cache: ./cache/cord-303322-d69o3z8d.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 4 resourceName b'cord-303322-d69o3z8d.txt' === file2bib.sh === /data-disk/reader-compute/reader-cord/bin/file2bib.sh: fork: retry: No child processes id: cord-332113-37g4regv author: Neu, Josef title: The Microbiome and Its Impact on Disease in the Preterm Patient date: 2013-10-01 pages: extension: .txt txt: ./txt/cord-332113-37g4regv.txt cache: ./cache/cord-332113-37g4regv.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 3 resourceName b'cord-332113-37g4regv.txt' === file2bib.sh === /data-disk/reader-compute/reader-cord/bin/file2bib.sh: fork: retry: No child processes id: cord-346214-8ev9w4ko author: Unger, Sharon title: Gut microbiota of the very-low-birth-weight infant date: 2014-10-13 pages: extension: .txt txt: ./txt/cord-346214-8ev9w4ko.txt cache: ./cache/cord-346214-8ev9w4ko.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 4 resourceName b'cord-346214-8ev9w4ko.txt' === file2bib.sh === id: cord-018604-ua5h47jg author: Dersch-Mills, Deonne title: Assessment Considerations in Pediatric Patients date: 2018-12-28 pages: extension: .txt txt: ./txt/cord-018604-ua5h47jg.txt cache: ./cache/cord-018604-ua5h47jg.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 3 resourceName b'cord-018604-ua5h47jg.txt' === file2bib.sh === id: cord-023942-vrs3je1x author: Powers, Karen S. title: Acute Pulmonary Infections date: 2011-12-16 pages: extension: .txt txt: ./txt/cord-023942-vrs3je1x.txt cache: ./cache/cord-023942-vrs3je1x.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 4 resourceName b'cord-023942-vrs3je1x.txt' === file2bib.sh === id: cord-014673-bb59z38j author: nan title: Abstracts 2019 der GNPI und DGPI: 45. Jahrestagung der Gesellschaft für Neonatologie und Pädiatrische Intensivmedizin gemeinsam mit der 27. Jahrestagung der Deutschen Gesellschaft für Pädiatrische Infektiologie, 23.–25. Mai 2019, Leipzig date: 2019-05-20 pages: extension: .txt txt: ./txt/cord-014673-bb59z38j.txt cache: ./cache/cord-014673-bb59z38j.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 3 resourceName b'cord-014673-bb59z38j.txt' === file2bib.sh === id: cord-021571-7kbq0v9w author: Heath, Joan A. title: Infections Acquired in the Nursery: Epidemiology and Control date: 2009-05-19 pages: extension: .txt txt: ./txt/cord-021571-7kbq0v9w.txt cache: ./cache/cord-021571-7kbq0v9w.txt Content-Encoding ISO-8859-1 Content-Type text/plain; charset=ISO-8859-1 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 3 resourceName b'cord-021571-7kbq0v9w.txt' === file2bib.sh === id: cord-022544-7jn4ns6x author: Lawrence, Robert M. title: Host-Resistance Factors and Immunologic Significance of Human Milk date: 2010-12-27 pages: extension: .txt txt: ./txt/cord-022544-7jn4ns6x.txt cache: ./cache/cord-022544-7jn4ns6x.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 3 resourceName b'cord-022544-7jn4ns6x.txt' === file2bib.sh === id: cord-022592-g7rmzsv5 author: Wynn, James L. title: Pathophysiology of Neonatal Sepsis date: 2016-07-06 pages: extension: .txt txt: ./txt/cord-022592-g7rmzsv5.txt cache: ./cache/cord-022592-g7rmzsv5.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 4 resourceName b'cord-022592-g7rmzsv5.txt' === file2bib.sh === /data-disk/reader-compute/reader-cord/bin/file2bib.sh: fork: retry: No child processes id: cord-023767-rcv4pl0d author: O’Ryan, Miguel L. title: Microorganisms Responsible for Neonatal Diarrhea date: 2009-05-19 pages: extension: .txt txt: ./txt/cord-023767-rcv4pl0d.txt cache: ./cache/cord-023767-rcv4pl0d.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 4 resourceName b'cord-023767-rcv4pl0d.txt' === file2bib.sh === id: cord-305085-bv7udg9k author: Lawrence, Robert M. title: Chapter 13 Transmission of Infectious Diseases Through Breast Milk and Breastfeeding date: 2011-12-31 pages: extension: .txt txt: ./txt/cord-305085-bv7udg9k.txt cache: ./cache/cord-305085-bv7udg9k.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 6 resourceName b'cord-305085-bv7udg9k.txt' === file2bib.sh === id: cord-005646-xhx9pzhj author: nan title: 2nd World Congress on Pediatric Intensive Care 1996 Rotterdam, The Netherlands, 23–26 June 1996 Abstracts of Oral Presentations, Posters and Nursing Programme date: 1996 pages: extension: .txt txt: ./txt/cord-005646-xhx9pzhj.txt cache: ./cache/cord-005646-xhx9pzhj.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 5 resourceName b'cord-005646-xhx9pzhj.txt' === file2bib.sh === id: cord-022448-ungitgh9 author: Sergueef, Nicette title: Clinical Conditions date: 2009-05-15 pages: extension: .txt txt: ./txt/cord-022448-ungitgh9.txt cache: ./cache/cord-022448-ungitgh9.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 X-Parsed-By ['org.apache.tika.parser.DefaultParser', 'org.apache.tika.parser.csv.TextAndCSVParser'] X-TIKA:content_handler ToTextContentHandler X-TIKA:embedded_depth 0 X-TIKA:parse_time_millis 7 resourceName b'cord-022448-ungitgh9.txt' Que is empty; done keyword-infant-cord === reduce.pl bib === === reduce.pl bib === === reduce.pl bib === === reduce.pl bib === === reduce.pl bib === === reduce.pl bib === === reduce.pl bib === id = cord-014673-bb59z38j author = nan title = Abstracts 2019 der GNPI und DGPI: 45. Jahrestagung der Gesellschaft für Neonatologie und Pädiatrische Intensivmedizin gemeinsam mit der 27. Jahrestagung der Deutschen Gesellschaft für Pädiatrische Infektiologie, 23.–25. Mai 2019, Leipzig date = 2019-05-20 pages = extension = .txt mime = text/plain words = 14190 sentences = 1420 flesch = 50 summary = Schlussfolgerung: Die aktuelle Studie zeigt, dass die Zebrafischlarve unter Zuhilfenahme innovativer mikroskopischer Technologien ein gutes Tier-Im Rahmen der europäischen ALBINO Studie wird die neuroprotektive Wirkung von Allopurinol bei Neugeborenen mit schwerer perinataler Aspyhxie zusätzlich zur Hypothermiebehandlung geprüft. They provide daily reference weights from birth to 42 weeks of postmenstrual age (PMA) Objective: The study aims to: 1) compare observed deviations of weight (∆W) from the GTC trajectory between cohorts and 2) analyze relationships between ∆W and short-term outcomes. Design/Methods: International multicohort study, including infants with a gestational age (GA) from 22 to 33 weeks with weekly or daily weight data from eight local cohorts (Austria, Germany, Sweden, Australia, Canada, USA) and the German Neonatal Network (birth weight (BW), 35 weeks PMA, discharge) during 2001 to 2017. Ein Säugling mit 3500 g und einer Compliance von 1,0 ml/mbar muss für 6 Background: We report on the latest progress made in the development of a lung assist device in the artificial placenta configuration. cache = ./cache/cord-014673-bb59z38j.txt txt = ./txt/cord-014673-bb59z38j.txt === reduce.pl bib === === reduce.pl bib === id = cord-021571-7kbq0v9w author = Heath, Joan A. title = Infections Acquired in the Nursery: Epidemiology and Control date = 2009-05-19 pages = extension = .txt mime = text/plain words = 21244 sentences = 1014 flesch = 41 summary = The fact that a hand hygiene campaign was associated with increased hand hygiene compliance and a lower rate of CONS-positive cultures supports this ~ontention.'~ Enterococcus has been shown to account for 10% of total nosocomial infections in neonates, 6% to 15% of bloodstream infections, 0% to 5% of cases of pneumonia, 17% of urinary tract infections, and 9% of surgical site Sepsis and meningitis are common manifestations of enterococcal infection during NICU outbreak^'^,^^; however, polymicrobial bacteremia and NEC frequently accompany enterococcal sepsis.77 Identified risk factors for enterococcal sepsis, after adjustment for birth weight, include use of a nonumbilical CVC, prolonged presence of a CVC, and bowel resection?' Because Enterococcus colonizes the gastrointestinal tract and can survive for long periods of time on inanimate surfaces, the patient's environment may become contaminated and, along with the infant, serve as a reservoir for ongoing spread of the organism. cache = ./cache/cord-021571-7kbq0v9w.txt txt = ./txt/cord-021571-7kbq0v9w.txt === reduce.pl bib === === reduce.pl bib === === reduce.pl bib === === reduce.pl bib === id = cord-258778-er0ug8w4 author = Maayan-Metzger, Ayala title = Necrotizing Enterocolitis in Full-Term Infants: Case–Control Study and Review of the Literature date = 2004-07-01 pages = extension = .txt mime = text/plain words = 3267 sentences = 176 flesch = 51 summary = OBJECTIVE: To examine the increasing number of full-term infants at our hospital exhibiting necrotizing enterocolitis (NEC) in order to characterize these cases and to discover common risk factors. METHODS: Medical charts were reviewed for all full-term infants (gestational age > 36 weeks) that were born in our institution during a 5-year period (from January 1, 1998 to December 31, 2002) and that developed definite NEC. NEC in full-term infants is well documented, accounting for about 10% of babies with NEC; it usually involves babies with known risk factors, such as intrauterine growth retardation (IUGR), birth asphyxia, congenital heart disease, gastroschisis, polycythemia, hypoglycemia, sepsis, exchange transfusion, umbilical lines, milk allergy, premature rupture of membranes with and without chorioamnionitis and gestational diabetes. The findings of the current study show that only half of these full-term infants with NEC exhibited known predisposing risk factors, including congenital heart disease, undiagnosed syndrome, birth asphyxia, intrauterine growth retardation and congenital hypothyroidism. cache = ./cache/cord-258778-er0ug8w4.txt txt = ./txt/cord-258778-er0ug8w4.txt === reduce.pl bib === === reduce.pl bib === === reduce.pl bib === id = cord-303322-d69o3z8d author = Chang, Anne B title = Randomized placebo-controlled trial on azithromycin to reduce the morbidity of bronchiolitis in Indigenous Australian infants: rationale and protocol date = 2011-04-14 pages = extension = .txt mime = text/plain words = 5403 sentences = 287 flesch = 37 summary = Our randomised, placebo-controlled trial of azithromycin in Indigenous infants hospitalised with bronchiolitis is designed to determine whether it can reduce short-term (and potentially long-term) morbidity from respiratory illness in Australian Indigenous infants who are at high risk of developing chronic respiratory illness. Indigenous infants (aged ≤ 24-months, expected number = 200) admitted to one of two regional hospitals (Darwin, Northern Territory and Townsville, Queensland) with a clinical diagnosis of bronchiolitis and fulfilling inclusion criteria are randomised (allocation concealed) to either azithromycin (30 mg/kg/dose) or placebo administered once weekly for three doses. Indigenous infants (aged ≤ 24-months, expected number = 200) admitted to one of two regional hospitals (Darwin, Northern Territory and Townsville, Queensland) with a clinical diagnosis of bronchiolitis and fulfilling inclusion criteria are randomised (allocation concealed) to either azithromycin (30 mg/kg/dose) or placebo administered once weekly for three doses. cache = ./cache/cord-303322-d69o3z8d.txt txt = ./txt/cord-303322-d69o3z8d.txt === reduce.pl bib === id = cord-018604-ua5h47jg author = Dersch-Mills, Deonne title = Assessment Considerations in Pediatric Patients date = 2018-12-28 pages = extension = .txt mime = text/plain words = 6368 sentences = 312 flesch = 47 summary = Pharmacists need to be aware of this variability and use every patient encounter as an opportunity for assessment of many aspects of medication including dose, formulation, administration, and indication. Infants and children also have physiological differences that need to be considered especially when assessing efficacy, toxicity, and the patient's overall response to medications through physical exam or use of laboratory values. Lastly, a lack of appropriate medication formulations for children creates a requirement for pharmacists to specifically assess the formulations, measurement, and administration of pediatric medications. Until children are mature enough to provide this information themselves (note that this age varies depending on the child), parents and other caregivers are relied upon to provide an accurate history of the patient's illness(s) and medication(s). Because of the lack of appropriate information in the product labeling, alternative data sources need to be accessed to assess the use of the medication in an infant or child. cache = ./cache/cord-018604-ua5h47jg.txt txt = ./txt/cord-018604-ua5h47jg.txt === reduce.pl bib === id = cord-337878-hiylqqie author = Namasivayam, Abirami title = Atypical case of COVID-19 in a critically unwell 5-week old infant date = 2020-09-14 pages = extension = .txt mime = text/plain words = 2519 sentences = 153 flesch = 49 summary = To our knowledge, he is the youngest reported case in the UK to require mechanical ventilation and intensive care treatment as a direct result of COVID-19 following horizontal transmission. 4 A larger nationwide study investigating 134 paediatric cases across China reported that 76% cases had fever, 64.9% cases presented as acute upper respiratory tract infection, 26.9% as mild pneumonia and 1.5% cases were critical; unfortunately, the specific age groups and comorbidities were not reported. At present there are few reports of paediatric patients requiring intensive care support with confirmed COVID-19. This case demonstrates the need for vigilance in considering COVID-19 infection in infants presenting with less discriminatory symptoms such as lethargy or reduced feeding. Dong et al report a case series of 2135 paediatric patients with confirmed and suspected coronavirus; infants (<1 year) were noted to be particularly vulnerable. cache = ./cache/cord-337878-hiylqqie.txt txt = ./txt/cord-337878-hiylqqie.txt === reduce.pl bib === === reduce.pl bib === === reduce.pl bib === id = cord-010818-yz0gynn0 author = Soliman, Yasser title = Respiratory outcomes of late preterm infants of mothers with early and late onset preeclampsia date = 2019-09-24 pages = extension = .txt mime = text/plain words = 3709 sentences = 207 flesch = 49 summary = OBJECTIVE: To study the effect of early and late onset preeclampsia (EOPE, LOPE, respectively) on outcomes of late preterm infants. The objective of our study was to investigate the effects of early and late onset preeclampsia on the outcomes of late preterm infants, with the primary objective being respiratory outcomes. Late preterm infants born between 34 +0 and 36 +6 gestation to a mother with early onset preeclampsia between January 2014 and July 2015 were included in the study. Gouyon et al., using a large cohort from France, reported higher risk of severe respiratory morbidity, in late preterm infants of mothers with hypertensive disorder of pregnancy [9] . Respiratory morbidity, defined by the need for oxygen, CPAP or mechanical ventilation was higher at each gestational age in infants of hypertensive mothers but reached statistical significance only at 37 weeks. compared outcomes of late preterm infants of mothers with preeclampsia, gestational hypertension and normotensive pregnancies in a large cohort from the Netherlands [25] . cache = ./cache/cord-010818-yz0gynn0.txt txt = ./txt/cord-010818-yz0gynn0.txt === reduce.pl bib === id = cord-022544-7jn4ns6x author = Lawrence, Robert M. title = Host-Resistance Factors and Immunologic Significance of Human Milk date = 2010-12-27 pages = extension = .txt mime = text/plain words = 22268 sentences = 1177 flesch = 45 summary = The immunologically active components of breast milk make up an important aspect of the host defenses of the mammary gland in the mother; at the same time, they complement, supplement, and stimulate the ongoing development of the infant' s immune system. A number of other long-term studies demonstrated greater protection from infection with increased exclusivity of breastfeeding and durations of at least 3 months.* A couple papers demonstrated a "dose" effect relative to decreased occurrence of late onset sepsis in very low-birth-weight infants 73 and premature infants 245 associated with the infants receiving at least 50 mL/kg per day of mother' s milk compared with receiving other nutrition. Evidence shows that neutrophils found in human milk demonstrate signs of activation, including increased expression of CD11b (an adherence glycoprotein), decreased expression of L-selectin, spontaneous production of granulocyte-macrophage colony-stimulating factor (GM-CSF), and the ability to transform into CD1 + dendritic cells (DCs). cache = ./cache/cord-022544-7jn4ns6x.txt txt = ./txt/cord-022544-7jn4ns6x.txt === reduce.pl bib === === reduce.pl bib === === reduce.pl bib === === reduce.pl bib === === reduce.pl bib === === reduce.pl bib === === reduce.pl bib === === reduce.pl bib === id = cord-023942-vrs3je1x author = Powers, Karen S. title = Acute Pulmonary Infections date = 2011-12-16 pages = extension = .txt mime = text/plain words = 11273 sentences = 673 flesch = 42 summary = Acute lower respiratory infection is a common cause of morbidity in infants and children, and at times, requires intensive care and mechanical ventilation. Acute lower respiratory infection is a common cause of morbidity in infants and children, and at times, requires intensive care and mechanical ventilation. Viral bronchiolitis remains the leading cause for hospital admission in infancy and the most frequent cause of acute respiratory failure in children admitted to pediatric intensive care units in North America. In a study of hospitalized infants with congenital heart disease infected with RSV, 33% required intensive care, 19% received mechanical ventilation, and 3.4% died. In the 1990s, fi ve randomized trials involving 225 infants, evaluating the effect of nebulized adrenaline (epinephrine) on bronchiolitis showed clinical improvement, with reductions in oxygen requirement, respiratory rate, wheezing, and decrease in pulmonary vascular resistance. High incidence of pulmonary bacterial co-infection in children with severe respiratory syncytial virus (RSV) bronchiolitis cache = ./cache/cord-023942-vrs3je1x.txt txt = ./txt/cord-023942-vrs3je1x.txt === reduce.pl bib === === reduce.pl bib === === reduce.pl bib === === reduce.pl bib === === reduce.pl bib === === reduce.pl bib === === reduce.pl bib === === reduce.pl bib === id = cord-355292-n6sq2jz9 author = Chen, Yan title = Infants Born to Mothers With a New Coronavirus (COVID-19) date = 2020-03-16 pages = extension = .txt mime = text/plain words = 2625 sentences = 148 flesch = 56 summary = A novel viral respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is responsible for an epidemic of the coronavirus disease 2019 (COVID-19) in cases in China and worldwide. Four full-term, singleton infants were born to pregnant women who tested positive for COVID-19 in the city of Wuhan, the capital of Hubei province, China, where the disease was first identified. The other infant was born by vaginal delivery to a mother experiencing fever (highest temperature 38.3 • C), with a diagnostically confirmed infection. Recently, a finding from nine other cases suggested that there is no evidence for intrauterine infection caused by vertical transmission in women who develop COVID-19 pneumonia in late pregnancy (1) . This case report describes the clinical course of four live born infants born to pregnant women with the COVID-19 infection. This case report describes the clinical course of four live born infants born to pregnant women with the COVID-19 infection. cache = ./cache/cord-355292-n6sq2jz9.txt txt = ./txt/cord-355292-n6sq2jz9.txt === reduce.pl bib === === reduce.pl bib === id = cord-253520-phtmgy6g author = nan title = Vaccination schedule for infants and COVID-19 date = 2020-05-23 pages = extension = .txt mime = text/plain words = 265 sentences = 26 flesch = 64 summary = authors: nan title: Vaccination schedule for infants and COVID-19 Many parents have cancelled vaccination appointments for their infants as well as their older children. Fear of contagion in waiting rooms, doubts about the effects of vaccination on immunity in a pandemic period, and then containment, has led to a sharp decrease in vaccinations, mainly in infants. On April 1, 2020, the French Health Authority issued an opinion so that the vaccination schedule would not be delayed. The EPI-PHARE report on the use of city drugs during the Covid-19 period reveals that penta and hexavalent vaccines for infants have fallen by 23% and that deliveries of MMR and HPV vaccines have dropped by 50 to 70% during the last two weeks of March 2020 [1] . Infants must imperatively be vaccinated from the 2nd month, in order to acquire an effective protection as soon as possible against frequent and serious diseases at this age, particularly Usage des médicaments de ville en France durant l'épidémie de Covid-19 -point de situation à la fin mars 2020 cache = ./cache/cord-253520-phtmgy6g.txt txt = ./txt/cord-253520-phtmgy6g.txt === reduce.pl bib === === reduce.pl bib === id = cord-022592-g7rmzsv5 author = Wynn, James L. title = Pathophysiology of Neonatal Sepsis date = 2016-07-06 pages = extension = .txt mime = text/plain words = 22148 sentences = 1302 flesch = 39 summary = 14, 15, [27] [28] [29] [30] [31] [32] [33] Prematurity, low birth weight (especially infants weighing less than 1,000 g), male sex, a maternal vaginal culture positive for group B streptococcus (GBS), prolonged rupture of membranes, maternal intrapartum fever, and chorioamnionitis are strongly associated with an increased risk for early-onset sepsis. In addition to the initial inflammatory response including complement activation, molecular detection of PAMPs promotes IL-1β and IL-6 production, which in turn increases the production of multiple other innate proteins that possess valuable immune function and serve to reduce pathogen load. Very low birth weight preterm infants with early onset neonatal sepsis: the predominance of gram-negative infections continues in the National Institute of Child Health and Human Development Neonatal Research Network Very low birth weight preterm infants with early onset neonatal sepsis: the predominance of gram-negative infections continues in the National Institute of Child Health and Human Development Neonatal Research Network cache = ./cache/cord-022592-g7rmzsv5.txt txt = ./txt/cord-022592-g7rmzsv5.txt === reduce.pl bib === id = cord-022448-ungitgh9 author = Sergueef, Nicette title = Clinical Conditions date = 2009-05-15 pages = extension = .txt mime = text/plain words = 77343 sentences = 4418 flesch = 50 summary = Brachial plexus injury, fracture of the clavicle, pectus excavatum and carinatum, scoliosis, kyphosis and vertebral somatic dysfunctions are other commonly encountered conditions with structural and functional consequences that can be addressed with osteopathic manipulative treatment. Palpate the infant to identify membranous, myofascial and interosseous somatic dysfunction, particularly in the upper thoracic spine, pectoral girdle, cervico-occipital area and cranium (temporal bone, occiput, occipitomastoid suture and jugular foramen). Secondly, but concomitant with the above, the progressive fl exion of the cranial base, associated with the anteroposterior growth of the skull, contributes to positional changes of both the pterygoid processes, which become longer and more vertical, and the petrous portions of the temporal bones, which become externally rotated. Because of the relationships between the sympathetic nervous system and the upper thoracic spinal segments, the second and third cervical vertebrae, and between the parasympathetic nervous system and the sphenoid, maxilla or palatine bones, somatic dysfunction of any of these vertebral and cranial areas can result in dysfunction of the ANS with impact on nasal function. cache = ./cache/cord-022448-ungitgh9.txt txt = ./txt/cord-022448-ungitgh9.txt === reduce.pl bib === id = cord-305085-bv7udg9k author = Lawrence, Robert M. title = Chapter 13 Transmission of Infectious Diseases Through Breast Milk and Breastfeeding date = 2011-12-31 pages = extension = .txt mime = text/plain words = 45849 sentences = 2358 flesch = 45 summary = Postnatal exposure of susceptible infants to CMV, including premature infants without passively acquired maternal antibodies against CMV, infants born to CMV-seronegative mothers, and immunodeficient infants, can cause significant clinical illness (pneumonitis, hepatitis, thrombocytopenia).* In one study of premature infants followed up to 12 months, Vochem et al 430 found CMV transmission in 17 of 29 infants (59%) exposed to CMV virolactia and breastfed compared with no infants infected of 27 exposed to breast milk without CMV. 38, 104, 121 Laboratory reports demonstrate the presence of cell-free virus and cell-associated virus in breast milk as well as various immunologic factors that could block or limit infection.* A dose-response relationship has been observed, correlating the HIV viral load in human milk as well as a mother' s plasma viral load with an increased transmission risk for the breastfed infant. 76 No case of transmission of yellow fever virus from an infected mother to her infant via breastfeeding or breast milk has been reported. cache = ./cache/cord-305085-bv7udg9k.txt txt = ./txt/cord-305085-bv7udg9k.txt === reduce.pl bib === id = cord-332113-37g4regv author = Neu, Josef title = The Microbiome and Its Impact on Disease in the Preterm Patient date = 2013-10-01 pages = extension = .txt mime = text/plain words = 4238 sentences = 193 flesch = 36 summary = Although a commonly held belief is that the intestinal tract of the fetus is sterile, recent studies using a combination of culture and non-culture-based techniques suggest that many preterm infants are exposed to microbes found in the amniotic fluid, even without a history of rupture of membranes or culture-positive chorioamnionitis [10 • , 11] . Those infants born via C-section, fed formula milk and exposed to antibiotics have a decrease in diversity of intestinal microbiota and abnormal patterns of colonization with suppression of ''healthy'' bacteria such as Lactobacillus and Bifidobacteria. [31] Since many mothers delivered by C-section also receive antibiotics, whether they have a role in perturbing the newborn intestinal microecology remains unknown but is a confounding factor when one evaluates the epidemiology studies showing atopic disease, type 1 diabetes and food allergies in C-section versus vaginally delivered infants. Studies in animals and premature infants have shown that human milk decreases the incidence of necrotizing enterocolitis (NEC) [32, 33] . cache = ./cache/cord-332113-37g4regv.txt txt = ./txt/cord-332113-37g4regv.txt === reduce.pl bib === id = cord-346214-8ev9w4ko author = Unger, Sharon title = Gut microbiota of the very-low-birth-weight infant date = 2014-10-13 pages = extension = .txt mime = text/plain words = 5312 sentences = 223 flesch = 32 summary = Colonization of the GIT is perturbed by a number of factors prevalent among VLBW infants including: cesarean delivery, antibiotics (mother or infant), prolonged rupture of the membranes, parenteral feeding, delayed enteral feeding, slower GIT transit time, gestational age, birth weight, living in a populated neonatal intensive care unit with an enriched pathogen load, and lack of exposure to mother's skin and breast milk microbiome (1, (3) (4) (5) (6) 13, (17) (18) (19) (20) (21) (22) . There appear to be significant differences in the composition of the intestinal microbiota of preterm compared to term infants, with decreased bacterial diversity, increased pathogens potentially related to NEC, and a surprising increase in eukaryotic and viral diversity (3,6,23-30). The differences in colonization of human milk-fed compared with formula-fed infants are believed due, in part, to breast milk inoculating the GIT with its own rich microbiome and abundant source of oligosaccharides that selectively stimulate the growth and/or activity of beneficial bacteria (40, 41) . cache = ./cache/cord-346214-8ev9w4ko.txt txt = ./txt/cord-346214-8ev9w4ko.txt === reduce.pl bib === id = cord-005646-xhx9pzhj author = nan title = 2nd World Congress on Pediatric Intensive Care 1996 Rotterdam, The Netherlands, 23–26 June 1996 Abstracts of Oral Presentations, Posters and Nursing Programme date = 1996 pages = extension = .txt mime = text/plain words = 72031 sentences = 4734 flesch = 56 summary = Aims and methods The aim of both a prospective and retrospective survey conducted in German pediatric intensive care units in 1993 was to accumulate data on the epidemiology, risk factors, natural history and treatment strategies in a large group of pediatric ARDS patients who were treated in the tt~ee year period from 1991 to 1993.All patients had acute bilateral alveolar infiltration of noncardiogenic origin and a pO2~iO2 ratio < 150mmHg. The influence of sex, underlying disease and single organ failure was analyzed using the Fischer's exact test, the influence of additional organ failure on mortality was tested with the Cochran-Mantel-Haenszet statistics. cache = ./cache/cord-005646-xhx9pzhj.txt txt = ./txt/cord-005646-xhx9pzhj.txt === reduce.pl bib === id = cord-023767-rcv4pl0d author = O’Ryan, Miguel L. title = Microorganisms Responsible for Neonatal Diarrhea date = 2009-05-19 pages = extension = .txt mime = text/plain words = 45685 sentences = 2892 flesch = 44 summary = coli may disappear completely from stools of breast-fed children during the ensuing weeks, this disappearance is believed to be related to factors present in the human milk rather than the gastric secretions.5~302~303 The use of breast-feeding or expressed human milk has even been effective in terminating nursery epidemics caused by EPEC 0 11 1:B4, probably by reducing the incidence of crossinfections among infants.3033304 Although dose-effect studies have not been performed among newborns, severe diarrhea has occurred after ingestion of 10' EPEC organisms by very young The clinical syndrome is that of bloody, noninflammatory (sometimes voluminous) diarrhea that is distinct from febrile dysentery with fecal leukocytes seen in shigellosis or EIEC infection^.^^ Most cases of EHEC infections have been recognized in outbreaks of bloody diarrhea or HUS in daycare centers, schools, nursing homes, and c o m m~n i t i e s .~~~-~~~ Although EHEC infections often involve infants and young children, the frequency of this infection in neonates remains unclear; animal studies suggest that receptors for the Shiga toxin may be developmentally regulated and that susceptibility to disease may be age related. cache = ./cache/cord-023767-rcv4pl0d.txt txt = ./txt/cord-023767-rcv4pl0d.txt ===== Reducing email addresses cord-286479-p9d78t6v cord-337878-hiylqqie cord-330834-zqm4egei cord-005646-xhx9pzhj Creating transaction Updating adr table ===== Reducing keywords cord-007528-no92pmw0 cord-007036-gcdn13yc cord-010863-m36kxc4x cord-015172-hya08ch9 cord-000285-7p3b6tyf cord-018398-24pkhgn8 cord-014673-bb59z38j cord-279257-a7d9a2w1 cord-021571-7kbq0v9w cord-323354-igzs1rdm cord-023721-e0zp2gux cord-286479-p9d78t6v cord-258778-er0ug8w4 cord-005774-7z6uyn6p cord-010848-090yk40o cord-303322-d69o3z8d cord-018604-ua5h47jg cord-008165-qwyddp69 cord-337878-hiylqqie cord-004657-kmluql8h cord-010818-yz0gynn0 cord-022544-7jn4ns6x cord-011257-d12cj9v5 cord-269652-t7ghng17 cord-009144-3slh1nbk cord-016241-qom2rokn cord-265366-vmuqbpkk cord-338575-c04xxo8d cord-014951-2931ep31 cord-266373-8wuvk5cz cord-023942-vrs3je1x cord-296114-cyd9msls cord-022216-k4pi30sd cord-329022-0pymqxwq cord-032806-o6p861ms cord-011688-8g0p3vtm cord-314190-fvdock94 cord-355292-n6sq2jz9 cord-288113-ex4yi28u cord-253520-phtmgy6g cord-332113-37g4regv cord-022592-g7rmzsv5 cord-346214-8ev9w4ko cord-022448-ungitgh9 cord-023767-rcv4pl0d cord-005646-xhx9pzhj cord-330834-zqm4egei cord-305085-bv7udg9k Creating transaction Updating wrd table ===== Reducing urls cord-010848-090yk40o cord-337878-hiylqqie cord-011257-d12cj9v5 cord-269652-t7ghng17 cord-023942-vrs3je1x cord-011688-8g0p3vtm cord-288113-ex4yi28u cord-330834-zqm4egei Creating transaction Updating url table ===== Reducing named entities cord-007036-gcdn13yc cord-007528-no92pmw0 cord-010863-m36kxc4x cord-018398-24pkhgn8 cord-015172-hya08ch9 cord-000285-7p3b6tyf cord-279257-a7d9a2w1 cord-323354-igzs1rdm cord-014673-bb59z38j cord-021571-7kbq0v9w cord-023721-e0zp2gux cord-286479-p9d78t6v cord-258778-er0ug8w4 cord-005774-7z6uyn6p cord-010848-090yk40o cord-303322-d69o3z8d cord-018604-ua5h47jg cord-008165-qwyddp69 cord-337878-hiylqqie cord-004657-kmluql8h cord-010818-yz0gynn0 cord-011257-d12cj9v5 cord-016241-qom2rokn cord-009144-3slh1nbk cord-269652-t7ghng17 cord-022544-7jn4ns6x cord-265366-vmuqbpkk cord-338575-c04xxo8d cord-014951-2931ep31 cord-266373-8wuvk5cz cord-022216-k4pi30sd cord-296114-cyd9msls cord-314190-fvdock94 cord-023942-vrs3je1x cord-011688-8g0p3vtm cord-032806-o6p861ms cord-329022-0pymqxwq cord-355292-n6sq2jz9 cord-288113-ex4yi28u cord-253520-phtmgy6g cord-332113-37g4regv cord-346214-8ev9w4ko cord-330834-zqm4egei cord-022592-g7rmzsv5 cord-305085-bv7udg9k cord-022448-ungitgh9 cord-023767-rcv4pl0d cord-005646-xhx9pzhj Creating transaction Updating ent table ===== Reducing parts of speech cord-007036-gcdn13yc cord-007528-no92pmw0 cord-010863-m36kxc4x cord-000285-7p3b6tyf cord-279257-a7d9a2w1 cord-018398-24pkhgn8 cord-323354-igzs1rdm cord-023721-e0zp2gux cord-015172-hya08ch9 cord-005774-7z6uyn6p cord-010848-090yk40o cord-258778-er0ug8w4 cord-337878-hiylqqie cord-008165-qwyddp69 cord-303322-d69o3z8d cord-004657-kmluql8h cord-286479-p9d78t6v cord-018604-ua5h47jg cord-010818-yz0gynn0 cord-011257-d12cj9v5 cord-016241-qom2rokn cord-014673-bb59z38j cord-009144-3slh1nbk cord-269652-t7ghng17 cord-265366-vmuqbpkk cord-338575-c04xxo8d cord-014951-2931ep31 cord-266373-8wuvk5cz cord-296114-cyd9msls cord-011688-8g0p3vtm cord-032806-o6p861ms cord-355292-n6sq2jz9 cord-253520-phtmgy6g cord-288113-ex4yi28u cord-329022-0pymqxwq cord-022216-k4pi30sd cord-021571-7kbq0v9w cord-314190-fvdock94 cord-332113-37g4regv cord-023942-vrs3je1x cord-330834-zqm4egei cord-346214-8ev9w4ko cord-022544-7jn4ns6x cord-022592-g7rmzsv5 cord-023767-rcv4pl0d cord-305085-bv7udg9k cord-022448-ungitgh9 cord-005646-xhx9pzhj Creating transaction Updating pos table Building ./etc/reader.txt cord-023767-rcv4pl0d cord-305085-bv7udg9k cord-022592-g7rmzsv5 cord-305085-bv7udg9k cord-022544-7jn4ns6x cord-023767-rcv4pl0d number of items: 48 sum of words: 365,737 average size in words: 20,318 average readability score: 46 nouns: infants; infection; children; milk; infant; study; patients; age; risk; disease; breast; infections; birth; care; virus; treatment; sepsis; days; blood; transmission; neonates; months; cells; feeding; group; time; factors; weight; studies; cases; mother; term; child; use; results; development; breastfeeding; bronchiolitis; years; therapy; data; life; mothers; dysfunction; weeks; illness; hospital; diarrhea; levels; evidence verbs: associated; using; included; increased; occurring; done; showed; compare; following; developing; cause; found; reported; die; require; decrease; feeding; reduce; suggested; identified; demonstrates; receives; providing; treated; based; observed; result; considered; produce; related; described; born; performed; necrotizing; affect; improves; give; leads; see; remains; evaluated; prevent; determined; made; presented; measured; appear; assessed; involved; needed adjectives: respiratory; neonatal; human; clinical; severe; low; high; preterm; first; early; acute; lower; intestinal; viral; maternal; common; significant; important; different; bacterial; higher; immune; oral; positive; premature; intensive; specific; pulmonary; normal; present; newborn; pediatric; upper; possible; full; several; late; less; small; available; large; appropriate; mechanical; negative; many; similar; primary; congenital; young; non adverbs: also; however; well; often; significantly; usually; even; especially; particularly; therefore; frequently; less; respectively; previously; approximately; commonly; extremely; potentially; probably; still; generally; clinically; highly; typically; later; rarely; critically; early; furthermore; prior; recently; nt; rather; least; exclusively; relatively; now; normally; directly; almost; immediately; consequently; additionally; primarily; together; sometimes; rapidly; currently; mainly; forward pronouns: it; their; we; they; our; its; i; them; he; her; she; his; you; one; itself; us; themselves; your; me; iga1; s; oneself; himself; him; herself; thee; ours; my; mg; m; imperative?64; il12rb1; il-1ra; em; bear-2001; ar)d; -ten proper nouns: NEC; der; fl; NICU; RSV; S.; HIV; E.; mg; Salmonella; C.; kg; mit; Campylobacter; von; IgA; CMV; B; C; und; EPEC; fi; United; ICU; PCR; PH; ECMO; bei; States; II; SARS; jejuni; Hospital; Health; T; ARDS; A; Table; PICU; Escherichia; Fig; eine; zu; einer; GBS; RNA; refl; Shigella; IgG; Care keywords: infant; respiratory; infection; nec; child; nicu; neonatal; virus; preterm; patient; care; und; therapie; study; rsv; result; outbreak; mrsa; mit; milk; microbiota; intestinal; increase; human; group; feeding; factor; enterocolitis; ecmo; disease; die; der; day; covid-19; cell; case; bronchiolitis; breast; bei; year; west; werden; weight; von; vlbw; vitamin; ventilation; urti; upper; united one topic; one dimension: infants file(s): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7107579/ titles(s): Pneumocystis primary infection in infancy: Additional French data and review of the literature three topics; one dimension: infants; patients; der file(s): https://api.elsevier.com/content/article/pii/B9781437707885100136, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155703/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079845/ titles(s): Chapter 13 Transmission of Infectious Diseases Through Breast Milk and Breastfeeding | Clinical Conditions | Abstracts 2019 der GNPI und DGPI: 45. Jahrestagung der Gesellschaft für Neonatologie und Pädiatrische Intensivmedizin gemeinsam mit der 27. Jahrestagung der Deutschen Gesellschaft für Pädiatrische Infektiologie, 23.–25. Mai 2019, Leipzig five topics; three dimensions: infants infection milk; patients children respiratory; infants respiratory study; may dysfunction fi; der und die file(s): https://api.elsevier.com/content/article/pii/B9781437707885100136, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095092/, https://doi.org/10.1007/s12098-020-03376-y, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155703/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079845/ titles(s): Chapter 13 Transmission of Infectious Diseases Through Breast Milk and Breastfeeding | 2nd World Congress on Pediatric Intensive Care 1996 Rotterdam, The Netherlands, 23–26 June 1996 Abstracts of Oral Presentations, Posters and Nursing Programme | NeoCORE Conference Abstracts | Clinical Conditions | Abstracts 2019 der GNPI und DGPI: 45. Jahrestagung der Gesellschaft für Neonatologie und Pädiatrische Intensivmedizin gemeinsam mit der 27. Jahrestagung der Deutschen Gesellschaft für Pädiatrische Infektiologie, 23.–25. Mai 2019, Leipzig Type: cord title: keyword-infant-cord date: 2021-05-25 time: 15:17 username: emorgan patron: Eric Morgan email: emorgan@nd.edu input: keywords:infant ==== make-pages.sh htm files ==== make-pages.sh complex files ==== make-pages.sh named enities ==== making bibliographics id: cord-266373-8wuvk5cz author: Burns, Katherine H. title: Nurturing visual social development in the NICU date: 2020-09-05 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: nan url: https://www.ncbi.nlm.nih.gov/pubmed/32892211/ doi: 10.1038/s41372-020-00813-w id: cord-008165-qwyddp69 author: Candy, David C.A. title: Role of micro-organisms in necrotizing enterocolitis date: 2006-12-24 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: The frequency with which necrotizing enterocolitis occurs in outbreaks makes it likely that the illness can have an infective origin. Immunological and non-immunological defences of the gastrointestinal are impaired in early life. Consequently the gut of the preterm infant is predisposed to bacterial overgrowth. A wide range of pathogenic bacteria and viruses have been isolated from infants with necrotizing enterocolitis or detected histologically. The presence of bacterial metabolites in the breath, intestinal bullae (hydrogen) and urine (D-lactate) during the course of the illness is further confirmatory evidence. The presence of bacteria or bacterial products (such as exo- and endotoxin) in the circulation will lead to ischaemia of the intestine and other organs either directly or via mediators such as cytokines or platelet activating factor. Future studies in necrotizing enterocolitis should be directed to understanding and modulating inflammatory mediators in necrotizing enterocolitis and preventing the disease with breast milk and nutritional supplements (glutamine, short chain fatty acids), chemoprophylaxis, and antibodies. url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7129339/ doi: 10.1016/s1084-2756(97)80032-2 id: cord-303322-d69o3z8d author: Chang, Anne B title: Randomized placebo-controlled trial on azithromycin to reduce the morbidity of bronchiolitis in Indigenous Australian infants: rationale and protocol date: 2011-04-14 words: 5403.0 sentences: 287.0 pages: flesch: 37.0 cache: ./cache/cord-303322-d69o3z8d.txt txt: ./txt/cord-303322-d69o3z8d.txt summary: Our randomised, placebo-controlled trial of azithromycin in Indigenous infants hospitalised with bronchiolitis is designed to determine whether it can reduce short-term (and potentially long-term) morbidity from respiratory illness in Australian Indigenous infants who are at high risk of developing chronic respiratory illness. Indigenous infants (aged ≤ 24-months, expected number = 200) admitted to one of two regional hospitals (Darwin, Northern Territory and Townsville, Queensland) with a clinical diagnosis of bronchiolitis and fulfilling inclusion criteria are randomised (allocation concealed) to either azithromycin (30 mg/kg/dose) or placebo administered once weekly for three doses. Indigenous infants (aged ≤ 24-months, expected number = 200) admitted to one of two regional hospitals (Darwin, Northern Territory and Townsville, Queensland) with a clinical diagnosis of bronchiolitis and fulfilling inclusion criteria are randomised (allocation concealed) to either azithromycin (30 mg/kg/dose) or placebo administered once weekly for three doses. abstract: BACKGROUND: Acute lower respiratory infections are the commonest cause of morbidity and potentially preventable mortality in Indigenous infants. Infancy is also a critical time for post-natal lung growth and development. Severe or repeated lower airway injury in very young children likely increases the likelihood of chronic pulmonary disorders later in life. Globally, bronchiolitis is the most common form of acute lower respiratory infections during infancy. Compared with non-Indigenous Australian infants, Indigenous infants have greater bacterial density in their upper airways and more severe bronchiolitis episodes. Our study tests the hypothesis that the anti-microbial and anti-inflammatory properties of azithromycin, improve the clinical outcomes of Indigenous Australian infants hospitalised with bronchiolitis. METHODS: We are conducting a dual centre, randomised, double-blind, placebo-controlled, parallel group trial in northern Australia. Indigenous infants (aged ≤ 24-months, expected number = 200) admitted to one of two regional hospitals (Darwin, Northern Territory and Townsville, Queensland) with a clinical diagnosis of bronchiolitis and fulfilling inclusion criteria are randomised (allocation concealed) to either azithromycin (30 mg/kg/dose) or placebo administered once weekly for three doses. Clinical data are recorded twice daily and nasopharyngeal swab are collected at enrolment and at the time of discharge from hospital. Primary outcomes are 'length of oxygen requirement' and 'duration of stay,' the latter based upon being judged as 'ready for respiratory discharge'. The main secondary outcome is readmission for a respiratory illness within 6-months of leaving hospital. Descriptive virological and bacteriological (including development of antibiotic resistance) data from nasopharyngeal samples will also be reported. DISCUSSION: Two published studies, both involving different patient populations and settings, as well as different macrolide antibiotics and treatment duration, have produced conflicting results. Our randomised, placebo-controlled trial of azithromycin in Indigenous infants hospitalised with bronchiolitis is designed to determine whether it can reduce short-term (and potentially long-term) morbidity from respiratory illness in Australian Indigenous infants who are at high risk of developing chronic respiratory illness. If azithromycin is efficacious in reducing the morbidly of Indigenous infants hospitalised with bronchiolitis, the intervention would lead to improved short term (and possibly long term) health benefits. TRIAL REGISTRATION: Australia and New Zealand Clinical Trials Register (ANZCTR): ACTRN12610000326099 url: https://doi.org/10.1186/1745-6215-12-94 doi: 10.1186/1745-6215-12-94 id: cord-016241-qom2rokn author: Chen, Long title: Post-Newborn: A New Concept of Period in Early Life date: 2013-12-06 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: Post-newborn infants refer to infants from >28 days to <100 days after birth. During this period, infants are still completely dependent on breast milk or/and formula milk for feeding. Up to now, the concept of post-newborn has not been mentioned in classic textbooks. With the development of perinatal medicine, mortality rate of diseases in neonates such as premature infants, asphyxia, infectious diseases have decreased significantly, and consequently, issues of the quality of life for these survivors have aroused widespread concerns. The post-newborn infants have some important characteristics differing from both newborn infants and infants after the period: (1) different fatal diseases and mortality rate; (2) the diseases inherited from newborn period requiring early and prompt treatments; (3) some peculiar diseases during this period requiring much attention; (4) either similar or different immune function; (5) rapid growth and uneven development of organ systems. Establishment of the new concept of post-newborn will further reveal the nature of life, reduce the mortality rate of infants, and improve the quality of life. url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7120469/ doi: 10.1007/978-94-007-7618-0_143 id: cord-355292-n6sq2jz9 author: Chen, Yan title: Infants Born to Mothers With a New Coronavirus (COVID-19) date: 2020-03-16 words: 2625.0 sentences: 148.0 pages: flesch: 56.0 cache: ./cache/cord-355292-n6sq2jz9.txt txt: ./txt/cord-355292-n6sq2jz9.txt summary: A novel viral respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is responsible for an epidemic of the coronavirus disease 2019 (COVID-19) in cases in China and worldwide. Four full-term, singleton infants were born to pregnant women who tested positive for COVID-19 in the city of Wuhan, the capital of Hubei province, China, where the disease was first identified. The other infant was born by vaginal delivery to a mother experiencing fever (highest temperature 38.3 • C), with a diagnostically confirmed infection. Recently, a finding from nine other cases suggested that there is no evidence for intrauterine infection caused by vertical transmission in women who develop COVID-19 pneumonia in late pregnancy (1) . This case report describes the clinical course of four live born infants born to pregnant women with the COVID-19 infection. This case report describes the clinical course of four live born infants born to pregnant women with the COVID-19 infection. abstract: A novel viral respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is responsible for an epidemic of the coronavirus disease 2019 (COVID-19) in cases in China and worldwide. Four full-term, singleton infants were born to pregnant women who tested positive for COVID-19 in the city of Wuhan, the capital of Hubei province, China, where the disease was first identified. Of the three infants, for who consent to be diagnostically tested was provided, none tested positive for the virus. None of the infants developed serious clinical symptoms such as fever, cough, diarrhea, or abnormal radiologic or hematologic evidence, and all four infants were alive at the time of hospital discharge. Two infants had rashes of unknown etiology at birth, and one had facial ulcerations. One infant had tachypnea and was supported by non-invasive mechanical ventilation for 3 days. One had rashes at birth but was discharged without parental consent for a diagnostic test. This case report describes the clinical course of four live born infants, born to pregnant women with the COVID-19 infection. url: https://www.ncbi.nlm.nih.gov/pubmed/32266184/ doi: 10.3389/fped.2020.00104 id: cord-010863-m36kxc4x author: Croop, Sarah E. W. title: The Golden Hour: a quality improvement initiative for extremely premature infants in the neonatal intensive care unit date: 2019-11-11 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: BACKGROUND: Following delivery, extremely premature infants are vulnerable to rapid development of hypothermia and hypoglycemia. To reduce local rates of these morbidities, a multidisciplinary team developed a protocol standardizing evidence-based care practices during the first hour after birth. METHODS: Using quality improvement methodology, the Golden Hour protocol was implemented for all inborn infants <27 weeks’ gestation. Data were collected (2012–2017) over three phases; pre-protocol (n = 80), Phase I (n = 42), and Phase II (n = 92). RESULTS: There were no significant differences in infant characteristics. Improvements in hypothermia (59% vs 26% vs 38%; p = 0.001), hypoglycemia (18% vs 7% vs 4%; p = 0.012), and minutes to completion of stabilization [median (Q1,Q3) 110 (89,138) vs 111 (94,135) vs 92 (74,129); p = 0.0035] were observed. CONCLUSIONS: Implementation of an evidence-based, Golden Hour protocol is an effective intervention for reducing hypothermia and hypoglycemia in extremely premature infants. url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222905/ doi: 10.1038/s41372-019-0545-0 id: cord-018604-ua5h47jg author: Dersch-Mills, Deonne title: Assessment Considerations in Pediatric Patients date: 2018-12-28 words: 6368.0 sentences: 312.0 pages: flesch: 47.0 cache: ./cache/cord-018604-ua5h47jg.txt txt: ./txt/cord-018604-ua5h47jg.txt summary: Pharmacists need to be aware of this variability and use every patient encounter as an opportunity for assessment of many aspects of medication including dose, formulation, administration, and indication. Infants and children also have physiological differences that need to be considered especially when assessing efficacy, toxicity, and the patient''s overall response to medications through physical exam or use of laboratory values. Lastly, a lack of appropriate medication formulations for children creates a requirement for pharmacists to specifically assess the formulations, measurement, and administration of pediatric medications. Until children are mature enough to provide this information themselves (note that this age varies depending on the child), parents and other caregivers are relied upon to provide an accurate history of the patient''s illness(s) and medication(s). Because of the lack of appropriate information in the product labeling, alternative data sources need to be accessed to assess the use of the medication in an infant or child. abstract: Pharmacy assessment of pediatric patients is similar in many ways to that of adults; however there are many specific nuances that need to be considered in addition to the typical aspects included in an adult assessment. There is a lack of pediatric-specific medication research and a much higher rate of “off label” medication use, so children are at higher risk of medication errors and related harm. Pharmacokinetic differences and other age-related differences result in highly variable responses to medications throughout childhood. Pharmacists need to be aware of this variability and use every patient encounter as an opportunity for assessment of many aspects of medication including dose, formulation, administration, and indication. Infants and children also have physiological differences that need to be considered especially when assessing efficacy, toxicity, and the patient’s overall response to medications through physical exam or use of laboratory values. Lastly, a lack of appropriate medication formulations for children creates a requirement for pharmacists to specifically assess the formulations, measurement, and administration of pediatric medications. This chapter provides an approach to pediatric assessment, highlights common sources of error, and provides strategies for managing pediatric medications. url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7123523/ doi: 10.1007/978-3-030-11775-7_28 id: cord-323354-igzs1rdm author: Dornelles, Cristina T.L. title: Nutritional Status, Breastfeeding, and Evolution of Infants with Acute Viral Bronchiolitis date: 2007-09-17 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: Acute viral bronchiolitis is a common respiratory infectious disease of infancy. A prospective study was carried out with 175 infants aged up to six months to evaluate their nutritional and breastfeeding status as possible risk factors for unfavourable evolution of previously-healthy infants from a care hospital. Immunofluorescence test for virus and anthropometric assessment were performed. Outcomes were length of oxygen-use, length of hospital stay, and type of hospital unit needed. Seventy-three percent of the infants were well-nourished, 6% undernourished, 8.6% at a nutritional risk, 10.9% overweight, and 1.7% obese. Eighty-one percent of the undernourished and nutritionally at-risk infants and 72% of the well-nourished, overweight, and obese infants did not receive exclusive breastfeeding. The median length of hospital stay was four days and of oxygen-use was 60 hours. The nutritional status did not affect the clinical course of previously-healthy infants with acute viral brochiolitis. The duration of exclusive breastfeeding, but not type of breastfeeding, was inversely related to the length of oxygen-use and the length of hospital stay. Shorter exclusive breastfeeding was observed in infants who were assigned to a paediatric ward or to an intensive care unit. In conclusion, longer duration of breastfeeding was associated with better clinical outcomes. url: https://www.ncbi.nlm.nih.gov/pubmed/18330067/ doi: nan id: cord-330834-zqm4egei author: Drall, Kelsea M. title: Vitamin D supplementation in pregnancy and early infancy in relation to gut microbiota composition and C. difficile colonization: implications for viral respiratory infections date: 2020-08-11 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: In Canada and the US, the infant diet is supplemented with vitamin D via supplement drops or formula. Pregnant and nursing mothers often take vitamin D supplements. Since little is known about the impact of this supplementation on infant gut microbiota, we undertook a study to determine the association between maternal and infant vitamin D supplementation, infant gut microbiota composition and Clostridioides difficile colonization in 1,157 mother-infant pairs of the CHILD (Canadian Healthy Infant Longitudinal Development) Cohort Study over 2009–2012. Logistic and MaAsLin regression were employed to assess associations between vitamin D supplementation, and C. difficile colonization, or other gut microbiota, respectively. Sixty-five percent of infants received a vitamin D supplement. Among all infants, infant vitamin D supplementation was associated with a lower abundance of genus Megamonas (q = 0.01) in gut microbiota. Among those exclusively breastfed, maternal prenatal supplementation was associated with lower abundance of Bilophila (q = 0.01) and of Lachnospiraceae (q = 0.02) but higher abundance of Haemophilus (q = 0.02). There were no differences in microbiota composition with vitamin D supplementation among partially and not breastfed infants. Neither infant nor maternal vitamin D supplementation were associated with C. difficile colonization, after adjusting for breastfeeding status and other factors. However, maternal consumption of vitamin-D fortified milk reduced the likelihood of C. difficile colonization in infants (adjustedOR: 0.40, 95% CI: 0.19–0.82). The impact of this compositional difference on later childhood health, especially defense against viral respiratory infection, may go beyond the expected effects of vitamin D supplements and remains to be ascertained. url: https://doi.org/10.1080/19490976.2020.1799734 doi: 10.1080/19490976.2020.1799734 id: cord-004657-kmluql8h author: Eibl, Martha M. title: Prophylaxis of necrotizing enterocolitis by oral IgA-IgG: Review of a clinical study in low birth weight infants and discussion of the pathogenic role of infection date: 1990 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: Necrotizing enterocolitis, a severe gastrointestinal disease in the neonatal period, affects primarily premature infants. Perinatal complications that predispose the neonate to systemic hypoxia are frequent in infants with necrotizing enterocolitis. Ischemia of the intestinal mucosa may facilitate the invasion of enteric microorganisms in stressed low birth weight infants. Geographical and temporal clustering of outbreaks of the disease and the termination of epidemics by standard infection control underline the importance of infectious agents in the development of this disease. Several studies have established the immunoprotective effect of orally administered antibodies against infection of the gastrointestinal mucosa in children and adults. Anecdotal evidence suggested that feeding of human immune globulin might have a positive effect on the incidence of necrotizing enterocolitis in premature infants. This paper reviews a prospective, randomized, controlled trial of the efficacy of an oral immune globulin preparation (published in detail in theNew England Journal of Medicine, Vol. 319, pp. 1–7, 1988) and discusses the pathogenic role of infection in necrotizing enterocolitis. url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086514/ doi: 10.1007/bf00918694 id: cord-014951-2931ep31 author: El Basha, Noussa R. title: Prematurity, a significant predictor for worse outcome in viral bronchiolitis: a comparative study in infancy date: 2019-03-22 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: BACKGROUND: The rate of admissions to hospital with bronchiolitis has increased over the past years. The reasons for this are likely to be multifactorial including improved survival of preterm infants. AIM: To assess the severity of viral bronchiolitis in preterm compared to term infants admitted at a tertiary hospital in Cairo, Egypt, based on the outcome. PATIENTS AND METHODS: This prospective study was conducted throughout a 3-year period from September 2011 to October 2014. It included 153 infants, 74 healthy preterm, and 79 healthy term infants admitted with clinical diagnosis of bronchiolitis at a tertiary hospital in Cairo, Egypt. Bronchiolitis severity score (BSS) was recorded, and nasopharyngeal swabs were obtained from each patient at the time of presentation. Viruses were identified using reverse transcription polymerase chain reaction (RT-PCR). The clinical course and patient’s outcome were recorded. RESULTS: This study recorded a significantly more severe BSS for preterm compared to term infants. The preterm group had an increased mean length of hospital stay and oxygen therapy and was more likely to need intensive care unit admission and mechanical ventilation (MV) compared to the term group. The mean (± SD) BSS for infections with h-MPV, RSV, and para-influenza 3 was more significantly severe in preterm compared to term infants. Bacterial co-infection was significantly correlated with severity scoring in both groups. CONCLUSION: Prematurity significantly affects the severity of bronchiolitis, and this underscores the importance of early categorization as a high-risk group on their first visit. The physician should be aware that their illness runs a more severe course, even if they have no underlying disorders. url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7091660/ doi: 10.1186/s42506-019-0015-8 id: cord-288113-ex4yi28u author: Epalza, Cristina title: Role of Viral Molecular Panels in Diagnosing the Etiology of Fever in Infants Younger Than 3 Months date: 2019-11-09 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: As infants with proven viral infection present lower risk of bacterial infection, we evaluated how molecular methods detecting viruses on respiratory secretions could contribute to etiological diagnostic of these febrile episodes. From November 2010 to May 2011, we enrolled all febrile infants <90 days presenting to emergency room. Standard workup included viral rapid antigenic test and viral culture on nasopharyngeal aspirate. Samples negative by rapid testing were tested by molecular methods. From 208 febrile episodes (198 infants) with standard techniques, rate of documented microbiological etiology was 13% at emergency department, 47% during hospitalization, and 64% with viral cultures. Molecular methods increased microbiologically documented etiology rate by 12%, to 76%. Contribution of molecular methods was the highest in infants without clinical source of infection, increasing documentation by 18%, from 50% to 68%. Making viral molecular results rapidly available could help identifying a higher proportion of infants at low risk of serious bacterial infection. url: https://www.ncbi.nlm.nih.gov/pubmed/31709801/ doi: 10.1177/0009922819884582 id: cord-032806-o6p861ms author: Fenin, Audrey title: Very low birth weight infants receive full enteral nutrition within 2 postnatal weeks date: 2020-09-29 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: OBJECTIVE: Identify whether an enteral nutrition goal of reaching full feeds by 7 postnatal days for infants 1–1.5 kg and by 14 postnatal days for infants <1 kg was feasible and its associated outcomes. STUDY DESIGN: Very low birth weight infant cohort admitted in the first postnatal day and categorized as either Epoch 1 or Epoch 2, 12 months before and after implementation of a revised feeding protocol were compared. RESULT: In Epoch 2, 83% infants born 1–1.5 kg and 77% infants born <1 kg reached full feeds by 7 and 14 days compared to 26% and 25%, respectively in Epoch 1 (p < 0.0001). Central line and parental nutrition days were significantly lower in Epoch 2 compared to Epoch 1 with sustained and potentially improved infant growth. CONCLUSION: An evidence-based advancement feeding protocol was associated with achieving full feeds within the first 2 postnatal weeks for very low birth weight infants. url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522453/ doi: 10.1038/s41372-020-00819-4 id: cord-314190-fvdock94 author: Florin, Todd A title: Viral bronchiolitis date: 2017-01-01 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: Viral bronchiolitis is a common clinical syndrome affecting infants and young children. Concern about its associated morbidity and cost has led to a large body of research that has been summarised in systematic reviews and integrated into clinical practice guidelines in several countries. The evidence and guideline recommendations consistently support a clinical diagnosis with the limited role for diagnostic testing for children presenting with the typical clinical syndrome of viral upper respiratory infection progressing to the lower respiratory tract. Management is largely supportive, focusing on maintaining oxygenation and hydration of the patient. Evidence suggests no benefit from bronchodilator or corticosteroid use in infants with a first episode of bronchiolitis. Evidence for other treatments such as hypertonic saline is evolving but not clearly defined yet. For infants with severe disease, the insufficient available data suggest a role for high-flow nasal cannula and continuous positive airway pressure use in a monitored setting to prevent respiratory failure. url: https://doi.org/10.1016/s0140-6736(16)30951-5 doi: 10.1016/s0140-6736(16)30951-5 id: cord-000285-7p3b6tyf author: HARTERT, Tina V. title: The Tennessee Children's Respiratory Initiative: Objectives, design and recruitment results of a prospective cohort study investigating infant viral respiratory illness and the development of asthma and allergic diseases date: 2010-04-08 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: Background and objective: The ‘attack rate’ of asthma following viral lower respiratory tract infections (LRTI) is about 3–4 fold higher than that of the general population; however, the majority of children who develop viral LRTI during infancy do not develop asthma, and asthma incidence has been observed to continuously decrease with age. Thus, we do not understand how viral LRTI either predispose or serve as a marker of children to develop asthma. The Tennessee Children's Respiratory Initiative has been established as a longitudinal prospective investigation of infants and their biological mothers. The primary goals are to investigate both the acute and the long‐term health consequences of varying severity and aetiology of clinically significant viral respiratory tract infections on early childhood outcomes. Methods: Over four respiratory viral seasons, 2004–2008, term, non‐low birth weight previously healthy infants and their biological mothers were enrolled during an infant's acute viral respiratory illness. Longitudinal follow up to age 6 years is ongoing. Results: This report describes the study objectives, design and recruitment results of the over 650 families enrolled in this longitudinal investigation. The Tennessee Children's Respiratory Initiative is additionally unique because it is designed in parallel with a large retrospective birth cohort of over 95 000 mother–infant dyads with similar objectives to investigate the role of respiratory viral infection severity and aetiology in the development of asthma. Conclusions: Future reports from this cohort will help to clarify the complex relationship between infant respiratory viral infection severity, aetiology, atopic predisposition and the subsequent development of early childhood asthma and atopic diseases. url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992986/ doi: 10.1111/j.1440-1843.2010.01743.x id: cord-005774-7z6uyn6p author: Hammer, J. title: Infant lung function testing in the intensive care unit date: 1995 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: As a result of the previous shortage of tools to assess objectively the overall physiological status of the respiratory system in infants and young children, it has been difficult to measure the degree of physiological disorder or the response to therapy in respiratory diseases such as BPD, the pediatric version of ARDS, bronchiolitis, pneumonia, asthma and croup in this patient population. The newborn — four-year old child is particularly difficult to study because of their lack of cooperation and size. The recent progress in computer technology made pulmonary function testing available for this age range and opened up new possibilities for monitoring changes in disease processes affecting the respiratory system. This may improve medical management of infants and children with lung and heart diseases in particular. In 1989, Shannon [49] proposed in this Journal that the minimum physiological information needed for the intelligent use of mechanical ventilation (particularly if lower airway and/or pulmonary parenchymal disease was apparent) required the measurement of at least 4 variables: i) arterial partial pressure of carbon dioxide; ii) arterial oxygen saturation; iii) the mechanical time constant of the lung and iv) FRC. In many circumstances, arterial CO(2) is approximated by alveolar (end-tidal) CO(2) and the arterial oxygen saturation is obtained from pulse oximetry accurately if perfusion is adequate. The mechanical time constant and FRC are easily measured by the techniques described above and together provide important information concerning appropriate ventilator settings for a given disease. The described techniques bring new insights and awareness, but also new responsibilities in the management of infants and children with respiratory compromise. Not all of these techniques need to be applied to all infants in the ICU. Not all the assumptions upon which some of the techniques we have described are based will prove true. Any such methods which do not withstand solid scientific testing must be quickly discarded and replaced with better and (hopefully) easier methods. url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095417/ doi: 10.1007/bf01704742 id: cord-021571-7kbq0v9w author: Heath, Joan A. title: Infections Acquired in the Nursery: Epidemiology and Control date: 2009-05-19 words: 21244.0 sentences: 1014.0 pages: flesch: 41.0 cache: ./cache/cord-021571-7kbq0v9w.txt txt: ./txt/cord-021571-7kbq0v9w.txt summary: The fact that a hand hygiene campaign was associated with increased hand hygiene compliance and a lower rate of CONS-positive cultures supports this ~ontention.''~ Enterococcus has been shown to account for 10% of total nosocomial infections in neonates, 6% to 15% of bloodstream infections, 0% to 5% of cases of pneumonia, 17% of urinary tract infections, and 9% of surgical site Sepsis and meningitis are common manifestations of enterococcal infection during NICU outbreak^''^,^^; however, polymicrobial bacteremia and NEC frequently accompany enterococcal sepsis.77 Identified risk factors for enterococcal sepsis, after adjustment for birth weight, include use of a nonumbilical CVC, prolonged presence of a CVC, and bowel resection?'' Because Enterococcus colonizes the gastrointestinal tract and can survive for long periods of time on inanimate surfaces, the patient''s environment may become contaminated and, along with the infant, serve as a reservoir for ongoing spread of the organism. abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150280/ doi: 10.1016/b0-72-160537-0/50037-2 id: cord-329022-0pymqxwq author: Hughes, Michelle M title: Population-Based Pertussis Incidence and Risk Factors in Infants Less Than 6 Months in Nepal date: 2017-03-01 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: BACKGROUND: Pertussis is estimated to cause 2 percent of childhood deaths globally and is a growing public health problem in developed countries despite high vaccination coverage. Infants are at greatest risk of morbidity and mortality. Maternal vaccination during pregnancy may be effective to prevent pertussis in young infants, but population-based estimates of disease burden in infants are lacking, particularly in low-income countries. The objective of this study was to estimate the incidence of pertussis in infants less than 6 months of age in Sarlahi District, Nepal. METHODS: Nested within a population-based randomized controlled trial of influenza vaccination during pregnancy, infants were visited weekly from birth through 6 months to assess respiratory illness in the prior week. If any respiratory symptoms had occurred, a nasal swab was collected and tested with a multitarget pertussis polymerase chain reaction (PCR) assay. The prospective cohort study includes infants observed between May 2011 and August 2014. RESULTS: The incidence of PCR-confirmed Bordetella pertussis was 13.3 cases per 1000 infant-years (95% confidence interval, 7.7–21.3) in a cohort of 3483 infants with at least 1 day of follow-up. CONCLUSIONS: In a population-based active home surveillance for respiratory illness, a low risk for pertussis was estimated among infants in rural Nepal. Nepal’s immunization program, which includes a childhood whole cell pertussis vaccine, may be effective in controlling pertussis in infants. url: https://doi.org/10.1093/jpids/piw079 doi: 10.1093/jpids/piw079 id: cord-009144-3slh1nbk author: Jacobs, J.W. title: RESPIRATORY SYNCYTIAL AND OTHER VIRUSES ASSOCIATED WITH RESPIRATORY DISEASE IN INFANTS date: 1971-05-01 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: Diagnosis by virus isolation and serology was attempted in 377 cases of respiratory-tract infection in infants under one year of age admitted to hospital during two winters. A diagnosis of infection with respiratory syncytial (R.S.) virus was made in 40%, rhinovirus in 6·1%, adenovirus in 3·7%, parainfluenza in 2·1%, enterovirus in 1·9%, and influenza in 1·3%. R.S.-virus infections were more severe than others and occurred mostly in the first five months of life, with a peak at two months. Rhinovirus infections occurred at all ages, and often involved the lower respiratory tract. Of the 12 deaths, only 1 (due to R.S. virus) was not associated with a contributory cause. Maternal antibody to R.S. virus did not notably affect the incidence or severity of R.S.-virus infections. url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135715/ doi: 10.1016/s0140-6736(71)92440-8 id: cord-022216-k4pi30sd author: Kliegman, Robert M. title: Neonatal necrotizing enterocolitis date: 2009-05-15 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155452/ doi: 10.1016/b978-0-7216-3924-6.50047-0 id: cord-022544-7jn4ns6x author: Lawrence, Robert M. title: Host-Resistance Factors and Immunologic Significance of Human Milk date: 2010-12-27 words: 22268.0 sentences: 1177.0 pages: flesch: 45.0 cache: ./cache/cord-022544-7jn4ns6x.txt txt: ./txt/cord-022544-7jn4ns6x.txt summary: The immunologically active components of breast milk make up an important aspect of the host defenses of the mammary gland in the mother; at the same time, they complement, supplement, and stimulate the ongoing development of the infant'' s immune system. A number of other long-term studies demonstrated greater protection from infection with increased exclusivity of breastfeeding and durations of at least 3 months.* A couple papers demonstrated a "dose" effect relative to decreased occurrence of late onset sepsis in very low-birth-weight infants 73 and premature infants 245 associated with the infants receiving at least 50 mL/kg per day of mother'' s milk compared with receiving other nutrition. Evidence shows that neutrophils found in human milk demonstrate signs of activation, including increased expression of CD11b (an adherence glycoprotein), decreased expression of L-selectin, spontaneous production of granulocyte-macrophage colony-stimulating factor (GM-CSF), and the ability to transform into CD1 + dendritic cells (DCs). abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158292/ doi: 10.1016/b978-1-4377-0788-5.10005-7 id: cord-305085-bv7udg9k author: Lawrence, Robert M. title: Chapter 13 Transmission of Infectious Diseases Through Breast Milk and Breastfeeding date: 2011-12-31 words: 45849.0 sentences: 2358.0 pages: flesch: 45.0 cache: ./cache/cord-305085-bv7udg9k.txt txt: ./txt/cord-305085-bv7udg9k.txt summary: Postnatal exposure of susceptible infants to CMV, including premature infants without passively acquired maternal antibodies against CMV, infants born to CMV-seronegative mothers, and immunodeficient infants, can cause significant clinical illness (pneumonitis, hepatitis, thrombocytopenia).* In one study of premature infants followed up to 12 months, Vochem et al 430 found CMV transmission in 17 of 29 infants (59%) exposed to CMV virolactia and breastfed compared with no infants infected of 27 exposed to breast milk without CMV. 38, 104, 121 Laboratory reports demonstrate the presence of cell-free virus and cell-associated virus in breast milk as well as various immunologic factors that could block or limit infection.* A dose-response relationship has been observed, correlating the HIV viral load in human milk as well as a mother'' s plasma viral load with an increased transmission risk for the breastfed infant. 76 No case of transmission of yellow fever virus from an infected mother to her infant via breastfeeding or breast milk has been reported. abstract: nan url: https://api.elsevier.com/content/article/pii/B9781437707885100136 doi: 10.1016/b978-1-4377-0788-5.10013-6 id: cord-265366-vmuqbpkk author: Leibowitz, Jill title: Comparison of Clinical and Epidemiologic Characteristics of Young Febrile Infants with and without SARS-CoV-2 Infection date: 2020-10-09 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: OBJECTIVE: To determine features that distinguish febrile young infants with SARS-CoV-2 infection. STUDY DESIGN: Retrospective single-center study included febrile infants <57 days evaluated in the Emergency Department of Cohen Children’s Medical Center of Northwell Health, New Hyde Park, New York during March 1-April 30 of 2018, 2019, and 2020. Sociodemographic and clinical features were compared between those seen during the 2020 COVID-19 pandemic and previous years, as well as between SARS-CoV-2 infected infants and SARS-CoV-2 uninfected infants (SARS-CoV-2 negative or evaluated during 2018 and 2019). RESULTS: In all, 124 febrile infants <57 days of age were identified; 38 during the 2-month study period in 2018, 33 in 2019, and 53 in 2020. During 2020, fewer febrile infants had a serious bacterial infection (SBI) or a positive respiratory viral panel (RVP) than in prior years (6% versus 21%, P = .02; 15% versus 53%, p<.001, respectively). SARS-CoV-2 was the most frequent pathogen detected in 2020; of 30 infants tested, 20 tested positive. Infants with SARS-CoV-2 were more likely to identify as Hispanic (p=.004), have public insurance or were uninsured (p=.01), exhibited lethargy (p=.02), had feeding difficulties (p=.002), and had lower white blood cell (p=.001), neutrophil (p<.001), and lymphocyte counts (p=.005) than the 81 infants without SARS-CoV-2 infection. None of the infants with SARS-CoV-2 had concurrent SBI or detection of another virus. Overall, disease in infants with SARS-CoV-2 was mild. CONCLUSIONS: During the peak of the pandemic, SARS-CoV-2 was the predominant pathogen among febrile infants. Socioeconomic, historical, and laboratory features differed significantly between SARS-CoV-2 infected and uninfected infants. None of the 20 infants with SARS-CoV-2 infection had an identified co-viral or serious bacterial infection. url: https://www.sciencedirect.com/science/article/pii/S0022347620312646?v=s5 doi: 10.1016/j.jpeds.2020.10.002 id: cord-258778-er0ug8w4 author: Maayan-Metzger, Ayala title: Necrotizing Enterocolitis in Full-Term Infants: Case–Control Study and Review of the Literature date: 2004-07-01 words: 3267.0 sentences: 176.0 pages: flesch: 51.0 cache: ./cache/cord-258778-er0ug8w4.txt txt: ./txt/cord-258778-er0ug8w4.txt summary: OBJECTIVE: To examine the increasing number of full-term infants at our hospital exhibiting necrotizing enterocolitis (NEC) in order to characterize these cases and to discover common risk factors. METHODS: Medical charts were reviewed for all full-term infants (gestational age > 36 weeks) that were born in our institution during a 5-year period (from January 1, 1998 to December 31, 2002) and that developed definite NEC. NEC in full-term infants is well documented, accounting for about 10% of babies with NEC; it usually involves babies with known risk factors, such as intrauterine growth retardation (IUGR), birth asphyxia, congenital heart disease, gastroschisis, polycythemia, hypoglycemia, sepsis, exchange transfusion, umbilical lines, milk allergy, premature rupture of membranes with and without chorioamnionitis and gestational diabetes. The findings of the current study show that only half of these full-term infants with NEC exhibited known predisposing risk factors, including congenital heart disease, undiagnosed syndrome, birth asphyxia, intrauterine growth retardation and congenital hypothyroidism. abstract: OBJECTIVE: To examine the increasing number of full-term infants at our hospital exhibiting necrotizing enterocolitis (NEC) in order to characterize these cases and to discover common risk factors. METHODS: Medical charts were reviewed for all full-term infants (gestational age > 36 weeks) that were born in our institution during a 5-year period (from January 1, 1998 to December 31, 2002) and that developed definite NEC. Data regarding the rate of Cesarean section (CS) in our institution over the study period and five years prior to the study was also recorded. RESULTS: During the 5 years of the study, 14 full-term infants were found to have NEC. The incidence of NEC in full-term infants increased from 0.16 to 0.71 per 1000 live births in the 5-year period. Mean birth weight was 2829 g. All the NEC infants except one were delivered by CS, and all of them were fed either with a mixture of breast milk and formula or entirely by formula. Seven of the infants (50%) had no major known risk factors predisposing them for NEC. Mean age of disease onset was very early (4.1 days) in most of the infants (12 infants), and the colon was the main NEC site. The short-term outcome was favorable in all but one case, which required explorative laparotomy for intestinal perforation. The number of infants born by CS has been steadily increasing, and was almost three times greater during the study period in comparison to the preceding years. CONCLUSIONS: The etiology of NEC in the full-term population seems to differ from the etiology for the preterm group in its intestinal location and in the timing of its onset. The increase in the rate of CS over the years might be related to the concurrent increase in NEC, and this relationship should be further investigated. url: https://www.ncbi.nlm.nih.gov/pubmed/15229620/ doi: 10.1038/sj.jp.7211135 id: cord-296114-cyd9msls author: Mallol, J. title: Common cold decreases lung function in infants with recurrent wheezing date: 2009-11-27 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: BACKGROUND: Common acute viral respiratory infections (colds) are the most frequent cause of exacerbations in infants with recurrent wheezing (RW). However, there is no quantitative information about the effect of colds on the lung function of infants with RW. This study was undertaken to determine the effect of common cold on forced expiratory parameters measured from raised lung volume in infants with RW. METHODS: Spirometric lung function (expiratory flows from raised lung volume) was randomly assessed in 28 infants with RW while they had a common cold and when asymptomatic. RESULTS: It was found that during colds there was a significant decrease in all forced expiratory parameters and this was much more evident for flows (FEF(50%), FEF(75%) and FEF(25–75%)) which were definitively abnormal (less than −1.65 z-score) in the majority of infants. There was not association between family asthma, tobacco exposure, and other factors, with the extent of lung function decrease during colds. Tobacco during pregnancy but not a history of family asthma was significantly associated to lower expiratory flows; however, the association was significant only when infants were asymptomatic. CONCLUSION: This study shows that common colds cause a marked reduction of lung function in infants with RW. url: https://www.sciencedirect.com/science/article/pii/S0301054609001098 doi: 10.1016/j.aller.2009.10.001 id: cord-011257-d12cj9v5 author: McEvoy, Cindy T. title: Dose-escalation trial of budesonide in surfactant for prevention of bronchopulmonary dysplasia in extremely low gestational age high-risk newborns (SASSIE) date: 2020-02-01 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: BACKGROUND: Initial trials of lung-targeted budesonide (0.25 mg/kg) in surfactant to prevent bronchopulmonary dysplasia (BPD) in premature infants have shown benefit; however, the optimal safe dose is unknown. METHODS: Dose-escalation study of budesonide (0.025, 0.05, 0.10 mg/kg) in calfactatant in extremely low gestational age neonates (ELGANs) requiring intubation at 3−14 days. Tracheal aspirate (TA) cytokines, blood budesonide concentrations, and untargeted blood metabolomics were measured. Outcomes were compared with matched infants receiving surfactant in the Trial Of Late SURFactant (TOLSURF). RESULTS: Twenty-four infants with mean gestational age 25.0 weeks and 743 g birth weight requiring mechanical ventilation were enrolled at mean age 6 days. Budesonide was detected in the blood of all infants with a half-life of 3.4 h. Of 11 infants with elevated TA cytokine levels at baseline, treatment was associated with sustained decrease (mean 65%) at all three dosing levels. There were time- and dose-dependent decreases in blood cortisol concentrations and changes in total blood metabolites. Respiratory outcomes did not differ from the historic controls. CONCLUSIONS: Budesonide/surfactant had no clinical respiratory benefit at any dosing levels for intubated ELGANs. One-tenth the dose used in previous trials had minimal systemic metabolic effects and appeared effective for lung-targeted anti-inflammatory action. url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7223897/ doi: 10.1038/s41390-020-0792-y id: cord-023721-e0zp2gux author: Meissner, H. Cody title: Bronchiolitis date: 2013-02-10 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173523/ doi: 10.1016/b978-1-4377-2702-9.00033-7 id: cord-337878-hiylqqie author: Namasivayam, Abirami title: Atypical case of COVID-19 in a critically unwell 5-week old infant date: 2020-09-14 words: 2519.0 sentences: 153.0 pages: flesch: 49.0 cache: ./cache/cord-337878-hiylqqie.txt txt: ./txt/cord-337878-hiylqqie.txt summary: To our knowledge, he is the youngest reported case in the UK to require mechanical ventilation and intensive care treatment as a direct result of COVID-19 following horizontal transmission. 4 A larger nationwide study investigating 134 paediatric cases across China reported that 76% cases had fever, 64.9% cases presented as acute upper respiratory tract infection, 26.9% as mild pneumonia and 1.5% cases were critical; unfortunately, the specific age groups and comorbidities were not reported. At present there are few reports of paediatric patients requiring intensive care support with confirmed COVID-19. This case demonstrates the need for vigilance in considering COVID-19 infection in infants presenting with less discriminatory symptoms such as lethargy or reduced feeding. Dong et al report a case series of 2135 paediatric patients with confirmed and suspected coronavirus; infants (<1 year) were noted to be particularly vulnerable. abstract: The effect of COVID-19 by SARS-CoV-2 on the paediatric population remains an evolving mystery. Early reports from China stated that children seem to be unharmed by its dangerous effects, yet more recently there has been evidence of a systemic inflammatory response in a small number of children who are affected. We discuss a 5-week-old male infant who presented atypically with severe COVID-19 infection. To our knowledge, he is the youngest reported case in the UK to require mechanical ventilation and intensive care treatment as a direct result of COVID-19 following horizontal transmission. This case has generated several learning points with regard to atypical presentations of COVID-19 and identifying a potential cohort of ‘at risk’ infants. We also highlight a number of new challenges that have arisen for paediatricians and anaesthetists providing airway management for infants with SARS-CoV-2. url: https://www.ncbi.nlm.nih.gov/pubmed/32928837/ doi: 10.1136/bcr-2020-237142 id: cord-332113-37g4regv author: Neu, Josef title: The Microbiome and Its Impact on Disease in the Preterm Patient date: 2013-10-01 words: 4238.0 sentences: 193.0 pages: flesch: 36.0 cache: ./cache/cord-332113-37g4regv.txt txt: ./txt/cord-332113-37g4regv.txt summary: Although a commonly held belief is that the intestinal tract of the fetus is sterile, recent studies using a combination of culture and non-culture-based techniques suggest that many preterm infants are exposed to microbes found in the amniotic fluid, even without a history of rupture of membranes or culture-positive chorioamnionitis [10 • , 11] . Those infants born via C-section, fed formula milk and exposed to antibiotics have a decrease in diversity of intestinal microbiota and abnormal patterns of colonization with suppression of ''''healthy'''' bacteria such as Lactobacillus and Bifidobacteria. [31] Since many mothers delivered by C-section also receive antibiotics, whether they have a role in perturbing the newborn intestinal microecology remains unknown but is a confounding factor when one evaluates the epidemiology studies showing atopic disease, type 1 diabetes and food allergies in C-section versus vaginally delivered infants. Studies in animals and premature infants have shown that human milk decreases the incidence of necrotizing enterocolitis (NEC) [32, 33] . abstract: Emerging technologies derived largely from the Human Genome Project are being applied to evaluating the intestinal microbiota in preterm infants. The microbial ecology of the developing intestine is highly related to health and disease and new discoveries are emerging that will help us understand disorders in the development of the intestinal microbial ecosystem and how to eventually manipulate them to prevent diseases such as necrotizing enterocolitis and late onset sepsis. Here, a brief overview of the developing microbiome as it pertains to several aspects of health and disease in the preterm infant is presented. url: https://www.ncbi.nlm.nih.gov/pubmed/25422793/ doi: 10.1007/s40124-013-0031-7 id: cord-007036-gcdn13yc author: Nevez, Gilles title: Pneumocystis primary infection in infancy: Additional French data and review of the literature date: 2019-05-25 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: Data on features of Pneumocystis primary infection in infancy are still fragmented. To study Pneumocystis primary infection, 192 infants who were monitored for acute pulmonary disease or fever over a 40-month period were retrospectively investigated. P. jirovecii detection on archival nasopharyngeal aspirates was performed using a qPCR assay. Factors associated with P. jirovecii were assessed using univariate and multivariate analyses. P. jirovecii genotypes in infants and a control group of adults contemporaneously diagnosed with Pneumocystis pneumonia were identified using unilocus, bilocus, and multilocus sequence typing (MLST). P. jirovecii was detected in 35 infants (18.2%). The univariate analysis pointed out four factors: viral infection (P = .035, OR [IC 95], 2.2 [1.1–4.7]), lower respiratory tract infection (P = .032, OR [IC 95], 2.5 [1.1–5.9]), absence of hospital discharge after birth (P = .003, OR (IC 95), 0.1 (0.02–0.5]), and the 63–189-day group (P < .001, OR [IC 95], 42.2 [5.4–332]). The multivariate analysis confirmed these two latter factors (P = .02, OR [IC 95], 0.1 [0.02–0.72]; P = .005, OR [IC 95], 11.5 [2.1–63.5]). Thus, P. jirovecii acquisition mostly takes place in the community. A comparison of these data with those of previously published studies showed that median and interquartile range of positive-infant ages were close to those observed in Chile, Denmark, and Peru, highlighting similar characteristics. Common unilocus or bilocus genotypes were identified in infants and adults, whereas no MLST genotypes were shared. Therefore, a common reservoir made up of infected infants and adults is still hypothetical. Finally, primary infection is a worldwide phenomenon occurring at the same time in childhood regardless of geographical location, rather than an incidental event. url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7107579/ doi: 10.1093/mmy/myz040 id: cord-018398-24pkhgn8 author: O'Riordan, Declan title: Neonatal Care and Data date: 2009 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: Neonatology encompasses the care of all infants: from term newborns to extremely premature infants, from healthy infants to those suffering from severe infections or genetic disorders. While the management of infants can vary greatly, there are essential core data and knowledge that is needed to care for them. url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7123259/ doi: 10.1007/978-0-387-76446-7_4 id: cord-023767-rcv4pl0d author: O’Ryan, Miguel L. title: Microorganisms Responsible for Neonatal Diarrhea date: 2009-05-19 words: 45685.0 sentences: 2892.0 pages: flesch: 44.0 cache: ./cache/cord-023767-rcv4pl0d.txt txt: ./txt/cord-023767-rcv4pl0d.txt summary: coli may disappear completely from stools of breast-fed children during the ensuing weeks, this disappearance is believed to be related to factors present in the human milk rather than the gastric secretions.5~302~303 The use of breast-feeding or expressed human milk has even been effective in terminating nursery epidemics caused by EPEC 0 11 1:B4, probably by reducing the incidence of crossinfections among infants.3033304 Although dose-effect studies have not been performed among newborns, severe diarrhea has occurred after ingestion of 10'' EPEC organisms by very young The clinical syndrome is that of bloody, noninflammatory (sometimes voluminous) diarrhea that is distinct from febrile dysentery with fecal leukocytes seen in shigellosis or EIEC infection^.^^ Most cases of EHEC infections have been recognized in outbreaks of bloody diarrhea or HUS in daycare centers, schools, nursing homes, and c o m m~n i t i e s .~~~-~~~ Although EHEC infections often involve infants and young children, the frequency of this infection in neonates remains unclear; animal studies suggest that receptors for the Shiga toxin may be developmentally regulated and that susceptibility to disease may be age related. abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173613/ doi: 10.1016/b0-72-160537-0/50022-0 id: cord-007528-no92pmw0 author: Pineda, Roberta title: Preterm infant feeding performance at term equivalent age differs from that of full-term infants date: 2020-02-17 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: OBJECTIVE: To identify differences in feeding skill performance among preterm infants at term equivalent age compared with full-term infants. STUDY DESIGN: Ninety-two infants (44 preterm infants born ≤32 weeks gestation at term equivalent age and 48 full-term infants within 4 days of birth) had a standardized oral feeding assessment. RESULT: Preterm infants at term equivalent age had lower Neonatal Eating Outcome Assessment scores (67.8 ± 13.6 compared with 82.2 ± 8.1; p < 0.001) and were more likely to have poor arousal (p = 0.04), poor tongue positioning (p = 0.04), suck–swallow–breathe discoordination (p < 0.001), inadequate sucking bursts (p = 0.01), tonal abnormalities (p < 0.001), discoordination of the jaw and tongue during sucking (p < 0.001), lack of positive engagement with the feeder and/or discomfort (p < 0.001), signs of aspiration (p < 0.001), difficulty regulating breathing (p < 0.001), and have an inability to maintain an appropriate state (p < 0.001), and complete the feeding (<0.001). CONCLUSION: A broad range of feeding-related difficulties appear to remain evident in preterm infants at term equivalent age. url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117861/ doi: 10.1038/s41372-020-0616-2 id: cord-023942-vrs3je1x author: Powers, Karen S. title: Acute Pulmonary Infections date: 2011-12-16 words: 11273.0 sentences: 673.0 pages: flesch: 42.0 cache: ./cache/cord-023942-vrs3je1x.txt txt: ./txt/cord-023942-vrs3je1x.txt summary: Acute lower respiratory infection is a common cause of morbidity in infants and children, and at times, requires intensive care and mechanical ventilation. Acute lower respiratory infection is a common cause of morbidity in infants and children, and at times, requires intensive care and mechanical ventilation. Viral bronchiolitis remains the leading cause for hospital admission in infancy and the most frequent cause of acute respiratory failure in children admitted to pediatric intensive care units in North America. In a study of hospitalized infants with congenital heart disease infected with RSV, 33% required intensive care, 19% received mechanical ventilation, and 3.4% died. In the 1990s, fi ve randomized trials involving 225 infants, evaluating the effect of nebulized adrenaline (epinephrine) on bronchiolitis showed clinical improvement, with reductions in oxygen requirement, respiratory rate, wheezing, and decrease in pulmonary vascular resistance. High incidence of pulmonary bacterial co-infection in children with severe respiratory syncytial virus (RSV) bronchiolitis abstract: Acute lower respiratory infection is a common cause of morbidity in infants and children, and at times, requires intensive care and mechanical ventilation. Viral bronchiolitis and bacterial pneumonia account for the majority of lower respiratory tract infections that lead to respiratory insufficiency and pediatric intensive care admission. Twenty-seven percent of children who require mechanical ventilation for at least 24 h in pediatric intensive care units are diagnosed with bronchiolitis and 16% have the diagnosis of pneumonia. The median length of time intubated for an acute pulmonary infection leading to respiratory failure is approximately 7 days. url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178869/ doi: 10.1007/978-0-85729-923-9_25 id: cord-279257-a7d9a2w1 author: Puig, Carme title: Incidence and risk factors of lower respiratory tract illnesses during infancy in a Mediterranean birth cohort date: 2008-07-09 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: Aim: To investigate the incidence rate, viral respiratory agents and determinants of lower respiratory tract illnesses (LRTIs) in infants younger than 1 year. Methods: A total of 487 infants were recruited at birth for the Asthma Multicenter Infant Cohort Study in Barcelona (Spain). Cases of LRTIs were ascertained through an active register including a home visit and viral test in nasal lavage specimens during the first year of life. Cotinine in cord blood, household aeroallergens, indoor NO(2) and maternal and neonatal IgE were measured. Other maternal and infants' characteristics were obtained from structured questionnaires. Results: The incidence rate of at least one LRTI was 38.7 infants per 100 persons‐years. The most frequently isolated viral agent was respiratory syncytial virus (44.7%). The risk of LRTIs was higher in infants with a maternal history of asthma and in those with siblings (OR = 2.4; 95% CI: 0.98–6.08 and OR = 1.8; 95% CI: 1.04–3.21, respectively). The risk of LRTIs was lower in infants who were breast fed for more than 12 weeks (OR = 0.26; 95% CI: 0.26–0.86) and in those from a low socioeconomic class (OR = 0.16; 95% CI: 0.06–0.42). Conclusion: Viral LRTIs are frequent in infants younger than 1 year of age and there is an inter‐relationship between maternal asthma, siblings, breast feeding and socioeconomic status. url: https://www.ncbi.nlm.nih.gov/pubmed/18631341/ doi: 10.1111/j.1651-2227.2008.00939.x id: cord-269652-t7ghng17 author: Santos, Roberto Parulan title: A Practical Guide to the Diagnosis, Treatment, and Prevention of Neonatal Infections date: 2015-04-30 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: Neonatal infections continue to cause morbidity and mortality in infants. Among approximately 400,000 infants followed nationally, the incidence rates of early-onset sepsis infection within 3 days of life are 0.98 cases per 1000 live births. Newborn infants are at increased risk for infections because they have relative immunodeficiency. This article provides evidence-based practical approaches to the diagnosis, management, and prevention of neonatal infections. url: https://api.elsevier.com/content/article/pii/S0031395514002557 doi: 10.1016/j.pcl.2014.11.010 id: cord-022448-ungitgh9 author: Sergueef, Nicette title: Clinical Conditions date: 2009-05-15 words: 77343.0 sentences: 4418.0 pages: flesch: 50.0 cache: ./cache/cord-022448-ungitgh9.txt txt: ./txt/cord-022448-ungitgh9.txt summary: Brachial plexus injury, fracture of the clavicle, pectus excavatum and carinatum, scoliosis, kyphosis and vertebral somatic dysfunctions are other commonly encountered conditions with structural and functional consequences that can be addressed with osteopathic manipulative treatment. Palpate the infant to identify membranous, myofascial and interosseous somatic dysfunction, particularly in the upper thoracic spine, pectoral girdle, cervico-occipital area and cranium (temporal bone, occiput, occipitomastoid suture and jugular foramen). Secondly, but concomitant with the above, the progressive fl exion of the cranial base, associated with the anteroposterior growth of the skull, contributes to positional changes of both the pterygoid processes, which become longer and more vertical, and the petrous portions of the temporal bones, which become externally rotated. Because of the relationships between the sympathetic nervous system and the upper thoracic spinal segments, the second and third cervical vertebrae, and between the parasympathetic nervous system and the sphenoid, maxilla or palatine bones, somatic dysfunction of any of these vertebral and cranial areas can result in dysfunction of the ANS with impact on nasal function. abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155703/ doi: 10.1016/b978-0-443-10352-0.50013-4 id: cord-010818-yz0gynn0 author: Soliman, Yasser title: Respiratory outcomes of late preterm infants of mothers with early and late onset preeclampsia date: 2019-09-24 words: 3709.0 sentences: 207.0 pages: flesch: 49.0 cache: ./cache/cord-010818-yz0gynn0.txt txt: ./txt/cord-010818-yz0gynn0.txt summary: OBJECTIVE: To study the effect of early and late onset preeclampsia (EOPE, LOPE, respectively) on outcomes of late preterm infants. The objective of our study was to investigate the effects of early and late onset preeclampsia on the outcomes of late preterm infants, with the primary objective being respiratory outcomes. Late preterm infants born between 34 +0 and 36 +6 gestation to a mother with early onset preeclampsia between January 2014 and July 2015 were included in the study. Gouyon et al., using a large cohort from France, reported higher risk of severe respiratory morbidity, in late preterm infants of mothers with hypertensive disorder of pregnancy [9] . Respiratory morbidity, defined by the need for oxygen, CPAP or mechanical ventilation was higher at each gestational age in infants of hypertensive mothers but reached statistical significance only at 37 weeks. compared outcomes of late preterm infants of mothers with preeclampsia, gestational hypertension and normotensive pregnancies in a large cohort from the Netherlands [25] . abstract: OBJECTIVE: To study the effect of early and late onset preeclampsia (EOPE, LOPE, respectively) on outcomes of late preterm infants. STUDY DESIGN: Cohort study of late preterm infants admitted to a tertiary care NICU from January 2014–July 2015. Outcomes of late preterm infants of EOPE mothers were compared with the next late preterm infant of a LOPE mother and the next two late preterm infants of normotensive non-PE mothers. Primary outcome comprised use of continuous positive airway pressure, mechanical ventilation and/or surfactant in the 24 h after birth. RESULTS: Compared to normotensives (n = 131), adjusted odds ratio (AORs) of the primary outcome was higher in the EOPE (n = 64) and LOPE (n = 65) groups but reached statistical significance only in the EOPE group, AORs 12.9, 95% CI 3.5–37 and 2.7, 95% CI 0.95–8.1, respectively. CONCLUSIONS: Compared to late preterm infants of normotensive and LOPE mothers, infants of mothers with EOPE have significantly higher respiratory morbidity. url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222144/ doi: 10.1038/s41372-019-0497-4 id: cord-338575-c04xxo8d author: Stuebe, Alison title: Should Infants Be Separated from Mothers with COVID-19? First, Do No Harm date: 2020-05-01 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: nan url: https://doi.org/10.1089/bfm.2020.29153.ams doi: 10.1089/bfm.2020.29153.ams id: cord-346214-8ev9w4ko author: Unger, Sharon title: Gut microbiota of the very-low-birth-weight infant date: 2014-10-13 words: 5312.0 sentences: 223.0 pages: flesch: 32.0 cache: ./cache/cord-346214-8ev9w4ko.txt txt: ./txt/cord-346214-8ev9w4ko.txt summary: Colonization of the GIT is perturbed by a number of factors prevalent among VLBW infants including: cesarean delivery, antibiotics (mother or infant), prolonged rupture of the membranes, parenteral feeding, delayed enteral feeding, slower GIT transit time, gestational age, birth weight, living in a populated neonatal intensive care unit with an enriched pathogen load, and lack of exposure to mother''s skin and breast milk microbiome (1, (3) (4) (5) (6) 13, (17) (18) (19) (20) (21) (22) . There appear to be significant differences in the composition of the intestinal microbiota of preterm compared to term infants, with decreased bacterial diversity, increased pathogens potentially related to NEC, and a surprising increase in eukaryotic and viral diversity (3,6,23-30). The differences in colonization of human milk-fed compared with formula-fed infants are believed due, in part, to breast milk inoculating the GIT with its own rich microbiome and abundant source of oligosaccharides that selectively stimulate the growth and/or activity of beneficial bacteria (40, 41) . abstract: The microbiome, of which the bacterial component alone (microbiota), is estimated to include 10 times more cells than human cells of the body, blooms immediately after birth and evolves in composition and complexity throughout childhood. The gut microbiome has a profound impact on gastrointestinal tract development, maintenance of mucosal surface integrity, and contributes to the nutritional status of the host and thus plays a pivotal role in health and disease. New technologies have enabled the detailed characterization of normal microbial symbionts and dysbiosis–disease associations. This review summarizes the stepwise establishment of the intestinal microbiota, influential environmental factors, and how this may be perturbed in preterm very-low-birth-weight infants. The contribution of the microbiota to provision of energy and nutrients for intestinal development and the nutritional status of the host are reviewed. In addition, the crucial role of the gut microbiota in maintaining mucosal integrity is explored along with how its breakdown can lead to sepsis, necrotizing enterocolitis, and systemic inflammatory response syndrome. Finally, the role of enteral feeding type (human milk, formula, and nutrient fortification) in mediating these processes is discussed, and guidance is provided for nutritional strategies to promote health in these fragile infants. SUPPLEMENTARY INFORMATION: The online version of this article (doi:10.1038/pr.2014.162) contains supplementary material, which is available to authorized users. url: https://doi.org/10.1038/pr.2014.162 doi: 10.1038/pr.2014.162 id: cord-011688-8g0p3vtm author: Wang, Ting-Ting title: Perinatal risk factors for pulmonary hemorrhage in extremely low-birth-weight infants date: 2019-11-04 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: BACKGROUND: Pulmonary hemorrhage (PH) is a life-threatening respiratory complication of extremely low-birth-weight infants (ELBWIs). However, the risk factors for PH are controversial. Therefore, the purpose of this study was to analyze the perinatal risk factors and short-term outcomes of PH in ELBWIs. METHODS: This was a retrospective cohort study of live born infants who had birth weights that were less than 1000 g, lived for at least 12 hours, and did not have major congenital anomalies. A logistic regression model was established to analyze the risk factors associated with PH. RESULTS: There were 168 ELBWIs born during this period. A total of 160 infants were included, and 30 infants were diagnosed with PH. Risk factors including gestational age, small for gestational age, intubation in the delivery room, surfactant in the delivery room, repeated use of surfactant, higher FiO(2) during the first day, invasive ventilation during the first day and early onset sepsis (EOS) were associated with the occurrence of PH by univariate analysis. In the logistic regression model, EOS was found to be an independent risk factor for PH. The mortality and intraventricular hemorrhage rate of the group of ELBWIs with PH were significantly higher than those of the group of ELBWIs without PH. The rates of periventricular leukomalacia, moderate-to-severe bronchopulmonary dysplasia and severe retinopathy of prematurity, and the duration of the hospital stay were not significantly different between the PH and no-PH groups. CONCLUSIONS: Although PH did not extend hospital stay or increase the risk of bronchopulmonary dysplasia, it increased the mortality and intraventricular hemorrhage rate in ELBWIs. EOS was the independent risk factor for PH in ELBWIs. url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312118/ doi: 10.1007/s12519-019-00322-7 id: cord-010848-090yk40o author: Wang, Yan title: Continuous feeding versus intermittent bolus feeding for premature infants with low birth weight: a meta-analysis of randomized controlled trials date: 2019-10-28 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: BACKGROUND/OBJECTIVES: Clinical risks and advantages of both continuous feeding and intermittent feeding for preterm infants have been presented in previous studies. To determine the most appropriate feeding method for low-birth-weight infants, a meta-analysis was conducted. SUBJECTS/METHODS: Articles related to this topic were searched in PubMed, EMBASE, and Cochrane Library electronic database from the onset to May 2019. Heterogeneity analysis was performed with Chi-square and I(2) test. Pooled analysis was based on fixed effects model, if heterogeneity between the eligible studies was negligible (I(2) < 50%, P > 0.05). In contrast, a random effects model was carried out. The quality of including studies were evaluated by Cochrane assessment tool. RESULTS: A total of 1030 articles identified. Altogether, eight articles including 707 infants were included in final analysis based on eligibility criteria. In continuous feeding infants, time to achieving full feeds was longer (weight mean difference 0.98 (95% CI 0.26–1.71, P = 0.008) days) compared with intermittent feeding infants. Pooled analysis indicated there were no significant difference in other variables such as feeding intolerance, duration of hospitalization, days to regain birth weight, days to first successful oral feeding, duration of parenteral feeding, weight growth, length increment, head circumference growth, proven necrotizing enterocolitis, and probable necrotizing enterocolitis. In subgroup analysis for birth weight (<1000 g and >1000 g), we did not identify significant difference in time to full feeds, time to regain birth weight, and duration of hospitalization. CONCLUSIONS: Intermittent feeding may be more beneficial for low-birth weight infants, However, well-designed studies and evidenced-based clinical practice are required to determine the most appropriate feeding method for premature infants with low birth weight. url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222868/ doi: 10.1038/s41430-019-0522-x id: cord-022592-g7rmzsv5 author: Wynn, James L. title: Pathophysiology of Neonatal Sepsis date: 2016-07-06 words: 22148.0 sentences: 1302.0 pages: flesch: 39.0 cache: ./cache/cord-022592-g7rmzsv5.txt txt: ./txt/cord-022592-g7rmzsv5.txt summary: 14, 15, [27] [28] [29] [30] [31] [32] [33] Prematurity, low birth weight (especially infants weighing less than 1,000 g), male sex, a maternal vaginal culture positive for group B streptococcus (GBS), prolonged rupture of membranes, maternal intrapartum fever, and chorioamnionitis are strongly associated with an increased risk for early-onset sepsis. In addition to the initial inflammatory response including complement activation, molecular detection of PAMPs promotes IL-1β and IL-6 production, which in turn increases the production of multiple other innate proteins that possess valuable immune function and serve to reduce pathogen load. Very low birth weight preterm infants with early onset neonatal sepsis: the predominance of gram-negative infections continues in the National Institute of Child Health and Human Development Neonatal Research Network Very low birth weight preterm infants with early onset neonatal sepsis: the predominance of gram-negative infections continues in the National Institute of Child Health and Human Development Neonatal Research Network abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158364/ doi: 10.1016/b978-0-323-35214-7.00152-9 id: cord-005646-xhx9pzhj author: nan title: 2nd World Congress on Pediatric Intensive Care 1996 Rotterdam, The Netherlands, 23–26 June 1996 Abstracts of Oral Presentations, Posters and Nursing Programme date: 1996 words: 72031.0 sentences: 4734.0 pages: flesch: 56.0 cache: ./cache/cord-005646-xhx9pzhj.txt txt: ./txt/cord-005646-xhx9pzhj.txt summary: Aims and methods The aim of both a prospective and retrospective survey conducted in German pediatric intensive care units in 1993 was to accumulate data on the epidemiology, risk factors, natural history and treatment strategies in a large group of pediatric ARDS patients who were treated in the tt~ee year period from 1991 to 1993.All patients had acute bilateral alveolar infiltration of noncardiogenic origin and a pO2~iO2 ratio < 150mmHg. The influence of sex, underlying disease and single organ failure was analyzed using the Fischer''s exact test, the influence of additional organ failure on mortality was tested with the Cochran-Mantel-Haenszet statistics. abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095092/ doi: 10.1007/bf02316512 id: cord-014673-bb59z38j author: nan title: Abstracts 2019 der GNPI und DGPI: 45. Jahrestagung der Gesellschaft für Neonatologie und Pädiatrische Intensivmedizin gemeinsam mit der 27. Jahrestagung der Deutschen Gesellschaft für Pädiatrische Infektiologie, 23.–25. Mai 2019, Leipzig date: 2019-05-20 words: 14190.0 sentences: 1420.0 pages: flesch: 50.0 cache: ./cache/cord-014673-bb59z38j.txt txt: ./txt/cord-014673-bb59z38j.txt summary: Schlussfolgerung: Die aktuelle Studie zeigt, dass die Zebrafischlarve unter Zuhilfenahme innovativer mikroskopischer Technologien ein gutes Tier-Im Rahmen der europäischen ALBINO Studie wird die neuroprotektive Wirkung von Allopurinol bei Neugeborenen mit schwerer perinataler Aspyhxie zusätzlich zur Hypothermiebehandlung geprüft. They provide daily reference weights from birth to 42 weeks of postmenstrual age (PMA) Objective: The study aims to: 1) compare observed deviations of weight (∆W) from the GTC trajectory between cohorts and 2) analyze relationships between ∆W and short-term outcomes. Design/Methods: International multicohort study, including infants with a gestational age (GA) from 22 to 33 weeks with weekly or daily weight data from eight local cohorts (Austria, Germany, Sweden, Australia, Canada, USA) and the German Neonatal Network (birth weight (BW), 35 weeks PMA, discharge) during 2001 to 2017. Ein Säugling mit 3500 g und einer Compliance von 1,0 ml/mbar muss für 6 Background: We report on the latest progress made in the development of a lung assist device in the artificial placenta configuration. abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079845/ doi: 10.1007/s00112-019-0700-x id: cord-015172-hya08ch9 author: nan title: Abstracts der 41. Jahrestagung der Gesellschaft für Neonatologie und Pädiatrische Intensivmedizin date: 2015-05-20 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: nan url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096080/ doi: 10.1007/s00112-015-3359-y id: cord-253520-phtmgy6g author: nan title: Vaccination schedule for infants and COVID-19 date: 2020-05-23 words: 265.0 sentences: 26.0 pages: flesch: 64.0 cache: ./cache/cord-253520-phtmgy6g.txt txt: ./txt/cord-253520-phtmgy6g.txt summary: authors: nan title: Vaccination schedule for infants and COVID-19 Many parents have cancelled vaccination appointments for their infants as well as their older children. Fear of contagion in waiting rooms, doubts about the effects of vaccination on immunity in a pandemic period, and then containment, has led to a sharp decrease in vaccinations, mainly in infants. On April 1, 2020, the French Health Authority issued an opinion so that the vaccination schedule would not be delayed. The EPI-PHARE report on the use of city drugs during the Covid-19 period reveals that penta and hexavalent vaccines for infants have fallen by 23% and that deliveries of MMR and HPV vaccines have dropped by 50 to 70% during the last two weeks of March 2020 [1] . Infants must imperatively be vaccinated from the 2nd month, in order to acquire an effective protection as soon as possible against frequent and serious diseases at this age, particularly Usage des médicaments de ville en France durant l''épidémie de Covid-19 -point de situation à la fin mars 2020 abstract: nan url: https://api.elsevier.com/content/article/pii/S0001407920303150 doi: 10.1016/j.banm.2020.05.078 id: cord-286479-p9d78t6v author: nan title: NeoCORE Conference Abstracts date: 2020-07-09 words: nan sentences: nan pages: flesch: nan cache: txt: summary: abstract: nan url: https://doi.org/10.1007/s12098-020-03376-y doi: 10.1007/s12098-020-03376-y ==== make-pages.sh questions [ERIC WAS HERE] ==== make-pages.sh search /data-disk/reader-compute/reader-cord/bin/make-pages.sh: line 77: /data-disk/reader-compute/reader-cord/tmp/search.htm: No such file or directory Traceback (most recent call last): File "/data-disk/reader-compute/reader-cord/bin/tsv2htm-search.py", line 51, in with open( TEMPLATE, 'r' ) as handle : htm = handle.read() FileNotFoundError: [Errno 2] No such file or directory: '/data-disk/reader-compute/reader-cord/tmp/search.htm' ==== make-pages.sh topic modeling corpus Zipping study carrel