id	sid	tid	token	lemma	pos
cord-263862-zzys31e9	1	1	key	key	NN
cord-263862-zzys31e9	1	2	:	:	:
cord-263862-zzys31e9	1	3	cord-263862-zzys31e9	cord-263862-zzys31e9	CD
cord-263862-zzys31e9	2	1	authors	author	NNS
cord-263862-zzys31e9	2	2	:	:	:
cord-263862-zzys31e9	2	3	Ryan	Ryan	NNP
cord-263862-zzys31e9	2	4	,	,	,
cord-263862-zzys31e9	2	5	Elizabeth	Elizabeth	NNP
cord-263862-zzys31e9	2	6	J.	J.	NNP
cord-263862-zzys31e9	2	7	;	;	:
cord-263862-zzys31e9	2	8	Harenberg	Harenberg	NNP
cord-263862-zzys31e9	2	9	,	,	,
cord-263862-zzys31e9	2	10	Anke	Anke	NNP
cord-263862-zzys31e9	2	11	;	;	:
cord-263862-zzys31e9	2	12	Burdin	Burdin	NNP
cord-263862-zzys31e9	2	13	,	,	,
cord-263862-zzys31e9	2	14	Nicolas	Nicolas	NNP
cord-263862-zzys31e9	3	1	title	title	NN
cord-263862-zzys31e9	3	2	:	:	:
cord-263862-zzys31e9	4	1	The	the	DT
cord-263862-zzys31e9	4	2	Canarypox	Canarypox	NNP
cord-263862-zzys31e9	4	3	-	-	HYPH
cord-263862-zzys31e9	4	4	virus	virus	NN
cord-263862-zzys31e9	4	5	vaccine	vaccine	NN
cord-263862-zzys31e9	4	6	vector	vector	NN
cord-263862-zzys31e9	4	7	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	4	8	triggers	trigger	VBZ
cord-263862-zzys31e9	4	9	the	the	DT
cord-263862-zzys31e9	4	10	release	release	NN
cord-263862-zzys31e9	4	11	of	of	IN
cord-263862-zzys31e9	4	12	IFN	IFN	NNP
cord-263862-zzys31e9	4	13	-	-	HYPH
cord-263862-zzys31e9	4	14	γ	γ	NNP
cord-263862-zzys31e9	4	15	by	by	IN
cord-263862-zzys31e9	4	16	Natural	Natural	NNP
cord-263862-zzys31e9	4	17	Killer	Killer	NNP
cord-263862-zzys31e9	4	18	(	(	-LRB-
cord-263862-zzys31e9	4	19	NK	NK	NNP
cord-263862-zzys31e9	4	20	)	)	-RRB-
cord-263862-zzys31e9	4	21	cells	cell	NNS
cord-263862-zzys31e9	4	22	enhancing	enhance	VBG
cord-263862-zzys31e9	4	23	Th1	th1	CD
cord-263862-zzys31e9	4	24	polarization	polarization	NN
cord-263862-zzys31e9	4	25	date	date	NN
cord-263862-zzys31e9	4	26	:	:	:
cord-263862-zzys31e9	4	27	2007	2007	CD
cord-263862-zzys31e9	4	28	-	-	HYPH
cord-263862-zzys31e9	4	29	04	04	CD
cord-263862-zzys31e9	4	30	-	-	SYM
cord-263862-zzys31e9	4	31	30	30	CD
cord-263862-zzys31e9	4	32	journal	journal	NN
cord-263862-zzys31e9	4	33	:	:	:
cord-263862-zzys31e9	5	1	Vaccine	vaccine	NN
cord-263862-zzys31e9	5	2	DOI	doi	NN
cord-263862-zzys31e9	5	3	:	:	:
cord-263862-zzys31e9	6	1	10.1016	10.1016	CD
cord-263862-zzys31e9	6	2	/	/	SYM
cord-263862-zzys31e9	6	3	j.vaccine.2006.12.048	j.vaccine.2006.12.048	NNP
cord-263862-zzys31e9	6	4	sha	sha	NN
cord-263862-zzys31e9	6	5	:	:	:
cord-263862-zzys31e9	6	6	737b7ac2d2c39661379d73a47bdbf3d4d75eadf8	737b7ac2d2c39661379d73a47bdbf3d4d75eadf8	CD
cord-263862-zzys31e9	6	7	doc_id	doc_id	NNP
cord-263862-zzys31e9	6	8	:	:	:
cord-263862-zzys31e9	6	9	263862	263862	CD
cord-263862-zzys31e9	6	10	cord_uid	cord_uid	NNS
cord-263862-zzys31e9	6	11	:	:	:
cord-263862-zzys31e9	6	12	zzys31e9	zzys31e9	.
cord-263862-zzys31e9	7	1	We	-PRON-	PRP
cord-263862-zzys31e9	7	2	investigated	investigate	VBD
cord-263862-zzys31e9	7	3	the	the	DT
cord-263862-zzys31e9	7	4	mechanism	mechanism	NN
cord-263862-zzys31e9	7	5	by	by	IN
cord-263862-zzys31e9	7	6	which	which	WDT
cord-263862-zzys31e9	7	7	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	7	8	activates	activate	VBZ
cord-263862-zzys31e9	7	9	innate	innate	JJ
cord-263862-zzys31e9	7	10	immunity	immunity	NN
cord-263862-zzys31e9	7	11	.	.	.
cord-263862-zzys31e9	8	1	Combining	combine	VBG
cord-263862-zzys31e9	8	2	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	8	3	with	with	IN
cord-263862-zzys31e9	8	4	protein	protein	NN
cord-263862-zzys31e9	8	5	antigens	antigen	NNS
cord-263862-zzys31e9	8	6	significantly	significantly	RB
cord-263862-zzys31e9	8	7	augmented	augment	VBD
cord-263862-zzys31e9	8	8	antigen	antigen	NN
cord-263862-zzys31e9	8	9	-	-	HYPH
cord-263862-zzys31e9	8	10	specific	specific	JJ
cord-263862-zzys31e9	8	11	IgG2a	igg2a	JJ
cord-263862-zzys31e9	8	12	responses	response	NNS
cord-263862-zzys31e9	8	13	;	;	:
cord-263862-zzys31e9	8	14	this	this	DT
cord-263862-zzys31e9	8	15	was	be	VBD
cord-263862-zzys31e9	8	16	dependent	dependent	JJ
cord-263862-zzys31e9	8	17	on	on	IN
cord-263862-zzys31e9	8	18	the	the	DT
cord-263862-zzys31e9	8	19	presence	presence	NN
cord-263862-zzys31e9	8	20	of	of	IN
cord-263862-zzys31e9	8	21	bioactive	bioactive	JJ
cord-263862-zzys31e9	8	22	interferon	interferon	NN
cord-263862-zzys31e9	9	1	(	(	-LRB-
cord-263862-zzys31e9	9	2	IFN)-γ	ifn)-γ	NN
cord-263862-zzys31e9	9	3	.	.	.
cord-263862-zzys31e9	10	1	Immuno	immuno	JJ
cord-263862-zzys31e9	10	2	-	-	HYPH
cord-263862-zzys31e9	10	3	depletion	depletion	NN
cord-263862-zzys31e9	10	4	of	of	IN
cord-263862-zzys31e9	10	5	NK	NK	NNP
cord-263862-zzys31e9	10	6	cells	cell	NNS
cord-263862-zzys31e9	10	7	prior	prior	RB
cord-263862-zzys31e9	10	8	to	to	IN
cord-263862-zzys31e9	10	9	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	10	10	immunisation	immunisation	NN
cord-263862-zzys31e9	10	11	abrogated	abrogate	VBD
cord-263862-zzys31e9	10	12	IFN	IFN	NNP
cord-263862-zzys31e9	10	13	-	-	HYPH
cord-263862-zzys31e9	10	14	γ	γ	NN
cord-263862-zzys31e9	10	15	production	production	NN
cord-263862-zzys31e9	10	16	indicating	indicate	VBG
cord-263862-zzys31e9	10	17	that	that	IN
cord-263862-zzys31e9	10	18	they	-PRON-	PRP
cord-263862-zzys31e9	10	19	are	be	VBP
cord-263862-zzys31e9	10	20	the	the	DT
cord-263862-zzys31e9	10	21	main	main	JJ
cord-263862-zzys31e9	10	22	cellular	cellular	JJ
cord-263862-zzys31e9	10	23	source	source	NN
cord-263862-zzys31e9	10	24	of	of	IN
cord-263862-zzys31e9	10	25	early	early	JJ
cord-263862-zzys31e9	10	26	IFN	IFN	NNP
cord-263862-zzys31e9	10	27	-	-	HYPH
cord-263862-zzys31e9	10	28	γ	γ	NNP
cord-263862-zzys31e9	10	29	in	in	IN
cord-263862-zzys31e9	10	30	vivo	vivo	NNP
cord-263862-zzys31e9	10	31	.	.	.
cord-263862-zzys31e9	11	1	Murine	murine	JJ
cord-263862-zzys31e9	11	2	bone	bone	NN
cord-263862-zzys31e9	11	3	-	-	HYPH
cord-263862-zzys31e9	11	4	marrow	marrow	NN
cord-263862-zzys31e9	11	5	derived	derive	VBN
cord-263862-zzys31e9	11	6	dendritic	dendritic	JJ
cord-263862-zzys31e9	11	7	cells	cell	NNS
cord-263862-zzys31e9	11	8	(	(	-LRB-
cord-263862-zzys31e9	11	9	BMDCs	bmdc	NNS
cord-263862-zzys31e9	11	10	)	)	-RRB-
cord-263862-zzys31e9	11	11	cultured	culture	VBN
cord-263862-zzys31e9	11	12	in	in	IN
cord-263862-zzys31e9	11	13	the	the	DT
cord-263862-zzys31e9	11	14	presence	presence	NN
cord-263862-zzys31e9	11	15	of	of	IN
cord-263862-zzys31e9	11	16	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	11	17	secreted	secrete	VBD
cord-263862-zzys31e9	11	18	high	high	JJ
cord-263862-zzys31e9	11	19	levels	level	NNS
cord-263862-zzys31e9	11	20	of	of	IN
cord-263862-zzys31e9	11	21	the	the	DT
cord-263862-zzys31e9	11	22	chemokines	chemokine	NNS
cord-263862-zzys31e9	11	23	CXCL10	CXCL10	NNP
cord-263862-zzys31e9	11	24	and	and	CC
cord-263862-zzys31e9	11	25	CCL2	CCL2	NNP
cord-263862-zzys31e9	11	26	and	and	CC
cord-263862-zzys31e9	11	27	up	up	RB
cord-263862-zzys31e9	11	28	-	-	HYPH
cord-263862-zzys31e9	11	29	regulated	regulate	VBN
cord-263862-zzys31e9	11	30	expression	expression	NN
cord-263862-zzys31e9	11	31	of	of	IN
cord-263862-zzys31e9	11	32	the	the	DT
cord-263862-zzys31e9	11	33	maturation	maturation	NN
cord-263862-zzys31e9	11	34	markers	marker	NNS
cord-263862-zzys31e9	11	35	CD40	CD40	NNP
cord-263862-zzys31e9	11	36	,	,	,
cord-263862-zzys31e9	11	37	CD80	CD80	NNP
cord-263862-zzys31e9	11	38	and	and	CC
cord-263862-zzys31e9	11	39	CD86	CD86	NNP
cord-263862-zzys31e9	11	40	.	.	.
cord-263862-zzys31e9	12	1	Therefore	therefore	RB
cord-263862-zzys31e9	12	2	,	,	,
cord-263862-zzys31e9	12	3	we	-PRON-	PRP
cord-263862-zzys31e9	12	4	conclude	conclude	VBP
cord-263862-zzys31e9	12	5	that	that	IN
cord-263862-zzys31e9	12	6	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	12	7	acts	act	VBZ
cord-263862-zzys31e9	12	8	as	as	IN
cord-263862-zzys31e9	12	9	an	an	DT
cord-263862-zzys31e9	12	10	adjuvant	adjuvant	NN
cord-263862-zzys31e9	12	11	through	through	IN
cord-263862-zzys31e9	12	12	a	a	DT
cord-263862-zzys31e9	12	13	mechanism	mechanism	NN
cord-263862-zzys31e9	12	14	requiring	require	VBG
cord-263862-zzys31e9	12	15	NK	NK	NNP
cord-263862-zzys31e9	12	16	cell	cell	NN
cord-263862-zzys31e9	12	17	derived	derive	VBN
cord-263862-zzys31e9	12	18	IFN	IFN	NNP
cord-263862-zzys31e9	12	19	-	-	HYPH
cord-263862-zzys31e9	12	20	γ	γ	NNP
cord-263862-zzys31e9	12	21	,	,	,
cord-263862-zzys31e9	12	22	DC	DC	NNP
cord-263862-zzys31e9	12	23	activation	activation	NN
cord-263862-zzys31e9	12	24	and	and	CC
cord-263862-zzys31e9	12	25	chemokine	chemokine	NN
cord-263862-zzys31e9	12	26	secretion	secretion	NN
cord-263862-zzys31e9	12	27	.	.	.
cord-263862-zzys31e9	13	1	Adjuvants	adjuvant	NNS
cord-263862-zzys31e9	13	2	improve	improve	VBP
cord-263862-zzys31e9	13	3	the	the	DT
cord-263862-zzys31e9	13	4	adaptive	adaptive	JJ
cord-263862-zzys31e9	13	5	immune	immune	JJ
cord-263862-zzys31e9	13	6	response	response	NN
cord-263862-zzys31e9	13	7	to	to	IN
cord-263862-zzys31e9	13	8	coinjected	coinjected	JJ
cord-263862-zzys31e9	13	9	antigen	antigen	NN
cord-263862-zzys31e9	13	10	by	by	IN
cord-263862-zzys31e9	13	11	activating	activate	VBG
cord-263862-zzys31e9	13	12	innate	innate	JJ
cord-263862-zzys31e9	13	13	immunity	immunity	NN
cord-263862-zzys31e9	13	14	[	[	-LRB-
cord-263862-zzys31e9	13	15	1	1	CD
cord-263862-zzys31e9	13	16	]	]	-RRB-
cord-263862-zzys31e9	13	17	.	.	.
cord-263862-zzys31e9	14	1	In	in	IN
cord-263862-zzys31e9	14	2	spite	spite	NN
cord-263862-zzys31e9	14	3	of	of	IN
cord-263862-zzys31e9	14	4	intense	intense	JJ
cord-263862-zzys31e9	14	5	research	research	NN
cord-263862-zzys31e9	14	6	,	,	,
cord-263862-zzys31e9	14	7	there	there	EX
cord-263862-zzys31e9	14	8	is	be	VBZ
cord-263862-zzys31e9	14	9	still	still	RB
cord-263862-zzys31e9	14	10	a	a	DT
cord-263862-zzys31e9	14	11	limited	limited	JJ
cord-263862-zzys31e9	14	12	number	number	NN
cord-263862-zzys31e9	14	13	of	of	IN
cord-263862-zzys31e9	14	14	adjuvants	adjuvant	NNS
cord-263862-zzys31e9	14	15	available	available	JJ
cord-263862-zzys31e9	14	16	for	for	IN
cord-263862-zzys31e9	14	17	human	human	JJ
cord-263862-zzys31e9	14	18	use	use	NN
cord-263862-zzys31e9	14	19	,	,	,
cord-263862-zzys31e9	14	20	in	in	IN
cord-263862-zzys31e9	14	21	particular	particular	JJ
cord-263862-zzys31e9	14	22	to	to	TO
cord-263862-zzys31e9	14	23	enhance	enhance	VB
cord-263862-zzys31e9	14	24	the	the	DT
cord-263862-zzys31e9	14	25	induction	induction	NN
cord-263862-zzys31e9	14	26	of	of	IN
cord-263862-zzys31e9	14	27	the	the	DT
cord-263862-zzys31e9	14	28	polarized	polarized	JJ
cord-263862-zzys31e9	14	29	Th1	Th1	NNP
cord-263862-zzys31e9	14	30	response	response	NN
cord-263862-zzys31e9	14	31	required	require	VBN
cord-263862-zzys31e9	14	32	for	for	IN
cord-263862-zzys31e9	14	33	optimum	optimum	JJ
cord-263862-zzys31e9	14	34	protective	protective	JJ
cord-263862-zzys31e9	14	35	immunity	immunity	NN
cord-263862-zzys31e9	14	36	to	to	IN
cord-263862-zzys31e9	14	37	viral	viral	JJ
cord-263862-zzys31e9	14	38	infection	infection	NN
cord-263862-zzys31e9	14	39	and	and	CC
cord-263862-zzys31e9	14	40	for	for	IN
cord-263862-zzys31e9	14	41	cancer	cancer	NN
cord-263862-zzys31e9	14	42	therapy	therapy	NN
cord-263862-zzys31e9	14	43	[	[	-LRB-
cord-263862-zzys31e9	14	44	2	2	CD
cord-263862-zzys31e9	14	45	,	,	,
cord-263862-zzys31e9	14	46	3	3	CD
cord-263862-zzys31e9	14	47	]	]	-RRB-
cord-263862-zzys31e9	14	48	.	.	.
cord-263862-zzys31e9	15	1	Vaccination	vaccination	NN
cord-263862-zzys31e9	15	2	strategies	strategy	NNS
cord-263862-zzys31e9	15	3	based	base	VBN
cord-263862-zzys31e9	15	4	on	on	IN
cord-263862-zzys31e9	15	5	the	the	DT
cord-263862-zzys31e9	15	6	Canarypox	Canarypox	NNP
cord-263862-zzys31e9	15	7	-	-	HYPH
cord-263862-zzys31e9	15	8	virus	virus	NN
cord-263862-zzys31e9	15	9	vector	vector	NN
cord-263862-zzys31e9	15	10	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	15	11	have	have	VBP
cord-263862-zzys31e9	15	12	shown	show	VBN
cord-263862-zzys31e9	15	13	potential	potential	NN
cord-263862-zzys31e9	15	14	in	in	IN
cord-263862-zzys31e9	15	15	both	both	CC
cord-263862-zzys31e9	15	16	infectious	infectious	JJ
cord-263862-zzys31e9	15	17	disease	disease	NN
cord-263862-zzys31e9	15	18	[	[	-LRB-
cord-263862-zzys31e9	15	19	4	4	CD
cord-263862-zzys31e9	15	20	,	,	,
cord-263862-zzys31e9	15	21	5	5	CD
cord-263862-zzys31e9	15	22	]	]	-RRB-
cord-263862-zzys31e9	15	23	and	and	CC
cord-263862-zzys31e9	15	24	cancer	cancer	NN
cord-263862-zzys31e9	15	25	[	[	-LRB-
cord-263862-zzys31e9	15	26	6	6	CD
cord-263862-zzys31e9	15	27	]	]	-RRB-
cord-263862-zzys31e9	15	28	.	.	.
cord-263862-zzys31e9	16	1	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	16	2	,	,	,
cord-263862-zzys31e9	16	3	a	a	DT
cord-263862-zzys31e9	16	4	large	large	JJ
cord-263862-zzys31e9	16	5	DNA	dna	NN
cord-263862-zzys31e9	16	6	virus	virus	NN
cord-263862-zzys31e9	16	7	whose	whose	WP$
cord-263862-zzys31e9	16	8	replication	replication	NN
cord-263862-zzys31e9	16	9	is	be	VBZ
cord-263862-zzys31e9	16	10	confined	confine	VBN
cord-263862-zzys31e9	16	11	to	to	IN
cord-263862-zzys31e9	16	12	avian	avian	JJ
cord-263862-zzys31e9	16	13	hosts	host	NNS
cord-263862-zzys31e9	16	14	,	,	,
cord-263862-zzys31e9	16	15	has	have	VBZ
cord-263862-zzys31e9	16	16	a	a	DT
cord-263862-zzys31e9	16	17	good	good	JJ
cord-263862-zzys31e9	16	18	safety	safety	NN
cord-263862-zzys31e9	16	19	profile	profile	NN
cord-263862-zzys31e9	16	20	in	in	IN
cord-263862-zzys31e9	16	21	humans	human	NNS
cord-263862-zzys31e9	16	22	[	[	-LRB-
cord-263862-zzys31e9	16	23	5	5	CD
cord-263862-zzys31e9	16	24	]	]	-RRB-
cord-263862-zzys31e9	16	25	.	.	.
cord-263862-zzys31e9	17	1	Despite	despite	IN
cord-263862-zzys31e9	17	2	its	-PRON-	PRP$
cord-263862-zzys31e9	17	3	attenuated	attenuated	JJ
cord-263862-zzys31e9	17	4	nature	nature	NN
cord-263862-zzys31e9	17	5	,	,	,
cord-263862-zzys31e9	17	6	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	17	7	does	do	VBZ
cord-263862-zzys31e9	17	8	cause	cause	VB
cord-263862-zzys31e9	17	9	inflammation	inflammation	NN
cord-263862-zzys31e9	17	10	at	at	IN
cord-263862-zzys31e9	17	11	the	the	DT
cord-263862-zzys31e9	17	12	site	site	NN
cord-263862-zzys31e9	17	13	of	of	IN
cord-263862-zzys31e9	17	14	injection	injection	NN
cord-263862-zzys31e9	17	15	as	as	IN
cord-263862-zzys31e9	17	16	evidenced	evidence	VBN
cord-263862-zzys31e9	17	17	by	by	IN
cord-263862-zzys31e9	17	18	infiltration	infiltration	NN
cord-263862-zzys31e9	17	19	of	of	IN
cord-263862-zzys31e9	17	20	neutrophils	neutrophil	NNS
cord-263862-zzys31e9	17	21	[	[	-LRB-
cord-263862-zzys31e9	17	22	7	7	CD
cord-263862-zzys31e9	17	23	]	]	-RRB-
cord-263862-zzys31e9	17	24	.	.	.
cord-263862-zzys31e9	18	1	Furthermore	furthermore	RB
cord-263862-zzys31e9	18	2	,	,	,
cord-263862-zzys31e9	18	3	previous	previous	JJ
cord-263862-zzys31e9	18	4	reports	report	NNS
cord-263862-zzys31e9	18	5	show	show	VBP
cord-263862-zzys31e9	18	6	that	that	IN
cord-263862-zzys31e9	18	7	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	18	8	possesses	possess	VBZ
cord-263862-zzys31e9	18	9	adjuvant	adjuvant	NN
cord-263862-zzys31e9	18	10	activity	activity	NN
cord-263862-zzys31e9	18	11	[	[	-LRB-
cord-263862-zzys31e9	18	12	7	7	CD
cord-263862-zzys31e9	18	13	,	,	,
cord-263862-zzys31e9	18	14	8	8	CD
cord-263862-zzys31e9	18	15	]	]	-RRB-
cord-263862-zzys31e9	18	16	.	.	.
cord-263862-zzys31e9	19	1	In	in	IN
cord-263862-zzys31e9	19	2	this	this	DT
cord-263862-zzys31e9	19	3	study	study	NN
cord-263862-zzys31e9	19	4	,	,	,
cord-263862-zzys31e9	19	5	we	-PRON-	PRP
cord-263862-zzys31e9	19	6	confirm	confirm	VBP
cord-263862-zzys31e9	19	7	that	that	IN
cord-263862-zzys31e9	19	8	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	19	9	acts	act	VBZ
cord-263862-zzys31e9	19	10	as	as	IN
cord-263862-zzys31e9	19	11	an	an	DT
cord-263862-zzys31e9	19	12	adjuvant	adjuvant	NN
cord-263862-zzys31e9	19	13	,	,	,
cord-263862-zzys31e9	19	14	enhancing	enhance	VBG
cord-263862-zzys31e9	19	15	antigen	antigen	NN
cord-263862-zzys31e9	19	16	-	-	HYPH
cord-263862-zzys31e9	19	17	specific	specific	JJ
cord-263862-zzys31e9	19	18	IgG2a	IgG2a	NNP
cord-263862-zzys31e9	19	19	to	to	TO
cord-263862-zzys31e9	19	20	co	co	VB
cord-263862-zzys31e9	19	21	-	-	JJ
cord-263862-zzys31e9	19	22	injected	inject	VBN
cord-263862-zzys31e9	19	23	protein	protein	NN
cord-263862-zzys31e9	19	24	antigen	antigen	NN
cord-263862-zzys31e9	19	25	in	in	IN
cord-263862-zzys31e9	19	26	mice	mouse	NNS
cord-263862-zzys31e9	19	27	.	.	.
cord-263862-zzys31e9	20	1	Intra	intra	JJ
cord-263862-zzys31e9	20	2	-	-	JJ
cord-263862-zzys31e9	20	3	muscular	muscular	JJ
cord-263862-zzys31e9	20	4	(	(	-LRB-
cord-263862-zzys31e9	20	5	i.m	i.m	NNP
cord-263862-zzys31e9	20	6	.	.	.
cord-263862-zzys31e9	20	7	)	)	-RRB-
cord-263862-zzys31e9	20	8	injection	injection	NN
cord-263862-zzys31e9	20	9	of	of	IN
cord-263862-zzys31e9	20	10	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	20	11	increases	increase	VBZ
cord-263862-zzys31e9	20	12	levels	level	NNS
cord-263862-zzys31e9	20	13	of	of	IN
cord-263862-zzys31e9	20	14	circulating	circulate	VBG
cord-263862-zzys31e9	21	1	IFN-	IFN-	NNP
cord-263862-zzys31e9	21	2	␣	␣	NNP
cord-263862-zzys31e9	21	3	and	and	CC
cord-263862-zzys31e9	21	4	IFN-	IFN-	NNP
cord-263862-zzys31e9	21	5	␥	␥	NNP
cord-263862-zzys31e9	21	6	shortly	shortly	RB
cord-263862-zzys31e9	21	7	after	after	IN
cord-263862-zzys31e9	21	8	injection	injection	NN
cord-263862-zzys31e9	21	9	.	.	.
cord-263862-zzys31e9	22	1	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	22	2	enhanced	enhance	VBD
cord-263862-zzys31e9	22	3	antigen	antigen	NN
cord-263862-zzys31e9	22	4	-	-	HYPH
cord-263862-zzys31e9	22	5	specific	specific	JJ
cord-263862-zzys31e9	22	6	IgG2a	igg2a	JJ
cord-263862-zzys31e9	22	7	responses	response	NNS
cord-263862-zzys31e9	22	8	to	to	TO
cord-263862-zzys31e9	22	9	co	co	VB
cord-263862-zzys31e9	22	10	-	-	JJ
cord-263862-zzys31e9	22	11	injected	inject	VBN
cord-263862-zzys31e9	22	12	protein	protein	NN
cord-263862-zzys31e9	22	13	antigen	antigen	NN
cord-263862-zzys31e9	22	14	in	in	IN
cord-263862-zzys31e9	22	15	IFN-	IFN-	NNP
cord-263862-zzys31e9	22	16	␣	␣	NNP
cord-263862-zzys31e9	22	17	Receptor	Receptor	NNP
cord-263862-zzys31e9	22	18	knockout	knockout	NN
cord-263862-zzys31e9	22	19	(	(	-LRB-
cord-263862-zzys31e9	23	1	IFN-	IFN-	NNP
cord-263862-zzys31e9	24	1	␣	␣	NNP
cord-263862-zzys31e9	24	2	R	R	NNP
cord-263862-zzys31e9	24	3	−/−	−/−	NNP
cord-263862-zzys31e9	24	4	)	)	-RRB-
cord-263862-zzys31e9	25	1	mice	mouse	NNS
cord-263862-zzys31e9	25	2	but	but	CC
cord-263862-zzys31e9	25	3	not	not	RB
cord-263862-zzys31e9	26	1	IFN-	IFN-	NNP
cord-263862-zzys31e9	26	2	␥	␥	XX
cord-263862-zzys31e9	27	1	R	R	NNP
cord-263862-zzys31e9	27	2	−/−	−/−	NNP
cord-263862-zzys31e9	27	3	mice	mouse	NNS
cord-263862-zzys31e9	27	4	,	,	,
cord-263862-zzys31e9	27	5	indicating	indicate	VBG
cord-263862-zzys31e9	27	6	the	the	DT
cord-263862-zzys31e9	27	7	importance	importance	NN
cord-263862-zzys31e9	27	8	of	of	IN
cord-263862-zzys31e9	27	9	bioactive	bioactive	JJ
cord-263862-zzys31e9	27	10	IFN-	IFN-	NNP
cord-263862-zzys31e9	27	11	␥	␥	NNP
cord-263862-zzys31e9	27	12	in	in	IN
cord-263862-zzys31e9	27	13	mediating	mediate	VBG
cord-263862-zzys31e9	27	14	the	the	DT
cord-263862-zzys31e9	27	15	adjuvant	adjuvant	JJ
cord-263862-zzys31e9	27	16	effect	effect	NN
cord-263862-zzys31e9	27	17	of	of	IN
cord-263862-zzys31e9	27	18	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	27	19	.	.	.
cord-263862-zzys31e9	28	1	Immuno	immuno	JJ
cord-263862-zzys31e9	28	2	-	-	HYPH
cord-263862-zzys31e9	28	3	depletion	depletion	NN
cord-263862-zzys31e9	28	4	of	of	IN
cord-263862-zzys31e9	28	5	NK	NK	NNP
cord-263862-zzys31e9	28	6	cells	cell	NNS
cord-263862-zzys31e9	28	7	dramatically	dramatically	RB
cord-263862-zzys31e9	28	8	impaired	impair	VBD
cord-263862-zzys31e9	28	9	the	the	DT
cord-263862-zzys31e9	28	10	ability	ability	NN
cord-263862-zzys31e9	28	11	of	of	IN
cord-263862-zzys31e9	28	12	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	28	13	to	to	TO
cord-263862-zzys31e9	28	14	induce	induce	VB
cord-263862-zzys31e9	28	15	circulating	circulate	VBG
cord-263862-zzys31e9	28	16	IFN-	IFN-	NNP
cord-263862-zzys31e9	28	17	␥	␥	NNP
cord-263862-zzys31e9	28	18	,	,	,
cord-263862-zzys31e9	28	19	indicating	indicate	VBG
cord-263862-zzys31e9	28	20	that	that	IN
cord-263862-zzys31e9	28	21	these	these	DT
cord-263862-zzys31e9	28	22	cells	cell	NNS
cord-263862-zzys31e9	28	23	are	be	VBP
cord-263862-zzys31e9	28	24	the	the	DT
cord-263862-zzys31e9	28	25	major	major	JJ
cord-263862-zzys31e9	28	26	producer	producer	NN
cord-263862-zzys31e9	28	27	of	of	IN
cord-263862-zzys31e9	28	28	this	this	DT
cord-263862-zzys31e9	28	29	cytokine	cytokine	NN
cord-263862-zzys31e9	28	30	in	in	IN
cord-263862-zzys31e9	28	31	vivo	vivo	NN
cord-263862-zzys31e9	28	32	.	.	.
cord-263862-zzys31e9	29	1	A	a	DT
cord-263862-zzys31e9	29	2	previous	previous	JJ
cord-263862-zzys31e9	29	3	study	study	NN
cord-263862-zzys31e9	29	4	has	have	VBZ
cord-263862-zzys31e9	29	5	shown	show	VBN
cord-263862-zzys31e9	29	6	that	that	IN
cord-263862-zzys31e9	29	7	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	29	8	triggers	trigger	VBZ
cord-263862-zzys31e9	29	9	TNF-	TNF-	NNP
cord-263862-zzys31e9	30	1	␣	␣	NFP
cord-263862-zzys31e9	30	2	production	production	NN
cord-263862-zzys31e9	30	3	by	by	IN
cord-263862-zzys31e9	30	4	human	human	JJ
cord-263862-zzys31e9	30	5	DCs	dc	NNS
cord-263862-zzys31e9	30	6	[	[	-LRB-
cord-263862-zzys31e9	30	7	9	9	CD
cord-263862-zzys31e9	30	8	]	]	-RRB-
cord-263862-zzys31e9	30	9	.	.	.
cord-263862-zzys31e9	31	1	As	as	IN
cord-263862-zzys31e9	31	2	the	the	DT
cord-263862-zzys31e9	31	3	interaction	interaction	NN
cord-263862-zzys31e9	31	4	between	between	IN
cord-263862-zzys31e9	31	5	NK	NK	NNP
cord-263862-zzys31e9	31	6	and	and	CC
cord-263862-zzys31e9	31	7	DCs	DCs	NNP
cord-263862-zzys31e9	31	8	is	be	VBZ
cord-263862-zzys31e9	31	9	important	important	JJ
cord-263862-zzys31e9	31	10	for	for	IN
cord-263862-zzys31e9	31	11	the	the	DT
cord-263862-zzys31e9	31	12	induction	induction	NN
cord-263862-zzys31e9	31	13	of	of	IN
cord-263862-zzys31e9	31	14	the	the	DT
cord-263862-zzys31e9	31	15	innate	innate	JJ
cord-263862-zzys31e9	31	16	immune	immune	JJ
cord-263862-zzys31e9	31	17	response	response	NN
cord-263862-zzys31e9	31	18	[	[	-LRB-
cord-263862-zzys31e9	31	19	10	10	CD
cord-263862-zzys31e9	31	20	]	]	-RRB-
cord-263862-zzys31e9	32	1	we	-PRON-	PRP
cord-263862-zzys31e9	32	2	investigated	investigate	VBD
cord-263862-zzys31e9	32	3	the	the	DT
cord-263862-zzys31e9	32	4	effect	effect	NN
cord-263862-zzys31e9	32	5	of	of	IN
cord-263862-zzys31e9	32	6	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	32	7	exposure	exposure	NN
cord-263862-zzys31e9	32	8	on	on	IN
cord-263862-zzys31e9	32	9	murine	murine	JJ
cord-263862-zzys31e9	32	10	BMDC	BMDC	NNP
cord-263862-zzys31e9	32	11	regarding	regard	VBG
cord-263862-zzys31e9	32	12	maturation	maturation	NN
cord-263862-zzys31e9	32	13	and	and	CC
cord-263862-zzys31e9	32	14	cytokine	cytokine	NN
cord-263862-zzys31e9	32	15	production	production	NN
cord-263862-zzys31e9	32	16	.	.	.
cord-263862-zzys31e9	33	1	We	-PRON-	PRP
cord-263862-zzys31e9	33	2	show	show	VBP
cord-263862-zzys31e9	33	3	that	that	IN
cord-263862-zzys31e9	33	4	under	under	IN
cord-263862-zzys31e9	33	5	the	the	DT
cord-263862-zzys31e9	33	6	experimental	experimental	JJ
cord-263862-zzys31e9	33	7	conditions	condition	NNS
cord-263862-zzys31e9	33	8	we	-PRON-	PRP
cord-263862-zzys31e9	33	9	used	use	VBD
cord-263862-zzys31e9	33	10	,	,	,
cord-263862-zzys31e9	33	11	low	low	JJ
cord-263862-zzys31e9	33	12	levels	level	NNS
cord-263862-zzys31e9	33	13	of	of	IN
cord-263862-zzys31e9	33	14	apoptosis	apoptosis	NN
cord-263862-zzys31e9	33	15	were	be	VBD
cord-263862-zzys31e9	33	16	detected	detect	VBN
cord-263862-zzys31e9	33	17	,	,	,
cord-263862-zzys31e9	33	18	and	and	CC
cord-263862-zzys31e9	33	19	that	that	IN
cord-263862-zzys31e9	33	20	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	33	21	induces	induce	VBZ
cord-263862-zzys31e9	33	22	the	the	DT
cord-263862-zzys31e9	33	23	maturation	maturation	NN
cord-263862-zzys31e9	33	24	of	of	IN
cord-263862-zzys31e9	33	25	DCs	DCs	NNP
cord-263862-zzys31e9	33	26	(	(	-LRB-
cord-263862-zzys31e9	33	27	up	up	IN
cord-263862-zzys31e9	33	28	-	-	HYPH
cord-263862-zzys31e9	33	29	regulation	regulation	NN
cord-263862-zzys31e9	33	30	of	of	IN
cord-263862-zzys31e9	33	31	CD40	CD40	NNP
cord-263862-zzys31e9	33	32	,	,	,
cord-263862-zzys31e9	33	33	CD80	CD80	NNP
cord-263862-zzys31e9	33	34	and	and	CC
cord-263862-zzys31e9	33	35	CD86	CD86	NNP
cord-263862-zzys31e9	33	36	expression	expression	NN
cord-263862-zzys31e9	33	37	)	)	-RRB-
cord-263862-zzys31e9	33	38	and	and	CC
cord-263862-zzys31e9	33	39	the	the	DT
cord-263862-zzys31e9	33	40	production	production	NN
cord-263862-zzys31e9	33	41	of	of	IN
cord-263862-zzys31e9	33	42	low	low	JJ
cord-263862-zzys31e9	33	43	levels	level	NNS
cord-263862-zzys31e9	33	44	of	of	IN
cord-263862-zzys31e9	33	45	inflammatory	inflammatory	JJ
cord-263862-zzys31e9	33	46	cytokines	cytokine	NNS
cord-263862-zzys31e9	33	47	(	(	-LRB-
cord-263862-zzys31e9	34	1	IL-6	IL-6	NNP
cord-263862-zzys31e9	34	2	,	,	,
cord-263862-zzys31e9	34	3	TNF-	TNF-	NNP
cord-263862-zzys31e9	34	4	␣	␣	NN
cord-263862-zzys31e9	34	5	and	and	CC
cord-263862-zzys31e9	34	6	IL-12	IL-12	NNP
cord-263862-zzys31e9	34	7	)	)	-RRB-
cord-263862-zzys31e9	34	8	.	.	.
cord-263862-zzys31e9	35	1	However	however	RB
cord-263862-zzys31e9	35	2	,	,	,
cord-263862-zzys31e9	35	3	a	a	DT
cord-263862-zzys31e9	35	4	marked	marked	JJ
cord-263862-zzys31e9	35	5	increase	increase	NN
cord-263862-zzys31e9	35	6	in	in	IN
cord-263862-zzys31e9	35	7	the	the	DT
cord-263862-zzys31e9	35	8	secretion	secretion	NN
cord-263862-zzys31e9	35	9	of	of	IN
cord-263862-zzys31e9	35	10	the	the	DT
cord-263862-zzys31e9	35	11	chemokines	chemokine	NNS
cord-263862-zzys31e9	35	12	CXCL10	CXCL10	NNP
cord-263862-zzys31e9	35	13	and	and	CC
cord-263862-zzys31e9	35	14	CCL2	CCL2	NNP
cord-263862-zzys31e9	35	15	was	be	VBD
cord-263862-zzys31e9	35	16	observed	observe	VBN
cord-263862-zzys31e9	35	17	.	.	.
cord-263862-zzys31e9	36	1	Therefore	therefore	RB
cord-263862-zzys31e9	36	2	,	,	,
cord-263862-zzys31e9	36	3	this	this	DT
cord-263862-zzys31e9	36	4	leads	lead	VBZ
cord-263862-zzys31e9	36	5	us	-PRON-	PRP
cord-263862-zzys31e9	36	6	to	to	TO
cord-263862-zzys31e9	36	7	suggest	suggest	VB
cord-263862-zzys31e9	36	8	that	that	IN
cord-263862-zzys31e9	36	9	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	36	10	can	can	MD
cord-263862-zzys31e9	36	11	act	act	VB
cord-263862-zzys31e9	36	12	as	as	IN
cord-263862-zzys31e9	36	13	a	a	DT
cord-263862-zzys31e9	36	14	Th1	th1	NN
cord-263862-zzys31e9	36	15	polarizing	polarize	VBG
cord-263862-zzys31e9	36	16	adjuvant	adjuvant	NN
cord-263862-zzys31e9	36	17	by	by	IN
cord-263862-zzys31e9	36	18	inducing	induce	VBG
cord-263862-zzys31e9	36	19	local	local	JJ
cord-263862-zzys31e9	36	20	inflammation	inflammation	NN
cord-263862-zzys31e9	36	21	[	[	-LRB-
cord-263862-zzys31e9	36	22	7	7	CD
cord-263862-zzys31e9	36	23	]	]	-RRB-
cord-263862-zzys31e9	36	24	,	,	,
cord-263862-zzys31e9	36	25	resulting	result	VBG
cord-263862-zzys31e9	36	26	in	in	IN
cord-263862-zzys31e9	36	27	DC	DC	NNP
cord-263862-zzys31e9	36	28	maturation	maturation	NN
cord-263862-zzys31e9	36	29	and	and	CC
cord-263862-zzys31e9	36	30	chemokine	chemokine	NN
cord-263862-zzys31e9	36	31	production	production	NN
cord-263862-zzys31e9	36	32	which	which	WDT
cord-263862-zzys31e9	36	33	in	in	IN
cord-263862-zzys31e9	36	34	turn	turn	NN
cord-263862-zzys31e9	36	35	causes	cause	VBZ
cord-263862-zzys31e9	36	36	the	the	DT
cord-263862-zzys31e9	36	37	recruitment	recruitment	NN
cord-263862-zzys31e9	36	38	of	of	IN
cord-263862-zzys31e9	36	39	IFN-	IFN-	NNP
cord-263862-zzys31e9	36	40	␥	␥	NNP
cord-263862-zzys31e9	36	41	secreting	secrete	VBG
cord-263862-zzys31e9	36	42	NK	NK	NNP
cord-263862-zzys31e9	36	43	cells	cell	NNS
cord-263862-zzys31e9	36	44	.	.	.
cord-263862-zzys31e9	37	1	Understanding	understand	VBG
cord-263862-zzys31e9	37	2	the	the	DT
cord-263862-zzys31e9	37	3	mechanism	mechanism	NN
cord-263862-zzys31e9	37	4	of	of	IN
cord-263862-zzys31e9	37	5	adjuvant	adjuvant	JJ
cord-263862-zzys31e9	37	6	action	action	NN
cord-263862-zzys31e9	37	7	of	of	IN
cord-263862-zzys31e9	37	8	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	37	9	,	,	,
cord-263862-zzys31e9	37	10	will	will	MD
cord-263862-zzys31e9	37	11	allow	allow	VB
cord-263862-zzys31e9	37	12	more	more	RBR
cord-263862-zzys31e9	37	13	effective	effective	JJ
cord-263862-zzys31e9	37	14	targeting	targeting	NN
cord-263862-zzys31e9	37	15	of	of	IN
cord-263862-zzys31e9	37	16	the	the	DT
cord-263862-zzys31e9	37	17	desired	desire	VBN
cord-263862-zzys31e9	37	18	immune	immune	JJ
cord-263862-zzys31e9	37	19	response	response	NN
cord-263862-zzys31e9	37	20	by	by	IN
cord-263862-zzys31e9	37	21	taking	take	VBG
cord-263862-zzys31e9	37	22	advantage	advantage	NN
cord-263862-zzys31e9	37	23	of	of	IN
cord-263862-zzys31e9	37	24	the	the	DT
cord-263862-zzys31e9	37	25	fact	fact	NN
cord-263862-zzys31e9	37	26	that	that	IN
cord-263862-zzys31e9	37	27	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	37	28	can	can	MD
cord-263862-zzys31e9	37	29	be	be	VB
cord-263862-zzys31e9	37	30	manipulated	manipulate	VBN
cord-263862-zzys31e9	37	31	to	to	TO
cord-263862-zzys31e9	37	32	encode	encode	VB
cord-263862-zzys31e9	37	33	a	a	DT
cord-263862-zzys31e9	37	34	variety	variety	NN
cord-263862-zzys31e9	37	35	of	of	IN
cord-263862-zzys31e9	37	36	immunomodulatory	immunomodulatory	JJ
cord-263862-zzys31e9	37	37	transgenes	transgene	NNS
cord-263862-zzys31e9	37	38	,	,	,
cord-263862-zzys31e9	37	39	e.g.	e.g.	RB
cord-263862-zzys31e9	37	40	GM	GM	NNP
cord-263862-zzys31e9	37	41	-	-	HYPH
cord-263862-zzys31e9	37	42	CSF	CSF	NNP
cord-263862-zzys31e9	37	43	[	[	-LRB-
cord-263862-zzys31e9	37	44	11	11	CD
cord-263862-zzys31e9	37	45	]	]	-RRB-
cord-263862-zzys31e9	37	46	or	or	CC
cord-263862-zzys31e9	37	47	IL-12	IL-12	NNP
cord-263862-zzys31e9	37	48	[	[	-LRB-
cord-263862-zzys31e9	37	49	12	12	CD
cord-263862-zzys31e9	37	50	]	]	-RRB-
cord-263862-zzys31e9	37	51	that	that	WDT
cord-263862-zzys31e9	37	52	can	can	MD
cord-263862-zzys31e9	37	53	further	further	RB
cord-263862-zzys31e9	37	54	enhance	enhance	VB
cord-263862-zzys31e9	37	55	the	the	DT
cord-263862-zzys31e9	37	56	activation	activation	NN
cord-263862-zzys31e9	37	57	of	of	IN
cord-263862-zzys31e9	37	58	NK	NK	NNP
cord-263862-zzys31e9	37	59	cells	cell	NNS
cord-263862-zzys31e9	37	60	or	or	CC
cord-263862-zzys31e9	37	61	DCs	dc	NNS
cord-263862-zzys31e9	37	62	.	.	.
cord-263862-zzys31e9	38	1	Six	six	CD
cord-263862-zzys31e9	38	2	to	to	TO
cord-263862-zzys31e9	38	3	eight	eight	CD
cord-263862-zzys31e9	38	4	week	week	NN
cord-263862-zzys31e9	38	5	old	old	JJ
cord-263862-zzys31e9	38	6	female	female	JJ
cord-263862-zzys31e9	38	7	Balb	Balb	NNP
cord-263862-zzys31e9	38	8	/	/	SYM
cord-263862-zzys31e9	38	9	c	c	NNP
cord-263862-zzys31e9	38	10	ByJ	ByJ	NNP
cord-263862-zzys31e9	38	11	mice	mice	NNP
cord-263862-zzys31e9	38	12	(	(	-LRB-
cord-263862-zzys31e9	38	13	Charles	Charles	NNP
cord-263862-zzys31e9	38	14	River	River	NNP
cord-263862-zzys31e9	38	15	,	,	,
cord-263862-zzys31e9	38	16	Les	Les	NNP
cord-263862-zzys31e9	38	17	Oncins	Oncins	NNP
cord-263862-zzys31e9	38	18	,	,	,
cord-263862-zzys31e9	38	19	France	France	NNP
cord-263862-zzys31e9	38	20	)	)	-RRB-
cord-263862-zzys31e9	38	21	or	or	CC
cord-263862-zzys31e9	38	22	129	129	CD
cord-263862-zzys31e9	38	23	/	/	SYM
cord-263862-zzys31e9	38	24	Sv	Sv	NNP
cord-263862-zzys31e9	38	25	,	,	,
cord-263862-zzys31e9	38	26	IFN-	IFN-	NNP
cord-263862-zzys31e9	38	27	␣	␣	NNP
cord-263862-zzys31e9	38	28	receptor	receptor	NN
cord-263862-zzys31e9	38	29	knockout	knockout	NN
cord-263862-zzys31e9	38	30	and	and	CC
cord-263862-zzys31e9	38	31	IFN-	IFN-	NNP
cord-263862-zzys31e9	38	32	␥	␥	CD
cord-263862-zzys31e9	38	33	receptor	receptor	NN
cord-263862-zzys31e9	38	34	knockout	knockout	NN
cord-263862-zzys31e9	38	35	(	(	-LRB-
cord-263862-zzys31e9	38	36	B	b	NN
cord-263862-zzys31e9	38	37	+	+	CC
cord-263862-zzys31e9	38	38	K	K	NNP
cord-263862-zzys31e9	38	39	Universal	Universal	NNP
cord-263862-zzys31e9	38	40	,	,	,
cord-263862-zzys31e9	38	41	Hull	Hull	NNP
cord-263862-zzys31e9	38	42	,	,	,
cord-263862-zzys31e9	38	43	UK	UK	NNP
cord-263862-zzys31e9	38	44	)	)	-RRB-
cord-263862-zzys31e9	38	45	were	be	VBD
cord-263862-zzys31e9	38	46	used	use	VBN
cord-263862-zzys31e9	38	47	.	.	.
cord-263862-zzys31e9	39	1	Animals	animal	NNS
cord-263862-zzys31e9	39	2	were	be	VBD
cord-263862-zzys31e9	39	3	housed	house	VBN
cord-263862-zzys31e9	39	4	and	and	CC
cord-263862-zzys31e9	39	5	experiments	experiment	NNS
cord-263862-zzys31e9	39	6	carried	carry	VBN
cord-263862-zzys31e9	39	7	out	out	RP
cord-263862-zzys31e9	39	8	in	in	IN
cord-263862-zzys31e9	39	9	an	an	DT
cord-263862-zzys31e9	39	10	accredited	accredited	JJ
cord-263862-zzys31e9	39	11	facility	facility	NN
cord-263862-zzys31e9	39	12	under	under	IN
cord-263862-zzys31e9	39	13	the	the	DT
cord-263862-zzys31e9	39	14	guidelines	guideline	NNS
cord-263862-zzys31e9	39	15	of	of	IN
cord-263862-zzys31e9	39	16	Sanofi	Sanofi	NNP
cord-263862-zzys31e9	39	17	-	-	HYPH
cord-263862-zzys31e9	39	18	Pasteur	Pasteur	NNP
cord-263862-zzys31e9	39	19	's	's	POS
cord-263862-zzys31e9	39	20	local	local	JJ
cord-263862-zzys31e9	39	21	ethics	ethic	NNS
cord-263862-zzys31e9	39	22	committee	committee	NN
cord-263862-zzys31e9	39	23	.	.	.
cord-263862-zzys31e9	40	1	In	in	IN
cord-263862-zzys31e9	40	2	this	this	DT
cord-263862-zzys31e9	40	3	study	study	NN
cord-263862-zzys31e9	40	4	we	-PRON-	PRP
cord-263862-zzys31e9	40	5	used	use	VBD
cord-263862-zzys31e9	40	6	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	40	7	-	-	HYPH
cord-263862-zzys31e9	40	8	HIV	HIV	NNP
cord-263862-zzys31e9	40	9	,	,	,
cord-263862-zzys31e9	40	10	vCP1452	vcp1452	NN
cord-263862-zzys31e9	40	11	(	(	-LRB-
cord-263862-zzys31e9	40	12	Sanofi	Sanofi	NNP
cord-263862-zzys31e9	40	13	-	-	HYPH
cord-263862-zzys31e9	40	14	Pasteur	Pasteur	NNP
cord-263862-zzys31e9	40	15	,	,	,
cord-263862-zzys31e9	40	16	Marcy	Marcy	NNP
cord-263862-zzys31e9	40	17	l'Etoile	l'Etoile	NNP
cord-263862-zzys31e9	40	18	,	,	,
cord-263862-zzys31e9	40	19	France	France	NNP
cord-263862-zzys31e9	40	20	)	)	-RRB-
cord-263862-zzys31e9	40	21	a	a	DT
cord-263862-zzys31e9	40	22	recombinant	recombinant	JJ
cord-263862-zzys31e9	40	23	Canarypox	Canarypox	NNP
cord-263862-zzys31e9	40	24	vector	vector	NN
cord-263862-zzys31e9	40	25	that	that	WDT
cord-263862-zzys31e9	40	26	contains	contain	VBZ
cord-263862-zzys31e9	40	27	the	the	DT
cord-263862-zzys31e9	40	28	genes	gene	NNS
cord-263862-zzys31e9	40	29	for	for	IN
cord-263862-zzys31e9	40	30	HIV-1	HIV-1	NNP
cord-263862-zzys31e9	40	31	envelope	envelope	NN
cord-263862-zzys31e9	40	32	gp120	gp120	NNP
cord-263862-zzys31e9	40	33	(	(	-LRB-
cord-263862-zzys31e9	40	34	strain	strain	NN
cord-263862-zzys31e9	40	35	MN	MN	NNP
cord-263862-zzys31e9	40	36	)	)	-RRB-
cord-263862-zzys31e9	40	37	linked	link	VBN
cord-263862-zzys31e9	40	38	to	to	IN
cord-263862-zzys31e9	40	39	the	the	DT
cord-263862-zzys31e9	40	40	trans	trans	JJ
cord-263862-zzys31e9	40	41	-	-	NN
cord-263862-zzys31e9	40	42	membrane	membrane	JJ
cord-263862-zzys31e9	40	43	portion	portion	NN
cord-263862-zzys31e9	40	44	of	of	IN
cord-263862-zzys31e9	40	45	HIV-1	HIV-1	NNP
cord-263862-zzys31e9	40	46	gp41	gp41	NNP
cord-263862-zzys31e9	40	47	(	(	-LRB-
cord-263862-zzys31e9	40	48	strain	strain	NN
cord-263862-zzys31e9	40	49	LAI	LAI	NNP
cord-263862-zzys31e9	40	50	)	)	-RRB-
cord-263862-zzys31e9	40	51	,	,	,
cord-263862-zzys31e9	40	52	the	the	DT
cord-263862-zzys31e9	40	53	HIV-1	HIV-1	NNP
cord-263862-zzys31e9	40	54	LAI	LAI	NNP
cord-263862-zzys31e9	40	55	gag	gag	NN
cord-263862-zzys31e9	40	56	gene	gene	NN
cord-263862-zzys31e9	40	57	encoding	encoding	NN
cord-263862-zzys31e9	40	58	for	for	IN
cord-263862-zzys31e9	40	59	the	the	DT
cord-263862-zzys31e9	40	60	entire	entire	JJ
cord-263862-zzys31e9	40	61	gag	gag	NN
cord-263862-zzys31e9	40	62	protein	protein	NN
cord-263862-zzys31e9	40	63	,	,	,
cord-263862-zzys31e9	40	64	the	the	DT
cord-263862-zzys31e9	40	65	sequence	sequence	NN
cord-263862-zzys31e9	40	66	of	of	IN
cord-263862-zzys31e9	40	67	the	the	DT
cord-263862-zzys31e9	40	68	pol	pol	NN
cord-263862-zzys31e9	40	69	gene	gene	NN
cord-263862-zzys31e9	40	70	encoding	encode	VBG
cord-263862-zzys31e9	40	71	the	the	DT
cord-263862-zzys31e9	40	72	protease	protease	NN
cord-263862-zzys31e9	40	73	,	,	,
cord-263862-zzys31e9	40	74	and	and	CC
cord-263862-zzys31e9	40	75	a	a	DT
cord-263862-zzys31e9	40	76	synthetic	synthetic	JJ
cord-263862-zzys31e9	40	77	polynucleotide	polynucleotide	NN
cord-263862-zzys31e9	40	78	encompassing	encompass	VBG
cord-263862-zzys31e9	40	79	several	several	JJ
cord-263862-zzys31e9	40	80	known	know	VBN
cord-263862-zzys31e9	40	81	human	human	JJ
cord-263862-zzys31e9	40	82	CTL	CTL	NNP
cord-263862-zzys31e9	40	83	epitopes	epitope	NNS
cord-263862-zzys31e9	40	84	from	from	IN
cord-263862-zzys31e9	40	85	the	the	DT
cord-263862-zzys31e9	40	86	nef	nef	NNP
cord-263862-zzys31e9	40	87	and	and	CC
cord-263862-zzys31e9	40	88	pol	pol	NNP
cord-263862-zzys31e9	40	89	gene	gene	NN
cord-263862-zzys31e9	40	90	products	product	NNS
cord-263862-zzys31e9	40	91	.	.	.
cord-263862-zzys31e9	41	1	It	-PRON-	PRP
cord-263862-zzys31e9	41	2	also	also	RB
cord-263862-zzys31e9	41	3	contains	contain	VBZ
cord-263862-zzys31e9	41	4	sequences	sequence	NNS
cord-263862-zzys31e9	41	5	encoding	encode	VBG
cord-263862-zzys31e9	41	6	the	the	DT
cord-263862-zzys31e9	41	7	E3L	e3l	NN
cord-263862-zzys31e9	41	8	and	and	CC
cord-263862-zzys31e9	41	9	K3L	k3l	CD
cord-263862-zzys31e9	41	10	vaccinia	vaccinia	NN
cord-263862-zzys31e9	41	11	virus	virus	NN
cord-263862-zzys31e9	41	12	proteins	protein	NNS
cord-263862-zzys31e9	41	13	in	in	IN
cord-263862-zzys31e9	41	14	the	the	DT
cord-263862-zzys31e9	41	15	C6	C6	NNP
cord-263862-zzys31e9	41	16	site	site	NN
cord-263862-zzys31e9	41	17	.	.	.
cord-263862-zzys31e9	42	1	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	42	2	Placebo	Placebo	NNP
cord-263862-zzys31e9	42	3	(	(	-LRB-
cord-263862-zzys31e9	42	4	Sanofi	Sanofi	NNP
cord-263862-zzys31e9	42	5	-	-	HYPH
cord-263862-zzys31e9	42	6	Pasteur	Pasteur	NNP
cord-263862-zzys31e9	42	7	)	)	-RRB-
cord-263862-zzys31e9	42	8	contains	contain	VBZ
cord-263862-zzys31e9	42	9	a	a	DT
cord-263862-zzys31e9	42	10	mixture	mixture	NN
cord-263862-zzys31e9	42	11	of	of	IN
cord-263862-zzys31e9	42	12	10	10	CD
cord-263862-zzys31e9	42	13	mM	mM	NNP
cord-263862-zzys31e9	42	14	Tris	Tris	NNP
cord-263862-zzys31e9	42	15	-	-	HYPH
cord-263862-zzys31e9	42	16	HCl	HCl	NNP
cord-263862-zzys31e9	42	17	buffer	buffer	NN
cord-263862-zzys31e9	42	18	pH	pH	NNP
cord-263862-zzys31e9	42	19	9.0	9.0	CD
cord-263862-zzys31e9	42	20	,	,	,
cord-263862-zzys31e9	42	21	virus	virus	NN
cord-263862-zzys31e9	42	22	stabilizer	stabilizer	NN
cord-263862-zzys31e9	42	23	and	and	CC
cord-263862-zzys31e9	42	24	freeze	freeze	NN
cord-263862-zzys31e9	42	25	-	-	HYPH
cord-263862-zzys31e9	42	26	drying	dry	VBG
cord-263862-zzys31e9	42	27	medium	medium	NN
cord-263862-zzys31e9	42	28	.	.	.
cord-263862-zzys31e9	43	1	Both	both	DT
cord-263862-zzys31e9	43	2	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	43	3	and	and	CC
cord-263862-zzys31e9	43	4	Placebo	Placebo	NNP
cord-263862-zzys31e9	43	5	were	be	VBD
cord-263862-zzys31e9	43	6	re	re	VBN
cord-263862-zzys31e9	43	7	-	-	VBN
cord-263862-zzys31e9	43	8	constituted	constitute	VBN
cord-263862-zzys31e9	43	9	in	in	IN
cord-263862-zzys31e9	43	10	sterile	sterile	JJ
cord-263862-zzys31e9	43	11	0.9	0.9	CD
cord-263862-zzys31e9	43	12	%	%	NN
cord-263862-zzys31e9	43	13	saline	saline	NN
cord-263862-zzys31e9	43	14	prior	prior	RB
cord-263862-zzys31e9	43	15	to	to	IN
cord-263862-zzys31e9	43	16	injection	injection	NN
cord-263862-zzys31e9	43	17	.	.	.
cord-263862-zzys31e9	44	1	Recombinant	recombinant	JJ
cord-263862-zzys31e9	44	2	HIV	HIV	NNP
cord-263862-zzys31e9	44	3	Tat	Tat	NNP
cord-263862-zzys31e9	44	4	protein	protein	NN
cord-263862-zzys31e9	44	5	from	from	IN
cord-263862-zzys31e9	44	6	the	the	DT
cord-263862-zzys31e9	44	7	HIV-1	HIV-1	NNP
cord-263862-zzys31e9	44	8	IIIB	IIIB	NNP
cord-263862-zzys31e9	44	9	isolate	isolate	VBP
cord-263862-zzys31e9	44	10	and	and	CC
cord-263862-zzys31e9	44	11	glycoprotein	glycoprotein	NN
cord-263862-zzys31e9	44	12	B	B	NNP
cord-263862-zzys31e9	44	13	(	(	-LRB-
cord-263862-zzys31e9	44	14	gB	gB	NNP
cord-263862-zzys31e9	44	15	)	)	-RRB-
cord-263862-zzys31e9	44	16	from	from	IN
cord-263862-zzys31e9	44	17	cytomegalovirus	cytomegalovirus	NNP
cord-263862-zzys31e9	44	18	(	(	-LRB-
cord-263862-zzys31e9	44	19	CMV	CMV	NNP
cord-263862-zzys31e9	44	20	)	)	-RRB-
cord-263862-zzys31e9	44	21	were	be	VBD
cord-263862-zzys31e9	44	22	purified	purify	VBN
cord-263862-zzys31e9	44	23	from	from	IN
cord-263862-zzys31e9	44	24	bacterial	bacterial	JJ
cord-263862-zzys31e9	44	25	culture	culture	NN
cord-263862-zzys31e9	44	26	at	at	IN
cord-263862-zzys31e9	44	27	Sanofi	Sanofi	NNP
cord-263862-zzys31e9	44	28	-	-	HYPH
cord-263862-zzys31e9	44	29	Pasteur	Pasteur	NNP
cord-263862-zzys31e9	44	30	.	.	.
cord-263862-zzys31e9	45	1	All	all	DT
cord-263862-zzys31e9	45	2	vaccines	vaccine	NNS
cord-263862-zzys31e9	45	3	used	use	VBN
cord-263862-zzys31e9	45	4	in	in	IN
cord-263862-zzys31e9	45	5	this	this	DT
cord-263862-zzys31e9	45	6	study	study	NN
cord-263862-zzys31e9	45	7	were	be	VBD
cord-263862-zzys31e9	45	8	clinical	clinical	JJ
cord-263862-zzys31e9	45	9	grade	grade	NN
cord-263862-zzys31e9	45	10	and	and	CC
cord-263862-zzys31e9	45	11	were	be	VBD
cord-263862-zzys31e9	45	12	verified	verify	VBN
cord-263862-zzys31e9	45	13	to	to	TO
cord-263862-zzys31e9	45	14	be	be	VB
cord-263862-zzys31e9	45	15	free	free	JJ
cord-263862-zzys31e9	45	16	of	of	IN
cord-263862-zzys31e9	45	17	lipopolysaccharide	lipopolysaccharide	NN
cord-263862-zzys31e9	45	18	(	(	-LRB-
cord-263862-zzys31e9	45	19	LPS	LPS	NNP
cord-263862-zzys31e9	45	20	)	)	-RRB-
cord-263862-zzys31e9	45	21	and	and	CC
cord-263862-zzys31e9	45	22	other	other	JJ
cord-263862-zzys31e9	45	23	impurities	impurity	NNS
cord-263862-zzys31e9	45	24	.	.	.
cord-263862-zzys31e9	46	1	Groups	group	NNS
cord-263862-zzys31e9	46	2	of	of	IN
cord-263862-zzys31e9	46	3	10	10	CD
cord-263862-zzys31e9	46	4	Balb	Balb	NNP
cord-263862-zzys31e9	46	5	/	/	SYM
cord-263862-zzys31e9	46	6	c	c	NN
cord-263862-zzys31e9	46	7	,	,	,
cord-263862-zzys31e9	46	8	129	129	CD
cord-263862-zzys31e9	46	9	/	/	SYM
cord-263862-zzys31e9	46	10	Sv	Sv	NNP
cord-263862-zzys31e9	46	11	,	,	,
cord-263862-zzys31e9	46	12	IFN-	IFN-	NNP
cord-263862-zzys31e9	46	13	␣	␣	NN
cord-263862-zzys31e9	46	14	R	r	NN
cord-263862-zzys31e9	46	15	knockout	knockout	NN
cord-263862-zzys31e9	46	16	,	,	,
cord-263862-zzys31e9	46	17	or	or	CC
cord-263862-zzys31e9	46	18	IFN-	IFN-	NNP
cord-263862-zzys31e9	46	19	␥	␥	NNP
cord-263862-zzys31e9	46	20	R	r	NN
cord-263862-zzys31e9	46	21	knockout	knockout	NN
cord-263862-zzys31e9	46	22	mice	mouse	NNS
cord-263862-zzys31e9	46	23	were	be	VBD
cord-263862-zzys31e9	46	24	immunised	immunise	VBN
cord-263862-zzys31e9	46	25	i.m	i.m	NNP
cord-263862-zzys31e9	46	26	.	.	.
cord-263862-zzys31e9	47	1	in	in	IN
cord-263862-zzys31e9	47	2	the	the	DT
cord-263862-zzys31e9	47	3	quadriceps	quadriceps	NN
cord-263862-zzys31e9	47	4	following	follow	VBG
cord-263862-zzys31e9	47	5	anaesthesia	anaesthesia	NN
cord-263862-zzys31e9	47	6	with	with	IN
cord-263862-zzys31e9	47	7	Imalgene	Imalgene	NNP
cord-263862-zzys31e9	47	8	500	500	CD
cord-263862-zzys31e9	48	1	(	(	-LRB-
cord-263862-zzys31e9	48	2	Merial	Merial	NNP
cord-263862-zzys31e9	48	3	,	,	,
cord-263862-zzys31e9	48	4	Lyon	Lyon	NNP
cord-263862-zzys31e9	48	5	,	,	,
cord-263862-zzys31e9	48	6	France	France	NNP
cord-263862-zzys31e9	48	7	)	)	-RRB-
cord-263862-zzys31e9	48	8	with	with	IN
cord-263862-zzys31e9	48	9	either	either	CC
cord-263862-zzys31e9	48	10	gB	gB	NNP
cord-263862-zzys31e9	48	11	(	(	-LRB-
cord-263862-zzys31e9	48	12	2	2	CD
cord-263862-zzys31e9	48	13	g	g	NN
cord-263862-zzys31e9	48	14	/	/	SYM
cord-263862-zzys31e9	48	15	dose	dose	NN
cord-263862-zzys31e9	48	16	)	)	-RRB-
cord-263862-zzys31e9	48	17	,	,	.
cord-263862-zzys31e9	49	1	Tat	tat	NN
cord-263862-zzys31e9	49	2	(	(	-LRB-
cord-263862-zzys31e9	49	3	20	20	CD
cord-263862-zzys31e9	49	4	g	g	NN
cord-263862-zzys31e9	49	5	/	/	SYM
cord-263862-zzys31e9	49	6	dose	dose	NN
cord-263862-zzys31e9	49	7	)	)	-RRB-
cord-263862-zzys31e9	49	8	,	,	,
cord-263862-zzys31e9	49	9	alone	alone	RB
cord-263862-zzys31e9	49	10	or	or	CC
cord-263862-zzys31e9	49	11	in	in	IN
cord-263862-zzys31e9	49	12	combination	combination	NN
cord-263862-zzys31e9	49	13	with	with	IN
cord-263862-zzys31e9	49	14	Placebo	Placebo	NNP
cord-263862-zzys31e9	49	15	or	or	CC
cord-263862-zzys31e9	49	16	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	49	17	(	(	-LRB-
cord-263862-zzys31e9	49	18	1/10	1/10	CD
cord-263862-zzys31e9	49	19	human	human	JJ
cord-263862-zzys31e9	49	20	dose	dose	NN
cord-263862-zzys31e9	49	21	)	)	-RRB-
cord-263862-zzys31e9	49	22	.	.	.
cord-263862-zzys31e9	50	1	Mice	mouse	NNS
cord-263862-zzys31e9	50	2	were	be	VBD
cord-263862-zzys31e9	50	3	boosted	boost	VBN
cord-263862-zzys31e9	50	4	at	at	IN
cord-263862-zzys31e9	50	5	day	day	NN
cord-263862-zzys31e9	50	6	21	21	CD
cord-263862-zzys31e9	50	7	and	and	CC
cord-263862-zzys31e9	50	8	serum	serum	NN
cord-263862-zzys31e9	50	9	and	and	CC
cord-263862-zzys31e9	50	10	spleen	spleen	NN
cord-263862-zzys31e9	50	11	samples	sample	NNS
cord-263862-zzys31e9	50	12	taken	take	VBN
cord-263862-zzys31e9	50	13	at	at	IN
cord-263862-zzys31e9	50	14	day	day	NN
cord-263862-zzys31e9	50	15	35	35	CD
cord-263862-zzys31e9	50	16	.	.	.
cord-263862-zzys31e9	51	1	Anti	Anti	NNP
cord-263862-zzys31e9	51	2	-	-	NNP
cord-263862-zzys31e9	51	3	Tat	Tat	NNP
cord-263862-zzys31e9	51	4	and	and	CC
cord-263862-zzys31e9	51	5	gB	gB	NNP
cord-263862-zzys31e9	51	6	antibody	antibody	NN
cord-263862-zzys31e9	51	7	titres	titre	NNS
cord-263862-zzys31e9	51	8	and	and	CC
cord-263862-zzys31e9	51	9	specific	specific	JJ
cord-263862-zzys31e9	51	10	cellular	cellular	JJ
cord-263862-zzys31e9	51	11	responses	response	NNS
cord-263862-zzys31e9	51	12	were	be	VBD
cord-263862-zzys31e9	51	13	then	then	RB
cord-263862-zzys31e9	51	14	analysed	analyse	VBN
cord-263862-zzys31e9	51	15	as	as	IN
cord-263862-zzys31e9	51	16	described	describe	VBN
cord-263862-zzys31e9	51	17	below	below	RB
cord-263862-zzys31e9	51	18	.	.	.
cord-263862-zzys31e9	52	1	Maxi	Maxi	NNP
cord-263862-zzys31e9	52	2	-	-	HYPH
cord-263862-zzys31e9	52	3	Sorp	Sorp	NNP
cord-263862-zzys31e9	52	4	ELISA	ELISA	NNP
cord-263862-zzys31e9	52	5	plates	plate	NNS
cord-263862-zzys31e9	52	6	(	(	-LRB-
cord-263862-zzys31e9	52	7	Nunc	Nunc	NNP
cord-263862-zzys31e9	52	8	,	,	,
cord-263862-zzys31e9	52	9	Wiesbaden	Wiesbaden	NNP
cord-263862-zzys31e9	52	10	,	,	,
cord-263862-zzys31e9	52	11	Germany	Germany	NNP
cord-263862-zzys31e9	52	12	)	)	-RRB-
cord-263862-zzys31e9	52	13	were	be	VBD
cord-263862-zzys31e9	52	14	coated	coat	VBN
cord-263862-zzys31e9	52	15	with	with	IN
cord-263862-zzys31e9	52	16	1	1	CD
cord-263862-zzys31e9	52	17	g	g	NN
cord-263862-zzys31e9	52	18	/	/	SYM
cord-263862-zzys31e9	52	19	ml	ml	NN
cord-263862-zzys31e9	52	20	of	of	IN
cord-263862-zzys31e9	52	21	either	either	DT
cord-263862-zzys31e9	52	22	Tat	Tat	NNP
cord-263862-zzys31e9	52	23	or	or	CC
cord-263862-zzys31e9	52	24	gB	gB	NNP
cord-263862-zzys31e9	52	25	in	in	IN
cord-263862-zzys31e9	52	26	PBS	PBS	NNP
cord-263862-zzys31e9	52	27	overnight	overnight	RB
cord-263862-zzys31e9	52	28	at	at	IN
cord-263862-zzys31e9	52	29	4	4	CD
cord-263862-zzys31e9	53	1	•	•	NNP
cord-263862-zzys31e9	54	1	C.	C.	NNP
cord-263862-zzys31e9	54	2	Plates	plate	NNS
cord-263862-zzys31e9	54	3	were	be	VBD
cord-263862-zzys31e9	54	4	blocked	block	VBN
cord-263862-zzys31e9	54	5	with	with	IN
cord-263862-zzys31e9	54	6	1	1	CD
cord-263862-zzys31e9	54	7	%	%	NN
cord-263862-zzys31e9	54	8	non	non	JJ
cord-263862-zzys31e9	54	9	-	-	JJ
cord-263862-zzys31e9	54	10	fat	fat	JJ
cord-263862-zzys31e9	54	11	milk	milk	NN
cord-263862-zzys31e9	54	12	(	(	-LRB-
cord-263862-zzys31e9	54	13	Gibco	Gibco	NNP
cord-263862-zzys31e9	54	14	,	,	,
cord-263862-zzys31e9	54	15	Paisley	Paisley	NNP
cord-263862-zzys31e9	54	16	,	,	,
cord-263862-zzys31e9	54	17	UK	UK	NNP
cord-263862-zzys31e9	54	18	)	)	-RRB-
cord-263862-zzys31e9	54	19	at	at	IN
cord-263862-zzys31e9	54	20	37	37	CD
cord-263862-zzys31e9	54	21	•	•	NN
cord-263862-zzys31e9	54	22	C	C	NNP
cord-263862-zzys31e9	54	23	for	for	IN
cord-263862-zzys31e9	54	24	1	1	CD
cord-263862-zzys31e9	54	25	h	h	NN
cord-263862-zzys31e9	54	26	,	,	,
cord-263862-zzys31e9	54	27	after	after	IN
cord-263862-zzys31e9	54	28	washing	wash	VBG
cord-263862-zzys31e9	54	29	serial	serial	JJ
cord-263862-zzys31e9	54	30	dilutions	dilution	NNS
cord-263862-zzys31e9	54	31	of	of	IN
cord-263862-zzys31e9	54	32	serum	serum	NN
cord-263862-zzys31e9	54	33	samples	sample	NNS
cord-263862-zzys31e9	54	34	and	and	CC
cord-263862-zzys31e9	54	35	standards	standard	NNS
cord-263862-zzys31e9	54	36	were	be	VBD
cord-263862-zzys31e9	54	37	added	add	VBN
cord-263862-zzys31e9	54	38	for	for	IN
cord-263862-zzys31e9	54	39	1	1	CD
cord-263862-zzys31e9	54	40	h	h	NN
cord-263862-zzys31e9	54	41	at	at	IN
cord-263862-zzys31e9	54	42	37	37	CD
cord-263862-zzys31e9	54	43	•	•	NN
cord-263862-zzys31e9	54	44	C.	C.	NNP
cord-263862-zzys31e9	54	45	Plates	plate	NNS
cord-263862-zzys31e9	54	46	were	be	VBD
cord-263862-zzys31e9	54	47	then	then	RB
cord-263862-zzys31e9	54	48	washed	wash	VBN
cord-263862-zzys31e9	54	49	and	and	CC
cord-263862-zzys31e9	54	50	the	the	DT
cord-263862-zzys31e9	54	51	detection	detection	NN
cord-263862-zzys31e9	54	52	antibody	antibody	NN
cord-263862-zzys31e9	54	53	,	,	,
cord-263862-zzys31e9	54	54	goat	goat	NN
cord-263862-zzys31e9	54	55	-	-	HYPH
cord-263862-zzys31e9	54	56	anti	anti	JJ
cord-263862-zzys31e9	54	57	-	-	JJ
cord-263862-zzys31e9	54	58	mouse	mouse	JJ
cord-263862-zzys31e9	54	59	IgG	IgG	NNP
cord-263862-zzys31e9	54	60	-	-	HYPH
cord-263862-zzys31e9	54	61	HRP	HRP	NNP
cord-263862-zzys31e9	54	62	(	(	-LRB-
cord-263862-zzys31e9	54	63	Jackson	Jackson	NNP
cord-263862-zzys31e9	54	64	ImmunoResearch	ImmunoResearch	NNP
cord-263862-zzys31e9	54	65	Laboratories	Laboratories	NNP
cord-263862-zzys31e9	54	66	,	,	,
cord-263862-zzys31e9	54	67	Inc.	Inc.	NNP
cord-263862-zzys31e9	54	68	,	,	,
cord-263862-zzys31e9	54	69	West	West	NNP
cord-263862-zzys31e9	54	70	Grove	Grove	NNP
cord-263862-zzys31e9	54	71	,	,	,
cord-263862-zzys31e9	54	72	PA	PA	NNP
cord-263862-zzys31e9	54	73	)	)	-RRB-
cord-263862-zzys31e9	54	74	was	be	VBD
cord-263862-zzys31e9	54	75	added	add	VBN
cord-263862-zzys31e9	54	76	for	for	IN
cord-263862-zzys31e9	54	77	a	a	DT
cord-263862-zzys31e9	54	78	further	further	JJ
cord-263862-zzys31e9	54	79	hour	hour	NN
cord-263862-zzys31e9	54	80	at	at	IN
cord-263862-zzys31e9	54	81	37	37	CD
cord-263862-zzys31e9	54	82	•	•	NN
cord-263862-zzys31e9	54	83	C.	C.	NNP
cord-263862-zzys31e9	54	84	Plates	plate	NNS
cord-263862-zzys31e9	54	85	were	be	VBD
cord-263862-zzys31e9	54	86	washed	wash	VBN
cord-263862-zzys31e9	54	87	,	,	,
cord-263862-zzys31e9	54	88	and	and	CC
cord-263862-zzys31e9	54	89	a	a	DT
cord-263862-zzys31e9	54	90	tetramethlybenzidine	tetramethlybenzidine	JJ
cord-263862-zzys31e9	54	91	substrate	substrate	NN
cord-263862-zzys31e9	54	92	solution	solution	NN
cord-263862-zzys31e9	54	93	added	add	VBN
cord-263862-zzys31e9	54	94	(	(	-LRB-
cord-263862-zzys31e9	54	95	Tebu	Tebu	NNP
cord-263862-zzys31e9	54	96	Bio	Bio	NNP
cord-263862-zzys31e9	54	97	-	-	HYPH
cord-263862-zzys31e9	54	98	Labs	Labs	NNP
cord-263862-zzys31e9	54	99	,	,	,
cord-263862-zzys31e9	54	100	Le	Le	NNP
cord-263862-zzys31e9	54	101	Perray	Perray	NNP
cord-263862-zzys31e9	54	102	-	-	HYPH
cord-263862-zzys31e9	54	103	en	en	NNP
cord-263862-zzys31e9	54	104	-	-	HYPH
cord-263862-zzys31e9	54	105	Yvelines	Yvelines	NNP
cord-263862-zzys31e9	54	106	,	,	,
cord-263862-zzys31e9	54	107	France	France	NNP
cord-263862-zzys31e9	54	108	)	)	-RRB-
cord-263862-zzys31e9	54	109	,	,	,
cord-263862-zzys31e9	54	110	the	the	DT
cord-263862-zzys31e9	54	111	enzyme	enzyme	NN
cord-263862-zzys31e9	54	112	reaction	reaction	NN
cord-263862-zzys31e9	54	113	was	be	VBD
cord-263862-zzys31e9	54	114	stopped	stop	VBN
cord-263862-zzys31e9	54	115	with	with	IN
cord-263862-zzys31e9	54	116	the	the	DT
cord-263862-zzys31e9	54	117	addition	addition	NN
cord-263862-zzys31e9	54	118	of	of	IN
cord-263862-zzys31e9	54	119	phosphoric	phosphoric	JJ
cord-263862-zzys31e9	54	120	acid	acid	NN
cord-263862-zzys31e9	54	121	(	(	-LRB-
cord-263862-zzys31e9	54	122	1	1	CD
cord-263862-zzys31e9	54	123	M	M	NNP
cord-263862-zzys31e9	54	124	)	)	-RRB-
cord-263862-zzys31e9	54	125	,	,	,
cord-263862-zzys31e9	54	126	and	and	CC
cord-263862-zzys31e9	54	127	OD	OD	NNP
cord-263862-zzys31e9	54	128	values	value	NNS
cord-263862-zzys31e9	54	129	at	at	IN
cord-263862-zzys31e9	54	130	450	450	CD
cord-263862-zzys31e9	54	131	nm	nm	NNS
cord-263862-zzys31e9	54	132	were	be	VBD
cord-263862-zzys31e9	54	133	determined	determine	VBN
cord-263862-zzys31e9	54	134	.	.	.
cord-263862-zzys31e9	55	1	Antibody	antibody	NN
cord-263862-zzys31e9	55	2	titres	titre	NNS
cord-263862-zzys31e9	55	3	were	be	VBD
cord-263862-zzys31e9	55	4	calculated	calculate	VBN
cord-263862-zzys31e9	55	5	from	from	IN
cord-263862-zzys31e9	55	6	the	the	DT
cord-263862-zzys31e9	55	7	linear	linear	JJ
cord-263862-zzys31e9	55	8	regression	regression	NN
cord-263862-zzys31e9	55	9	curve	curve	NN
cord-263862-zzys31e9	55	10	of	of	IN
cord-263862-zzys31e9	55	11	a	a	DT
cord-263862-zzys31e9	55	12	standard	standard	JJ
cord-263862-zzys31e9	55	13	specific	specific	JJ
cord-263862-zzys31e9	55	14	serum	serum	NN
cord-263862-zzys31e9	55	15	originating	originate	VBG
cord-263862-zzys31e9	55	16	from	from	IN
cord-263862-zzys31e9	55	17	the	the	DT
cord-263862-zzys31e9	55	18	same	same	JJ
cord-263862-zzys31e9	55	19	animal	animal	NN
cord-263862-zzys31e9	55	20	species	specie	NNS
cord-263862-zzys31e9	55	21	as	as	IN
cord-263862-zzys31e9	55	22	the	the	DT
cord-263862-zzys31e9	55	23	samples	sample	NNS
cord-263862-zzys31e9	55	24	,	,	,
cord-263862-zzys31e9	55	25	present	present	JJ
cord-263862-zzys31e9	55	26	on	on	IN
cord-263862-zzys31e9	55	27	each	each	DT
cord-263862-zzys31e9	55	28	ELISA	ELISA	NNP
cord-263862-zzys31e9	55	29	plate	plate	NN
cord-263862-zzys31e9	55	30	(	(	-LRB-
cord-263862-zzys31e9	55	31	Softmax	Softmax	NNP
cord-263862-zzys31e9	55	32	software	software	NN
cord-263862-zzys31e9	55	33	TM	TM	NNP
cord-263862-zzys31e9	55	34	,	,	,
cord-263862-zzys31e9	55	35	Molecular	Molecular	NNP
cord-263862-zzys31e9	55	36	Devices	Devices	NNPS
cord-263862-zzys31e9	55	37	,	,	,
cord-263862-zzys31e9	55	38	Sunnyvale	Sunnyvale	NNP
cord-263862-zzys31e9	55	39	,	,	,
cord-263862-zzys31e9	55	40	CA	CA	NNP
cord-263862-zzys31e9	55	41	)	)	-RRB-
cord-263862-zzys31e9	55	42	.	.	.
cord-263862-zzys31e9	56	1	The	the	DT
cord-263862-zzys31e9	56	2	titre	titre	NN
cord-263862-zzys31e9	56	3	of	of	IN
cord-263862-zzys31e9	56	4	the	the	DT
cord-263862-zzys31e9	56	5	standard	standard	NN
cord-263862-zzys31e9	56	6	had	have	VBD
cord-263862-zzys31e9	56	7	been	be	VBN
cord-263862-zzys31e9	56	8	previously	previously	RB
cord-263862-zzys31e9	56	9	determined	determine	VBN
cord-263862-zzys31e9	56	10	in	in	IN
cord-263862-zzys31e9	56	11	15	15	CD
cord-263862-zzys31e9	56	12	independent	independent	JJ
cord-263862-zzys31e9	56	13	experiments	experiment	NNS
cord-263862-zzys31e9	56	14	.	.	.
cord-263862-zzys31e9	57	1	MultiScreen	MultiScreen	NNP
cord-263862-zzys31e9	57	2	HTS	HTS	NNP
cord-263862-zzys31e9	57	3	plates	plate	NNS
cord-263862-zzys31e9	57	4	(	(	-LRB-
cord-263862-zzys31e9	57	5	Millipore	Millipore	NNP
cord-263862-zzys31e9	57	6	,	,	,
cord-263862-zzys31e9	57	7	Bedford	Bedford	NNP
cord-263862-zzys31e9	57	8	,	,	,
cord-263862-zzys31e9	57	9	MA	MA	NNP
cord-263862-zzys31e9	57	10	)	)	-RRB-
cord-263862-zzys31e9	57	11	were	be	VBD
cord-263862-zzys31e9	57	12	coated	coat	VBN
cord-263862-zzys31e9	57	13	overnight	overnight	RB
cord-263862-zzys31e9	57	14	at	at	IN
cord-263862-zzys31e9	57	15	4	4	CD
cord-263862-zzys31e9	57	16	•	•	NN
cord-263862-zzys31e9	58	1	C	C	NNP
cord-263862-zzys31e9	58	2	with	with	IN
cord-263862-zzys31e9	58	3	anti	anti	JJ
cord-263862-zzys31e9	58	4	-	-	JJ
cord-263862-zzys31e9	58	5	IFN-	ifn-	JJ
cord-263862-zzys31e9	58	6	␥	␥	CD
cord-263862-zzys31e9	58	7	capture	capture	NN
cord-263862-zzys31e9	58	8	monoclonal	monoclonal	JJ
cord-263862-zzys31e9	58	9	antibody	antibody	NN
cord-263862-zzys31e9	58	10	(	(	-LRB-
cord-263862-zzys31e9	58	11	mAb	mab	NN
cord-263862-zzys31e9	58	12	)	)	-RRB-
cord-263862-zzys31e9	59	1	(	(	-LRB-
cord-263862-zzys31e9	59	2	Clone	clone	VB
cord-263862-zzys31e9	59	3	No	no	NN
cord-263862-zzys31e9	59	4	.	.	.
cord-263862-zzys31e9	59	5	R4	R4	NNP
cord-263862-zzys31e9	59	6	-	-	HYPH
cord-263862-zzys31e9	59	7	6A2	6a2	CD
cord-263862-zzys31e9	59	8	,	,	,
cord-263862-zzys31e9	59	9	BD	BD	NNP
cord-263862-zzys31e9	59	10	Pharmingen	Pharmingen	NNP
cord-263862-zzys31e9	59	11	,	,	,
cord-263862-zzys31e9	59	12	San	San	NNP
cord-263862-zzys31e9	59	13	Diego	Diego	NNP
cord-263862-zzys31e9	59	14	,	,	,
cord-263862-zzys31e9	59	15	CA	CA	NNP
cord-263862-zzys31e9	59	16	)	)	-RRB-
cord-263862-zzys31e9	59	17	,	,	,
cord-263862-zzys31e9	59	18	washed	wash	VBD
cord-263862-zzys31e9	59	19	and	and	CC
cord-263862-zzys31e9	59	20	blocked	block	VBN
cord-263862-zzys31e9	59	21	.	.	.
cord-263862-zzys31e9	60	1	Responder	responder	NN
cord-263862-zzys31e9	60	2	spleen	spleen	NN
cord-263862-zzys31e9	60	3	cells	cell	NNS
cord-263862-zzys31e9	60	4	were	be	VBD
cord-263862-zzys31e9	60	5	added	add	VBN
cord-263862-zzys31e9	60	6	at	at	IN
cord-263862-zzys31e9	60	7	a	a	DT
cord-263862-zzys31e9	60	8	concentration	concentration	NN
cord-263862-zzys31e9	60	9	of	of	IN
cord-263862-zzys31e9	60	10	2	2	CD
cord-263862-zzys31e9	60	11	×	×	CD
cord-263862-zzys31e9	60	12	10	10	CD
cord-263862-zzys31e9	60	13	5	5	CD
cord-263862-zzys31e9	60	14	cells	cell	NNS
cord-263862-zzys31e9	60	15	/	/	SYM
cord-263862-zzys31e9	60	16	well	well	RB
cord-263862-zzys31e9	60	17	in	in	IN
cord-263862-zzys31e9	60	18	RPMI	RPMI	NNP
cord-263862-zzys31e9	60	19	1640	1640	CD
cord-263862-zzys31e9	61	1	(	(	-LRB-
cord-263862-zzys31e9	61	2	Gibco	Gibco	NNP
cord-263862-zzys31e9	61	3	)	)	-RRB-
cord-263862-zzys31e9	61	4	supplemented	supplement	VBD
cord-263862-zzys31e9	61	5	with	with	IN
cord-263862-zzys31e9	61	6	10	10	CD
cord-263862-zzys31e9	61	7	%	%	NN
cord-263862-zzys31e9	61	8	FCS	FCS	NNP
cord-263862-zzys31e9	61	9	(	(	-LRB-
cord-263862-zzys31e9	61	10	Hyclone	Hyclone	NNP
cord-263862-zzys31e9	61	11	,	,	,
cord-263862-zzys31e9	61	12	Logan	Logan	NNP
cord-263862-zzys31e9	61	13	,	,	,
cord-263862-zzys31e9	61	14	UT	UT	NNP
cord-263862-zzys31e9	61	15	)	)	-RRB-
cord-263862-zzys31e9	61	16	,	,	,
cord-263862-zzys31e9	61	17	Penicillin	Penicillin	NNP
cord-263862-zzys31e9	61	18	-	-	HYPH
cord-263862-zzys31e9	61	19	Streptomycin	Streptomycin	NNP
cord-263862-zzys31e9	61	20	(	(	-LRB-
cord-263862-zzys31e9	61	21	Gibco	Gibco	NNP
cord-263862-zzys31e9	61	22	)	)	-RRB-
cord-263862-zzys31e9	61	23	,	,	,
cord-263862-zzys31e9	61	24	200	200	CD
cord-263862-zzys31e9	61	25	mM	mm	CD
cord-263862-zzys31e9	61	26	lglutamine	lglutamine	NN
cord-263862-zzys31e9	61	27	(	(	-LRB-
cord-263862-zzys31e9	61	28	Gibco	Gibco	NNP
cord-263862-zzys31e9	61	29	)	)	-RRB-
cord-263862-zzys31e9	61	30	,	,	,
cord-263862-zzys31e9	61	31	and	and	CC
cord-263862-zzys31e9	61	32	50	50	CD
cord-263862-zzys31e9	61	33	mM	mm	NN
cord-263862-zzys31e9	61	34	␤	␤	XX
cord-263862-zzys31e9	62	1	-mercaptoethanol	-mercaptoethanol	:
cord-263862-zzys31e9	62	2	(	(	-LRB-
cord-263862-zzys31e9	62	3	Gibco	Gibco	NNP
cord-263862-zzys31e9	62	4	)	)	-RRB-
cord-263862-zzys31e9	62	5	.	.	.
cord-263862-zzys31e9	63	1	Cells	cell	NNS
cord-263862-zzys31e9	63	2	were	be	VBD
cord-263862-zzys31e9	63	3	stimulated	stimulate	VBN
cord-263862-zzys31e9	63	4	in	in	IN
cord-263862-zzys31e9	63	5	triplicate	triplicate	NN
cord-263862-zzys31e9	63	6	with	with	IN
cord-263862-zzys31e9	63	7	1	1	CD
cord-263862-zzys31e9	63	8	g	g	NN
cord-263862-zzys31e9	63	9	/	/	SYM
cord-263862-zzys31e9	63	10	ml	ml	NN
cord-263862-zzys31e9	63	11	of	of	IN
cord-263862-zzys31e9	63	12	9	9	CD
cord-263862-zzys31e9	63	13	or	or	CC
cord-263862-zzys31e9	63	14	15	15	CD
cord-263862-zzys31e9	63	15	mer	mer	NNP
cord-263862-zzys31e9	63	16	Tat	Tat	NNP
cord-263862-zzys31e9	63	17	or	or	CC
cord-263862-zzys31e9	63	18	gag	gag	NN
cord-263862-zzys31e9	63	19	peptides	peptide	NNS
cord-263862-zzys31e9	64	1	(	(	-LRB-
cord-263862-zzys31e9	64	2	Neosystem	Neosystem	NNP
cord-263862-zzys31e9	64	3	,	,	,
cord-263862-zzys31e9	64	4	Strasbourg	Strasbourg	NNP
cord-263862-zzys31e9	64	5	,	,	,
cord-263862-zzys31e9	64	6	France	France	NNP
cord-263862-zzys31e9	64	7	)	)	-RRB-
cord-263862-zzys31e9	64	8	,	,	,
cord-263862-zzys31e9	64	9	medium	medium	NN
cord-263862-zzys31e9	64	10	alone	alone	RB
cord-263862-zzys31e9	64	11	as	as	IN
cord-263862-zzys31e9	64	12	negative	negative	JJ
cord-263862-zzys31e9	64	13	control	control	NN
cord-263862-zzys31e9	64	14	and	and	CC
cord-263862-zzys31e9	64	15	PMA	PMA	NNP
cord-263862-zzys31e9	64	16	(	(	-LRB-
cord-263862-zzys31e9	64	17	Sigma	Sigma	NNP
cord-263862-zzys31e9	64	18	-	-	HYPH
cord-263862-zzys31e9	64	19	Aldrich	Aldrich	NNP
cord-263862-zzys31e9	64	20	,	,	,
cord-263862-zzys31e9	64	21	St.	St.	NNP
cord-263862-zzys31e9	64	22	Louis	Louis	NNP
cord-263862-zzys31e9	64	23	,	,	,
cord-263862-zzys31e9	64	24	MO)/anti	MO)/anti	NNP
cord-263862-zzys31e9	64	25	-	-	HYPH
cord-263862-zzys31e9	64	26	CD3	CD3	NNP
cord-263862-zzys31e9	64	27	(	(	-LRB-
cord-263862-zzys31e9	64	28	BD	BD	NNP
cord-263862-zzys31e9	64	29	Pharmingen	Pharmingen	NNP
cord-263862-zzys31e9	64	30	)	)	-RRB-
cord-263862-zzys31e9	64	31	as	as	IN
cord-263862-zzys31e9	64	32	positive	positive	JJ
cord-263862-zzys31e9	64	33	control	control	NN
cord-263862-zzys31e9	64	34	.	.	.
cord-263862-zzys31e9	65	1	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	65	2	specific	specific	JJ
cord-263862-zzys31e9	65	3	immune	immune	JJ
cord-263862-zzys31e9	65	4	responses	response	NNS
cord-263862-zzys31e9	65	5	were	be	VBD
cord-263862-zzys31e9	65	6	measured	measure	VBN
cord-263862-zzys31e9	65	7	by	by	IN
cord-263862-zzys31e9	65	8	adding	add	VBG
cord-263862-zzys31e9	65	9	P815	p815	NN
cord-263862-zzys31e9	65	10	cells	cell	NNS
cord-263862-zzys31e9	65	11	(	(	-LRB-
cord-263862-zzys31e9	65	12	Mouse	Mouse	NNP
cord-263862-zzys31e9	65	13	lymphoblast	lymphoblast	NN
cord-263862-zzys31e9	65	14	-	-	HYPH
cord-263862-zzys31e9	65	15	like	like	JJ
cord-263862-zzys31e9	65	16	mastocytoma	mastocytoma	NNP
cord-263862-zzys31e9	65	17	cell	cell	NN
cord-263862-zzys31e9	65	18	line	line	NN
cord-263862-zzys31e9	65	19	)	)	-RRB-
cord-263862-zzys31e9	65	20	that	that	WDT
cord-263862-zzys31e9	65	21	had	have	VBD
cord-263862-zzys31e9	65	22	been	be	VBN
cord-263862-zzys31e9	65	23	infected	infect	VBN
cord-263862-zzys31e9	65	24	with	with	IN
cord-263862-zzys31e9	65	25	a	a	DT
cord-263862-zzys31e9	65	26	multiplicity	multiplicity	NN
cord-263862-zzys31e9	65	27	of	of	IN
cord-263862-zzys31e9	65	28	infection	infection	NN
cord-263862-zzys31e9	65	29	(	(	-LRB-
cord-263862-zzys31e9	65	30	MOI	MOI	NNP
cord-263862-zzys31e9	65	31	)	)	-RRB-
cord-263862-zzys31e9	65	32	of	of	IN
cord-263862-zzys31e9	65	33	20	20	CD
cord-263862-zzys31e9	65	34	of	of	IN
cord-263862-zzys31e9	65	35	parental	parental	JJ
cord-263862-zzys31e9	65	36	virus	virus	NN
cord-263862-zzys31e9	65	37	(	(	-LRB-
cord-263862-zzys31e9	65	38	CpPP	CpPP	NNP
cord-263862-zzys31e9	65	39	)	)	-RRB-
cord-263862-zzys31e9	65	40	overnight	overnight	RB
cord-263862-zzys31e9	65	41	.	.	.
cord-263862-zzys31e9	66	1	Cultures	culture	NNS
cord-263862-zzys31e9	66	2	were	be	VBD
cord-263862-zzys31e9	66	3	incubated	incubate	VBN
cord-263862-zzys31e9	66	4	overnight	overnight	RB
cord-263862-zzys31e9	66	5	at	at	IN
cord-263862-zzys31e9	66	6	37	37	CD
cord-263862-zzys31e9	67	1	•	•	NNP
cord-263862-zzys31e9	68	1	C/5	C/5	NNP
cord-263862-zzys31e9	68	2	%	%	NN
cord-263862-zzys31e9	68	3	CO	CO	NNP
cord-263862-zzys31e9	68	4	2	2	CD
cord-263862-zzys31e9	68	5	.	.	.
cord-263862-zzys31e9	69	1	The	the	DT
cord-263862-zzys31e9	69	2	following	following	JJ
cord-263862-zzys31e9	69	3	day	day	NN
cord-263862-zzys31e9	69	4	,	,	,
cord-263862-zzys31e9	69	5	detection	detection	NN
cord-263862-zzys31e9	69	6	using	use	VBG
cord-263862-zzys31e9	69	7	mAb	mab	NN
cord-263862-zzys31e9	69	8	IFN-	IFN-	NNP
cord-263862-zzys31e9	69	9	␥	␥	XX
cord-263862-zzys31e9	69	10	-biotin	-biotin	NFP
cord-263862-zzys31e9	69	11	(	(	-LRB-
cord-263862-zzys31e9	69	12	clone	clone	VB
cord-263862-zzys31e9	69	13	No	no	NN
cord-263862-zzys31e9	69	14	.	.	.
cord-263862-zzys31e9	69	15	XMG1.2	XMG1.2	NNP
cord-263862-zzys31e9	69	16	,	,	,
cord-263862-zzys31e9	69	17	BD	BD	NNP
cord-263862-zzys31e9	69	18	Pharmingen	Pharmingen	NNP
cord-263862-zzys31e9	69	19	)	)	-RRB-
cord-263862-zzys31e9	69	20	,	,	,
cord-263862-zzys31e9	69	21	followed	follow	VBN
cord-263862-zzys31e9	69	22	by	by	IN
cord-263862-zzys31e9	69	23	Streptavidin	Streptavidin	NNP
cord-263862-zzys31e9	69	24	-	-	HYPH
cord-263862-zzys31e9	69	25	HRP	HRP	NNP
cord-263862-zzys31e9	69	26	(	(	-LRB-
cord-263862-zzys31e9	69	27	Southern	Southern	NNP
cord-263862-zzys31e9	69	28	Biotech	Biotech	NNP
cord-263862-zzys31e9	69	29	,	,	,
cord-263862-zzys31e9	69	30	Birmingham	Birmingham	NNP
cord-263862-zzys31e9	69	31	,	,	,
cord-263862-zzys31e9	69	32	AL	AL	NNP
cord-263862-zzys31e9	69	33	)	)	-RRB-
cord-263862-zzys31e9	69	34	was	be	VBD
cord-263862-zzys31e9	69	35	visualized	visualize	VBN
cord-263862-zzys31e9	69	36	using	use	VBG
cord-263862-zzys31e9	69	37	3-amino-9-ethylcarbazole	3-amino-9-ethylcarbazole	CD
cord-263862-zzys31e9	69	38	(	(	-LRB-
cord-263862-zzys31e9	69	39	AEC	AEC	NNP
cord-263862-zzys31e9	69	40	)	)	-RRB-
cord-263862-zzys31e9	69	41	substrate	substrate	NN
cord-263862-zzys31e9	69	42	(	(	-LRB-
cord-263862-zzys31e9	69	43	Sigma	Sigma	NNP
cord-263862-zzys31e9	69	44	-	-	HYPH
cord-263862-zzys31e9	69	45	Aldrich	Aldrich	NNP
cord-263862-zzys31e9	69	46	)	)	-RRB-
cord-263862-zzys31e9	69	47	.	.	.
cord-263862-zzys31e9	70	1	IFN-	IFN-	NNP
cord-263862-zzys31e9	70	2	␥	␥	NNP
cord-263862-zzys31e9	70	3	producing	produce	VBG
cord-263862-zzys31e9	70	4	spots	spot	NNS
cord-263862-zzys31e9	70	5	were	be	VBD
cord-263862-zzys31e9	70	6	counted	count	VBN
cord-263862-zzys31e9	70	7	using	use	VBG
cord-263862-zzys31e9	70	8	an	an	DT
cord-263862-zzys31e9	70	9	automated	automate	VBN
cord-263862-zzys31e9	70	10	ELISPOT	ELISPOT	NNP
cord-263862-zzys31e9	70	11	reader	reader	NN
cord-263862-zzys31e9	70	12	equipped	equip	VBN
cord-263862-zzys31e9	70	13	with	with	IN
cord-263862-zzys31e9	70	14	Spot	Spot	NNP
cord-263862-zzys31e9	70	15	TM	TM	NNP
cord-263862-zzys31e9	70	16	software	software	NN
cord-263862-zzys31e9	70	17	(	(	-LRB-
cord-263862-zzys31e9	70	18	MicroVision	MicroVision	NNP
cord-263862-zzys31e9	70	19	Instruments	Instruments	NNPS
cord-263862-zzys31e9	70	20	,	,	,
cord-263862-zzys31e9	70	21	Evry	Evry	NNP
cord-263862-zzys31e9	70	22	,	,	,
cord-263862-zzys31e9	70	23	France	France	NNP
cord-263862-zzys31e9	70	24	)	)	-RRB-
cord-263862-zzys31e9	70	25	.	.	.
cord-263862-zzys31e9	71	1	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	71	2	's	's	POS
cord-263862-zzys31e9	71	3	ability	ability	NN
cord-263862-zzys31e9	71	4	to	to	TO
cord-263862-zzys31e9	71	5	induce	induce	VB
cord-263862-zzys31e9	71	6	early	early	RB
cord-263862-zzys31e9	71	7	circulating	circulate	VBG
cord-263862-zzys31e9	72	1	IFN-	IFN-	NNP
cord-263862-zzys31e9	72	2	␥	␥	NFP
cord-263862-zzys31e9	72	3	following	follow	VBG
cord-263862-zzys31e9	73	1	i.m	i.m	NNP
cord-263862-zzys31e9	73	2	.	.	NNP
cord-263862-zzys31e9	73	3	injection	injection	NN
cord-263862-zzys31e9	73	4	was	be	VBD
cord-263862-zzys31e9	73	5	evaluated	evaluate	VBN
cord-263862-zzys31e9	73	6	using	use	VBG
cord-263862-zzys31e9	73	7	an	an	DT
cord-263862-zzys31e9	73	8	in	in	IN
cord-263862-zzys31e9	73	9	vivo	vivo	NN
cord-263862-zzys31e9	73	10	IFN-	IFN-	NNP
cord-263862-zzys31e9	73	11	␥	␥	CD
cord-263862-zzys31e9	73	12	detection	detection	NN
cord-263862-zzys31e9	73	13	assay	assay	NN
cord-263862-zzys31e9	73	14	as	as	IN
cord-263862-zzys31e9	73	15	described	describe	VBN
cord-263862-zzys31e9	73	16	by	by	IN
cord-263862-zzys31e9	73	17	the	the	DT
cord-263862-zzys31e9	73	18	manufacturer	manufacturer	NN
cord-263862-zzys31e9	73	19	(	(	-LRB-
cord-263862-zzys31e9	73	20	BD	BD	NNP
cord-263862-zzys31e9	73	21	Pharmingen	Pharmingen	NNP
cord-263862-zzys31e9	73	22	)	)	-RRB-
cord-263862-zzys31e9	73	23	.	.	.
cord-263862-zzys31e9	74	1	Briefly	briefly	RB
cord-263862-zzys31e9	74	2	,	,	,
cord-263862-zzys31e9	74	3	prior	prior	RB
cord-263862-zzys31e9	74	4	to	to	IN
cord-263862-zzys31e9	74	5	i.m	i.m	NNP
cord-263862-zzys31e9	74	6	.	.	NNP
cord-263862-zzys31e9	74	7	injection	injection	NN
cord-263862-zzys31e9	74	8	with	with	IN
cord-263862-zzys31e9	74	9	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	74	10	or	or	CC
cord-263862-zzys31e9	74	11	Placebo	Placebo	NNP
cord-263862-zzys31e9	74	12	groups	group	NNS
cord-263862-zzys31e9	74	13	of	of	IN
cord-263862-zzys31e9	74	14	Balb	Balb	NNP
cord-263862-zzys31e9	74	15	/	/	SYM
cord-263862-zzys31e9	74	16	c	c	NN
cord-263862-zzys31e9	74	17	mice	mouse	NNS
cord-263862-zzys31e9	74	18	were	be	VBD
cord-263862-zzys31e9	74	19	given	give	VBN
cord-263862-zzys31e9	74	20	an	an	DT
cord-263862-zzys31e9	74	21	intraperitoneal	intraperitoneal	NN
cord-263862-zzys31e9	74	22	(	(	-LRB-
cord-263862-zzys31e9	74	23	i.p	i.p	NNP
cord-263862-zzys31e9	74	24	.	.	.
cord-263862-zzys31e9	74	25	)	)	-RRB-
cord-263862-zzys31e9	74	26	injection	injection	NN
cord-263862-zzys31e9	74	27	with	with	IN
cord-263862-zzys31e9	74	28	10	10	CD
cord-263862-zzys31e9	74	29	g	g	NN
cord-263862-zzys31e9	74	30	/	/	SYM
cord-263862-zzys31e9	74	31	dose	dose	NN
cord-263862-zzys31e9	74	32	of	of	IN
cord-263862-zzys31e9	74	33	a	a	DT
cord-263862-zzys31e9	74	34	biotin	biotin	NN
cord-263862-zzys31e9	74	35	-	-	HYPH
cord-263862-zzys31e9	74	36	IFN-	IFN-	NNP
cord-263862-zzys31e9	74	37	␥	␥	NNP
cord-263862-zzys31e9	74	38	mAb	mab	NN
cord-263862-zzys31e9	74	39	,	,	,
cord-263862-zzys31e9	74	40	serum	serum	NN
cord-263862-zzys31e9	74	41	samples	sample	NNS
cord-263862-zzys31e9	74	42	were	be	VBD
cord-263862-zzys31e9	74	43	removed	remove	VBN
cord-263862-zzys31e9	74	44	at	at	IN
cord-263862-zzys31e9	74	45	various	various	JJ
cord-263862-zzys31e9	74	46	time	time	NN
cord-263862-zzys31e9	74	47	-	-	HYPH
cord-263862-zzys31e9	74	48	points	point	NNS
cord-263862-zzys31e9	74	49	and	and	CC
cord-263862-zzys31e9	74	50	frozen	freeze	VBN
cord-263862-zzys31e9	74	51	at	at	IN
cord-263862-zzys31e9	74	52	−20	−20	NNP
cord-263862-zzys31e9	74	53	•	•	NNP
cord-263862-zzys31e9	74	54	C	C	NNP
cord-263862-zzys31e9	74	55	until	until	IN
cord-263862-zzys31e9	74	56	analysis	analysis	NN
cord-263862-zzys31e9	74	57	of	of	IN
cord-263862-zzys31e9	74	58	the	the	DT
cord-263862-zzys31e9	74	59	IFN-	IFN-	NNP
cord-263862-zzys31e9	74	60	␥	␥	NNP
cord-263862-zzys31e9	74	61	mAb	mab	NN
cord-263862-zzys31e9	74	62	complex	complex	NN
cord-263862-zzys31e9	74	63	by	by	IN
cord-263862-zzys31e9	74	64	ELISA	ELISA	NNP
cord-263862-zzys31e9	74	65	.	.	.
cord-263862-zzys31e9	75	1	In	in	IN
cord-263862-zzys31e9	75	2	some	some	DT
cord-263862-zzys31e9	75	3	experiments	experiment	NNS
cord-263862-zzys31e9	75	4	,	,	,
cord-263862-zzys31e9	75	5	NK	NK	NNP
cord-263862-zzys31e9	75	6	cells	cell	NNS
cord-263862-zzys31e9	75	7	were	be	VBD
cord-263862-zzys31e9	75	8	depleted	deplete	VBN
cord-263862-zzys31e9	75	9	using	use	VBG
cord-263862-zzys31e9	75	10	antiasialo	antiasialo	NNP
cord-263862-zzys31e9	75	11	GM1	GM1	NNP
cord-263862-zzys31e9	75	12	polyclonal	polyclonal	JJ
cord-263862-zzys31e9	75	13	antibody	antibody	NN
cord-263862-zzys31e9	75	14	(	(	-LRB-
cord-263862-zzys31e9	75	15	Cedarlane	Cedarlane	NNP
cord-263862-zzys31e9	75	16	Laboratories	Laboratories	NNPS
cord-263862-zzys31e9	75	17	,	,	,
cord-263862-zzys31e9	75	18	Ontario	Ontario	NNP
cord-263862-zzys31e9	75	19	,	,	,
cord-263862-zzys31e9	75	20	Canada	Canada	NNP
cord-263862-zzys31e9	75	21	)	)	-RRB-
cord-263862-zzys31e9	75	22	i.p	i.p	NNP
cord-263862-zzys31e9	75	23	.	.	NNP
cord-263862-zzys31e9	75	24	at	at	IN
cord-263862-zzys31e9	75	25	day	day	NN
cord-263862-zzys31e9	75	26	−5	−5	NNP
cord-263862-zzys31e9	75	27	and	and	CC
cord-263862-zzys31e9	75	28	day	day	NN
cord-263862-zzys31e9	75	29	0	0	CD
cord-263862-zzys31e9	75	30	at	at	IN
cord-263862-zzys31e9	75	31	30	30	CD
cord-263862-zzys31e9	75	32	g	g	NN
cord-263862-zzys31e9	75	33	/	/	SYM
cord-263862-zzys31e9	75	34	dose	dose	NN
cord-263862-zzys31e9	75	35	.	.	.
cord-263862-zzys31e9	76	1	Control	control	NN
cord-263862-zzys31e9	76	2	mice	mouse	NNS
cord-263862-zzys31e9	76	3	received	receive	VBD
cord-263862-zzys31e9	76	4	the	the	DT
cord-263862-zzys31e9	76	5	same	same	JJ
cord-263862-zzys31e9	76	6	dose	dose	NN
cord-263862-zzys31e9	76	7	of	of	IN
cord-263862-zzys31e9	76	8	non	non	JJ
cord-263862-zzys31e9	76	9	-	-	JJ
cord-263862-zzys31e9	76	10	specific	specific	JJ
cord-263862-zzys31e9	76	11	rabbit	rabbit	NN
cord-263862-zzys31e9	76	12	IgG	igg	NN
cord-263862-zzys31e9	76	13	(	(	-LRB-
cord-263862-zzys31e9	76	14	Caltag	Caltag	NNP
cord-263862-zzys31e9	76	15	Laboratories	Laboratories	NNPS
cord-263862-zzys31e9	76	16	,	,	,
cord-263862-zzys31e9	76	17	Burlingame	Burlingame	NNP
cord-263862-zzys31e9	76	18	,	,	,
cord-263862-zzys31e9	76	19	CA	CA	NNP
cord-263862-zzys31e9	76	20	)	)	-RRB-
cord-263862-zzys31e9	76	21	.	.	.
cord-263862-zzys31e9	77	1	The	the	DT
cord-263862-zzys31e9	77	2	capture	capture	NN
cord-263862-zzys31e9	78	1	IFN-	IFN-	NNP
cord-263862-zzys31e9	78	2	␥	␥	NNP
cord-263862-zzys31e9	78	3	mAb	mab	NN
cord-263862-zzys31e9	78	4	with	with	IN
cord-263862-zzys31e9	78	5	either	either	CC
cord-263862-zzys31e9	78	6	Placebo	Placebo	NNP
cord-263862-zzys31e9	78	7	or	or	CC
cord-263862-zzys31e9	78	8	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	78	9	were	be	VBD
cord-263862-zzys31e9	78	10	injected	inject	VBN
cord-263862-zzys31e9	78	11	as	as	IN
cord-263862-zzys31e9	78	12	described	describe	VBN
cord-263862-zzys31e9	78	13	and	and	CC
cord-263862-zzys31e9	78	14	serum	serum	NN
cord-263862-zzys31e9	78	15	samples	sample	NNS
cord-263862-zzys31e9	78	16	were	be	VBD
cord-263862-zzys31e9	78	17	collected	collect	VBN
cord-263862-zzys31e9	78	18	at	at	IN
cord-263862-zzys31e9	78	19	72	72	CD
cord-263862-zzys31e9	78	20	h	h	NN
cord-263862-zzys31e9	78	21	postimmunisation	postimmunisation	NN
cord-263862-zzys31e9	78	22	,	,	,
cord-263862-zzys31e9	78	23	and	and	CC
cord-263862-zzys31e9	78	24	frozen	freeze	VBN
cord-263862-zzys31e9	78	25	at	at	IN
cord-263862-zzys31e9	78	26	−20	−20	NNP
cord-263862-zzys31e9	78	27	•	•	NNP
cord-263862-zzys31e9	78	28	C	C	NNP
cord-263862-zzys31e9	78	29	until	until	IN
cord-263862-zzys31e9	78	30	analysis	analysis	NN
cord-263862-zzys31e9	78	31	by	by	IN
cord-263862-zzys31e9	78	32	ELISA	ELISA	NNP
cord-263862-zzys31e9	78	33	.	.	.
cord-263862-zzys31e9	79	1	Spleens	spleen	NNS
cord-263862-zzys31e9	79	2	were	be	VBD
cord-263862-zzys31e9	79	3	removed	remove	VBN
cord-263862-zzys31e9	79	4	from	from	IN
cord-263862-zzys31e9	79	5	both	both	DT
cord-263862-zzys31e9	79	6	control	control	NN
cord-263862-zzys31e9	79	7	and	and	CC
cord-263862-zzys31e9	79	8	treated	treat	VBN
cord-263862-zzys31e9	79	9	animals	animal	NNS
cord-263862-zzys31e9	79	10	and	and	CC
cord-263862-zzys31e9	79	11	the	the	DT
cord-263862-zzys31e9	79	12	efficacy	efficacy	NN
cord-263862-zzys31e9	79	13	of	of	IN
cord-263862-zzys31e9	79	14	the	the	DT
cord-263862-zzys31e9	79	15	NK	NK	NNP
cord-263862-zzys31e9	79	16	cell	cell	NN
cord-263862-zzys31e9	79	17	depletion	depletion	NN
cord-263862-zzys31e9	79	18	measured	measure	VBN
cord-263862-zzys31e9	79	19	by	by	IN
cord-263862-zzys31e9	79	20	evaluating	evaluate	VBG
cord-263862-zzys31e9	79	21	the	the	DT
cord-263862-zzys31e9	79	22	%	%	NN
cord-263862-zzys31e9	79	23	of	of	IN
cord-263862-zzys31e9	79	24	spleen	spleen	NN
cord-263862-zzys31e9	79	25	cells	cell	NNS
cord-263862-zzys31e9	79	26	expressing	express	VBG
cord-263862-zzys31e9	79	27	the	the	DT
cord-263862-zzys31e9	79	28	NK	NK	NNP
cord-263862-zzys31e9	79	29	cell	cell	NN
cord-263862-zzys31e9	79	30	marker	marker	NN
cord-263862-zzys31e9	79	31	CD49b	CD49b	NNP
cord-263862-zzys31e9	79	32	by	by	IN
cord-263862-zzys31e9	79	33	flow	flow	NN
cord-263862-zzys31e9	79	34	cytometry	cytometry	NN
cord-263862-zzys31e9	79	35	using	use	VBG
cord-263862-zzys31e9	79	36	a	a	DT
cord-263862-zzys31e9	79	37	specific	specific	JJ
cord-263862-zzys31e9	79	38	mAb	mab	NN
cord-263862-zzys31e9	79	39	,	,	,
cord-263862-zzys31e9	79	40	clone	clone	VB
cord-263862-zzys31e9	79	41	no	no	UH
cord-263862-zzys31e9	79	42	.	.	.
cord-263862-zzys31e9	80	1	DX5	DX5	NNP
cord-263862-zzys31e9	80	2	(	(	-LRB-
cord-263862-zzys31e9	80	3	BD	BD	NNP
cord-263862-zzys31e9	80	4	Pharmingen	Pharmingen	NNP
cord-263862-zzys31e9	80	5	)	)	-RRB-
cord-263862-zzys31e9	80	6	.	.	.
cord-263862-zzys31e9	81	1	Secretion	secretion	NN
cord-263862-zzys31e9	81	2	of	of	IN
cord-263862-zzys31e9	81	3	cytokines	cytokine	NNS
cord-263862-zzys31e9	81	4	/	/	SYM
cord-263862-zzys31e9	81	5	chemokines	chemokine	NNS
cord-263862-zzys31e9	81	6	was	be	VBD
cord-263862-zzys31e9	81	7	analyzed	analyze	VBN
cord-263862-zzys31e9	81	8	by	by	IN
cord-263862-zzys31e9	81	9	ELISA	ELISA	NNP
cord-263862-zzys31e9	81	10	using	use	VBG
cord-263862-zzys31e9	81	11	commercially	commercially	RB
cord-263862-zzys31e9	81	12	available	available	JJ
cord-263862-zzys31e9	81	13	matched	match	VBN
cord-263862-zzys31e9	81	14	pairs	pair	NNS
cord-263862-zzys31e9	81	15	of	of	IN
cord-263862-zzys31e9	81	16	mAbs	mAbs	NNP
cord-263862-zzys31e9	81	17	;	;	:
cord-263862-zzys31e9	81	18	murine	murine	JJ
cord-263862-zzys31e9	81	19	CXCL10	CXCL10	NNP
cord-263862-zzys31e9	81	20	and	and	CC
cord-263862-zzys31e9	81	21	CXCL16	CXCL16	NNP
cord-263862-zzys31e9	82	1	(	(	-LRB-
cord-263862-zzys31e9	82	2	R&D	R&D	NNP
cord-263862-zzys31e9	82	3	Systems	Systems	NNP
cord-263862-zzys31e9	82	4	,	,	,
cord-263862-zzys31e9	82	5	Minneapolis	Minneapolis	NNP
cord-263862-zzys31e9	82	6	,	,	,
cord-263862-zzys31e9	82	7	MN	MN	NNP
cord-263862-zzys31e9	82	8	)	)	-RRB-
cord-263862-zzys31e9	82	9	;	;	,
cord-263862-zzys31e9	82	10	murine	murine	JJ
cord-263862-zzys31e9	82	11	IL-10	IL-10	NNP
cord-263862-zzys31e9	82	12	,	,	,
cord-263862-zzys31e9	83	1	TNF-	TNF-	NNP
cord-263862-zzys31e9	83	2	␣	␣	XX
cord-263862-zzys31e9	83	3	,	,	,
cord-263862-zzys31e9	83	4	IL-5	IL-5	NNP
cord-263862-zzys31e9	83	5	,	,	,
cord-263862-zzys31e9	83	6	IFN-	IFN-	NNP
cord-263862-zzys31e9	83	7	␥	␥	NNP
cord-263862-zzys31e9	83	8	,	,	,
cord-263862-zzys31e9	83	9	IL-12p40	IL-12p40	NNP
cord-263862-zzys31e9	83	10	,	,	,
cord-263862-zzys31e9	83	11	IL-6	IL-6	NNP
cord-263862-zzys31e9	83	12	,	,	,
cord-263862-zzys31e9	83	13	and	and	CC
cord-263862-zzys31e9	83	14	human	human	JJ
cord-263862-zzys31e9	84	1	IL-10	IL-10	NNP
cord-263862-zzys31e9	84	2	and	and	CC
cord-263862-zzys31e9	84	3	IL-12p70	IL-12p70	NNP
cord-263862-zzys31e9	84	4	(	(	-LRB-
cord-263862-zzys31e9	84	5	BD	BD	NNP
cord-263862-zzys31e9	84	6	PharMingen	PharMingen	NNP
cord-263862-zzys31e9	84	7	,	,	,
cord-263862-zzys31e9	84	8	San	San	NNP
cord-263862-zzys31e9	84	9	Diego	Diego	NNP
cord-263862-zzys31e9	84	10	,	,	,
cord-263862-zzys31e9	84	11	CA	CA	NNP
cord-263862-zzys31e9	84	12	)	)	-RRB-
cord-263862-zzys31e9	84	13	.	.	.
cord-263862-zzys31e9	85	1	The	the	DT
cord-263862-zzys31e9	85	2	limit	limit	NN
cord-263862-zzys31e9	85	3	of	of	IN
cord-263862-zzys31e9	85	4	sensitivity	sensitivity	NN
cord-263862-zzys31e9	85	5	for	for	IN
cord-263862-zzys31e9	85	6	detection	detection	NN
cord-263862-zzys31e9	85	7	was	be	VBD
cord-263862-zzys31e9	85	8	15	15	CD
cord-263862-zzys31e9	85	9	pg	pg	NN
cord-263862-zzys31e9	85	10	/	/	SYM
cord-263862-zzys31e9	85	11	ml	ml	NN
cord-263862-zzys31e9	85	12	for	for	IN
cord-263862-zzys31e9	85	13	all	all	DT
cord-263862-zzys31e9	85	14	ELISA	ELISA	NNP
cord-263862-zzys31e9	85	15	assays	assay	NNS
cord-263862-zzys31e9	85	16	.	.	.
cord-263862-zzys31e9	86	1	Murine	murine	JJ
cord-263862-zzys31e9	86	2	IFN-	IFN-	NNP
cord-263862-zzys31e9	87	1	␣	␣	NNP
cord-263862-zzys31e9	87	2	was	be	VBD
cord-263862-zzys31e9	87	3	detected	detect	VBN
cord-263862-zzys31e9	87	4	in	in	IN
cord-263862-zzys31e9	87	5	serum	serum	NN
cord-263862-zzys31e9	87	6	samples	sample	NNS
cord-263862-zzys31e9	87	7	using	use	VBG
cord-263862-zzys31e9	87	8	a	a	DT
cord-263862-zzys31e9	87	9	commercially	commercially	RB
cord-263862-zzys31e9	87	10	available	available	JJ
cord-263862-zzys31e9	87	11	ELISA	ELISA	NNP
cord-263862-zzys31e9	87	12	kit	kit	NN
cord-263862-zzys31e9	87	13	as	as	IN
cord-263862-zzys31e9	87	14	instructed	instruct	VBN
cord-263862-zzys31e9	87	15	(	(	-LRB-
cord-263862-zzys31e9	87	16	Endogen	Endogen	NNP
cord-263862-zzys31e9	87	17	,	,	,
cord-263862-zzys31e9	87	18	Rockford	Rockford	NNP
cord-263862-zzys31e9	87	19	,	,	,
cord-263862-zzys31e9	87	20	IL	IL	NNP
cord-263862-zzys31e9	87	21	)	)	-RRB-
cord-263862-zzys31e9	87	22	.	.	.
cord-263862-zzys31e9	88	1	The	the	DT
cord-263862-zzys31e9	88	2	detection	detection	NN
cord-263862-zzys31e9	88	3	range	range	NN
cord-263862-zzys31e9	88	4	for	for	IN
cord-263862-zzys31e9	88	5	this	this	DT
cord-263862-zzys31e9	88	6	assay	assay	NN
cord-263862-zzys31e9	88	7	was	be	VBD
cord-263862-zzys31e9	88	8	12.5	12.5	CD
cord-263862-zzys31e9	88	9	-	-	SYM
cord-263862-zzys31e9	88	10	500	500	CD
cord-263862-zzys31e9	88	11	pg	pg	NN
cord-263862-zzys31e9	88	12	/	/	SYM
cord-263862-zzys31e9	88	13	ml	ml	NN
cord-263862-zzys31e9	88	14	.	.	.
cord-263862-zzys31e9	89	1	In	in	IN
cord-263862-zzys31e9	89	2	some	some	DT
cord-263862-zzys31e9	89	3	experiments	experiment	NNS
cord-263862-zzys31e9	89	4	cytokine	cytokine	NN
cord-263862-zzys31e9	89	5	determinations	determination	NNS
cord-263862-zzys31e9	89	6	were	be	VBD
cord-263862-zzys31e9	89	7	performed	perform	VBN
cord-263862-zzys31e9	89	8	using	use	VBG
cord-263862-zzys31e9	89	9	the	the	DT
cord-263862-zzys31e9	89	10	cytometric	cytometric	NNP
cord-263862-zzys31e9	89	11	bead	bead	NN
cord-263862-zzys31e9	89	12	array	array	NN
cord-263862-zzys31e9	89	13	(	(	-LRB-
cord-263862-zzys31e9	89	14	CBA	CBA	NNP
cord-263862-zzys31e9	89	15	)	)	-RRB-
cord-263862-zzys31e9	89	16	mouse	mouse	NN
cord-263862-zzys31e9	89	17	inflammation	inflammation	NN
cord-263862-zzys31e9	89	18	kit	kit	NN
cord-263862-zzys31e9	89	19	from	from	IN
cord-263862-zzys31e9	89	20	BD	BD	NNP
cord-263862-zzys31e9	89	21	Pharmingen	Pharmingen	NNP
cord-263862-zzys31e9	89	22	as	as	IN
cord-263862-zzys31e9	89	23	described	describe	VBN
cord-263862-zzys31e9	89	24	by	by	IN
cord-263862-zzys31e9	89	25	the	the	DT
cord-263862-zzys31e9	89	26	manufacturer	manufacturer	NN
cord-263862-zzys31e9	89	27	.	.	.
cord-263862-zzys31e9	90	1	Samples	sample	NNS
cord-263862-zzys31e9	90	2	were	be	VBD
cord-263862-zzys31e9	90	3	acquired	acquire	VBN
cord-263862-zzys31e9	90	4	on	on	IN
cord-263862-zzys31e9	90	5	a	a	DT
cord-263862-zzys31e9	90	6	BD	BD	NNP
cord-263862-zzys31e9	90	7	FACscalibur	FACscalibur	NNS
cord-263862-zzys31e9	90	8	and	and	CC
cord-263862-zzys31e9	90	9	analysed	analyse	VBD
cord-263862-zzys31e9	90	10	with	with	IN
cord-263862-zzys31e9	90	11	Cellquest	Cellquest	NNP
cord-263862-zzys31e9	90	12	Pro	pro	JJ
cord-263862-zzys31e9	90	13	TM	TM	NNP
cord-263862-zzys31e9	90	14	software	software	NN
cord-263862-zzys31e9	90	15	.	.	.
cord-263862-zzys31e9	91	1	The	the	DT
cord-263862-zzys31e9	91	2	detection	detection	NN
cord-263862-zzys31e9	91	3	range	range	NN
cord-263862-zzys31e9	91	4	for	for	IN
cord-263862-zzys31e9	91	5	all	all	DT
cord-263862-zzys31e9	91	6	cytokines	cytokine	NNS
cord-263862-zzys31e9	91	7	by	by	IN
cord-263862-zzys31e9	91	8	this	this	DT
cord-263862-zzys31e9	91	9	method	method	NN
cord-263862-zzys31e9	91	10	was	be	VBD
cord-263862-zzys31e9	91	11	39	39	CD
cord-263862-zzys31e9	91	12	-	-	SYM
cord-263862-zzys31e9	91	13	5000	5000	CD
cord-263862-zzys31e9	91	14	pg	pg	NN
cord-263862-zzys31e9	91	15	/	/	SYM
cord-263862-zzys31e9	91	16	ml	ml	NN
cord-263862-zzys31e9	91	17	.	.	.
cord-263862-zzys31e9	92	1	Bone	bone	NN
cord-263862-zzys31e9	92	2	-	-	HYPH
cord-263862-zzys31e9	92	3	marrow	marrow	NN
cord-263862-zzys31e9	92	4	was	be	VBD
cord-263862-zzys31e9	92	5	flushed	flush	VBN
cord-263862-zzys31e9	92	6	from	from	IN
cord-263862-zzys31e9	92	7	the	the	DT
cord-263862-zzys31e9	92	8	femurs	femur	NNS
cord-263862-zzys31e9	92	9	and	and	CC
cord-263862-zzys31e9	92	10	tibiae	tibia	NNS
cord-263862-zzys31e9	92	11	of	of	IN
cord-263862-zzys31e9	92	12	5	5	CD
cord-263862-zzys31e9	92	13	Balb	Balb	NNP
cord-263862-zzys31e9	92	14	/	/	SYM
cord-263862-zzys31e9	92	15	c	c	NNP
cord-263862-zzys31e9	92	16	ByJ	ByJ	NNP
cord-263862-zzys31e9	92	17	mice	mouse	NNS
cord-263862-zzys31e9	92	18	using	use	VBG
cord-263862-zzys31e9	92	19	cold	cold	JJ
cord-263862-zzys31e9	92	20	complete	complete	JJ
cord-263862-zzys31e9	92	21	RPMI	RPMI	NNP
cord-263862-zzys31e9	92	22	.	.	.
cord-263862-zzys31e9	93	1	Cells	cell	NNS
cord-263862-zzys31e9	93	2	were	be	VBD
cord-263862-zzys31e9	93	3	washed	wash	VBN
cord-263862-zzys31e9	93	4	and	and	CC
cord-263862-zzys31e9	93	5	re	re	NNS
cord-263862-zzys31e9	93	6	-	-	VBN
cord-263862-zzys31e9	93	7	suspended	suspend	VBN
cord-263862-zzys31e9	93	8	in	in	IN
cord-263862-zzys31e9	93	9	complete	complete	JJ
cord-263862-zzys31e9	93	10	RPMI	RPMI	NNP
cord-263862-zzys31e9	93	11	supplemented	supplement	VBN
cord-263862-zzys31e9	93	12	with	with	IN
cord-263862-zzys31e9	93	13	GM	GM	NNP
cord-263862-zzys31e9	93	14	-	-	HYPH
cord-263862-zzys31e9	93	15	CSF	CSF	NNP
cord-263862-zzys31e9	93	16	(	(	-LRB-
cord-263862-zzys31e9	93	17	5	5	CD
cord-263862-zzys31e9	93	18	ng	ng	NNP
cord-263862-zzys31e9	93	19	/	/	SYM
cord-263862-zzys31e9	93	20	ml	ml	XX
cord-263862-zzys31e9	93	21	,	,	,
cord-263862-zzys31e9	93	22	R&D	R&D	NNP
cord-263862-zzys31e9	93	23	Systems	Systems	NNP
cord-263862-zzys31e9	93	24	)	)	-RRB-
cord-263862-zzys31e9	93	25	.	.	.
cord-263862-zzys31e9	94	1	On	on	IN
cord-263862-zzys31e9	94	2	day	day	NN
cord-263862-zzys31e9	94	3	3	3	CD
cord-263862-zzys31e9	94	4	fresh	fresh	JJ
cord-263862-zzys31e9	94	5	media	medium	NNS
cord-263862-zzys31e9	94	6	containing	contain	VBG
cord-263862-zzys31e9	94	7	GM	GM	NNP
cord-263862-zzys31e9	94	8	-	-	HYPH
cord-263862-zzys31e9	94	9	CSF	CSF	NNP
cord-263862-zzys31e9	94	10	was	be	VBD
cord-263862-zzys31e9	94	11	added	add	VBN
cord-263862-zzys31e9	94	12	to	to	IN
cord-263862-zzys31e9	94	13	the	the	DT
cord-263862-zzys31e9	94	14	adherent	adherent	JJ
cord-263862-zzys31e9	94	15	cells	cell	NNS
cord-263862-zzys31e9	94	16	.	.	.
cord-263862-zzys31e9	95	1	On	on	IN
cord-263862-zzys31e9	95	2	day	day	NN
cord-263862-zzys31e9	95	3	7	7	CD
cord-263862-zzys31e9	95	4	,	,	,
cord-263862-zzys31e9	95	5	cells	cell	NNS
cord-263862-zzys31e9	95	6	were	be	VBD
cord-263862-zzys31e9	95	7	washed	wash	VBN
cord-263862-zzys31e9	95	8	,	,	,
cord-263862-zzys31e9	95	9	phenotyped	phenotype	VBN
cord-263862-zzys31e9	95	10	by	by	IN
cord-263862-zzys31e9	95	11	flow	flow	NN
cord-263862-zzys31e9	95	12	cytometry	cytometry	NN
cord-263862-zzys31e9	95	13	and	and	CC
cord-263862-zzys31e9	95	14	if	if	IN
cord-263862-zzys31e9	95	15	>	>	XX
cord-263862-zzys31e9	95	16	80	80	CD
cord-263862-zzys31e9	95	17	%	%	NN
cord-263862-zzys31e9	95	18	of	of	IN
cord-263862-zzys31e9	95	19	the	the	DT
cord-263862-zzys31e9	95	20	cells	cell	NNS
cord-263862-zzys31e9	95	21	were	be	VBD
cord-263862-zzys31e9	95	22	CD11c	CD11c	NNP
cord-263862-zzys31e9	96	1	+	+	CC
cord-263862-zzys31e9	96	2	they	-PRON-	PRP
cord-263862-zzys31e9	96	3	were	be	VBD
cord-263862-zzys31e9	96	4	then	then	RB
cord-263862-zzys31e9	96	5	used	use	VBN
cord-263862-zzys31e9	96	6	for	for	IN
cord-263862-zzys31e9	96	7	experiments	experiment	NNS
cord-263862-zzys31e9	96	8	.	.	.
cord-263862-zzys31e9	97	1	BMDCs	bmdc	NNS
cord-263862-zzys31e9	97	2	were	be	VBD
cord-263862-zzys31e9	97	3	cultured	culture	VBN
cord-263862-zzys31e9	97	4	at	at	IN
cord-263862-zzys31e9	97	5	a	a	DT
cord-263862-zzys31e9	97	6	concentration	concentration	NN
cord-263862-zzys31e9	97	7	of	of	IN
cord-263862-zzys31e9	97	8	1	1	CD
cord-263862-zzys31e9	97	9	×	×	NN
cord-263862-zzys31e9	97	10	10	10	CD
cord-263862-zzys31e9	97	11	6	6	CD
cord-263862-zzys31e9	97	12	cells/	cells/	CD
cord-263862-zzys31e9	97	13	ml	ml	NNS
cord-263862-zzys31e9	97	14	in	in	IN
cord-263862-zzys31e9	97	15	complete	complete	JJ
cord-263862-zzys31e9	97	16	RPMI	RPMI	NNP
cord-263862-zzys31e9	97	17	for	for	IN
cord-263862-zzys31e9	97	18	24	24	CD
cord-263862-zzys31e9	97	19	h	h	NN
cord-263862-zzys31e9	97	20	in	in	IN
cord-263862-zzys31e9	97	21	the	the	DT
cord-263862-zzys31e9	97	22	presence	presence	NN
cord-263862-zzys31e9	97	23	of	of	IN
cord-263862-zzys31e9	97	24	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	97	25	at	at	IN
cord-263862-zzys31e9	97	26	a	a	DT
cord-263862-zzys31e9	97	27	MOI	moi	NN
cord-263862-zzys31e9	97	28	of	of	IN
cord-263862-zzys31e9	97	29	0.2	0.2	CD
cord-263862-zzys31e9	97	30	and	and	CC
cord-263862-zzys31e9	97	31	1	1	CD
cord-263862-zzys31e9	97	32	,	,	,
cord-263862-zzys31e9	97	33	or	or	CC
cord-263862-zzys31e9	97	34	the	the	DT
cord-263862-zzys31e9	97	35	equivalent	equivalent	JJ
cord-263862-zzys31e9	97	36	volume	volume	NN
cord-263862-zzys31e9	97	37	of	of	IN
cord-263862-zzys31e9	97	38	Placebo	Placebo	NNP
cord-263862-zzys31e9	97	39	.	.	.
cord-263862-zzys31e9	98	1	Cells	cell	NNS
cord-263862-zzys31e9	98	2	cultured	cultured	JJ
cord-263862-zzys31e9	98	3	in	in	IN
cord-263862-zzys31e9	98	4	medium	medium	NN
cord-263862-zzys31e9	98	5	alone	alone	RB
cord-263862-zzys31e9	98	6	were	be	VBD
cord-263862-zzys31e9	98	7	used	use	VBN
cord-263862-zzys31e9	98	8	as	as	IN
cord-263862-zzys31e9	98	9	a	a	DT
cord-263862-zzys31e9	98	10	negative	negative	JJ
cord-263862-zzys31e9	98	11	control	control	NN
cord-263862-zzys31e9	98	12	and	and	CC
cord-263862-zzys31e9	98	13	cells	cell	NNS
cord-263862-zzys31e9	98	14	cultured	culture	VBN
cord-263862-zzys31e9	98	15	with	with	IN
cord-263862-zzys31e9	98	16	a	a	DT
cord-263862-zzys31e9	98	17	Toll	toll	NN
cord-263862-zzys31e9	98	18	like	like	IN
cord-263862-zzys31e9	98	19	receptor	receptor	NN
cord-263862-zzys31e9	98	20	(	(	-LRB-
cord-263862-zzys31e9	98	21	TLR	TLR	NNP
cord-263862-zzys31e9	98	22	)	)	-RRB-
cord-263862-zzys31e9	98	23	4	4	CD
cord-263862-zzys31e9	98	24	agonist	agonist	NN
cord-263862-zzys31e9	98	25	(	(	-LRB-
cord-263862-zzys31e9	98	26	Sanofi	Sanofi	NNP
cord-263862-zzys31e9	98	27	-	-	HYPH
cord-263862-zzys31e9	98	28	Pasteur	Pasteur	NNP
cord-263862-zzys31e9	98	29	)	)	-RRB-
cord-263862-zzys31e9	98	30	at	at	IN
cord-263862-zzys31e9	98	31	a	a	DT
cord-263862-zzys31e9	98	32	concentration	concentration	NN
cord-263862-zzys31e9	98	33	of	of	IN
cord-263862-zzys31e9	98	34	0.1	0.1	CD
cord-263862-zzys31e9	98	35	g	g	NN
cord-263862-zzys31e9	98	36	/	/	SYM
cord-263862-zzys31e9	98	37	ml	ml	XX
cord-263862-zzys31e9	98	38	,	,	,
cord-263862-zzys31e9	98	39	as	as	IN
cord-263862-zzys31e9	98	40	a	a	DT
cord-263862-zzys31e9	98	41	positive	positive	JJ
cord-263862-zzys31e9	98	42	control	control	NN
cord-263862-zzys31e9	98	43	.	.	.
cord-263862-zzys31e9	99	1	Cells	cell	NNS
cord-263862-zzys31e9	99	2	were	be	VBD
cord-263862-zzys31e9	99	3	washed	wash	VBN
cord-263862-zzys31e9	99	4	,	,	,
cord-263862-zzys31e9	99	5	re	re	NNS
cord-263862-zzys31e9	99	6	-	-	VBN
cord-263862-zzys31e9	99	7	suspended	suspend	VBN
cord-263862-zzys31e9	99	8	in	in	IN
cord-263862-zzys31e9	99	9	PBS	PBS	NNP
cord-263862-zzys31e9	99	10	with	with	IN
cord-263862-zzys31e9	99	11	2	2	CD
cord-263862-zzys31e9	99	12	%	%	NN
cord-263862-zzys31e9	99	13	FCS	FCS	NNP
cord-263862-zzys31e9	99	14	and	and	CC
cord-263862-zzys31e9	99	15	0.01	0.01	CD
cord-263862-zzys31e9	99	16	%	%	NN
cord-263862-zzys31e9	99	17	NaN	NaN	NNP
cord-263862-zzys31e9	99	18	3	3	CD
cord-263862-zzys31e9	99	19	;	;	:
cord-263862-zzys31e9	99	20	labelled	label	VBN
cord-263862-zzys31e9	99	21	with	with	IN
cord-263862-zzys31e9	99	22	mAbs	mAbs	NNP
cord-263862-zzys31e9	99	23	specific	specific	JJ
cord-263862-zzys31e9	99	24	for	for	IN
cord-263862-zzys31e9	99	25	CD3	CD3	NNP
cord-263862-zzys31e9	99	26	,	,	,
cord-263862-zzys31e9	99	27	CD4	CD4	NNP
cord-263862-zzys31e9	99	28	,	,	,
cord-263862-zzys31e9	99	29	CD8	CD8	NNP
cord-263862-zzys31e9	99	30	,	,	,
cord-263862-zzys31e9	99	31	CD19	CD19	NNP
cord-263862-zzys31e9	99	32	,	,	,
cord-263862-zzys31e9	99	33	CD11c	CD11c	NNP
cord-263862-zzys31e9	99	34	,	,	,
cord-263862-zzys31e9	99	35	CD40	CD40	NNP
cord-263862-zzys31e9	99	36	,	,	,
cord-263862-zzys31e9	99	37	CD80	CD80	NNP
cord-263862-zzys31e9	99	38	,	,	,
cord-263862-zzys31e9	99	39	and	and	CC
cord-263862-zzys31e9	99	40	CD86	CD86	NNP
cord-263862-zzys31e9	99	41	,	,	,
cord-263862-zzys31e9	99	42	with	with	IN
cord-263862-zzys31e9	99	43	the	the	DT
cord-263862-zzys31e9	99	44	appropriate	appropriate	JJ
cord-263862-zzys31e9	99	45	isotype	isotype	NN
cord-263862-zzys31e9	99	46	controls	control	NNS
cord-263862-zzys31e9	99	47	(	(	-LRB-
cord-263862-zzys31e9	99	48	all	all	DT
cord-263862-zzys31e9	99	49	from	from	IN
cord-263862-zzys31e9	99	50	BD	BD	NNP
cord-263862-zzys31e9	99	51	PharMingen	PharMingen	NNP
cord-263862-zzys31e9	99	52	)	)	-RRB-
cord-263862-zzys31e9	99	53	.	.	.
cord-263862-zzys31e9	100	1	Cells	cell	NNS
cord-263862-zzys31e9	100	2	were	be	VBD
cord-263862-zzys31e9	100	3	acquired	acquire	VBN
cord-263862-zzys31e9	100	4	using	use	VBG
cord-263862-zzys31e9	100	5	a	a	DT
cord-263862-zzys31e9	100	6	FACScalibur	facscalibur	NN
cord-263862-zzys31e9	100	7	(	(	-LRB-
cord-263862-zzys31e9	100	8	BD	BD	NNP
cord-263862-zzys31e9	100	9	)	)	-RRB-
cord-263862-zzys31e9	100	10	and	and	CC
cord-263862-zzys31e9	100	11	results	result	NNS
cord-263862-zzys31e9	100	12	analyzed	analyze	VBD
cord-263862-zzys31e9	100	13	using	use	VBG
cord-263862-zzys31e9	100	14	CellQuest	CellQuest	NNP
cord-263862-zzys31e9	100	15	Pro	pro	JJ
cord-263862-zzys31e9	100	16	TM	TM	NNP
cord-263862-zzys31e9	100	17	Software	software	NN
cord-263862-zzys31e9	100	18	(	(	-LRB-
cord-263862-zzys31e9	100	19	BD	BD	NNP
cord-263862-zzys31e9	100	20	)	)	-RRB-
cord-263862-zzys31e9	100	21	.	.	.
cord-263862-zzys31e9	101	1	Cell	cell	NN
cord-263862-zzys31e9	101	2	death	death	NN
cord-263862-zzys31e9	101	3	analysis	analysis	NN
cord-263862-zzys31e9	101	4	of	of	IN
cord-263862-zzys31e9	101	5	either	either	DT
cord-263862-zzys31e9	101	6	human	human	JJ
cord-263862-zzys31e9	101	7	peripheral	peripheral	JJ
cord-263862-zzys31e9	101	8	blood	blood	NN
cord-263862-zzys31e9	101	9	mononuclear	mononuclear	NN
cord-263862-zzys31e9	101	10	cells	cell	NNS
cord-263862-zzys31e9	101	11	(	(	-LRB-
cord-263862-zzys31e9	101	12	PBMCs	pbmc	NNS
cord-263862-zzys31e9	101	13	)	)	-RRB-
cord-263862-zzys31e9	101	14	or	or	CC
cord-263862-zzys31e9	101	15	murine	murine	JJ
cord-263862-zzys31e9	101	16	BMDCs	bmdc	NNS
cord-263862-zzys31e9	101	17	was	be	VBD
cord-263862-zzys31e9	101	18	carried	carry	VBN
cord-263862-zzys31e9	101	19	out	out	RP
cord-263862-zzys31e9	101	20	using	use	VBG
cord-263862-zzys31e9	101	21	the	the	DT
cord-263862-zzys31e9	101	22	TACS	TACS	NNP
cord-263862-zzys31e9	101	23	Annexin	Annexin	NNP
cord-263862-zzys31e9	101	24	-	-	HYPH
cord-263862-zzys31e9	101	25	V	v	NN
cord-263862-zzys31e9	101	26	-	-	HYPH
cord-263862-zzys31e9	101	27	FITC	FITC	NNP
cord-263862-zzys31e9	101	28	Apoptosis	Apoptosis	NNP
cord-263862-zzys31e9	101	29	Detection	Detection	NNP
cord-263862-zzys31e9	101	30	Kit	kit	NN
cord-263862-zzys31e9	101	31	as	as	IN
cord-263862-zzys31e9	101	32	described	describe	VBN
cord-263862-zzys31e9	101	33	by	by	IN
cord-263862-zzys31e9	101	34	the	the	DT
cord-263862-zzys31e9	101	35	manufacturer	manufacturer	NN
cord-263862-zzys31e9	101	36	(	(	-LRB-
cord-263862-zzys31e9	101	37	R&D	R&D	NNP
cord-263862-zzys31e9	101	38	Systems	Systems	NNP
cord-263862-zzys31e9	101	39	)	)	-RRB-
cord-263862-zzys31e9	101	40	.	.	.
cord-263862-zzys31e9	102	1	All	all	DT
cord-263862-zzys31e9	102	2	results	result	NNS
cord-263862-zzys31e9	102	3	are	be	VBP
cord-263862-zzys31e9	102	4	presented	present	VBN
cord-263862-zzys31e9	102	5	as	as	IN
cord-263862-zzys31e9	102	6	mean	mean	JJ
cord-263862-zzys31e9	102	7	±	±	NNP
cord-263862-zzys31e9	102	8	S.E.M.	S.E.M.	NNP
cord-263862-zzys31e9	102	9	,	,	,
cord-263862-zzys31e9	102	10	unless	unless	IN
cord-263862-zzys31e9	102	11	otherwise	otherwise	RB
cord-263862-zzys31e9	102	12	indicated	indicate	VBN
cord-263862-zzys31e9	102	13	.	.	.
cord-263862-zzys31e9	103	1	Differences	difference	NNS
cord-263862-zzys31e9	103	2	between	between	IN
cord-263862-zzys31e9	103	3	the	the	DT
cord-263862-zzys31e9	103	4	means	mean	NNS
cord-263862-zzys31e9	103	5	of	of	IN
cord-263862-zzys31e9	103	6	multiple	multiple	JJ
cord-263862-zzys31e9	103	7	groups	group	NNS
cord-263862-zzys31e9	103	8	in	in	IN
cord-263862-zzys31e9	103	9	an	an	DT
cord-263862-zzys31e9	103	10	experiment	experiment	NN
cord-263862-zzys31e9	103	11	were	be	VBD
cord-263862-zzys31e9	103	12	analysed	analyse	VBN
cord-263862-zzys31e9	103	13	using	use	VBG
cord-263862-zzys31e9	103	14	one	one	CD
cord-263862-zzys31e9	103	15	-	-	HYPH
cord-263862-zzys31e9	103	16	way	way	NN
cord-263862-zzys31e9	103	17	ANOVA	anova	NN
cord-263862-zzys31e9	103	18	analysis	analysis	NN
cord-263862-zzys31e9	103	19	of	of	IN
cord-263862-zzys31e9	103	20	variance	variance	NN
cord-263862-zzys31e9	103	21	.	.	.
cord-263862-zzys31e9	104	1	In	in	IN
cord-263862-zzys31e9	104	2	the	the	DT
cord-263862-zzys31e9	104	3	case	case	NN
cord-263862-zzys31e9	104	4	where	where	WRB
cord-263862-zzys31e9	104	5	only	only	RB
cord-263862-zzys31e9	104	6	two	two	CD
cord-263862-zzys31e9	104	7	groups	group	NNS
cord-263862-zzys31e9	104	8	are	be	VBP
cord-263862-zzys31e9	104	9	being	be	VBG
cord-263862-zzys31e9	104	10	considered	consider	VBN
cord-263862-zzys31e9	104	11	results	result	NNS
cord-263862-zzys31e9	104	12	were	be	VBD
cord-263862-zzys31e9	104	13	analysed	analyse	VBN
cord-263862-zzys31e9	104	14	using	use	VBG
cord-263862-zzys31e9	104	15	a	a	DT
cord-263862-zzys31e9	104	16	two	two	CD
cord-263862-zzys31e9	104	17	-	-	HYPH
cord-263862-zzys31e9	104	18	tailed	tailed	JJ
cord-263862-zzys31e9	104	19	independent	independent	JJ
cord-263862-zzys31e9	104	20	variable	variable	NN
cord-263862-zzys31e9	104	21	Student	Student	NNP
cord-263862-zzys31e9	104	22	's	's	POS
cord-263862-zzys31e9	104	23	T	t	NN
cord-263862-zzys31e9	104	24	test	test	NN
cord-263862-zzys31e9	104	25	.	.	.
cord-263862-zzys31e9	105	1	All	all	DT
cord-263862-zzys31e9	105	2	analysis	analysis	NN
cord-263862-zzys31e9	105	3	was	be	VBD
cord-263862-zzys31e9	105	4	performed	perform	VBN
cord-263862-zzys31e9	105	5	using	use	VBG
cord-263862-zzys31e9	105	6	StatView	StatView	NNP
cord-263862-zzys31e9	105	7	Software	Software	NNP
cord-263862-zzys31e9	105	8	(	(	-LRB-
cord-263862-zzys31e9	105	9	SAS	SAS	NNP
cord-263862-zzys31e9	105	10	,	,	,
cord-263862-zzys31e9	105	11	Cary	Cary	NNP
cord-263862-zzys31e9	105	12	,	,	,
cord-263862-zzys31e9	105	13	NC	NC	NNP
cord-263862-zzys31e9	105	14	)	)	-RRB-
cord-263862-zzys31e9	105	15	.	.	.
cord-263862-zzys31e9	106	1	p	p	LS
cord-263862-zzys31e9	106	2	-	-	HYPH
cord-263862-zzys31e9	106	3	Values	value	NNS
cord-263862-zzys31e9	106	4	<	<	XX
cord-263862-zzys31e9	106	5	0.05	0.05	CD
cord-263862-zzys31e9	106	6	were	be	VBD
cord-263862-zzys31e9	106	7	considered	consider	VBN
cord-263862-zzys31e9	106	8	significant	significant	JJ
cord-263862-zzys31e9	106	9	.	.	.
cord-263862-zzys31e9	107	1	Groups	group	NNS
cord-263862-zzys31e9	107	2	of	of	IN
cord-263862-zzys31e9	107	3	Balb	Balb	NNP
cord-263862-zzys31e9	107	4	/	/	SYM
cord-263862-zzys31e9	107	5	c	c	NN
cord-263862-zzys31e9	107	6	mice	mouse	NNS
cord-263862-zzys31e9	107	7	were	be	VBD
cord-263862-zzys31e9	107	8	immunised	immunise	VBN
cord-263862-zzys31e9	107	9	i.m	i.m	NNP
cord-263862-zzys31e9	107	10	.	.	.
cord-263862-zzys31e9	108	1	with	with	IN
cord-263862-zzys31e9	108	2	either	either	DT
cord-263862-zzys31e9	108	3	antigen	antigen	NN
cord-263862-zzys31e9	108	4	alone	alone	JJ
cord-263862-zzys31e9	108	5	(	(	-LRB-
cord-263862-zzys31e9	108	6	Tat	Tat	NNP
cord-263862-zzys31e9	108	7	or	or	CC
cord-263862-zzys31e9	108	8	gB	gB	NNP
cord-263862-zzys31e9	108	9	)	)	-RRB-
cord-263862-zzys31e9	108	10	or	or	CC
cord-263862-zzys31e9	108	11	in	in	IN
cord-263862-zzys31e9	108	12	combination	combination	NN
cord-263862-zzys31e9	108	13	with	with	IN
cord-263862-zzys31e9	108	14	Placebo	Placebo	NNP
cord-263862-zzys31e9	108	15	or	or	CC
cord-263862-zzys31e9	108	16	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	108	17	.	.	.
cord-263862-zzys31e9	109	1	Mice	mouse	NNS
cord-263862-zzys31e9	109	2	received	receive	VBD
cord-263862-zzys31e9	109	3	a	a	DT
cord-263862-zzys31e9	109	4	booster	booster	NN
cord-263862-zzys31e9	109	5	immunisation	immunisation	NN
cord-263862-zzys31e9	109	6	after	after	IN
cord-263862-zzys31e9	109	7	3	3	CD
cord-263862-zzys31e9	109	8	weeks	week	NNS
cord-263862-zzys31e9	109	9	,	,	,
cord-263862-zzys31e9	109	10	and	and	CC
cord-263862-zzys31e9	109	11	were	be	VBD
cord-263862-zzys31e9	109	12	sacrificed	sacrifice	VBN
cord-263862-zzys31e9	109	13	2	2	CD
cord-263862-zzys31e9	109	14	weeks	week	NNS
cord-263862-zzys31e9	109	15	later	later	RB
cord-263862-zzys31e9	109	16	in	in	IN
cord-263862-zzys31e9	109	17	order	order	NN
cord-263862-zzys31e9	109	18	to	to	TO
cord-263862-zzys31e9	109	19	investigate	investigate	VB
cord-263862-zzys31e9	109	20	antigen	antigen	NN
cord-263862-zzys31e9	109	21	-	-	HYPH
cord-263862-zzys31e9	109	22	specific	specific	JJ
cord-263862-zzys31e9	109	23	immune	immune	JJ
cord-263862-zzys31e9	109	24	responses	response	NNS
cord-263862-zzys31e9	109	25	.	.	.
cord-263862-zzys31e9	110	1	Titres	titre	NNS
cord-263862-zzys31e9	110	2	of	of	IN
cord-263862-zzys31e9	110	3	antigen	antigen	NN
cord-263862-zzys31e9	110	4	-	-	HYPH
cord-263862-zzys31e9	110	5	specific	specific	JJ
cord-263862-zzys31e9	110	6	IgG	igg	NN
cord-263862-zzys31e9	110	7	and	and	CC
cord-263862-zzys31e9	110	8	IgG1	IgG1	NNP
cord-263862-zzys31e9	110	9	/	/	,
cord-263862-zzys31e9	110	10	IgG2a	IgG2a	NNP
cord-263862-zzys31e9	110	11	were	be	VBD
cord-263862-zzys31e9	110	12	determined	determine	VBN
cord-263862-zzys31e9	110	13	by	by	IN
cord-263862-zzys31e9	110	14	ELISA	ELISA	NNP
cord-263862-zzys31e9	110	15	.	.	.
cord-263862-zzys31e9	111	1	The	the	DT
cord-263862-zzys31e9	111	2	levels	level	NNS
cord-263862-zzys31e9	111	3	of	of	IN
cord-263862-zzys31e9	111	4	gB	gB	NNP
cord-263862-zzys31e9	111	5	specific	specific	JJ
cord-263862-zzys31e9	111	6	IgG	igg	NN
cord-263862-zzys31e9	111	7	observed	observe	VBD
cord-263862-zzys31e9	111	8	in	in	IN
cord-263862-zzys31e9	111	9	the	the	DT
cord-263862-zzys31e9	111	10	group	group	NN
cord-263862-zzys31e9	111	11	who	who	WP
cord-263862-zzys31e9	111	12	received	receive	VBD
cord-263862-zzys31e9	111	13	gB	gB	NNP
cord-263862-zzys31e9	111	14	and	and	CC
cord-263862-zzys31e9	111	15	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	111	16	were	be	VBD
cord-263862-zzys31e9	111	17	higher	high	JJR
cord-263862-zzys31e9	111	18	than	than	IN
cord-263862-zzys31e9	111	19	both	both	CC
cord-263862-zzys31e9	111	20	the	the	DT
cord-263862-zzys31e9	111	21	group	group	NN
cord-263862-zzys31e9	111	22	that	that	WDT
cord-263862-zzys31e9	111	23	received	receive	VBD
cord-263862-zzys31e9	111	24	gB	gB	NNP
cord-263862-zzys31e9	111	25	alone	alone	RB
cord-263862-zzys31e9	111	26	,	,	,
cord-263862-zzys31e9	111	27	and	and	CC
cord-263862-zzys31e9	111	28	the	the	DT
cord-263862-zzys31e9	111	29	group	group	NN
cord-263862-zzys31e9	111	30	immunised	immunise	VBN
cord-263862-zzys31e9	111	31	with	with	IN
cord-263862-zzys31e9	111	32	gB	gB	NNP
cord-263862-zzys31e9	111	33	and	and	CC
cord-263862-zzys31e9	111	34	Placebo	Placebo	NNP
cord-263862-zzys31e9	111	35	(	(	-LRB-
cord-263862-zzys31e9	111	36	Fig	Fig	NNP
cord-263862-zzys31e9	111	37	.	.	.
cord-263862-zzys31e9	111	38	1A	1a	NN
cord-263862-zzys31e9	111	39	)	)	-RRB-
cord-263862-zzys31e9	111	40	.	.	.
cord-263862-zzys31e9	112	1	A	a	DT
cord-263862-zzys31e9	112	2	similar	similar	JJ
cord-263862-zzys31e9	112	3	increase	increase	NN
cord-263862-zzys31e9	112	4	in	in	IN
cord-263862-zzys31e9	112	5	antigen	antigen	NN
cord-263862-zzys31e9	112	6	-	-	HYPH
cord-263862-zzys31e9	112	7	specific	specific	JJ
cord-263862-zzys31e9	112	8	IgG	igg	NN
cord-263862-zzys31e9	112	9	was	be	VBD
cord-263862-zzys31e9	112	10	observed	observe	VBN
cord-263862-zzys31e9	112	11	when	when	WRB
cord-263862-zzys31e9	112	12	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	112	13	was	be	VBD
cord-263862-zzys31e9	112	14	co	co	VBN
cord-263862-zzys31e9	112	15	-	-	VBN
cord-263862-zzys31e9	112	16	injected	inject	VBN
cord-263862-zzys31e9	113	1	with	with	IN
cord-263862-zzys31e9	113	2	another	another	DT
cord-263862-zzys31e9	113	3	antigen	antigen	NN
cord-263862-zzys31e9	113	4	,	,	,
cord-263862-zzys31e9	113	5	Tat	Tat	NNP
cord-263862-zzys31e9	113	6	(	(	-LRB-
cord-263862-zzys31e9	113	7	Fig	fig	NN
cord-263862-zzys31e9	113	8	.	.	.
cord-263862-zzys31e9	113	9	1B	1b	CD
cord-263862-zzys31e9	113	10	)	)	-RRB-
cord-263862-zzys31e9	113	11	.	.	.
cord-263862-zzys31e9	114	1	Looking	look	VBG
cord-263862-zzys31e9	114	2	at	at	IN
cord-263862-zzys31e9	114	3	the	the	DT
cord-263862-zzys31e9	114	4	particular	particular	JJ
cord-263862-zzys31e9	114	5	subclasses	subclass	NNS
cord-263862-zzys31e9	114	6	of	of	IN
cord-263862-zzys31e9	114	7	IgG	IgG	NNP
cord-263862-zzys31e9	114	8	,	,	,
cord-263862-zzys31e9	114	9	the	the	DT
cord-263862-zzys31e9	114	10	addition	addition	NN
cord-263862-zzys31e9	114	11	of	of	IN
cord-263862-zzys31e9	114	12	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	114	13	to	to	IN
cord-263862-zzys31e9	114	14	the	the	DT
cord-263862-zzys31e9	114	15	antigens	antigen	NNS
cord-263862-zzys31e9	114	16	Tat	Tat	NNP
cord-263862-zzys31e9	114	17	or	or	CC
cord-263862-zzys31e9	114	18	gB	gB	NNP
cord-263862-zzys31e9	114	19	did	do	VBD
cord-263862-zzys31e9	114	20	not	not	RB
cord-263862-zzys31e9	114	21	cause	cause	VB
cord-263862-zzys31e9	114	22	an	an	DT
cord-263862-zzys31e9	114	23	increase	increase	NN
cord-263862-zzys31e9	114	24	in	in	IN
cord-263862-zzys31e9	114	25	the	the	DT
cord-263862-zzys31e9	114	26	levels	level	NNS
cord-263862-zzys31e9	114	27	of	of	IN
cord-263862-zzys31e9	114	28	antigen	antigen	NN
cord-263862-zzys31e9	114	29	-	-	HYPH
cord-263862-zzys31e9	114	30	specific	specific	JJ
cord-263862-zzys31e9	114	31	IgG1	igg1	FW
cord-263862-zzys31e9	114	32	(	(	-LRB-
cord-263862-zzys31e9	114	33	Fig	Fig	NNP
cord-263862-zzys31e9	114	34	.	.	.
cord-263862-zzys31e9	114	35	1C	1C	NNP
cord-263862-zzys31e9	114	36	and	and	CC
cord-263862-zzys31e9	114	37	D	D	NNP
cord-263862-zzys31e9	114	38	)	)	-RRB-
cord-263862-zzys31e9	114	39	.	.	.
cord-263862-zzys31e9	115	1	However	however	RB
cord-263862-zzys31e9	115	2	,	,	,
cord-263862-zzys31e9	115	3	a	a	DT
cord-263862-zzys31e9	115	4	2-fold	2-fold	CD
cord-263862-zzys31e9	115	5	increase	increase	NN
cord-263862-zzys31e9	115	6	was	be	VBD
cord-263862-zzys31e9	115	7	observed	observe	VBN
cord-263862-zzys31e9	115	8	in	in	IN
cord-263862-zzys31e9	115	9	the	the	DT
cord-263862-zzys31e9	115	10	levels	level	NNS
cord-263862-zzys31e9	115	11	of	of	IN
cord-263862-zzys31e9	115	12	anti	anti	JJ
cord-263862-zzys31e9	115	13	-	-	JJ
cord-263862-zzys31e9	115	14	gB	gb	JJ
cord-263862-zzys31e9	115	15	IgG2a	IgG2a	NNP
cord-263862-zzys31e9	115	16	in	in	IN
cord-263862-zzys31e9	115	17	mice	mouse	NNS
cord-263862-zzys31e9	115	18	that	that	WDT
cord-263862-zzys31e9	115	19	received	receive	VBD
cord-263862-zzys31e9	115	20	gB	gB	NNP
cord-263862-zzys31e9	115	21	and	and	CC
cord-263862-zzys31e9	115	22	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	115	23	compared	compare	VBN
cord-263862-zzys31e9	115	24	to	to	IN
cord-263862-zzys31e9	115	25	mice	mouse	NNS
cord-263862-zzys31e9	115	26	that	that	WDT
cord-263862-zzys31e9	115	27	received	receive	VBD
cord-263862-zzys31e9	115	28	gB	gB	NNP
cord-263862-zzys31e9	115	29	alone	alone	JJ
cord-263862-zzys31e9	116	1	(	(	-LRB-
cord-263862-zzys31e9	116	2	Fig	Fig	NNP
cord-263862-zzys31e9	116	3	.	.	.
cord-263862-zzys31e9	116	4	1E	1E	NNP
cord-263862-zzys31e9	116	5	)	)	-RRB-
cord-263862-zzys31e9	116	6	.	.	.
cord-263862-zzys31e9	117	1	A	a	DT
cord-263862-zzys31e9	117	2	similar	similar	JJ
cord-263862-zzys31e9	117	3	augmentation	augmentation	NN
cord-263862-zzys31e9	117	4	of	of	IN
cord-263862-zzys31e9	117	5	Tat	tat	NN
cord-263862-zzys31e9	117	6	-	-	HYPH
cord-263862-zzys31e9	117	7	specific	specific	JJ
cord-263862-zzys31e9	117	8	IgG2a	IgG2a	NNP
cord-263862-zzys31e9	117	9	was	be	VBD
cord-263862-zzys31e9	117	10	observed	observe	VBN
cord-263862-zzys31e9	117	11	in	in	IN
cord-263862-zzys31e9	117	12	the	the	DT
cord-263862-zzys31e9	117	13	groups	group	NNS
cord-263862-zzys31e9	117	14	of	of	IN
cord-263862-zzys31e9	117	15	mice	mouse	NNS
cord-263862-zzys31e9	117	16	that	that	WDT
cord-263862-zzys31e9	117	17	received	receive	VBD
cord-263862-zzys31e9	117	18	Tat	Tat	NNP
cord-263862-zzys31e9	117	19	and	and	CC
cord-263862-zzys31e9	117	20	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	117	21	compared	compare	VBN
cord-263862-zzys31e9	117	22	to	to	IN
cord-263862-zzys31e9	117	23	those	those	DT
cord-263862-zzys31e9	117	24	that	that	WDT
cord-263862-zzys31e9	117	25	received	receive	VBD
cord-263862-zzys31e9	117	26	either	either	CC
cord-263862-zzys31e9	117	27	Tat	Tat	NNP
cord-263862-zzys31e9	117	28	alone	alone	RB
cord-263862-zzys31e9	117	29	or	or	CC
cord-263862-zzys31e9	117	30	Tat	Tat	NNP
cord-263862-zzys31e9	117	31	and	and	CC
cord-263862-zzys31e9	117	32	Placebo	Placebo	NNP
cord-263862-zzys31e9	117	33	(	(	-LRB-
cord-263862-zzys31e9	117	34	Fig	Fig	NNP
cord-263862-zzys31e9	117	35	.	.	.
cord-263862-zzys31e9	117	36	1F	1F	NNP
cord-263862-zzys31e9	117	37	)	)	-RRB-
cord-263862-zzys31e9	117	38	.	.	.
cord-263862-zzys31e9	118	1	These	these	DT
cord-263862-zzys31e9	118	2	results	result	NNS
cord-263862-zzys31e9	118	3	clearly	clearly	RB
cord-263862-zzys31e9	118	4	show	show	VBP
cord-263862-zzys31e9	118	5	that	that	IN
cord-263862-zzys31e9	118	6	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	118	7	can	can	MD
cord-263862-zzys31e9	118	8	act	act	VB
cord-263862-zzys31e9	118	9	as	as	IN
cord-263862-zzys31e9	118	10	an	an	DT
cord-263862-zzys31e9	118	11	adjuvant	adjuvant	NN
cord-263862-zzys31e9	118	12	augmenting	augment	VBG
cord-263862-zzys31e9	118	13	antigen	antigen	NN
cord-263862-zzys31e9	118	14	-	-	HYPH
cord-263862-zzys31e9	118	15	specific	specific	JJ
cord-263862-zzys31e9	118	16	IgG2a	igg2a	JJ
cord-263862-zzys31e9	118	17	responses	response	NNS
cord-263862-zzys31e9	118	18	to	to	TO
cord-263862-zzys31e9	118	19	co	co	VB
cord-263862-zzys31e9	118	20	-	-	JJ
cord-263862-zzys31e9	118	21	injected	inject	VBN
cord-263862-zzys31e9	118	22	antigen	antigen	NN
cord-263862-zzys31e9	118	23	.	.	.
cord-263862-zzys31e9	119	1	Next	next	RB
cord-263862-zzys31e9	119	2	,	,	,
cord-263862-zzys31e9	119	3	we	-PRON-	PRP
cord-263862-zzys31e9	119	4	investigated	investigate	VBD
cord-263862-zzys31e9	119	5	the	the	DT
cord-263862-zzys31e9	119	6	effect	effect	NN
cord-263862-zzys31e9	119	7	of	of	IN
cord-263862-zzys31e9	119	8	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	119	9	on	on	IN
cord-263862-zzys31e9	119	10	the	the	DT
cord-263862-zzys31e9	119	11	cellular	cellular	JJ
cord-263862-zzys31e9	119	12	immune	immune	JJ
cord-263862-zzys31e9	119	13	response	response	NN
cord-263862-zzys31e9	119	14	to	to	TO
cord-263862-zzys31e9	119	15	co	co	VB
cord-263862-zzys31e9	119	16	-	-	JJ
cord-263862-zzys31e9	119	17	injected	inject	VBN
cord-263862-zzys31e9	119	18	antigen	antigen	NN
cord-263862-zzys31e9	119	19	.	.	.
cord-263862-zzys31e9	120	1	Groups	group	NNS
cord-263862-zzys31e9	120	2	of	of	IN
cord-263862-zzys31e9	120	3	10	10	CD
cord-263862-zzys31e9	120	4	Balb	Balb	NNP
cord-263862-zzys31e9	120	5	/	/	SYM
cord-263862-zzys31e9	120	6	c	c	NN
cord-263862-zzys31e9	120	7	mice	mouse	NNS
cord-263862-zzys31e9	120	8	were	be	VBD
cord-263862-zzys31e9	120	9	immunised	immunise	VBN
cord-263862-zzys31e9	120	10	with	with	IN
cord-263862-zzys31e9	120	11	Tat	Tat	NNP
cord-263862-zzys31e9	120	12	alone	alone	RB
cord-263862-zzys31e9	120	13	,	,	,
cord-263862-zzys31e9	120	14	Tat	Tat	NNP
cord-263862-zzys31e9	120	15	and	and	CC
cord-263862-zzys31e9	120	16	Placebo	Placebo	NNP
cord-263862-zzys31e9	120	17	or	or	CC
cord-263862-zzys31e9	120	18	Tat	Tat	NNP
cord-263862-zzys31e9	120	19	and	and	CC
cord-263862-zzys31e9	120	20	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	120	21	and	and	CC
cord-263862-zzys31e9	120	22	2	2	CD
cord-263862-zzys31e9	120	23	weeks	week	NNS
cord-263862-zzys31e9	120	24	after	after	IN
cord-263862-zzys31e9	120	25	a	a	DT
cord-263862-zzys31e9	120	26	booster	booster	NN
cord-263862-zzys31e9	120	27	immunisation	immunisation	NN
cord-263862-zzys31e9	120	28	the	the	DT
cord-263862-zzys31e9	120	29	mice	mouse	NNS
cord-263862-zzys31e9	120	30	were	be	VBD
cord-263862-zzys31e9	120	31	sacrificed	sacrifice	VBN
cord-263862-zzys31e9	120	32	and	and	CC
cord-263862-zzys31e9	120	33	their	-PRON-	PRP$
cord-263862-zzys31e9	120	34	spleen	spleen	NNS
cord-263862-zzys31e9	120	35	removed	remove	VBN
cord-263862-zzys31e9	120	36	to	to	TO
cord-263862-zzys31e9	120	37	analyse	analyse	VB
cord-263862-zzys31e9	120	38	the	the	DT
cord-263862-zzys31e9	120	39	cellular	cellular	JJ
cord-263862-zzys31e9	120	40	immune	immune	JJ
cord-263862-zzys31e9	120	41	responses	response	NNS
cord-263862-zzys31e9	120	42	.	.	.
cord-263862-zzys31e9	121	1	The	the	DT
cord-263862-zzys31e9	121	2	spleen	spleen	NN
cord-263862-zzys31e9	121	3	cells	cell	NNS
cord-263862-zzys31e9	121	4	were	be	VBD
cord-263862-zzys31e9	121	5	restimulated	restimulate	VBN
cord-263862-zzys31e9	121	6	in	in	IN
cord-263862-zzys31e9	121	7	vitro	vitro	FW
cord-263862-zzys31e9	121	8	and	and	CC
cord-263862-zzys31e9	121	9	the	the	DT
cord-263862-zzys31e9	121	10	numbers	number	NNS
cord-263862-zzys31e9	121	11	of	of	IN
cord-263862-zzys31e9	121	12	antigen	antigen	NN
cord-263862-zzys31e9	121	13	-	-	HYPH
cord-263862-zzys31e9	121	14	specific	specific	JJ
cord-263862-zzys31e9	121	15	IFN-	IFN-	NNP
cord-263862-zzys31e9	121	16	␥	␥	CD
cord-263862-zzys31e9	121	17	secreting	secrete	VBG
cord-263862-zzys31e9	121	18	cells	cell	NNS
cord-263862-zzys31e9	121	19	were	be	VBD
cord-263862-zzys31e9	121	20	determined	determine	VBN
cord-263862-zzys31e9	121	21	by	by	IN
cord-263862-zzys31e9	121	22	ELISPOT	ELISPOT	NNP
cord-263862-zzys31e9	121	23	(	(	-LRB-
cord-263862-zzys31e9	121	24	Fig	Fig	NNP
cord-263862-zzys31e9	121	25	.	.	.
cord-263862-zzys31e9	121	26	1	1	CD
cord-263862-zzys31e9	121	27	G	g	NN
cord-263862-zzys31e9	121	28	)	)	-RRB-
cord-263862-zzys31e9	121	29	.	.	.
cord-263862-zzys31e9	122	1	The	the	DT
cord-263862-zzys31e9	122	2	number	number	NN
cord-263862-zzys31e9	122	3	of	of	IN
cord-263862-zzys31e9	122	4	Tat	tat	NN
cord-263862-zzys31e9	122	5	-	-	HYPH
cord-263862-zzys31e9	122	6	specific	specific	JJ
cord-263862-zzys31e9	122	7	IFN-	IFN-	NNP
cord-263862-zzys31e9	122	8	␥	␥	CD
cord-263862-zzys31e9	122	9	secreting	secrete	VBG
cord-263862-zzys31e9	122	10	cells	cell	NNS
cord-263862-zzys31e9	122	11	in	in	IN
cord-263862-zzys31e9	122	12	the	the	DT
cord-263862-zzys31e9	122	13	groups	group	NNS
cord-263862-zzys31e9	122	14	of	of	IN
cord-263862-zzys31e9	122	15	mice	mouse	NNS
cord-263862-zzys31e9	122	16	that	that	WDT
cord-263862-zzys31e9	122	17	received	receive	VBD
cord-263862-zzys31e9	122	18	Tat	tat	NN
cord-263862-zzys31e9	122	19	alone	alone	JJ
cord-263862-zzys31e9	122	20	or	or	CC
cord-263862-zzys31e9	122	21	Tat	Tat	NNP
cord-263862-zzys31e9	122	22	and	and	CC
cord-263862-zzys31e9	122	23	Placebo	Placebo	NNP
cord-263862-zzys31e9	122	24	were	be	VBD
cord-263862-zzys31e9	122	25	not	not	RB
cord-263862-zzys31e9	122	26	significantly	significantly	RB
cord-263862-zzys31e9	122	27	different	different	JJ
cord-263862-zzys31e9	122	28	from	from	IN
cord-263862-zzys31e9	122	29	background	background	NN
cord-263862-zzys31e9	122	30	levels	level	NNS
cord-263862-zzys31e9	122	31	(	(	-LRB-
cord-263862-zzys31e9	122	32	Fig	fig	NN
cord-263862-zzys31e9	122	33	.	.	.
cord-263862-zzys31e9	122	34	1	1	CD
cord-263862-zzys31e9	122	35	G	g	NN
cord-263862-zzys31e9	122	36	)	)	-RRB-
cord-263862-zzys31e9	122	37	.	.	.
cord-263862-zzys31e9	123	1	However	however	RB
cord-263862-zzys31e9	123	2	,	,	,
cord-263862-zzys31e9	123	3	Tat	tat	NN
cord-263862-zzys31e9	123	4	-	-	HYPH
cord-263862-zzys31e9	123	5	specific	specific	JJ
cord-263862-zzys31e9	123	6	IFN-	IFN-	NNP
cord-263862-zzys31e9	123	7	␥	␥	CD
cord-263862-zzys31e9	123	8	secreting	secrete	VBG
cord-263862-zzys31e9	123	9	cells	cell	NNS
cord-263862-zzys31e9	123	10	were	be	VBD
cord-263862-zzys31e9	123	11	detectable	detectable	JJ
cord-263862-zzys31e9	123	12	in	in	IN
cord-263862-zzys31e9	123	13	the	the	DT
cord-263862-zzys31e9	123	14	group	group	NN
cord-263862-zzys31e9	123	15	that	that	WDT
cord-263862-zzys31e9	123	16	received	receive	VBD
cord-263862-zzys31e9	123	17	Tat	Tat	NNP
cord-263862-zzys31e9	123	18	together	together	RB
cord-263862-zzys31e9	123	19	with	with	IN
cord-263862-zzys31e9	123	20	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	123	21	.	.	.
cord-263862-zzys31e9	124	1	IFN-	IFN-	NNP
cord-263862-zzys31e9	124	2	␥	␥	CD
cord-263862-zzys31e9	124	3	secreting	secrete	VBG
cord-263862-zzys31e9	124	4	cells	cell	NNS
cord-263862-zzys31e9	124	5	specific	specific	JJ
cord-263862-zzys31e9	124	6	for	for	IN
cord-263862-zzys31e9	124	7	the	the	DT
cord-263862-zzys31e9	124	8	vector	vector	NN
cord-263862-zzys31e9	124	9	itself	-PRON-	PRP
cord-263862-zzys31e9	124	10	(	(	-LRB-
cord-263862-zzys31e9	124	11	CpPP	CpPP	NNP
cord-263862-zzys31e9	124	12	)	)	-RRB-
cord-263862-zzys31e9	125	1	and	and	CC
cord-263862-zzys31e9	125	2	for	for	IN
cord-263862-zzys31e9	125	3	gag	gag	NN
cord-263862-zzys31e9	125	4	(	(	-LRB-
cord-263862-zzys31e9	125	5	encoded	encode	VBN
cord-263862-zzys31e9	125	6	by	by	IN
cord-263862-zzys31e9	125	7	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	125	8	)	)	-RRB-
cord-263862-zzys31e9	125	9	were	be	VBD
cord-263862-zzys31e9	125	10	detected	detect	VBN
cord-263862-zzys31e9	125	11	in	in	IN
cord-263862-zzys31e9	125	12	all	all	DT
cord-263862-zzys31e9	125	13	groups	group	NNS
cord-263862-zzys31e9	125	14	that	that	WDT
cord-263862-zzys31e9	125	15	received	receive	VBD
cord-263862-zzys31e9	125	16	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	125	17	(	(	-LRB-
cord-263862-zzys31e9	125	18	Fig	fig	NN
cord-263862-zzys31e9	125	19	.	.	.
cord-263862-zzys31e9	125	20	1	1	CD
cord-263862-zzys31e9	125	21	G	g	NN
cord-263862-zzys31e9	125	22	)	)	-RRB-
cord-263862-zzys31e9	125	23	.	.	.
cord-263862-zzys31e9	126	1	These	these	DT
cord-263862-zzys31e9	126	2	data	datum	NNS
cord-263862-zzys31e9	126	3	show	show	VBP
cord-263862-zzys31e9	126	4	that	that	IN
cord-263862-zzys31e9	126	5	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	126	6	augments	augment	VBZ
cord-263862-zzys31e9	126	7	both	both	CC
cord-263862-zzys31e9	126	8	humoral	humoral	JJ
cord-263862-zzys31e9	126	9	and	and	CC
cord-263862-zzys31e9	126	10	cellular	cellular	JJ
cord-263862-zzys31e9	126	11	type	type	NN
cord-263862-zzys31e9	126	12	1	1	CD
cord-263862-zzys31e9	126	13	responses	response	NNS
cord-263862-zzys31e9	126	14	to	to	IN
cord-263862-zzys31e9	126	15	coinjected	coinjected	JJ
cord-263862-zzys31e9	126	16	antigen	antigen	NNP
cord-263862-zzys31e9	126	17	.	.	.
cord-263862-zzys31e9	127	1	Two	two	CD
cord-263862-zzys31e9	127	2	major	major	JJ
cord-263862-zzys31e9	127	3	signalling	signal	VBG
cord-263862-zzys31e9	127	4	pathways	pathway	NNS
cord-263862-zzys31e9	127	5	participate	participate	VBP
cord-263862-zzys31e9	127	6	in	in	IN
cord-263862-zzys31e9	127	7	the	the	DT
cord-263862-zzys31e9	127	8	innate	innate	JJ
cord-263862-zzys31e9	127	9	immune	immune	JJ
cord-263862-zzys31e9	127	10	response	response	NN
cord-263862-zzys31e9	127	11	to	to	IN
cord-263862-zzys31e9	127	12	viral	viral	JJ
cord-263862-zzys31e9	127	13	DNA	dna	NN
cord-263862-zzys31e9	127	14	,	,	,
cord-263862-zzys31e9	127	15	namely	namely	RB
cord-263862-zzys31e9	127	16	,	,	,
cord-263862-zzys31e9	127	17	the	the	DT
cord-263862-zzys31e9	127	18	nuclear	nuclear	JJ
cord-263862-zzys31e9	127	19	factor	factor	NN
cord-263862-zzys31e9	127	20	-	-	HYPH
cord-263862-zzys31e9	127	21	B	b	NN
cord-263862-zzys31e9	127	22	(	(	-LRB-
cord-263862-zzys31e9	127	23	NF	NF	NNP
cord-263862-zzys31e9	127	24	-	-	HYPH
cord-263862-zzys31e9	127	25	B)-dependent	B)-dependent	NNP
cord-263862-zzys31e9	127	26	pathway	pathway	NN
cord-263862-zzys31e9	127	27	leading	lead	VBG
cord-263862-zzys31e9	127	28	to	to	IN
cord-263862-zzys31e9	127	29	inflammatory	inflammatory	JJ
cord-263862-zzys31e9	127	30	cytokine	cytokine	NN
cord-263862-zzys31e9	127	31	secretion	secretion	NN
cord-263862-zzys31e9	127	32	(	(	-LRB-
cord-263862-zzys31e9	127	33	including	include	VBG
cord-263862-zzys31e9	127	34	IL-12	IL-12	NNP
cord-263862-zzys31e9	127	35	and	and	CC
cord-263862-zzys31e9	127	36	IFN-	IFN-	NNP
cord-263862-zzys31e9	127	37	␥	␥	CD
cord-263862-zzys31e9	127	38	)	)	-RRB-
cord-263862-zzys31e9	127	39	and	and	CC
cord-263862-zzys31e9	127	40	the	the	DT
cord-263862-zzys31e9	127	41	type	type	NN
cord-263862-zzys31e9	127	42	I	-PRON-	PRP
cord-263862-zzys31e9	127	43	IFN	IFN	NNP
cord-263862-zzys31e9	127	44	-	-	HYPH
cord-263862-zzys31e9	127	45	dependent	dependent	JJ
cord-263862-zzys31e9	127	46	pathway	pathway	NN
cord-263862-zzys31e9	127	47	inducing	induce	VBG
cord-263862-zzys31e9	127	48	IFN-	IFN-	NNP
cord-263862-zzys31e9	128	1	␣	␣	NNP
cord-263862-zzys31e9	128	2	and	and	CC
cord-263862-zzys31e9	128	3	IFN	IFN	NNP
cord-263862-zzys31e9	128	4	-	-	HYPH
cord-263862-zzys31e9	128	5	regulated	regulate	VBN
cord-263862-zzys31e9	128	6	genes	gene	NNS
cord-263862-zzys31e9	128	7	[	[	-LRB-
cord-263862-zzys31e9	128	8	13	13	CD
cord-263862-zzys31e9	128	9	]	]	-RRB-
cord-263862-zzys31e9	128	10	.	.	.
cord-263862-zzys31e9	129	1	Therefore	therefore	RB
cord-263862-zzys31e9	129	2	,	,	,
cord-263862-zzys31e9	129	3	we	-PRON-	PRP
cord-263862-zzys31e9	129	4	wished	wish	VBD
cord-263862-zzys31e9	129	5	to	to	TO
cord-263862-zzys31e9	129	6	determine	determine	VB
cord-263862-zzys31e9	129	7	if	if	IN
cord-263862-zzys31e9	130	1	IFN-	IFN-	NNP
cord-263862-zzys31e9	130	2	␣	␣	NNP
cord-263862-zzys31e9	130	3	and/or	and/or	CC
cord-263862-zzys31e9	130	4	IFN-	IFN-	NNP
cord-263862-zzys31e9	130	5	␥	␥	NNPS
cord-263862-zzys31e9	130	6	were	be	VBD
cord-263862-zzys31e9	130	7	produced	produce	VBN
cord-263862-zzys31e9	130	8	in	in	IN
cord-263862-zzys31e9	130	9	vivo	vivo	NN
cord-263862-zzys31e9	130	10	following	follow	VBG
cord-263862-zzys31e9	130	11	an	an	DT
cord-263862-zzys31e9	130	12	injection	injection	NN
cord-263862-zzys31e9	130	13	of	of	IN
cord-263862-zzys31e9	130	14	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	130	15	.	.	.
cord-263862-zzys31e9	131	1	Groups	group	NNS
cord-263862-zzys31e9	131	2	of	of	IN
cord-263862-zzys31e9	131	3	Balb	Balb	NNP
cord-263862-zzys31e9	131	4	/	/	SYM
cord-263862-zzys31e9	131	5	c	c	NN
cord-263862-zzys31e9	131	6	mice	mouse	NNS
cord-263862-zzys31e9	131	7	were	be	VBD
cord-263862-zzys31e9	131	8	immunised	immunise	VBN
cord-263862-zzys31e9	131	9	simultaneously	simultaneously	RB
cord-263862-zzys31e9	131	10	by	by	IN
cord-263862-zzys31e9	131	11	the	the	DT
cord-263862-zzys31e9	131	12	i.m	i.m	NNP
cord-263862-zzys31e9	131	13	.	.	NNP
cord-263862-zzys31e9	131	14	route	route	NN
cord-263862-zzys31e9	131	15	with	with	IN
cord-263862-zzys31e9	131	16	1/10th	1/10th	CD
cord-263862-zzys31e9	131	17	of	of	IN
cord-263862-zzys31e9	131	18	the	the	DT
cord-263862-zzys31e9	131	19	human	human	JJ
cord-263862-zzys31e9	131	20	dose	dose	NN
cord-263862-zzys31e9	131	21	of	of	IN
cord-263862-zzys31e9	131	22	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	131	23	and	and	CC
cord-263862-zzys31e9	131	24	i.p	i.p	NNP
cord-263862-zzys31e9	131	25	.	.	NNP
cord-263862-zzys31e9	131	26	with	with	IN
cord-263862-zzys31e9	131	27	a	a	DT
cord-263862-zzys31e9	131	28	biotin	biotin	NN
cord-263862-zzys31e9	131	29	-	-	HYPH
cord-263862-zzys31e9	131	30	conjugated	conjugate	VBN
cord-263862-zzys31e9	131	31	anti	anti	JJ
cord-263862-zzys31e9	131	32	-	-	JJ
cord-263862-zzys31e9	131	33	IFN-	ifn-	JJ
cord-263862-zzys31e9	131	34	␥	␥	CD
cord-263862-zzys31e9	131	35	mAb	mab	NN
cord-263862-zzys31e9	131	36	,	,	,
cord-263862-zzys31e9	131	37	and	and	CC
cord-263862-zzys31e9	131	38	subsequently	subsequently	RB
cord-263862-zzys31e9	131	39	the	the	DT
cord-263862-zzys31e9	131	40	mice	mouse	NNS
cord-263862-zzys31e9	131	41	were	be	VBD
cord-263862-zzys31e9	131	42	bled	bleed	VBN
cord-263862-zzys31e9	131	43	at	at	IN
cord-263862-zzys31e9	131	44	various	various	JJ
cord-263862-zzys31e9	131	45	time	time	NN
cord-263862-zzys31e9	131	46	-	-	HYPH
cord-263862-zzys31e9	131	47	points	point	NNS
cord-263862-zzys31e9	131	48	after	after	IN
cord-263862-zzys31e9	131	49	immunisation	immunisation	NN
cord-263862-zzys31e9	131	50	.	.	.
cord-263862-zzys31e9	132	1	Levels	level	NNS
cord-263862-zzys31e9	132	2	of	of	IN
cord-263862-zzys31e9	132	3	the	the	DT
cord-263862-zzys31e9	132	4	IFN-	IFN-	NNP
cord-263862-zzys31e9	132	5	␥	␥	NNP
cord-263862-zzys31e9	132	6	:mAb	:mAb	NNP
cord-263862-zzys31e9	132	7	complex	complex	NN
cord-263862-zzys31e9	132	8	were	be	VBD
cord-263862-zzys31e9	132	9	determined	determine	VBN
cord-263862-zzys31e9	132	10	by	by	IN
cord-263862-zzys31e9	132	11	ELISA	ELISA	NNP
cord-263862-zzys31e9	132	12	.	.	.
cord-263862-zzys31e9	133	1	Significant	significant	JJ
cord-263862-zzys31e9	133	2	quantities	quantity	NNS
cord-263862-zzys31e9	133	3	of	of	IN
cord-263862-zzys31e9	133	4	IFN-	IFN-	NNP
cord-263862-zzys31e9	133	5	␥	␥	NNPS
cord-263862-zzys31e9	133	6	were	be	VBD
cord-263862-zzys31e9	133	7	detectable	detectable	JJ
cord-263862-zzys31e9	133	8	in	in	IN
cord-263862-zzys31e9	133	9	the	the	DT
cord-263862-zzys31e9	133	10	circulation	circulation	NN
cord-263862-zzys31e9	133	11	of	of	IN
cord-263862-zzys31e9	133	12	mice	mouse	NNS
cord-263862-zzys31e9	133	13	15	15	CD
cord-263862-zzys31e9	133	14	h	h	NN
cord-263862-zzys31e9	133	15	after	after	IN
cord-263862-zzys31e9	133	16	immunisation	immunisation	NN
cord-263862-zzys31e9	133	17	(	(	-LRB-
cord-263862-zzys31e9	133	18	Fig	Fig	NNP
cord-263862-zzys31e9	133	19	.	.	.
cord-263862-zzys31e9	133	20	2A	2a	CD
cord-263862-zzys31e9	133	21	)	)	-RRB-
cord-263862-zzys31e9	133	22	.	.	.
cord-263862-zzys31e9	134	1	The	the	DT
cord-263862-zzys31e9	134	2	IFN-	IFN-	NNP
cord-263862-zzys31e9	134	3	␥	␥	CD
cord-263862-zzys31e9	134	4	:mAb	:mab	CD
cord-263862-zzys31e9	134	5	complex	complex	NN
cord-263862-zzys31e9	134	6	continued	continue	VBD
cord-263862-zzys31e9	134	7	to	to	TO
cord-263862-zzys31e9	134	8	accumulate	accumulate	VB
cord-263862-zzys31e9	134	9	in	in	IN
cord-263862-zzys31e9	134	10	the	the	DT
cord-263862-zzys31e9	134	11	circulation	circulation	NN
cord-263862-zzys31e9	134	12	of	of	IN
cord-263862-zzys31e9	134	13	the	the	DT
cord-263862-zzys31e9	134	14	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	134	15	immunised	immunise	VBD
cord-263862-zzys31e9	134	16	mice	mouse	NNS
cord-263862-zzys31e9	134	17	up	up	IN
cord-263862-zzys31e9	134	18	to	to	IN
cord-263862-zzys31e9	134	19	72	72	CD
cord-263862-zzys31e9	134	20	h	h	NN
cord-263862-zzys31e9	134	21	post	post	NN
cord-263862-zzys31e9	134	22	-	-	NN
cord-263862-zzys31e9	134	23	immunisation	immunisation	JJ
cord-263862-zzys31e9	134	24	(	(	-LRB-
cord-263862-zzys31e9	134	25	Fig	Fig	NNP
cord-263862-zzys31e9	134	26	.	.	.
cord-263862-zzys31e9	134	27	2A	2a	CD
cord-263862-zzys31e9	134	28	)	)	-RRB-
cord-263862-zzys31e9	134	29	.	.	.
cord-263862-zzys31e9	135	1	The	the	DT
cord-263862-zzys31e9	135	2	anti	anti	JJ
cord-263862-zzys31e9	135	3	-	-	JJ
cord-263862-zzys31e9	135	4	IFN-	ifn-	JJ
cord-263862-zzys31e9	135	5	␥	␥	CD
cord-263862-zzys31e9	135	6	antibody	antibody	NN
cord-263862-zzys31e9	135	7	is	be	VBZ
cord-263862-zzys31e9	135	8	stable	stable	JJ
cord-263862-zzys31e9	135	9	for	for	IN
cord-263862-zzys31e9	135	10	up	up	IN
cord-263862-zzys31e9	135	11	to	to	TO
cord-263862-zzys31e9	135	12	72	72	CD
cord-263862-zzys31e9	135	13	h	h	NN
cord-263862-zzys31e9	135	14	in	in	IN
cord-263862-zzys31e9	135	15	vivo	vivo	NN
cord-263862-zzys31e9	135	16	.	.	.
cord-263862-zzys31e9	136	1	Using	use	VBG
cord-263862-zzys31e9	136	2	1/50th	1/50th	NNS
cord-263862-zzys31e9	136	3	of	of	IN
cord-263862-zzys31e9	136	4	the	the	DT
cord-263862-zzys31e9	136	5	human	human	JJ
cord-263862-zzys31e9	136	6	dose	dose	NN
cord-263862-zzys31e9	136	7	resulted	result	VBD
cord-263862-zzys31e9	136	8	in	in	IN
cord-263862-zzys31e9	136	9	less	less	RBR
cord-263862-zzys31e9	136	10	circulating	circulate	VBG
cord-263862-zzys31e9	136	11	IFN-	IFN-	NNP
cord-263862-zzys31e9	136	12	␥	␥	NNP
cord-263862-zzys31e9	136	13	than	than	IN
cord-263862-zzys31e9	136	14	1/10th	1/10th	CD
cord-263862-zzys31e9	136	15	of	of	IN
cord-263862-zzys31e9	136	16	the	the	DT
cord-263862-zzys31e9	136	17	human	human	JJ
cord-263862-zzys31e9	136	18	dose	dose	NN
cord-263862-zzys31e9	136	19	,	,	,
cord-263862-zzys31e9	136	20	illustrating	illustrate	VBG
cord-263862-zzys31e9	136	21	the	the	DT
cord-263862-zzys31e9	136	22	effect	effect	NN
cord-263862-zzys31e9	136	23	is	be	VBZ
cord-263862-zzys31e9	136	24	dose	dose	NN
cord-263862-zzys31e9	136	25	-	-	HYPH
cord-263862-zzys31e9	136	26	dependent	dependent	JJ
cord-263862-zzys31e9	136	27	(	(	-LRB-
cord-263862-zzys31e9	136	28	Fig	Fig	NNP
cord-263862-zzys31e9	136	29	.	.	.
cord-263862-zzys31e9	136	30	2A	2a	CD
cord-263862-zzys31e9	136	31	)	)	-RRB-
cord-263862-zzys31e9	136	32	.	.	.
cord-263862-zzys31e9	137	1	In	in	IN
cord-263862-zzys31e9	137	2	order	order	NN
cord-263862-zzys31e9	137	3	to	to	TO
cord-263862-zzys31e9	137	4	detect	detect	VB
cord-263862-zzys31e9	137	5	circulating	circulate	VBG
cord-263862-zzys31e9	137	6	IFN-	IFN-	NNP
cord-263862-zzys31e9	137	7	␣	␣	CD
cord-263862-zzys31e9	137	8	groups	group	NNS
cord-263862-zzys31e9	137	9	of	of	IN
cord-263862-zzys31e9	137	10	Balb	Balb	NNP
cord-263862-zzys31e9	137	11	/	/	SYM
cord-263862-zzys31e9	137	12	c	c	NN
cord-263862-zzys31e9	137	13	mice	mouse	NNS
cord-263862-zzys31e9	137	14	were	be	VBD
cord-263862-zzys31e9	137	15	immunised	immunise	VBN
cord-263862-zzys31e9	137	16	i.m	i.m	NNP
cord-263862-zzys31e9	137	17	.	.	.
cord-263862-zzys31e9	138	1	with	with	IN
cord-263862-zzys31e9	138	2	1/10th	1/10th	CD
cord-263862-zzys31e9	138	3	of	of	IN
cord-263862-zzys31e9	138	4	the	the	DT
cord-263862-zzys31e9	138	5	human	human	JJ
cord-263862-zzys31e9	138	6	dose	dose	NN
cord-263862-zzys31e9	138	7	of	of	IN
cord-263862-zzys31e9	138	8	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	138	9	and	and	CC
cord-263862-zzys31e9	138	10	then	then	RB
cord-263862-zzys31e9	138	11	bled	bleed	VBD
cord-263862-zzys31e9	138	12	at	at	IN
cord-263862-zzys31e9	138	13	various	various	JJ
cord-263862-zzys31e9	138	14	time	time	NN
cord-263862-zzys31e9	138	15	-	-	HYPH
cord-263862-zzys31e9	138	16	points	point	NNS
cord-263862-zzys31e9	138	17	,	,	,
cord-263862-zzys31e9	138	18	and	and	CC
cord-263862-zzys31e9	138	19	the	the	DT
cord-263862-zzys31e9	138	20	levels	level	NNS
cord-263862-zzys31e9	138	21	of	of	IN
cord-263862-zzys31e9	138	22	IFN-	IFN-	NNP
cord-263862-zzys31e9	138	23	␣	␣	NN
cord-263862-zzys31e9	138	24	in	in	IN
cord-263862-zzys31e9	138	25	the	the	DT
cord-263862-zzys31e9	138	26	serum	serum	NN
cord-263862-zzys31e9	138	27	were	be	VBD
cord-263862-zzys31e9	138	28	determined	determine	VBN
cord-263862-zzys31e9	138	29	by	by	IN
cord-263862-zzys31e9	138	30	ELISA	ELISA	NNP
cord-263862-zzys31e9	138	31	.	.	.
cord-263862-zzys31e9	139	1	A	a	DT
cord-263862-zzys31e9	139	2	low	low	JJ
cord-263862-zzys31e9	139	3	and	and	CC
cord-263862-zzys31e9	139	4	transient	transient	JJ
cord-263862-zzys31e9	139	5	amount	amount	NN
cord-263862-zzys31e9	139	6	of	of	IN
cord-263862-zzys31e9	139	7	IFN-	IFN-	NNP
cord-263862-zzys31e9	139	8	␣	␣	NN
cord-263862-zzys31e9	139	9	could	could	MD
cord-263862-zzys31e9	139	10	be	be	VB
cord-263862-zzys31e9	139	11	detected	detect	VBN
cord-263862-zzys31e9	139	12	at	at	IN
cord-263862-zzys31e9	139	13	2	2	CD
cord-263862-zzys31e9	139	14	h	h	NN
cord-263862-zzys31e9	139	15	in	in	IN
cord-263862-zzys31e9	139	16	the	the	DT
cord-263862-zzys31e9	139	17	serum	serum	NN
cord-263862-zzys31e9	139	18	of	of	IN
cord-263862-zzys31e9	139	19	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	139	20	immunised	immunise	VBD
cord-263862-zzys31e9	139	21	mice	mouse	NNS
cord-263862-zzys31e9	139	22	(	(	-LRB-
cord-263862-zzys31e9	139	23	Fig	Fig	NNP
cord-263862-zzys31e9	139	24	.	.	.
cord-263862-zzys31e9	139	25	2B	2b	CD
cord-263862-zzys31e9	139	26	)	)	-RRB-
cord-263862-zzys31e9	139	27	.	.	.
cord-263862-zzys31e9	140	1	In	in	IN
cord-263862-zzys31e9	140	2	summary	summary	NN
cord-263862-zzys31e9	140	3	,	,	,
cord-263862-zzys31e9	140	4	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	140	5	immunisation	immunisation	NN
cord-263862-zzys31e9	140	6	induces	induce	VBZ
cord-263862-zzys31e9	140	7	a	a	DT
cord-263862-zzys31e9	140	8	low	low	JJ
cord-263862-zzys31e9	140	9	amount	amount	NN
cord-263862-zzys31e9	140	10	of	of	IN
cord-263862-zzys31e9	140	11	IFN-	IFN-	NNP
cord-263862-zzys31e9	140	12	␣	␣	NN
cord-263862-zzys31e9	140	13	and	and	CC
cord-263862-zzys31e9	140	14	significant	significant	JJ
cord-263862-zzys31e9	140	15	amounts	amount	NNS
cord-263862-zzys31e9	140	16	of	of	IN
cord-263862-zzys31e9	140	17	IFN-	IFN-	NNP
cord-263862-zzys31e9	140	18	␥	␥	XX
cord-263862-zzys31e9	140	19	with	with	IN
cord-263862-zzys31e9	140	20	very	very	RB
cord-263862-zzys31e9	140	21	different	different	JJ
cord-263862-zzys31e9	140	22	kinetics	kinetic	NNS
cord-263862-zzys31e9	140	23	.	.	.
cord-263862-zzys31e9	141	1	IFN-	IFN-	NNP
cord-263862-zzys31e9	142	1	␣	␣	NNP
cord-263862-zzys31e9	142	2	being	be	VBG
cord-263862-zzys31e9	142	3	early	early	JJ
cord-263862-zzys31e9	142	4	and	and	CC
cord-263862-zzys31e9	142	5	transient	transient	JJ
cord-263862-zzys31e9	142	6	and	and	CC
cord-263862-zzys31e9	142	7	IFN-	IFN-	NNP
cord-263862-zzys31e9	142	8	␥	␥	NNP
cord-263862-zzys31e9	142	9	appearing	appear	VBG
cord-263862-zzys31e9	142	10	later	later	RB
cord-263862-zzys31e9	142	11	but	but	CC
cord-263862-zzys31e9	142	12	more	more	RBR
cord-263862-zzys31e9	142	13	sustained	sustained	JJ
cord-263862-zzys31e9	142	14	.	.	.
cord-263862-zzys31e9	143	1	However	however	RB
cord-263862-zzys31e9	143	2	,	,	,
cord-263862-zzys31e9	143	3	as	as	IN
cord-263862-zzys31e9	143	4	we	-PRON-	PRP
cord-263862-zzys31e9	143	5	used	use	VBD
cord-263862-zzys31e9	143	6	an	an	DT
cord-263862-zzys31e9	143	7	in	in	IN
cord-263862-zzys31e9	143	8	vivo	vivo	NN
cord-263862-zzys31e9	143	9	capture	capture	NN
cord-263862-zzys31e9	143	10	assay	assay	NN
cord-263862-zzys31e9	143	11	to	to	TO
cord-263862-zzys31e9	143	12	determine	determine	VB
cord-263862-zzys31e9	143	13	the	the	DT
cord-263862-zzys31e9	143	14	circulating	circulate	VBG
cord-263862-zzys31e9	143	15	amounts	amount	NNS
cord-263862-zzys31e9	143	16	of	of	IN
cord-263862-zzys31e9	143	17	IFN-	IFN-	NNP
cord-263862-zzys31e9	143	18	␥	␥	CD
cord-263862-zzys31e9	143	19	(	(	-LRB-
cord-263862-zzys31e9	143	20	stable	stable	JJ
cord-263862-zzys31e9	143	21	IFN-	IFN-	NNP
cord-263862-zzys31e9	143	22	␥	␥	CD
cord-263862-zzys31e9	143	23	:mAb	:mab	CD
cord-263862-zzys31e9	143	24	complex	complex	NN
cord-263862-zzys31e9	143	25	)	)	-RRB-
cord-263862-zzys31e9	143	26	and	and	CC
cord-263862-zzys31e9	143	27	a	a	DT
cord-263862-zzys31e9	143	28	straightforward	straightforward	JJ
cord-263862-zzys31e9	143	29	ELISA	ELISA	NNP
cord-263862-zzys31e9	143	30	approach	approach	NN
cord-263862-zzys31e9	143	31	to	to	TO
cord-263862-zzys31e9	143	32	detect	detect	VB
cord-263862-zzys31e9	143	33	the	the	DT
cord-263862-zzys31e9	143	34	relatively	relatively	RB
cord-263862-zzys31e9	143	35	labile	labile	JJ
cord-263862-zzys31e9	143	36	IFN-	IFN-	NNP
cord-263862-zzys31e9	143	37	␣	␣	NN
cord-263862-zzys31e9	143	38	,	,	,
cord-263862-zzys31e9	143	39	we	-PRON-	PRP
cord-263862-zzys31e9	143	40	can	can	MD
cord-263862-zzys31e9	143	41	not	not	RB
cord-263862-zzys31e9	143	42	draw	draw	VB
cord-263862-zzys31e9	143	43	any	any	DT
cord-263862-zzys31e9	143	44	conclusions	conclusion	NNS
cord-263862-zzys31e9	143	45	about	about	IN
cord-263862-zzys31e9	143	46	the	the	DT
cord-263862-zzys31e9	143	47	relative	relative	JJ
cord-263862-zzys31e9	143	48	importance	importance	NN
cord-263862-zzys31e9	143	49	of	of	IN
cord-263862-zzys31e9	143	50	the	the	DT
cord-263862-zzys31e9	143	51	two	two	CD
cord-263862-zzys31e9	143	52	cytokines	cytokine	NNS
cord-263862-zzys31e9	143	53	in	in	IN
cord-263862-zzys31e9	143	54	the	the	DT
cord-263862-zzys31e9	143	55	adjuvanticity	adjuvanticity	NN
cord-263862-zzys31e9	143	56	of	of	IN
cord-263862-zzys31e9	143	57	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	143	58	from	from	IN
cord-263862-zzys31e9	143	59	these	these	DT
cord-263862-zzys31e9	143	60	data	datum	NNS
cord-263862-zzys31e9	143	61	.	.	.
cord-263862-zzys31e9	144	1	At	at	IN
cord-263862-zzys31e9	144	2	various	various	JJ
cord-263862-zzys31e9	144	3	time	time	NN
cord-263862-zzys31e9	144	4	points	point	NNS
cord-263862-zzys31e9	144	5	serum	serum	NN
cord-263862-zzys31e9	144	6	samples	sample	NNS
cord-263862-zzys31e9	144	7	were	be	VBD
cord-263862-zzys31e9	144	8	prepared	prepare	VBN
cord-263862-zzys31e9	144	9	from	from	IN
cord-263862-zzys31e9	144	10	these	these	DT
cord-263862-zzys31e9	144	11	mice	mouse	NNS
cord-263862-zzys31e9	144	12	and	and	CC
cord-263862-zzys31e9	144	13	frozen	freeze	VBN
cord-263862-zzys31e9	144	14	at	at	IN
cord-263862-zzys31e9	144	15	−20	−20	NNP
cord-263862-zzys31e9	144	16	•	•	NNP
cord-263862-zzys31e9	144	17	C	C	NNP
cord-263862-zzys31e9	144	18	until	until	IN
cord-263862-zzys31e9	144	19	analysis	analysis	NN
cord-263862-zzys31e9	144	20	.	.	.
cord-263862-zzys31e9	145	1	Levels	level	NNS
cord-263862-zzys31e9	145	2	of	of	IN
cord-263862-zzys31e9	145	3	the	the	DT
cord-263862-zzys31e9	145	4	complex	complex	NN
cord-263862-zzys31e9	145	5	of	of	IN
cord-263862-zzys31e9	145	6	mAb	mAb	NNS
cord-263862-zzys31e9	145	7	+	+	CC
cord-263862-zzys31e9	145	8	IFN	IFN	NNP
cord-263862-zzys31e9	145	9	␥	␥	NNP
cord-263862-zzys31e9	145	10	were	be	VBD
cord-263862-zzys31e9	145	11	determined	determine	VBN
cord-263862-zzys31e9	145	12	by	by	IN
cord-263862-zzys31e9	145	13	an	an	DT
cord-263862-zzys31e9	145	14	ELISA	ELISA	NNP
cord-263862-zzys31e9	145	15	using	use	VBG
cord-263862-zzys31e9	145	16	a	a	DT
cord-263862-zzys31e9	145	17	standard	standard	JJ
cord-263862-zzys31e9	145	18	curve	curve	NN
cord-263862-zzys31e9	145	19	generated	generate	VBN
cord-263862-zzys31e9	145	20	using	use	VBG
cord-263862-zzys31e9	145	21	recombinant	recombinant	JJ
cord-263862-zzys31e9	145	22	IFN-	IFN-	NNP
cord-263862-zzys31e9	145	23	␥	␥	NNP
cord-263862-zzys31e9	145	24	that	that	WDT
cord-263862-zzys31e9	145	25	had	have	VBD
cord-263862-zzys31e9	145	26	been	be	VBN
cord-263862-zzys31e9	145	27	pre	pre	VBN
cord-263862-zzys31e9	145	28	-	-	VBN
cord-263862-zzys31e9	145	29	incubated	incubate	VBN
cord-263862-zzys31e9	145	30	with	with	IN
cord-263862-zzys31e9	145	31	biotinylated	biotinylated	JJ
cord-263862-zzys31e9	145	32	mAb	mAb	NNS
cord-263862-zzys31e9	145	33	.	.	.
cord-263862-zzys31e9	146	1	Results	result	NNS
cord-263862-zzys31e9	146	2	are	be	VBP
cord-263862-zzys31e9	146	3	expresses	express	VBZ
cord-263862-zzys31e9	146	4	as	as	IN
cord-263862-zzys31e9	146	5	mean	mean	JJ
cord-263862-zzys31e9	146	6	cytokine	cytokine	NN
cord-263862-zzys31e9	146	7	concentration	concentration	NN
cord-263862-zzys31e9	146	8	±	±	NNP
cord-263862-zzys31e9	146	9	standard	standard	JJ
cord-263862-zzys31e9	146	10	deviation	deviation	NN
cord-263862-zzys31e9	146	11	.	.	.
cord-263862-zzys31e9	147	1	*	*	NFP
cord-263862-zzys31e9	147	2	p	p	XX
cord-263862-zzys31e9	147	3	<	<	XX
cord-263862-zzys31e9	147	4	0.05	0.05	CD
cord-263862-zzys31e9	147	5	,	,	,
cord-263862-zzys31e9	148	1	*	*	NFP
cord-263862-zzys31e9	148	2	*	*	NFP
cord-263862-zzys31e9	148	3	*	*	NFP
cord-263862-zzys31e9	148	4	p	p	XX
cord-263862-zzys31e9	148	5	<	<	XX
cord-263862-zzys31e9	148	6	0.001	0.001	CD
cord-263862-zzys31e9	148	7	and	and	CC
cord-263862-zzys31e9	148	8	ns	ns	NNP
cord-263862-zzys31e9	148	9	=	=	NFP
cord-263862-zzys31e9	148	10	not	not	RB
cord-263862-zzys31e9	148	11	significant	significant	JJ
cord-263862-zzys31e9	148	12	.	.	.
cord-263862-zzys31e9	149	1	(	(	-LRB-
cord-263862-zzys31e9	149	2	B	b	NN
cord-263862-zzys31e9	149	3	)	)	-RRB-
cord-263862-zzys31e9	150	1	In	in	IN
cord-263862-zzys31e9	150	2	a	a	DT
cord-263862-zzys31e9	150	3	separate	separate	JJ
cord-263862-zzys31e9	150	4	experiment	experiment	NN
cord-263862-zzys31e9	150	5	groups	group	NNS
cord-263862-zzys31e9	150	6	of	of	IN
cord-263862-zzys31e9	150	7	Balb	Balb	NNP
cord-263862-zzys31e9	150	8	/	/	SYM
cord-263862-zzys31e9	150	9	c	c	NN
cord-263862-zzys31e9	150	10	mice	mouse	NNS
cord-263862-zzys31e9	150	11	(	(	-LRB-
cord-263862-zzys31e9	150	12	5	5	CD
cord-263862-zzys31e9	150	13	per	per	IN
cord-263862-zzys31e9	150	14	group	group	NN
cord-263862-zzys31e9	150	15	)	)	-RRB-
cord-263862-zzys31e9	150	16	were	be	VBD
cord-263862-zzys31e9	150	17	immunised	immunise	VBN
cord-263862-zzys31e9	150	18	with	with	IN
cord-263862-zzys31e9	150	19	Placebo	Placebo	NNP
cord-263862-zzys31e9	150	20	or	or	CC
cord-263862-zzys31e9	150	21	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	150	22	(	(	-LRB-
cord-263862-zzys31e9	150	23	1/10	1/10	CD
cord-263862-zzys31e9	150	24	human	human	JJ
cord-263862-zzys31e9	150	25	dose	dose	NN
cord-263862-zzys31e9	150	26	)	)	-RRB-
cord-263862-zzys31e9	150	27	at	at	IN
cord-263862-zzys31e9	150	28	time	time	NN
cord-263862-zzys31e9	150	29	0	0	CD
cord-263862-zzys31e9	150	30	.	.	.
cord-263862-zzys31e9	151	1	Serum	serum	NN
cord-263862-zzys31e9	151	2	samples	sample	NNS
cord-263862-zzys31e9	151	3	were	be	VBD
cord-263862-zzys31e9	151	4	removed	remove	VBN
cord-263862-zzys31e9	151	5	at	at	IN
cord-263862-zzys31e9	151	6	various	various	JJ
cord-263862-zzys31e9	151	7	time	time	NN
cord-263862-zzys31e9	151	8	-	-	HYPH
cord-263862-zzys31e9	151	9	points	point	NNS
cord-263862-zzys31e9	151	10	and	and	CC
cord-263862-zzys31e9	151	11	frozen	freeze	VBN
cord-263862-zzys31e9	151	12	at	at	IN
cord-263862-zzys31e9	151	13	−20	−20	NNP
cord-263862-zzys31e9	151	14	•	•	NNP
cord-263862-zzys31e9	151	15	C	C	NNP
cord-263862-zzys31e9	151	16	until	until	IN
cord-263862-zzys31e9	151	17	analysis	analysis	NN
cord-263862-zzys31e9	151	18	.	.	.
cord-263862-zzys31e9	152	1	Levels	level	NNS
cord-263862-zzys31e9	152	2	of	of	IN
cord-263862-zzys31e9	152	3	serum	serum	NN
cord-263862-zzys31e9	153	1	IFN-	IFN-	NNP
cord-263862-zzys31e9	153	2	␣	␣	NNP
cord-263862-zzys31e9	153	3	were	be	VBD
cord-263862-zzys31e9	153	4	determined	determine	VBN
cord-263862-zzys31e9	153	5	by	by	IN
cord-263862-zzys31e9	153	6	ELISA	ELISA	NNP
cord-263862-zzys31e9	153	7	in	in	IN
cord-263862-zzys31e9	153	8	triplicate	triplicate	NN
cord-263862-zzys31e9	153	9	on	on	IN
cord-263862-zzys31e9	153	10	serum	serum	NN
cord-263862-zzys31e9	153	11	pools	pool	NNS
cord-263862-zzys31e9	153	12	from	from	IN
cord-263862-zzys31e9	153	13	each	each	DT
cord-263862-zzys31e9	153	14	group	group	NN
cord-263862-zzys31e9	153	15	.	.	.
cord-263862-zzys31e9	154	1	Results	result	NNS
cord-263862-zzys31e9	154	2	are	be	VBP
cord-263862-zzys31e9	154	3	expressed	express	VBN
cord-263862-zzys31e9	154	4	as	as	IN
cord-263862-zzys31e9	154	5	the	the	DT
cord-263862-zzys31e9	154	6	mean	mean	JJ
cord-263862-zzys31e9	154	7	cytokine	cytokine	NN
cord-263862-zzys31e9	154	8	concentration	concentration	NN
cord-263862-zzys31e9	154	9	±	±	NNP
cord-263862-zzys31e9	154	10	standard	standard	JJ
cord-263862-zzys31e9	154	11	error	error	NN
cord-263862-zzys31e9	154	12	.	.	.
cord-263862-zzys31e9	155	1	As	as	IN
cord-263862-zzys31e9	155	2	we	-PRON-	PRP
cord-263862-zzys31e9	155	3	demonstrated	demonstrate	VBD
cord-263862-zzys31e9	155	4	that	that	IN
cord-263862-zzys31e9	155	5	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	155	6	could	could	MD
cord-263862-zzys31e9	155	7	induce	induce	VB
cord-263862-zzys31e9	155	8	both	both	DT
cord-263862-zzys31e9	155	9	innate	innate	JJ
cord-263862-zzys31e9	155	10	IFN-	IFN-	NNP
cord-263862-zzys31e9	156	1	␣	␣	NNP
cord-263862-zzys31e9	157	1	and	and	CC
cord-263862-zzys31e9	157	2	IFN-	IFN-	NNP
cord-263862-zzys31e9	157	3	␥	␥	NNP
cord-263862-zzys31e9	157	4	(	(	-LRB-
cord-263862-zzys31e9	157	5	albeit	albeit	IN
cord-263862-zzys31e9	157	6	in	in	IN
cord-263862-zzys31e9	157	7	different	different	JJ
cord-263862-zzys31e9	157	8	amounts	amount	NNS
cord-263862-zzys31e9	157	9	and	and	CC
cord-263862-zzys31e9	157	10	with	with	IN
cord-263862-zzys31e9	157	11	varied	varied	JJ
cord-263862-zzys31e9	157	12	kinetics	kinetic	NNS
cord-263862-zzys31e9	157	13	)	)	-RRB-
cord-263862-zzys31e9	157	14	,	,	,
cord-263862-zzys31e9	157	15	we	-PRON-	PRP
cord-263862-zzys31e9	157	16	wished	wish	VBD
cord-263862-zzys31e9	157	17	to	to	TO
cord-263862-zzys31e9	157	18	address	address	VB
cord-263862-zzys31e9	157	19	the	the	DT
cord-263862-zzys31e9	157	20	question	question	NN
cord-263862-zzys31e9	157	21	whether	whether	IN
cord-263862-zzys31e9	157	22	the	the	DT
cord-263862-zzys31e9	157	23	induction	induction	NN
cord-263862-zzys31e9	157	24	of	of	IN
cord-263862-zzys31e9	157	25	one	one	CD
cord-263862-zzys31e9	157	26	or	or	CC
cord-263862-zzys31e9	157	27	both	both	DT
cord-263862-zzys31e9	157	28	of	of	IN
cord-263862-zzys31e9	157	29	these	these	DT
cord-263862-zzys31e9	157	30	cytokines	cytokine	NNS
cord-263862-zzys31e9	157	31	were	be	VBD
cord-263862-zzys31e9	157	32	crucial	crucial	JJ
cord-263862-zzys31e9	157	33	for	for	IN
cord-263862-zzys31e9	157	34	the	the	DT
cord-263862-zzys31e9	157	35	adjuvant	adjuvant	JJ
cord-263862-zzys31e9	157	36	activity	activity	NN
cord-263862-zzys31e9	157	37	of	of	IN
cord-263862-zzys31e9	157	38	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	157	39	.	.	.
cord-263862-zzys31e9	158	1	In	in	IN
cord-263862-zzys31e9	158	2	order	order	NN
cord-263862-zzys31e9	158	3	to	to	TO
cord-263862-zzys31e9	158	4	do	do	VB
cord-263862-zzys31e9	158	5	this	this	DT
cord-263862-zzys31e9	158	6	we	-PRON-	PRP
cord-263862-zzys31e9	158	7	immunised	immunise	VBD
cord-263862-zzys31e9	158	8	groups	group	NNS
cord-263862-zzys31e9	158	9	of	of	IN
cord-263862-zzys31e9	158	10	wild	wild	JJ
cord-263862-zzys31e9	158	11	type	type	NN
cord-263862-zzys31e9	158	12	(	(	-LRB-
cord-263862-zzys31e9	158	13	129	129	CD
cord-263862-zzys31e9	158	14	/	/	SYM
cord-263862-zzys31e9	158	15	Sv	Sv	NNP
cord-263862-zzys31e9	158	16	)	)	-RRB-
cord-263862-zzys31e9	158	17	,	,	,
cord-263862-zzys31e9	158	18	IFN-	IFN-	NNP
cord-263862-zzys31e9	158	19	␣	␣	NN
cord-263862-zzys31e9	158	20	R	R	NNP
cord-263862-zzys31e9	158	21	−/−	−/−	NNP
cord-263862-zzys31e9	158	22	and	and	CC
cord-263862-zzys31e9	158	23	IFN-	IFN-	NNP
cord-263862-zzys31e9	159	1	␥	␥	NNP
cord-263862-zzys31e9	159	2	R	R	NNP
cord-263862-zzys31e9	159	3	−/−	−/−	NNP
cord-263862-zzys31e9	159	4	mice	mouse	NNS
cord-263862-zzys31e9	159	5	with	with	IN
cord-263862-zzys31e9	159	6	either	either	DT
cord-263862-zzys31e9	159	7	gB	gB	NNP
cord-263862-zzys31e9	159	8	and	and	CC
cord-263862-zzys31e9	159	9	Placebo	Placebo	NNP
cord-263862-zzys31e9	159	10	or	or	CC
cord-263862-zzys31e9	159	11	gB	gB	NNP
cord-263862-zzys31e9	159	12	and	and	CC
cord-263862-zzys31e9	159	13	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	159	14	and	and	CC
cord-263862-zzys31e9	159	15	then	then	RB
cord-263862-zzys31e9	159	16	evaluated	evaluate	VBD
cord-263862-zzys31e9	159	17	the	the	DT
cord-263862-zzys31e9	159	18	gB	gB	NNP
cord-263862-zzys31e9	159	19	specific	specific	JJ
cord-263862-zzys31e9	159	20	immune	immune	JJ
cord-263862-zzys31e9	159	21	responses	response	NNS
cord-263862-zzys31e9	159	22	.	.	.
cord-263862-zzys31e9	160	1	This	this	DT
cord-263862-zzys31e9	160	2	approach	approach	NN
cord-263862-zzys31e9	160	3	enabled	enable	VBD
cord-263862-zzys31e9	160	4	us	-PRON-	PRP
cord-263862-zzys31e9	160	5	to	to	TO
cord-263862-zzys31e9	160	6	observe	observe	VB
cord-263862-zzys31e9	160	7	if	if	IN
cord-263862-zzys31e9	160	8	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	160	9	maintained	maintain	VBD
cord-263862-zzys31e9	160	10	its	-PRON-	PRP$
cord-263862-zzys31e9	160	11	adjuvant	adjuvant	NN
cord-263862-zzys31e9	160	12	properties	property	NNS
cord-263862-zzys31e9	160	13	in	in	IN
cord-263862-zzys31e9	160	14	the	the	DT
cord-263862-zzys31e9	160	15	absence	absence	NN
cord-263862-zzys31e9	160	16	of	of	IN
cord-263862-zzys31e9	160	17	bioactive	bioactive	JJ
cord-263862-zzys31e9	160	18	IFN-	IFN-	NNP
cord-263862-zzys31e9	160	19	␣	␣	NNP
cord-263862-zzys31e9	160	20	or	or	CC
cord-263862-zzys31e9	160	21	IFN-	IFN-	NNP
cord-263862-zzys31e9	160	22	␥	␥	XX
cord-263862-zzys31e9	160	23	.	.	.
cord-263862-zzys31e9	161	1	Anti	Anti	NNP
cord-263862-zzys31e9	161	2	-	-	JJ
cord-263862-zzys31e9	161	3	gB	gb	JJ
cord-263862-zzys31e9	161	4	specific	specific	JJ
cord-263862-zzys31e9	161	5	IgG	igg	NN
cord-263862-zzys31e9	161	6	levels	level	NNS
cord-263862-zzys31e9	161	7	were	be	VBD
cord-263862-zzys31e9	161	8	similar	similar	JJ
cord-263862-zzys31e9	161	9	in	in	IN
cord-263862-zzys31e9	161	10	all	all	DT
cord-263862-zzys31e9	161	11	groups	group	NNS
cord-263862-zzys31e9	161	12	of	of	IN
cord-263862-zzys31e9	161	13	mice	mouse	NNS
cord-263862-zzys31e9	161	14	irrespective	irrespective	RB
cord-263862-zzys31e9	161	15	of	of	IN
cord-263862-zzys31e9	161	16	mouse	mouse	NN
cord-263862-zzys31e9	161	17	genotype	genotype	NN
cord-263862-zzys31e9	161	18	or	or	CC
cord-263862-zzys31e9	161	19	vaccine	vaccine	NN
cord-263862-zzys31e9	161	20	(	(	-LRB-
cord-263862-zzys31e9	161	21	Fig	Fig	NNP
cord-263862-zzys31e9	161	22	.	.	.
cord-263862-zzys31e9	161	23	3A	3A	NNP
cord-263862-zzys31e9	161	24	)	)	-RRB-
cord-263862-zzys31e9	161	25	.	.	.
cord-263862-zzys31e9	162	1	Anti	Anti	NNP
cord-263862-zzys31e9	162	2	-	-	JJ
cord-263862-zzys31e9	162	3	gB	gb	JJ
cord-263862-zzys31e9	162	4	specific	specific	JJ
cord-263862-zzys31e9	162	5	IgG1	igg1	CD
cord-263862-zzys31e9	162	6	levels	level	NNS
cord-263862-zzys31e9	162	7	were	be	VBD
cord-263862-zzys31e9	162	8	marginally	marginally	RB
cord-263862-zzys31e9	162	9	reduced	reduce	VBN
cord-263862-zzys31e9	162	10	in	in	IN
cord-263862-zzys31e9	162	11	the	the	DT
cord-263862-zzys31e9	162	12	groups	group	NNS
cord-263862-zzys31e9	162	13	that	that	WDT
cord-263862-zzys31e9	162	14	received	receive	VBD
cord-263862-zzys31e9	162	15	gB	gB	NNP
cord-263862-zzys31e9	162	16	and	and	CC
cord-263862-zzys31e9	162	17	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	162	18	compared	compare	VBN
cord-263862-zzys31e9	162	19	.	.	.
cord-263862-zzys31e9	163	1	The	the	DT
cord-263862-zzys31e9	163	2	animals	animal	NNS
cord-263862-zzys31e9	163	3	were	be	VBD
cord-263862-zzys31e9	163	4	boosted	boost	VBN
cord-263862-zzys31e9	163	5	at	at	IN
cord-263862-zzys31e9	163	6	day	day	NN
cord-263862-zzys31e9	163	7	21	21	CD
cord-263862-zzys31e9	163	8	and	and	CC
cord-263862-zzys31e9	163	9	serum	serum	NN
cord-263862-zzys31e9	163	10	samples	sample	NNS
cord-263862-zzys31e9	163	11	taken	take	VBN
cord-263862-zzys31e9	163	12	at	at	IN
cord-263862-zzys31e9	163	13	day	day	NN
cord-263862-zzys31e9	163	14	35	35	CD
cord-263862-zzys31e9	163	15	.	.	.
cord-263862-zzys31e9	164	1	Anti	Anti	NNP
cord-263862-zzys31e9	164	2	-	-	JJ
cord-263862-zzys31e9	164	3	gB	gb	JJ
cord-263862-zzys31e9	164	4	specific	specific	JJ
cord-263862-zzys31e9	164	5	IgG	igg	NN
cord-263862-zzys31e9	164	6	(	(	-LRB-
cord-263862-zzys31e9	164	7	A	A	NNP
cord-263862-zzys31e9	164	8	)	)	-RRB-
cord-263862-zzys31e9	164	9	,	,	,
cord-263862-zzys31e9	164	10	IgG1	igg1	FW
cord-263862-zzys31e9	164	11	(	(	-LRB-
cord-263862-zzys31e9	164	12	B	b	NN
cord-263862-zzys31e9	164	13	)	)	-RRB-
cord-263862-zzys31e9	164	14	and	and	CC
cord-263862-zzys31e9	164	15	IgG2a	IgG2a	NNP
cord-263862-zzys31e9	164	16	(	(	-LRB-
cord-263862-zzys31e9	164	17	C	C	NNP
cord-263862-zzys31e9	164	18	)	)	-RRB-
cord-263862-zzys31e9	164	19	titres	titre	NNS
cord-263862-zzys31e9	164	20	were	be	VBD
cord-263862-zzys31e9	164	21	determined	determine	VBN
cord-263862-zzys31e9	164	22	by	by	IN
cord-263862-zzys31e9	164	23	ELISA	ELISA	NNP
cord-263862-zzys31e9	164	24	.	.	.
cord-263862-zzys31e9	165	1	Results	result	NNS
cord-263862-zzys31e9	165	2	represented	represent	VBN
cord-263862-zzys31e9	165	3	are	be	VBP
cord-263862-zzys31e9	165	4	the	the	DT
cord-263862-zzys31e9	165	5	mean	mean	JJ
cord-263862-zzys31e9	165	6	±	±	NNP
cord-263862-zzys31e9	165	7	standard	standard	JJ
cord-263862-zzys31e9	165	8	deviation	deviation	NN
cord-263862-zzys31e9	165	9	of	of	IN
cord-263862-zzys31e9	165	10	5	5	CD
cord-263862-zzys31e9	165	11	mice	mouse	NNS
cord-263862-zzys31e9	165	12	per	per	IN
cord-263862-zzys31e9	165	13	group	group	NN
cord-263862-zzys31e9	165	14	,	,	,
cord-263862-zzys31e9	165	15	*	*	NFP
cord-263862-zzys31e9	165	16	*	*	NFP
cord-263862-zzys31e9	165	17	*	*	NFP
cord-263862-zzys31e9	165	18	p	p	XX
cord-263862-zzys31e9	165	19	<	<	XX
cord-263862-zzys31e9	165	20	0.001	0.001	CD
cord-263862-zzys31e9	165	21	and	and	CC
cord-263862-zzys31e9	165	22	ns	ns	NNP
cord-263862-zzys31e9	165	23	=	=	NFP
cord-263862-zzys31e9	165	24	not	not	RB
cord-263862-zzys31e9	165	25	significant	significant	JJ
cord-263862-zzys31e9	165	26	.	.	.
cord-263862-zzys31e9	166	1	The	the	DT
cord-263862-zzys31e9	166	2	anti	anti	JJ
cord-263862-zzys31e9	166	3	-	-	JJ
cord-263862-zzys31e9	166	4	gB	gb	JJ
cord-263862-zzys31e9	166	5	specific	specific	JJ
cord-263862-zzys31e9	166	6	IgG1	igg1	NN
cord-263862-zzys31e9	166	7	:	:	:
cord-263862-zzys31e9	167	1	IgG2a	igg2a	JJ
cord-263862-zzys31e9	167	2	ratio	ratio	NN
cord-263862-zzys31e9	167	3	was	be	VBD
cord-263862-zzys31e9	167	4	determined	determine	VBN
cord-263862-zzys31e9	167	5	(	(	-LRB-
cord-263862-zzys31e9	167	6	D	D	NNP
cord-263862-zzys31e9	167	7	)	)	-RRB-
cord-263862-zzys31e9	167	8	.	.	.
cord-263862-zzys31e9	168	1	A	a	DT
cord-263862-zzys31e9	168	2	value	value	NN
cord-263862-zzys31e9	168	3	of	of	IN
cord-263862-zzys31e9	168	4	1	1	CD
cord-263862-zzys31e9	168	5	indicates	indicate	VBZ
cord-263862-zzys31e9	168	6	that	that	IN
cord-263862-zzys31e9	168	7	equal	equal	JJ
cord-263862-zzys31e9	168	8	amounts	amount	NNS
cord-263862-zzys31e9	168	9	of	of	IN
cord-263862-zzys31e9	168	10	antigen	antigen	NN
cord-263862-zzys31e9	168	11	-	-	HYPH
cord-263862-zzys31e9	168	12	specific	specific	JJ
cord-263862-zzys31e9	168	13	IgG1	igg1	NN
cord-263862-zzys31e9	168	14	and	and	CC
cord-263862-zzys31e9	168	15	IgG2a	IgG2a	NNP
cord-263862-zzys31e9	168	16	was	be	VBD
cord-263862-zzys31e9	168	17	produced	produce	VBN
cord-263862-zzys31e9	168	18	,	,	,
cord-263862-zzys31e9	168	19	values	value	NNS
cord-263862-zzys31e9	168	20	greater	great	JJR
cord-263862-zzys31e9	168	21	than	than	IN
cord-263862-zzys31e9	168	22	1	1	CD
cord-263862-zzys31e9	168	23	indicate	indicate	VBP
cord-263862-zzys31e9	168	24	that	that	IN
cord-263862-zzys31e9	168	25	more	more	JJR
cord-263862-zzys31e9	168	26	anti	anti	JJ
cord-263862-zzys31e9	168	27	-	-	JJ
cord-263862-zzys31e9	168	28	specific	specific	JJ
cord-263862-zzys31e9	168	29	IgG1	igg1	NN
cord-263862-zzys31e9	168	30	than	than	IN
cord-263862-zzys31e9	168	31	IgG2a	IgG2a	NNP
cord-263862-zzys31e9	168	32	,	,	,
cord-263862-zzys31e9	168	33	while	while	IN
cord-263862-zzys31e9	168	34	values	value	NNS
cord-263862-zzys31e9	168	35	less	less	JJR
cord-263862-zzys31e9	168	36	than	than	IN
cord-263862-zzys31e9	168	37	one	one	CD
cord-263862-zzys31e9	168	38	signify	signify	RB
cord-263862-zzys31e9	168	39	that	that	WDT
cord-263862-zzys31e9	168	40	more	more	RBR
cord-263862-zzys31e9	168	41	IgG2a	igg2a	JJ
cord-263862-zzys31e9	168	42	than	than	IN
cord-263862-zzys31e9	168	43	IgG1	IgG1	NNP
cord-263862-zzys31e9	168	44	.	.	.
cord-263862-zzys31e9	169	1	with	with	IN
cord-263862-zzys31e9	169	2	those	those	DT
cord-263862-zzys31e9	169	3	that	that	WDT
cord-263862-zzys31e9	169	4	received	receive	VBD
cord-263862-zzys31e9	169	5	gB	gB	NNP
cord-263862-zzys31e9	169	6	and	and	CC
cord-263862-zzys31e9	169	7	Placebo	Placebo	NNP
cord-263862-zzys31e9	169	8	in	in	IN
cord-263862-zzys31e9	169	9	each	each	DT
cord-263862-zzys31e9	169	10	of	of	IN
cord-263862-zzys31e9	169	11	the	the	DT
cord-263862-zzys31e9	169	12	genotypes	genotype	NNS
cord-263862-zzys31e9	169	13	(	(	-LRB-
cord-263862-zzys31e9	169	14	Fig	fig	NN
cord-263862-zzys31e9	169	15	.	.	.
cord-263862-zzys31e9	169	16	3B	3B	NNP
cord-263862-zzys31e9	169	17	)	)	-RRB-
cord-263862-zzys31e9	169	18	.	.	.
cord-263862-zzys31e9	170	1	However	however	RB
cord-263862-zzys31e9	170	2	,	,	,
cord-263862-zzys31e9	170	3	a	a	DT
cord-263862-zzys31e9	170	4	clear	clear	JJ
cord-263862-zzys31e9	170	5	augmentation	augmentation	NN
cord-263862-zzys31e9	170	6	of	of	IN
cord-263862-zzys31e9	170	7	gB	gB	NNP
cord-263862-zzys31e9	171	1	specific	specific	JJ
cord-263862-zzys31e9	171	2	IgG2a	IgG2a	NNP
cord-263862-zzys31e9	171	3	was	be	VBD
cord-263862-zzys31e9	171	4	observed	observe	VBN
cord-263862-zzys31e9	171	5	in	in	IN
cord-263862-zzys31e9	171	6	both	both	DT
cord-263862-zzys31e9	171	7	129	129	CD
cord-263862-zzys31e9	171	8	/	/	SYM
cord-263862-zzys31e9	171	9	Sv	Sv	NNP
cord-263862-zzys31e9	171	10	and	and	CC
cord-263862-zzys31e9	171	11	IFN-	IFN-	NNP
cord-263862-zzys31e9	172	1	␣	␣	NNP
cord-263862-zzys31e9	172	2	R	R	NNP
cord-263862-zzys31e9	172	3	−/−	−/−	NNP
cord-263862-zzys31e9	172	4	mice	mouse	NNS
cord-263862-zzys31e9	172	5	that	that	WDT
cord-263862-zzys31e9	172	6	received	receive	VBD
cord-263862-zzys31e9	172	7	gB	gB	NNP
cord-263862-zzys31e9	172	8	and	and	CC
cord-263862-zzys31e9	172	9	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	173	1	compared	compare	VBN
cord-263862-zzys31e9	173	2	to	to	IN
cord-263862-zzys31e9	173	3	gB	gB	NNP
cord-263862-zzys31e9	173	4	and	and	CC
cord-263862-zzys31e9	173	5	Placebo	Placebo	NNP
cord-263862-zzys31e9	173	6	.	.	.
cord-263862-zzys31e9	174	1	In	in	IN
cord-263862-zzys31e9	174	2	contrast	contrast	NN
cord-263862-zzys31e9	174	3	,	,	,
cord-263862-zzys31e9	174	4	no	no	DT
cord-263862-zzys31e9	174	5	significant	significant	JJ
cord-263862-zzys31e9	174	6	increase	increase	NN
cord-263862-zzys31e9	174	7	in	in	IN
cord-263862-zzys31e9	174	8	anti	anti	JJ
cord-263862-zzys31e9	174	9	-	-	JJ
cord-263862-zzys31e9	174	10	gB	gb	JJ
cord-263862-zzys31e9	174	11	IgG2a	IgG2a	NNP
cord-263862-zzys31e9	174	12	was	be	VBD
cord-263862-zzys31e9	174	13	observed	observe	VBN
cord-263862-zzys31e9	174	14	in	in	IN
cord-263862-zzys31e9	175	1	IFN-	IFN-	NNP
cord-263862-zzys31e9	175	2	␥	␥	NNP
cord-263862-zzys31e9	175	3	R	r	NN
cord-263862-zzys31e9	175	4	−/−	−/−	NNP
cord-263862-zzys31e9	175	5	mice	mouse	NNS
cord-263862-zzys31e9	175	6	upon	upon	IN
cord-263862-zzys31e9	175	7	the	the	DT
cord-263862-zzys31e9	175	8	addition	addition	NN
cord-263862-zzys31e9	175	9	of	of	IN
cord-263862-zzys31e9	175	10	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	175	11	to	to	IN
cord-263862-zzys31e9	175	12	the	the	DT
cord-263862-zzys31e9	175	13	protein	protein	NN
cord-263862-zzys31e9	175	14	antigen	antigen	NN
cord-263862-zzys31e9	175	15	(	(	-LRB-
cord-263862-zzys31e9	175	16	Fig	Fig	NNP
cord-263862-zzys31e9	175	17	.	.	.
cord-263862-zzys31e9	175	18	3C	3C	NNP
cord-263862-zzys31e9	175	19	)	)	-RRB-
cord-263862-zzys31e9	175	20	.	.	.
cord-263862-zzys31e9	176	1	These	these	DT
cord-263862-zzys31e9	176	2	data	datum	NNS
cord-263862-zzys31e9	176	3	indicates	indicate	VBZ
cord-263862-zzys31e9	176	4	that	that	IN
cord-263862-zzys31e9	176	5	although	although	IN
cord-263862-zzys31e9	176	6	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	176	7	induces	induce	VBZ
cord-263862-zzys31e9	176	8	both	both	DT
cord-263862-zzys31e9	176	9	innate	innate	JJ
cord-263862-zzys31e9	176	10	IFN-	IFN-	NNP
cord-263862-zzys31e9	177	1	␣	␣	NNP
cord-263862-zzys31e9	177	2	and	and	CC
cord-263862-zzys31e9	177	3	IFN-	IFN-	NNP
cord-263862-zzys31e9	177	4	␥	␥	CD
cord-263862-zzys31e9	177	5	production	production	NN
cord-263862-zzys31e9	177	6	in	in	IN
cord-263862-zzys31e9	177	7	vivo	vivo	NN
cord-263862-zzys31e9	177	8	,	,	,
cord-263862-zzys31e9	178	1	IFN-	IFN-	NNP
cord-263862-zzys31e9	178	2	␣	␣	NNP
cord-263862-zzys31e9	178	3	is	be	VBZ
cord-263862-zzys31e9	178	4	dispensable	dispensable	JJ
cord-263862-zzys31e9	178	5	for	for	IN
cord-263862-zzys31e9	178	6	the	the	DT
cord-263862-zzys31e9	178	7	augmentation	augmentation	NN
cord-263862-zzys31e9	178	8	of	of	IN
cord-263862-zzys31e9	178	9	specific	specific	JJ
cord-263862-zzys31e9	178	10	IgG2a	IgG2a	NNP
cord-263862-zzys31e9	178	11	to	to	TO
cord-263862-zzys31e9	178	12	co	co	VB
cord-263862-zzys31e9	178	13	-	-	JJ
cord-263862-zzys31e9	178	14	injected	inject	VBN
cord-263862-zzys31e9	178	15	antigen	antigen	NN
cord-263862-zzys31e9	178	16	.	.	.
cord-263862-zzys31e9	179	1	NK	NK	NNP
cord-263862-zzys31e9	179	2	cells	cell	NNS
cord-263862-zzys31e9	179	3	are	be	VBP
cord-263862-zzys31e9	179	4	a	a	DT
cord-263862-zzys31e9	179	5	major	major	JJ
cord-263862-zzys31e9	179	6	cellular	cellular	JJ
cord-263862-zzys31e9	179	7	source	source	NN
cord-263862-zzys31e9	179	8	of	of	IN
cord-263862-zzys31e9	179	9	the	the	DT
cord-263862-zzys31e9	179	10	IFN-	IFN-	NNP
cord-263862-zzys31e9	179	11	␥	␥	NNPS
cord-263862-zzys31e9	179	12	produced	produce	VBN
cord-263862-zzys31e9	179	13	during	during	IN
cord-263862-zzys31e9	179	14	the	the	DT
cord-263862-zzys31e9	179	15	first	first	JJ
cord-263862-zzys31e9	179	16	phase	phase	NN
cord-263862-zzys31e9	179	17	of	of	IN
cord-263862-zzys31e9	179	18	the	the	DT
cord-263862-zzys31e9	179	19	immune	immune	JJ
cord-263862-zzys31e9	179	20	response	response	NN
cord-263862-zzys31e9	179	21	to	to	IN
cord-263862-zzys31e9	179	22	infection	infection	NN
cord-263862-zzys31e9	179	23	[	[	-LRB-
cord-263862-zzys31e9	179	24	14	14	CD
cord-263862-zzys31e9	179	25	]	]	-RRB-
cord-263862-zzys31e9	179	26	.	.	.
cord-263862-zzys31e9	180	1	In	in	IN
cord-263862-zzys31e9	180	2	order	order	NN
cord-263862-zzys31e9	180	3	to	to	TO
cord-263862-zzys31e9	180	4	determine	determine	VB
cord-263862-zzys31e9	180	5	their	-PRON-	PRP$
cord-263862-zzys31e9	180	6	role	role	NN
cord-263862-zzys31e9	180	7	in	in	IN
cord-263862-zzys31e9	180	8	the	the	DT
cord-263862-zzys31e9	180	9	innate	innate	JJ
cord-263862-zzys31e9	180	10	immune	immune	JJ
cord-263862-zzys31e9	180	11	response	response	NN
cord-263862-zzys31e9	180	12	to	to	IN
cord-263862-zzys31e9	180	13	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	180	14	we	-PRON-	PRP
cord-263862-zzys31e9	180	15	depleted	deplete	VBD
cord-263862-zzys31e9	180	16	NK	NK	NNP
cord-263862-zzys31e9	180	17	cells	cell	NNS
cord-263862-zzys31e9	180	18	from	from	IN
cord-263862-zzys31e9	180	19	Balb	Balb	NNP
cord-263862-zzys31e9	180	20	/	/	SYM
cord-263862-zzys31e9	180	21	c	c	NN
cord-263862-zzys31e9	180	22	mice	mouse	NNS
cord-263862-zzys31e9	180	23	and	and	CC
cord-263862-zzys31e9	180	24	then	then	RB
cord-263862-zzys31e9	180	25	measured	measure	VBD
cord-263862-zzys31e9	180	26	the	the	DT
cord-263862-zzys31e9	180	27	ability	ability	NN
cord-263862-zzys31e9	180	28	of	of	IN
cord-263862-zzys31e9	180	29	these	these	DT
cord-263862-zzys31e9	180	30	mice	mouse	NNS
cord-263862-zzys31e9	180	31	to	to	TO
cord-263862-zzys31e9	180	32	produce	produce	VB
cord-263862-zzys31e9	180	33	IFN-	IFN-	NNP
cord-263862-zzys31e9	180	34	␥	␥	NNP
cord-263862-zzys31e9	180	35	in	in	IN
cord-263862-zzys31e9	180	36	response	response	NN
cord-263862-zzys31e9	180	37	to	to	IN
cord-263862-zzys31e9	180	38	an	an	DT
cord-263862-zzys31e9	180	39	i.m	i.m	NNP
cord-263862-zzys31e9	180	40	.	.	NNP
cord-263862-zzys31e9	180	41	injection	injection	NN
cord-263862-zzys31e9	180	42	of	of	IN
cord-263862-zzys31e9	180	43	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	180	44	.	.	.
cord-263862-zzys31e9	181	1	NK	NK	NNP
cord-263862-zzys31e9	181	2	cell	cell	NN
cord-263862-zzys31e9	181	3	depletion	depletion	NN
cord-263862-zzys31e9	181	4	was	be	VBD
cord-263862-zzys31e9	181	5	achieved	achieve	VBN
cord-263862-zzys31e9	181	6	using	use	VBG
cord-263862-zzys31e9	181	7	two	two	CD
cord-263862-zzys31e9	181	8	doses	dose	NNS
cord-263862-zzys31e9	181	9	of	of	IN
cord-263862-zzys31e9	181	10	a	a	DT
cord-263862-zzys31e9	181	11	polyclonal	polyclonal	JJ
cord-263862-zzys31e9	181	12	anti	anti	JJ
cord-263862-zzys31e9	181	13	-	-	JJ
cord-263862-zzys31e9	181	14	asialo	asialo	JJ
cord-263862-zzys31e9	181	15	-	-	HYPH
cord-263862-zzys31e9	181	16	GM1	GM1	NNP
cord-263862-zzys31e9	181	17	Ab	Ab	NNP
cord-263862-zzys31e9	181	18	,	,	,
cord-263862-zzys31e9	181	19	one	one	CD
cord-263862-zzys31e9	181	20	given	give	VBN
cord-263862-zzys31e9	181	21	5	5	CD
cord-263862-zzys31e9	181	22	days	day	NNS
cord-263862-zzys31e9	181	23	before	before	RB
cord-263862-zzys31e9	181	24	and	and	CC
cord-263862-zzys31e9	181	25	the	the	DT
cord-263862-zzys31e9	181	26	second	second	JJ
cord-263862-zzys31e9	181	27	together	together	RB
cord-263862-zzys31e9	181	28	with	with	IN
cord-263862-zzys31e9	181	29	the	the	DT
cord-263862-zzys31e9	181	30	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	181	31	injection	injection	NN
cord-263862-zzys31e9	181	32	.	.	.
cord-263862-zzys31e9	182	1	The	the	DT
cord-263862-zzys31e9	182	2	efficacy	efficacy	NN
cord-263862-zzys31e9	182	3	of	of	IN
cord-263862-zzys31e9	182	4	this	this	DT
cord-263862-zzys31e9	182	5	depletion	depletion	NN
cord-263862-zzys31e9	182	6	is	be	VBZ
cord-263862-zzys31e9	182	7	illustrated	illustrate	VBN
cord-263862-zzys31e9	182	8	by	by	IN
cord-263862-zzys31e9	182	9	the	the	DT
cord-263862-zzys31e9	182	10	lack	lack	NN
cord-263862-zzys31e9	182	11	of	of	IN
cord-263862-zzys31e9	182	12	CD49b	CD49b	NNP
cord-263862-zzys31e9	182	13	(	(	-LRB-
cord-263862-zzys31e9	182	14	a	a	DT
cord-263862-zzys31e9	182	15	NK	NK	NNP
cord-263862-zzys31e9	182	16	cell	cell	NN
cord-263862-zzys31e9	182	17	specific	specific	JJ
cord-263862-zzys31e9	182	18	marker	marker	NN
cord-263862-zzys31e9	182	19	in	in	IN
cord-263862-zzys31e9	182	20	Balb	Balb	NNP
cord-263862-zzys31e9	182	21	/	/	SYM
cord-263862-zzys31e9	182	22	c	c	NN
cord-263862-zzys31e9	182	23	mice	mouse	NNS
cord-263862-zzys31e9	182	24	)	)	-RRB-
cord-263862-zzys31e9	182	25	expressing	express	VBG
cord-263862-zzys31e9	182	26	cells	cell	NNS
cord-263862-zzys31e9	182	27	in	in	IN
cord-263862-zzys31e9	182	28	the	the	DT
cord-263862-zzys31e9	182	29	spleens	spleen	NNS
cord-263862-zzys31e9	182	30	of	of	IN
cord-263862-zzys31e9	183	1	anti	anti	JJ
cord-263862-zzys31e9	183	2	-	-	JJ
cord-263862-zzys31e9	183	3	asislo	asislo	JJ
cord-263862-zzys31e9	183	4	-	-	HYPH
cord-263862-zzys31e9	183	5	GM1	GM1	NNP
cord-263862-zzys31e9	183	6	treated	treat	VBD
cord-263862-zzys31e9	183	7	mice	mouse	NNS
cord-263862-zzys31e9	183	8	compared	compare	VBN
cord-263862-zzys31e9	183	9	with	with	IN
cord-263862-zzys31e9	183	10	mice	mouse	NNS
cord-263862-zzys31e9	183	11	treated	treat	VBN
cord-263862-zzys31e9	183	12	with	with	IN
cord-263862-zzys31e9	183	13	an	an	DT
cord-263862-zzys31e9	183	14	isotype	isotype	NN
cord-263862-zzys31e9	183	15	control	control	NN
cord-263862-zzys31e9	183	16	antibody	antibody	NN
cord-263862-zzys31e9	183	17	(	(	-LRB-
cord-263862-zzys31e9	183	18	Fig	Fig	NNP
cord-263862-zzys31e9	183	19	.	.	.
cord-263862-zzys31e9	183	20	4B	4b	CD
cord-263862-zzys31e9	183	21	)	)	-RRB-
cord-263862-zzys31e9	183	22	.	.	.
cord-263862-zzys31e9	184	1	Groups	group	NNS
cord-263862-zzys31e9	184	2	of	of	IN
cord-263862-zzys31e9	184	3	mice	mouse	NNS
cord-263862-zzys31e9	184	4	,	,	,
cord-263862-zzys31e9	184	5	either	either	CC
cord-263862-zzys31e9	184	6	NK	NK	NNP
cord-263862-zzys31e9	184	7	cell	cell	NN
cord-263862-zzys31e9	184	8	depleted	deplete	VBN
cord-263862-zzys31e9	184	9	or	or	CC
cord-263862-zzys31e9	184	10	not	not	RB
cord-263862-zzys31e9	184	11	,	,	,
cord-263862-zzys31e9	184	12	were	be	VBD
cord-263862-zzys31e9	184	13	immunised	immunise	VBN
cord-263862-zzys31e9	184	14	with	with	IN
cord-263862-zzys31e9	184	15	Placebo	Placebo	NNP
cord-263862-zzys31e9	184	16	or	or	CC
cord-263862-zzys31e9	184	17	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	184	18	and	and	CC
cord-263862-zzys31e9	184	19	were	be	VBD
cord-263862-zzys31e9	184	20	given	give	VBN
cord-263862-zzys31e9	184	21	a	a	DT
cord-263862-zzys31e9	184	22	simultaneous	simultaneous	JJ
cord-263862-zzys31e9	184	23	i.p	i.p	NNP
cord-263862-zzys31e9	184	24	.	.	NNP
cord-263862-zzys31e9	184	25	injection	injection	NN
cord-263862-zzys31e9	184	26	of	of	IN
cord-263862-zzys31e9	185	1	biotin	biotin	NN
cord-263862-zzys31e9	185	2	-	-	HYPH
cord-263862-zzys31e9	185	3	anti	anti	NN
cord-263862-zzys31e9	185	4	-	-	JJ
cord-263862-zzys31e9	185	5	IFN-	ifn-	JJ
cord-263862-zzys31e9	185	6	␥	␥	CD
cord-263862-zzys31e9	185	7	.	.	.
cord-263862-zzys31e9	186	1	After	after	IN
cord-263862-zzys31e9	186	2	3	3	CD
cord-263862-zzys31e9	186	3	days	day	NNS
cord-263862-zzys31e9	186	4	,	,	,
cord-263862-zzys31e9	186	5	the	the	DT
cord-263862-zzys31e9	186	6	mice	mouse	NNS
cord-263862-zzys31e9	186	7	were	be	VBD
cord-263862-zzys31e9	186	8	sacrificed	sacrifice	VBN
cord-263862-zzys31e9	186	9	and	and	CC
cord-263862-zzys31e9	186	10	their	-PRON-	PRP$
cord-263862-zzys31e9	186	11	serum	serum	NN
cord-263862-zzys31e9	186	12	analysed	analyse	VBN
cord-263862-zzys31e9	186	13	for	for	IN
cord-263862-zzys31e9	186	14	the	the	DT
cord-263862-zzys31e9	186	15	levels	level	NNS
cord-263862-zzys31e9	186	16	of	of	IN
cord-263862-zzys31e9	186	17	circulating	circulate	VBG
cord-263862-zzys31e9	186	18	IFN-	IFN-	NNP
cord-263862-zzys31e9	186	19	␥	␥	NNP
cord-263862-zzys31e9	186	20	:mAb	:mAb	NFP
cord-263862-zzys31e9	186	21	complex	complex	NN
cord-263862-zzys31e9	186	22	by	by	IN
cord-263862-zzys31e9	186	23	ELISA	ELISA	NNP
cord-263862-zzys31e9	186	24	.	.	.
cord-263862-zzys31e9	187	1	We	-PRON-	PRP
cord-263862-zzys31e9	187	2	found	find	VBD
cord-263862-zzys31e9	187	3	that	that	IN
cord-263862-zzys31e9	187	4	the	the	DT
cord-263862-zzys31e9	187	5	induction	induction	NN
cord-263862-zzys31e9	187	6	of	of	IN
cord-263862-zzys31e9	187	7	circulating	circulate	VBG
cord-263862-zzys31e9	187	8	IFN-	IFN-	NNP
cord-263862-zzys31e9	187	9	␥	␥	NNP
cord-263862-zzys31e9	187	10	by	by	IN
cord-263862-zzys31e9	187	11	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	187	12	was	be	VBD
cord-263862-zzys31e9	187	13	significantly	significantly	RB
cord-263862-zzys31e9	187	14	reduced	reduce	VBN
cord-263862-zzys31e9	187	15	following	follow	VBG
cord-263862-zzys31e9	187	16	NK	NK	NNP
cord-263862-zzys31e9	187	17	cell	cell	NN
cord-263862-zzys31e9	187	18	depletion	depletion	NN
cord-263862-zzys31e9	187	19	(	(	-LRB-
cord-263862-zzys31e9	187	20	Fig	Fig	NNP
cord-263862-zzys31e9	187	21	.	.	.
cord-263862-zzys31e9	187	22	4A	4a	CD
cord-263862-zzys31e9	187	23	)	)	-RRB-
cord-263862-zzys31e9	187	24	.	.	.
cord-263862-zzys31e9	188	1	This	this	DT
cord-263862-zzys31e9	188	2	indicates	indicate	VBZ
cord-263862-zzys31e9	188	3	that	that	IN
cord-263862-zzys31e9	188	4	NK	NK	NNP
cord-263862-zzys31e9	188	5	cells	cell	NNS
cord-263862-zzys31e9	188	6	Fig	Fig	NNP
cord-263862-zzys31e9	188	7	.	.	NNP
cord-263862-zzys31e9	188	8	4	4	CD
cord-263862-zzys31e9	188	9	.	.	.
cord-263862-zzys31e9	189	1	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	189	2	induction	induction	NN
cord-263862-zzys31e9	189	3	of	of	IN
cord-263862-zzys31e9	189	4	circulating	circulate	VBG
cord-263862-zzys31e9	189	5	innate	innate	JJ
cord-263862-zzys31e9	190	1	IFN-	IFN-	NNP
cord-263862-zzys31e9	190	2	␥	␥	NNP
cord-263862-zzys31e9	190	3	that	that	WDT
cord-263862-zzys31e9	190	4	is	be	VBZ
cord-263862-zzys31e9	190	5	dependent	dependent	JJ
cord-263862-zzys31e9	190	6	upon	upon	IN
cord-263862-zzys31e9	190	7	the	the	DT
cord-263862-zzys31e9	190	8	presence	presence	NN
cord-263862-zzys31e9	190	9	of	of	IN
cord-263862-zzys31e9	190	10	CD49b	CD49b	NNP
cord-263862-zzys31e9	190	11	+	+	CC
cord-263862-zzys31e9	190	12	NK	NK	NNP
cord-263862-zzys31e9	190	13	cells	cell	NNS
cord-263862-zzys31e9	190	14	.	.	.
cord-263862-zzys31e9	191	1	(	(	-LRB-
cord-263862-zzys31e9	191	2	A	a	NN
cord-263862-zzys31e9	191	3	)	)	-RRB-
cord-263862-zzys31e9	191	4	NK	NK	NNP
cord-263862-zzys31e9	191	5	cells	cell	NNS
cord-263862-zzys31e9	191	6	were	be	VBD
cord-263862-zzys31e9	191	7	depleted	deplete	VBN
cord-263862-zzys31e9	191	8	from	from	IN
cord-263862-zzys31e9	191	9	Balb	Balb	NNP
cord-263862-zzys31e9	191	10	/	/	SYM
cord-263862-zzys31e9	191	11	c	c	NN
cord-263862-zzys31e9	191	12	mice	mouse	NNS
cord-263862-zzys31e9	191	13	using	use	VBG
cord-263862-zzys31e9	191	14	polyclonal	polyclonal	JJ
cord-263862-zzys31e9	191	15	anti	anti	NNP
cord-263862-zzys31e9	191	16	-	-	JJ
cord-263862-zzys31e9	191	17	asialo	asialo	NNP
cord-263862-zzys31e9	191	18	GM1	GM1	NNP
cord-263862-zzys31e9	191	19	Antibody	Antibody	NNP
cord-263862-zzys31e9	191	20	.	.	.
cord-263862-zzys31e9	192	1	Mice	mouse	NNS
cord-263862-zzys31e9	192	2	were	be	VBD
cord-263862-zzys31e9	192	3	injected	inject	VBN
cord-263862-zzys31e9	192	4	i.p	i.p	NNP
cord-263862-zzys31e9	192	5	.	.	.
cord-263862-zzys31e9	193	1	with	with	IN
cord-263862-zzys31e9	193	2	30	30	CD
cord-263862-zzys31e9	193	3	g	g	NN
cord-263862-zzys31e9	193	4	of	of	IN
cord-263862-zzys31e9	193	5	antibody	antibody	NN
cord-263862-zzys31e9	193	6	at	at	IN
cord-263862-zzys31e9	193	7	day	day	NN
cord-263862-zzys31e9	193	8	−5	−5	NNP
cord-263862-zzys31e9	193	9	and	and	CC
cord-263862-zzys31e9	193	10	day	day	NN
cord-263862-zzys31e9	193	11	0	0	CD
cord-263862-zzys31e9	193	12	,	,	,
cord-263862-zzys31e9	193	13	rabbit	rabbit	NN
cord-263862-zzys31e9	193	14	IgG	igg	NN
cord-263862-zzys31e9	193	15	was	be	VBD
cord-263862-zzys31e9	193	16	used	use	VBN
cord-263862-zzys31e9	193	17	as	as	IN
cord-263862-zzys31e9	193	18	an	an	DT
cord-263862-zzys31e9	193	19	isotype	isotype	NN
cord-263862-zzys31e9	193	20	control	control	NN
cord-263862-zzys31e9	193	21	.	.	.
cord-263862-zzys31e9	194	1	On	on	IN
cord-263862-zzys31e9	194	2	day	day	NN
cord-263862-zzys31e9	194	3	0	0	CD
cord-263862-zzys31e9	194	4	biotinylated	biotinylate	VBN
cord-263862-zzys31e9	194	5	anti	anti	JJ
cord-263862-zzys31e9	194	6	-	-	JJ
cord-263862-zzys31e9	194	7	IFN-	ifn-	JJ
cord-263862-zzys31e9	194	8	␥	␥	NNP
cord-263862-zzys31e9	194	9	at	at	IN
cord-263862-zzys31e9	194	10	10	10	CD
cord-263862-zzys31e9	194	11	g	g	NN
cord-263862-zzys31e9	194	12	/	/	SYM
cord-263862-zzys31e9	194	13	dose	dose	NN
cord-263862-zzys31e9	194	14	was	be	VBD
cord-263862-zzys31e9	194	15	given	give	VBN
cord-263862-zzys31e9	194	16	i.p	i.p	NNP
cord-263862-zzys31e9	194	17	.	.	NNP
cord-263862-zzys31e9	194	18	to	to	IN
cord-263862-zzys31e9	194	19	all	all	DT
cord-263862-zzys31e9	194	20	animals	animal	NNS
cord-263862-zzys31e9	194	21	,	,	,
cord-263862-zzys31e9	194	22	and	and	CC
cord-263862-zzys31e9	194	23	then	then	RB
cord-263862-zzys31e9	194	24	the	the	DT
cord-263862-zzys31e9	194	25	various	various	JJ
cord-263862-zzys31e9	194	26	groups	group	NNS
cord-263862-zzys31e9	194	27	were	be	VBD
cord-263862-zzys31e9	194	28	immunised	immunise	VBN
cord-263862-zzys31e9	194	29	i.m	i.m	NNP
cord-263862-zzys31e9	194	30	.	.	.
cord-263862-zzys31e9	195	1	with	with	IN
cord-263862-zzys31e9	195	2	either	either	CC
cord-263862-zzys31e9	195	3	placebo	placebo	NN
cord-263862-zzys31e9	195	4	or	or	CC
cord-263862-zzys31e9	195	5	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	195	6	at	at	IN
cord-263862-zzys31e9	195	7	1/10	1/10	CD
cord-263862-zzys31e9	195	8	human	human	JJ
cord-263862-zzys31e9	195	9	dose	dose	NN
cord-263862-zzys31e9	195	10	.	.	.
cord-263862-zzys31e9	196	1	Serum	serum	NN
cord-263862-zzys31e9	196	2	samples	sample	NNS
cord-263862-zzys31e9	196	3	were	be	VBD
cord-263862-zzys31e9	196	4	prepared	prepare	VBN
cord-263862-zzys31e9	196	5	at	at	IN
cord-263862-zzys31e9	196	6	day	day	NN
cord-263862-zzys31e9	196	7	3	3	CD
cord-263862-zzys31e9	196	8	and	and	CC
cord-263862-zzys31e9	196	9	the	the	DT
cord-263862-zzys31e9	196	10	levels	level	NNS
cord-263862-zzys31e9	196	11	of	of	IN
cord-263862-zzys31e9	196	12	the	the	DT
cord-263862-zzys31e9	196	13	circulating	circulate	VBG
cord-263862-zzys31e9	196	14	IFN-	IFN-	NNP
cord-263862-zzys31e9	196	15	␥	␥	CD
cord-263862-zzys31e9	196	16	:antibody	:antibody	:
cord-263862-zzys31e9	196	17	complex	complex	JJ
cord-263862-zzys31e9	196	18	were	be	VBD
cord-263862-zzys31e9	196	19	determined	determine	VBN
cord-263862-zzys31e9	196	20	by	by	IN
cord-263862-zzys31e9	196	21	ELISA	ELISA	NNP
cord-263862-zzys31e9	196	22	.	.	.
cord-263862-zzys31e9	197	1	Values	value	NNS
cord-263862-zzys31e9	197	2	shown	show	VBN
cord-263862-zzys31e9	197	3	are	be	VBP
cord-263862-zzys31e9	197	4	the	the	DT
cord-263862-zzys31e9	197	5	mean	mean	JJ
cord-263862-zzys31e9	197	6	±	±	NNP
cord-263862-zzys31e9	197	7	standard	standard	JJ
cord-263862-zzys31e9	197	8	deviation	deviation	NN
cord-263862-zzys31e9	197	9	of	of	IN
cord-263862-zzys31e9	197	10	5	5	CD
cord-263862-zzys31e9	197	11	mice	mouse	NNS
cord-263862-zzys31e9	197	12	per	per	IN
cord-263862-zzys31e9	197	13	group	group	NN
cord-263862-zzys31e9	197	14	,	,	,
cord-263862-zzys31e9	197	15	*	*	NFP
cord-263862-zzys31e9	197	16	*	*	NFP
cord-263862-zzys31e9	197	17	*	*	NFP
cord-263862-zzys31e9	197	18	p	p	XX
cord-263862-zzys31e9	197	19	<	<	XX
cord-263862-zzys31e9	197	20	0.001	0.001	CD
cord-263862-zzys31e9	197	21	and	and	CC
cord-263862-zzys31e9	197	22	ns	ns	NNP
cord-263862-zzys31e9	197	23	=	=	NFP
cord-263862-zzys31e9	197	24	not	not	RB
cord-263862-zzys31e9	197	25	significant	significant	JJ
cord-263862-zzys31e9	197	26	.	.	.
cord-263862-zzys31e9	198	1	(	(	-LRB-
cord-263862-zzys31e9	198	2	B	b	NN
cord-263862-zzys31e9	198	3	)	)	-RRB-
cord-263862-zzys31e9	198	4	Treatment	treatment	NN
cord-263862-zzys31e9	198	5	with	with	IN
cord-263862-zzys31e9	198	6	Anti	Anti	NNP
cord-263862-zzys31e9	198	7	-	-	JJ
cord-263862-zzys31e9	198	8	asialo	asialo	NNP
cord-263862-zzys31e9	198	9	-	-	HYPH
cord-263862-zzys31e9	198	10	GM1	GM1	NNP
cord-263862-zzys31e9	198	11	Ab	Ab	NNP
cord-263862-zzys31e9	198	12	reduced	reduce	VBD
cord-263862-zzys31e9	198	13	the	the	DT
cord-263862-zzys31e9	198	14	%	%	NN
cord-263862-zzys31e9	198	15	CD49b	CD49b	NNS
cord-263862-zzys31e9	198	16	+	+	SYM
cord-263862-zzys31e9	198	17	cells	cell	NNS
cord-263862-zzys31e9	198	18	in	in	IN
cord-263862-zzys31e9	198	19	the	the	DT
cord-263862-zzys31e9	198	20	spleens	spleen	NNS
cord-263862-zzys31e9	198	21	of	of	IN
cord-263862-zzys31e9	198	22	the	the	DT
cord-263862-zzys31e9	198	23	treated	treat	VBN
cord-263862-zzys31e9	198	24	mice	mouse	NNS
cord-263862-zzys31e9	198	25	from	from	IN
cord-263862-zzys31e9	198	26	3.381	3.381	CD
cord-263862-zzys31e9	198	27	%	%	NN
cord-263862-zzys31e9	198	28	(	(	-LRB-
cord-263862-zzys31e9	198	29	±0.38	±0.38	NNP
cord-263862-zzys31e9	198	30	)	)	-RRB-
cord-263862-zzys31e9	198	31	in	in	IN
cord-263862-zzys31e9	198	32	the	the	DT
cord-263862-zzys31e9	198	33	control	control	NN
cord-263862-zzys31e9	198	34	treated	treat	VBD
cord-263862-zzys31e9	198	35	group	group	NN
cord-263862-zzys31e9	198	36	to	to	IN
cord-263862-zzys31e9	198	37	1.129	1.129	CD
cord-263862-zzys31e9	198	38	%	%	NN
cord-263862-zzys31e9	198	39	(	(	-LRB-
cord-263862-zzys31e9	198	40	±0.17	±0.17	NNS
cord-263862-zzys31e9	198	41	)	)	-RRB-
cord-263862-zzys31e9	198	42	in	in	IN
cord-263862-zzys31e9	198	43	the	the	DT
cord-263862-zzys31e9	198	44	anti	anti	JJ
cord-263862-zzys31e9	198	45	-	-	JJ
cord-263862-zzys31e9	198	46	asialoGM1	asialogm1	JJ
cord-263862-zzys31e9	198	47	treated	treat	VBN
cord-263862-zzys31e9	198	48	group	group	NN
cord-263862-zzys31e9	198	49	(	(	-LRB-
cord-263862-zzys31e9	198	50	the	the	DT
cord-263862-zzys31e9	198	51	average	average	NN
cord-263862-zzys31e9	198	52	of	of	IN
cord-263862-zzys31e9	198	53	10	10	CD
cord-263862-zzys31e9	198	54	mice	mouse	NNS
cord-263862-zzys31e9	198	55	/	/	SYM
cord-263862-zzys31e9	198	56	treatment	treatment	NN
cord-263862-zzys31e9	198	57	group	group	NN
cord-263862-zzys31e9	198	58	±	±	NNP
cord-263862-zzys31e9	198	59	standard	standard	JJ
cord-263862-zzys31e9	198	60	deviation	deviation	NN
cord-263862-zzys31e9	198	61	)	)	-RRB-
cord-263862-zzys31e9	198	62	.	.	.
cord-263862-zzys31e9	199	1	Spleen	spleen	NN
cord-263862-zzys31e9	199	2	cells	cell	NNS
cord-263862-zzys31e9	199	3	were	be	VBD
cord-263862-zzys31e9	199	4	isolated	isolate	VBN
cord-263862-zzys31e9	199	5	from	from	IN
cord-263862-zzys31e9	199	6	10	10	CD
cord-263862-zzys31e9	199	7	mice	mouse	NNS
cord-263862-zzys31e9	199	8	per	per	IN
cord-263862-zzys31e9	199	9	group	group	NN
cord-263862-zzys31e9	199	10	and	and	CC
cord-263862-zzys31e9	199	11	the	the	DT
cord-263862-zzys31e9	199	12	expression	expression	NN
cord-263862-zzys31e9	199	13	of	of	IN
cord-263862-zzys31e9	199	14	CD49b	CD49b	NNP
cord-263862-zzys31e9	199	15	determined	determine	VBN
cord-263862-zzys31e9	199	16	by	by	IN
cord-263862-zzys31e9	199	17	flow	flow	NN
cord-263862-zzys31e9	199	18	cytometry	cytometry	NN
cord-263862-zzys31e9	199	19	using	use	VBG
cord-263862-zzys31e9	199	20	a	a	DT
cord-263862-zzys31e9	199	21	PE	PE	NNP
cord-263862-zzys31e9	199	22	-	-	HYPH
cord-263862-zzys31e9	199	23	labelled	label	VBN
cord-263862-zzys31e9	199	24	specific	specific	JJ
cord-263862-zzys31e9	199	25	mAb	mAb	NNS
cord-263862-zzys31e9	199	26	.	.	.
cord-263862-zzys31e9	199	27	Quadrants	quadrant	NNS
cord-263862-zzys31e9	199	28	were	be	VBD
cord-263862-zzys31e9	199	29	determined	determine	VBN
cord-263862-zzys31e9	199	30	by	by	IN
cord-263862-zzys31e9	199	31	the	the	DT
cord-263862-zzys31e9	199	32	staining	staining	NN
cord-263862-zzys31e9	199	33	of	of	IN
cord-263862-zzys31e9	199	34	the	the	DT
cord-263862-zzys31e9	199	35	isotype	isotype	NN
cord-263862-zzys31e9	199	36	control	control	NN
cord-263862-zzys31e9	199	37	antibodies	antibody	NNS
cord-263862-zzys31e9	199	38	;	;	:
cord-263862-zzys31e9	199	39	representative	representative	NNP
cord-263862-zzys31e9	199	40	FACs	FACs	NNP
cord-263862-zzys31e9	199	41	plots	plot	NNS
cord-263862-zzys31e9	199	42	of	of	IN
cord-263862-zzys31e9	199	43	10	10	CD
cord-263862-zzys31e9	199	44	per	per	IN
cord-263862-zzys31e9	199	45	treatment	treatment	NN
cord-263862-zzys31e9	199	46	are	be	VBP
cord-263862-zzys31e9	199	47	shown	show	VBN
cord-263862-zzys31e9	199	48	.	.	.
cord-263862-zzys31e9	200	1	are	be	VBP
cord-263862-zzys31e9	200	2	the	the	DT
cord-263862-zzys31e9	200	3	primary	primary	JJ
cord-263862-zzys31e9	200	4	source	source	NN
cord-263862-zzys31e9	200	5	of	of	IN
cord-263862-zzys31e9	200	6	the	the	DT
cord-263862-zzys31e9	200	7	IFN-	IFN-	NNP
cord-263862-zzys31e9	200	8	␥	␥	CD
cord-263862-zzys31e9	200	9	secreted	secrete	VBN
cord-263862-zzys31e9	200	10	in	in	IN
cord-263862-zzys31e9	200	11	response	response	NN
cord-263862-zzys31e9	200	12	to	to	IN
cord-263862-zzys31e9	200	13	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	200	14	within	within	IN
cord-263862-zzys31e9	200	15	the	the	DT
cord-263862-zzys31e9	200	16	first	first	JJ
cord-263862-zzys31e9	200	17	72	72	CD
cord-263862-zzys31e9	200	18	h	h	NN
cord-263862-zzys31e9	200	19	of	of	IN
cord-263862-zzys31e9	200	20	immunisation	immunisation	NN
cord-263862-zzys31e9	200	21	.	.	.
cord-263862-zzys31e9	201	1	Activated	activate	VBN
cord-263862-zzys31e9	201	2	DCs	dc	NNS
cord-263862-zzys31e9	201	3	augment	augment	VBP
cord-263862-zzys31e9	201	4	IFN-	IFN-	NNP
cord-263862-zzys31e9	201	5	␥	␥	CD
cord-263862-zzys31e9	201	6	production	production	NN
cord-263862-zzys31e9	201	7	by	by	IN
cord-263862-zzys31e9	201	8	NK	NK	NNP
cord-263862-zzys31e9	201	9	cells	cell	NNS
cord-263862-zzys31e9	201	10	[	[	-LRB-
cord-263862-zzys31e9	201	11	10	10	CD
cord-263862-zzys31e9	201	12	]	]	-RRB-
cord-263862-zzys31e9	201	13	.	.	.
cord-263862-zzys31e9	202	1	Therefore	therefore	RB
cord-263862-zzys31e9	202	2	,	,	,
cord-263862-zzys31e9	202	3	we	-PRON-	PRP
cord-263862-zzys31e9	202	4	wished	wish	VBD
cord-263862-zzys31e9	202	5	to	to	TO
cord-263862-zzys31e9	202	6	investigate	investigate	VB
cord-263862-zzys31e9	202	7	if	if	IN
cord-263862-zzys31e9	202	8	the	the	DT
cord-263862-zzys31e9	202	9	exposure	exposure	NN
cord-263862-zzys31e9	202	10	to	to	IN
cord-263862-zzys31e9	202	11	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	202	12	activates	activate	VBZ
cord-263862-zzys31e9	202	13	DCs	dc	NNS
cord-263862-zzys31e9	202	14	.	.	.
cord-263862-zzys31e9	203	1	In	in	IN
cord-263862-zzys31e9	203	2	order	order	NN
cord-263862-zzys31e9	203	3	for	for	IN
cord-263862-zzys31e9	203	4	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	203	5	to	to	TO
cord-263862-zzys31e9	203	6	act	act	VB
cord-263862-zzys31e9	203	7	as	as	IN
cord-263862-zzys31e9	203	8	an	an	DT
cord-263862-zzys31e9	203	9	effective	effective	JJ
cord-263862-zzys31e9	203	10	vaccine	vaccine	NN
cord-263862-zzys31e9	203	11	vector	vector	NN
cord-263862-zzys31e9	203	12	it	-PRON-	PRP
cord-263862-zzys31e9	203	13	must	must	MD
cord-263862-zzys31e9	203	14	infect	infect	VB
cord-263862-zzys31e9	203	15	the	the	DT
cord-263862-zzys31e9	203	16	host	host	NN
cord-263862-zzys31e9	203	17	cells	cell	NNS
cord-263862-zzys31e9	203	18	in	in	IN
cord-263862-zzys31e9	203	19	order	order	NN
cord-263862-zzys31e9	203	20	to	to	TO
cord-263862-zzys31e9	203	21	produce	produce	VB
cord-263862-zzys31e9	203	22	the	the	DT
cord-263862-zzys31e9	203	23	antigens	antigen	NNS
cord-263862-zzys31e9	203	24	which	which	WDT
cord-263862-zzys31e9	203	25	are	be	VBP
cord-263862-zzys31e9	203	26	integrated	integrate	VBN
cord-263862-zzys31e9	203	27	in	in	IN
cord-263862-zzys31e9	203	28	its	-PRON-	PRP$
cord-263862-zzys31e9	203	29	genome	genome	NN
cord-263862-zzys31e9	203	30	.	.	.
cord-263862-zzys31e9	204	1	However	however	RB
cord-263862-zzys31e9	204	2	,	,	,
cord-263862-zzys31e9	204	3	here	here	RB
cord-263862-zzys31e9	204	4	as	as	IN
cord-263862-zzys31e9	204	5	we	-PRON-	PRP
cord-263862-zzys31e9	204	6	are	be	VBP
cord-263862-zzys31e9	204	7	examining	examine	VBG
cord-263862-zzys31e9	204	8	the	the	DT
cord-263862-zzys31e9	204	9	adjuvant	adjuvant	JJ
cord-263862-zzys31e9	204	10	effect	effect	NN
cord-263862-zzys31e9	204	11	of	of	IN
cord-263862-zzys31e9	204	12	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	204	13	we	-PRON-	PRP
cord-263862-zzys31e9	204	14	are	be	VBP
cord-263862-zzys31e9	204	15	interested	interested	JJ
cord-263862-zzys31e9	204	16	in	in	IN
cord-263862-zzys31e9	204	17	investigating	investigate	VBG
cord-263862-zzys31e9	204	18	the	the	DT
cord-263862-zzys31e9	204	19	immuno	immuno	JJ
cord-263862-zzys31e9	204	20	-	-	JJ
cord-263862-zzys31e9	204	21	modulatory	modulatory	JJ
cord-263862-zzys31e9	204	22	effects	effect	NNS
cord-263862-zzys31e9	204	23	of	of	IN
cord-263862-zzys31e9	204	24	exposing	expose	VBG
cord-263862-zzys31e9	204	25	cells	cell	NNS
cord-263862-zzys31e9	204	26	to	to	IN
cord-263862-zzys31e9	204	27	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	204	28	without	without	IN
cord-263862-zzys31e9	204	29	them	-PRON-	PRP
cord-263862-zzys31e9	204	30	necessarily	necessarily	RB
cord-263862-zzys31e9	204	31	becoming	become	VBG
cord-263862-zzys31e9	204	32	infected	infect	VBN
cord-263862-zzys31e9	204	33	.	.	.
cord-263862-zzys31e9	205	1	In	in	IN
cord-263862-zzys31e9	205	2	addition	addition	NN
cord-263862-zzys31e9	205	3	in	in	IN
cord-263862-zzys31e9	205	4	vitro	vitro	FW
cord-263862-zzys31e9	205	5	infection	infection	NN
cord-263862-zzys31e9	205	6	protocols	protocol	NNS
cord-263862-zzys31e9	205	7	using	use	VBG
cord-263862-zzys31e9	205	8	low	low	JJ
cord-263862-zzys31e9	205	9	or	or	CC
cord-263862-zzys31e9	205	10	no	no	DT
cord-263862-zzys31e9	205	11	serum	serum	NN
cord-263862-zzys31e9	205	12	conditions	condition	NNS
cord-263862-zzys31e9	205	13	and	and	CC
cord-263862-zzys31e9	205	14	a	a	DT
cord-263862-zzys31e9	205	15	high	high	JJ
cord-263862-zzys31e9	205	16	MOI	MOI	NNP
cord-263862-zzys31e9	205	17	have	have	VBP
cord-263862-zzys31e9	205	18	been	be	VBN
cord-263862-zzys31e9	205	19	shown	show	VBN
cord-263862-zzys31e9	205	20	to	to	TO
cord-263862-zzys31e9	205	21	induce	induce	VB
cord-263862-zzys31e9	205	22	apoptosis	apoptosis	NN
cord-263862-zzys31e9	205	23	in	in	IN
cord-263862-zzys31e9	205	24	the	the	DT
cord-263862-zzys31e9	205	25	target	target	NN
cord-263862-zzys31e9	205	26	cells	cell	NNS
cord-263862-zzys31e9	205	27	[	[	-LRB-
cord-263862-zzys31e9	205	28	9	9	CD
cord-263862-zzys31e9	205	29	]	]	-RRB-
cord-263862-zzys31e9	205	30	.	.	.
cord-263862-zzys31e9	206	1	Preliminary	preliminary	JJ
cord-263862-zzys31e9	206	2	experiments	experiment	NNS
cord-263862-zzys31e9	206	3	showed	show	VBD
cord-263862-zzys31e9	206	4	that	that	IN
cord-263862-zzys31e9	206	5	a	a	DT
cord-263862-zzys31e9	206	6	MOI	MOI	NNP
cord-263862-zzys31e9	206	7	of	of	IN
cord-263862-zzys31e9	206	8	0.2	0.2	CD
cord-263862-zzys31e9	206	9	to	to	IN
cord-263862-zzys31e9	206	10	1	1	CD
cord-263862-zzys31e9	206	11	did	do	VBD
cord-263862-zzys31e9	206	12	not	not	RB
cord-263862-zzys31e9	206	13	induce	induce	VB
cord-263862-zzys31e9	206	14	significant	significant	JJ
cord-263862-zzys31e9	206	15	cell	cell	NN
cord-263862-zzys31e9	206	16	death	death	NN
cord-263862-zzys31e9	206	17	in	in	IN
cord-263862-zzys31e9	206	18	murine	murine	JJ
cord-263862-zzys31e9	206	19	bone	bone	NN
cord-263862-zzys31e9	206	20	-	-	HYPH
cord-263862-zzys31e9	206	21	marrow	marrow	NN
cord-263862-zzys31e9	206	22	derived	derive	VBN
cord-263862-zzys31e9	206	23	DCs	dc	NNS
cord-263862-zzys31e9	206	24	(	(	-LRB-
cord-263862-zzys31e9	206	25	BMDCs	BMDCs	NNP
cord-263862-zzys31e9	206	26	)	)	-RRB-
cord-263862-zzys31e9	206	27	over	over	IN
cord-263862-zzys31e9	206	28	a	a	DT
cord-263862-zzys31e9	206	29	culture	culture	NN
cord-263862-zzys31e9	206	30	period	period	NN
cord-263862-zzys31e9	206	31	of	of	IN
cord-263862-zzys31e9	206	32	24	24	CD
cord-263862-zzys31e9	206	33	h	h	NNP
cord-263862-zzys31e9	206	34	(	(	-LRB-
cord-263862-zzys31e9	206	35	data	datum	NNS
cord-263862-zzys31e9	206	36	not	not	RB
cord-263862-zzys31e9	206	37	shown	show	VBN
cord-263862-zzys31e9	206	38	)	)	-RRB-
cord-263862-zzys31e9	206	39	.	.	.
cord-263862-zzys31e9	207	1	Murine	murine	JJ
cord-263862-zzys31e9	207	2	BMDCs	bmdc	NNS
cord-263862-zzys31e9	207	3	were	be	VBD
cord-263862-zzys31e9	207	4	cultured	culture	VBN
cord-263862-zzys31e9	207	5	for	for	IN
cord-263862-zzys31e9	207	6	24	24	CD
cord-263862-zzys31e9	207	7	h	h	NN
cord-263862-zzys31e9	207	8	at	at	IN
cord-263862-zzys31e9	207	9	a	a	DT
cord-263862-zzys31e9	207	10	concentration	concentration	NN
cord-263862-zzys31e9	207	11	of	of	IN
cord-263862-zzys31e9	207	12	10	10	CD
cord-263862-zzys31e9	207	13	6	6	CD
cord-263862-zzys31e9	207	14	cells	cell	NNS
cord-263862-zzys31e9	207	15	/	/	SYM
cord-263862-zzys31e9	207	16	ml	ml	NNS
cord-263862-zzys31e9	207	17	in	in	IN
cord-263862-zzys31e9	207	18	complete	complete	JJ
cord-263862-zzys31e9	207	19	RPMI	RPMI	NNP
cord-263862-zzys31e9	207	20	supplemented	supplement	VBN
cord-263862-zzys31e9	207	21	with	with	IN
cord-263862-zzys31e9	207	22	10	10	CD
cord-263862-zzys31e9	207	23	%	%	NN
cord-263862-zzys31e9	207	24	FCS	FCS	NNP
cord-263862-zzys31e9	207	25	alone	alone	RB
cord-263862-zzys31e9	207	26	or	or	CC
cord-263862-zzys31e9	207	27	with	with	IN
cord-263862-zzys31e9	207	28	the	the	DT
cord-263862-zzys31e9	207	29	addition	addition	NN
cord-263862-zzys31e9	207	30	of	of	IN
cord-263862-zzys31e9	207	31	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	207	32	with	with	IN
cord-263862-zzys31e9	207	33	a	a	DT
cord-263862-zzys31e9	207	34	MOI	moi	NN
cord-263862-zzys31e9	207	35	of	of	IN
cord-263862-zzys31e9	207	36	0.2	0.2	CD
cord-263862-zzys31e9	207	37	,	,	,
cord-263862-zzys31e9	207	38	the	the	DT
cord-263862-zzys31e9	207	39	equivalent	equivalent	JJ
cord-263862-zzys31e9	207	40	volume	volume	NN
cord-263862-zzys31e9	207	41	of	of	IN
cord-263862-zzys31e9	207	42	Placebo	Placebo	NNP
cord-263862-zzys31e9	207	43	or	or	CC
cord-263862-zzys31e9	207	44	with	with	IN
cord-263862-zzys31e9	207	45	a	a	DT
cord-263862-zzys31e9	207	46	TLR4	TLR4	NNP
cord-263862-zzys31e9	207	47	agonist	agonist	NN
cord-263862-zzys31e9	207	48	as	as	IN
cord-263862-zzys31e9	207	49	a	a	DT
cord-263862-zzys31e9	207	50	positive	positive	JJ
cord-263862-zzys31e9	207	51	control	control	NN
cord-263862-zzys31e9	207	52	.	.	.
cord-263862-zzys31e9	208	1	Cells	cell	NNS
cord-263862-zzys31e9	208	2	were	be	VBD
cord-263862-zzys31e9	208	3	then	then	RB
cord-263862-zzys31e9	208	4	stained	stain	VBN
cord-263862-zzys31e9	208	5	with	with	IN
cord-263862-zzys31e9	208	6	fluorescently	fluorescently	RB
cord-263862-zzys31e9	208	7	labelled	label	VBN
cord-263862-zzys31e9	208	8	mAbs	mAbs	NNP
cord-263862-zzys31e9	208	9	specific	specific	JJ
cord-263862-zzys31e9	208	10	for	for	IN
cord-263862-zzys31e9	208	11	the	the	DT
cord-263862-zzys31e9	208	12	co	co	JJ
cord-263862-zzys31e9	208	13	-	-	JJ
cord-263862-zzys31e9	208	14	stimulatory	stimulatory	JJ
cord-263862-zzys31e9	208	15	molecules	molecule	NNS
cord-263862-zzys31e9	208	16	CD40	CD40	NNP
cord-263862-zzys31e9	208	17	,	,	,
cord-263862-zzys31e9	208	18	CD80	CD80	NNP
cord-263862-zzys31e9	208	19	and	and	CC
cord-263862-zzys31e9	208	20	CD86	CD86	NNP
cord-263862-zzys31e9	208	21	and	and	CC
cord-263862-zzys31e9	208	22	their	-PRON-	PRP$
cord-263862-zzys31e9	208	23	expression	expression	NN
cord-263862-zzys31e9	208	24	levels	level	NNS
cord-263862-zzys31e9	208	25	were	be	VBD
cord-263862-zzys31e9	208	26	analysed	analyse	VBN
cord-263862-zzys31e9	208	27	by	by	IN
cord-263862-zzys31e9	208	28	flow	flow	NN
cord-263862-zzys31e9	208	29	cytometry	cytometry	NN
cord-263862-zzys31e9	208	30	.	.	.
cord-263862-zzys31e9	209	1	The	the	DT
cord-263862-zzys31e9	209	2	percentage	percentage	NN
cord-263862-zzys31e9	209	3	of	of	IN
cord-263862-zzys31e9	209	4	BMDCs	bmdc	NNS
cord-263862-zzys31e9	209	5	expressing	express	VBG
cord-263862-zzys31e9	209	6	co	co	JJ
cord-263862-zzys31e9	209	7	-	-	JJ
cord-263862-zzys31e9	209	8	stimulatory	stimulatory	JJ
cord-263862-zzys31e9	209	9	molecules	molecule	NNS
cord-263862-zzys31e9	209	10	(	(	-LRB-
cord-263862-zzys31e9	209	11	CD40	CD40	NNP
cord-263862-zzys31e9	209	12	,	,	,
cord-263862-zzys31e9	209	13	CD80	CD80	NNP
cord-263862-zzys31e9	209	14	and	and	CC
cord-263862-zzys31e9	209	15	CD86	CD86	NNP
cord-263862-zzys31e9	209	16	)	)	-RRB-
cord-263862-zzys31e9	209	17	was	be	VBD
cord-263862-zzys31e9	209	18	significantly	significantly	RB
cord-263862-zzys31e9	209	19	increased	increase	VBN
cord-263862-zzys31e9	209	20	following	follow	VBG
cord-263862-zzys31e9	209	21	exposure	exposure	NN
cord-263862-zzys31e9	209	22	to	to	IN
cord-263862-zzys31e9	209	23	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	209	24	compared	compare	VBN
cord-263862-zzys31e9	209	25	to	to	IN
cord-263862-zzys31e9	209	26	medium	medium	NN
cord-263862-zzys31e9	209	27	alone	alone	RB
cord-263862-zzys31e9	209	28	or	or	CC
cord-263862-zzys31e9	209	29	Placebo	Placebo	NNP
cord-263862-zzys31e9	209	30	(	(	-LRB-
cord-263862-zzys31e9	209	31	Fig	Fig	NNP
cord-263862-zzys31e9	209	32	.	.	.
cord-263862-zzys31e9	209	33	5A	5a	CD
cord-263862-zzys31e9	209	34	-	-	HYPH
cord-263862-zzys31e9	209	35	C	C	NNP
cord-263862-zzys31e9	209	36	)	)	-RRB-
cord-263862-zzys31e9	209	37	.	.	.
cord-263862-zzys31e9	210	1	However	however	RB
cord-263862-zzys31e9	210	2	,	,	,
cord-263862-zzys31e9	210	3	the	the	DT
cord-263862-zzys31e9	210	4	enhancement	enhancement	NN
cord-263862-zzys31e9	210	5	of	of	IN
cord-263862-zzys31e9	210	6	costimulatory	costimulatory	NNP
cord-263862-zzys31e9	210	7	molecule	molecule	NN
cord-263862-zzys31e9	210	8	expression	expression	NN
cord-263862-zzys31e9	210	9	induced	induce	VBN
cord-263862-zzys31e9	210	10	by	by	IN
cord-263862-zzys31e9	210	11	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	210	12	was	be	VBD
cord-263862-zzys31e9	210	13	weaker	weak	JJR
cord-263862-zzys31e9	210	14	than	than	IN
cord-263862-zzys31e9	210	15	that	that	DT
cord-263862-zzys31e9	210	16	observed	observe	VBD
cord-263862-zzys31e9	210	17	following	follow	VBG
cord-263862-zzys31e9	210	18	the	the	DT
cord-263862-zzys31e9	210	19	stimulation	stimulation	NN
cord-263862-zzys31e9	210	20	of	of	IN
cord-263862-zzys31e9	210	21	BMDCs	bmdc	NNS
cord-263862-zzys31e9	210	22	with	with	IN
cord-263862-zzys31e9	210	23	a	a	DT
cord-263862-zzys31e9	210	24	TLR4	TLR4	NNP
cord-263862-zzys31e9	210	25	agonist	agonist	NN
cord-263862-zzys31e9	210	26	(	(	-LRB-
cord-263862-zzys31e9	210	27	Fig	Fig	NNP
cord-263862-zzys31e9	210	28	.	.	.
cord-263862-zzys31e9	210	29	5A	5a	CD
cord-263862-zzys31e9	210	30	-	-	HYPH
cord-263862-zzys31e9	210	31	C	C	NNP
cord-263862-zzys31e9	210	32	)	)	-RRB-
cord-263862-zzys31e9	210	33	.	.	.
cord-263862-zzys31e9	211	1	Nonetheless	nonetheless	RB
cord-263862-zzys31e9	211	2	,	,	,
cord-263862-zzys31e9	211	3	these	these	DT
cord-263862-zzys31e9	211	4	data	datum	NNS
cord-263862-zzys31e9	211	5	illustrate	illustrate	VBP
cord-263862-zzys31e9	211	6	that	that	IN
cord-263862-zzys31e9	211	7	exposure	exposure	NN
cord-263862-zzys31e9	211	8	to	to	IN
cord-263862-zzys31e9	211	9	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	211	10	activates	activate	VBZ
cord-263862-zzys31e9	211	11	DCs	dc	NNS
cord-263862-zzys31e9	211	12	.	.	.
cord-263862-zzys31e9	212	1	Activated	activate	VBN
cord-263862-zzys31e9	212	2	DCs	DCs	NNP
cord-263862-zzys31e9	212	3	secrete	secrete	VBP
cord-263862-zzys31e9	212	4	inflammatory	inflammatory	JJ
cord-263862-zzys31e9	212	5	cytokines	cytokine	NNS
cord-263862-zzys31e9	212	6	and	and	CC
cord-263862-zzys31e9	212	7	chemokines	chemokine	NNS
cord-263862-zzys31e9	212	8	to	to	TO
cord-263862-zzys31e9	212	9	recruit	recruit	VB
cord-263862-zzys31e9	212	10	and	and	CC
cord-263862-zzys31e9	212	11	activate	activate	VB
cord-263862-zzys31e9	212	12	the	the	DT
cord-263862-zzys31e9	212	13	cells	cell	NNS
cord-263862-zzys31e9	212	14	of	of	IN
cord-263862-zzys31e9	212	15	both	both	CC
cord-263862-zzys31e9	212	16	the	the	DT
cord-263862-zzys31e9	212	17	innate	innate	JJ
cord-263862-zzys31e9	212	18	and	and	CC
cord-263862-zzys31e9	212	19	adaptive	adaptive	JJ
cord-263862-zzys31e9	212	20	immune	immune	JJ
cord-263862-zzys31e9	212	21	response	response	NN
cord-263862-zzys31e9	212	22	.	.	.
cord-263862-zzys31e9	213	1	In	in	IN
cord-263862-zzys31e9	213	2	response	response	NN
cord-263862-zzys31e9	213	3	to	to	IN
cord-263862-zzys31e9	213	4	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	213	5	low	low	JJ
cord-263862-zzys31e9	213	6	amounts	amount	NNS
cord-263862-zzys31e9	213	7	of	of	IN
cord-263862-zzys31e9	213	8	the	the	DT
cord-263862-zzys31e9	213	9	pro	pro	JJ
cord-263862-zzys31e9	213	10	-	-	JJ
cord-263862-zzys31e9	213	11	inflammatory	inflammatory	JJ
cord-263862-zzys31e9	213	12	cytokines	cytokine	NNS
cord-263862-zzys31e9	214	1	IL-6	IL-6	NNP
cord-263862-zzys31e9	214	2	,	,	,
cord-263862-zzys31e9	214	3	TNF-	TNF-	NNP
cord-263862-zzys31e9	214	4	␣	␣	NN
cord-263862-zzys31e9	214	5	and	and	CC
cord-263862-zzys31e9	214	6	IL-12p40	IL-12p40	NNP
cord-263862-zzys31e9	214	7	are	be	VBP
cord-263862-zzys31e9	214	8	produced	produce	VBN
cord-263862-zzys31e9	214	9	by	by	IN
cord-263862-zzys31e9	214	10	DCs	DCs	NNP
cord-263862-zzys31e9	214	11	,	,	,
cord-263862-zzys31e9	214	12	and	and	CC
cord-263862-zzys31e9	214	13	in	in	IN
cord-263862-zzys31e9	214	14	general	general	JJ
cord-263862-zzys31e9	214	15	the	the	DT
cord-263862-zzys31e9	214	16	amounts	amount	NNS
cord-263862-zzys31e9	214	17	are	be	VBP
cord-263862-zzys31e9	214	18	10-fold	10-fold	CD
cord-263862-zzys31e9	214	19	less	less	JJR
cord-263862-zzys31e9	214	20	than	than	IN
cord-263862-zzys31e9	214	21	those	those	DT
cord-263862-zzys31e9	214	22	induced	induce	VBN
cord-263862-zzys31e9	214	23	by	by	IN
cord-263862-zzys31e9	214	24	the	the	DT
cord-263862-zzys31e9	214	25	TLR4	TLR4	NNP
cord-263862-zzys31e9	214	26	agonist	agonist	NN
cord-263862-zzys31e9	214	27	used	use	VBD
cord-263862-zzys31e9	214	28	as	as	IN
cord-263862-zzys31e9	214	29	a	a	DT
cord-263862-zzys31e9	214	30	positive	positive	JJ
cord-263862-zzys31e9	214	31	control	control	NN
cord-263862-zzys31e9	214	32	in	in	IN
cord-263862-zzys31e9	214	33	these	these	DT
cord-263862-zzys31e9	214	34	experiments	experiment	NNS
cord-263862-zzys31e9	214	35	(	(	-LRB-
cord-263862-zzys31e9	214	36	Fig	Fig	NNP
cord-263862-zzys31e9	214	37	.	.	.
cord-263862-zzys31e9	214	38	6D	6D	NNP
cord-263862-zzys31e9	214	39	-	-	HYPH
cord-263862-zzys31e9	214	40	F	F	NNP
cord-263862-zzys31e9	214	41	)	)	-RRB-
cord-263862-zzys31e9	214	42	.	.	.
cord-263862-zzys31e9	215	1	However	however	RB
cord-263862-zzys31e9	215	2	,	,	,
cord-263862-zzys31e9	215	3	the	the	DT
cord-263862-zzys31e9	215	4	levels	level	NNS
cord-263862-zzys31e9	215	5	of	of	IN
cord-263862-zzys31e9	215	6	the	the	DT
cord-263862-zzys31e9	215	7	chemokines	chemokine	NNS
cord-263862-zzys31e9	215	8	CXCL10	CXCL10	NNP
cord-263862-zzys31e9	215	9	and	and	CC
cord-263862-zzys31e9	215	10	CCL2	CCL2	NNP
cord-263862-zzys31e9	215	11	produced	produce	VBN
cord-263862-zzys31e9	215	12	by	by	IN
cord-263862-zzys31e9	215	13	BMDCs	bmdc	NNS
cord-263862-zzys31e9	215	14	following	follow	VBG
cord-263862-zzys31e9	215	15	incubation	incubation	NN
cord-263862-zzys31e9	215	16	with	with	IN
cord-263862-zzys31e9	215	17	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	215	18	exceeded	exceed	VBD
cord-263862-zzys31e9	215	19	or	or	CC
cord-263862-zzys31e9	215	20	were	be	VBD
cord-263862-zzys31e9	215	21	equivalent	equivalent	JJ
cord-263862-zzys31e9	215	22	to	to	IN
cord-263862-zzys31e9	215	23	those	those	DT
cord-263862-zzys31e9	215	24	induced	induce	VBN
cord-263862-zzys31e9	215	25	by	by	IN
cord-263862-zzys31e9	215	26	the	the	DT
cord-263862-zzys31e9	215	27	TLR4	TLR4	NNP
cord-263862-zzys31e9	215	28	agonist	agonist	NN
cord-263862-zzys31e9	215	29	(	(	-LRB-
cord-263862-zzys31e9	215	30	Fig	Fig	NNP
cord-263862-zzys31e9	215	31	.	.	.
cord-263862-zzys31e9	215	32	6A	6a	NN
cord-263862-zzys31e9	215	33	and	and	CC
cord-263862-zzys31e9	215	34	B	B	NNP
cord-263862-zzys31e9	215	35	)	)	-RRB-
cord-263862-zzys31e9	215	36	.	.	.
cord-263862-zzys31e9	216	1	CXCL16	CXCL16	NNP
cord-263862-zzys31e9	217	1	secretion	secretion	NN
cord-263862-zzys31e9	217	2	by	by	IN
cord-263862-zzys31e9	217	3	BMDC	BMDC	NNP
cord-263862-zzys31e9	217	4	was	be	VBD
cord-263862-zzys31e9	217	5	not	not	RB
cord-263862-zzys31e9	217	6	detected	detect	VBN
cord-263862-zzys31e9	217	7	in	in	IN
cord-263862-zzys31e9	217	8	response	response	NN
cord-263862-zzys31e9	217	9	to	to	IN
cord-263862-zzys31e9	217	10	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	217	11	(	(	-LRB-
cord-263862-zzys31e9	217	12	Fig	Fig	NNP
cord-263862-zzys31e9	217	13	.	.	.
cord-263862-zzys31e9	217	14	6C	6C	NNP
cord-263862-zzys31e9	217	15	)	)	-RRB-
cord-263862-zzys31e9	217	16	.	.	.
cord-263862-zzys31e9	218	1	In	in	IN
cord-263862-zzys31e9	218	2	order	order	NN
cord-263862-zzys31e9	218	3	to	to	TO
cord-263862-zzys31e9	218	4	reap	reap	VB
cord-263862-zzys31e9	218	5	the	the	DT
cord-263862-zzys31e9	218	6	optimum	optimum	JJ
cord-263862-zzys31e9	218	7	benefit	benefit	NN
cord-263862-zzys31e9	218	8	from	from	IN
cord-263862-zzys31e9	218	9	therapeutic	therapeutic	JJ
cord-263862-zzys31e9	218	10	immunisation	immunisation	NN
cord-263862-zzys31e9	218	11	strategies	strategy	NNS
cord-263862-zzys31e9	218	12	in	in	IN
cord-263862-zzys31e9	218	13	cancer	cancer	NN
cord-263862-zzys31e9	218	14	or	or	CC
cord-263862-zzys31e9	218	15	chronic	chronic	JJ
cord-263862-zzys31e9	218	16	viral	viral	JJ
cord-263862-zzys31e9	218	17	infections	infection	NNS
cord-263862-zzys31e9	218	18	,	,	,
cord-263862-zzys31e9	218	19	vaccines	vaccine	NNS
cord-263862-zzys31e9	218	20	will	will	MD
cord-263862-zzys31e9	218	21	need	need	VB
cord-263862-zzys31e9	218	22	to	to	TO
cord-263862-zzys31e9	218	23	be	be	VB
cord-263862-zzys31e9	218	24	formulated	formulate	VBN
cord-263862-zzys31e9	218	25	in	in	IN
cord-263862-zzys31e9	218	26	such	such	PDT
cord-263862-zzys31e9	218	27	a	a	DT
cord-263862-zzys31e9	218	28	way	way	NN
cord-263862-zzys31e9	218	29	as	as	IN
cord-263862-zzys31e9	218	30	to	to	TO
cord-263862-zzys31e9	218	31	augment	augment	VB
cord-263862-zzys31e9	218	32	the	the	DT
cord-263862-zzys31e9	218	33	Th1	th1	CD
cord-263862-zzys31e9	218	34	effector	effector	NN
cord-263862-zzys31e9	218	35	arm	arm	NN
cord-263862-zzys31e9	218	36	of	of	IN
cord-263862-zzys31e9	218	37	the	the	DT
cord-263862-zzys31e9	218	38	immune	immune	JJ
cord-263862-zzys31e9	218	39	response	response	NN
cord-263862-zzys31e9	218	40	.	.	.
cord-263862-zzys31e9	219	1	In	in	IN
cord-263862-zzys31e9	219	2	this	this	DT
cord-263862-zzys31e9	219	3	report	report	NN
cord-263862-zzys31e9	219	4	,	,	,
cord-263862-zzys31e9	219	5	we	-PRON-	PRP
cord-263862-zzys31e9	219	6	show	show	VBP
cord-263862-zzys31e9	219	7	that	that	IN
cord-263862-zzys31e9	219	8	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	219	9	can	can	MD
cord-263862-zzys31e9	219	10	act	act	VB
cord-263862-zzys31e9	219	11	as	as	IN
cord-263862-zzys31e9	219	12	a	a	DT
cord-263862-zzys31e9	219	13	Th1	th1	NN
cord-263862-zzys31e9	219	14	polarizing	polarize	VBG
cord-263862-zzys31e9	219	15	adjuvant	adjuvant	NN
cord-263862-zzys31e9	219	16	in	in	IN
cord-263862-zzys31e9	219	17	a	a	DT
cord-263862-zzys31e9	219	18	mouse	mouse	NN
cord-263862-zzys31e9	219	19	model	model	NN
cord-263862-zzys31e9	219	20	(	(	-LRB-
cord-263862-zzys31e9	219	21	Fig	fig	NN
cord-263862-zzys31e9	219	22	.	.	.
cord-263862-zzys31e9	219	23	1	1	CD
cord-263862-zzys31e9	219	24	G	g	NN
cord-263862-zzys31e9	219	25	)	)	-RRB-
cord-263862-zzys31e9	219	26	.	.	.
cord-263862-zzys31e9	220	1	We	-PRON-	PRP
cord-263862-zzys31e9	220	2	show	show	VBP
cord-263862-zzys31e9	220	3	that	that	IN
cord-263862-zzys31e9	220	4	bioactive	bioactive	JJ
cord-263862-zzys31e9	220	5	IFN-	IFN-	NNP
cord-263862-zzys31e9	220	6	␥	␥	CD
cord-263862-zzys31e9	220	7	but	but	CC
cord-263862-zzys31e9	220	8	not	not	RB
cord-263862-zzys31e9	220	9	IFN-	IFN-	NNP
cord-263862-zzys31e9	220	10	␣	␣	NN
cord-263862-zzys31e9	220	11	is	be	VBZ
cord-263862-zzys31e9	220	12	crucial	crucial	JJ
cord-263862-zzys31e9	220	13	for	for	IN
cord-263862-zzys31e9	220	14	this	this	DT
cord-263862-zzys31e9	220	15	adjuvant	adjuvant	JJ
cord-263862-zzys31e9	220	16	effect	effect	NN
cord-263862-zzys31e9	220	17	,	,	,
cord-263862-zzys31e9	220	18	as	as	IN
cord-263862-zzys31e9	220	19	antigenspecific	antigenspecific	NNP
cord-263862-zzys31e9	220	20	IgG2a	IgG2a	NNP
cord-263862-zzys31e9	220	21	responses	response	NNS
cord-263862-zzys31e9	220	22	to	to	TO
cord-263862-zzys31e9	220	23	co	co	VB
cord-263862-zzys31e9	220	24	-	-	JJ
cord-263862-zzys31e9	220	25	injected	inject	VBN
cord-263862-zzys31e9	220	26	protein	protein	NN
cord-263862-zzys31e9	220	27	are	be	VBP
cord-263862-zzys31e9	220	28	enhanced	enhance	VBN
cord-263862-zzys31e9	220	29	in	in	IN
cord-263862-zzys31e9	220	30	IFN-	IFN-	NNP
cord-263862-zzys31e9	221	1	␣	␣	NNP
cord-263862-zzys31e9	221	2	R	R	NNP
cord-263862-zzys31e9	221	3	−/−	−/−	NNP
cord-263862-zzys31e9	221	4	mice	mouse	NNS
cord-263862-zzys31e9	221	5	but	but	CC
cord-263862-zzys31e9	221	6	not	not	RB
cord-263862-zzys31e9	222	1	IFN-	IFN-	NNP
cord-263862-zzys31e9	222	2	␥	␥	CD
cord-263862-zzys31e9	222	3	R	r	NN
cord-263862-zzys31e9	223	1	−/−	−/−	NNP
cord-263862-zzys31e9	223	2	mice	mouse	NNS
cord-263862-zzys31e9	223	3	(	(	-LRB-
cord-263862-zzys31e9	223	4	Fig	Fig	NNP
cord-263862-zzys31e9	223	5	.	.	.
cord-263862-zzys31e9	223	6	3C	3C	NNP
cord-263862-zzys31e9	223	7	)	)	-RRB-
cord-263862-zzys31e9	223	8	.	.	.
cord-263862-zzys31e9	224	1	Immuno	immuno	JJ
cord-263862-zzys31e9	224	2	-	-	HYPH
cord-263862-zzys31e9	224	3	depletion	depletion	NN
cord-263862-zzys31e9	224	4	of	of	IN
cord-263862-zzys31e9	224	5	NK	NK	NNP
cord-263862-zzys31e9	224	6	cells	cell	NNS
cord-263862-zzys31e9	224	7	revealed	reveal	VBD
cord-263862-zzys31e9	224	8	that	that	IN
cord-263862-zzys31e9	224	9	they	-PRON-	PRP
cord-263862-zzys31e9	224	10	are	be	VBP
cord-263862-zzys31e9	224	11	an	an	DT
cord-263862-zzys31e9	224	12	important	important	JJ
cord-263862-zzys31e9	224	13	source	source	NN
cord-263862-zzys31e9	224	14	of	of	IN
cord-263862-zzys31e9	224	15	the	the	DT
cord-263862-zzys31e9	224	16	innate	innate	JJ
cord-263862-zzys31e9	224	17	IFN-	IFN-	NNP
cord-263862-zzys31e9	224	18	␥	␥	NNP
cord-263862-zzys31e9	224	19	produced	produce	VBN
cord-263862-zzys31e9	224	20	in	in	IN
cord-263862-zzys31e9	224	21	response	response	NN
cord-263862-zzys31e9	224	22	to	to	IN
cord-263862-zzys31e9	224	23	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	224	24	injection	injection	NN
cord-263862-zzys31e9	224	25	in	in	IN
cord-263862-zzys31e9	224	26	vivo	vivo	FW
cord-263862-zzys31e9	224	27	(	(	-LRB-
cord-263862-zzys31e9	224	28	Fig	Fig	NNP
cord-263862-zzys31e9	224	29	.	.	.
cord-263862-zzys31e9	224	30	4A	4a	CD
cord-263862-zzys31e9	224	31	)	)	-RRB-
cord-263862-zzys31e9	224	32	.	.	.
cord-263862-zzys31e9	225	1	Furthermore	furthermore	RB
cord-263862-zzys31e9	225	2	,	,	,
cord-263862-zzys31e9	225	3	we	-PRON-	PRP
cord-263862-zzys31e9	225	4	show	show	VBP
cord-263862-zzys31e9	225	5	that	that	IN
cord-263862-zzys31e9	225	6	stimulation	stimulation	NN
cord-263862-zzys31e9	225	7	of	of	IN
cord-263862-zzys31e9	225	8	murine	murine	JJ
cord-263862-zzys31e9	225	9	BMDCs	bmdc	NNS
cord-263862-zzys31e9	225	10	with	with	IN
cord-263862-zzys31e9	225	11	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	225	12	in	in	IN
cord-263862-zzys31e9	225	13	vitro	vitro	FW
cord-263862-zzys31e9	225	14	can	can	MD
cord-263862-zzys31e9	225	15	induce	induce	VB
cord-263862-zzys31e9	225	16	DC	DC	NNP
cord-263862-zzys31e9	225	17	maturation	maturation	NN
cord-263862-zzys31e9	225	18	(	(	-LRB-
cord-263862-zzys31e9	225	19	Fig	Fig	NNP
cord-263862-zzys31e9	225	20	.	.	.
cord-263862-zzys31e9	225	21	5A	5a	CD
cord-263862-zzys31e9	225	22	-	-	HYPH
cord-263862-zzys31e9	225	23	C	C	NNP
cord-263862-zzys31e9	225	24	)	)	-RRB-
cord-263862-zzys31e9	225	25	and	and	CC
cord-263862-zzys31e9	225	26	chemokine	chemokine	NN
cord-263862-zzys31e9	225	27	secretion	secretion	NN
cord-263862-zzys31e9	225	28	(	(	-LRB-
cord-263862-zzys31e9	225	29	particularly	particularly	RB
cord-263862-zzys31e9	225	30	CXCL10	CXCL10	NNP
cord-263862-zzys31e9	225	31	and	and	CC
cord-263862-zzys31e9	225	32	CCL2	CCL2	NNP
cord-263862-zzys31e9	225	33	,	,	,
cord-263862-zzys31e9	225	34	Fig	Fig	NNP
cord-263862-zzys31e9	225	35	.	.	.
cord-263862-zzys31e9	225	36	6A	6a	NN
cord-263862-zzys31e9	225	37	and	and	CC
cord-263862-zzys31e9	225	38	B	B	NNP
cord-263862-zzys31e9	225	39	)	)	-RRB-
cord-263862-zzys31e9	225	40	.	.	.
cord-263862-zzys31e9	226	1	Additionally	additionally	RB
cord-263862-zzys31e9	226	2	,	,	,
cord-263862-zzys31e9	226	3	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	226	4	injection	injection	NN
cord-263862-zzys31e9	226	5	resulted	result	VBD
cord-263862-zzys31e9	226	6	in	in	IN
cord-263862-zzys31e9	226	7	an	an	DT
cord-263862-zzys31e9	226	8	enlargement	enlargement	NN
cord-263862-zzys31e9	226	9	of	of	IN
cord-263862-zzys31e9	226	10	the	the	DT
cord-263862-zzys31e9	226	11	local	local	JJ
cord-263862-zzys31e9	226	12	draining	drain	VBG
cord-263862-zzys31e9	226	13	lymph	lymph	NN
cord-263862-zzys31e9	226	14	node	node	NN
cord-263862-zzys31e9	226	15	(	(	-LRB-
cord-263862-zzys31e9	226	16	popliteal	popliteal	NNP
cord-263862-zzys31e9	226	17	)	)	-RRB-
cord-263862-zzys31e9	226	18	following	follow	VBG
cord-263862-zzys31e9	226	19	i.m	i.m	NNP
cord-263862-zzys31e9	226	20	.	.	NNP
cord-263862-zzys31e9	226	21	injection	injection	NN
cord-263862-zzys31e9	226	22	(	(	-LRB-
cord-263862-zzys31e9	226	23	data	datum	NNS
cord-263862-zzys31e9	226	24	not	not	RB
cord-263862-zzys31e9	226	25	shown	show	VBN
cord-263862-zzys31e9	226	26	)	)	-RRB-
cord-263862-zzys31e9	226	27	.	.	.
cord-263862-zzys31e9	227	1	Therefore	therefore	RB
cord-263862-zzys31e9	227	2	,	,	,
cord-263862-zzys31e9	227	3	we	-PRON-	PRP
cord-263862-zzys31e9	227	4	can	can	MD
cord-263862-zzys31e9	227	5	conclude	conclude	VB
cord-263862-zzys31e9	227	6	that	that	IN
cord-263862-zzys31e9	227	7	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	227	8	injection	injection	NN
cord-263862-zzys31e9	227	9	activates	activate	VBZ
cord-263862-zzys31e9	227	10	the	the	DT
cord-263862-zzys31e9	227	11	innate	innate	JJ
cord-263862-zzys31e9	227	12	immune	immune	JJ
cord-263862-zzys31e9	227	13	response	response	NN
cord-263862-zzys31e9	227	14	enhancing	enhance	VBG
cord-263862-zzys31e9	227	15	the	the	DT
cord-263862-zzys31e9	227	16	induction	induction	NN
cord-263862-zzys31e9	227	17	of	of	IN
cord-263862-zzys31e9	227	18	Th1	Th1	NNP
cord-263862-zzys31e9	227	19	responses	response	NNS
cord-263862-zzys31e9	227	20	to	to	TO
cord-263862-zzys31e9	227	21	co	co	VB
cord-263862-zzys31e9	227	22	-	-	JJ
cord-263862-zzys31e9	227	23	injected	inject	VBN
cord-263862-zzys31e9	227	24	antigen	antigen	NN
cord-263862-zzys31e9	227	25	.	.	.
cord-263862-zzys31e9	228	1	The	the	DT
cord-263862-zzys31e9	228	2	recombinant	recombinant	JJ
cord-263862-zzys31e9	228	3	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	228	4	(	(	-LRB-
cord-263862-zzys31e9	228	5	vCP1452	vcp1452	NN
cord-263862-zzys31e9	228	6	)	)	-RRB-
cord-263862-zzys31e9	228	7	that	that	IN
cord-263862-zzys31e9	228	8	we	-PRON-	PRP
cord-263862-zzys31e9	228	9	use	use	VBP
cord-263862-zzys31e9	228	10	in	in	IN
cord-263862-zzys31e9	228	11	this	this	DT
cord-263862-zzys31e9	228	12	study	study	NN
cord-263862-zzys31e9	228	13	has	have	VBZ
cord-263862-zzys31e9	228	14	been	be	VBN
cord-263862-zzys31e9	228	15	shown	show	VBN
cord-263862-zzys31e9	228	16	to	to	TO
cord-263862-zzys31e9	228	17	be	be	VB
cord-263862-zzys31e9	228	18	well	well	RB
cord-263862-zzys31e9	228	19	tolerated	tolerate	VBN
cord-263862-zzys31e9	228	20	in	in	IN
cord-263862-zzys31e9	228	21	clinical	clinical	JJ
cord-263862-zzys31e9	228	22	trials	trial	NNS
cord-263862-zzys31e9	228	23	[	[	-LRB-
cord-263862-zzys31e9	228	24	15	15	CD
cord-263862-zzys31e9	228	25	]	]	-RRB-
cord-263862-zzys31e9	228	26	.	.	.
cord-263862-zzys31e9	229	1	Previous	previous	JJ
cord-263862-zzys31e9	229	2	reports	report	NNS
cord-263862-zzys31e9	229	3	have	have	VBP
cord-263862-zzys31e9	229	4	shown	show	VBN
cord-263862-zzys31e9	229	5	that	that	IN
cord-263862-zzys31e9	229	6	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	229	7	can	can	MD
cord-263862-zzys31e9	229	8	act	act	VB
cord-263862-zzys31e9	229	9	as	as	IN
cord-263862-zzys31e9	229	10	an	an	DT
cord-263862-zzys31e9	229	11	adjuvant	adjuvant	NN
cord-263862-zzys31e9	229	12	[	[	-LRB-
cord-263862-zzys31e9	229	13	7	7	CD
cord-263862-zzys31e9	229	14	,	,	,
cord-263862-zzys31e9	229	15	8	8	CD
cord-263862-zzys31e9	229	16	]	]	-RRB-
cord-263862-zzys31e9	229	17	.	.	.
cord-263862-zzys31e9	230	1	In	in	IN
cord-263862-zzys31e9	230	2	particular	particular	JJ
cord-263862-zzys31e9	230	3	,	,	,
cord-263862-zzys31e9	230	4	Boudet	Boudet	NNP
cord-263862-zzys31e9	230	5	et	et	NNP
cord-263862-zzys31e9	230	6	al	al	NNP
cord-263862-zzys31e9	230	7	.	.	.
cord-263862-zzys31e9	231	1	[	[	-LRB-
cord-263862-zzys31e9	231	2	7	7	CD
cord-263862-zzys31e9	231	3	]	]	-RRB-
cord-263862-zzys31e9	231	4	showed	show	VBD
cord-263862-zzys31e9	231	5	that	that	IN
cord-263862-zzys31e9	231	6	purified	purify	VBN
cord-263862-zzys31e9	231	7	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	231	8	in	in	IN
cord-263862-zzys31e9	231	9	either	either	CC
cord-263862-zzys31e9	231	10	an	an	DT
cord-263862-zzys31e9	231	11	infectious	infectious	JJ
cord-263862-zzys31e9	231	12	or	or	CC
cord-263862-zzys31e9	231	13	non	non	JJ
cord-263862-zzys31e9	231	14	-	-	JJ
cord-263862-zzys31e9	231	15	infectious	infectious	JJ
cord-263862-zzys31e9	231	16	form	form	NN
cord-263862-zzys31e9	231	17	had	have	VBD
cord-263862-zzys31e9	231	18	an	an	DT
cord-263862-zzys31e9	231	19	adjuvant	adjuvant	JJ
cord-263862-zzys31e9	231	20	effect	effect	NN
cord-263862-zzys31e9	231	21	when	when	WRB
cord-263862-zzys31e9	231	22	co	co	NN
cord-263862-zzys31e9	231	23	-	-	VBN
cord-263862-zzys31e9	231	24	administered	administer	VBN
cord-263862-zzys31e9	231	25	with	with	IN
cord-263862-zzys31e9	231	26	the	the	DT
cord-263862-zzys31e9	231	27	recombinant	recombinant	JJ
cord-263862-zzys31e9	231	28	HIV	HIV	NNP
cord-263862-zzys31e9	231	29	antigen	antigen	NN
cord-263862-zzys31e9	231	30	,	,	,
cord-263862-zzys31e9	231	31	gp160	gp160	NNP
cord-263862-zzys31e9	231	32	;	;	:
cord-263862-zzys31e9	231	33	resulting	result	VBG
cord-263862-zzys31e9	231	34	in	in	IN
cord-263862-zzys31e9	231	35	an	an	DT
cord-263862-zzys31e9	231	36	increase	increase	NN
cord-263862-zzys31e9	231	37	of	of	IN
cord-263862-zzys31e9	231	38	antigen	antigen	NN
cord-263862-zzys31e9	231	39	-	-	HYPH
cord-263862-zzys31e9	231	40	specific	specific	JJ
cord-263862-zzys31e9	231	41	IgG	igg	NN
cord-263862-zzys31e9	231	42	in	in	IN
cord-263862-zzys31e9	231	43	both	both	DT
cord-263862-zzys31e9	231	44	mice	mouse	NNS
cord-263862-zzys31e9	231	45	and	and	CC
cord-263862-zzys31e9	231	46	guinea	guinea	NN
cord-263862-zzys31e9	231	47	pigs	pig	NNS
cord-263862-zzys31e9	231	48	.	.	.
cord-263862-zzys31e9	232	1	Hutchings	Hutchings	NNP
cord-263862-zzys31e9	232	2	et	et	NNP
cord-263862-zzys31e9	232	3	al	al	NNP
cord-263862-zzys31e9	232	4	.	.	.
cord-263862-zzys31e9	233	1	[	[	-LRB-
cord-263862-zzys31e9	233	2	8	8	CD
cord-263862-zzys31e9	233	3	]	]	-RRB-
cord-263862-zzys31e9	233	4	furthered	further	VBD
cord-263862-zzys31e9	233	5	this	this	DT
cord-263862-zzys31e9	233	6	by	by	IN
cord-263862-zzys31e9	233	7	showing	show	VBG
cord-263862-zzys31e9	233	8	that	that	IN
cord-263862-zzys31e9	233	9	this	this	DT
cord-263862-zzys31e9	233	10	adjuvant	adjuvant	JJ
cord-263862-zzys31e9	233	11	activity	activity	NN
cord-263862-zzys31e9	233	12	was	be	VBD
cord-263862-zzys31e9	233	13	common	common	JJ
cord-263862-zzys31e9	233	14	to	to	IN
cord-263862-zzys31e9	233	15	other	other	JJ
cord-263862-zzys31e9	233	16	poxviruses	poxvirus	NNS
cord-263862-zzys31e9	233	17	(	(	-LRB-
cord-263862-zzys31e9	233	18	NYVAC	NYVAC	NNP
cord-263862-zzys31e9	233	19	,	,	,
cord-263862-zzys31e9	233	20	fowlpox	fowlpox	NNP
cord-263862-zzys31e9	233	21	(	(	-LRB-
cord-263862-zzys31e9	233	22	FP9	FP9	NNP
cord-263862-zzys31e9	233	23	)	)	-RRB-
cord-263862-zzys31e9	233	24	,	,	,
cord-263862-zzys31e9	233	25	as	as	RB
cord-263862-zzys31e9	233	26	well	well	RB
cord-263862-zzys31e9	233	27	as	as	IN
cord-263862-zzys31e9	233	28	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	233	29	)	)	-RRB-
cord-263862-zzys31e9	233	30	.	.	.
cord-263862-zzys31e9	234	1	The	the	DT
cord-263862-zzys31e9	234	2	poxviruses	poxvirus	NNS
cord-263862-zzys31e9	234	3	:	:	:
cord-263862-zzys31e9	234	4	NYVAC	NYVAC	NNP
cord-263862-zzys31e9	234	5	,	,	,
cord-263862-zzys31e9	234	6	fowlpox	fowlpox	NNP
cord-263862-zzys31e9	234	7	(	(	-LRB-
cord-263862-zzys31e9	234	8	FP9	FP9	NNP
cord-263862-zzys31e9	234	9	)	)	-RRB-
cord-263862-zzys31e9	234	10	,	,	,
cord-263862-zzys31e9	234	11	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	234	12	and	and	CC
cord-263862-zzys31e9	234	13	to	to	IN
cord-263862-zzys31e9	234	14	a	a	DT
cord-263862-zzys31e9	234	15	lesser	less	JJR
cord-263862-zzys31e9	234	16	extent	extent	NN
cord-263862-zzys31e9	234	17	,	,	,
cord-263862-zzys31e9	234	18	adenovirus	adenovirus	NN
cord-263862-zzys31e9	234	19	all	all	DT
cord-263862-zzys31e9	234	20	enhanced	enhance	VBD
cord-263862-zzys31e9	234	21	the	the	DT
cord-263862-zzys31e9	234	22	immune	immune	JJ
cord-263862-zzys31e9	234	23	response	response	NN
cord-263862-zzys31e9	234	24	to	to	TO
cord-263862-zzys31e9	234	25	co	co	VB
cord-263862-zzys31e9	234	26	-	-	JJ
cord-263862-zzys31e9	234	27	injected	inject	VBN
cord-263862-zzys31e9	234	28	recombinant	recombinant	JJ
cord-263862-zzys31e9	234	29	Hepatitis	Hepatitis	NNP
cord-263862-zzys31e9	234	30	B	B	NNP
cord-263862-zzys31e9	234	31	surface	surface	NN
cord-263862-zzys31e9	234	32	antigen	antigen	NN
cord-263862-zzys31e9	234	33	(	(	-LRB-
cord-263862-zzys31e9	234	34	HBsAg	hbsag	ADD
cord-263862-zzys31e9	234	35	)	)	-RRB-
cord-263862-zzys31e9	234	36	[	[	-LRB-
cord-263862-zzys31e9	234	37	8	8	CD
cord-263862-zzys31e9	234	38	]	]	-RRB-
cord-263862-zzys31e9	234	39	.	.	.
cord-263862-zzys31e9	235	1	Interestingly	interestingly	RB
cord-263862-zzys31e9	235	2	,	,	,
cord-263862-zzys31e9	235	3	the	the	DT
cord-263862-zzys31e9	235	4	combination	combination	NN
cord-263862-zzys31e9	235	5	of	of	IN
cord-263862-zzys31e9	235	6	the	the	DT
cord-263862-zzys31e9	235	7	non	non	JJ
cord-263862-zzys31e9	235	8	-	-	JJ
cord-263862-zzys31e9	235	9	recombinant	recombinant	JJ
cord-263862-zzys31e9	235	10	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	235	11	vector	vector	NN
cord-263862-zzys31e9	235	12	with	with	IN
cord-263862-zzys31e9	235	13	HBsAg	hbsag	ADD
cord-263862-zzys31e9	235	14	induced	induce	VBD
cord-263862-zzys31e9	235	15	the	the	DT
cord-263862-zzys31e9	235	16	strongest	strong	JJS
cord-263862-zzys31e9	235	17	antigen	antigen	NN
cord-263862-zzys31e9	235	18	-	-	HYPH
cord-263862-zzys31e9	235	19	specific	specific	JJ
cord-263862-zzys31e9	235	20	cellular	cellular	JJ
cord-263862-zzys31e9	235	21	response	response	NN
cord-263862-zzys31e9	235	22	in	in	IN
cord-263862-zzys31e9	235	23	the	the	DT
cord-263862-zzys31e9	235	24	draining	drain	VBG
cord-263862-zzys31e9	235	25	lymph	lymph	NN
cord-263862-zzys31e9	235	26	node	node	NN
cord-263862-zzys31e9	235	27	compared	compare	VBN
cord-263862-zzys31e9	235	28	to	to	IN
cord-263862-zzys31e9	235	29	the	the	DT
cord-263862-zzys31e9	235	30	responses	response	NNS
cord-263862-zzys31e9	235	31	resulting	result	VBG
cord-263862-zzys31e9	235	32	from	from	IN
cord-263862-zzys31e9	235	33	including	include	VBG
cord-263862-zzys31e9	235	34	the	the	DT
cord-263862-zzys31e9	235	35	other	other	JJ
cord-263862-zzys31e9	235	36	poxvirus	poxvirus	NNP
cord-263862-zzys31e9	235	37	vectors	vector	NNS
cord-263862-zzys31e9	235	38	investigated	investigate	VBD
cord-263862-zzys31e9	235	39	[	[	-LRB-
cord-263862-zzys31e9	235	40	8	8	CD
cord-263862-zzys31e9	235	41	]	]	-RRB-
cord-263862-zzys31e9	235	42	.	.	.
cord-263862-zzys31e9	236	1	Two	two	CD
cord-263862-zzys31e9	236	2	major	major	JJ
cord-263862-zzys31e9	236	3	TLR	TLR	NNP
cord-263862-zzys31e9	236	4	mediated	mediate	VBD
cord-263862-zzys31e9	236	5	signalling	signal	VBG
cord-263862-zzys31e9	236	6	pathways	pathway	NNS
cord-263862-zzys31e9	236	7	participate	participate	VBP
cord-263862-zzys31e9	236	8	in	in	IN
cord-263862-zzys31e9	236	9	the	the	DT
cord-263862-zzys31e9	236	10	response	response	NN
cord-263862-zzys31e9	236	11	to	to	IN
cord-263862-zzys31e9	236	12	pathogens	pathogen	NNS
cord-263862-zzys31e9	236	13	,	,	,
cord-263862-zzys31e9	236	14	the	the	DT
cord-263862-zzys31e9	236	15	nuclear	nuclear	JJ
cord-263862-zzys31e9	236	16	-	-	HYPH
cord-263862-zzys31e9	236	17	factor	factor	NN
cord-263862-zzys31e9	236	18	B	b	NN
cord-263862-zzys31e9	236	19	(	(	-LRB-
cord-263862-zzys31e9	236	20	NF	NF	NNP
cord-263862-zzys31e9	236	21	-	-	HYPH
cord-263862-zzys31e9	236	22	B)-dependent	B)-dependent	NNP
cord-263862-zzys31e9	236	23	pathway	pathway	NN
cord-263862-zzys31e9	236	24	leading	lead	VBG
cord-263862-zzys31e9	236	25	to	to	IN
cord-263862-zzys31e9	236	26	the	the	DT
cord-263862-zzys31e9	236	27	secretion	secretion	NN
cord-263862-zzys31e9	236	28	of	of	IN
cord-263862-zzys31e9	236	29	IL-12	IL-12	NNP
cord-263862-zzys31e9	236	30	and	and	CC
cord-263862-zzys31e9	236	31	other	other	JJ
cord-263862-zzys31e9	236	32	inflammatory	inflammatory	JJ
cord-263862-zzys31e9	236	33	cytokines	cytokine	NNS
cord-263862-zzys31e9	236	34	and	and	CC
cord-263862-zzys31e9	236	35	the	the	DT
cord-263862-zzys31e9	236	36	type	type	NN
cord-263862-zzys31e9	236	37	I	-PRON-	PRP
cord-263862-zzys31e9	236	38	IFN	IFN	NNP
cord-263862-zzys31e9	236	39	pathway	pathway	NN
cord-263862-zzys31e9	236	40	which	which	WDT
cord-263862-zzys31e9	236	41	synergises	synergise	VBZ
cord-263862-zzys31e9	236	42	with	with	IN
cord-263862-zzys31e9	236	43	the	the	DT
cord-263862-zzys31e9	236	44	NF	nf	NN
cord-263862-zzys31e9	236	45	-	-	HYPH
cord-263862-zzys31e9	236	46	B	b	NN
cord-263862-zzys31e9	236	47	pathway	pathway	NN
cord-263862-zzys31e9	236	48	for	for	IN
cord-263862-zzys31e9	236	49	optimal	optimal	JJ
cord-263862-zzys31e9	236	50	IL-12p70	il-12p70	CD
cord-263862-zzys31e9	236	51	secretion	secretion	NN
cord-263862-zzys31e9	236	52	[	[	-LRB-
cord-263862-zzys31e9	236	53	13	13	CD
cord-263862-zzys31e9	236	54	]	]	-RRB-
cord-263862-zzys31e9	236	55	.	.	.
cord-263862-zzys31e9	237	1	We	-PRON-	PRP
cord-263862-zzys31e9	237	2	show	show	VBP
cord-263862-zzys31e9	237	3	that	that	IN
cord-263862-zzys31e9	237	4	injection	injection	NN
cord-263862-zzys31e9	237	5	of	of	IN
cord-263862-zzys31e9	237	6	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	237	7	results	result	VBZ
cord-263862-zzys31e9	237	8	in	in	IN
cord-263862-zzys31e9	237	9	an	an	DT
cord-263862-zzys31e9	237	10	increase	increase	NN
cord-263862-zzys31e9	237	11	in	in	IN
cord-263862-zzys31e9	237	12	the	the	DT
cord-263862-zzys31e9	237	13	levels	level	NNS
cord-263862-zzys31e9	237	14	of	of	IN
cord-263862-zzys31e9	237	15	both	both	DT
cord-263862-zzys31e9	237	16	circulating	circulate	VBG
cord-263862-zzys31e9	238	1	IFN-	IFN-	NNP
cord-263862-zzys31e9	238	2	␣	␣	NN
cord-263862-zzys31e9	238	3	and	and	CC
cord-263862-zzys31e9	239	1	IFN-	IFN-	NNP
cord-263862-zzys31e9	239	2	␥	␥	NNP
cord-263862-zzys31e9	239	3	(	(	-LRB-
cord-263862-zzys31e9	239	4	Fig	Fig	NNP
cord-263862-zzys31e9	239	5	.	.	.
cord-263862-zzys31e9	239	6	2A	2a	NN
cord-263862-zzys31e9	239	7	and	and	CC
cord-263862-zzys31e9	239	8	B	B	NNP
cord-263862-zzys31e9	239	9	)	)	-RRB-
cord-263862-zzys31e9	239	10	.	.	.
cord-263862-zzys31e9	240	1	In	in	IN
cord-263862-zzys31e9	240	2	order	order	NN
cord-263862-zzys31e9	240	3	to	to	TO
cord-263862-zzys31e9	240	4	determine	determine	VB
cord-263862-zzys31e9	240	5	if	if	IN
cord-263862-zzys31e9	240	6	the	the	DT
cord-263862-zzys31e9	240	7	induction	induction	NN
cord-263862-zzys31e9	240	8	of	of	IN
cord-263862-zzys31e9	240	9	one	one	CD
cord-263862-zzys31e9	240	10	or	or	CC
cord-263862-zzys31e9	240	11	both	both	DT
cord-263862-zzys31e9	240	12	of	of	IN
cord-263862-zzys31e9	240	13	these	these	DT
cord-263862-zzys31e9	240	14	cytokines	cytokine	NNS
cord-263862-zzys31e9	240	15	was	be	VBD
cord-263862-zzys31e9	240	16	crucial	crucial	JJ
cord-263862-zzys31e9	240	17	for	for	IN
cord-263862-zzys31e9	240	18	the	the	DT
cord-263862-zzys31e9	240	19	adjuvant	adjuvant	JJ
cord-263862-zzys31e9	240	20	effect	effect	NN
cord-263862-zzys31e9	240	21	of	of	IN
cord-263862-zzys31e9	240	22	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	240	23	,	,	,
cord-263862-zzys31e9	240	24	we	-PRON-	PRP
cord-263862-zzys31e9	240	25	immunised	immunise	VBD
cord-263862-zzys31e9	240	26	wild	wild	JJ
cord-263862-zzys31e9	240	27	type	type	NN
cord-263862-zzys31e9	240	28	(	(	-LRB-
cord-263862-zzys31e9	240	29	129	129	CD
cord-263862-zzys31e9	240	30	/	/	SYM
cord-263862-zzys31e9	240	31	Sv	Sv	NNP
cord-263862-zzys31e9	240	32	)	)	-RRB-
cord-263862-zzys31e9	240	33	,	,	.
cord-263862-zzys31e9	241	1	IFN-	IFN-	NNP
cord-263862-zzys31e9	242	1	␣	␣	NNP
cord-263862-zzys31e9	242	2	R	R	NNP
cord-263862-zzys31e9	242	3	−/−	−/−	NNP
cord-263862-zzys31e9	242	4	and	and	CC
cord-263862-zzys31e9	242	5	IFN-	IFN-	NNP
cord-263862-zzys31e9	243	1	␥	␥	NNP
cord-263862-zzys31e9	243	2	R	R	NNP
cord-263862-zzys31e9	243	3	−/−	−/−	NNP
cord-263862-zzys31e9	243	4	mice	mouse	NNS
cord-263862-zzys31e9	243	5	with	with	IN
cord-263862-zzys31e9	243	6	gB	gB	NNP
cord-263862-zzys31e9	243	7	(	(	-LRB-
cord-263862-zzys31e9	243	8	CMV	CMV	NNP
cord-263862-zzys31e9	243	9	)	)	-RRB-
cord-263862-zzys31e9	243	10	either	either	CC
cord-263862-zzys31e9	243	11	with	with	IN
cord-263862-zzys31e9	243	12	or	or	CC
cord-263862-zzys31e9	243	13	without	without	IN
cord-263862-zzys31e9	243	14	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	243	15	.	.	.
cord-263862-zzys31e9	244	1	Both	both	DT
cord-263862-zzys31e9	244	2	the	the	DT
cord-263862-zzys31e9	244	3	129	129	CD
cord-263862-zzys31e9	244	4	/	/	SYM
cord-263862-zzys31e9	244	5	Sv	Sv	NNP
cord-263862-zzys31e9	244	6	and	and	CC
cord-263862-zzys31e9	244	7	IFN-	IFN-	NNP
cord-263862-zzys31e9	245	1	␣	␣	NNP
cord-263862-zzys31e9	245	2	R	R	NNP
cord-263862-zzys31e9	245	3	−/−	−/−	NNP
cord-263862-zzys31e9	245	4	mice	mouse	NNS
cord-263862-zzys31e9	245	5	that	that	WDT
cord-263862-zzys31e9	245	6	received	receive	VBD
cord-263862-zzys31e9	245	7	gB	gB	NNP
cord-263862-zzys31e9	245	8	and	and	CC
cord-263862-zzys31e9	245	9	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	245	10	produced	produce	VBD
cord-263862-zzys31e9	245	11	higher	high	JJR
cord-263862-zzys31e9	245	12	titres	titre	NNS
cord-263862-zzys31e9	245	13	of	of	IN
cord-263862-zzys31e9	245	14	gB	gB	NNP
cord-263862-zzys31e9	245	15	specific	specific	JJ
cord-263862-zzys31e9	245	16	IgG2a	IgG2a	NNP
cord-263862-zzys31e9	245	17	when	when	WRB
cord-263862-zzys31e9	245	18	compared	compare	VBN
cord-263862-zzys31e9	245	19	to	to	IN
cord-263862-zzys31e9	245	20	the	the	DT
cord-263862-zzys31e9	245	21	groups	group	NNS
cord-263862-zzys31e9	245	22	that	that	WDT
cord-263862-zzys31e9	245	23	received	receive	VBD
cord-263862-zzys31e9	245	24	gB	gB	NNP
cord-263862-zzys31e9	245	25	and	and	CC
cord-263862-zzys31e9	245	26	Placebo	Placebo	NNP
cord-263862-zzys31e9	245	27	(	(	-LRB-
cord-263862-zzys31e9	245	28	Fig	Fig	NNP
cord-263862-zzys31e9	245	29	.	.	.
cord-263862-zzys31e9	245	30	3	3	CD
cord-263862-zzys31e9	245	31	)	)	-RRB-
cord-263862-zzys31e9	245	32	,	,	,
cord-263862-zzys31e9	245	33	indicating	indicate	VBG
cord-263862-zzys31e9	245	34	that	that	IN
cord-263862-zzys31e9	245	35	bioactive	bioactive	JJ
cord-263862-zzys31e9	245	36	IFN-	IFN-	NNP
cord-263862-zzys31e9	245	37	␣	␣	NNP
cord-263862-zzys31e9	245	38	is	be	VBZ
cord-263862-zzys31e9	245	39	dispensable	dispensable	JJ
cord-263862-zzys31e9	245	40	for	for	IN
cord-263862-zzys31e9	245	41	the	the	DT
cord-263862-zzys31e9	245	42	adjuvant	adjuvant	JJ
cord-263862-zzys31e9	245	43	effect	effect	NN
cord-263862-zzys31e9	245	44	of	of	IN
cord-263862-zzys31e9	245	45	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	245	46	.	.	.
cord-263862-zzys31e9	246	1	A	a	DT
cord-263862-zzys31e9	246	2	study	study	NN
cord-263862-zzys31e9	246	3	investigating	investigate	VBG
cord-263862-zzys31e9	246	4	the	the	DT
cord-263862-zzys31e9	246	5	immunogenicity	immunogenicity	NN
cord-263862-zzys31e9	246	6	of	of	IN
cord-263862-zzys31e9	246	7	adenovirus	adenovirus	NN
cord-263862-zzys31e9	246	8	vectors	vector	NNS
cord-263862-zzys31e9	246	9	demonstrated	demonstrate	VBD
cord-263862-zzys31e9	246	10	that	that	IN
cord-263862-zzys31e9	246	11	although	although	IN
cord-263862-zzys31e9	246	12	type	type	NN
cord-263862-zzys31e9	246	13	I	-PRON-	PRP
cord-263862-zzys31e9	246	14	IFN	IFN	NNP
cord-263862-zzys31e9	246	15	signalling	signal	VBG
cord-263862-zzys31e9	246	16	is	be	VBZ
cord-263862-zzys31e9	246	17	an	an	DT
cord-263862-zzys31e9	246	18	important	important	JJ
cord-263862-zzys31e9	246	19	component	component	NN
cord-263862-zzys31e9	246	20	of	of	IN
cord-263862-zzys31e9	246	21	adenovirus	adenovirus	NN
cord-263862-zzys31e9	246	22	-	-	HYPH
cord-263862-zzys31e9	246	23	mediated	mediate	VBN
cord-263862-zzys31e9	246	24	DC	DC	NNP
cord-263862-zzys31e9	246	25	maturation	maturation	NN
cord-263862-zzys31e9	246	26	,	,	,
cord-263862-zzys31e9	246	27	it	-PRON-	PRP
cord-263862-zzys31e9	246	28	was	be	VBD
cord-263862-zzys31e9	246	29	dispensable	dispensable	JJ
cord-263862-zzys31e9	246	30	during	during	IN
cord-263862-zzys31e9	246	31	the	the	DT
cord-263862-zzys31e9	246	32	generation	generation	NN
cord-263862-zzys31e9	246	33	of	of	IN
cord-263862-zzys31e9	246	34	transgene	transgene	NN
cord-263862-zzys31e9	246	35	product	product	NN
cord-263862-zzys31e9	246	36	specific	specific	JJ
cord-263862-zzys31e9	246	37	CD8	CD8	NNP
cord-263862-zzys31e9	246	38	+	+	CC
cord-263862-zzys31e9	246	39	T	t	NN
cord-263862-zzys31e9	246	40	cell	cell	NN
cord-263862-zzys31e9	246	41	responses	response	NNS
cord-263862-zzys31e9	246	42	[	[	-LRB-
cord-263862-zzys31e9	246	43	16	16	CD
cord-263862-zzys31e9	246	44	]	]	-RRB-
cord-263862-zzys31e9	246	45	.	.	.
cord-263862-zzys31e9	247	1	Therefore	therefore	RB
cord-263862-zzys31e9	247	2	,	,	,
cord-263862-zzys31e9	247	3	it	-PRON-	PRP
cord-263862-zzys31e9	247	4	appears	appear	VBZ
cord-263862-zzys31e9	247	5	that	that	IN
cord-263862-zzys31e9	247	6	although	although	IN
cord-263862-zzys31e9	247	7	IFN-	IFN-	NNP
cord-263862-zzys31e9	247	8	␣	␣	NNP
cord-263862-zzys31e9	247	9	is	be	VBZ
cord-263862-zzys31e9	247	10	induced	induce	VBN
cord-263862-zzys31e9	247	11	by	by	IN
cord-263862-zzys31e9	247	12	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	247	13	and	and	CC
cord-263862-zzys31e9	247	14	may	may	MD
cord-263862-zzys31e9	247	15	well	well	RB
cord-263862-zzys31e9	247	16	play	play	VB
cord-263862-zzys31e9	247	17	a	a	DT
cord-263862-zzys31e9	247	18	role	role	NN
cord-263862-zzys31e9	247	19	in	in	IN
cord-263862-zzys31e9	247	20	augmenting	augment	VBG
cord-263862-zzys31e9	247	21	the	the	DT
cord-263862-zzys31e9	247	22	innate	innate	JJ
cord-263862-zzys31e9	247	23	immune	immune	JJ
cord-263862-zzys31e9	247	24	response	response	NN
cord-263862-zzys31e9	247	25	,	,	,
cord-263862-zzys31e9	247	26	it	-PRON-	PRP
cord-263862-zzys31e9	247	27	is	be	VBZ
cord-263862-zzys31e9	247	28	not	not	RB
cord-263862-zzys31e9	247	29	required	require	VBN
cord-263862-zzys31e9	247	30	for	for	IN
cord-263862-zzys31e9	247	31	its	-PRON-	PRP$
cord-263862-zzys31e9	247	32	'	'	``
cord-263862-zzys31e9	247	33	adjuvant	adjuvant	JJ
cord-263862-zzys31e9	247	34	effect	effect	NN
cord-263862-zzys31e9	247	35	.	.	.
cord-263862-zzys31e9	248	1	Activated	activate	VBN
cord-263862-zzys31e9	248	2	NK	NK	NNP
cord-263862-zzys31e9	248	3	cells	cell	NNS
cord-263862-zzys31e9	248	4	can	can	MD
cord-263862-zzys31e9	248	5	secrete	secrete	VB
cord-263862-zzys31e9	248	6	large	large	JJ
cord-263862-zzys31e9	248	7	amounts	amount	NNS
cord-263862-zzys31e9	248	8	of	of	IN
cord-263862-zzys31e9	248	9	IFN-	IFN-	NNP
cord-263862-zzys31e9	248	10	␥	␥	NNP
cord-263862-zzys31e9	248	11	in	in	IN
cord-263862-zzys31e9	248	12	response	response	NN
cord-263862-zzys31e9	248	13	to	to	IN
cord-263862-zzys31e9	248	14	pathogens	pathogen	NNS
cord-263862-zzys31e9	248	15	or	or	CC
cord-263862-zzys31e9	248	16	activated	activate	VBN
cord-263862-zzys31e9	248	17	DCs	DCs	NNP
cord-263862-zzys31e9	248	18	[	[	-LRB-
cord-263862-zzys31e9	248	19	17	17	CD
cord-263862-zzys31e9	248	20	]	]	-RRB-
cord-263862-zzys31e9	248	21	.	.	.
cord-263862-zzys31e9	249	1	In	in	IN
cord-263862-zzys31e9	249	2	order	order	NN
cord-263862-zzys31e9	249	3	to	to	TO
cord-263862-zzys31e9	249	4	determine	determine	VB
cord-263862-zzys31e9	249	5	if	if	IN
cord-263862-zzys31e9	249	6	the	the	DT
cord-263862-zzys31e9	249	7	IFN-	IFN-	NNP
cord-263862-zzys31e9	249	8	␥	␥	NNPS
cord-263862-zzys31e9	249	9	produced	produce	VBN
cord-263862-zzys31e9	249	10	in	in	IN
cord-263862-zzys31e9	249	11	response	response	NN
cord-263862-zzys31e9	249	12	to	to	IN
cord-263862-zzys31e9	249	13	immunisation	immunisation	NN
cord-263862-zzys31e9	249	14	with	with	IN
cord-263862-zzys31e9	249	15	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	249	16	(	(	-LRB-
cord-263862-zzys31e9	249	17	Fig	Fig	NNP
cord-263862-zzys31e9	249	18	.	.	.
cord-263862-zzys31e9	249	19	2A	2a	CD
cord-263862-zzys31e9	249	20	)	)	-RRB-
cord-263862-zzys31e9	249	21	was	be	VBD
cord-263862-zzys31e9	249	22	produced	produce	VBN
cord-263862-zzys31e9	249	23	by	by	IN
cord-263862-zzys31e9	249	24	NK	NK	NNP
cord-263862-zzys31e9	249	25	cells	cell	NNS
cord-263862-zzys31e9	249	26	,	,	,
cord-263862-zzys31e9	249	27	we	-PRON-	PRP
cord-263862-zzys31e9	249	28	immunised	immunise	VBD
cord-263862-zzys31e9	249	29	NK	NK	NNP
cord-263862-zzys31e9	249	30	cell	cell	NN
cord-263862-zzys31e9	249	31	depleted	deplete	VBD
cord-263862-zzys31e9	249	32	mice	mouse	NNS
cord-263862-zzys31e9	249	33	with	with	IN
cord-263862-zzys31e9	249	34	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	249	35	and	and	CC
cord-263862-zzys31e9	249	36	then	then	RB
cord-263862-zzys31e9	249	37	determined	determine	VBD
cord-263862-zzys31e9	249	38	the	the	DT
cord-263862-zzys31e9	249	39	levels	level	NNS
cord-263862-zzys31e9	249	40	of	of	IN
cord-263862-zzys31e9	249	41	circulating	circulate	VBG
cord-263862-zzys31e9	249	42	IFN-	IFN-	NNP
cord-263862-zzys31e9	249	43	␥	␥	ADD
cord-263862-zzys31e9	249	44	(	(	-LRB-
cord-263862-zzys31e9	249	45	Fig	Fig	NNP
cord-263862-zzys31e9	249	46	.	.	.
cord-263862-zzys31e9	249	47	4A	4a	CD
cord-263862-zzys31e9	249	48	)	)	-RRB-
cord-263862-zzys31e9	249	49	.	.	.
cord-263862-zzys31e9	250	1	The	the	DT
cord-263862-zzys31e9	250	2	IFN-	IFN-	NNP
cord-263862-zzys31e9	250	3	␥	␥	NNPS
cord-263862-zzys31e9	250	4	produced	produce	VBN
cord-263862-zzys31e9	250	5	in	in	IN
cord-263862-zzys31e9	250	6	response	response	NN
cord-263862-zzys31e9	250	7	to	to	IN
cord-263862-zzys31e9	250	8	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	250	9	in	in	IN
cord-263862-zzys31e9	250	10	the	the	DT
cord-263862-zzys31e9	250	11	NK	NK	NNP
cord-263862-zzys31e9	250	12	cell	cell	NN
cord-263862-zzys31e9	250	13	-	-	HYPH
cord-263862-zzys31e9	250	14	depleted	deplete	VBN
cord-263862-zzys31e9	250	15	mice	mouse	NNS
cord-263862-zzys31e9	250	16	was	be	VBD
cord-263862-zzys31e9	250	17	significantly	significantly	RB
cord-263862-zzys31e9	250	18	lower	low	JJR
cord-263862-zzys31e9	250	19	than	than	IN
cord-263862-zzys31e9	250	20	that	that	DT
cord-263862-zzys31e9	250	21	observed	observe	VBN
cord-263862-zzys31e9	250	22	in	in	IN
cord-263862-zzys31e9	250	23	mice	mouse	NNS
cord-263862-zzys31e9	250	24	treated	treat	VBN
cord-263862-zzys31e9	250	25	with	with	IN
cord-263862-zzys31e9	250	26	the	the	DT
cord-263862-zzys31e9	250	27	isotype	isotype	NN
cord-263862-zzys31e9	250	28	control	control	NN
cord-263862-zzys31e9	250	29	indicating	indicate	VBG
cord-263862-zzys31e9	250	30	that	that	IN
cord-263862-zzys31e9	250	31	NK	NK	NNP
cord-263862-zzys31e9	250	32	cells	cell	NNS
cord-263862-zzys31e9	250	33	are	be	VBP
cord-263862-zzys31e9	250	34	a	a	DT
cord-263862-zzys31e9	250	35	significant	significant	JJ
cord-263862-zzys31e9	250	36	source	source	NN
cord-263862-zzys31e9	250	37	of	of	IN
cord-263862-zzys31e9	250	38	the	the	DT
cord-263862-zzys31e9	250	39	IFN-	IFN-	NNP
cord-263862-zzys31e9	250	40	␥	␥	NNPS
cord-263862-zzys31e9	250	41	produced	produce	VBN
cord-263862-zzys31e9	250	42	.	.	.
cord-263862-zzys31e9	251	1	It	-PRON-	PRP
cord-263862-zzys31e9	251	2	has	have	VBZ
cord-263862-zzys31e9	251	3	been	be	VBN
cord-263862-zzys31e9	251	4	recently	recently	RB
cord-263862-zzys31e9	251	5	reported	report	VBN
cord-263862-zzys31e9	251	6	that	that	IN
cord-263862-zzys31e9	251	7	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	251	8	preferentially	preferentially	RB
cord-263862-zzys31e9	251	9	infects	infect	VBZ
cord-263862-zzys31e9	251	10	human	human	JJ
cord-263862-zzys31e9	251	11	cells	cell	NNS
cord-263862-zzys31e9	251	12	of	of	IN
cord-263862-zzys31e9	251	13	the	the	DT
cord-263862-zzys31e9	251	14	monocytic	monocytic	JJ
cord-263862-zzys31e9	251	15	lineage	lineage	NN
cord-263862-zzys31e9	251	16	and	and	CC
cord-263862-zzys31e9	251	17	was	be	VBD
cord-263862-zzys31e9	251	18	infact	infact	VBN
cord-263862-zzys31e9	251	19	unable	unable	JJ
cord-263862-zzys31e9	251	20	to	to	TO
cord-263862-zzys31e9	251	21	infect	infect	VB
cord-263862-zzys31e9	251	22	human	human	JJ
cord-263862-zzys31e9	251	23	NK	NK	NNP
cord-263862-zzys31e9	251	24	cells	cell	NNS
cord-263862-zzys31e9	251	25	in	in	IN
cord-263862-zzys31e9	251	26	vitro	vitro	FW
cord-263862-zzys31e9	251	27	[	[	-LRB-
cord-263862-zzys31e9	251	28	18	18	CD
cord-263862-zzys31e9	251	29	]	]	-RRB-
cord-263862-zzys31e9	251	30	.	.	.
cord-263862-zzys31e9	252	1	Our	-PRON-	PRP$
cord-263862-zzys31e9	252	2	data	data	NN
cord-263862-zzys31e9	252	3	indicates	indicate	VBZ
cord-263862-zzys31e9	252	4	that	that	IN
cord-263862-zzys31e9	252	5	in	in	IN
cord-263862-zzys31e9	252	6	a	a	DT
cord-263862-zzys31e9	252	7	mouse	mouse	NN
cord-263862-zzys31e9	252	8	model	model	NN
cord-263862-zzys31e9	252	9	,	,	,
cord-263862-zzys31e9	252	10	NK	NK	NNP
cord-263862-zzys31e9	252	11	cells	cell	NNS
cord-263862-zzys31e9	252	12	do	do	VBP
cord-263862-zzys31e9	252	13	play	play	VB
cord-263862-zzys31e9	252	14	a	a	DT
cord-263862-zzys31e9	252	15	crucial	crucial	JJ
cord-263862-zzys31e9	252	16	role	role	NN
cord-263862-zzys31e9	252	17	in	in	IN
cord-263862-zzys31e9	252	18	mediating	mediate	VBG
cord-263862-zzys31e9	252	19	the	the	DT
cord-263862-zzys31e9	252	20	inflammatory	inflammatory	JJ
cord-263862-zzys31e9	252	21	response	response	NN
cord-263862-zzys31e9	252	22	to	to	IN
cord-263862-zzys31e9	252	23	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	252	24	.	.	.
cord-263862-zzys31e9	253	1	Further	further	JJ
cord-263862-zzys31e9	253	2	studies	study	NNS
cord-263862-zzys31e9	253	3	with	with	IN
cord-263862-zzys31e9	253	4	human	human	JJ
cord-263862-zzys31e9	253	5	cells	cell	NNS
cord-263862-zzys31e9	253	6	in	in	IN
cord-263862-zzys31e9	253	7	vitro	vitro	FW
cord-263862-zzys31e9	253	8	or	or	CC
cord-263862-zzys31e9	253	9	ex	ex	FW
cord-263862-zzys31e9	253	10	vivo	vivo	NN
cord-263862-zzys31e9	253	11	are	be	VBP
cord-263862-zzys31e9	253	12	required	require	VBN
cord-263862-zzys31e9	253	13	to	to	TO
cord-263862-zzys31e9	253	14	determine	determine	VB
cord-263862-zzys31e9	253	15	the	the	DT
cord-263862-zzys31e9	253	16	role	role	NN
cord-263862-zzys31e9	253	17	of	of	IN
cord-263862-zzys31e9	253	18	NK	NK	NNP
cord-263862-zzys31e9	253	19	cells	cell	NNS
cord-263862-zzys31e9	253	20	in	in	IN
cord-263862-zzys31e9	253	21	the	the	DT
cord-263862-zzys31e9	253	22	innate	innate	JJ
cord-263862-zzys31e9	253	23	response	response	NN
cord-263862-zzys31e9	253	24	to	to	IN
cord-263862-zzys31e9	253	25	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	253	26	following	follow	VBG
cord-263862-zzys31e9	253	27	vaccination	vaccination	NN
cord-263862-zzys31e9	253	28	in	in	IN
cord-263862-zzys31e9	253	29	man	man	NN
cord-263862-zzys31e9	253	30	.	.	.
cord-263862-zzys31e9	254	1	Recently	recently	RB
cord-263862-zzys31e9	254	2	,	,	,
cord-263862-zzys31e9	254	3	it	-PRON-	PRP
cord-263862-zzys31e9	254	4	has	have	VBZ
cord-263862-zzys31e9	254	5	become	become	VBN
cord-263862-zzys31e9	254	6	clear	clear	JJ
cord-263862-zzys31e9	254	7	that	that	IN
cord-263862-zzys31e9	254	8	there	there	EX
cord-263862-zzys31e9	254	9	is	be	VBZ
cord-263862-zzys31e9	254	10	an	an	DT
cord-263862-zzys31e9	254	11	important	important	JJ
cord-263862-zzys31e9	254	12	bidirectional	bidirectional	JJ
cord-263862-zzys31e9	254	13	dialogue	dialogue	NN
cord-263862-zzys31e9	254	14	between	between	IN
cord-263862-zzys31e9	254	15	DC	DC	NNP
cord-263862-zzys31e9	254	16	and	and	CC
cord-263862-zzys31e9	254	17	NK	NK	NNP
cord-263862-zzys31e9	254	18	cells	cell	NNS
cord-263862-zzys31e9	254	19	(	(	-LRB-
cord-263862-zzys31e9	254	20	reviewed	review	VBN
cord-263862-zzys31e9	254	21	by	by	IN
cord-263862-zzys31e9	254	22	[	[	-LRB-
cord-263862-zzys31e9	254	23	10	10	CD
cord-263862-zzys31e9	254	24	]	]	-RRB-
cord-263862-zzys31e9	254	25	)	)	-RRB-
cord-263862-zzys31e9	254	26	.	.	.
cord-263862-zzys31e9	255	1	TLR	TLR	NNP
cord-263862-zzys31e9	255	2	-	-	HYPH
cord-263862-zzys31e9	255	3	dependent	dependent	JJ
cord-263862-zzys31e9	255	4	microbial	microbial	JJ
cord-263862-zzys31e9	255	5	stimuli	stimulus	NNS
cord-263862-zzys31e9	255	6	typically	typically	RB
cord-263862-zzys31e9	255	7	associated	associate	VBN
cord-263862-zzys31e9	255	8	with	with	IN
cord-263862-zzys31e9	255	9	Th1	th1	NN
cord-263862-zzys31e9	255	10	responses	response	NNS
cord-263862-zzys31e9	255	11	confer	confer	VBP
cord-263862-zzys31e9	255	12	on	on	IN
cord-263862-zzys31e9	255	13	DCs	dc	NNS
cord-263862-zzys31e9	255	14	the	the	DT
cord-263862-zzys31e9	255	15	ability	ability	NN
cord-263862-zzys31e9	255	16	to	to	TO
cord-263862-zzys31e9	255	17	activate	activate	VB
cord-263862-zzys31e9	255	18	NK	NK	NNP
cord-263862-zzys31e9	255	19	cells	cell	NNS
cord-263862-zzys31e9	255	20	[	[	-LRB-
cord-263862-zzys31e9	255	21	19	19	CD
cord-263862-zzys31e9	255	22	]	]	-RRB-
cord-263862-zzys31e9	255	23	to	to	TO
cord-263862-zzys31e9	255	24	secrete	secrete	VB
cord-263862-zzys31e9	255	25	IFN-	IFN-	NNP
cord-263862-zzys31e9	255	26	␥	␥	NFP
cord-263862-zzys31e9	255	27	directly	directly	RB
cord-263862-zzys31e9	255	28	or	or	CC
cord-263862-zzys31e9	255	29	induce	induce	VB
cord-263862-zzys31e9	255	30	NK	NK	NNP
cord-263862-zzys31e9	255	31	cells	cell	VBZ
cord-263862-zzys31e9	255	32	the	the	DT
cord-263862-zzys31e9	255	33	ability	ability	NN
cord-263862-zzys31e9	255	34	to	to	TO
cord-263862-zzys31e9	255	35	lyse	lyse	VB
cord-263862-zzys31e9	255	36	immature	immature	JJ
cord-263862-zzys31e9	255	37	DCs	dc	NNS
cord-263862-zzys31e9	255	38	[	[	-LRB-
cord-263862-zzys31e9	255	39	20	20	CD
cord-263862-zzys31e9	255	40	]	]	-RRB-
cord-263862-zzys31e9	255	41	.	.	.
cord-263862-zzys31e9	256	1	The	the	DT
cord-263862-zzys31e9	256	2	discovery	discovery	NN
cord-263862-zzys31e9	256	3	that	that	IN
cord-263862-zzys31e9	256	4	human	human	JJ
cord-263862-zzys31e9	256	5	NK	NK	NNP
cord-263862-zzys31e9	256	6	cells	cell	NNS
cord-263862-zzys31e9	256	7	express	express	VBP
cord-263862-zzys31e9	256	8	TLR3	TLR3	NNP
cord-263862-zzys31e9	256	9	and	and	CC
cord-263862-zzys31e9	256	10	TLR9	TLR9	NNP
cord-263862-zzys31e9	256	11	suggested	suggest	VBD
cord-263862-zzys31e9	256	12	the	the	DT
cord-263862-zzys31e9	256	13	existence	existence	NN
cord-263862-zzys31e9	256	14	of	of	IN
cord-263862-zzys31e9	256	15	TLR	TLR	NNP
cord-263862-zzys31e9	256	16	-	-	HYPH
cord-263862-zzys31e9	256	17	based	base	VBN
cord-263862-zzys31e9	256	18	NK	NK	NNP
cord-263862-zzys31e9	256	19	cell	cell	NN
cord-263862-zzys31e9	256	20	-	-	HYPH
cord-263862-zzys31e9	256	21	DC	dc	NN
cord-263862-zzys31e9	256	22	crosstalk	crosstalk	NN
cord-263862-zzys31e9	256	23	[	[	-LRB-
cord-263862-zzys31e9	256	24	21	21	CD
cord-263862-zzys31e9	256	25	]	]	-RRB-
cord-263862-zzys31e9	256	26	.	.	.
cord-263862-zzys31e9	257	1	This	this	DT
cord-263862-zzys31e9	257	2	might	may	MD
cord-263862-zzys31e9	257	3	be	be	VB
cord-263862-zzys31e9	257	4	relevant	relevant	JJ
cord-263862-zzys31e9	257	5	in	in	IN
cord-263862-zzys31e9	257	6	explaining	explain	VBG
cord-263862-zzys31e9	257	7	how	how	WRB
cord-263862-zzys31e9	257	8	NK	NK	NNP
cord-263862-zzys31e9	257	9	cells	cell	NNS
cord-263862-zzys31e9	257	10	and	and	CC
cord-263862-zzys31e9	257	11	DCs	dc	NNS
cord-263862-zzys31e9	257	12	can	can	MD
cord-263862-zzys31e9	257	13	be	be	VB
cord-263862-zzys31e9	257	14	activated	activate	VBN
cord-263862-zzys31e9	257	15	simultaneously	simultaneously	RB
cord-263862-zzys31e9	257	16	by	by	IN
cord-263862-zzys31e9	257	17	the	the	DT
cord-263862-zzys31e9	257	18	same	same	JJ
cord-263862-zzys31e9	257	19	pathogen	pathogen	NN
cord-263862-zzys31e9	257	20	and	and	CC
cord-263862-zzys31e9	257	21	build	build	VB
cord-263862-zzys31e9	257	22	an	an	DT
cord-263862-zzys31e9	257	23	efficient	efficient	JJ
cord-263862-zzys31e9	257	24	innate	innate	JJ
cord-263862-zzys31e9	257	25	immune	immune	JJ
cord-263862-zzys31e9	257	26	response	response	NN
cord-263862-zzys31e9	257	27	,	,	,
cord-263862-zzys31e9	257	28	which	which	WDT
cord-263862-zzys31e9	257	29	amplifies	amplify	VBZ
cord-263862-zzys31e9	257	30	the	the	DT
cord-263862-zzys31e9	257	31	downstream	downstream	JJ
cord-263862-zzys31e9	257	32	adaptive	adaptive	JJ
cord-263862-zzys31e9	257	33	Th1	th1	CD
cord-263862-zzys31e9	257	34	response	response	NN
cord-263862-zzys31e9	257	35	[	[	-LRB-
cord-263862-zzys31e9	257	36	10	10	CD
cord-263862-zzys31e9	257	37	]	]	-RRB-
cord-263862-zzys31e9	257	38	.	.	.
cord-263862-zzys31e9	258	1	A	a	DT
cord-263862-zzys31e9	258	2	previous	previous	JJ
cord-263862-zzys31e9	258	3	report	report	NN
cord-263862-zzys31e9	258	4	showed	show	VBD
cord-263862-zzys31e9	258	5	that	that	IN
cord-263862-zzys31e9	258	6	both	both	CC
cord-263862-zzys31e9	258	7	mature	mature	JJ
cord-263862-zzys31e9	258	8	and	and	CC
cord-263862-zzys31e9	258	9	immature	immature	JJ
cord-263862-zzys31e9	258	10	human	human	JJ
cord-263862-zzys31e9	258	11	DCs	dc	NNS
cord-263862-zzys31e9	258	12	could	could	MD
cord-263862-zzys31e9	258	13	be	be	VB
cord-263862-zzys31e9	258	14	successfully	successfully	RB
cord-263862-zzys31e9	258	15	infected	infect	VBN
cord-263862-zzys31e9	258	16	with	with	IN
cord-263862-zzys31e9	258	17	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	258	18	[	[	-LRB-
cord-263862-zzys31e9	258	19	9	9	CD
cord-263862-zzys31e9	258	20	]	]	-RRB-
cord-263862-zzys31e9	258	21	.	.	.
cord-263862-zzys31e9	259	1	Many	many	JJ
cord-263862-zzys31e9	259	2	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	259	3	infected	infect	VBD
cord-263862-zzys31e9	259	4	immature	immature	JJ
cord-263862-zzys31e9	259	5	DCs	dc	NNS
cord-263862-zzys31e9	259	6	rapidly	rapidly	RB
cord-263862-zzys31e9	259	7	underwent	undergo	VBD
cord-263862-zzys31e9	259	8	apoptosis	apoptosis	NN
cord-263862-zzys31e9	259	9	,	,	,
cord-263862-zzys31e9	259	10	and	and	CC
cord-263862-zzys31e9	259	11	the	the	DT
cord-263862-zzys31e9	259	12	endocytosis	endocytosis	NN
cord-263862-zzys31e9	259	13	of	of	IN
cord-263862-zzys31e9	259	14	infected	infect	VBN
cord-263862-zzys31e9	259	15	,	,	,
cord-263862-zzys31e9	259	16	dead	dead	JJ
cord-263862-zzys31e9	259	17	or	or	CC
cord-263862-zzys31e9	259	18	dying	die	VBG
cord-263862-zzys31e9	259	19	DCs	dc	NNS
cord-263862-zzys31e9	259	20	by	by	IN
cord-263862-zzys31e9	259	21	uninfected	uninfected	JJ
cord-263862-zzys31e9	259	22	immature	immature	JJ
cord-263862-zzys31e9	259	23	DCs	dc	NNS
cord-263862-zzys31e9	259	24	was	be	VBD
cord-263862-zzys31e9	259	25	observed	observe	VBN
cord-263862-zzys31e9	259	26	.	.	.
cord-263862-zzys31e9	260	1	Concurrently	concurrently	RB
cord-263862-zzys31e9	260	2	,	,	,
cord-263862-zzys31e9	260	3	a	a	DT
cord-263862-zzys31e9	260	4	sub	sub	NN
cord-263862-zzys31e9	260	5	-	-	JJ
cord-263862-zzys31e9	260	6	population	population	NN
cord-263862-zzys31e9	260	7	of	of	IN
cord-263862-zzys31e9	260	8	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	260	9	-	-	HYPH
cord-263862-zzys31e9	260	10	exposed	expose	VBN
cord-263862-zzys31e9	260	11	DCs	DCs	NNP
cord-263862-zzys31e9	260	12	matured	mature	VBN
cord-263862-zzys31e9	260	13	.	.	.
cord-263862-zzys31e9	261	1	Maturation	maturation	NN
cord-263862-zzys31e9	261	2	was	be	VBD
cord-263862-zzys31e9	261	3	driven	drive	VBN
cord-263862-zzys31e9	261	4	by	by	IN
cord-263862-zzys31e9	261	5	the	the	DT
cord-263862-zzys31e9	261	6	TNF-	TNF-	NNP
cord-263862-zzys31e9	261	7	␣	␣	NN
cord-263862-zzys31e9	261	8	secreted	secrete	VBD
cord-263862-zzys31e9	261	9	following	follow	VBG
cord-263862-zzys31e9	261	10	exposure	exposure	NN
cord-263862-zzys31e9	261	11	to	to	IN
cord-263862-zzys31e9	261	12	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	261	13	and	and	CC
cord-263862-zzys31e9	261	14	partially	partially	RB
cord-263862-zzys31e9	261	15	by	by	IN
cord-263862-zzys31e9	261	16	the	the	DT
cord-263862-zzys31e9	261	17	ingestion	ingestion	NN
cord-263862-zzys31e9	261	18	of	of	IN
cord-263862-zzys31e9	261	19	infected	infected	JJ
cord-263862-zzys31e9	261	20	cell	cell	NN
cord-263862-zzys31e9	261	21	debris	debris	NN
cord-263862-zzys31e9	261	22	[	[	-LRB-
cord-263862-zzys31e9	261	23	9	9	CD
cord-263862-zzys31e9	261	24	]	]	-RRB-
cord-263862-zzys31e9	261	25	.	.	.
cord-263862-zzys31e9	262	1	We	-PRON-	PRP
cord-263862-zzys31e9	262	2	investigated	investigate	VBD
cord-263862-zzys31e9	262	3	the	the	DT
cord-263862-zzys31e9	262	4	effect	effect	NN
cord-263862-zzys31e9	262	5	of	of	IN
cord-263862-zzys31e9	262	6	exposing	expose	VBG
cord-263862-zzys31e9	262	7	murine	murine	JJ
cord-263862-zzys31e9	262	8	BMDCs	bmdc	NNS
cord-263862-zzys31e9	262	9	to	to	IN
cord-263862-zzys31e9	262	10	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	262	11	in	in	IN
cord-263862-zzys31e9	262	12	vitro	vitro	FW
cord-263862-zzys31e9	262	13	and	and	CC
cord-263862-zzys31e9	262	14	found	find	VBD
cord-263862-zzys31e9	262	15	that	that	IN
cord-263862-zzys31e9	262	16	exposure	exposure	NN
cord-263862-zzys31e9	262	17	for	for	IN
cord-263862-zzys31e9	262	18	24	24	CD
cord-263862-zzys31e9	262	19	h	h	NN
cord-263862-zzys31e9	262	20	to	to	IN
cord-263862-zzys31e9	262	21	a	a	DT
cord-263862-zzys31e9	262	22	MOI	moi	NN
cord-263862-zzys31e9	262	23	of	of	IN
cord-263862-zzys31e9	262	24	0.2	0.2	CD
cord-263862-zzys31e9	262	25	(	(	-LRB-
cord-263862-zzys31e9	262	26	conditions	condition	NNS
cord-263862-zzys31e9	262	27	that	that	WDT
cord-263862-zzys31e9	262	28	did	do	VBD
cord-263862-zzys31e9	262	29	not	not	RB
cord-263862-zzys31e9	262	30	induce	induce	VB
cord-263862-zzys31e9	262	31	a	a	DT
cord-263862-zzys31e9	262	32	significant	significant	JJ
cord-263862-zzys31e9	262	33	amount	amount	NN
cord-263862-zzys31e9	262	34	of	of	IN
cord-263862-zzys31e9	262	35	apoptosis	apoptosis	NN
cord-263862-zzys31e9	262	36	)	)	-RRB-
cord-263862-zzys31e9	262	37	did	do	VBD
cord-263862-zzys31e9	262	38	activate	activate	VB
cord-263862-zzys31e9	262	39	DCs	dc	NNS
cord-263862-zzys31e9	262	40	as	as	IN
cord-263862-zzys31e9	262	41	evidenced	evidence	VBN
cord-263862-zzys31e9	262	42	by	by	IN
cord-263862-zzys31e9	262	43	their	-PRON-	PRP$
cord-263862-zzys31e9	262	44	up	up	JJ
cord-263862-zzys31e9	262	45	-	-	HYPH
cord-263862-zzys31e9	262	46	regulation	regulation	NN
cord-263862-zzys31e9	262	47	of	of	IN
cord-263862-zzys31e9	262	48	the	the	DT
cord-263862-zzys31e9	262	49	co	co	JJ
cord-263862-zzys31e9	262	50	-	-	JJ
cord-263862-zzys31e9	262	51	stimulatory	stimulatory	JJ
cord-263862-zzys31e9	262	52	molecules	molecule	NNS
cord-263862-zzys31e9	262	53	CD40	CD40	NNP
cord-263862-zzys31e9	262	54	,	,	,
cord-263862-zzys31e9	262	55	CD80	CD80	NNP
cord-263862-zzys31e9	262	56	and	and	CC
cord-263862-zzys31e9	262	57	CD86	CD86	NNP
cord-263862-zzys31e9	262	58	(	(	-LRB-
cord-263862-zzys31e9	262	59	Fig	Fig	NNP
cord-263862-zzys31e9	262	60	.	.	.
cord-263862-zzys31e9	262	61	5	5	CD
cord-263862-zzys31e9	262	62	)	)	-RRB-
cord-263862-zzys31e9	262	63	.	.	.
cord-263862-zzys31e9	263	1	Additionally	additionally	RB
cord-263862-zzys31e9	263	2	,	,	,
cord-263862-zzys31e9	263	3	exposure	exposure	NN
cord-263862-zzys31e9	263	4	to	to	IN
cord-263862-zzys31e9	263	5	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	263	6	induced	induce	VBN
cord-263862-zzys31e9	263	7	murine	murine	JJ
cord-263862-zzys31e9	263	8	BMDCs	bmdc	NNS
cord-263862-zzys31e9	263	9	to	to	TO
cord-263862-zzys31e9	263	10	secrete	secrete	VB
cord-263862-zzys31e9	263	11	significant	significant	JJ
cord-263862-zzys31e9	263	12	quantities	quantity	NNS
cord-263862-zzys31e9	263	13	of	of	IN
cord-263862-zzys31e9	263	14	the	the	DT
cord-263862-zzys31e9	263	15	chemokines	chemokine	NNS
cord-263862-zzys31e9	263	16	CXCL10	CXCL10	NNP
cord-263862-zzys31e9	263	17	and	and	CC
cord-263862-zzys31e9	263	18	CCL2	CCL2	NNP
cord-263862-zzys31e9	264	1	(	(	-LRB-
cord-263862-zzys31e9	264	2	Fig	Fig	NNP
cord-263862-zzys31e9	264	3	.	.	.
cord-263862-zzys31e9	264	4	6	6	CD
cord-263862-zzys31e9	264	5	)	)	-RRB-
cord-263862-zzys31e9	264	6	.	.	.
cord-263862-zzys31e9	265	1	CXCL10	CXCL10	NNP
cord-263862-zzys31e9	265	2	(	(	-LRB-
cord-263862-zzys31e9	265	3	IP-10	IP-10	NNP
cord-263862-zzys31e9	265	4	)	)	-RRB-
cord-263862-zzys31e9	265	5	is	be	VBZ
cord-263862-zzys31e9	265	6	chemotactic	chemotactic	VBN
cord-263862-zzys31e9	265	7	for	for	IN
cord-263862-zzys31e9	265	8	T	T	NNP
cord-263862-zzys31e9	265	9	cells	cell	NNS
cord-263862-zzys31e9	265	10	[	[	-LRB-
cord-263862-zzys31e9	265	11	22	22	CD
cord-263862-zzys31e9	265	12	]	]	-RRB-
cord-263862-zzys31e9	265	13	and	and	CC
cord-263862-zzys31e9	265	14	NK	NK	NNP
cord-263862-zzys31e9	265	15	cells	cell	NNS
cord-263862-zzys31e9	265	16	[	[	-LRB-
cord-263862-zzys31e9	265	17	23	23	CD
cord-263862-zzys31e9	265	18	]	]	-RRB-
cord-263862-zzys31e9	265	19	expressing	express	VBG
cord-263862-zzys31e9	265	20	CXCR3	cxcr3	XX
cord-263862-zzys31e9	265	21	.	.	.
cord-263862-zzys31e9	266	1	While	while	IN
cord-263862-zzys31e9	266	2	CCL2	CCL2	NNP
cord-263862-zzys31e9	266	3	(	(	-LRB-
cord-263862-zzys31e9	266	4	MCP-1	MCP-1	NNP
cord-263862-zzys31e9	266	5	)	)	-RRB-
cord-263862-zzys31e9	266	6	plays	play	VBZ
cord-263862-zzys31e9	266	7	a	a	DT
cord-263862-zzys31e9	266	8	role	role	NN
cord-263862-zzys31e9	266	9	in	in	IN
cord-263862-zzys31e9	266	10	the	the	DT
cord-263862-zzys31e9	266	11	recruitment	recruitment	NN
cord-263862-zzys31e9	266	12	of	of	IN
cord-263862-zzys31e9	266	13	monocytes	monocyte	NNS
cord-263862-zzys31e9	266	14	/	/	SYM
cord-263862-zzys31e9	266	15	macrophages	macrophage	NNS
cord-263862-zzys31e9	266	16	by	by	IN
cord-263862-zzys31e9	266	17	interacting	interact	VBG
cord-263862-zzys31e9	266	18	with	with	IN
cord-263862-zzys31e9	266	19	CCR2	CCR2	NNP
cord-263862-zzys31e9	266	20	.	.	.
cord-263862-zzys31e9	267	1	Recent	recent	JJ
cord-263862-zzys31e9	267	2	studies	study	NNS
cord-263862-zzys31e9	267	3	with	with	IN
cord-263862-zzys31e9	267	4	CXCL10	cxcl10	CD
cord-263862-zzys31e9	267	5	neutralising	neutralise	VBG
cord-263862-zzys31e9	267	6	antibodies	antibody	NNS
cord-263862-zzys31e9	267	7	or	or	CC
cord-263862-zzys31e9	267	8	CXCL10	cxcl10	NN
cord-263862-zzys31e9	267	9	−/−	−/−	NNP
cord-263862-zzys31e9	267	10	mice	mouse	NNS
cord-263862-zzys31e9	267	11	demonstrate	demonstrate	VBP
cord-263862-zzys31e9	267	12	that	that	IN
cord-263862-zzys31e9	267	13	the	the	DT
cord-263862-zzys31e9	267	14	absence	absence	NN
cord-263862-zzys31e9	267	15	of	of	IN
cord-263862-zzys31e9	267	16	functional	functional	JJ
cord-263862-zzys31e9	267	17	CXCL10	CXCL10	NNP
cord-263862-zzys31e9	267	18	results	result	NNS
cord-263862-zzys31e9	267	19	in	in	IN
cord-263862-zzys31e9	267	20	increased	increase	VBN
cord-263862-zzys31e9	267	21	mortality	mortality	NN
cord-263862-zzys31e9	267	22	and	and	CC
cord-263862-zzys31e9	267	23	reduced	reduce	VBN
cord-263862-zzys31e9	267	24	T	t	NN
cord-263862-zzys31e9	267	25	cell	cell	NN
cord-263862-zzys31e9	267	26	infiltration	infiltration	NN
cord-263862-zzys31e9	267	27	within	within	IN
cord-263862-zzys31e9	267	28	the	the	DT
cord-263862-zzys31e9	267	29	brains	brain	NNS
cord-263862-zzys31e9	267	30	of	of	IN
cord-263862-zzys31e9	267	31	mice	mouse	NNS
cord-263862-zzys31e9	267	32	infected	infect	VBN
cord-263862-zzys31e9	267	33	intracerebrally	intracerebrally	RB
cord-263862-zzys31e9	267	34	with	with	IN
cord-263862-zzys31e9	267	35	a	a	DT
cord-263862-zzys31e9	267	36	murine	murine	JJ
cord-263862-zzys31e9	267	37	coronavirus	coronavirus	NN
cord-263862-zzys31e9	267	38	[	[	-LRB-
cord-263862-zzys31e9	267	39	22	22	CD
cord-263862-zzys31e9	267	40	,	,	,
cord-263862-zzys31e9	267	41	24	24	CD
cord-263862-zzys31e9	267	42	]	]	-RRB-
cord-263862-zzys31e9	267	43	,	,	,
cord-263862-zzys31e9	267	44	illustrating	illustrate	VBG
cord-263862-zzys31e9	267	45	the	the	DT
cord-263862-zzys31e9	267	46	importance	importance	NN
cord-263862-zzys31e9	267	47	of	of	IN
cord-263862-zzys31e9	267	48	this	this	DT
cord-263862-zzys31e9	267	49	chemokine	chemokine	NN
cord-263862-zzys31e9	267	50	in	in	IN
cord-263862-zzys31e9	267	51	co	co	JJ
cord-263862-zzys31e9	267	52	-	-	JJ
cord-263862-zzys31e9	267	53	ordinating	ordinate	VBG
cord-263862-zzys31e9	267	54	a	a	DT
cord-263862-zzys31e9	267	55	protective	protective	JJ
cord-263862-zzys31e9	267	56	immune	immune	JJ
cord-263862-zzys31e9	267	57	response	response	NN
cord-263862-zzys31e9	267	58	against	against	IN
cord-263862-zzys31e9	267	59	a	a	DT
cord-263862-zzys31e9	267	60	viral	viral	JJ
cord-263862-zzys31e9	267	61	pathogen	pathogen	NN
cord-263862-zzys31e9	267	62	.	.	.
cord-263862-zzys31e9	268	1	CCL2	CCL2	NNP
cord-263862-zzys31e9	268	2	's	's	POS
cord-263862-zzys31e9	268	3	interaction	interaction	NN
cord-263862-zzys31e9	268	4	with	with	IN
cord-263862-zzys31e9	268	5	CCR2	CCR2	NNP
cord-263862-zzys31e9	268	6	is	be	VBZ
cord-263862-zzys31e9	268	7	an	an	DT
cord-263862-zzys31e9	268	8	important	important	JJ
cord-263862-zzys31e9	268	9	factor	factor	NN
cord-263862-zzys31e9	268	10	promoting	promote	VBG
cord-263862-zzys31e9	268	11	early	early	JJ
cord-263862-zzys31e9	268	12	inflammatory	inflammatory	JJ
cord-263862-zzys31e9	268	13	responses	response	NNS
cord-263862-zzys31e9	268	14	and	and	CC
cord-263862-zzys31e9	268	15	effective	effective	JJ
cord-263862-zzys31e9	268	16	local	local	JJ
cord-263862-zzys31e9	268	17	antiviral	antiviral	JJ
cord-263862-zzys31e9	268	18	defense	defense	NN
cord-263862-zzys31e9	268	19	[	[	-LRB-
cord-263862-zzys31e9	268	20	25	25	CD
cord-263862-zzys31e9	268	21	]	]	-RRB-
cord-263862-zzys31e9	268	22	.	.	.
cord-263862-zzys31e9	269	1	The	the	DT
cord-263862-zzys31e9	269	2	ability	ability	NN
cord-263862-zzys31e9	269	3	of	of	IN
cord-263862-zzys31e9	269	4	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	269	5	to	to	TO
cord-263862-zzys31e9	269	6	induce	induce	VB
cord-263862-zzys31e9	269	7	DCs	dc	NNS
cord-263862-zzys31e9	269	8	to	to	IN
cord-263862-zzys31e9	269	9	secrete	secrete	VB
cord-263862-zzys31e9	269	10	chemokines	chemokine	NNS
cord-263862-zzys31e9	269	11	,	,	,
cord-263862-zzys31e9	269	12	such	such	JJ
cord-263862-zzys31e9	269	13	as	as	IN
cord-263862-zzys31e9	269	14	CXCL10	CXCL10	NNP
cord-263862-zzys31e9	269	15	may	may	MD
cord-263862-zzys31e9	269	16	provide	provide	VB
cord-263862-zzys31e9	269	17	the	the	DT
cord-263862-zzys31e9	269	18	signal	signal	NN
cord-263862-zzys31e9	269	19	required	require	VBN
cord-263862-zzys31e9	269	20	for	for	IN
cord-263862-zzys31e9	269	21	NK	NK	NNP
cord-263862-zzys31e9	269	22	cells	cell	NNS
cord-263862-zzys31e9	269	23	to	to	TO
cord-263862-zzys31e9	269	24	migrate	migrate	VB
cord-263862-zzys31e9	269	25	to	to	IN
cord-263862-zzys31e9	269	26	DC	DC	NNP
cord-263862-zzys31e9	269	27	-	-	HYPH
cord-263862-zzys31e9	269	28	rich	rich	JJ
cord-263862-zzys31e9	269	29	areas	area	NNS
cord-263862-zzys31e9	269	30	bringing	bring	VBG
cord-263862-zzys31e9	269	31	them	-PRON-	PRP
cord-263862-zzys31e9	269	32	in	in	IN
cord-263862-zzys31e9	269	33	close	close	JJ
cord-263862-zzys31e9	269	34	proximity	proximity	NN
cord-263862-zzys31e9	269	35	enabling	enable	VBG
cord-263862-zzys31e9	269	36	direct	direct	JJ
cord-263862-zzys31e9	269	37	cell	cell	NN
cord-263862-zzys31e9	269	38	-	-	HYPH
cord-263862-zzys31e9	269	39	cell	cell	NN
cord-263862-zzys31e9	269	40	contact	contact	NN
cord-263862-zzys31e9	269	41	,	,	,
cord-263862-zzys31e9	269	42	thereby	thereby	RB
cord-263862-zzys31e9	269	43	resulting	result	VBG
cord-263862-zzys31e9	269	44	in	in	IN
cord-263862-zzys31e9	269	45	downstream	downstream	JJ
cord-263862-zzys31e9	269	46	Th1	th1	NN
cord-263862-zzys31e9	269	47	responses	response	NNS
cord-263862-zzys31e9	269	48	.	.	.
cord-263862-zzys31e9	270	1	We	-PRON-	PRP
cord-263862-zzys31e9	270	2	found	find	VBD
cord-263862-zzys31e9	270	3	that	that	IN
cord-263862-zzys31e9	270	4	there	there	EX
cord-263862-zzys31e9	270	5	was	be	VBD
cord-263862-zzys31e9	270	6	a	a	DT
cord-263862-zzys31e9	270	7	significant	significant	JJ
cord-263862-zzys31e9	270	8	increase	increase	NN
cord-263862-zzys31e9	270	9	in	in	IN
cord-263862-zzys31e9	270	10	both	both	DT
cord-263862-zzys31e9	270	11	size	size	NN
cord-263862-zzys31e9	270	12	and	and	CC
cord-263862-zzys31e9	270	13	cellularity	cellularity	NN
cord-263862-zzys31e9	270	14	in	in	IN
cord-263862-zzys31e9	270	15	the	the	DT
cord-263862-zzys31e9	270	16	local	local	JJ
cord-263862-zzys31e9	270	17	draining	drain	VBG
cord-263862-zzys31e9	270	18	lymph	lymph	NN
cord-263862-zzys31e9	270	19	node	node	NN
cord-263862-zzys31e9	270	20	following	follow	VBG
cord-263862-zzys31e9	270	21	injection	injection	NN
cord-263862-zzys31e9	270	22	with	with	IN
cord-263862-zzys31e9	270	23	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	270	24	(	(	-LRB-
cord-263862-zzys31e9	270	25	data	datum	NNS
cord-263862-zzys31e9	270	26	not	not	RB
cord-263862-zzys31e9	270	27	shown	show	VBN
cord-263862-zzys31e9	270	28	)	)	-RRB-
cord-263862-zzys31e9	270	29	.	.	.
cord-263862-zzys31e9	271	1	Using	use	VBG
cord-263862-zzys31e9	271	2	flow	flow	NN
cord-263862-zzys31e9	271	3	cytometric	cytometric	NN
cord-263862-zzys31e9	271	4	analysis	analysis	NN
cord-263862-zzys31e9	271	5	of	of	IN
cord-263862-zzys31e9	271	6	the	the	DT
cord-263862-zzys31e9	271	7	lymph	lymph	NN
cord-263862-zzys31e9	271	8	node	node	NN
cord-263862-zzys31e9	271	9	cells	cell	NNS
cord-263862-zzys31e9	271	10	we	-PRON-	PRP
cord-263862-zzys31e9	271	11	could	could	MD
cord-263862-zzys31e9	271	12	not	not	RB
cord-263862-zzys31e9	271	13	determine	determine	VB
cord-263862-zzys31e9	271	14	a	a	DT
cord-263862-zzys31e9	271	15	change	change	NN
cord-263862-zzys31e9	271	16	in	in	IN
cord-263862-zzys31e9	271	17	the	the	DT
cord-263862-zzys31e9	271	18	%	%	NN
cord-263862-zzys31e9	271	19	of	of	IN
cord-263862-zzys31e9	271	20	any	any	DT
cord-263862-zzys31e9	271	21	cell	cell	NN
cord-263862-zzys31e9	271	22	type	type	NN
cord-263862-zzys31e9	271	23	(	(	-LRB-
cord-263862-zzys31e9	271	24	data	datum	NNS
cord-263862-zzys31e9	271	25	not	not	RB
cord-263862-zzys31e9	271	26	shown	show	VBN
cord-263862-zzys31e9	271	27	)	)	-RRB-
cord-263862-zzys31e9	271	28	.	.	.
cord-263862-zzys31e9	272	1	These	these	DT
cord-263862-zzys31e9	272	2	data	datum	NNS
cord-263862-zzys31e9	272	3	in	in	IN
cord-263862-zzys31e9	272	4	conjunction	conjunction	NN
cord-263862-zzys31e9	272	5	with	with	IN
cord-263862-zzys31e9	272	6	previous	previous	JJ
cord-263862-zzys31e9	272	7	work	work	NN
cord-263862-zzys31e9	272	8	by	by	IN
cord-263862-zzys31e9	272	9	Boudet	Boudet	NNP
cord-263862-zzys31e9	272	10	et	et	NNP
cord-263862-zzys31e9	272	11	al	al	NNP
cord-263862-zzys31e9	272	12	.	.	.
cord-263862-zzys31e9	273	1	demonstrate	demonstrate	VB
cord-263862-zzys31e9	273	2	that	that	IN
cord-263862-zzys31e9	273	3	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	273	4	can	can	MD
cord-263862-zzys31e9	273	5	trigger	trigger	VB
cord-263862-zzys31e9	273	6	an	an	DT
cord-263862-zzys31e9	273	7	inflammatory	inflammatory	JJ
cord-263862-zzys31e9	273	8	response	response	NN
cord-263862-zzys31e9	273	9	,	,	,
cord-263862-zzys31e9	273	10	induce	induce	VB
cord-263862-zzys31e9	273	11	the	the	DT
cord-263862-zzys31e9	273	12	migration	migration	NN
cord-263862-zzys31e9	273	13	of	of	IN
cord-263862-zzys31e9	273	14	neutrophils	neutrophil	NNS
cord-263862-zzys31e9	273	15	to	to	IN
cord-263862-zzys31e9	273	16	the	the	DT
cord-263862-zzys31e9	273	17	site	site	NN
cord-263862-zzys31e9	273	18	of	of	IN
cord-263862-zzys31e9	273	19	inoculation	inoculation	NN
cord-263862-zzys31e9	273	20	within	within	IN
cord-263862-zzys31e9	273	21	6	6	CD
cord-263862-zzys31e9	273	22	h	h	NN
cord-263862-zzys31e9	273	23	of	of	IN
cord-263862-zzys31e9	273	24	administration	administration	NN
cord-263862-zzys31e9	273	25	[	[	-LRB-
cord-263862-zzys31e9	273	26	7	7	CD
cord-263862-zzys31e9	273	27	]	]	-RRB-
cord-263862-zzys31e9	273	28	and	and	CC
cord-263862-zzys31e9	273	29	enlargement	enlargement	NN
cord-263862-zzys31e9	273	30	of	of	IN
cord-263862-zzys31e9	273	31	the	the	DT
cord-263862-zzys31e9	273	32	local	local	JJ
cord-263862-zzys31e9	273	33	draining	drain	VBG
cord-263862-zzys31e9	273	34	lymph	lymph	NN
cord-263862-zzys31e9	273	35	node	node	NN
cord-263862-zzys31e9	273	36	.	.	.
cord-263862-zzys31e9	274	1	Therefore	therefore	RB
cord-263862-zzys31e9	274	2	,	,	,
cord-263862-zzys31e9	274	3	we	-PRON-	PRP
cord-263862-zzys31e9	274	4	now	now	RB
cord-263862-zzys31e9	274	5	propose	propose	VBP
cord-263862-zzys31e9	274	6	the	the	DT
cord-263862-zzys31e9	274	7	following	following	JJ
cord-263862-zzys31e9	274	8	mechanism	mechanism	NN
cord-263862-zzys31e9	274	9	for	for	IN
cord-263862-zzys31e9	274	10	the	the	DT
cord-263862-zzys31e9	274	11	adjuvanticity	adjuvanticity	NN
cord-263862-zzys31e9	274	12	of	of	IN
cord-263862-zzys31e9	274	13	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	274	14	:	:	:
cord-263862-zzys31e9	274	15	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	274	16	causes	cause	VBZ
cord-263862-zzys31e9	274	17	inflammation	inflammation	NN
cord-263862-zzys31e9	274	18	,	,	,
cord-263862-zzys31e9	274	19	and	and	CC
cord-263862-zzys31e9	274	20	PMN	PMN	NNP
cord-263862-zzys31e9	274	21	recruitment	recruitment	NN
cord-263862-zzys31e9	274	22	to	to	IN
cord-263862-zzys31e9	274	23	the	the	DT
cord-263862-zzys31e9	274	24	site	site	NN
cord-263862-zzys31e9	274	25	of	of	IN
cord-263862-zzys31e9	274	26	injection	injection	NN
cord-263862-zzys31e9	274	27	[	[	-LRB-
cord-263862-zzys31e9	274	28	7	7	CD
cord-263862-zzys31e9	274	29	]	]	-RRB-
cord-263862-zzys31e9	274	30	.	.	.
cord-263862-zzys31e9	275	1	This	this	DT
cord-263862-zzys31e9	275	2	,	,	,
cord-263862-zzys31e9	275	3	in	in	IN
cord-263862-zzys31e9	275	4	turn	turn	NN
cord-263862-zzys31e9	275	5	,	,	,
cord-263862-zzys31e9	275	6	causes	cause	VBZ
cord-263862-zzys31e9	275	7	the	the	DT
cord-263862-zzys31e9	275	8	activation	activation	NN
cord-263862-zzys31e9	275	9	of	of	IN
cord-263862-zzys31e9	275	10	local	local	JJ
cord-263862-zzys31e9	275	11	DCs	dc	NNS
cord-263862-zzys31e9	275	12	(	(	-LRB-
cord-263862-zzys31e9	275	13	as	as	IN
cord-263862-zzys31e9	275	14	demonstrated	demonstrate	VBN
cord-263862-zzys31e9	275	15	by	by	IN
cord-263862-zzys31e9	275	16	increased	increase	VBN
cord-263862-zzys31e9	275	17	co	co	JJ
cord-263862-zzys31e9	275	18	-	-	JJ
cord-263862-zzys31e9	275	19	stimulatory	stimulatory	JJ
cord-263862-zzys31e9	275	20	molecule	molecule	NN
cord-263862-zzys31e9	275	21	expression	expression	NN
cord-263862-zzys31e9	275	22	)	)	-RRB-
cord-263862-zzys31e9	275	23	.	.	.
cord-263862-zzys31e9	276	1	These	these	DT
cord-263862-zzys31e9	276	2	cells	cell	NNS
cord-263862-zzys31e9	276	3	may	may	MD
cord-263862-zzys31e9	276	4	then	then	RB
cord-263862-zzys31e9	276	5	migrate	migrate	VB
cord-263862-zzys31e9	276	6	to	to	IN
cord-263862-zzys31e9	276	7	the	the	DT
cord-263862-zzys31e9	276	8	local	local	JJ
cord-263862-zzys31e9	276	9	draining	drain	VBG
cord-263862-zzys31e9	276	10	lymph	lymph	NN
cord-263862-zzys31e9	276	11	node	node	NN
cord-263862-zzys31e9	276	12	.	.	.
cord-263862-zzys31e9	277	1	Here	here	RB
cord-263862-zzys31e9	277	2	,	,	,
cord-263862-zzys31e9	277	3	DC	DC	NNP
cord-263862-zzys31e9	277	4	secretion	secretion	NN
cord-263862-zzys31e9	277	5	of	of	IN
cord-263862-zzys31e9	277	6	chemokines	chemokine	NNS
cord-263862-zzys31e9	277	7	including	include	VBG
cord-263862-zzys31e9	277	8	CCL2	CCL2	NNP
cord-263862-zzys31e9	277	9	and	and	CC
cord-263862-zzys31e9	277	10	CXCL10	CXCL10	NNP
cord-263862-zzys31e9	277	11	cause	cause	VB
cord-263862-zzys31e9	277	12	an	an	DT
cord-263862-zzys31e9	277	13	influx	influx	NN
cord-263862-zzys31e9	277	14	of	of	IN
cord-263862-zzys31e9	277	15	cells	cell	NNS
cord-263862-zzys31e9	277	16	including	include	VBG
cord-263862-zzys31e9	277	17	NK	NK	NNP
cord-263862-zzys31e9	277	18	and	and	CC
cord-263862-zzys31e9	277	19	T	T	NNP
cord-263862-zzys31e9	277	20	cells	cell	NNS
cord-263862-zzys31e9	277	21	.	.	.
cord-263862-zzys31e9	278	1	The	the	DT
cord-263862-zzys31e9	278	2	interaction	interaction	NN
cord-263862-zzys31e9	278	3	of	of	IN
cord-263862-zzys31e9	278	4	the	the	DT
cord-263862-zzys31e9	278	5	DC	DC	NNP
cord-263862-zzys31e9	278	6	and	and	CC
cord-263862-zzys31e9	278	7	NK	NK	NNP
cord-263862-zzys31e9	278	8	cells	cell	NNS
cord-263862-zzys31e9	278	9	in	in	IN
cord-263862-zzys31e9	278	10	the	the	DT
cord-263862-zzys31e9	278	11	local	local	JJ
cord-263862-zzys31e9	278	12	lymph	lymph	NN
cord-263862-zzys31e9	278	13	node	node	NN
cord-263862-zzys31e9	278	14	triggers	trigger	VBZ
cord-263862-zzys31e9	278	15	IFN-	IFN-	NNP
cord-263862-zzys31e9	278	16	␥	␥	CD
cord-263862-zzys31e9	278	17	secretion	secretion	NN
cord-263862-zzys31e9	278	18	by	by	IN
cord-263862-zzys31e9	278	19	the	the	DT
cord-263862-zzys31e9	278	20	NK	NK	NNP
cord-263862-zzys31e9	278	21	cells	cell	NNS
cord-263862-zzys31e9	278	22	that	that	WDT
cord-263862-zzys31e9	278	23	results	result	VBZ
cord-263862-zzys31e9	278	24	in	in	IN
cord-263862-zzys31e9	278	25	an	an	DT
cord-263862-zzys31e9	278	26	increase	increase	NN
cord-263862-zzys31e9	278	27	in	in	IN
cord-263862-zzys31e9	278	28	Th1	th1	NN
cord-263862-zzys31e9	278	29	cells	cell	NNS
cord-263862-zzys31e9	278	30	specific	specific	JJ
cord-263862-zzys31e9	278	31	for	for	IN
cord-263862-zzys31e9	278	32	the	the	DT
cord-263862-zzys31e9	278	33	co	co	NN
cord-263862-zzys31e9	278	34	-	-	JJ
cord-263862-zzys31e9	278	35	administered	administer	VBN
cord-263862-zzys31e9	278	36	protein	protein	NN
cord-263862-zzys31e9	278	37	.	.	.
cord-263862-zzys31e9	279	1	When	when	WRB
cord-263862-zzys31e9	279	2	these	these	DT
cord-263862-zzys31e9	279	3	cells	cell	NNS
cord-263862-zzys31e9	279	4	re	re	VBP
cord-263862-zzys31e9	279	5	-	-	VBP
cord-263862-zzys31e9	279	6	circulate	circulate	VB
cord-263862-zzys31e9	279	7	to	to	IN
cord-263862-zzys31e9	279	8	the	the	DT
cord-263862-zzys31e9	279	9	B	b	NN
cord-263862-zzys31e9	279	10	cell	cell	NN
cord-263862-zzys31e9	279	11	rich	rich	JJ
cord-263862-zzys31e9	279	12	areas	area	NNS
cord-263862-zzys31e9	279	13	of	of	IN
cord-263862-zzys31e9	279	14	the	the	DT
cord-263862-zzys31e9	279	15	spleen	spleen	NNS
cord-263862-zzys31e9	279	16	they	-PRON-	PRP
cord-263862-zzys31e9	279	17	enhance	enhance	VBP
cord-263862-zzys31e9	279	18	isotype	isotype	NN
cord-263862-zzys31e9	279	19	switching	switch	VBG
cord-263862-zzys31e9	279	20	to	to	IN
cord-263862-zzys31e9	279	21	IgG2a	IgG2a	NNP
cord-263862-zzys31e9	279	22	.	.	.
cord-263862-zzys31e9	280	1	Innate	innate	JJ
cord-263862-zzys31e9	280	2	immune	immune	JJ
cord-263862-zzys31e9	280	3	induction	induction	NN
cord-263862-zzys31e9	280	4	of	of	IN
cord-263862-zzys31e9	280	5	the	the	DT
cord-263862-zzys31e9	280	6	adaptive	adaptive	JJ
cord-263862-zzys31e9	280	7	immune	immune	JJ
cord-263862-zzys31e9	280	8	response	response	NN
cord-263862-zzys31e9	280	9	Towards	towards	IN
cord-263862-zzys31e9	280	10	the	the	DT
cord-263862-zzys31e9	280	11	rational	rational	JJ
cord-263862-zzys31e9	280	12	design	design	NN
cord-263862-zzys31e9	280	13	of	of	IN
cord-263862-zzys31e9	280	14	Th1	th1	NN
cord-263862-zzys31e9	280	15	adjuvants	adjuvant	NNS
cord-263862-zzys31e9	280	16	Immunological	immunological	JJ
cord-263862-zzys31e9	280	17	foundations	foundation	NNS
cord-263862-zzys31e9	280	18	to	to	IN
cord-263862-zzys31e9	280	19	the	the	DT
cord-263862-zzys31e9	280	20	quest	quest	NN
cord-263862-zzys31e9	280	21	for	for	IN
cord-263862-zzys31e9	280	22	new	new	JJ
cord-263862-zzys31e9	280	23	vaccine	vaccine	NN
cord-263862-zzys31e9	280	24	adjuvants	adjuvant	NNS
cord-263862-zzys31e9	280	25	Safety	safety	NN
cord-263862-zzys31e9	280	26	and	and	CC
cord-263862-zzys31e9	280	27	immunogenicity	immunogenicity	NN
cord-263862-zzys31e9	280	28	of	of	IN
cord-263862-zzys31e9	280	29	a	a	DT
cord-263862-zzys31e9	280	30	high	high	RB
cord-263862-zzys31e9	280	31	-	-	HYPH
cord-263862-zzys31e9	280	32	titered	titered	JJ
cord-263862-zzys31e9	280	33	canarypox	canarypox	NN
cord-263862-zzys31e9	280	34	vaccine	vaccine	NN
cord-263862-zzys31e9	280	35	in	in	IN
cord-263862-zzys31e9	280	36	combination	combination	NN
cord-263862-zzys31e9	280	37	with	with	IN
cord-263862-zzys31e9	280	38	rgp120	rgp120	NN
cord-263862-zzys31e9	280	39	in	in	IN
cord-263862-zzys31e9	280	40	a	a	DT
cord-263862-zzys31e9	280	41	diverse	diverse	JJ
cord-263862-zzys31e9	280	42	population	population	NN
cord-263862-zzys31e9	280	43	of	of	IN
cord-263862-zzys31e9	280	44	HIV-1-uninfected	hiv-1-uninfecte	VBN
cord-263862-zzys31e9	280	45	adults	adult	NNS
cord-263862-zzys31e9	280	46	:	:	:
cord-263862-zzys31e9	281	1	AIDS	AIDS	NNP
cord-263862-zzys31e9	281	2	Vaccine	Vaccine	NNP
cord-263862-zzys31e9	281	3	Evaluation	Evaluation	NNP
cord-263862-zzys31e9	281	4	Group	Group	NNP
cord-263862-zzys31e9	281	5	Protocol	Protocol	NNP
cord-263862-zzys31e9	281	6	022A	022A	NNP
cord-263862-zzys31e9	281	7	Safety	safety	NN
cord-263862-zzys31e9	281	8	and	and	CC
cord-263862-zzys31e9	281	9	immunogenicity	immunogenicity	NN
cord-263862-zzys31e9	281	10	of	of	IN
cord-263862-zzys31e9	281	11	an	an	DT
cord-263862-zzys31e9	281	12	HIV	HIV	NNP
cord-263862-zzys31e9	281	13	subtype	subtype	NN
cord-263862-zzys31e9	281	14	B	b	NN
cord-263862-zzys31e9	281	15	and	and	CC
cord-263862-zzys31e9	281	16	E	e	CD
cord-263862-zzys31e9	281	17	prime	prime	JJ
cord-263862-zzys31e9	281	18	-	-	HYPH
cord-263862-zzys31e9	281	19	boost	boost	NN
cord-263862-zzys31e9	281	20	vaccine	vaccine	NN
cord-263862-zzys31e9	281	21	combination	combination	NN
cord-263862-zzys31e9	281	22	in	in	IN
cord-263862-zzys31e9	281	23	HIV	HIV	NNP
cord-263862-zzys31e9	281	24	-	-	HYPH
cord-263862-zzys31e9	281	25	negative	negative	JJ
cord-263862-zzys31e9	281	26	Thai	thai	JJ
cord-263862-zzys31e9	281	27	adults	adult	NNS
cord-263862-zzys31e9	281	28	Recombinant	recombinant	JJ
cord-263862-zzys31e9	281	29	viruses	virus	NNS
cord-263862-zzys31e9	281	30	as	as	IN
cord-263862-zzys31e9	281	31	a	a	DT
cord-263862-zzys31e9	281	32	tool	tool	NN
cord-263862-zzys31e9	281	33	for	for	IN
cord-263862-zzys31e9	281	34	therapeutic	therapeutic	JJ
cord-263862-zzys31e9	281	35	vaccination	vaccination	NN
cord-263862-zzys31e9	281	36	against	against	IN
cord-263862-zzys31e9	281	37	human	human	JJ
cord-263862-zzys31e9	281	38	cancers	cancer	NNS
cord-263862-zzys31e9	281	39	Modulation	modulation	NN
cord-263862-zzys31e9	281	40	of	of	IN
cord-263862-zzys31e9	281	41	the	the	DT
cord-263862-zzys31e9	281	42	antibody	antibody	NN
cord-263862-zzys31e9	281	43	response	response	NN
cord-263862-zzys31e9	281	44	to	to	IN
cord-263862-zzys31e9	281	45	the	the	DT
cord-263862-zzys31e9	281	46	HIV	HIV	NNP
cord-263862-zzys31e9	281	47	envelope	envelope	NN
cord-263862-zzys31e9	281	48	subunit	subunit	NN
cord-263862-zzys31e9	281	49	by	by	IN
cord-263862-zzys31e9	281	50	co	co	NN
cord-263862-zzys31e9	281	51	-	-	NN
cord-263862-zzys31e9	281	52	administration	administration	NN
cord-263862-zzys31e9	281	53	of	of	IN
cord-263862-zzys31e9	281	54	infectious	infectious	JJ
cord-263862-zzys31e9	281	55	or	or	CC
cord-263862-zzys31e9	281	56	heat	heat	NN
cord-263862-zzys31e9	281	57	-	-	HYPH
cord-263862-zzys31e9	281	58	inactivated	inactivate	VBN
cord-263862-zzys31e9	281	59	canarypoxvirus	canarypoxvirus	NN
cord-263862-zzys31e9	281	60	(	(	-LRB-
cord-263862-zzys31e9	281	61	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	281	62	)	)	-RRB-
cord-263862-zzys31e9	281	63	preparations	preparation	NNS
cord-263862-zzys31e9	281	64	Novel	Novel	NNP
cord-263862-zzys31e9	281	65	protein	protein	NN
cord-263862-zzys31e9	281	66	and	and	CC
cord-263862-zzys31e9	281	67	poxvirus	poxvirus	NNP
cord-263862-zzys31e9	281	68	-	-	HYPH
cord-263862-zzys31e9	281	69	based	base	VBN
cord-263862-zzys31e9	281	70	vaccine	vaccine	NN
cord-263862-zzys31e9	281	71	combinations	combination	NNS
cord-263862-zzys31e9	281	72	for	for	IN
cord-263862-zzys31e9	281	73	simultaneous	simultaneous	JJ
cord-263862-zzys31e9	281	74	induction	induction	NN
cord-263862-zzys31e9	281	75	of	of	IN
cord-263862-zzys31e9	281	76	humoral	humoral	JJ
cord-263862-zzys31e9	281	77	and	and	CC
cord-263862-zzys31e9	281	78	cell	cell	NN
cord-263862-zzys31e9	281	79	-	-	HYPH
cord-263862-zzys31e9	281	80	mediated	mediate	VBN
cord-263862-zzys31e9	281	81	immunity	immunity	NN
cord-263862-zzys31e9	281	82	Canarypox	Canarypox	NNP
cord-263862-zzys31e9	281	83	virus	virus	NN
cord-263862-zzys31e9	281	84	-	-	HYPH
cord-263862-zzys31e9	281	85	induced	induce	VBN
cord-263862-zzys31e9	281	86	maturation	maturation	NN
cord-263862-zzys31e9	281	87	of	of	IN
cord-263862-zzys31e9	281	88	dendritic	dendritic	JJ
cord-263862-zzys31e9	281	89	cells	cell	NNS
cord-263862-zzys31e9	281	90	is	be	VBZ
cord-263862-zzys31e9	281	91	mediated	mediate	VBN
cord-263862-zzys31e9	281	92	by	by	IN
cord-263862-zzys31e9	281	93	apoptotic	apoptotic	JJ
cord-263862-zzys31e9	281	94	cell	cell	NN
cord-263862-zzys31e9	281	95	death	death	NN
cord-263862-zzys31e9	281	96	and	and	CC
cord-263862-zzys31e9	281	97	tumor	tumor	NN
cord-263862-zzys31e9	281	98	necrosis	necrosis	NN
cord-263862-zzys31e9	281	99	factor	factor	NN
cord-263862-zzys31e9	281	100	alpha	alpha	NN
cord-263862-zzys31e9	281	101	secretion	secretion	NN
cord-263862-zzys31e9	282	1	The	the	DT
cord-263862-zzys31e9	282	2	dialogue	dialogue	NN
cord-263862-zzys31e9	282	3	between	between	IN
cord-263862-zzys31e9	282	4	human	human	JJ
cord-263862-zzys31e9	282	5	natural	natural	JJ
cord-263862-zzys31e9	282	6	killer	killer	NN
cord-263862-zzys31e9	282	7	cells	cell	NNS
cord-263862-zzys31e9	282	8	and	and	CC
cord-263862-zzys31e9	282	9	dendritic	dendritic	JJ
cord-263862-zzys31e9	282	10	cells	cell	NNS
cord-263862-zzys31e9	282	11	Comparative	comparative	JJ
cord-263862-zzys31e9	282	12	studies	study	NNS
cord-263862-zzys31e9	282	13	of	of	IN
cord-263862-zzys31e9	282	14	Avipox	Avipox	NNP
cord-263862-zzys31e9	282	15	-	-	HYPH
cord-263862-zzys31e9	282	16	GM	GM	NNP
cord-263862-zzys31e9	282	17	-	-	HYPH
cord-263862-zzys31e9	282	18	CSF	CSF	NNP
cord-263862-zzys31e9	282	19	versus	versus	IN
cord-263862-zzys31e9	282	20	recombinant	recombinant	JJ
cord-263862-zzys31e9	282	21	GM	GM	NNP
cord-263862-zzys31e9	282	22	-	-	HYPH
cord-263862-zzys31e9	282	23	CSF	csf	NN
cord-263862-zzys31e9	282	24	protein	protein	NN
cord-263862-zzys31e9	282	25	as	as	IN
cord-263862-zzys31e9	282	26	immune	immune	JJ
cord-263862-zzys31e9	282	27	adjuvants	adjuvant	NNS
cord-263862-zzys31e9	282	28	with	with	IN
cord-263862-zzys31e9	282	29	different	different	JJ
cord-263862-zzys31e9	282	30	vaccine	vaccine	NN
cord-263862-zzys31e9	282	31	platforms	platform	NNS
cord-263862-zzys31e9	282	32	Intratumoral	Intratumoral	NNP
cord-263862-zzys31e9	282	33	administration	administration	NN
cord-263862-zzys31e9	282	34	of	of	IN
cord-263862-zzys31e9	282	35	a	a	DT
cord-263862-zzys31e9	282	36	recombinant	recombinant	JJ
cord-263862-zzys31e9	282	37	canarypox	canarypox	NN
cord-263862-zzys31e9	282	38	virus	virus	NN
cord-263862-zzys31e9	282	39	expressing	express	VBG
cord-263862-zzys31e9	282	40	interleukin	interleukin	NN
cord-263862-zzys31e9	282	41	12	12	CD
cord-263862-zzys31e9	282	42	in	in	IN
cord-263862-zzys31e9	282	43	patients	patient	NNS
cord-263862-zzys31e9	282	44	with	with	IN
cord-263862-zzys31e9	282	45	metastatic	metastatic	JJ
cord-263862-zzys31e9	282	46	melanoma	melanoma	NN
cord-263862-zzys31e9	283	1	A	a	DT
cord-263862-zzys31e9	283	2	type	type	NN
cord-263862-zzys31e9	284	1	I	-PRON-	PRP
cord-263862-zzys31e9	284	2	interferon	interferon	VBD
cord-263862-zzys31e9	284	3	autocrine	autocrine	NN
cord-263862-zzys31e9	284	4	-	-	HYPH
cord-263862-zzys31e9	284	5	paracrine	paracrine	NN
cord-263862-zzys31e9	284	6	loop	loop	NN
cord-263862-zzys31e9	284	7	is	be	VBZ
cord-263862-zzys31e9	284	8	involved	involve	VBN
cord-263862-zzys31e9	284	9	in	in	IN
cord-263862-zzys31e9	284	10	Toll	Toll	NNP
cord-263862-zzys31e9	284	11	-	-	HYPH
cord-263862-zzys31e9	284	12	like	like	JJ
cord-263862-zzys31e9	284	13	receptor	receptor	NN
cord-263862-zzys31e9	284	14	-	-	HYPH
cord-263862-zzys31e9	284	15	induced	induce	VBN
cord-263862-zzys31e9	284	16	interleukin-12p70	interleukin-12p70	POS
cord-263862-zzys31e9	284	17	secretion	secretion	NN
cord-263862-zzys31e9	284	18	by	by	IN
cord-263862-zzys31e9	284	19	dendritic	dendritic	JJ
cord-263862-zzys31e9	284	20	cells	cell	NNS
cord-263862-zzys31e9	284	21	Induction	induction	NN
cord-263862-zzys31e9	284	22	and	and	CC
cord-263862-zzys31e9	284	23	regulation	regulation	NN
cord-263862-zzys31e9	284	24	of	of	IN
cord-263862-zzys31e9	284	25	IFNs	ifn	NNS
cord-263862-zzys31e9	284	26	during	during	IN
cord-263862-zzys31e9	284	27	viral	viral	JJ
cord-263862-zzys31e9	284	28	infections	infection	NNS
cord-263862-zzys31e9	284	29	Safety	safety	NN
cord-263862-zzys31e9	284	30	and	and	CC
cord-263862-zzys31e9	284	31	immunogenicity	immunogenicity	NN
cord-263862-zzys31e9	284	32	of	of	IN
cord-263862-zzys31e9	284	33	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	284	34	vCP1452	vcp1452	NN
cord-263862-zzys31e9	284	35	and	and	CC
cord-263862-zzys31e9	284	36	recombiwith	recombiwith	NN
cord-263862-zzys31e9	284	37	prolonged	prolong	VBD
cord-263862-zzys31e9	284	38	highly	highly	RB
cord-263862-zzys31e9	284	39	active	active	JJ
cord-263862-zzys31e9	284	40	antiretroviral	antiretroviral	JJ
cord-263862-zzys31e9	284	41	therapy	therapy	NN
cord-263862-zzys31e9	284	42	Dendritic	dendritic	JJ
cord-263862-zzys31e9	284	43	cell	cell	NN
cord-263862-zzys31e9	284	44	maturation	maturation	NN
cord-263862-zzys31e9	284	45	,	,	,
cord-263862-zzys31e9	284	46	but	but	CC
cord-263862-zzys31e9	284	47	not	not	RB
cord-263862-zzys31e9	284	48	CD8	CD8	NNP
cord-263862-zzys31e9	284	49	+	+	CC
cord-263862-zzys31e9	284	50	T	T	NNP
cord-263862-zzys31e9	284	51	cell	cell	NN
cord-263862-zzys31e9	284	52	induction	induction	NN
cord-263862-zzys31e9	284	53	,	,	,
cord-263862-zzys31e9	284	54	is	be	VBZ
cord-263862-zzys31e9	284	55	dependent	dependent	JJ
cord-263862-zzys31e9	284	56	on	on	IN
cord-263862-zzys31e9	284	57	type	type	NN
cord-263862-zzys31e9	285	1	I	-PRON-	PRP
cord-263862-zzys31e9	285	2	IFN	IFN	NNP
cord-263862-zzys31e9	285	3	signaling	signal	VBG
cord-263862-zzys31e9	285	4	during	during	IN
cord-263862-zzys31e9	285	5	vaccination	vaccination	NN
cord-263862-zzys31e9	285	6	with	with	IN
cord-263862-zzys31e9	285	7	adenovirus	adenovirus	NN
cord-263862-zzys31e9	285	8	vectors	vector	NNS
cord-263862-zzys31e9	286	1	The	the	DT
cord-263862-zzys31e9	286	2	small	small	JJ
cord-263862-zzys31e9	286	3	subset	subset	NN
cord-263862-zzys31e9	286	4	of	of	IN
cord-263862-zzys31e9	286	5	CD56brightCD16-natural	CD56brightCD16-natural	NNP
cord-263862-zzys31e9	286	6	killer	killer	NN
cord-263862-zzys31e9	286	7	cells	cell	NNS
cord-263862-zzys31e9	286	8	is	be	VBZ
cord-263862-zzys31e9	286	9	selectively	selectively	RB
cord-263862-zzys31e9	286	10	responsible	responsible	JJ
cord-263862-zzys31e9	286	11	for	for	IN
cord-263862-zzys31e9	286	12	both	both	DT
cord-263862-zzys31e9	286	13	cell	cell	NN
cord-263862-zzys31e9	286	14	proliferation	proliferation	NN
cord-263862-zzys31e9	286	15	and	and	CC
cord-263862-zzys31e9	286	16	interferongamma	interferongamma	JJ
cord-263862-zzys31e9	286	17	production	production	NN
cord-263862-zzys31e9	286	18	upon	upon	IN
cord-263862-zzys31e9	286	19	interaction	interaction	NN
cord-263862-zzys31e9	286	20	with	with	IN
cord-263862-zzys31e9	286	21	dendritic	dendritic	JJ
cord-263862-zzys31e9	286	22	cells	cell	NNS
cord-263862-zzys31e9	286	23	Comparative	comparative	JJ
cord-263862-zzys31e9	286	24	analysis	analysis	NN
cord-263862-zzys31e9	286	25	of	of	IN
cord-263862-zzys31e9	286	26	tropism	tropism	NN
cord-263862-zzys31e9	286	27	between	between	IN
cord-263862-zzys31e9	286	28	canarypox	canarypox	NN
cord-263862-zzys31e9	286	29	(	(	-LRB-
cord-263862-zzys31e9	286	30	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	286	31	)	)	-RRB-
cord-263862-zzys31e9	286	32	and	and	CC
cord-263862-zzys31e9	286	33	vaccinia	vaccinia	NN
cord-263862-zzys31e9	286	34	viruses	virus	NNS
cord-263862-zzys31e9	286	35	reveals	reveal	VBZ
cord-263862-zzys31e9	286	36	a	a	DT
cord-263862-zzys31e9	286	37	more	more	RBR
cord-263862-zzys31e9	286	38	restricted	restricted	JJ
cord-263862-zzys31e9	286	39	and	and	CC
cord-263862-zzys31e9	286	40	preferential	preferential	JJ
cord-263862-zzys31e9	286	41	tropism	tropism	NN
cord-263862-zzys31e9	286	42	of	of	IN
cord-263862-zzys31e9	286	43	ALVAC	ALVAC	NNP
cord-263862-zzys31e9	286	44	for	for	IN
cord-263862-zzys31e9	286	45	human	human	JJ
cord-263862-zzys31e9	286	46	cells	cell	NNS
cord-263862-zzys31e9	286	47	of	of	IN
cord-263862-zzys31e9	286	48	the	the	DT
cord-263862-zzys31e9	286	49	monocytic	monocytic	JJ
cord-263862-zzys31e9	286	50	lineage	lineage	NN
cord-263862-zzys31e9	286	51	TLRdependent	tlrdependent	NN
cord-263862-zzys31e9	286	52	activation	activation	NN
cord-263862-zzys31e9	286	53	stimuli	stimulus	NNS
cord-263862-zzys31e9	286	54	associated	associate	VBN
cord-263862-zzys31e9	286	55	with	with	IN
cord-263862-zzys31e9	286	56	Th1	th1	NN
cord-263862-zzys31e9	286	57	responses	response	NNS
cord-263862-zzys31e9	286	58	confer	confer	VBP
cord-263862-zzys31e9	286	59	NK	NK	NNP
cord-263862-zzys31e9	286	60	cell	cell	NN
cord-263862-zzys31e9	286	61	stimulatory	stimulatory	JJ
cord-263862-zzys31e9	286	62	capacity	capacity	NN
cord-263862-zzys31e9	286	63	to	to	TO
cord-263862-zzys31e9	286	64	mouse	mouse	VB
cord-263862-zzys31e9	286	65	dendritic	dendritic	JJ
cord-263862-zzys31e9	286	66	cells	cell	NNS
cord-263862-zzys31e9	286	67	CpG	CpG	NNP
cord-263862-zzys31e9	286	68	and	and	CC
cord-263862-zzys31e9	286	69	double	double	RB
cord-263862-zzys31e9	286	70	-	-	HYPH
cord-263862-zzys31e9	286	71	stranded	strand	VBN
cord-263862-zzys31e9	286	72	RNA	RNA	NNP
cord-263862-zzys31e9	286	73	trigger	trigger	NN
cord-263862-zzys31e9	286	74	human	human	JJ
cord-263862-zzys31e9	286	75	NK	NK	NNP
cord-263862-zzys31e9	286	76	cells	cell	NNS
cord-263862-zzys31e9	286	77	by	by	IN
cord-263862-zzys31e9	286	78	Toll	toll	NN
cord-263862-zzys31e9	286	79	-	-	HYPH
cord-263862-zzys31e9	286	80	like	like	JJ
cord-263862-zzys31e9	286	81	receptors	receptor	NNS
cord-263862-zzys31e9	286	82	:	:	:
cord-263862-zzys31e9	286	83	induction	induction	NN
cord-263862-zzys31e9	286	84	of	of	IN
cord-263862-zzys31e9	286	85	cytokine	cytokine	NN
cord-263862-zzys31e9	286	86	release	release	NN
cord-263862-zzys31e9	286	87	and	and	CC
cord-263862-zzys31e9	286	88	cytotoxicity	cytotoxicity	NN
cord-263862-zzys31e9	286	89	against	against	IN
cord-263862-zzys31e9	286	90	tumors	tumor	NNS
cord-263862-zzys31e9	286	91	and	and	CC
cord-263862-zzys31e9	286	92	dendritic	dendritic	JJ
cord-263862-zzys31e9	286	93	cells	cell	NNS
cord-263862-zzys31e9	287	1	TLR7/8-mediated	tlr7/8-mediated	CD
cord-263862-zzys31e9	287	2	activation	activation	NN
cord-263862-zzys31e9	287	3	of	of	IN
cord-263862-zzys31e9	287	4	human	human	JJ
cord-263862-zzys31e9	287	5	NK	NK	NNP
cord-263862-zzys31e9	287	6	cells	cell	NNS
cord-263862-zzys31e9	287	7	results	result	NNS
cord-263862-zzys31e9	287	8	in	in	IN
cord-263862-zzys31e9	287	9	accessory	accessory	JJ
cord-263862-zzys31e9	287	10	cell	cell	NN
cord-263862-zzys31e9	287	11	-	-	HYPH
cord-263862-zzys31e9	287	12	dependent	dependent	JJ
cord-263862-zzys31e9	287	13	IFN	IFN	NNP
cord-263862-zzys31e9	287	14	-	-	HYPH
cord-263862-zzys31e9	287	15	gamma	gamma	NN
cord-263862-zzys31e9	287	16	production	production	NN
cord-263862-zzys31e9	287	17	Neutralization	neutralization	NN
cord-263862-zzys31e9	287	18	of	of	IN
cord-263862-zzys31e9	287	19	the	the	DT
cord-263862-zzys31e9	287	20	chemokine	chemokine	NN
cord-263862-zzys31e9	288	1	CXCL10	CXCL10	NNP
cord-263862-zzys31e9	288	2	reduces	reduce	VBZ
cord-263862-zzys31e9	288	3	inflammatory	inflammatory	JJ
cord-263862-zzys31e9	288	4	cell	cell	NN
cord-263862-zzys31e9	288	5	invasion	invasion	NN
cord-263862-zzys31e9	288	6	and	and	CC
cord-263862-zzys31e9	288	7	demyelination	demyelination	NN
cord-263862-zzys31e9	288	8	and	and	CC
cord-263862-zzys31e9	288	9	improves	improve	VBZ
cord-263862-zzys31e9	288	10	neurological	neurological	JJ
cord-263862-zzys31e9	288	11	function	function	NN
cord-263862-zzys31e9	288	12	in	in	IN
cord-263862-zzys31e9	288	13	a	a	DT
cord-263862-zzys31e9	288	14	viral	viral	JJ
cord-263862-zzys31e9	288	15	model	model	NN
cord-263862-zzys31e9	288	16	of	of	IN
cord-263862-zzys31e9	288	17	multiple	multiple	JJ
cord-263862-zzys31e9	288	18	sclerosis	sclerosis	NN
cord-263862-zzys31e9	288	19	CXC	CXC	NNP
cord-263862-zzys31e9	288	20	chemokine	chemokine	NN
cord-263862-zzys31e9	288	21	ligand	ligand	NN
cord-263862-zzys31e9	288	22	10	10	CD
cord-263862-zzys31e9	288	23	controls	control	NNS
cord-263862-zzys31e9	288	24	viral	viral	JJ
cord-263862-zzys31e9	288	25	infection	infection	NN
cord-263862-zzys31e9	288	26	in	in	IN
cord-263862-zzys31e9	288	27	the	the	DT
cord-263862-zzys31e9	288	28	central	central	JJ
cord-263862-zzys31e9	288	29	nervous	nervous	JJ
cord-263862-zzys31e9	288	30	system	system	NN
cord-263862-zzys31e9	288	31	:	:	:
cord-263862-zzys31e9	288	32	evidence	evidence	NN
cord-263862-zzys31e9	288	33	for	for	IN
cord-263862-zzys31e9	288	34	a	a	DT
cord-263862-zzys31e9	288	35	role	role	NN
cord-263862-zzys31e9	288	36	in	in	IN
cord-263862-zzys31e9	288	37	innate	innate	JJ
cord-263862-zzys31e9	288	38	immune	immune	JJ
cord-263862-zzys31e9	288	39	response	response	NN
cord-263862-zzys31e9	288	40	through	through	IN
cord-263862-zzys31e9	288	41	recruitment	recruitment	NN
cord-263862-zzys31e9	288	42	and	and	CC
cord-263862-zzys31e9	288	43	activation	activation	NN
cord-263862-zzys31e9	288	44	of	of	IN
cord-263862-zzys31e9	288	45	natural	natural	JJ
cord-263862-zzys31e9	288	46	killer	killer	NN
cord-263862-zzys31e9	288	47	cells	cell	NNS
cord-263862-zzys31e9	288	48	IFNgamma	IFNgamma	NNP
cord-263862-zzys31e9	288	49	-	-	HYPH
cord-263862-zzys31e9	288	50	inducible	inducible	JJ
cord-263862-zzys31e9	288	51	protein	protein	NN
cord-263862-zzys31e9	288	52	10	10	CD
cord-263862-zzys31e9	288	53	(	(	-LRB-
cord-263862-zzys31e9	289	1	IP-10	IP-10	NNP
cord-263862-zzys31e9	289	2	;	;	.
cord-263862-zzys31e9	289	3	CXCL10)-deficient	CXCL10)-deficient	NNP
cord-263862-zzys31e9	290	1	mice	mouse	NNS
cord-263862-zzys31e9	290	2	reveal	reveal	VBP
cord-263862-zzys31e9	290	3	a	a	DT
cord-263862-zzys31e9	290	4	role	role	NN
cord-263862-zzys31e9	290	5	for	for	IN
cord-263862-zzys31e9	290	6	IP-10	IP-10	NNP
cord-263862-zzys31e9	290	7	in	in	IN
cord-263862-zzys31e9	290	8	effector	effector	JJ
cord-263862-zzys31e9	290	9	T	T	NNP
cord-263862-zzys31e9	290	10	cell	cell	NN
cord-263862-zzys31e9	290	11	generation	generation	NN
cord-263862-zzys31e9	290	12	and	and	CC
cord-263862-zzys31e9	290	13	trafficking	traffic	VBG
cord-263862-zzys31e9	290	14	Monocyte	Monocyte	NNP
cord-263862-zzys31e9	290	15	chemoattractant	chemoattractant	NN
cord-263862-zzys31e9	290	16	protein-1	protein-1	NNP
cord-263862-zzys31e9	290	17	and	and	CC
cord-263862-zzys31e9	290	18	CCR2	CCR2	NNP
cord-263862-zzys31e9	290	19	interactions	interaction	NNS
cord-263862-zzys31e9	290	20	are	be	VBP
cord-263862-zzys31e9	290	21	required	require	VBN
cord-263862-zzys31e9	290	22	for	for	IN
cord-263862-zzys31e9	290	23	IFNalpha	ifnalpha	NN
cord-263862-zzys31e9	290	24	/	/	SYM
cord-263862-zzys31e9	290	25	beta	beta	NN
cord-263862-zzys31e9	290	26	-	-	HYPH
cord-263862-zzys31e9	290	27	induced	induce	VBN
cord-263862-zzys31e9	290	28	inflammatory	inflammatory	JJ
cord-263862-zzys31e9	290	29	responses	response	NNS
cord-263862-zzys31e9	290	30	and	and	CC
cord-263862-zzys31e9	290	31	antiviral	antiviral	JJ
cord-263862-zzys31e9	290	32	defense	defense	NN
cord-263862-zzys31e9	290	33	in	in	IN
cord-263862-zzys31e9	290	34	liver	liver	NN