id	sid	tid	token	lemma	pos
cord-023585-n3lr9z3u	1	1	key	key	JJ
cord-023585-n3lr9z3u	1	2	:	:	:
cord-023585-n3lr9z3u	1	3	cord-023585-n3lr9z3u	cord-023585-n3lr9z3u	NNS
cord-023585-n3lr9z3u	1	4	authors	author	NNS
cord-023585-n3lr9z3u	1	5	:	:	:
cord-023585-n3lr9z3u	1	6	Phillpotts	Phillpotts	NNP
cord-023585-n3lr9z3u	1	7	,	,	,
cord-023585-n3lr9z3u	1	8	Robert	Robert	NNP
cord-023585-n3lr9z3u	1	9	title	title	NN
cord-023585-n3lr9z3u	1	10	:	:	:
cord-023585-n3lr9z3u	1	11	Interferon	interferon	NN
cord-023585-n3lr9z3u	1	12	prophylaxis	prophylaxis	NN
cord-023585-n3lr9z3u	1	13	of	of	IN
cord-023585-n3lr9z3u	1	14	the	the	DT
cord-023585-n3lr9z3u	1	15	common	common	JJ
cord-023585-n3lr9z3u	1	16	cold	cold	JJ
cord-023585-n3lr9z3u	1	17	date	date	NN
cord-023585-n3lr9z3u	1	18	:	:	:
cord-023585-n3lr9z3u	1	19	2003	2003	CD
cord-023585-n3lr9z3u	1	20	-	-	SYM
cord-023585-n3lr9z3u	1	21	01	01	CD
cord-023585-n3lr9z3u	1	22	-	-	HYPH
cord-023585-n3lr9z3u	1	23	06	06	CD
cord-023585-n3lr9z3u	1	24	journal	journal	NN
cord-023585-n3lr9z3u	1	25	:	:	:
cord-023585-n3lr9z3u	2	1	Trends	Trends	NNPS
cord-023585-n3lr9z3u	2	2	Pharmacol	Pharmacol	NNP
cord-023585-n3lr9z3u	2	3	Sci	Sci	NNP
cord-023585-n3lr9z3u	2	4	DOI	DOI	NNP
cord-023585-n3lr9z3u	3	1	:	:	:
cord-023585-n3lr9z3u	3	2	10.1016/0165	10.1016/0165	CD
cord-023585-n3lr9z3u	3	3	-	-	HYPH
cord-023585-n3lr9z3u	3	4	6147(84)90509	6147(84)90509	CD
cord-023585-n3lr9z3u	3	5	-	-	SYM
cord-023585-n3lr9z3u	3	6	1	1	CD
cord-023585-n3lr9z3u	3	7	sha	sha	NN
cord-023585-n3lr9z3u	3	8	:	:	:
cord-023585-n3lr9z3u	4	1	b21aca731b8f0115e51fe86c4fba9d30364628c0	b21aca731b8f0115e51fe86c4fba9d30364628c0	NNP
cord-023585-n3lr9z3u	4	2	doc_id	doc_id	CD
cord-023585-n3lr9z3u	4	3	:	:	:
cord-023585-n3lr9z3u	4	4	23585	23585	CD
cord-023585-n3lr9z3u	4	5	cord_uid	cord_uid	NNS
cord-023585-n3lr9z3u	4	6	:	:	:
cord-023585-n3lr9z3u	4	7	n3lr9z3u	n3lr9z3u	NNS
cord-023585-n3lr9z3u	5	1	Interferon	Interferon	NNP
cord-023585-n3lr9z3u	5	2	is	be	VBZ
cord-023585-n3lr9z3u	5	3	a	a	DT
cord-023585-n3lr9z3u	5	4	potential	potential	JJ
cord-023585-n3lr9z3u	5	5	prophylactic	prophylactic	JJ
cord-023585-n3lr9z3u	5	6	agent	agent	NN
cord-023585-n3lr9z3u	5	7	for	for	IN
cord-023585-n3lr9z3u	5	8	the	the	DT
cord-023585-n3lr9z3u	5	9	common	common	JJ
cord-023585-n3lr9z3u	5	10	cold	cold	NN
cord-023585-n3lr9z3u	5	11	.	.	.
cord-023585-n3lr9z3u	6	1	But	but	CC
cord-023585-n3lr9z3u	6	2	there	there	EX
cord-023585-n3lr9z3u	6	3	are	be	VBP
cord-023585-n3lr9z3u	6	4	problems	problem	NNS
cord-023585-n3lr9z3u	6	5	.	.	.
cord-023585-n3lr9z3u	7	1	The	the	DT
cord-023585-n3lr9z3u	7	2	present	present	JJ
cord-023585-n3lr9z3u	7	3	levels	level	NNS
cord-023585-n3lr9z3u	7	4	of	of	IN
cord-023585-n3lr9z3u	7	5	side	side	NN
cord-023585-n3lr9z3u	7	6	-	-	HYPH
cord-023585-n3lr9z3u	7	7	effects	effect	NNS
cord-023585-n3lr9z3u	7	8	that	that	WDT
cord-023585-n3lr9z3u	7	9	have	have	VBP
cord-023585-n3lr9z3u	7	10	been	be	VBN
cord-023585-n3lr9z3u	7	11	observed	observe	VBN
cord-023585-n3lr9z3u	7	12	do	do	VBP
cord-023585-n3lr9z3u	7	13	n't	not	RB
cord-023585-n3lr9z3u	7	14	justify	justify	VB
cord-023585-n3lr9z3u	7	15	its	-PRON-	PRP$
cord-023585-n3lr9z3u	7	16	use	use	NN
cord-023585-n3lr9z3u	7	17	in	in	IN
cord-023585-n3lr9z3u	7	18	the	the	DT
cord-023585-n3lr9z3u	7	19	long	long	JJ
cord-023585-n3lr9z3u	7	20	term	term	NN
cord-023585-n3lr9z3u	7	21	.	.	.
cord-023585-n3lr9z3u	8	1	Robert	Robert	NNP
cord-023585-n3lr9z3u	8	2	Phillpotts	Phillpotts	NNP
cord-023585-n3lr9z3u	8	3	describes	describe	VBZ
cord-023585-n3lr9z3u	8	4	the	the	DT
cord-023585-n3lr9z3u	8	5	mechanism	mechanism	NN
cord-023585-n3lr9z3u	8	6	of	of	IN
cord-023585-n3lr9z3u	8	7	interferon	interferon	NN
cord-023585-n3lr9z3u	8	8	action	action	NN
cord-023585-n3lr9z3u	8	9	and	and	CC
cord-023585-n3lr9z3u	8	10	the	the	DT
cord-023585-n3lr9z3u	8	11	future	future	JJ
cord-023585-n3lr9z3u	8	12	hopes	hope	NNS
cord-023585-n3lr9z3u	8	13	and	and	CC
cord-023585-n3lr9z3u	8	14	developments	development	NNS
cord-023585-n3lr9z3u	8	15	for	for	IN
cord-023585-n3lr9z3u	8	16	its	-PRON-	PRP$
cord-023585-n3lr9z3u	8	17	use	use	NN
cord-023585-n3lr9z3u	8	18	in	in	IN
cord-023585-n3lr9z3u	8	19	preventing	prevent	VBG
cord-023585-n3lr9z3u	8	20	colds	cold	NNS
cord-023585-n3lr9z3u	8	21	.	.	.
cord-023585-n3lr9z3u	9	1	MRC	MRC	NNP
cord-023585-n3lr9z3u	9	2	Common	Common	NNP
cord-023585-n3lr9z3u	9	3	Cold	Cold	NNP
cord-023585-n3lr9z3u	9	4	Unit	Unit	NNP
cord-023585-n3lr9z3u	9	5	,	,	,
cord-023585-n3lr9z3u	9	6	Coombe	Coombe	NNP
cord-023585-n3lr9z3u	9	7	Road	Road	NNP
cord-023585-n3lr9z3u	9	8	,	,	,
cord-023585-n3lr9z3u	9	9	Solisbuty	Solisbuty	NNP
cord-023585-n3lr9z3u	9	10	,	,	,
cord-023585-n3lr9z3u	9	11	Wil	Wil	NNP
cord-023585-n3lr9z3u	9	12	~	~	NFP
cord-023585-n3lr9z3u	9	13	chire	chire	NNP
cord-023585-n3lr9z3u	9	14	SP2	SP2	NNP
cord-023585-n3lr9z3u	9	15	8BW	8BW	NNP
cord-023585-n3lr9z3u	9	16	,	,	,
cord-023585-n3lr9z3u	9	17	UK	UK	NNP
cord-023585-n3lr9z3u	10	1	,	,	,
cord-023585-n3lr9z3u	10	2	Interferon	Interferon	NNP
cord-023585-n3lr9z3u	10	3	is	be	VBZ
cord-023585-n3lr9z3u	10	4	a	a	DT
cord-023585-n3lr9z3u	10	5	potential	potential	JJ
cord-023585-n3lr9z3u	10	6	prophylactic	prophylactic	JJ
cord-023585-n3lr9z3u	10	7	agent	agent	NN
cord-023585-n3lr9z3u	10	8	for	for	IN
cord-023585-n3lr9z3u	10	9	the	the	DT
cord-023585-n3lr9z3u	10	10	common	common	JJ
cord-023585-n3lr9z3u	10	11	cold	cold	NN
cord-023585-n3lr9z3u	10	12	.	.	.
cord-023585-n3lr9z3u	11	1	But	but	CC
cord-023585-n3lr9z3u	11	2	there	there	EX
cord-023585-n3lr9z3u	11	3	are	be	VBP
cord-023585-n3lr9z3u	11	4	problems	problem	NNS
cord-023585-n3lr9z3u	11	5	.	.	.
cord-023585-n3lr9z3u	12	1	The	the	DT
cord-023585-n3lr9z3u	12	2	present	present	JJ
cord-023585-n3lr9z3u	12	3	levels	level	NNS
cord-023585-n3lr9z3u	12	4	of	of	IN
cord-023585-n3lr9z3u	12	5	side	side	NN
cord-023585-n3lr9z3u	12	6	-	-	HYPH
cord-023585-n3lr9z3u	12	7	effects	effect	NNS
cord-023585-n3lr9z3u	12	8	that	that	WDT
cord-023585-n3lr9z3u	12	9	have	have	VBP
cord-023585-n3lr9z3u	12	10	been	be	VBN
cord-023585-n3lr9z3u	12	11	observed	observe	VBN
cord-023585-n3lr9z3u	12	12	do	do	VBP
cord-023585-n3lr9z3u	12	13	n't	not	RB
cord-023585-n3lr9z3u	12	14	justify	justify	VB
cord-023585-n3lr9z3u	12	15	its	-PRON-	PRP$
cord-023585-n3lr9z3u	12	16	use	use	NN
cord-023585-n3lr9z3u	12	17	in	in	IN
cord-023585-n3lr9z3u	12	18	the	the	DT
cord-023585-n3lr9z3u	12	19	long	long	JJ
cord-023585-n3lr9z3u	12	20	term	term	NN
cord-023585-n3lr9z3u	12	21	.	.	.
cord-023585-n3lr9z3u	13	1	l~'obert	l~'obert	NNP
cord-023585-n3lr9z3u	14	1	Phillpotts	Phillpotts	NNP
cord-023585-n3lr9z3u	15	1	describe~	describe~	NNP
cord-023585-n3lr9z3u	16	1	the	the	DT
cord-023585-n3lr9z3u	16	2	mechanism	mechanism	NN
cord-023585-n3lr9z3u	16	3	of	of	IN
cord-023585-n3lr9z3u	16	4	interferon	interferon	NN
cord-023585-n3lr9z3u	16	5	action	action	NN
cord-023585-n3lr9z3u	16	6	and	and	CC
cord-023585-n3lr9z3u	16	7	the	the	DT
cord-023585-n3lr9z3u	16	8	future	future	JJ
cord-023585-n3lr9z3u	16	9	hopes	hope	NNS
cord-023585-n3lr9z3u	16	10	and	and	CC
cord-023585-n3lr9z3u	16	11	developments	development	NNS
cord-023585-n3lr9z3u	16	12	for	for	IN
cord-023585-n3lr9z3u	16	13	its	-PRON-	PRP$
cord-023585-n3lr9z3u	16	14	use	use	NN
cord-023585-n3lr9z3u	16	15	in	in	IN
cord-023585-n3lr9z3u	16	16	preventing	prevent	VBG
cord-023585-n3lr9z3u	16	17	colds	cold	NNS
cord-023585-n3lr9z3u	16	18	.	.	.
cord-023585-n3lr9z3u	17	1	Interferon	Interferon	NNP
cord-023585-n3lr9z3u	17	2	appears	appear	VBZ
cord-023585-n3lr9z3u	17	3	to	to	TO
cord-023585-n3lr9z3u	17	4	be	be	VB
cord-023585-n3lr9z3u	17	5	the	the	DT
cord-023585-n3lr9z3u	17	6	ideal	ideal	JJ
cord-023585-n3lr9z3u	17	7	antiviral	antiviral	JJ
cord-023585-n3lr9z3u	17	8	drug	drug	NN
cord-023585-n3lr9z3u	17	9	for	for	IN
cord-023585-n3lr9z3u	17	10	use	use	NN
cord-023585-n3lr9z3u	17	11	in	in	IN
cord-023585-n3lr9z3u	17	12	preventing	prevent	VBG
cord-023585-n3lr9z3u	17	13	colds	cold	NNS
cord-023585-n3lr9z3u	17	14	;	;	:
cord-023585-n3lr9z3u	17	15	it	-PRON-	PRP
cord-023585-n3lr9z3u	17	16	is	be	VBZ
cord-023585-n3lr9z3u	17	17	extremely	extremely	RB
cord-023585-n3lr9z3u	17	18	potent	potent	JJ
cord-023585-n3lr9z3u	17	19	,	,	,
cord-023585-n3lr9z3u	17	20	and	and	CC
cord-023585-n3lr9z3u	17	21	active	active	JJ
cord-023585-n3lr9z3u	17	22	against	against	IN
cord-023585-n3lr9z3u	17	23	a	a	DT
cord-023585-n3lr9z3u	17	24	wide	wide	JJ
cord-023585-n3lr9z3u	17	25	range	range	NN
cord-023585-n3lr9z3u	17	26	of	of	IN
cord-023585-n3lr9z3u	17	27	viruses	virus	NNS
cord-023585-n3lr9z3u	17	28	.	.	.
cord-023585-n3lr9z3u	18	1	However	however	RB
cord-023585-n3lr9z3u	18	2	,	,	,
cord-023585-n3lr9z3u	18	3	it	-PRON-	PRP
cord-023585-n3lr9z3u	18	4	is	be	VBZ
cord-023585-n3lr9z3u	18	5	too	too	RB
cord-023585-n3lr9z3u	18	6	toxic	toxic	JJ
cord-023585-n3lr9z3u	18	7	for	for	IN
cord-023585-n3lr9z3u	18	8	systemic	systemic	JJ
cord-023585-n3lr9z3u	18	9	use	use	NN
cord-023585-n3lr9z3u	18	10	in	in	IN
cord-023585-n3lr9z3u	18	11	minor	minor	JJ
cord-023585-n3lr9z3u	18	12	respiratory	respiratory	JJ
cord-023585-n3lr9z3u	18	13	illnesses	illness	NNS
cord-023585-n3lr9z3u	18	14	,	,	,
cord-023585-n3lr9z3u	18	15	and	and	CC
cord-023585-n3lr9z3u	18	16	when	when	WRB
cord-023585-n3lr9z3u	18	17	taken	take	VBN
cord-023585-n3lr9z3u	18	18	in	in	IN
cord-023585-n3lr9z3u	18	19	adequate	adequate	JJ
cord-023585-n3lr9z3u	18	20	doses	dose	NNS
cord-023585-n3lr9z3u	19	1	intranasaHy	intranasaHy	.
cord-023585-n3lr9z3u	20	1	it	-PRON-	PRP
cord-023585-n3lr9z3u	20	2	causes	cause	VBZ
cord-023585-n3lr9z3u	20	3	a	a	DT
cord-023585-n3lr9z3u	20	4	mild	mild	JJ
cord-023585-n3lr9z3u	20	5	inflammation	inflammation	NN
cord-023585-n3lr9z3u	20	6	of	of	IN
cord-023585-n3lr9z3u	20	7	the	the	DT
cord-023585-n3lr9z3u	20	8	mucosa	mucosa	NN
cord-023585-n3lr9z3u	20	9	.	.	.
cord-023585-n3lr9z3u	21	1	Current	current	JJ
cord-023585-n3lr9z3u	21	2	research	research	NN
cord-023585-n3lr9z3u	21	3	is	be	VBZ
cord-023585-n3lr9z3u	21	4	directed	direct	VBN
cord-023585-n3lr9z3u	21	5	towards	towards	IN
cord-023585-n3lr9z3u	21	6	overcoming	overcome	VBG
cord-023585-n3lr9z3u	21	7	this	this	DT
cord-023585-n3lr9z3u	21	8	problem	problem	NN
cord-023585-n3lr9z3u	21	9	.	.	.
cord-023585-n3lr9z3u	22	1	For	for	IN
cord-023585-n3lr9z3u	22	2	most	most	JJS
cord-023585-n3lr9z3u	22	3	people	people	NNS
cord-023585-n3lr9z3u	22	4	the	the	DT
cord-023585-n3lr9z3u	22	5	common	common	JJ
cord-023585-n3lr9z3u	22	6	cold	cold	NN
cord-023585-n3lr9z3u	22	7	is	be	VBZ
cord-023585-n3lr9z3u	22	8	a	a	DT
cord-023585-n3lr9z3u	22	9	mild	mild	JJ
cord-023585-n3lr9z3u	22	10	,	,	,
cord-023585-n3lr9z3u	22	11	self	self	NN
cord-023585-n3lr9z3u	22	12	-	-	HYPH
cord-023585-n3lr9z3u	22	13	limiting	limit	VBG
cord-023585-n3lr9z3u	22	14	illness	illness	NN
cord-023585-n3lr9z3u	22	15	.	.	.
cord-023585-n3lr9z3u	23	1	However	however	RB
cord-023585-n3lr9z3u	23	2	,	,	,
cord-023585-n3lr9z3u	23	3	the	the	DT
cord-023585-n3lr9z3u	23	4	high	high	JJ
cord-023585-n3lr9z3u	23	5	incidence	incidence	NN
cord-023585-n3lr9z3u	23	6	of	of	IN
cord-023585-n3lr9z3u	23	7	colds	cold	NNS
cord-023585-n3lr9z3u	23	8	,	,	,
cord-023585-n3lr9z3u	23	9	and	and	CC
cord-023585-n3lr9z3u	23	10	their	-PRON-	PRP$
cord-023585-n3lr9z3u	23	11	ability	ability	NN
cord-023585-n3lr9z3u	23	12	to	to	TO
cord-023585-n3lr9z3u	23	13	cause	cause	VB
cord-023585-n3lr9z3u	23	14	an	an	DT
cord-023585-n3lr9z3u	23	15	exacerbation	exacerbation	NN
cord-023585-n3lr9z3u	23	16	of	of	IN
cord-023585-n3lr9z3u	23	17	chronic	chronic	JJ
cord-023585-n3lr9z3u	23	18	underlying	underlie	VBG
cord-023585-n3lr9z3u	23	19	respiratory	respiratory	JJ
cord-023585-n3lr9z3u	23	20	disease	disease	NN
cord-023585-n3lr9z3u	23	21	leads	lead	VBZ
cord-023585-n3lr9z3u	23	22	to	to	IN
cord-023585-n3lr9z3u	23	23	considerable	considerable	JJ
cord-023585-n3lr9z3u	23	24	morbidity	morbidity	NN
cord-023585-n3lr9z3u	23	25	.	.	.
cord-023585-n3lr9z3u	24	1	Research	research	NN
cord-023585-n3lr9z3u	24	2	has	have	VBZ
cord-023585-n3lr9z3u	24	3	established	establish	VBN
cord-023585-n3lr9z3u	24	4	that	that	IN
cord-023585-n3lr9z3u	24	5	over	over	IN
cord-023585-n3lr9z3u	24	6	200	200	CD
cord-023585-n3lr9z3u	24	7	serologicaily	serologicaily	JJ
cord-023585-n3lr9z3u	24	8	distinct	distinct	JJ
cord-023585-n3lr9z3u	24	9	viruses	virus	NNS
cord-023585-n3lr9z3u	24	10	can	can	MD
cord-023585-n3lr9z3u	24	11	cause	cause	VB
cord-023585-n3lr9z3u	24	12	a	a	DT
cord-023585-n3lr9z3u	24	13	cold	cold	NN
cord-023585-n3lr9z3u	24	14	,	,	,
cord-023585-n3lr9z3u	24	15	and	and	CC
cord-023585-n3lr9z3u	24	16	there	there	EX
cord-023585-n3lr9z3u	24	17	is	be	VBZ
cord-023585-n3lr9z3u	24	18	little	little	JJ
cord-023585-n3lr9z3u	24	19	hope	hope	NN
cord-023585-n3lr9z3u	24	20	that	that	IN
cord-023585-n3lr9z3u	24	21	infectica	infectica	NNP
cord-023585-n3lr9z3u	24	22	can	can	MD
cord-023585-n3lr9z3u	24	23	be	be	VB
cord-023585-n3lr9z3u	24	24	controlled	control	VBN
cord-023585-n3lr9z3u	24	25	by	by	IN
cord-023585-n3lr9z3u	24	26	vaccination	vaccination	NN
cord-023585-n3lr9z3u	24	27	.	.	.
cord-023585-n3lr9z3u	25	1	Therefore	therefore	RB
cord-023585-n3lr9z3u	25	2	control	control	NN
cord-023585-n3lr9z3u	25	3	by	by	IN
cord-023585-n3lr9z3u	25	4	means	mean	NNS
cord-023585-n3lr9z3u	25	5	of	of	IN
cord-023585-n3lr9z3u	25	6	a	a	DT
cord-023585-n3lr9z3u	25	7	broad	broad	JJ
cord-023585-n3lr9z3u	25	8	-	-	HYPH
cord-023585-n3lr9z3u	25	9	spectrmn	spectrmn	NN
cord-023585-n3lr9z3u	25	10	antivizal	antivizal	JJ
cord-023585-n3lr9z3u	25	11	agent	agent	NN
cord-023585-n3lr9z3u	25	12	is	be	VBZ
cord-023585-n3lr9z3u	25	13	the	the	DT
cord-023585-n3lr9z3u	25	14	most	most	RBS
cord-023585-n3lr9z3u	25	15	rational	rational	JJ
cord-023585-n3lr9z3u	25	16	approach	approach	NN
cord-023585-n3lr9z3u	25	17	,	,	,
cord-023585-n3lr9z3u	25	18	and	and	CC
cord-023585-n3lr9z3u	25	19	interferon	interferon	NN
cord-023585-n3lr9z3u	25	20	is	be	VBZ
cord-023585-n3lr9z3u	25	21	without	without	IN
cord-023585-n3lr9z3u	25	22	doubt	doubt	NN
cord-023585-n3lr9z3u	25	23	the	the	DT
cord-023585-n3lr9z3u	25	24	most	most	JJS
cord-023585-n3lr9z3u	25	25	pote	pote	NNP
cord-023585-n3lr9z3u	25	26	=	=	FW
cord-023585-n3lr9z3u	25	27	t	t	NN
cord-023585-n3lr9z3u	25	28	,	,	,
cord-023585-n3lr9z3u	25	29	and	and	CC
cord-023585-n3lr9z3u	25	30	broadly	broadly	RB
cord-023585-n3lr9z3u	25	31	active	active	JJ
cord-023585-n3lr9z3u	25	32	antiviral	antiviral	JJ
cord-023585-n3lr9z3u	25	33	agent	agent	NN
cord-023585-n3lr9z3u	25	34	yet	yet	RB
cord-023585-n3lr9z3u	25	35	discovered	discover	VBN
cord-023585-n3lr9z3u	25	36	.	.	.
cord-023585-n3lr9z3u	26	1	C~	C~	NNP
cord-023585-n3lr9z3u	26	2	course	course	RB
cord-023585-n3lr9z3u	26	3	there	there	EX
cord-023585-n3lr9z3u	26	4	are	be	VBP
cord-023585-n3lr9z3u	26	5	limitations	limitation	NNS
cord-023585-n3lr9z3u	26	6	upon	upon	IN
cord-023585-n3lr9z3u	26	7	the	the	DT
cord-023585-n3lr9z3u	26	8	k	k	XX
cord-023585-n3lr9z3u	27	1	~nd	~nd	NNP
cord-023585-n3lr9z3u	27	2	of	of	IN
cord-023585-n3lr9z3u	27	3	medication	medication	NN
cord-023585-n3lr9z3u	27	4	which	which	WDT
cord-023585-n3lr9z3u	27	5	could	could	MD
cord-023585-n3lr9z3u	27	6	be	be	VB
cord-023585-n3lr9z3u	27	7	used	use	VBN
cord-023585-n3lr9z3u	27	8	to	to	TO
cord-023585-n3lr9z3u	27	9	prevent	prevent	VB
cord-023585-n3lr9z3u	27	10	a	a	DT
cord-023585-n3lr9z3u	27	11	cold	cold	NN
cord-023585-n3lr9z3u	27	12	.	.	.
cord-023585-n3lr9z3u	28	1	For	for	IN
cord-023585-n3lr9z3u	28	2	example	example	NN
cord-023585-n3lr9z3u	28	3	it	-PRON-	PRP
cord-023585-n3lr9z3u	28	4	should	should	MD
cord-023585-n3lr9z3u	28	5	be	be	VB
cord-023585-n3lr9z3u	28	6	cheap	cheap	JJ
cord-023585-n3lr9z3u	28	7	and	and	CC
cord-023585-n3lr9z3u	28	8	easy	easy	JJ
cord-023585-n3lr9z3u	28	9	to	to	TO
cord-023585-n3lr9z3u	28	10	manufacture	manufacture	VB
cord-023585-n3lr9z3u	28	11	,	,	,
cord-023585-n3lr9z3u	28	12	as	as	RB
cord-023585-n3lr9z3u	28	13	well	well	RB
cord-023585-n3lr9z3u	28	14	as	as	IN
cord-023585-n3lr9z3u	28	15	being	be	VBG
cord-023585-n3lr9z3u	28	16	highly	highly	RB
cord-023585-n3lr9z3u	28	17	effective	effective	JJ
cord-023585-n3lr9z3u	28	18	,	,	,
cord-023585-n3lr9z3u	28	19	and	and	CC
cord-023585-n3lr9z3u	28	20	virtually	virtually	RB
cord-023585-n3lr9z3u	28	21	free	free	JJ
cord-023585-n3lr9z3u	28	22	from	from	IN
cord-023585-n3lr9z3u	28	23	side	side	NN
cord-023585-n3lr9z3u	28	24	-	-	HYPH
cord-023585-n3lr9z3u	28	25	effects	effect	NNS
cord-023585-n3lr9z3u	28	26	.	.	.
cord-023585-n3lr9z3u	29	1	I	-PRON-	PRP
cord-023585-n3lr9z3u	30	1	What	what	WP
cord-023585-n3lr9z3u	30	2	is	be	VBZ
cord-023585-n3lr9z3u	30	3	interferen	interferen	NNP
cord-023585-n3lr9z3u	30	4	?	?	.
cord-023585-n3lr9z3u	31	1	I	-PRON-	PRP
cord-023585-n3lr9z3u	32	1	Human	human	JJ
cord-023585-n3lr9z3u	32	2	interferons	interferon	NNS
cord-023585-n3lr9z3u	32	3	(	(	-LRB-
cord-023585-n3lr9z3u	32	4	HulFN	HulFN	NNP
cord-023585-n3lr9z3u	32	5	)	)	-RRB-
cord-023585-n3lr9z3u	32	6	are	be	VBP
cord-023585-n3lr9z3u	32	7	pro-/	pro-/	IN
cord-023585-n3lr9z3u	32	8	teins	tein	NNS
cord-023585-n3lr9z3u	32	9	or	or	CC
cord-023585-n3lr9z3u	32	10	glycoproteins	glycoprotein	NNS
cord-023585-n3lr9z3u	32	11	of	of	IN
cord-023585-n3lr9z3u	32	12	which	which	WDT
cord-023585-n3lr9z3u	32	13	there	there	EX
cord-023585-n3lr9z3u	32	14	are	be	VBP
cord-023585-n3lr9z3u	32	15	:	:	:
cord-023585-n3lr9z3u	32	16	3	3	CD
cord-023585-n3lr9z3u	32	17	principal	principal	JJ
cord-023585-n3lr9z3u	32	18	types	type	NNS
cord-023585-n3lr9z3u	32	19	,	,	,
cord-023585-n3lr9z3u	32	20	a	a	DT
cord-023585-n3lr9z3u	32	21	,	,	,
cord-023585-n3lr9z3u	32	22	13	13	CD
cord-023585-n3lr9z3u	32	23	,	,	,
cord-023585-n3lr9z3u	32	24	and	and	CC
cord-023585-n3lr9z3u	33	1	"	"	``
cord-023585-n3lr9z3u	33	2	y.	y.	NNP
cord-023585-n3lr9z3u	33	3	HulFN	HulFN	NNP
cord-023585-n3lr9z3u	33	4	a	a	NNP
cord-023585-n3lr9z3u	33	5	and	and	CC
cord-023585-n3lr9z3u	33	6	p	p	NN
cord-023585-n3lr9z3u	33	7	:	:	:
cord-023585-n3lr9z3u	34	1	~re	~re	NNP
cord-023585-n3lr9z3u	35	1	both	both	DT
cord-023585-n3lr9z3u	35	2	produced	produce	VBN
cord-023585-n3lr9z3u	35	3	by	by	IN
cord-023585-n3lr9z3u	35	4	cel	cel	NNP
cord-023585-n3lr9z3u	35	5	~	~	NNP
cord-023585-n3lr9z3u	35	6	s	s	XX
cord-023585-n3lr9z3u	35	7	after	after	IN
cord-023585-n3lr9z3u	35	8	exposure	exposure	NN
cord-023585-n3lr9z3u	35	9	to	to	IN
cord-023585-n3lr9z3u	35	10	a	a	DT
cord-023585-n3lr9z3u	35	11	virus	virus	NN
cord-023585-n3lr9z3u	35	12	:	:	:
cord-023585-n3lr9z3u	35	13	WN	WN	NNP
cord-023585-n3lr9z3u	35	14	a	a	DT
cord-023585-n3lr9z3u	35	15	by	by	IN
cord-023585-n3lr9z3u	35	16	"	"	``
cord-023585-n3lr9z3u	35	17	leucocytes	leucocyte	NNS
cord-023585-n3lr9z3u	35	18	and	and	CC
cord-023585-n3lr9z3u	35	19	LFN	LFN	NNP
cord-023585-n3lr9z3u	35	20	13	13	CD
cord-023585-n3lr9z3u	35	21	by	by	IN
cord-023585-n3lr9z3u	35	22	fibroblast	fibroblast	NN
cord-023585-n3lr9z3u	35	23	,	,	,
cord-023585-n3lr9z3u	35	24	,	,	,
cord-023585-n3lr9z3u	35	25	,	,	,
cord-023585-n3lr9z3u	35	26	.	.	.
cord-023585-n3lr9z3u	36	1	HulFN	HulFN	NNP
cord-023585-n3lr9z3u	36	2	~	~	NFP
cord-023585-n3lr9z3u	36	3	is	be	VBZ
cord-023585-n3lr9z3u	36	4	also	also	RB
cord-023585-n3lr9z3u	36	5	produced	produce	VBN
cord-023585-n3lr9z3u	36	6	by	by	IN
cord-023585-n3lr9z3u	36	7	fibroblasts	fibroblast	NNS
cord-023585-n3lr9z3u	36	8	exposed	expose	VBN
cord-023585-n3lr9z3u	36	9	to	to	IN
cord-023585-n3lr9z3u	36	10	double	double	RB
cord-023585-n3lr9z3u	36	11	-	-	HYPH
cord-023585-n3lr9z3u	36	12	stranded	strand	VBN
cord-023585-n3lr9z3u	36	13	RNA	RNA	NNP
cord-023585-n3lr9z3u	36	14	,	,	,
cord-023585-n3lr9z3u	36	15	while	while	IN
cord-023585-n3lr9z3u	36	16	IFN	IFN	NNP
cord-023585-n3lr9z3u	36	17	~/is	~/is	XX
cord-023585-n3lr9z3u	36	18	produced	produce	VBN
cord-023585-n3lr9z3u	36	19	by	by	IN
cord-023585-n3lr9z3u	36	20	lymphocytes	lymphocyte	NNS
cord-023585-n3lr9z3u	36	21	only	only	RB
cord-023585-n3lr9z3u	36	22	in	in	IN
cord-023585-n3lr9z3u	36	23	response	response	NN
cord-023585-n3lr9z3u	36	24	to	to	IN
cord-023585-n3lr9z3u	36	25	an	an	DT
cord-023585-n3lr9z3u	36	26	antigenic	antigenic	JJ
cord-023585-n3lr9z3u	36	27	or	or	CC
cord-023585-n3lr9z3u	36	28	mitogenic	mitogenic	JJ
cord-023585-n3lr9z3u	36	29	stimulus	stimulus	NN
cord-023585-n3lr9z3u	36	30	.	.	.
cord-023585-n3lr9z3u	37	1	Interferons	interferon	NNS
cord-023585-n3lr9z3u	37	2	do	do	VBP
cord-023585-n3lr9z3u	37	3	not	not	RB
cord-023585-n3lr9z3u	37	4	directly	directly	RB
cord-023585-n3lr9z3u	37	5	inhibit	inhibit	VB
cord-023585-n3lr9z3u	37	6	virus	virus	NN
cord-023585-n3lr9z3u	37	7	growth	growth	NN
cord-023585-n3lr9z3u	37	8	,	,	,
cord-023585-n3lr9z3u	37	9	but	but	CC
cord-023585-n3lr9z3u	37	10	exposure	exposure	NN
cord-023585-n3lr9z3u	37	11	of	of	IN
cord-023585-n3lr9z3u	37	12	:	:	:
cord-023585-n3lr9z3u	37	13	mittfected	mittfecte	VBN
cord-023585-n3lr9z3u	37	14	cells	cell	NNS
cord-023585-n3lr9z3u	37	15	to	to	IN
cord-023585-n3lr9z3u	37	16	interferon	interferon	NN
cord-023585-n3lr9z3u	37	17	makes	make	VBZ
cord-023585-n3lr9z3u	37	18	them	-PRON-	PRP
cord-023585-n3lr9z3u	37	19	resistant	resistant	JJ
cord-023585-n3lr9z3u	37	20	to	to	TO
cord-023585-n3lr9z3u	37	21	attack	attack	NN
cord-023585-n3lr9z3u	37	22	by	by	IN
cord-023585-n3lr9z3u	37	23	viruses	virus	NNS
cord-023585-n3lr9z3u	37	24	,	,	,
cord-023585-n3lr9z3u	37	25	interferon	interferon	NN
cord-023585-n3lr9z3u	37	26	is	be	VBZ
cord-023585-n3lr9z3u	37	27	not	not	RB
cord-023585-n3lr9z3u	37	28	internalized	internalize	VBN
cord-023585-n3lr9z3u	37	29	by	by	IN
cord-023585-n3lr9z3u	37	30	cells	cell	NNS
cord-023585-n3lr9z3u	37	31	but	but	CC
cord-023585-n3lr9z3u	37	32	binds	bind	VBZ
cord-023585-n3lr9z3u	37	33	to	to	IN
cord-023585-n3lr9z3u	37	34	cell	cell	NN
cord-023585-n3lr9z3u	37	35	surface	surface	NN
cord-023585-n3lr9z3u	37	36	receptors	receptor	NNS
cord-023585-n3lr9z3u	37	37	(	(	-LRB-
cord-023585-n3lr9z3u	37	38	there	there	EX
cord-023585-n3lr9z3u	37	39	is	be	VBZ
cord-023585-n3lr9z3u	37	40	one	one	CD
cord-023585-n3lr9z3u	37	41	receptor	receptor	NN
cord-023585-n3lr9z3u	37	42	for	for	IN
cord-023585-n3lr9z3u	37	43	IFN	IFN	NNP
cord-023585-n3lr9z3u	37	44	a	a	NNP
cord-023585-n3lr9z3u	37	45	and	and	CC
cord-023585-n3lr9z3u	37	46	[	[	-LRB-
cord-023585-n3lr9z3u	37	47	3	3	CD
cord-023585-n3lr9z3u	37	48	,	,	,
cord-023585-n3lr9z3u	37	49	and	and	CC
cord-023585-n3lr9z3u	37	50	another	another	DT
cord-023585-n3lr9z3u	37	51	receptor	receptor	NN
cord-023585-n3lr9z3u	37	52	for	for	IN
cord-023585-n3lr9z3u	37	53	IFN	IFN	NNP
cord-023585-n3lr9z3u	37	54	y	y	NNP
cord-023585-n3lr9z3u	37	55	)	)	-RRB-
cord-023585-n3lr9z3u	37	56	triggering	trigger	VBG
cord-023585-n3lr9z3u	37	57	off	off	RP
cord-023585-n3lr9z3u	37	58	a	a	DT
cord-023585-n3lr9z3u	37	59	series	series	NN
cord-023585-n3lr9z3u	37	60	of	of	IN
cord-023585-n3lr9z3u	37	61	events	event	NNS
cord-023585-n3lr9z3u	37	62	within	within	IN
cord-023585-n3lr9z3u	37	63	the	the	DT
cord-023585-n3lr9z3u	37	64	cell	cell	NN
cord-023585-n3lr9z3u	37	65	.	.	.
cord-023585-n3lr9z3u	38	1	Multiple	multiple	JJ
cord-023585-n3lr9z3u	38	2	effects	effect	NNS
cord-023585-n3lr9z3u	38	3	have	have	VBP
cord-023585-n3lr9z3u	38	4	been	be	VBN
cord-023585-n3lr9z3u	38	5	observed	observe	VBN
cord-023585-n3lr9z3u	38	6	in	in	IN
cord-023585-n3lr9z3u	38	7	cells	cell	NNS
cord-023585-n3lr9z3u	38	8	,	,	,
cord-023585-n3lr9z3u	38	9	including	include	VBG
cord-023585-n3lr9z3u	38	10	the	the	DT
cord-023585-n3lr9z3u	38	11	inhibition	inhibition	NN
cord-023585-n3lr9z3u	38	12	of	of	IN
cord-023585-n3lr9z3u	38	13	penetration	penetration	NN
cord-023585-n3lr9z3u	38	14	and	and	CC
cord-023585-n3lr9z3u	38	15	maturation	maturation	NN
cord-023585-n3lr9z3u	38	16	of	of	IN
cord-023585-n3lr9z3u	38	17	certain	certain	JJ
cord-023585-n3lr9z3u	38	18	viruses	virus	NNS
cord-023585-n3lr9z3u	38	19	.	.	.
cord-023585-n3lr9z3u	39	1	However	however	RB
cord-023585-n3lr9z3u	39	2	,	,	,
cord-023585-n3lr9z3u	39	3	the	the	DT
cord-023585-n3lr9z3u	39	4	principal	principal	JJ
cord-023585-n3lr9z3u	39	5	effect	effect	NN
cord-023585-n3lr9z3u	39	6	of	of	IN
cord-023585-n3lr9z3u	39	7	interferon	interferon	NN
cord-023585-n3lr9z3u	39	8	treatrnent	treatrnent	NN
cord-023585-n3lr9z3u	39	9	seems	seem	VBZ
cord-023585-n3lr9z3u	39	10	to	to	TO
cord-023585-n3lr9z3u	39	11	be	be	VB
cord-023585-n3lr9z3u	39	12	to	to	TO
cord-023585-n3lr9z3u	39	13	inhibit	inhibit	VB
cord-023585-n3lr9z3u	39	14	viral	viral	JJ
cord-023585-n3lr9z3u	39	15	protein	protein	NN
cord-023585-n3lr9z3u	39	16	synthesis	synthesis	NN
cord-023585-n3lr9z3u	40	1	t.	t.	NNP
cord-023585-n3lr9z3u	40	2	A	a	DT
cord-023585-n3lr9z3u	40	3	system	system	NN
cord-023585-n3lr9z3u	40	4	of	of	IN
cord-023585-n3lr9z3u	40	5	interferoninduced	interferoninduce	VBN
cord-023585-n3lr9z3u	40	6	enzymes	enzyme	NNS
cord-023585-n3lr9z3u	40	7	has	have	VBZ
cord-023585-n3lr9z3u	40	8	been	be	VBN
cord-023585-n3lr9z3u	40	9	described	describe	VBN
cord-023585-n3lr9z3u	40	10	,	,	,
cord-023585-n3lr9z3u	40	11	some	some	DT
cord-023585-n3lr9z3u	40	12	of	of	IN
cord-023585-n3lr9z3u	40	13	which	which	WDT
cord-023585-n3lr9z3u	40	14	are	be	VBP
cord-023585-n3lr9z3u	40	15	activated	activate	VBN
cord-023585-n3lr9z3u	40	16	by	by	IN
cord-023585-n3lr9z3u	40	17	doublestranded	doublestranded	NNP
cord-023585-n3lr9z3u	40	18	RNA	RNA	NNP
cord-023585-n3lr9z3u	40	19	molecules	molecule	NNS
cord-023585-n3lr9z3u	40	20	such	such	JJ
cord-023585-n3lr9z3u	40	21	as	as	IN
cord-023585-n3lr9z3u	40	22	those	those	DT
cord-023585-n3lr9z3u	40	23	produced	produce	VBN
cord-023585-n3lr9z3u	40	24	during	during	IN
cord-023585-n3lr9z3u	40	25	the	the	DT
cord-023585-n3lr9z3u	40	26	replication	replication	NN
cord-023585-n3lr9z3u	40	27	of	of	IN
cord-023585-n3lr9z3u	40	28	RNA	RNA	NNP
cord-023585-n3lr9z3u	40	29	'	'	POS
cord-023585-n3lr9z3u	40	30	druses	druse	NNS
cord-023585-n3lr9z3u	40	31	.	.	.
cord-023585-n3lr9z3u	41	1	The	the	DT
cord-023585-n3lr9z3u	41	2	effect	effect	NN
cord-023585-n3lr9z3u	41	3	of	of	IN
cord-023585-n3lr9z3u	41	4	these	these	DT
cord-023585-n3lr9z3u	41	5	enzymes	enzyme	NNS
cord-023585-n3lr9z3u	41	6	is	be	VBZ
cord-023585-n3lr9z3u	41	7	to	to	TO
cord-023585-n3lr9z3u	41	8	inhibit	inhibit	VB
cord-023585-n3lr9z3u	41	9	the	the	DT
cord-023585-n3lr9z3u	41	10	initiation	initiation	NN
cord-023585-n3lr9z3u	41	11	of	of	IN
cord-023585-n3lr9z3u	41	12	viral	viral	JJ
cord-023585-n3lr9z3u	41	13	protein	protein	NN
cord-023585-n3lr9z3u	41	14	synthesis	synthesis	NN
cord-023585-n3lr9z3u	41	15	,	,	,
cord-023585-n3lr9z3u	41	16	and	and	CC
cord-023585-n3lr9z3u	41	17	to	to	TO
cord-023585-n3lr9z3u	41	18	increase	increase	VB
cord-023585-n3lr9z3u	41	19	the	the	DT
cord-023585-n3lr9z3u	41	20	rate	rate	NN
cord-023585-n3lr9z3u	41	21	at	at	IN
cord-023585-n3lr9z3u	41	22	which	which	WDT
cord-023585-n3lr9z3u	41	23	viral	viral	JJ
cord-023585-n3lr9z3u	41	24	mRNA	mRNA	NNP
cord-023585-n3lr9z3u	41	25	is	be	VBZ
cord-023585-n3lr9z3u	41	26	degraded	degrade	VBN
cord-023585-n3lr9z3u	41	27	within	within	IN
cord-023585-n3lr9z3u	41	28	the	the	DT
cord-023585-n3lr9z3u	41	29	cell	cell	NN
cord-023585-n3lr9z3u	41	30	(	(	-LRB-
cord-023585-n3lr9z3u	41	31	see	see	VB
cord-023585-n3lr9z3u	41	32	Fig	Fig	NNP
cord-023585-n3lr9z3u	41	33	.	.	NNP
cord-023585-n3lr9z3u	41	34	1	1	CD
cord-023585-n3lr9z3u	41	35	)	)	-RRB-
cord-023585-n3lr9z3u	41	36	.	.	.
cord-023585-n3lr9z3u	42	1	Future	future	JJ
cord-023585-n3lr9z3u	42	2	research	research	NN
cord-023585-n3lr9z3u	42	3	will	will	MD
cord-023585-n3lr9z3u	42	4	mldoubtedly	mldoubtedly	RB
cord-023585-n3lr9z3u	42	5	disclose	disclose	VB
cord-023585-n3lr9z3u	42	6	other	other	JJ
cord-023585-n3lr9z3u	42	7	mechanisms	mechanism	NNS
cord-023585-n3lr9z3u	42	8	by	by	IN
cord-023585-n3lr9z3u	42	9	which	which	WDT
cord-023585-n3lr9z3u	42	10	virus	virus	NN
cord-023585-n3lr9z3u	42	11	growth	growth	NN
cord-023585-n3lr9z3u	42	12	is	be	VBZ
cord-023585-n3lr9z3u	42	13	prevented	prevent	VBN
cord-023585-n3lr9z3u	42	14	.	.	.
cord-023585-n3lr9z3u	42	15	"	"	''
cord-023585-n3lr9z3u	43	1	[	[	-LRB-
cord-023585-n3lr9z3u	43	2	here	here	RB
cord-023585-n3lr9z3u	43	3	is	be	VBZ
cord-023585-n3lr9z3u	43	4	already	already	RB
cord-023585-n3lr9z3u	43	5	evidence	evidence	NN
cord-023585-n3lr9z3u	43	6	to	to	TO
cord-023585-n3lr9z3u	43	7	suggest	suggest	VB
cord-023585-n3lr9z3u	43	8	that	that	DT
cord-023585-n3lr9z3u	43	9	I[FN	i[fn	NN
cord-023585-n3lr9z3u	43	10	~	~	NFP
cord-023585-n3lr9z3u	43	11	has	have	VBZ
cord-023585-n3lr9z3u	43	12	a	a	DT
cord-023585-n3lr9z3u	43	13	different	different	JJ
cord-023585-n3lr9z3u	43	14	mechanism	mechanism	NN
cord-023585-n3lr9z3u	43	15	of	of	IN
cord-023585-n3lr9z3u	43	16	~K	~k	CD
cord-023585-n3lr9z3u	43	17	~	~	NFP
cord-023585-n3lr9z3u	43	18	tion	tion	NN
cord-023585-n3lr9z3u	43	19	from	from	IN
cord-023585-n3lr9z3u	43	20	IFNs	IFNs	NNP
cord-023585-n3lr9z3u	43	21	a	a	DT
cord-023585-n3lr9z3u	43	22	and	and	CC
cord-023585-n3lr9z3u	43	23	13	13	CD
cord-023585-n3lr9z3u	43	24	,	,	,
cord-023585-n3lr9z3u	43	25	as	as	IN
cord-023585-n3lr9z3u	43	26	combinations	combination	NNS
cord-023585-n3lr9z3u	43	27	of	of	IN
cord-023585-n3lr9z3u	43	28	IFN	IFN	NNP
cord-023585-n3lr9z3u	43	29	~	~	NFP
cord-023585-n3lr9z3u	43	30	with	with	IN
cord-023585-n3lr9z3u	43	31	IFN	IFN	NNP
cord-023585-n3lr9z3u	43	32	ct	ct	NNP
cord-023585-n3lr9z3u	43	33	or	or	CC
cord-023585-n3lr9z3u	43	34	IFN	IFN	NNP
cord-023585-n3lr9z3u	43	35	13	13	CD
cord-023585-n3lr9z3u	43	36	(	(	-LRB-
cord-023585-n3lr9z3u	44	1	but	but	CC
cord-023585-n3lr9z3u	44	2	not	not	RB
cord-023585-n3lr9z3u	44	3	IFN	IFN	NNP
cord-023585-n3lr9z3u	44	4	a	a	NN
cord-023585-n3lr9z3u	44	5	with	with	IN
cord-023585-n3lr9z3u	44	6	IFN	IFN	NNP
cord-023585-n3lr9z3u	44	7	13	13	CD
cord-023585-n3lr9z3u	44	8	)	)	-RRB-
cord-023585-n3lr9z3u	44	9	exhibit	exhibit	NN
cord-023585-n3lr9z3u	44	10	synergy	synergy	NN
cord-023585-n3lr9z3u	44	11	.	.	.
cord-023585-n3lr9z3u	45	1	The	the	DT
cord-023585-n3lr9z3u	45	2	potency	potency	NN
cord-023585-n3lr9z3u	45	3	of	of	IN
cord-023585-n3lr9z3u	45	4	various	various	JJ
cord-023585-n3lr9z3u	45	5	interferon	interferon	NN
cord-023585-n3lr9z3u	45	6	preparations	preparation	NNS
cord-023585-n3lr9z3u	45	7	may	may	MD
cord-023585-n3lr9z3u	45	8	therefore	therefore	RB
cord-023585-n3lr9z3u	45	9	be	be	VB
cord-023585-n3lr9z3u	45	10	compared	compare	VBN
cord-023585-n3lr9z3u	45	11	in	in	IN
cord-023585-n3lr9z3u	45	12	terms	term	NNS
cord-023585-n3lr9z3u	45	13	of	of	IN
cord-023585-n3lr9z3u	45	14	units	unit	NNS
cord-023585-n3lr9z3u	45	15	of	of	IN
cord-023585-n3lr9z3u	45	16	antiviral	antiviral	JJ
cord-023585-n3lr9z3u	45	17	activity	activity	NN
cord-023585-n3lr9z3u	45	18	.	.	.
cord-023585-n3lr9z3u	46	1	There	there	EX
cord-023585-n3lr9z3u	46	2	is	be	VBZ
cord-023585-n3lr9z3u	46	3	species	specie	NNS
cord-023585-n3lr9z3u	46	4	specificity	specificity	NN
cord-023585-n3lr9z3u	46	5	in	in	IN
cord-023585-n3lr9z3u	46	6	this	this	DT
cord-023585-n3lr9z3u	46	7	process	process	NN
cord-023585-n3lr9z3u	46	8	v	v	NN
cord-023585-n3lr9z3u	46	9	,	,	,
cord-023585-n3lr9z3u	46	10	'	'	''
cord-023585-n3lr9z3u	46	11	11	11	CD
cord-023585-n3lr9z3u	46	12	,	,	,
cord-023585-n3lr9z3u	46	13	while	while	IN
cord-023585-n3lr9z3u	46	14	not	not	RB
cord-023585-n3lr9z3u	46	15	absolute	absolute	JJ
cord-023585-n3lr9z3u	46	16	,	,	,
cord-023585-n3lr9z3u	46	17	means	mean	VBZ
cord-023585-n3lr9z3u	46	18	in	in	IN
cord-023585-n3lr9z3u	46	19	practice	practice	NN
cord-023585-n3lr9z3u	46	20	that	that	IN
cord-023585-n3lr9z3u	46	21	human	human	JJ
cord-023585-n3lr9z3u	46	22	interferon	interferon	NN
cord-023585-n3lr9z3u	46	23	must	must	MD
cord-023585-n3lr9z3u	46	24	be	be	VB
cord-023585-n3lr9z3u	46	25	used	use	VBN
cord-023585-n3lr9z3u	46	26	to	to	TO
cord-023585-n3lr9z3u	46	27	treat	treat	VB
cord-023585-n3lr9z3u	46	28	human	human	JJ
cord-023585-n3lr9z3u	46	29	cells	cell	NNS
cord-023585-n3lr9z3u	46	30	.	.	.
cord-023585-n3lr9z3u	47	1	Human	human	JJ
cord-023585-n3lr9z3u	47	2	interferon	interferon	NN
cord-023585-n3lr9z3u	47	3	may	may	MD
cord-023585-n3lr9z3u	47	4	be	be	VB
cord-023585-n3lr9z3u	47	5	produced	produce	VBN
cord-023585-n3lr9z3u	47	6	from	from	IN
cord-023585-n3lr9z3u	47	7	cells	cell	NNS
cord-023585-n3lr9z3u	47	8	cultured	culture	VBN
cord-023585-n3lr9z3u	47	9	in	in	IN
cord-023585-n3lr9z3u	47	10	vitro	vitro	FW
cord-023585-n3lr9z3u	47	11	.	.	.
cord-023585-n3lr9z3u	48	1	A	a	DT
cord-023585-n3lr9z3u	48	2	partially	partially	RB
cord-023585-n3lr9z3u	48	3	purified	purify	VBN
cord-023585-n3lr9z3u	48	4	human	human	JJ
cord-023585-n3lr9z3u	48	5	leucocyte	leucocyte	NN
cord-023585-n3lr9z3u	48	6	(	(	-LRB-
cord-023585-n3lr9z3u	48	7	a	a	LS
cord-023585-n3lr9z3u	48	8	)	)	-RRB-
cord-023585-n3lr9z3u	49	1	interferon	interferon	NNP
cord-023585-n3lr9z3u	49	2	is	be	VBZ
cord-023585-n3lr9z3u	49	3	produced	produce	VBN
cord-023585-n3lr9z3u	49	4	by	by	IN
cord-023585-n3lr9z3u	49	5	the	the	DT
cord-023585-n3lr9z3u	49	6	Finnish	Finnish	NNP
cord-023585-n3lr9z3u	49	7	Red	Red	NNP
cord-023585-n3lr9z3u	49	8	Cross	Cross	NNP
cord-023585-n3lr9z3u	49	9	from	from	IN
cord-023585-n3lr9z3u	49	10	huffy	huffy	NNP
cord-023585-n3lr9z3u	49	11	coat	coat	NN
cord-023585-n3lr9z3u	49	12	cells	cell	NNS
cord-023585-n3lr9z3u	49	13	(	(	-LRB-
cord-023585-n3lr9z3u	49	14	derived	derive	VBN
cord-023585-n3lr9z3u	49	15	from	from	IN
cord-023585-n3lr9z3u	49	16	blood	blood	NN
cord-023585-n3lr9z3u	49	17	donations	donation	NNS
cord-023585-n3lr9z3u	49	18	)	)	-RRB-
cord-023585-n3lr9z3u	49	19	which	which	WDT
cord-023585-n3lr9z3u	49	20	have	have	VBP
cord-023585-n3lr9z3u	49	21	been	be	VBN
cord-023585-n3lr9z3u	49	22	stimulated	stimulate	VBN
cord-023585-n3lr9z3u	49	23	with	with	IN
cord-023585-n3lr9z3u	49	24	Sendal	Sendal	NNP
cord-023585-n3lr9z3u	49	25	virus	virus	NN
cord-023585-n3lr9z3u	49	26	.	.	.
cord-023585-n3lr9z3u	50	1	However	however	RB
cord-023585-n3lr9z3u	50	2	,	,	,
cord-023585-n3lr9z3u	50	3	this	this	DT
cord-023585-n3lr9z3u	50	4	procedure	procedure	NN
cord-023585-n3lr9z3u	50	5	is	be	VBZ
cord-023585-n3lr9z3u	50	6	expensive	expensive	JJ
cord-023585-n3lr9z3u	50	7	,	,	,
cord-023585-n3lr9z3u	50	8	and	and	CC
cord-023585-n3lr9z3u	50	9	the	the	DT
cord-023585-n3lr9z3u	50	10	amount	amount	NN
cord-023585-n3lr9z3u	50	11	of	of	IN
cord-023585-n3lr9z3u	50	12	interferon	interferon	NN
cord-023585-n3lr9z3u	50	13	which	which	WDT
cord-023585-n3lr9z3u	50	14	can	can	MD
cord-023585-n3lr9z3u	50	15	be	be	VB
cord-023585-n3lr9z3u	50	16	produced	produce	VBN
cord-023585-n3lr9z3u	50	17	is	be	VBZ
cord-023585-n3lr9z3u	50	18	limited	limit	VBN
cord-023585-n3lr9z3u	50	19	by	by	IN
cord-023585-n3lr9z3u	50	20	the	the	DT
cord-023585-n3lr9z3u	50	21	availability	availability	NN
cord-023585-n3lr9z3u	50	22	of	of	IN
cord-023585-n3lr9z3u	50	23	buffy	buffy	NNP
cord-023585-n3lr9z3u	50	24	coat	coat	NN
cord-023585-n3lr9z3u	50	25	cells	cell	NNS
cord-023585-n3lr9z3u	50	26	.	.	.
cord-023585-n3lr9z3u	51	1	More	more	RBR
cord-023585-n3lr9z3u	51	2	recently	recently	RB
cord-023585-n3lr9z3u	51	3	,	,	,
cord-023585-n3lr9z3u	51	4	DNA	dna	NN
cord-023585-n3lr9z3u	51	5	copies	copy	NNS
cord-023585-n3lr9z3u	51	6	of	of	IN
cord-023585-n3lr9z3u	51	7	the	the	DT
cord-023585-n3lr9z3u	51	8	mRNAs	mRNAs	NNPS
cord-023585-n3lr9z3u	51	9	coding	code	VBG
cord-023585-n3lr9z3u	51	10	of	of	IN
cord-023585-n3lr9z3u	51	11	all	all	DT
cord-023585-n3lr9z3u	51	12	3	3	CD
cord-023585-n3lr9z3u	51	13	types	type	NNS
cord-023585-n3lr9z3u	51	14	of	of	IN
cord-023585-n3lr9z3u	51	15	HulFN	HulFN	NNS
cord-023585-n3lr9z3u	51	16	have	have	VBP
cord-023585-n3lr9z3u	51	17	been	be	VBN
cord-023585-n3lr9z3u	51	18	synthesized	synthesize	VBN
cord-023585-n3lr9z3u	51	19	,	,	,
cord-023585-n3lr9z3u	51	20	and	and	CC
cord-023585-n3lr9z3u	51	21	inserted	insert	VBN
cord-023585-n3lr9z3u	51	22	into	into	IN
cord-023585-n3lr9z3u	51	23	plasmid	plasmid	NN
cord-023585-n3lr9z3u	51	24	vectors	vector	NNS
cord-023585-n3lr9z3u	51	25	downstream	downstream	RB
cord-023585-n3lr9z3u	51	26	from	from	IN
cord-023585-n3lr9z3u	51	27	a	a	DT
cord-023585-n3lr9z3u	51	28	suitable	suitable	JJ
cord-023585-n3lr9z3u	51	29	prokaryotic	prokaryotic	JJ
cord-023585-n3lr9z3u	51	30	promoter	promoter	NN
cord-023585-n3lr9z3u	51	31	.	.	.
cord-023585-n3lr9z3u	52	1	Such	such	JJ
cord-023585-n3lr9z3u	52	2	plasmis	plasmis	NN
cord-023585-n3lr9z3u	52	3	are	be	VBP
cord-023585-n3lr9z3u	52	4	introduced	introduce	VBN
cord-023585-n3lr9z3u	52	5	into	into	IN
cord-023585-n3lr9z3u	52	6	bacteria	bacteria	NNS
cord-023585-n3lr9z3u	52	7	by	by	IN
cord-023585-n3lr9z3u	52	8	transfection	transfection	NN
cord-023585-n3lr9z3u	52	9	,	,	,
cord-023585-n3lr9z3u	52	10	where	where	WRB
cord-023585-n3lr9z3u	52	11	they	-PRON-	PRP
cord-023585-n3lr9z3u	52	12	multiply	multiply	VBP
cord-023585-n3lr9z3u	52	13	,	,	,
cord-023585-n3lr9z3u	52	14	and	and	CC
cord-023585-n3lr9z3u	52	15	high	high	JJ
cord-023585-n3lr9z3u	52	16	levels	level	NNS
cord-023585-n3lr9z3u	52	17	of	of	IN
cord-023585-n3lr9z3u	52	18	expression	expression	NN
cord-023585-n3lr9z3u	52	19	of	of	IN
cord-023585-n3lr9z3u	52	20	the	the	DT
cord-023585-n3lr9z3u	52	21	interferon	interferon	NN
cord-023585-n3lr9z3u	52	22	gene	gene	NN
cord-023585-n3lr9z3u	52	23	sequence	sequence	NN
cord-023585-n3lr9z3u	52	24	can	can	MD
cord-023585-n3lr9z3u	52	25	be	be	VB
cord-023585-n3lr9z3u	52	26	cheap	cheap	JJ
cord-023585-n3lr9z3u	52	27	,	,	,
cord-023585-n3lr9z3u	52	28	costs	cost	NNS
cord-023585-n3lr9z3u	52	29	will	will	MD
cord-023585-n3lr9z3u	52	30	undoubtedly	undoubtedly	RB
cord-023585-n3lr9z3u	52	31	be	be	VB
cord-023585-n3lr9z3u	52	32	further	further	RB
cord-023585-n3lr9z3u	52	33	reduced	reduce	VBN
cord-023585-n3lr9z3u	52	34	.	.	.
cord-023585-n3lr9z3u	53	1	intranasal	intranasal	NNP
cord-023585-n3lr9z3u	53	2	interferon	interferon	NN
cord-023585-n3lr9z3u	53	3	prevents	prevent	VBZ
cord-023585-n3lr9z3u	53	4	colds	cold	NNS
cord-023585-n3lr9z3u	53	5	In	in	IN
cord-023585-n3lr9z3u	53	6	an	an	DT
cord-023585-n3lr9z3u	53	7	initial	initial	JJ
cord-023585-n3lr9z3u	53	8	experiment	experiment	NN
cord-023585-n3lr9z3u	53	9	at	at	IN
cord-023585-n3lr9z3u	53	10	the	the	DT
cord-023585-n3lr9z3u	53	11	Common	Common	NNP
cord-023585-n3lr9z3u	53	12	Cold	Cold	NNP
cord-023585-n3lr9z3u	53	13	Unit	Unit	NNP
cord-023585-n3lr9z3u	53	14	in	in	IN
cord-023585-n3lr9z3u	53	15	Wiltshire	Wiltshire	NNP
cord-023585-n3lr9z3u	53	16	,	,	,
cord-023585-n3lr9z3u	53	17	UK	UK	NNP
cord-023585-n3lr9z3u	53	18	,	,	,
cord-023585-n3lr9z3u	53	19	intranasal	intranasal	NNP
cord-023585-n3lr9z3u	53	20	administration	administration	NN
cord-023585-n3lr9z3u	53	21	of	of	IN
cord-023585-n3lr9z3u	53	22	partially	partially	RB
cord-023585-n3lr9z3u	53	23	purified	purify	VBN
cord-023585-n3lr9z3u	53	24	human	human	NN
cord-023585-n3lr9z3u	53	25	leucocyte	leucocyte	NNP
cord-023585-n3lr9z3u	54	1	interferon	interferon	NN
cord-023585-n3lr9z3u	54	2	to	to	IN
cord-023585-n3lr9z3u	54	3	volunteers	volunteer	NNS
cord-023585-n3lr9z3u	54	4	was	be	VBD
cord-023585-n3lr9z3u	54	5	shown	show	VBN
cord-023585-n3lr9z3u	54	6	to	to	TO
cord-023585-n3lr9z3u	54	7	prevent	prevent	VB
cord-023585-n3lr9z3u	54	8	colds	cold	NNS
cord-023585-n3lr9z3u	54	9	caused	cause	VBN
cord-023585-n3lr9z3u	54	10	by	by	IN
cord-023585-n3lr9z3u	54	11	rhinovirus	rhinovirus	NN
cord-023585-n3lr9z3u	54	12	type	type	NN
cord-023585-n3lr9z3u	54	13	4	4	CD
cord-023585-n3lr9z3u	54	14	(	(	-LRB-
cord-023585-n3lr9z3u	54	15	Ref	ref	NN
cord-023585-n3lr9z3u	54	16	.	.	.
cord-023585-n3lr9z3u	54	17	5	5	LS
cord-023585-n3lr9z3u	54	18	)	)	-RRB-
cord-023585-n3lr9z3u	54	19	.	.	.
cord-023585-n3lr9z3u	55	1	Rhinoviruses	rhinovirus	NNS
cord-023585-n3lr9z3u	55	2	cause	cause	VBP
cord-023585-n3lr9z3u	55	3	approximately	approximately	RB
cord-023585-n3lr9z3u	55	4	50	50	CD
cord-023585-n3lr9z3u	55	5	%	%	NN
cord-023585-n3lr9z3u	55	6	of	of	IN
cord-023585-n3lr9z3u	55	7	colds	cold	NNS
cord-023585-n3lr9z3u	55	8	.	.	.
cord-023585-n3lr9z3u	56	1	However	however	RB
cord-023585-n3lr9z3u	56	2	,	,	,
cord-023585-n3lr9z3u	56	3	leucocytes	leucocyte	NNS
cord-023585-n3lr9z3u	56	4	from	from	IN
cord-023585-n3lr9z3u	56	5	30	30	CD
cord-023585-n3lr9z3u	56	6	-	-	SYM
cord-023585-n3lr9z3u	56	7	50	50	CD
cord-023585-n3lr9z3u	56	8	donations	donation	NNS
cord-023585-n3lr9z3u	56	9	of	of	IN
cord-023585-n3lr9z3u	56	10	blood	blood	NN
cord-023585-n3lr9z3u	56	11	were	be	VBD
cord-023585-n3lr9z3u	56	12	required	require	VBN
cord-023585-n3lr9z3u	56	13	to	to	TO
cord-023585-n3lr9z3u	56	14	produce	produce	VB
cord-023585-n3lr9z3u	56	15	the	the	DT
cord-023585-n3lr9z3u	56	16	14	14	CD
cord-023585-n3lr9z3u	56	17	MU	MU	NNS
cord-023585-n3lr9z3u	56	18	of	of	IN
cord-023585-n3lr9z3u	56	19	interferon	interferon	NN
cord-023585-n3lr9z3u	56	20	used	use	VBN
cord-023585-n3lr9z3u	56	21	to	to	TO
cord-023585-n3lr9z3u	56	22	treat	treat	VB
cord-023585-n3lr9z3u	56	23	each	each	DT
cord-023585-n3lr9z3u	56	24	volunteer	volunteer	NN
cord-023585-n3lr9z3u	56	25	.	.	.
cord-023585-n3lr9z3u	57	1	Furthermore	furthermore	RB
cord-023585-n3lr9z3u	57	2	,	,	,
cord-023585-n3lr9z3u	57	3	the	the	DT
cord-023585-n3lr9z3u	57	4	use	use	NN
cord-023585-n3lr9z3u	57	5	of	of	IN
cord-023585-n3lr9z3u	57	6	partially	partially	RB
cord-023585-n3lr9z3u	57	7	purified	purify	VBN
cord-023585-n3lr9z3u	57	8	material	material	NN
cord-023585-n3lr9z3u	57	9	in	in	IN
cord-023585-n3lr9z3u	57	10	which	which	WDT
cord-023585-n3lr9z3u	57	11	only	only	RB
cord-023585-n3lr9z3u	57	12	about	about	RB
cord-023585-n3lr9z3u	57	13	1	1	CD
cord-023585-n3lr9z3u	57	14	%	%	NN
cord-023585-n3lr9z3u	57	15	of	of	IN
cord-023585-n3lr9z3u	57	16	the	the	DT
cord-023585-n3lr9z3u	57	17	protein	protein	NN
cord-023585-n3lr9z3u	57	18	was	be	VBD
cord-023585-n3lr9z3u	57	19	interferon	interferon	NN
cord-023585-n3lr9z3u	57	20	also	also	RB
cord-023585-n3lr9z3u	57	21	raised	raise	VBD
cord-023585-n3lr9z3u	57	22	the	the	DT
cord-023585-n3lr9z3u	57	23	question	question	NN
cord-023585-n3lr9z3u	57	24	of	of	IN
cord-023585-n3lr9z3u	57	25	whether	whether	IN
cord-023585-n3lr9z3u	57	26	interferon	interferon	NN
cord-023585-n3lr9z3u	57	27	itself	-PRON-	PRP
cord-023585-n3lr9z3u	57	28	was	be	VBD
cord-023585-n3lr9z3u	57	29	responsible	responsible	JJ
cord-023585-n3lr9z3u	57	30	for	for	IN
cord-023585-n3lr9z3u	57	31	preventing	prevent	VBG
cord-023585-n3lr9z3u	57	32	rhinovirus	rhinovirus	NN
cord-023585-n3lr9z3u	57	33	infection	infection	NN
cord-023585-n3lr9z3u	57	34	.	.	.
cord-023585-n3lr9z3u	58	1	Could	Could	MD
cord-023585-n3lr9z3u	58	2	the	the	DT
cord-023585-n3lr9z3u	58	3	activity	activity	NN
cord-023585-n3lr9z3u	58	4	have	have	VBP
cord-023585-n3lr9z3u	58	5	been	be	VBN
cord-023585-n3lr9z3u	58	6	due	due	JJ
cord-023585-n3lr9z3u	58	7	to	to	IN
cord-023585-n3lr9z3u	58	8	contaminating	contaminate	VBG
cord-023585-n3lr9z3u	58	9	,	,	,
cord-023585-n3lr9z3u	58	10	biologically	biologically	RB
cord-023585-n3lr9z3u	58	11	active	active	JJ
cord-023585-n3lr9z3u	58	12	molecules	molecule	NNS
cord-023585-n3lr9z3u	58	13	also	also	RB
cord-023585-n3lr9z3u	58	14	derived	derive	VBN
cord-023585-n3lr9z3u	58	15	from	from	IN
cord-023585-n3lr9z3u	58	16	human	human	JJ
cord-023585-n3lr9z3u	58	17	leucocytes	leucocyte	NNS
cord-023585-n3lr9z3u	58	18	?	?	.
cord-023585-n3lr9z3u	59	1	This	this	DT
cord-023585-n3lr9z3u	59	2	question	question	NN
cord-023585-n3lr9z3u	59	3	was	be	VBD
cord-023585-n3lr9z3u	59	4	answered	answer	VBN
cord-023585-n3lr9z3u	59	5	in	in	IN
cord-023585-n3lr9z3u	59	6	a	a	DT
cord-023585-n3lr9z3u	59	7	further	further	JJ
cord-023585-n3lr9z3u	59	8	experiment	experiment	NN
cord-023585-n3lr9z3u	59	9	carried	carry	VBN
cord-023585-n3lr9z3u	59	10	out	out	RP
cord-023585-n3lr9z3u	59	11	in	in	IN
cord-023585-n3lr9z3u	59	12	1982	1982	CD
cord-023585-n3lr9z3u	59	13	,	,	,
cord-023585-n3lr9z3u	59	14	in	in	IN
cord-023585-n3lr9z3u	59	15	which	which	WDT
cord-023585-n3lr9z3u	59	16	HulFN	HulFN	VBZ
cord-023585-n3lr9z3u	59	17	a	a	DT
cord-023585-n3lr9z3u	59	18	,	,	,
cord-023585-n3lr9z3u	59	19	purified	purify	VBN
cord-023585-n3lr9z3u	59	20	to	to	IN
cord-023585-n3lr9z3u	59	21	virtual	virtual	JJ
cord-023585-n3lr9z3u	59	22	homogeneity	homogeneity	NN
cord-023585-n3lr9z3u	59	23	on	on	IN
cord-023585-n3lr9z3u	59	24	a	a	DT
cord-023585-n3lr9z3u	59	25	monoclonal	monoclonal	JJ
cord-023585-n3lr9z3u	59	26	antibody	antibody	NN
cord-023585-n3lr9z3u	59	27	affinity	affinity	NN
cord-023585-n3lr9z3u	59	28	column	column	NN
cord-023585-n3lr9z3u	59	29	was	be	VBD
cord-023585-n3lr9z3u	59	30	shown	show	VBN
cord-023585-n3lr9z3u	59	31	to	to	TO
cord-023585-n3lr9z3u	59	32	prevent	prevent	VB
cord-023585-n3lr9z3u	59	33	colds	cold	NNS
cord-023585-n3lr9z3u	59	34	caused	cause	VBN
cord-023585-n3lr9z3u	59	35	by	by	IN
cord-023585-n3lr9z3u	59	36	another	another	DT
cord-023585-n3lr9z3u	59	37	rhinovirus	rhinovirus	NN
cord-023585-n3lr9z3u	59	38	,	,	,
cord-023585-n3lr9z3u	59	39	type	type	NN
cord-023585-n3lr9z3u	59	40	9	9	CD
cord-023585-n3lr9z3u	59	41	(	(	-LRB-
cord-023585-n3lr9z3u	59	42	Ref	ref	NN
cord-023585-n3lr9z3u	59	43	.	.	.
cord-023585-n3lr9z3u	59	44	6	6	CD
cord-023585-n3lr9z3u	59	45	)	)	-RRB-
cord-023585-n3lr9z3u	59	46	.	.	.
cord-023585-n3lr9z3u	60	1	A	a	DT
cord-023585-n3lr9z3u	60	2	total	total	JJ
cord-023585-n3lr9z3u	60	3	dose	dose	NN
cord-023585-n3lr9z3u	60	4	of	of	IN
cord-023585-n3lr9z3u	60	5	90	90	CD
cord-023585-n3lr9z3u	60	6	MU	MU	NNP
cord-023585-n3lr9z3u	60	7	was	be	VBD
cord-023585-n3lr9z3u	60	8	given	give	VBN
cord-023585-n3lr9z3u	60	9	intranasally	intranasally	RB
cord-023585-n3lr9z3u	60	10	to	to	IN
cord-023585-n3lr9z3u	60	11	each	each	DT
cord-023585-n3lr9z3u	60	12	volunteer	volunteer	NN
cord-023585-n3lr9z3u	60	13	over	over	IN
cord-023585-n3lr9z3u	60	14	a	a	DT
cord-023585-n3lr9z3u	60	15	period	period	NN
cord-023585-n3lr9z3u	60	16	of	of	IN
cord-023585-n3lr9z3u	60	17	4	4	CD
cord-023585-n3lr9z3u	60	18	days	day	NNS
cord-023585-n3lr9z3u	60	19	(	(	-LRB-
cord-023585-n3lr9z3u	60	20	12	12	CD
cord-023585-n3lr9z3u	60	21	doses	dose	NNS
cord-023585-n3lr9z3u	60	22	,	,	,
cord-023585-n3lr9z3u	60	23	3	3	CD
cord-023585-n3lr9z3u	60	24	doses	dose	NNS
cord-023585-n3lr9z3u	60	25	daily	daily	RB
cord-023585-n3lr9z3u	60	26	)	)	-RRB-
cord-023585-n3lr9z3u	60	27	.	.	.
cord-023585-n3lr9z3u	61	1	Four	four	CD
cord-023585-n3lr9z3u	61	2	doses	dose	NNS
cord-023585-n3lr9z3u	61	3	were	be	VBD
cord-023585-n3lr9z3u	61	4	given	give	VBN
cord-023585-n3lr9z3u	61	5	before	before	RB
cord-023585-n3lr9z3u	61	6	,	,	,
cord-023585-n3lr9z3u	61	7	and	and	CC
cord-023585-n3lr9z3u	61	8	8	8	CD
cord-023585-n3lr9z3u	61	9	after	after	IN
cord-023585-n3lr9z3u	61	10	vixus	vixus	NNP
cord-023585-n3lr9z3u	61	11	challenge	challenge	NN
cord-023585-n3lr9z3u	61	12	.	.	.
cord-023585-n3lr9z3u	62	1	There	there	EX
cord-023585-n3lr9z3u	62	2	was	be	VBD
cord-023585-n3lr9z3u	62	3	a	a	DT
cord-023585-n3lr9z3u	62	4	dramatic	dramatic	JJ
cord-023585-n3lr9z3u	62	5	reduction	reduction	NN
cord-023585-n3lr9z3u	62	6	in	in	IN
cord-023585-n3lr9z3u	62	7	the	the	DT
cord-023585-n3lr9z3u	62	8	frequency	frequency	NN
cord-023585-n3lr9z3u	62	9	of	of	IN
cord-023585-n3lr9z3u	62	10	colds	cold	NNS
cord-023585-n3lr9z3u	62	11	in	in	IN
cord-023585-n3lr9z3u	62	12	the	the	DT
cord-023585-n3lr9z3u	62	13	interferon	interferon	NN
cord-023585-n3lr9z3u	62	14	treated	treat	VBN
cord-023585-n3lr9z3u	62	15	group	group	NN
cord-023585-n3lr9z3u	62	16	(	(	-LRB-
cord-023585-n3lr9z3u	62	17	Table	Table	NNP
cord-023585-n3lr9z3u	62	18	1	1	CD
cord-023585-n3lr9z3u	62	19	)	)	-RRB-
cord-023585-n3lr9z3u	62	20	.	.	.
cord-023585-n3lr9z3u	63	1	This	this	DT
cord-023585-n3lr9z3u	63	2	was	be	VBD
cord-023585-n3lr9z3u	63	3	accompanied	accompany	VBN
cord-023585-n3lr9z3u	63	4	by	by	IN
cord-023585-n3lr9z3u	63	5	lesser	less	JJR
cord-023585-n3lr9z3u	63	6	reductions	reduction	NNS
cord-023585-n3lr9z3u	63	7	in	in	IN
cord-023585-n3lr9z3u	63	8	the	the	DT
cord-023585-n3lr9z3u	63	9	number	number	NN
cord-023585-n3lr9z3u	63	10	of	of	IN
cord-023585-n3lr9z3u	63	11	volunteers	volunteer	NNS
cord-023585-n3lr9z3u	63	12	who	who	WP
cord-023585-n3lr9z3u	63	13	shed	shed	VBP
cord-023585-n3lr9z3u	63	14	virus	virus	NN
cord-023585-n3lr9z3u	63	15	,	,	,
cord-023585-n3lr9z3u	63	16	or	or	CC
cord-023585-n3lr9z3u	63	17	who	who	WP
cord-023585-n3lr9z3u	63	18	had	have	VBD
cord-023585-n3lr9z3u	63	19	an	an	DT
cord-023585-n3lr9z3u	63	20	increase	increase	NN
cord-023585-n3lr9z3u	63	21	in	in	IN
cord-023585-n3lr9z3u	63	22	serum	serum	NN
cord-023585-n3lr9z3u	63	23	neutralizing	neutralize	VBG
cord-023585-n3lr9z3u	63	24	antibody	antibody	NN
cord-023585-n3lr9z3u	63	25	to	to	IN
cord-023585-n3lr9z3u	63	26	the	the	DT
cord-023585-n3lr9z3u	63	27	challenge	challenge	NN
cord-023585-n3lr9z3u	63	28	virus	virus	NN
cord-023585-n3lr9z3u	63	29	.	.	.
cord-023585-n3lr9z3u	64	1	In	in	IN
cord-023585-n3lr9z3u	64	2	a	a	DT
cord-023585-n3lr9z3u	64	3	further	further	JJ
cord-023585-n3lr9z3u	64	4	experiment	experiment	NN
cord-023585-n3lr9z3u	64	5	conducted	conduct	VBN
cord-023585-n3lr9z3u	64	6	under	under	IN
cord-023585-n3lr9z3u	64	7	an	an	DT
cord-023585-n3lr9z3u	64	8	identical	identical	JJ
cord-023585-n3lr9z3u	64	9	protocol	protocol	NN
cord-023585-n3lr9z3u	64	10	,	,	,
cord-023585-n3lr9z3u	64	11	closely	closely	RB
cord-023585-n3lr9z3u	64	12	similar	similar	JJ
cord-023585-n3lr9z3u	64	13	results	result	NNS
cord-023585-n3lr9z3u	64	14	were	be	VBD
cord-023585-n3lr9z3u	64	15	achieved	achieve	VBN
cord-023585-n3lr9z3u	64	16	using	use	VBG
cord-023585-n3lr9z3u	64	17	highly	highly	RB
cord-023585-n3lr9z3u	64	18	purified	purify	VBN
cord-023585-n3lr9z3u	64	19	,	,	,
cord-023585-n3lr9z3u	64	20	HulFN	HulFN	NNP
cord-023585-n3lr9z3u	64	21	a-2	a-2	NN
cord-023585-n3lr9z3u	64	22	,	,	,
cord-023585-n3lr9z3u	64	23	pro	pro	JJ
cord-023585-n3lr9z3u	64	24	-	-	JJ
cord-023585-n3lr9z3u	64	25	duced	duced	JJ
cord-023585-n3lr9z3u	64	26	in	in	IN
cord-023585-n3lr9z3u	64	27	Escherichia	Escherichia	NNP
cord-023585-n3lr9z3u	64	28	coil	coil	NN
cord-023585-n3lr9z3u	64	29	7	7	CD
cord-023585-n3lr9z3u	64	30	(	(	-LRB-
cord-023585-n3lr9z3u	64	31	manufactured	manufacture	VBN
cord-023585-n3lr9z3u	64	32	by	by	IN
cord-023585-n3lr9z3u	64	33	Schering	Schering	NNP
cord-023585-n3lr9z3u	64	34	Plough	Plough	NNP
cord-023585-n3lr9z3u	64	35	)	)	-RRB-
cord-023585-n3lr9z3u	64	36	.	.	.
cord-023585-n3lr9z3u	65	1	This	this	DT
cord-023585-n3lr9z3u	65	2	experiment	experiment	NN
cord-023585-n3lr9z3u	65	3	clearly	clearly	RB
cord-023585-n3lr9z3u	65	4	demonstrated	demonstrate	VBD
cord-023585-n3lr9z3u	65	5	that	that	IN
cord-023585-n3lr9z3u	65	6	interferons	interferon	NNS
cord-023585-n3lr9z3u	65	7	produced	produce	VBN
cord-023585-n3lr9z3u	65	8	in	in	IN
cord-023585-n3lr9z3u	65	9	bacteria	bacteria	NNS
cord-023585-n3lr9z3u	65	10	by	by	IN
cord-023585-n3lr9z3u	65	11	recombinant	recombinant	JJ
cord-023585-n3lr9z3u	65	12	DNA	dna	NN
cord-023585-n3lr9z3u	65	13	techniques	technique	NNS
cord-023585-n3lr9z3u	65	14	could	could	MD
cord-023585-n3lr9z3u	65	15	be	be	VB
cord-023585-n3lr9z3u	65	16	as	as	RB
cord-023585-n3lr9z3u	65	17	active	active	JJ
cord-023585-n3lr9z3u	65	18	as	as	IN
cord-023585-n3lr9z3u	65	19	those	those	DT
cord-023585-n3lr9z3u	65	20	produced	produce	VBN
cord-023585-n3lr9z3u	65	21	by	by	IN
cord-023585-n3lr9z3u	65	22	human	human	JJ
cord-023585-n3lr9z3u	65	23	celk	celk	NN
cord-023585-n3lr9z3u	65	24	.	.	.
cord-023585-n3lr9z3u	66	1	How	how	WRB
cord-023585-n3lr9z3u	66	2	can	can	MD
cord-023585-n3lr9z3u	66	3	interferon	interferon	RB
cord-023585-n3lr9z3u	66	4	be	be	VB
cord-023585-n3lr9z3u	66	5	used	use	VBN
cord-023585-n3lr9z3u	66	6	in	in	IN
cord-023585-n3lr9z3u	66	7	prm'tke	prm'tke	NNS
cord-023585-n3lr9z3u	66	8	?	?	.
cord-023585-n3lr9z3u	67	1	In	in	IN
cord-023585-n3lr9z3u	67	2	these	these	DT
cord-023585-n3lr9z3u	67	3	experiments	experiment	NNS
cord-023585-n3lr9z3u	67	4	,	,	,
cord-023585-n3lr9z3u	67	5	interferon	interferon	NN
cord-023585-n3lr9z3u	67	6	was	be	VBD
cord-023585-n3lr9z3u	67	7	given	give	VBN
cord-023585-n3lr9z3u	67	8	intranasally	intranasally	RB
cord-023585-n3lr9z3u	67	9	in	in	IN
cord-023585-n3lr9z3u	67	10	large	large	JJ
cord-023585-n3lr9z3u	67	11	doses	dose	NNS
cord-023585-n3lr9z3u	67	12	by	by	IN
cord-023585-n3lr9z3u	67	13	a	a	DT
cord-023585-n3lr9z3u	67	14	physidan	physidan	NN
cord-023585-n3lr9z3u	67	15	.	.	.
cord-023585-n3lr9z3u	68	1	Therefore	therefore	RB
cord-023585-n3lr9z3u	68	2	ffinterferon	ffinterferon	NNP
cord-023585-n3lr9z3u	68	3	is	be	VBZ
cord-023585-n3lr9z3u	68	4	to	to	TO
cord-023585-n3lr9z3u	68	5	find	find	VB
cord-023585-n3lr9z3u	68	6	application	application	NN
cord-023585-n3lr9z3u	68	7	as	as	IN
cord-023585-n3lr9z3u	68	8	a	a	DT
cord-023585-n3lr9z3u	68	9	prophylactic	prophylactic	NN
cord-023585-n3lr9z3u	68	10	against	against	IN
cord-023585-n3lr9z3u	68	11	the	the	DT
cord-023585-n3lr9z3u	68	12	common	common	JJ
cord-023585-n3lr9z3u	68	13	cold	cold	NN
cord-023585-n3lr9z3u	68	14	.	.	.
cord-023585-n3lr9z3u	69	1	two	two	CD
cord-023585-n3lr9z3u	69	2	questions	question	NNS
cord-023585-n3lr9z3u	69	3	have	have	VBP
cord-023585-n3lr9z3u	69	4	to	to	TO
cord-023585-n3lr9z3u	69	5	be	be	VB
cord-023585-n3lr9z3u	69	6	answered	answer	VBN
cord-023585-n3lr9z3u	69	7	.	.	.
cord-023585-n3lr9z3u	70	1	Firstly	firstly	RB
cord-023585-n3lr9z3u	70	2	,	,	,
cord-023585-n3lr9z3u	70	3	could	could	MD
cord-023585-n3lr9z3u	70	4	people	people	NNS
cord-023585-n3lr9z3u	70	5	treat	treat	VB
cord-023585-n3lr9z3u	70	6	themselves	-PRON-	PRP
cord-023585-n3lr9z3u	70	7	with	with	IN
cord-023585-n3lr9z3u	70	8	interferon	interferon	NN
cord-023585-n3lr9z3u	70	9	using	use	VBG
cord-023585-n3lr9z3u	70	10	a	a	DT
cord-023585-n3lr9z3u	70	11	simple	simple	JJ
cord-023585-n3lr9z3u	70	12	design	design	NN
cord-023585-n3lr9z3u	70	13	of	of	IN
cord-023585-n3lr9z3u	70	14	nasal	nasal	NN
cord-023585-n3lr9z3u	70	15	spray	spray	NN
cord-023585-n3lr9z3u	70	16	?	?	.
cord-023585-n3lr9z3u	71	1	Sc	Sc	NNP
cord-023585-n3lr9z3u	71	2	-	-	HYPH
cord-023585-n3lr9z3u	71	3	condly	condly	NNP
cord-023585-n3lr9z3u	71	4	,	,	,
cord-023585-n3lr9z3u	71	5	what	what	WP
cord-023585-n3lr9z3u	71	6	is	be	VBZ
cord-023585-n3lr9z3u	71	7	the	the	DT
cord-023585-n3lr9z3u	71	8	minimum	minimum	JJ
cord-023585-n3lr9z3u	71	9	quantity	quantity	NN
cord-023585-n3lr9z3u	71	10	of	of	IN
cord-023585-n3lr9z3u	71	11	interferon	interferon	NN
cord-023585-n3lr9z3u	71	12	necessary	necessary	JJ
cord-023585-n3lr9z3u	71	13	to	to	TO
cord-023585-n3lr9z3u	71	14	protect	protect	VB
cord-023585-n3lr9z3u	71	15	against	against	IN
cord-023585-n3lr9z3u	71	16	infection	infection	NN
cord-023585-n3lr9z3u	71	17	with	with	IN
cord-023585-n3lr9z3u	71	18	cold	cold	JJ
cord-023585-n3lr9z3u	71	19	viruses	virus	NNS
cord-023585-n3lr9z3u	71	20	?	?	.
cord-023585-n3lr9z3u	72	1	Answers	answer	NNS
cord-023585-n3lr9z3u	72	2	to	to	IN
cord-023585-n3lr9z3u	72	3	these	these	DT
cord-023585-n3lr9z3u	72	4	questions	question	NNS
cord-023585-n3lr9z3u	72	5	were	be	VBD
cord-023585-n3lr9z3u	72	6	sought	seek	VBN
cord-023585-n3lr9z3u	72	7	in	in	IN
cord-023585-n3lr9z3u	72	8	a	a	DT
cord-023585-n3lr9z3u	72	9	dose	dose	NN
cord-023585-n3lr9z3u	72	10	-	-	HYPH
cord-023585-n3lr9z3u	72	11	ranging	range	VBG
cord-023585-n3lr9z3u	72	12	study	study	NN
cord-023585-n3lr9z3u	72	13	,	,	,
cord-023585-n3lr9z3u	72	14	in	in	IN
cord-023585-n3lr9z3u	72	15	which	which	WDT
cord-023585-n3lr9z3u	72	16	volunteers	volunteer	NNS
cord-023585-n3lr9z3u	72	17	gave	give	VBD
cord-023585-n3lr9z3u	72	18	themselves	-PRON-	PRP
cord-023585-n3lr9z3u	72	19	various	various	JJ
cord-023585-n3lr9z3u	72	20	doses	dose	NNS
cord-023585-n3lr9z3u	72	21	of	of	IN
cord-023585-n3lr9z3u	72	22	HulFN	HulFN	NNP
cord-023585-n3lr9z3u	72	23	a-2	a-2	NN
cord-023585-n3lr9z3u	72	24	using	use	VBG
cord-023585-n3lr9z3u	72	25	a	a	DT
cord-023585-n3lr9z3u	72	26	finger	finger	NN
cord-023585-n3lr9z3u	72	27	-	-	HYPH
cord-023585-n3lr9z3u	72	28	actuated	actuate	VBN
cord-023585-n3lr9z3u	72	29	nasal	nasal	NN
cord-023585-n3lr9z3u	72	30	spray	spray	NN
cord-023585-n3lr9z3u	72	31	s	s	NNP
cord-023585-n3lr9z3u	72	32	.	.	.
cord-023585-n3lr9z3u	73	1	Interferon	Interferon	NNP
cord-023585-n3lr9z3u	73	2	was	be	VBD
cord-023585-n3lr9z3u	73	3	given	give	VBN
cord-023585-n3lr9z3u	73	4	for	for	IN
cord-023585-n3lr9z3u	73	5	one	one	CD
cord-023585-n3lr9z3u	73	6	day	day	NN
cord-023585-n3lr9z3u	73	7	before	before	RB
cord-023585-n3lr9z3u	73	8	,	,	,
cord-023585-n3lr9z3u	73	9	and	and	CC
cord-023585-n3lr9z3u	73	10	3	3	CD
cord-023585-n3lr9z3u	73	11	days	day	NNS
cord-023585-n3lr9z3u	73	12	after	after	RB
cord-023585-n3lr9z3u	73	13	,	,	,
cord-023585-n3lr9z3u	73	14	challenge	challenge	VBP
cord-023585-n3lr9z3u	73	15	with	with	IN
cord-023585-n3lr9z3u	73	16	virulent	virulent	JJ
cord-023585-n3lr9z3u	73	17	human	human	JJ
cord-023585-n3lr9z3u	73	18	rhinoviruses	rhinovirus	NNS
cord-023585-n3lr9z3u	73	19	.	.	.
cord-023585-n3lr9z3u	74	1	Not	not	RB
cord-023585-n3lr9z3u	74	2	only	only	RB
cord-023585-n3lr9z3u	74	3	was	be	VBD
cord-023585-n3lr9z3u	74	4	the	the	DT
cord-023585-n3lr9z3u	74	5	dose	dose	NN
cord-023585-n3lr9z3u	74	6	of	of	IN
cord-023585-n3lr9z3u	74	7	interferon	interferon	NN
cord-023585-n3lr9z3u	74	8	varied	vary	VBN
cord-023585-n3lr9z3u	74	9	,	,	,
cord-023585-n3lr9z3u	74	10	but	but	CC
cord-023585-n3lr9z3u	74	11	also	also	RB
cord-023585-n3lr9z3u	74	12	the	the	DT
cord-023585-n3lr9z3u	74	13	time	time	NN
cord-023585-n3lr9z3u	74	14	of	of	IN
cord-023585-n3lr9z3u	74	15	virus	virus	NN
cord-023585-n3lr9z3u	74	16	challenge	challenge	NN
cord-023585-n3lr9z3u	74	17	in	in	IN
cord-023585-n3lr9z3u	74	18	relation	relation	NN
cord-023585-n3lr9z3u	74	19	to	to	IN
cord-023585-n3lr9z3u	74	20	a	a	DT
cord-023585-n3lr9z3u	74	21	dose	dose	NN
cord-023585-n3lr9z3u	74	22	,	,	,
cord-023585-n3lr9z3u	74	23	so	so	IN
cord-023585-n3lr9z3u	74	24	that	that	IN
cord-023585-n3lr9z3u	74	25	the	the	DT
cord-023585-n3lr9z3u	74	26	period	period	NN
cord-023585-n3lr9z3u	74	27	of	of	IN
cord-023585-n3lr9z3u	74	28	maximum	maximum	JJ
cord-023585-n3lr9z3u	74	29	vulnerability	vulnerability	NN
cord-023585-n3lr9z3u	74	30	to	to	IN
cord-023585-n3lr9z3u	74	31	virus	virus	NN
cord-023585-n3lr9z3u	74	32	infection	infection	NN
cord-023585-n3lr9z3u	74	33	could	could	MD
cord-023585-n3lr9z3u	74	34	be	be	VB
cord-023585-n3lr9z3u	74	35	identified	identify	VBN
cord-023585-n3lr9z3u	74	36	.	.	.
cord-023585-n3lr9z3u	75	1	The	the	DT
cord-023585-n3lr9z3u	75	2	results	result	NNS
cord-023585-n3lr9z3u	75	3	of	of	IN
cord-023585-n3lr9z3u	75	4	this	this	DT
cord-023585-n3lr9z3u	75	5	study	study	NN
cord-023585-n3lr9z3u	75	6	suggest	suggest	VBP
cord-023585-n3lr9z3u	75	7	that	that	IN
cord-023585-n3lr9z3u	75	8	at	at	RB
cord-023585-n3lr9z3u	75	9	least	least	JJS
cord-023585-n3lr9z3u	75	10	3	3	CD
cord-023585-n3lr9z3u	75	11	-	-	SYM
cord-023585-n3lr9z3u	75	12	4	4	CD
cord-023585-n3lr9z3u	75	13	MU	MU	NNS
cord-023585-n3lr9z3u	75	14	of	of	IN
cord-023585-n3lr9z3u	75	15	IFN	IFN	NNP
cord-023585-n3lr9z3u	75	16	a-2	a-2	NN
cord-023585-n3lr9z3u	75	17	self	self	NN
cord-023585-n3lr9z3u	75	18	-	-	HYPH
cord-023585-n3lr9z3u	75	19	administered	administer	VBN
cord-023585-n3lr9z3u	75	20	intranasally	intranasally	RB
cord-023585-n3lr9z3u	75	21	3	3	CD
cord-023585-n3lr9z3u	75	22	times	time	NNS
cord-023585-n3lr9z3u	75	23	daily	daily	RB
cord-023585-n3lr9z3u	75	24	are	be	VBP
cord-023585-n3lr9z3u	75	25	necessary	necessary	JJ
cord-023585-n3lr9z3u	75	26	to	to	TO
cord-023585-n3lr9z3u	75	27	protect	protect	VB
cord-023585-n3lr9z3u	75	28	against	against	IN
cord-023585-n3lr9z3u	75	29	experimental	experimental	JJ
cord-023585-n3lr9z3u	75	30	rhino	rhino	NN
cord-023585-n3lr9z3u	75	31	~	~	.
cord-023585-n3lr9z3u	75	32	rus	rus	NNP
cord-023585-n3lr9z3u	75	33	infection	infection	NN
cord-023585-n3lr9z3u	75	34	.	.	.
cord-023585-n3lr9z3u	76	1	Subsequent	subsequent	JJ
cord-023585-n3lr9z3u	76	2	experiments	experiment	NNS
cord-023585-n3lr9z3u	76	3	have	have	VBP
cord-023585-n3lr9z3u	76	4	shown	show	VBN
cord-023585-n3lr9z3u	76	5	that	that	IN
cord-023585-n3lr9z3u	76	6	3	3	CD
cord-023585-n3lr9z3u	76	7	-	-	SYM
cord-023585-n3lr9z3u	76	8	4	4	CD
cord-023585-n3lr9z3u	76	9	MU	MU	NNS
cord-023585-n3lr9z3u	76	10	of	of	IN
cord-023585-n3lr9z3u	76	11	HuiFN	HuiFN	NNP
cord-023585-n3lr9z3u	77	1	a	a	LS
cord-023585-n3lr9z3u	77	2	-	-	:
cord-023585-n3lr9z3u	77	3	A	a	NN
cord-023585-n3lr9z3u	77	4	(	(	-LRB-
cord-023585-n3lr9z3u	77	5	a	a	DT
cord-023585-n3lr9z3u	77	6	similar	similar	JJ
cord-023585-n3lr9z3u	77	7	molecule	molecule	NN
cord-023585-n3lr9z3u	77	8	to	to	IN
cord-023585-n3lr9z3u	77	9	HulFN	HulFN	NNP
cord-023585-n3lr9z3u	77	10	a-	a-	XX
cord-023585-n3lr9z3u	77	11	,	,	,
cord-023585-n3lr9z3u	77	12	produced	produce	VBN
cord-023585-n3lr9z3u	77	13	by	by	IN
cord-023585-n3lr9z3u	77	14	Roche	Roche	NNP
cord-023585-n3lr9z3u	77	15	)	)	-RRB-
cord-023585-n3lr9z3u	77	16	can	can	MD
cord-023585-n3lr9z3u	77	17	protect	protect	VB
cord-023585-n3lr9z3u	77	18	against	against	IN
cord-023585-n3lr9z3u	77	19	experimental	experimental	JJ
cord-023585-n3lr9z3u	77	20	infect	infect	NN
cord-023585-n3lr9z3u	77	21	/	/	SYM
cord-023585-n3lr9z3u	77	22	on	on	IN
cord-023585-n3lr9z3u	77	23	with	with	IN
cord-023585-n3lr9z3u	77	24	a	a	DT
cord-023585-n3lr9z3u	77	25	human	human	JJ
cord-023585-n3lr9z3u	77	26	respnratory	respnratory	JJ
cord-023585-n3lr9z3u	77	27	coronavtrus	coronavtrus	NNP
cord-023585-n3lr9z3u	77	28	(	(	-LRB-
cord-023585-n3lr9z3u	77	29	see	see	VB
cord-023585-n3lr9z3u	77	30	Fig	Fig	NNP
cord-023585-n3lr9z3u	77	31	.	.	NNP
cord-023585-n3lr9z3u	77	32	2	2	LS
cord-023585-n3lr9z3u	77	33	)	)	-RRB-
cord-023585-n3lr9z3u	77	34	"	"	''
cord-023585-n3lr9z3u	77	35	.	.	.
cord-023585-n3lr9z3u	78	1	Coronaviruses	coronaviruse	NNS
cord-023585-n3lr9z3u	78	2	are	be	VBP
cord-023585-n3lr9z3u	78	3	the	the	DT
cord-023585-n3lr9z3u	78	4	~econd	~econd	NFP
cord-023585-n3lr9z3u	78	5	most	most	RBS
cord-023585-n3lr9z3u	78	6	frequently	frequently	RB
cord-023585-n3lr9z3u	78	7	encouatered	encouatered	JJ
cord-023585-n3lr9z3u	78	8	cause	cause	NN
cord-023585-n3lr9z3u	78	9	of	of	IN
cord-023585-n3lr9z3u	78	10	a	a	DT
cord-023585-n3lr9z3u	78	11	L.oid	l.oid	NN
cord-023585-n3lr9z3u	78	12	.	.	.
cord-023585-n3lr9z3u	78	13	and	and	CC
cord-023585-n3lr9z3u	78	14	are	be	VBP
cord-023585-n3lr9z3u	78	15	responsible	responsible	JJ
cord-023585-n3lr9z3u	78	16	for	for	IN
cord-023585-n3lr9z3u	78	17	15	15	CD
cord-023585-n3lr9z3u	78	18	-	-	HYPH
cord-023585-n3lr9z3u	78	19	20e	20e	NNS
cord-023585-n3lr9z3u	78	20	/	/	SYM
cord-023585-n3lr9z3u	78	21	r	r	NN
cord-023585-n3lr9z3u	78	22	of	of	IN
cord-023585-n3lr9z3u	78	23	cases	case	NNS
cord-023585-n3lr9z3u	78	24	.	.	.
cord-023585-n3lr9z3u	79	1	However	however	RB
cord-023585-n3lr9z3u	79	2	.	.	.
cord-023585-n3lr9z3u	80	1	one	one	CD
cord-023585-n3lr9z3u	80	2	more	more	JJR
cord-023585-n3lr9z3u	80	3	requirement	requirement	NN
cord-023585-n3lr9z3u	80	4	must	must	MD
cord-023585-n3lr9z3u	80	5	be	be	VB
cord-023585-n3lr9z3u	80	6	.	.	.
cord-023585-n3lr9z3u	81	1	met	meet	VBN
cord-023585-n3lr9z3u	81	2	by	by	IN
cord-023585-n3lr9z3u	81	3	a	a	DT
cord-023585-n3lr9z3u	81	4	prophylactic	prophylactic	NN
cord-023585-n3lr9z3u	81	5	against	against	IN
cord-023585-n3lr9z3u	81	6	the	the	DT
cord-023585-n3lr9z3u	81	7	common	common	JJ
cord-023585-n3lr9z3u	81	8	cold	cold	JJ
cord-023585-n3lr9z3u	81	9	-almost	-almost	HYPH
cord-023585-n3lr9z3u	81	10	complete	complete	JJ
cord-023585-n3lr9z3u	81	11	freedom	freedom	NN
cord-023585-n3lr9z3u	81	12	from	from	IN
cord-023585-n3lr9z3u	81	13	unpleasant	unpleasant	JJ
cord-023585-n3lr9z3u	81	14	snde	snde	JJ
cord-023585-n3lr9z3u	81	15	-	-	HYPH
cord-023585-n3lr9z3u	81	16	effects	effect	NNS
cord-023585-n3lr9z3u	81	17	,	,	,
cord-023585-n3lr9z3u	81	18	it	-PRON-	PRP
cord-023585-n3lr9z3u	81	19	is	be	VBZ
cord-023585-n3lr9z3u	81	20	here	here	RB
cord-023585-n3lr9z3u	81	21	that	that	DT
cord-023585-n3lr9z3u	81	22	research	research	NN
cord-023585-n3lr9z3u	81	23	has	have	VBZ
cord-023585-n3lr9z3u	81	24	run	run	VBN
cord-023585-n3lr9z3u	81	25	into	into	IN
cord-023585-n3lr9z3u	81	26	difficulties	difficulty	NNS
cord-023585-n3lr9z3u	81	27	.	.	.
cord-023585-n3lr9z3u	82	1	Further	further	JJ
cord-023585-n3lr9z3u	82	2	studies	study	NNS
cord-023585-n3lr9z3u	82	3	have	have	VBP
cord-023585-n3lr9z3u	82	4	shown	show	VBN
cord-023585-n3lr9z3u	82	5	that	that	IN
cord-023585-n3lr9z3u	82	6	while	while	IN
cord-023585-n3lr9z3u	82	7	regimens	regimen	NNS
cord-023585-n3lr9z3u	82	8	of	of	IN
cord-023585-n3lr9z3u	82	9	IFN	IFN	NNP
cord-023585-n3lr9z3u	82	10	a	a	DT
cord-023585-n3lr9z3u	82	11	similar	similar	JJ
cord-023585-n3lr9z3u	82	12	to	to	IN
cord-023585-n3lr9z3u	82	13	that	that	DT
cord-023585-n3lr9z3u	82	14	proposed	propose	VBN
cord-023585-n3lr9z3u	82	15	seem	seem	VBP
cord-023585-n3lr9z3u	82	16	to	to	IN
cord-023585-n3lr9z3u	82	17	he	-PRON-	PRP
cord-023585-n3lr9z3u	82	18	necessa~	necessa~	NNP
cord-023585-n3lr9z3u	82	19	"	"	''
cord-023585-n3lr9z3u	82	20	for	for	IN
cord-023585-n3lr9z3u	82	21	protection	protection	NN
cord-023585-n3lr9z3u	82	22	against	against	IN
cord-023585-n3lr9z3u	82	23	natural	natural	JJ
cord-023585-n3lr9z3u	82	24	colds	cold	NNS
cord-023585-n3lr9z3u	82	25	,	,	,
cord-023585-n3lr9z3u	82	26	such	such	JJ
cord-023585-n3lr9z3u	82	27	doses	dose	NNS
cord-023585-n3lr9z3u	82	28	are	be	VBP
cord-023585-n3lr9z3u	82	29	also	also	RB
cord-023585-n3lr9z3u	82	30	toxi=	toxi=	JJ
cord-023585-n3lr9z3u	82	31	,	,	,
cord-023585-n3lr9z3u	82	32	and	and	CC
cord-023585-n3lr9z3u	82	33	produce	produce	VB
cord-023585-n3lr9z3u	82	34	a	a	DT
cord-023585-n3lr9z3u	82	35	mild	mild	JJ
cord-023585-n3lr9z3u	82	36	inflammation	inflammation	NN
cord-023585-n3lr9z3u	82	37	of	of	IN
cord-023585-n3lr9z3u	82	38	the	the	DT
cord-023585-n3lr9z3u	82	39	nasal	nasal	NN
cord-023585-n3lr9z3u	82	40	mucosa	mucosa	JJ
cord-023585-n3lr9z3u	82	41	.	.	.
cord-023585-n3lr9z3u	83	1	In	in	IN
cord-023585-n3lr9z3u	83	2	a	a	DT
cord-023585-n3lr9z3u	83	3	recent	recent	JJ
cord-023585-n3lr9z3u	83	4	stuly	stuly	NN
cord-023585-n3lr9z3u	83	5	from	from	IN
cord-023585-n3lr9z3u	83	6	the	the	DT
cord-023585-n3lr9z3u	83	7	University	University	NNP
cord-023585-n3lr9z3u	83	8	of	of	IN
cord-023585-n3lr9z3u	83	9	Virginia	Virginia	NNP
cord-023585-n3lr9z3u	83	10	,	,	,
cord-023585-n3lr9z3u	83	11	prclorge.d	prclorge.d	NNP
cord-023585-n3lr9z3u	83	12	intranasal	intranasal	NNP
cord-023585-n3lr9z3u	83	13	administration	administration	NN
cord-023585-n3lr9z3u	83	14	of	of	IN
cord-023585-n3lr9z3u	83	15	the	the	DT
cord-023585-n3lr9z3u	83	16	HulF?,~	hulf?,~	NN
cord-023585-n3lr9z3u	83	17	or-2	or-2	NNP
cord-023585-n3lr9z3u	83	18	was	be	VBD
cord-023585-n3lr9z3u	83	19	associated	associate	VBN
cord-023585-n3lr9z3u	83	20	with	with	IN
cord-023585-n3lr9z3u	83	21	muxr	muxr	NNP
cord-023585-n3lr9z3u	83	22	~	~	NNP
cord-023585-n3lr9z3u	83	23	d	d	XX
cord-023585-n3lr9z3u	83	24	irritation	irritation	NN
cord-023585-n3lr9z3u	83	25	in	in	IN
cord-023585-n3lr9z3u	83	26	23	23	CD
cord-023585-n3lr9z3u	83	27	%	%	NN
cord-023585-n3lr9z3u	83	28	ot	ot	NN
cord-023585-n3lr9z3u	84	1	recipients"L	recipients"L	NNP
cord-023585-n3lr9z3u	84	2	Histologically	Histologically	NNP
cord-023585-n3lr9z3u	84	3	,	,	,
cord-023585-n3lr9z3u	84	4	marked	mark	VBD
cord-023585-n3lr9z3u	84	5	epithelial	epithelial	JJ
cord-023585-n3lr9z3u	84	6	acute	acute	JJ
cord-023585-n3lr9z3u	84	7	t	t	NN
cord-023585-n3lr9z3u	84	8	qfiammation	qfiammation	NN
cord-023585-n3lr9z3u	84	9	with	with	IN
cord-023585-n3lr9z3u	84	10	ulceration	ulceration	NN
cord-023585-n3lr9z3u	84	11	occurr,'d	occurr,'d	NN
cord-023585-n3lr9z3u	84	12	in	in	IN
cord-023585-n3lr9z3u	84	13	19	19	CD
cord-023585-n3lr9z3u	84	14	%	%	NN
cord-023585-n3lr9z3u	84	15	,	,	,
cord-023585-n3lr9z3u	84	16	and	and	CC
cord-023585-n3lr9z3u	84	17	58	58	CD
cord-023585-n3lr9z3u	84	18	%	%	NN
cord-023585-n3lr9z3u	84	19	had	have	VBD
cord-023585-n3lr9z3u	84	20	pronounced	pronounce	VBN
cord-023585-n3lr9z3u	84	21	submucosal	submucosal	NNP
cord-023585-n3lr9z3u	84	22	l.~anphoq,/tic	l.~anphoq,/tic	NNP
cord-023585-n3lr9z3u	84	23	and	and	CC
cord-023585-n3lr9z3u	84	24	mononuclear	mononuclear	JJ
cord-023585-n3lr9z3u	85	1	cell	cell	NN
cord-023585-n3lr9z3u	85	2	~filtrates	~filtrates	NNPS
cord-023585-n3lr9z3u	85	3	.	.	.
cord-023585-n3lr9z3u	86	1	Although	although	IN
cord-023585-n3lr9z3u	86	2	these	these	DT
cord-023585-n3lr9z3u	86	3	abnormalities	abnormality	NNS
cord-023585-n3lr9z3u	86	4	re'solved	re'solve	VBD
cord-023585-n3lr9z3u	86	5	within	within	IN
cord-023585-n3lr9z3u	86	6	8	8	CD
cord-023585-n3lr9z3u	86	7	weeks	week	NNS
cord-023585-n3lr9z3u	86	8	after	after	IN
cord-023585-n3lr9z3u	86	9	stopping	stop	VBG
cord-023585-n3lr9z3u	86	10	treatment	treatment	NN
cord-023585-n3lr9z3u	86	11	,	,	,
cord-023585-n3lr9z3u	86	12	long	long	JJ
cord-023585-n3lr9z3u	86	13	-	-	HYPH
cord-023585-n3lr9z3u	86	14	term	term	NN
cord-023585-n3lr9z3u	86	15	administration	administration	NN
cord-023585-n3lr9z3u	86	16	of	of	IN
cord-023585-n3lr9z3u	86	17	IFN	IFN	NNP
cord-023585-n3lr9z3u	86	18	a	a	DT
cord-023585-n3lr9z3u	86	19	would	would	MD
cord-023585-n3lr9z3u	86	20	not	not	RB
cord-023585-n3lr9z3u	86	21	be	be	VB
cord-023585-n3lr9z3u	86	22	acceptable	acceptable	JJ
cord-023585-n3lr9z3u	86	23	.	.	.
cord-023585-n3lr9z3u	87	1	However	however	RB
cord-023585-n3lr9z3u	87	2	.	.	.
cord-023585-n3lr9z3u	88	1	there	there	EX
cord-023585-n3lr9z3u	88	2	has	have	VBZ
cord-023585-n3lr9z3u	88	3	been	be	VBN
cord-023585-n3lr9z3u	88	4	little	little	JJ
cord-023585-n3lr9z3u	88	5	sign	sign	NN
cord-023585-n3lr9z3u	88	6	of	of	IN
cord-023585-n3lr9z3u	88	7	irritation	irritation	NN
cord-023585-n3lr9z3u	88	8	of	of	IN
cord-023585-n3lr9z3u	88	9	volumeers	volumeers	NNP
cord-023585-n3lr9z3u	88	10	Wen	Wen	NNP
cord-023585-n3lr9z3u	89	1	interferon	interferon	NNP
cord-023585-n3lr9z3u	89	2	f	f	NNP
cord-023585-n3lr9z3u	89	3	~	~	NNP
cord-023585-n3lr9z3u	89	4	r	r	NN
cord-023585-n3lr9z3u	89	5	4	4	CD
cord-023585-n3lr9z3u	89	6	days	day	NNS
cord-023585-n3lr9z3u	89	7	.	.	.
cord-023585-n3lr9z3u	90	1	Therefore	therefore	RB
cord-023585-n3lr9z3u	90	2	interferon	interferon	NN
cord-023585-n3lr9z3u	90	3	prophylaxis	prophylaxis	NN
cord-023585-n3lr9z3u	90	4	could	could	MD
cord-023585-n3lr9z3u	90	5	be	be	VB
cord-023585-n3lr9z3u	90	6	used	use	VBN
cord-023585-n3lr9z3u	90	7	when	when	WRB
cord-023585-n3lr9z3u	90	8	the	the	DT
cord-023585-n3lr9z3u	90	9	time	time	NN
cord-023585-n3lr9z3u	90	10	of	of	IN
cord-023585-n3lr9z3u	90	11	exposure	exposure	NN
cord-023585-n3lr9z3u	90	12	to	to	IN
cord-023585-n3lr9z3u	90	13	virus	virus	NN
cord-023585-n3lr9z3u	90	14	(	(	-LRB-
cord-023585-n3lr9z3u	90	15	or	or	CC
cord-023585-n3lr9z3u	90	16	fear	fear	NN
cord-023585-n3lr9z3u	90	17	of	of	IN
cord-023585-n3lr9z3u	90	18	exposure	exposure	NN
cord-023585-n3lr9z3u	90	19	to	to	IN
cord-023585-n3lr9z3u	90	20	virus	virus	NN
cord-023585-n3lr9z3u	90	21	)	)	-RRB-
cord-023585-n3lr9z3u	90	22	can	can	MD
cord-023585-n3lr9z3u	90	23	be	be	VB
cord-023585-n3lr9z3u	90	24	predicted	predict	VBN
cord-023585-n3lr9z3u	90	25	.	.	.
cord-023585-n3lr9z3u	91	1	Examples	example	NNS
cord-023585-n3lr9z3u	91	2	of	of	IN
cord-023585-n3lr9z3u	91	3	this	this	DT
cord-023585-n3lr9z3u	91	4	situation	situation	NN
cord-023585-n3lr9z3u	91	5	would	would	MD
cord-023585-n3lr9z3u	91	6	be	be	VB
cord-023585-n3lr9z3u	91	7	contact	contact	NN
cord-023585-n3lr9z3u	91	8	with	with	IN
cord-023585-n3lr9z3u	91	9	a	a	DT
cord-023585-n3lr9z3u	91	10	cold	cold	JJ
cord-023585-n3lr9z3u	91	11	sufferer	sufferer	NN
cord-023585-n3lr9z3u	91	12	,	,	,
cord-023585-n3lr9z3u	91	13	or	or	CC
cord-023585-n3lr9z3u	91	14	before	before	IN
cord-023585-n3lr9z3u	91	15	an	an	DT
cord-023585-n3lr9z3u	91	16	examination	examination	NN
cord-023585-n3lr9z3u	91	17	or	or	CC
cord-023585-n3lr9z3u	91	18	some	some	DT
cord-023585-n3lr9z3u	91	19	other	other	JJ
cord-023585-n3lr9z3u	91	20	important	important	JJ
cord-023585-n3lr9z3u	91	21	event	event	NN
cord-023585-n3lr9z3u	91	22	.	.	.
cord-023585-n3lr9z3u	92	1	There	there	EX
cord-023585-n3lr9z3u	92	2	is	be	VBZ
cord-023585-n3lr9z3u	92	3	eveR	eveR	NNP
cord-023585-n3lr9z3u	92	4	'	'	POS
cord-023585-n3lr9z3u	92	5	reason	reason	NN
cord-023585-n3lr9z3u	92	6	to	to	TO
cord-023585-n3lr9z3u	92	7	believe	believe	VB
cord-023585-n3lr9z3u	92	8	that	that	IN
cord-023585-n3lr9z3u	92	9	the	the	DT
cord-023585-n3lr9z3u	92	10	problem	problem	NN
cord-023585-n3lr9z3u	92	11	of	of	IN
cord-023585-n3lr9z3u	92	12	poor	poor	JJ
cord-023585-n3lr9z3u	92	13	tolerance	tolerance	NN
cord-023585-n3lr9z3u	92	14	to	to	IN
cord-023585-n3lr9z3u	92	15	intranasal	intranasal	NN
cord-023585-n3lr9z3u	92	16	interferon	interferon	NN
cord-023585-n3lr9z3u	92	17	will	will	MD
cord-023585-n3lr9z3u	92	18	be	be	VB
cord-023585-n3lr9z3u	92	19	overcome	overcome	VBN
cord-023585-n3lr9z3u	92	20	.	.	.
cord-023585-n3lr9z3u	93	1	Only	only	RB
cord-023585-n3lr9z3u	93	2	a	a	DT
cord-023585-n3lr9z3u	93	3	very	very	RB
cord-023585-n3lr9z3u	93	4	.	.	.
cord-023585-n3lr9z3u	94	1	small	small	JJ
cord-023585-n3lr9z3u	94	2	number	number	NN
cord-023585-n3lr9z3u	94	3	of	of	IN
cord-023585-n3lr9z3u	94	4	interferons	interferon	NNS
cord-023585-n3lr9z3u	94	5	have	have	VBP
cord-023585-n3lr9z3u	94	6	been	be	VBN
cord-023585-n3lr9z3u	94	7	tested	test	VBN
cord-023585-n3lr9z3u	94	8	for	for	IN
cord-023585-n3lr9z3u	94	9	antiviral	antiviral	JJ
cord-023585-n3lr9z3u	94	10	activity	activity	NN
cord-023585-n3lr9z3u	94	11	and	and	CC
cord-023585-n3lr9z3u	94	12	toxicity	toxicity	NN
cord-023585-n3lr9z3u	94	13	in	in	IN
cord-023585-n3lr9z3u	94	14	the	the	DT
cord-023585-n3lr9z3u	94	15	nose	nose	NN
cord-023585-n3lr9z3u	94	16	,	,	,
cord-023585-n3lr9z3u	94	17	and	and	CC
cord-023585-n3lr9z3u	94	18	it	-PRON-	PRP
cord-023585-n3lr9z3u	94	19	is	be	VBZ
cord-023585-n3lr9z3u	94	20	conceivable	conceivable	JJ
cord-023585-n3lr9z3u	94	21	that	that	IN
cord-023585-n3lr9z3u	94	22	a	a	DT
cord-023585-n3lr9z3u	94	23	molecular	molecular	JJ
cord-023585-n3lr9z3u	94	24	subspecies	subspecies	NN
cord-023585-n3lr9z3u	94	25	of	of	IN
cord-023585-n3lr9z3u	94	26	HulFN	HulFN	NNP
cord-023585-n3lr9z3u	94	27	c~.	c~.	NNPS
cord-023585-n3lr9z3u	95	1	HuIFN	HuIFN	NNP
cord-023585-n3lr9z3u	95	2	t~	t~	ADD
cord-023585-n3lr9z3u	96	1	or	or	CC
cord-023585-n3lr9z3u	96	2	HulFN	HulFN	VBZ
cord-023585-n3lr9z3u	96	3	-¢	-¢	VBP
cord-023585-n3lr9z3u	96	4	,	,	,
cord-023585-n3lr9z3u	96	5	or	or	CC
cord-023585-n3lr9z3u	96	6	a	a	DT
cord-023585-n3lr9z3u	96	7	hybrid	hybrid	JJ
cord-023585-n3lr9z3u	96	8	interferon	interferon	NN
cord-023585-n3lr9z3u	96	9	molecule	molecule	NN
cord-023585-n3lr9z3u	96	10	prepared	prepare	VBN
cord-023585-n3lr9z3u	96	11	from	from	IN
cord-023585-n3lr9z3u	96	12	these	these	DT
cord-023585-n3lr9z3u	96	13	,	,	,
cord-023585-n3lr9z3u	96	14	may	may	MD
cord-023585-n3lr9z3u	96	15	have	have	VB
cord-023585-n3lr9z3u	96	16	an	an	DT
cord-023585-n3lr9z3u	96	17	improved	improve	VBN
cord-023585-n3lr9z3u	96	18	therapeutic	therapeutic	JJ
cord-023585-n3lr9z3u	96	19	ratio	ratio	NN
cord-023585-n3lr9z3u	96	20	.	.	.
cord-023585-n3lr9z3u	97	1	Interferon	interferon	NN
cord-023585-n3lr9z3u	97	2	could	could	MD
cord-023585-n3lr9z3u	97	3	then	then	RB
cord-023585-n3lr9z3u	97	4	be	be	VB
cord-023585-n3lr9z3u	97	5	taken	take	VBN
cord-023585-n3lr9z3u	97	6	for	for	IN
cord-023585-n3lr9z3u	97	7	prolonged	prolonged	JJ
cord-023585-n3lr9z3u	97	8	periods	period	NNS
cord-023585-n3lr9z3u	97	9	as	as	IN
cord-023585-n3lr9z3u	97	10	a	a	DT
cord-023585-n3lr9z3u	97	11	prophylactic	prophylactic	NN
cord-023585-n3lr9z3u	97	12	against	against	IN
cord-023585-n3lr9z3u	97	13	the	the	DT
cord-023585-n3lr9z3u	97	14	common	common	JJ
cord-023585-n3lr9z3u	97	15	cold	cold	NN
cord-023585-n3lr9z3u	97	16	by	by	IN
cord-023585-n3lr9z3u	97	17	patients	patient	NNS
cord-023585-n3lr9z3u	97	18	with	with	IN
cord-023585-n3lr9z3u	97	19	underlying	underlie	VBG
cord-023585-n3lr9z3u	97	20	chronic	chronic	JJ
cord-023585-n3lr9z3u	97	21	respiratory	respiratory	JJ
cord-023585-n3lr9z3u	97	22	disease	disease	NN
cord-023585-n3lr9z3u	97	23	,	,	,
cord-023585-n3lr9z3u	97	24	such	such	JJ
cord-023585-n3lr9z3u	97	25	as	as	IN
cord-023585-n3lr9z3u	97	26	bronchitis	bronchitis	NN
cord-023585-n3lr9z3u	97	27	or	or	CC
cord-023585-n3lr9z3u	97	28	asthma	asthma	NN
cord-023585-n3lr9z3u	97	29	.	.	.
cord-023585-n3lr9z3u	98	1	Not	not	RB
cord-023585-n3lr9z3u	98	2	surprisingly	surprisingly	RB
cord-023585-n3lr9z3u	98	3	therefore	therefore	RB
cord-023585-n3lr9z3u	98	4	,	,	,
cord-023585-n3lr9z3u	98	5	the	the	DT
cord-023585-n3lr9z3u	98	6	discovery	discovery	NN
cord-023585-n3lr9z3u	98	7	of	of	IN
cord-023585-n3lr9z3u	98	8	inteffemns	inteffemn	NNS
cord-023585-n3lr9z3u	98	9	with	with	IN
cord-023585-n3lr9z3u	98	10	this	this	DT
cord-023585-n3lr9z3u	98	11	desirable	desirable	JJ
cord-023585-n3lr9z3u	98	12	property	property	NN
cord-023585-n3lr9z3u	98	13	is	be	VBZ
cord-023585-n3lr9z3u	98	14	one	one	CD
cord-023585-n3lr9z3u	98	15	of	of	IN
cord-023585-n3lr9z3u	98	16	the	the	DT
cord-023585-n3lr9z3u	98	17	major	major	JJ
cord-023585-n3lr9z3u	98	18	goals	goal	NNS
cord-023585-n3lr9z3u	98	19	in	in	IN
cord-023585-n3lr9z3u	98	20	common	common	JJ
cord-023585-n3lr9z3u	98	21	cold	cold	JJ
cord-023585-n3lr9z3u	98	22	research	research	NN
cord-023585-n3lr9z3u	98	23	today	today	NN
cord-023585-n3lr9z3u	98	24	.	.	.
cord-023585-n3lr9z3u	99	1	The	the	DT
cord-023585-n3lr9z3u	99	2	question	question	NN
cord-023585-n3lr9z3u	99	3	of	of	IN
cord-023585-n3lr9z3u	99	4	whether	whether	IN
cord-023585-n3lr9z3u	99	5	interferon	interferon	NN
cord-023585-n3lr9z3u	99	6	can	can	MD
cord-023585-n3lr9z3u	99	7	be	be	VB
cord-023585-n3lr9z3u	99	8	used	use	VBN
cord-023585-n3lr9z3u	99	9	to	to	TO
cord-023585-n3lr9z3u	99	10	treat	treat	VB
cord-023585-n3lr9z3u	99	11	a	a	DT
cord-023585-n3lr9z3u	99	12	cold	cold	NN
cord-023585-n3lr9z3u	99	13	also	also	RB
cord-023585-n3lr9z3u	99	14	remains	remain	VBZ
cord-023585-n3lr9z3u	99	15	open	open	JJ
cord-023585-n3lr9z3u	99	16	.	.	.
cord-023585-n3lr9z3u	100	1	The	the	DT
cord-023585-n3lr9z3u	100	2	relatively	relatively	RB
cord-023585-n3lr9z3u	100	3	short	short	JJ
cord-023585-n3lr9z3u	100	4	course	course	NN
cord-023585-n3lr9z3u	100	5	of	of	IN
cord-023585-n3lr9z3u	100	6	the	the	DT
cord-023585-n3lr9z3u	100	7	illness	illness	NN
cord-023585-n3lr9z3u	100	8	suggests	suggest	VBZ
cord-023585-n3lr9z3u	100	9	that	that	IN
cord-023585-n3lr9z3u	100	10	virus	virus	NN
cord-023585-n3lr9z3u	100	11	replication	replication	NN
cord-023585-n3lr9z3u	100	12	in	in	IN
cord-023585-n3lr9z3u	100	13	the	the	DT
cord-023585-n3lr9z3u	100	14	nose	nose	NN
cord-023585-n3lr9z3u	100	15	oomns	oomn	NNS
cord-023585-n3lr9z3u	100	16	rapidly	rapidly	RB
cord-023585-n3lr9z3u	100	17	,	,	,
cord-023585-n3lr9z3u	100	18	and	and	CC
cord-023585-n3lr9z3u	100	19	may	may	MD
cord-023585-n3lr9z3u	100	20	even	even	RB
cord-023585-n3lr9z3u	100	21	be	be	VB
cord-023585-n3lr9z3u	100	22	essentially	essentially	RB
cord-023585-n3lr9z3u	100	23	complete	complete	JJ
cord-023585-n3lr9z3u	100	24	by	by	IN
cord-023585-n3lr9z3u	100	25	the	the	DT
cord-023585-n3lr9z3u	100	26	time	time	NN
cord-023585-n3lr9z3u	100	27	symptoms	symptom	NNS
cord-023585-n3lr9z3u	100	28	have	have	VBP
cord-023585-n3lr9z3u	100	29	begun	begin	VBN
cord-023585-n3lr9z3u	100	30	.	.	.
cord-023585-n3lr9z3u	101	1	However	however	RB
cord-023585-n3lr9z3u	101	2	,	,	,
cord-023585-n3lr9z3u	101	3	this	this	DT
cord-023585-n3lr9z3u	101	4	pessimistic	pessimistic	JJ
cord-023585-n3lr9z3u	101	5	view	view	NN
cord-023585-n3lr9z3u	101	6	has	have	VBZ
cord-023585-n3lr9z3u	101	7	yet	yet	RB
cord-023585-n3lr9z3u	101	8	to	to	TO
cord-023585-n3lr9z3u	101	9	be	be	VB
cord-023585-n3lr9z3u	101	10	confirmed	confirm	VBN
cord-023585-n3lr9z3u	101	11	,	,	,
cord-023585-n3lr9z3u	101	12	and	and	CC
cord-023585-n3lr9z3u	101	13	there	there	EX
cord-023585-n3lr9z3u	101	14	is	be	VBZ
cord-023585-n3lr9z3u	101	15	some	some	DT
cord-023585-n3lr9z3u	101	16	evidence	evidence	NN
cord-023585-n3lr9z3u	101	17	to	to	TO
cord-023585-n3lr9z3u	101	18	suggest	suggest	VB
cord-023585-n3lr9z3u	101	19	that	that	IN
cord-023585-n3lr9z3u	101	20	even	even	RB
cord-023585-n3lr9z3u	101	21	a	a	DT
cord-023585-n3lr9z3u	101	22	relatively	relatively	RB
cord-023585-n3lr9z3u	101	23	we	-PRON-	PRP
cord-023585-n3lr9z3u	101	24	~	~	CD
cord-023585-n3lr9z3u	101	25	k	k	XX
cord-023585-n3lr9z3u	101	26	antiviral	antiviral	JJ
cord-023585-n3lr9z3u	101	27	agent	agent	NN
cord-023585-n3lr9z3u	101	28	,	,	,
cord-023585-n3lr9z3u	101	29	such	such	JJ
cord-023585-n3lr9z3u	101	30	as	as	IN
cord-023585-n3lr9z3u	101	31	Enviroxime	Enviroxime	NNP
cord-023585-n3lr9z3u	101	32	(	(	-LRB-
cord-023585-n3lr9z3u	101	33	registered	register	VBN
cord-023585-n3lr9z3u	101	34	trade	trade	NN
cord-023585-n3lr9z3u	101	35	name	name	NN
cord-023585-n3lr9z3u	101	36	,	,	,
cord-023585-n3lr9z3u	101	37	produced	produce	VBN
cord-023585-n3lr9z3u	101	38	by	by	IN
cord-023585-n3lr9z3u	101	39	Eli	Eli	NNP
cord-023585-n3lr9z3u	101	40	Lilly	Lilly	NNP
cord-023585-n3lr9z3u	101	41	and	and	CC
cord-023585-n3lr9z3u	101	42	Company	Company	NNP
cord-023585-n3lr9z3u	101	43	)	)	-RRB-
cord-023585-n3lr9z3u	101	44	,	,	,
cord-023585-n3lr9z3u	101	45	administered	administer	VBN
cord-023585-n3lr9z3u	101	46	locally	locally	RB
cord-023585-n3lr9z3u	101	47	after	after	IN
cord-023585-n3lr9z3u	101	48	virus	virus	NN
cord-023585-n3lr9z3u	101	49	infection	infection	NN
cord-023585-n3lr9z3u	101	50	can	can	MD
cord-023585-n3lr9z3u	101	51	affect	affect	VB
cord-023585-n3lr9z3u	101	52	the	the	DT
cord-023585-n3lr9z3u	101	53	course	course	NN
cord-023585-n3lr9z3u	101	54	of	of	IN
cord-023585-n3lr9z3u	101	55	a	a	DT
cord-023585-n3lr9z3u	101	56	cold	cold	JJ
cord-023585-n3lr9z3u	101	57	tt	tt	NN
cord-023585-n3lr9z3u	101	58	.	.	.
cord-023585-n3lr9z3u	102	1	Perhaps	perhaps	RB
cord-023585-n3lr9z3u	102	2	a	a	DT
cord-023585-n3lr9z3u	102	3	suitable	suitable	JJ
cord-023585-n3lr9z3u	102	4	preparation	preparation	NN
cord-023585-n3lr9z3u	102	5	of	of	IN
cord-023585-n3lr9z3u	102	6	interferon	interferon	NN
cord-023585-n3lr9z3u	102	7	,	,	,
cord-023585-n3lr9z3u	102	8	which	which	WDT
cord-023585-n3lr9z3u	102	9	could	could	MD
cord-023585-n3lr9z3u	102	10	be	be	VB
cord-023585-n3lr9z3u	102	11	over	over	IN
cord-023585-n3lr9z3u	102	12	1	1	CD
cord-023585-n3lr9z3u	102	13	000	000	CD
cord-023585-n3lr9z3u	102	14	times	time	NNS
cord-023585-n3lr9z3u	102	15	more	more	RBR
cord-023585-n3lr9z3u	102	16	potent	potent	JJ
cord-023585-n3lr9z3u	102	17	than	than	IN
cord-023585-n3lr9z3u	102	18	Enviroxime	Enviroxime	NNP
cord-023585-n3lr9z3u	102	19	in	in	IN
cord-023585-n3lr9z3u	102	20	vitro	vitro	FW
cord-023585-n3lr9z3u	102	21	,	,	,
cord-023585-n3lr9z3u	102	22	could	could	MD
cord-023585-n3lr9z3u	102	23	prove	prove	VB
cord-023585-n3lr9z3u	102	24	clinically	clinically	RB
cord-023585-n3lr9z3u	102	25	useful	useful	JJ
cord-023585-n3lr9z3u	102	26	.	.	.
cord-023585-n3lr9z3u	103	1	as	as	IN
cord-023585-n3lr9z3u	103	2	modulators	modulator	NNS
cord-023585-n3lr9z3u	103	3	of	of	IN
cord-023585-n3lr9z3u	103	4	appetite	appetite	NN
cord-023585-n3lr9z3u	103	5	.	.	.
cord-023585-n3lr9z3u	104	1	The	the	DT
cord-023585-n3lr9z3u	104	2	intiuen	intiuen	NNP
cord-023585-n3lr9z3u	104	3	~	~	.
cord-023585-n3lr9z3u	104	4	es	es	XX
cord-023585-n3lr9z3u	104	5	of	of	IN
cord-023585-n3lr9z3u	104	6	other	other	JJ
cord-023585-n3lr9z3u	104	7	neurotransmitters	neurotransmitter	NNS
cord-023585-n3lr9z3u	104	8	and	and	CC
cord-023585-n3lr9z3u	104	9	the	the	DT
cord-023585-n3lr9z3u	104	10	physicochemical	physicochemical	JJ
cord-023585-n3lr9z3u	104	11	properties	property	NNS
cord-023585-n3lr9z3u	104	12	of	of	IN
cord-023585-n3lr9z3u	104	13	food	food	NN
cord-023585-n3lr9z3u	104	14	will	will	MD
cord-023585-n3lr9z3u	104	15	,	,	,
cord-023585-n3lr9z3u	104	16	therefore	therefore	RB
cord-023585-n3lr9z3u	104	17	,	,	,
cord-023585-n3lr9z3u	104	18	receive	receive	VB
cord-023585-n3lr9z3u	104	19	less	less	JJR
cord-023585-n3lr9z3u	104	20	prominence	prominence	NN
cord-023585-n3lr9z3u	104	21	.	.	.
cord-023585-n3lr9z3u	105	1	At	at	IN
cord-023585-n3lr9z3u	105	2	the	the	DT
cord-023585-n3lr9z3u	105	3	outset	outset	NN
cord-023585-n3lr9z3u	105	4	it	-PRON-	PRP
cord-023585-n3lr9z3u	105	5	should	should	MD
cord-023585-n3lr9z3u	105	6	be	be	VB
cord-023585-n3lr9z3u	105	7	stres~	stres~	NNP
cord-023585-n3lr9z3u	106	1	d	d	XX
cord-023585-n3lr9z3u	106	2	that	that	IN
cord-023585-n3lr9z3u	106	3	the	the	DT
cord-023585-n3lr9z3u	106	4	complexities	complexity	NNS
cord-023585-n3lr9z3u	106	5	of	of	IN
cord-023585-n3lr9z3u	106	6	appetite	appetite	NN
cord-023585-n3lr9z3u	106	7	regulation	regulation	NN
cord-023585-n3lr9z3u	106	8	make	make	VBP
cord-023585-n3lr9z3u	106	9	it	-PRON-	PRP
cord-023585-n3lr9z3u	106	10	extremely	extremely	RB
cord-023585-n3lr9z3u	106	11	unlikely	unlikely	JJ
cord-023585-n3lr9z3u	106	12	that	that	IN
cord-023585-n3lr9z3u	106	13	any	any	DT
cord-023585-n3lr9z3u	106	14	single	single	JJ
cord-023585-n3lr9z3u	106	15	agent	agent	NN
cord-023585-n3lr9z3u	106	16	will	will	MD
cord-023585-n3lr9z3u	106	17	prove	prove	VB
cord-023585-n3lr9z3u	106	18	to	to	TO
cord-023585-n3lr9z3u	106	19	be	be	VB
cord-023585-n3lr9z3u	106	20	the	the	DT
cord-023585-n3lr9z3u	106	21	Holy	Holy	NNP
cord-023585-n3lr9z3u	106	22	Grail	Grail	NNP
cord-023585-n3lr9z3u	106	23	of	of	IN
cord-023585-n3lr9z3u	106	24	appetite	appetite	NN
cord-023585-n3lr9z3u	106	25	suppressants	suppressant	NNS
cord-023585-n3lr9z3u	106	26	.	.	.
cord-023585-n3lr9z3u	107	1	Future	future	JJ
cord-023585-n3lr9z3u	107	2	pharmacological	pharmacological	JJ
cord-023585-n3lr9z3u	107	3	approaches	approach	NNS
cord-023585-n3lr9z3u	107	4	will	will	MD
cord-023585-n3lr9z3u	107	5	need	need	VB
cord-023585-n3lr9z3u	107	6	to	to	TO
cord-023585-n3lr9z3u	107	7	take	take	VB
cord-023585-n3lr9z3u	107	8	cognizance	cognizance	NN
cord-023585-n3lr9z3u	107	9	of	of	IN
cord-023585-n3lr9z3u	107	10	this	this	DT
cord-023585-n3lr9z3u	107	11	fact	fact	NN
cord-023585-n3lr9z3u	107	12	and	and	CC
cord-023585-n3lr9z3u	107	13	attempt	attempt	NN
cord-023585-n3lr9z3u	107	14	to	to	TO
cord-023585-n3lr9z3u	107	15	tailor	tailor	VB
cord-023585-n3lr9z3u	107	16	the	the	DT
cord-023585-n3lr9z3u	107	17	treatment	treatment	NN
cord-023585-n3lr9z3u	107	18	to	to	IN
cord-023585-n3lr9z3u	107	19	the	the	DT
cord-023585-n3lr9z3u	107	20	individual	individual	NN
cord-023585-n3lr9z3u	107	21	rather	rather	RB
cord-023585-n3lr9z3u	107	22	than	than	IN
cord-023585-n3lr9z3u	107	23	the	the	DT
cord-023585-n3lr9z3u	107	24	individual	individual	NN
cord-023585-n3lr9z3u	107	25	to	to	IN
cord-023585-n3lr9z3u	107	26	the	the	DT
cord-023585-n3lr9z3u	107	27	treatment	treatment	NN
cord-023585-n3lr9z3u	107	28	.	.	.
cord-023585-n3lr9z3u	108	1	This	this	DT
cord-023585-n3lr9z3u	108	2	is	be	VBZ
cord-023585-n3lr9z3u	108	3	particularly	particularly	RB
cord-023585-n3lr9z3u	108	4	important	important	JJ
cord-023585-n3lr9z3u	108	5	in	in	IN
cord-023585-n3lr9z3u	108	6	view	view	NN
cord-023585-n3lr9z3u	108	7	of	of	IN
cord-023585-n3lr9z3u	108	8	the	the	DT
cord-023585-n3lr9z3u	108	9	fact	fact	NN
cord-023585-n3lr9z3u	108	10	that	that	IN
cord-023585-n3lr9z3u	108	11	the	the	DT
cord-023585-n3lr9z3u	108	12	majority	majority	NN
cord-023585-n3lr9z3u	108	13	of	of	IN
cord-023585-n3lr9z3u	108	14	peptides	peptide	NNS
cord-023585-n3lr9z3u	108	15	appear	appear	VBP
cord-023585-n3lr9z3u	108	16	to	to	TO
cord-023585-n3lr9z3u	108	17	have	have	VB
cord-023585-n3lr9z3u	108	18	multiple	multiple	JJ
cord-023585-n3lr9z3u	108	19	effects	effect	NNS
cord-023585-n3lr9z3u	108	20	,	,	,
cord-023585-n3lr9z3u	108	21	making	make	VBG
cord-023585-n3lr9z3u	108	22	it	-PRON-	PRP
cord-023585-n3lr9z3u	108	23	likely	likely	JJ
cord-023585-n3lr9z3u	108	24	that	that	IN
cord-023585-n3lr9z3u	108	25	the	the	DT
cord-023585-n3lr9z3u	108	26	indiscriminate	indiscriminate	JJ
cord-023585-n3lr9z3u	108	27	use	use	NN
cord-023585-n3lr9z3u	108	28	of	of	IN
cord-023585-n3lr9z3u	108	29	these	these	DT
cord-023585-n3lr9z3u	108	30	agents	agent	NNS
cord-023585-n3lr9z3u	108	31	,	,	,
cord-023585-n3lr9z3u	108	32	in	in	IN
cord-023585-n3lr9z3u	108	33	subjects	subject	NNS
cord-023585-n3lr9z3u	108	34	in	in	IN
cord-023585-n3lr9z3u	108	35	whom	whom	WP
cord-023585-n3lr9z3u	108	36	a	a	DT
cord-023585-n3lr9z3u	108	37	deficit	deficit	NN
cord-023585-n3lr9z3u	108	38	or	or	CC
cord-023585-n3lr9z3u	108	39	an	an	DT
cord-023585-n3lr9z3u	108	40	excess	excess	NN
cord-023585-n3lr9z3u	108	41	has	have	VBZ
cord-023585-n3lr9z3u	108	42	not	not	RB
cord-023585-n3lr9z3u	108	43	been	be	VBN
cord-023585-n3lr9z3u	108	44	demonstrated	demonstrate	VBN
cord-023585-n3lr9z3u	108	45	,	,	,
cord-023585-n3lr9z3u	108	46	will	will	MD
cord-023585-n3lr9z3u	108	47	lead	lead	VB
cord-023585-n3lr9z3u	108	48	to	to	IN
cord-023585-n3lr9z3u	108	49	an	an	DT
cord-023585-n3lr9z3u	108	50	unacceptably	unacceptably	RB
cord-023585-n3lr9z3u	108	51	high	high	JJ
cord-023585-n3lr9z3u	108	52	incidence	incidence	NN
cord-023585-n3lr9z3u	108	53	of	of	IN
cord-023585-n3lr9z3u	108	54	side	side	NN
cord-023585-n3lr9z3u	108	55	effects	effect	NNS
cord-023585-n3lr9z3u	108	56	.	.	.
cord-023585-n3lr9z3u	109	1	opuad	opuad	NNP
cord-023585-n3lr9z3u	109	2	reading	read	VBG
cord-023585-n3lr9z3u	109	3	m	m	NNP
cord-023585-n3lr9z3u	109	4	A	a	DT
cord-023585-n3lr9z3u	109	5	large	large	JJ
cord-023585-n3lr9z3u	109	6	body	body	NN
cord-023585-n3lr9z3u	109	7	of	of	IN
cord-023585-n3lr9z3u	109	8	evidence	evidence	NN
cord-023585-n3lr9z3u	109	9	has	have	VBZ
cord-023585-n3lr9z3u	109	10	now	now	RB
cord-023585-n3lr9z3u	109	11	accumulated	accumulate	VBN
cord-023585-n3lr9z3u	109	12	supporting	support	VBG
cord-023585-n3lr9z3u	109	13	a	a	DT
cord-023585-n3lr9z3u	109	14	role	role	NN
cord-023585-n3lr9z3u	109	15	for	for	IN
cord-023585-n3lr9z3u	109	16	opioid	opioid	JJ
cord-023585-n3lr9z3u	109	17	peptides	peptide	NNS
cord-023585-n3lr9z3u	109	18	in	in	IN
cord-023585-n3lr9z3u	109	19	the	the	DT
cord-023585-n3lr9z3u	109	20	modulation	modulation	NN
cord-023585-n3lr9z3u	109	21	of	of	IN
cord-023585-n3lr9z3u	109	22	feeding	feed	VBG
cord-023585-n3lr9z3u	109	23	behavior	behavior	NN
cord-023585-n3lr9z3u	109	24	t.	t.	NNP
cord-023585-n3lr9z3u	110	1	In	in	IN
cord-023585-n3lr9z3u	110	2	particular	particular	JJ
cord-023585-n3lr9z3u	110	3	,	,	,
cord-023585-n3lr9z3u	110	4	the	the	DT
cord-023585-n3lr9z3u	110	5	relatively	relatively	RB
cord-023585-n3lr9z3u	110	6	specific	specific	JJ
cord-023585-n3lr9z3u	110	7	opioid	opioid	JJ
cord-023585-n3lr9z3u	110	8	antagonist	antagonist	NN
cord-023585-n3lr9z3u	110	9	,	,	,
cord-023585-n3lr9z3u	110	10	naloxone	naloxone	NN
cord-023585-n3lr9z3u	110	11	,	,	,
cord-023585-n3lr9z3u	110	12	has	have	VBZ
cord-023585-n3lr9z3u	110	13	been	be	VBN
cord-023585-n3lr9z3u	110	14	demonstrated	demonstrate	VBN
cord-023585-n3lr9z3u	110	15	to	to	TO
cord-023585-n3lr9z3u	110	16	decrease	decrease	VB
cord-023585-n3lr9z3u	110	17	fe	fe	NNP
cord-023585-n3lr9z3u	110	18	~	~	NFP
cord-023585-n3lr9z3u	110	19	ding	ding	NNS
cord-023585-n3lr9z3u	110	20	under	under	IN
cord-023585-n3lr9z3u	110	21	a	a	DT
cord-023585-n3lr9z3u	110	22	variety	variety	NN
cord-023585-n3lr9z3u	110	23	of	of	IN
cord-023585-n3lr9z3u	110	24	conditions	condition	NNS
cord-023585-n3lr9z3u	110	25	in	in	IN
cord-023585-n3lr9z3u	110	26	many	many	JJ
cord-023585-n3lr9z3u	110	27	species	specie	NNS
cord-023585-n3lr9z3u	110	28	including	include	VBG
cord-023585-n3lr9z3u	110	29	humans	human	NNS
cord-023585-n3lr9z3u	110	30	.	.	.
cord-023585-n3lr9z3u	111	1	In	in	IN
cord-023585-n3lr9z3u	111	2	humans	human	NNS
cord-023585-n3lr9z3u	111	3	,	,	,
cord-023585-n3lr9z3u	111	4	however	however	RB
cord-023585-n3lr9z3u	111	5	,	,	,
cord-023585-n3lr9z3u	111	6	the	the	DT
cord-023585-n3lr9z3u	111	7	major	major	JJ
cord-023585-n3lr9z3u	111	8	effect	effect	NN
cord-023585-n3lr9z3u	111	9	o	o	NN
cord-023585-n3lr9z3u	111	10	!	!	.
cord-023585-n3lr9z3u	112	1	opioid	opioid	JJ
cord-023585-n3lr9z3u	112	2	blockade	blockade	NN
cord-023585-n3lr9z3u	112	3	with	with	IN
cord-023585-n3lr9z3u	112	4	naloxone	naloxone	NN
cord-023585-n3lr9z3u	112	5	appears	appear	VBZ
cord-023585-n3lr9z3u	112	6	to	to	TO
cord-023585-n3lr9z3u	112	7	be	be	VB
cord-023585-n3lr9z3u	112	8	to	to	TO
cord-023585-n3lr9z3u	112	9	reduce	reduce	VB
cord-023585-n3lr9z3u	112	10	carbohydrate	carbohydrate	NN
cord-023585-n3lr9z3u	112	11	intake	intake	NN
cord-023585-n3lr9z3u	112	12	rather	rather	RB
cord-023585-n3lr9z3u	112	13	than	than	IN
cord-023585-n3lr9z3u	112	14	to	to	TO
cord-023585-n3lr9z3u	112	15	produce	produce	VB
cord-023585-n3lr9z3u	112	16	an	an	DT
cord-023585-n3lr9z3u	112	17	absolute	absolute	JJ
cord-023585-n3lr9z3u	112	18	reduction	reduction	NN
cord-023585-n3lr9z3u	112	19	in	in	IN
cord-023585-n3lr9z3u	112	20	calories	calorie	NNS
cord-023585-n3lr9z3u	112	21	.	.	.
cord-023585-n3lr9z3u	113	1	This	this	DT
cord-023585-n3lr9z3u	113	2	reduction	reduction	NN
cord-023585-n3lr9z3u	113	3	is	be	VBZ
cord-023585-n3lr9z3u	113	4	offset	offset	VBN
cord-023585-n3lr9z3u	113	5	by	by	IN
cord-023585-n3lr9z3u	113	6	an	an	DT
cord-023585-n3lr9z3u	113	7	increase	increase	NN
cord-023585-n3lr9z3u	113	8	in	in	IN
cord-023585-n3lr9z3u	113	9	fat	fat	NN
cord-023585-n3lr9z3u	113	10	intake	intake	NN
cord-023585-n3lr9z3u	113	11	.	.	.
cord-023585-n3lr9z3u	114	1	In	in	IN
cord-023585-n3lr9z3u	114	2	addition	addition	NN
cord-023585-n3lr9z3u	114	3	,	,	,
cord-023585-n3lr9z3u	114	4	the	the	DT
cord-023585-n3lr9z3u	114	5	first	first	JJ
cord-023585-n3lr9z3u	114	6	ion	ion	NN
cord-023585-n3lr9z3u	114	7	8	8	CD
cord-023585-n3lr9z3u	114	8	term	term	NN
cord-023585-n3lr9z3u	114	9	study	study	NN
cord-023585-n3lr9z3u	114	10	in	in	IN
cord-023585-n3lr9z3u	114	11	humans	human	NNS
cord-023585-n3lr9z3u	114	12	by	by	IN
cord-023585-n3lr9z3u	114	13	Atkinson	Atkinson	NNP
cord-023585-n3lr9z3u	114	14	2	2	CD
cord-023585-n3lr9z3u	114	15	using	use	VBG
cord-023585-n3lr9z3u	114	16	the	the	DT
cord-023585-n3lr9z3u	114	17	long	long	RB
cord-023585-n3lr9z3u	114	18	-	-	HYPH
cord-023585-n3lr9z3u	114	19	acting	act	VBG
cord-023585-n3lr9z3u	114	20	opiate	opiate	NN
cord-023585-n3lr9z3u	114	21	antagonist	antagonist	NN
cord-023585-n3lr9z3u	114	22	,	,	,
cord-023585-n3lr9z3u	114	23	naltrexone	naltrexone	NN
cord-023585-n3lr9z3u	114	24	,	,	,
cord-023585-n3lr9z3u	114	25	produced	produce	VBN
cord-023585-n3lr9z3u	114	26	disap-	disap-	NNP
cord-023585-n3lr9z3u	114	27	09S2	09s2	CD
cord-023585-n3lr9z3u	114	28	)	)	-RRB-
cord-023585-n3lr9z3u	115	1	erin	erin	NNP
cord-023585-n3lr9z3u	115	2	.	.	.
cord-023585-n3lr9z3u	116	1	ciples	ciples	NNP
cord-023585-n3lr9z3u	116	2	of	of	IN
cord-023585-n3lr9z3u	116	3	gme	gme	NNP
cord-023585-n3lr9z3u	116	4	nmnipulatwn	nmnipulatwn	NNP