id	sid	tid	token	lemma	pos
cord-003130-p2h8p5bm	1	1	key	key	JJ
cord-003130-p2h8p5bm	2	1	:	:	:
cord-003130-p2h8p5bm	2	2	cord-003130-p2h8p5bm	cord-003130-p2h8p5bm	NN
cord-003130-p2h8p5bm	2	3	authors	author	NNS
cord-003130-p2h8p5bm	2	4	:	:	:
cord-003130-p2h8p5bm	2	5	Lindqvist	Lindqvist	NNP
cord-003130-p2h8p5bm	2	6	,	,	,
cord-003130-p2h8p5bm	2	7	Richard	Richard	NNP
cord-003130-p2h8p5bm	2	8	;	;	:
cord-003130-p2h8p5bm	2	9	Upadhyay	Upadhyay	NNP
cord-003130-p2h8p5bm	2	10	,	,	,
cord-003130-p2h8p5bm	2	11	Arunkumar	Arunkumar	NNP
cord-003130-p2h8p5bm	2	12	;	;	:
cord-003130-p2h8p5bm	2	13	Överby	Överby	NNP
cord-003130-p2h8p5bm	2	14	,	,	,
cord-003130-p2h8p5bm	2	15	Anna	Anna	NNP
cord-003130-p2h8p5bm	2	16	K.	K.	NNP
cord-003130-p2h8p5bm	3	1	title	title	NN
cord-003130-p2h8p5bm	3	2	:	:	:
cord-003130-p2h8p5bm	4	1	Tick	tick	VB
cord-003130-p2h8p5bm	4	2	-	-	HYPH
cord-003130-p2h8p5bm	4	3	Borne	Borne	NNP
cord-003130-p2h8p5bm	4	4	Flaviviruses	Flaviviruses	NNPS
cord-003130-p2h8p5bm	4	5	and	and	CC
cord-003130-p2h8p5bm	4	6	the	the	DT
cord-003130-p2h8p5bm	4	7	Type	type	NN
cord-003130-p2h8p5bm	4	8	I	-PRON-	PRP
cord-003130-p2h8p5bm	5	1	Interferon	Interferon	NNP
cord-003130-p2h8p5bm	5	2	Response	response	NN
cord-003130-p2h8p5bm	5	3	date	date	NN
cord-003130-p2h8p5bm	5	4	:	:	:
cord-003130-p2h8p5bm	5	5	2018	2018	CD
cord-003130-p2h8p5bm	5	6	-	-	HYPH
cord-003130-p2h8p5bm	5	7	06	06	CD
cord-003130-p2h8p5bm	5	8	-	-	SYM
cord-003130-p2h8p5bm	5	9	21	21	CD
cord-003130-p2h8p5bm	5	10	journal	journal	NN
cord-003130-p2h8p5bm	5	11	:	:	:
cord-003130-p2h8p5bm	6	1	Viruses	virus	NNS
cord-003130-p2h8p5bm	6	2	DOI	DOI	NNP
cord-003130-p2h8p5bm	6	3	:	:	:
cord-003130-p2h8p5bm	7	1	10.3390	10.3390	CD
cord-003130-p2h8p5bm	7	2	/	/	SYM
cord-003130-p2h8p5bm	7	3	v10070340	v10070340	NN
cord-003130-p2h8p5bm	7	4	sha	sha	NNP
cord-003130-p2h8p5bm	7	5	:	:	:
cord-003130-p2h8p5bm	7	6	86ba599c91bdbd03345c42fab209766f19f3c5dc	86ba599c91bdbd03345c42fab209766f19f3c5dc	CD
cord-003130-p2h8p5bm	7	7	doc_id	doc_id	CD
cord-003130-p2h8p5bm	7	8	:	:	:
cord-003130-p2h8p5bm	7	9	3130	3130	CD
cord-003130-p2h8p5bm	7	10	cord_uid	cord_uid	NN
cord-003130-p2h8p5bm	7	11	:	:	:
cord-003130-p2h8p5bm	8	1	p2h8p5bm	p2h8p5bm	NNP
cord-003130-p2h8p5bm	8	2	Flaviviruses	Flaviviruses	NNP
cord-003130-p2h8p5bm	8	3	are	be	VBP
cord-003130-p2h8p5bm	8	4	globally	globally	RB
cord-003130-p2h8p5bm	8	5	distributed	distribute	VBN
cord-003130-p2h8p5bm	8	6	pathogens	pathogen	NNS
cord-003130-p2h8p5bm	8	7	causing	cause	VBG
cord-003130-p2h8p5bm	8	8	millions	million	NNS
cord-003130-p2h8p5bm	8	9	of	of	IN
cord-003130-p2h8p5bm	8	10	human	human	JJ
cord-003130-p2h8p5bm	8	11	infections	infection	NNS
cord-003130-p2h8p5bm	8	12	every	every	DT
cord-003130-p2h8p5bm	8	13	year	year	NN
cord-003130-p2h8p5bm	8	14	.	.	.
cord-003130-p2h8p5bm	9	1	Flaviviruses	flavivirus	NNS
cord-003130-p2h8p5bm	9	2	are	be	VBP
cord-003130-p2h8p5bm	9	3	arthropod	arthropod	NN
cord-003130-p2h8p5bm	9	4	-	-	HYPH
cord-003130-p2h8p5bm	9	5	borne	bear	VBN
cord-003130-p2h8p5bm	9	6	viruses	virus	NNS
cord-003130-p2h8p5bm	9	7	and	and	CC
cord-003130-p2h8p5bm	9	8	are	be	VBP
cord-003130-p2h8p5bm	9	9	mainly	mainly	RB
cord-003130-p2h8p5bm	9	10	transmitted	transmit	VBN
cord-003130-p2h8p5bm	9	11	by	by	IN
cord-003130-p2h8p5bm	9	12	either	either	DT
cord-003130-p2h8p5bm	9	13	ticks	tick	NNS
cord-003130-p2h8p5bm	9	14	or	or	CC
cord-003130-p2h8p5bm	9	15	mosquitoes	mosquito	NNS
cord-003130-p2h8p5bm	9	16	.	.	.
cord-003130-p2h8p5bm	10	1	Mosquito	mosquito	NN
cord-003130-p2h8p5bm	10	2	-	-	HYPH
cord-003130-p2h8p5bm	10	3	borne	bear	VBN
cord-003130-p2h8p5bm	10	4	flaviviruses	flavivirus	NNS
cord-003130-p2h8p5bm	10	5	and	and	CC
cord-003130-p2h8p5bm	10	6	their	-PRON-	PRP$
cord-003130-p2h8p5bm	10	7	interactions	interaction	NNS
cord-003130-p2h8p5bm	10	8	with	with	IN
cord-003130-p2h8p5bm	10	9	the	the	DT
cord-003130-p2h8p5bm	10	10	innate	innate	JJ
cord-003130-p2h8p5bm	10	11	immune	immune	JJ
cord-003130-p2h8p5bm	10	12	response	response	NN
cord-003130-p2h8p5bm	10	13	have	have	VBP
cord-003130-p2h8p5bm	10	14	been	be	VBN
cord-003130-p2h8p5bm	10	15	well	well	RB
cord-003130-p2h8p5bm	10	16	-	-	HYPH
cord-003130-p2h8p5bm	10	17	studied	study	VBN
cord-003130-p2h8p5bm	10	18	and	and	CC
cord-003130-p2h8p5bm	10	19	reviewed	review	VBN
cord-003130-p2h8p5bm	10	20	extensively	extensively	RB
cord-003130-p2h8p5bm	10	21	,	,	,
cord-003130-p2h8p5bm	10	22	thus	thus	RB
cord-003130-p2h8p5bm	10	23	this	this	DT
cord-003130-p2h8p5bm	10	24	review	review	NN
cord-003130-p2h8p5bm	10	25	will	will	MD
cord-003130-p2h8p5bm	10	26	discuss	discuss	VB
cord-003130-p2h8p5bm	10	27	tick	tick	VB
cord-003130-p2h8p5bm	10	28	-	-	HYPH
cord-003130-p2h8p5bm	10	29	borne	bear	VBN
cord-003130-p2h8p5bm	10	30	flaviviruses	flavivirus	NNS
cord-003130-p2h8p5bm	10	31	and	and	CC
cord-003130-p2h8p5bm	10	32	their	-PRON-	PRP$
cord-003130-p2h8p5bm	10	33	interactions	interaction	NNS
cord-003130-p2h8p5bm	10	34	with	with	IN
cord-003130-p2h8p5bm	10	35	the	the	DT
cord-003130-p2h8p5bm	10	36	host	host	NN
cord-003130-p2h8p5bm	10	37	innate	innate	JJ
cord-003130-p2h8p5bm	10	38	immune	immune	JJ
cord-003130-p2h8p5bm	10	39	response	response	NN
cord-003130-p2h8p5bm	10	40	.	.	.
cord-003130-p2h8p5bm	11	1	Tick	tick	VB
cord-003130-p2h8p5bm	11	2	-	-	HYPH
cord-003130-p2h8p5bm	11	3	borne	bear	VBN
cord-003130-p2h8p5bm	11	4	flaviviruses	flavivirus	NNS
cord-003130-p2h8p5bm	11	5	(	(	-LRB-
cord-003130-p2h8p5bm	11	6	TBFV	TBFV	NNP
cord-003130-p2h8p5bm	11	7	)	)	-RRB-
cord-003130-p2h8p5bm	11	8	,	,	,
cord-003130-p2h8p5bm	11	9	Flaviviridae	Flaviviridae	NNP
cord-003130-p2h8p5bm	11	10	family	family	NN
cord-003130-p2h8p5bm	11	11	,	,	,
cord-003130-p2h8p5bm	11	12	includes	include	VBZ
cord-003130-p2h8p5bm	11	13	many	many	JJ
cord-003130-p2h8p5bm	11	14	pathogens	pathogen	NNS
cord-003130-p2h8p5bm	11	15	causing	cause	VBG
cord-003130-p2h8p5bm	11	16	severe	severe	JJ
cord-003130-p2h8p5bm	11	17	human	human	JJ
cord-003130-p2h8p5bm	11	18	disease	disease	NN
cord-003130-p2h8p5bm	11	19	,	,	,
cord-003130-p2h8p5bm	11	20	ranging	range	VBG
cord-003130-p2h8p5bm	11	21	from	from	IN
cord-003130-p2h8p5bm	11	22	mild	mild	JJ
cord-003130-p2h8p5bm	11	23	fever	fever	NN
cord-003130-p2h8p5bm	11	24	to	to	IN
cord-003130-p2h8p5bm	11	25	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	11	26	and	and	CC
cord-003130-p2h8p5bm	11	27	hemorrhagic	hemorrhagic	JJ
cord-003130-p2h8p5bm	11	28	fever	fever	NN
cord-003130-p2h8p5bm	11	29	.	.	.
cord-003130-p2h8p5bm	12	1	There	there	EX
cord-003130-p2h8p5bm	12	2	are	be	VBP
cord-003130-p2h8p5bm	12	3	more	more	JJR
cord-003130-p2h8p5bm	12	4	than	than	IN
cord-003130-p2h8p5bm	12	5	70	70	CD
cord-003130-p2h8p5bm	12	6	viruses	virus	NNS
cord-003130-p2h8p5bm	12	7	in	in	IN
cord-003130-p2h8p5bm	12	8	the	the	DT
cord-003130-p2h8p5bm	12	9	genus	genus	NN
cord-003130-p2h8p5bm	12	10	flavivirus	flavivirus	NNP
cord-003130-p2h8p5bm	12	11	,	,	,
cord-003130-p2h8p5bm	12	12	and	and	CC
cord-003130-p2h8p5bm	12	13	they	-PRON-	PRP
cord-003130-p2h8p5bm	12	14	are	be	VBP
cord-003130-p2h8p5bm	12	15	transmitted	transmit	VBN
cord-003130-p2h8p5bm	12	16	by	by	IN
cord-003130-p2h8p5bm	12	17	arthropods	arthropod	NNS
cord-003130-p2h8p5bm	12	18	such	such	JJ
cord-003130-p2h8p5bm	12	19	as	as	IN
cord-003130-p2h8p5bm	12	20	mosquitoes	mosquito	NNS
cord-003130-p2h8p5bm	12	21	(	(	-LRB-
cord-003130-p2h8p5bm	12	22	dengue	dengue	NN
cord-003130-p2h8p5bm	12	23	virus	virus	NN
cord-003130-p2h8p5bm	12	24	(	(	-LRB-
cord-003130-p2h8p5bm	12	25	DENV	DENV	NNP
cord-003130-p2h8p5bm	12	26	)	)	-RRB-
cord-003130-p2h8p5bm	12	27	,	,	,
cord-003130-p2h8p5bm	12	28	Japanese	japanese	JJ
cord-003130-p2h8p5bm	12	29	encephalitis	encephalitis	RB
cord-003130-p2h8p5bm	12	30	virus	virus	NN
cord-003130-p2h8p5bm	12	31	(	(	-LRB-
cord-003130-p2h8p5bm	12	32	JEV	JEV	NNP
cord-003130-p2h8p5bm	12	33	)	)	-RRB-
cord-003130-p2h8p5bm	12	34	and	and	CC
cord-003130-p2h8p5bm	12	35	West	West	NNP
cord-003130-p2h8p5bm	12	36	Nile	Nile	NNP
cord-003130-p2h8p5bm	12	37	virus	virus	NN
cord-003130-p2h8p5bm	12	38	(	(	-LRB-
cord-003130-p2h8p5bm	12	39	WNV	WNV	NNP
cord-003130-p2h8p5bm	12	40	)	)	-RRB-
cord-003130-p2h8p5bm	12	41	,	,	,
cord-003130-p2h8p5bm	12	42	yellow	yellow	JJ
cord-003130-p2h8p5bm	12	43	fever	fever	NN
cord-003130-p2h8p5bm	12	44	virus	virus	NN
cord-003130-p2h8p5bm	12	45	(	(	-LRB-
cord-003130-p2h8p5bm	12	46	YFV	YFV	NNP
cord-003130-p2h8p5bm	12	47	)	)	-RRB-
cord-003130-p2h8p5bm	12	48	,	,	,
cord-003130-p2h8p5bm	12	49	and	and	CC
cord-003130-p2h8p5bm	12	50	Zika	Zika	NNP
cord-003130-p2h8p5bm	12	51	virus	virus	NN
cord-003130-p2h8p5bm	12	52	(	(	-LRB-
cord-003130-p2h8p5bm	12	53	ZIKV	ZIKV	NNP
cord-003130-p2h8p5bm	12	54	)	)	-RRB-
cord-003130-p2h8p5bm	12	55	and	and	CC
cord-003130-p2h8p5bm	12	56	ticks	tick	NNS
cord-003130-p2h8p5bm	12	57	(	(	-LRB-
cord-003130-p2h8p5bm	12	58	tick	tick	VB
cord-003130-p2h8p5bm	12	59	-	-	HYPH
cord-003130-p2h8p5bm	12	60	borne	bear	VBN
cord-003130-p2h8p5bm	12	61	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	12	62	virus	virus	NN
cord-003130-p2h8p5bm	12	63	(	(	-LRB-
cord-003130-p2h8p5bm	12	64	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	12	65	)	)	-RRB-
cord-003130-p2h8p5bm	12	66	,	,	,
cord-003130-p2h8p5bm	12	67	Langat	Langat	NNP
cord-003130-p2h8p5bm	12	68	virus	virus	NN
cord-003130-p2h8p5bm	12	69	(	(	-LRB-
cord-003130-p2h8p5bm	12	70	LGTV	LGTV	NNP
cord-003130-p2h8p5bm	12	71	)	)	-RRB-
cord-003130-p2h8p5bm	12	72	,	,	,
cord-003130-p2h8p5bm	12	73	Kyasanur	Kyasanur	NNP
cord-003130-p2h8p5bm	12	74	forest	forest	NN
cord-003130-p2h8p5bm	12	75	disease	disease	NN
cord-003130-p2h8p5bm	12	76	virus	virus	NN
cord-003130-p2h8p5bm	12	77	(	(	-LRB-
cord-003130-p2h8p5bm	12	78	KFDV	KFDV	NNP
cord-003130-p2h8p5bm	12	79	)	)	-RRB-
cord-003130-p2h8p5bm	12	80	,	,	,
cord-003130-p2h8p5bm	12	81	Omsk	Omsk	NNP
cord-003130-p2h8p5bm	12	82	hemorrhagic	hemorrhagic	JJ
cord-003130-p2h8p5bm	12	83	fever	fever	NN
cord-003130-p2h8p5bm	12	84	virus	virus	NN
cord-003130-p2h8p5bm	12	85	(	(	-LRB-
cord-003130-p2h8p5bm	12	86	OHFV	OHFV	NNP
cord-003130-p2h8p5bm	12	87	)	)	-RRB-
cord-003130-p2h8p5bm	12	88	,	,	,
cord-003130-p2h8p5bm	12	89	Powassan	Powassan	NNP
cord-003130-p2h8p5bm	12	90	virus	virus	NN
cord-003130-p2h8p5bm	12	91	(	(	-LRB-
cord-003130-p2h8p5bm	12	92	POWV	POWV	NNP
cord-003130-p2h8p5bm	12	93	)	)	-RRB-
cord-003130-p2h8p5bm	12	94	,	,	,
cord-003130-p2h8p5bm	12	95	and	and	CC
cord-003130-p2h8p5bm	12	96	Louping	Louping	NNP
cord-003130-p2h8p5bm	12	97	-	-	HYPH
cord-003130-p2h8p5bm	12	98	ill	ill	JJ
cord-003130-p2h8p5bm	12	99	virus	virus	NN
cord-003130-p2h8p5bm	12	100	(	(	-LRB-
cord-003130-p2h8p5bm	12	101	LIV	LIV	NNP
cord-003130-p2h8p5bm	12	102	)	)	-RRB-
cord-003130-p2h8p5bm	12	103	)	)	-RRB-
cord-003130-p2h8p5bm	13	1	[	[	-LRB-
cord-003130-p2h8p5bm	13	2	1	1	CD
cord-003130-p2h8p5bm	13	3	]	]	-RRB-
cord-003130-p2h8p5bm	13	4	[	[	-LRB-
cord-003130-p2h8p5bm	13	5	2	2	CD
cord-003130-p2h8p5bm	13	6	]	]	-RRB-
cord-003130-p2h8p5bm	13	7	[	[	-LRB-
cord-003130-p2h8p5bm	13	8	3	3	CD
cord-003130-p2h8p5bm	13	9	]	]	-RRB-
cord-003130-p2h8p5bm	13	10	[	[	-LRB-
cord-003130-p2h8p5bm	13	11	4	4	CD
cord-003130-p2h8p5bm	13	12	]	]	-RRB-
cord-003130-p2h8p5bm	13	13	[	[	-LRB-
cord-003130-p2h8p5bm	13	14	5	5	CD
cord-003130-p2h8p5bm	13	15	]	]	-RRB-
cord-003130-p2h8p5bm	13	16	.	.	.
cord-003130-p2h8p5bm	14	1	Among	among	IN
cord-003130-p2h8p5bm	14	2	the	the	DT
cord-003130-p2h8p5bm	14	3	TBFVs	tbfv	NNS
cord-003130-p2h8p5bm	14	4	,	,	,
cord-003130-p2h8p5bm	14	5	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	14	6	,	,	,
cord-003130-p2h8p5bm	14	7	POWV	POWV	NNP
cord-003130-p2h8p5bm	14	8	,	,	,
cord-003130-p2h8p5bm	14	9	and	and	CC
cord-003130-p2h8p5bm	14	10	LIV	LIV	NNP
cord-003130-p2h8p5bm	14	11	are	be	VBP
cord-003130-p2h8p5bm	14	12	encephalitic	encephalitic	JJ
cord-003130-p2h8p5bm	14	13	,	,	,
cord-003130-p2h8p5bm	14	14	whereas	whereas	IN
cord-003130-p2h8p5bm	14	15	OHFV	OHFV	NNP
cord-003130-p2h8p5bm	14	16	and	and	CC
cord-003130-p2h8p5bm	14	17	KFDV	KFDV	NNP
cord-003130-p2h8p5bm	14	18	are	be	VBP
cord-003130-p2h8p5bm	14	19	hemorrhagic	hemorrhagic	JJ
cord-003130-p2h8p5bm	14	20	viruses	virus	NNS
cord-003130-p2h8p5bm	14	21	.	.	.
cord-003130-p2h8p5bm	15	1	There	there	EX
cord-003130-p2h8p5bm	15	2	are	be	VBP
cord-003130-p2h8p5bm	15	3	general	general	JJ
cord-003130-p2h8p5bm	15	4	features	feature	NNS
cord-003130-p2h8p5bm	15	5	that	that	WDT
cord-003130-p2h8p5bm	15	6	distinguish	distinguish	VBP
cord-003130-p2h8p5bm	15	7	TBFV	tbfv	NN
cord-003130-p2h8p5bm	15	8	from	from	IN
cord-003130-p2h8p5bm	15	9	mosquito	mosquito	NN
cord-003130-p2h8p5bm	15	10	-	-	HYPH
cord-003130-p2h8p5bm	15	11	borne	bear	VBN
cord-003130-p2h8p5bm	15	12	.	.	.
cord-003130-p2h8p5bm	16	1	One	one	CD
cord-003130-p2h8p5bm	16	2	such	such	JJ
cord-003130-p2h8p5bm	16	3	feature	feature	NN
cord-003130-p2h8p5bm	16	4	is	be	VBZ
cord-003130-p2h8p5bm	16	5	that	that	IN
cord-003130-p2h8p5bm	16	6	tick	tick	NN
cord-003130-p2h8p5bm	16	7	-	-	HYPH
cord-003130-p2h8p5bm	16	8	borne	bear	VBN
cord-003130-p2h8p5bm	16	9	viruses	virus	NNS
cord-003130-p2h8p5bm	16	10	tend	tend	VBP
cord-003130-p2h8p5bm	16	11	to	to	TO
cord-003130-p2h8p5bm	16	12	persist	persist	VB
cord-003130-p2h8p5bm	16	13	in	in	IN
cord-003130-p2h8p5bm	16	14	certain	certain	JJ
cord-003130-p2h8p5bm	16	15	stable	stable	JJ
cord-003130-p2h8p5bm	16	16	foci	foci	NN
cord-003130-p2h8p5bm	16	17	whereas	whereas	IN
cord-003130-p2h8p5bm	16	18	mosquito	mosquito	NN
cord-003130-p2h8p5bm	16	19	-	-	HYPH
cord-003130-p2h8p5bm	16	20	borne	bear	VBN
cord-003130-p2h8p5bm	16	21	viruses	virus	NNS
cord-003130-p2h8p5bm	16	22	may	may	MD
cord-003130-p2h8p5bm	16	23	suddenly	suddenly	RB
cord-003130-p2h8p5bm	16	24	emerge	emerge	VB
cord-003130-p2h8p5bm	16	25	and	and	CC
cord-003130-p2h8p5bm	16	26	they	-PRON-	PRP
cord-003130-p2h8p5bm	16	27	can	can	MD
cord-003130-p2h8p5bm	16	28	rapidly	rapidly	RB
cord-003130-p2h8p5bm	16	29	spread	spread	VB
cord-003130-p2h8p5bm	16	30	to	to	IN
cord-003130-p2h8p5bm	16	31	new	new	JJ
cord-003130-p2h8p5bm	16	32	areas	area	NNS
cord-003130-p2h8p5bm	16	33	and	and	CC
cord-003130-p2h8p5bm	16	34	continents	continent	NNS
cord-003130-p2h8p5bm	16	35	causing	cause	VBG
cord-003130-p2h8p5bm	16	36	large	large	JJ
cord-003130-p2h8p5bm	16	37	epidemics	epidemic	NNS
cord-003130-p2h8p5bm	16	38	[	[	-LRB-
cord-003130-p2h8p5bm	16	39	6	6	CD
cord-003130-p2h8p5bm	16	40	]	]	-RRB-
cord-003130-p2h8p5bm	16	41	[	[	-LRB-
cord-003130-p2h8p5bm	16	42	7	7	CD
cord-003130-p2h8p5bm	16	43	]	]	-RRB-
cord-003130-p2h8p5bm	16	44	[	[	-LRB-
cord-003130-p2h8p5bm	16	45	8	8	CD
cord-003130-p2h8p5bm	16	46	]	]	-RRB-
cord-003130-p2h8p5bm	16	47	[	[	-LRB-
cord-003130-p2h8p5bm	16	48	9	9	CD
cord-003130-p2h8p5bm	16	49	]	]	-RRB-
cord-003130-p2h8p5bm	16	50	[	[	-LRB-
cord-003130-p2h8p5bm	16	51	10	10	CD
cord-003130-p2h8p5bm	16	52	]	]	-RRB-
cord-003130-p2h8p5bm	16	53	[	[	-LRB-
cord-003130-p2h8p5bm	16	54	11	11	CD
cord-003130-p2h8p5bm	16	55	]	]	-RRB-
cord-003130-p2h8p5bm	16	56	.	.	.
cord-003130-p2h8p5bm	17	1	Mosquito	mosquito	NN
cord-003130-p2h8p5bm	17	2	-	-	HYPH
cord-003130-p2h8p5bm	17	3	borne	bear	VBN
cord-003130-p2h8p5bm	17	4	flaviviruses	flavivirus	NNS
cord-003130-p2h8p5bm	17	5	are	be	VBP
cord-003130-p2h8p5bm	17	6	transmitted	transmit	VBN
cord-003130-p2h8p5bm	17	7	horizontally	horizontally	RB
cord-003130-p2h8p5bm	17	8	from	from	IN
cord-003130-p2h8p5bm	17	9	mosquito	mosquito	NN
cord-003130-p2h8p5bm	17	10	to	to	IN
cord-003130-p2h8p5bm	17	11	vertebrate	vertebrate	NN
cord-003130-p2h8p5bm	17	12	to	to	IN
cord-003130-p2h8p5bm	17	13	mosquito	mosquito	NN
cord-003130-p2h8p5bm	17	14	,	,	,
cord-003130-p2h8p5bm	17	15	and	and	CC
cord-003130-p2h8p5bm	17	16	for	for	IN
cord-003130-p2h8p5bm	17	17	some	some	DT
cord-003130-p2h8p5bm	17	18	viruses	virus	NNS
cord-003130-p2h8p5bm	17	19	,	,	,
cord-003130-p2h8p5bm	17	20	humans	human	NNS
cord-003130-p2h8p5bm	17	21	act	act	VBP
cord-003130-p2h8p5bm	17	22	as	as	IN
cord-003130-p2h8p5bm	17	23	the	the	DT
cord-003130-p2h8p5bm	17	24	amplifying	amplify	VBG
cord-003130-p2h8p5bm	17	25	host	host	NN
cord-003130-p2h8p5bm	17	26	[	[	-LRB-
cord-003130-p2h8p5bm	17	27	12	12	CD
cord-003130-p2h8p5bm	17	28	]	]	-RRB-
cord-003130-p2h8p5bm	17	29	[	[	-LRB-
cord-003130-p2h8p5bm	17	30	13	13	CD
cord-003130-p2h8p5bm	17	31	]	]	-RRB-
cord-003130-p2h8p5bm	17	32	[	[	-LRB-
cord-003130-p2h8p5bm	17	33	14	14	CD
cord-003130-p2h8p5bm	17	34	]	]	-RRB-
cord-003130-p2h8p5bm	17	35	.	.	.
cord-003130-p2h8p5bm	18	1	Mosquitoes	mosquito	NNS
cord-003130-p2h8p5bm	18	2	have	have	VBP
cord-003130-p2h8p5bm	18	3	a	a	DT
cord-003130-p2h8p5bm	18	4	short	short	JJ
cord-003130-p2h8p5bm	18	5	life	life	NN
cord-003130-p2h8p5bm	18	6	compared	compare	VBN
cord-003130-p2h8p5bm	18	7	to	to	IN
cord-003130-p2h8p5bm	18	8	ticks	tick	NNS
cord-003130-p2h8p5bm	18	9	,	,	,
cord-003130-p2h8p5bm	18	10	as	as	IN
cord-003130-p2h8p5bm	18	11	it	-PRON-	PRP
cord-003130-p2h8p5bm	18	12	can	can	MD
cord-003130-p2h8p5bm	18	13	take	take	VB
cord-003130-p2h8p5bm	18	14	several	several	JJ
cord-003130-p2h8p5bm	18	15	years	year	NNS
cord-003130-p2h8p5bm	18	16	for	for	IN
cord-003130-p2h8p5bm	18	17	a	a	DT
cord-003130-p2h8p5bm	18	18	tick	tick	NN
cord-003130-p2h8p5bm	18	19	to	to	TO
cord-003130-p2h8p5bm	18	20	develop	develop	VB
cord-003130-p2h8p5bm	18	21	from	from	IN
cord-003130-p2h8p5bm	18	22	egg	egg	NN
cord-003130-p2h8p5bm	18	23	to	to	IN
cord-003130-p2h8p5bm	18	24	adult	adult	NN
cord-003130-p2h8p5bm	18	25	[	[	-LRB-
cord-003130-p2h8p5bm	18	26	15	15	CD
cord-003130-p2h8p5bm	18	27	]	]	-RRB-
cord-003130-p2h8p5bm	18	28	.	.	.
cord-003130-p2h8p5bm	19	1	Ticks	tick	NNS
cord-003130-p2h8p5bm	19	2	also	also	RB
cord-003130-p2h8p5bm	19	3	only	only	RB
cord-003130-p2h8p5bm	19	4	take	take	VBP
cord-003130-p2h8p5bm	19	5	one	one	CD
cord-003130-p2h8p5bm	19	6	blood	blood	NN
cord-003130-p2h8p5bm	19	7	meal	meal	NN
cord-003130-p2h8p5bm	19	8	at	at	IN
cord-003130-p2h8p5bm	19	9	each	each	DT
cord-003130-p2h8p5bm	19	10	of	of	IN
cord-003130-p2h8p5bm	19	11	their	-PRON-	PRP$
cord-003130-p2h8p5bm	19	12	life	life	NN
cord-003130-p2h8p5bm	19	13	stages	stage	NNS
cord-003130-p2h8p5bm	19	14	,	,	,
cord-003130-p2h8p5bm	19	15	larvae	larva	NNS
cord-003130-p2h8p5bm	19	16	,	,	,
cord-003130-p2h8p5bm	19	17	nymph	nymph	NN
cord-003130-p2h8p5bm	19	18	,	,	,
cord-003130-p2h8p5bm	19	19	and	and	CC
cord-003130-p2h8p5bm	19	20	adult	adult	NN
cord-003130-p2h8p5bm	19	21	,	,	,
cord-003130-p2h8p5bm	19	22	this	this	DT
cord-003130-p2h8p5bm	19	23	means	mean	VBZ
cord-003130-p2h8p5bm	19	24	that	that	IN
cord-003130-p2h8p5bm	19	25	tick	tick	NN
cord-003130-p2h8p5bm	19	26	-	-	HYPH
cord-003130-p2h8p5bm	19	27	borne	bear	VBN
cord-003130-p2h8p5bm	19	28	viruses	virus	NNS
cord-003130-p2h8p5bm	19	29	need	need	VBP
cord-003130-p2h8p5bm	19	30	to	to	TO
cord-003130-p2h8p5bm	19	31	be	be	VB
cord-003130-p2h8p5bm	19	32	maintained	maintain	VBN
cord-003130-p2h8p5bm	19	33	in	in	IN
cord-003130-p2h8p5bm	19	34	infected	infected	JJ
cord-003130-p2h8p5bm	19	35	ticks	tick	NNS
cord-003130-p2h8p5bm	19	36	during	during	IN
cord-003130-p2h8p5bm	19	37	a	a	DT
cord-003130-p2h8p5bm	19	38	very	very	RB
cord-003130-p2h8p5bm	19	39	long	long	JJ
cord-003130-p2h8p5bm	19	40	time	time	NN
cord-003130-p2h8p5bm	19	41	[	[	-LRB-
cord-003130-p2h8p5bm	19	42	16	16	CD
cord-003130-p2h8p5bm	19	43	]	]	-RRB-
cord-003130-p2h8p5bm	19	44	.	.	.
cord-003130-p2h8p5bm	20	1	Thus	thus	RB
cord-003130-p2h8p5bm	20	2	,	,	,
cord-003130-p2h8p5bm	20	3	replication	replication	NN
cord-003130-p2h8p5bm	20	4	in	in	IN
cord-003130-p2h8p5bm	20	5	ticks	tick	NNS
cord-003130-p2h8p5bm	20	6	needs	need	VBZ
cord-003130-p2h8p5bm	20	7	to	to	TO
cord-003130-p2h8p5bm	20	8	be	be	VB
cord-003130-p2h8p5bm	20	9	lower	low	JJR
cord-003130-p2h8p5bm	20	10	compared	compare	VBN
cord-003130-p2h8p5bm	20	11	to	to	IN
cord-003130-p2h8p5bm	20	12	mosquitoes	mosquito	NNS
cord-003130-p2h8p5bm	20	13	,	,	,
cord-003130-p2h8p5bm	20	14	which	which	WDT
cord-003130-p2h8p5bm	20	15	have	have	VBP
cord-003130-p2h8p5bm	20	16	higher	high	JJR
cord-003130-p2h8p5bm	20	17	viral	viral	JJ
cord-003130-p2h8p5bm	20	18	turnover	turnover	NN
cord-003130-p2h8p5bm	20	19	and	and	CC
cord-003130-p2h8p5bm	20	20	a	a	DT
cord-003130-p2h8p5bm	20	21	faster	fast	JJR
cord-003130-p2h8p5bm	20	22	generation	generation	NN
cord-003130-p2h8p5bm	20	23	cycle	cycle	NN
cord-003130-p2h8p5bm	20	24	,	,	,
cord-003130-p2h8p5bm	20	25	this	this	DT
cord-003130-p2h8p5bm	20	26	also	also	RB
cord-003130-p2h8p5bm	20	27	contributes	contribute	VBZ
cord-003130-p2h8p5bm	20	28	to	to	IN
cord-003130-p2h8p5bm	20	29	the	the	DT
cord-003130-p2h8p5bm	20	30	high	high	JJ
cord-003130-p2h8p5bm	20	31	mutation	mutation	NN
cord-003130-p2h8p5bm	20	32	rate	rate	NN
cord-003130-p2h8p5bm	20	33	in	in	IN
cord-003130-p2h8p5bm	20	34	mosquito	mosquito	NN
cord-003130-p2h8p5bm	20	35	-	-	HYPH
cord-003130-p2h8p5bm	20	36	borne	bear	VBN
cord-003130-p2h8p5bm	20	37	flaviviruses	flavivirus	NNS
cord-003130-p2h8p5bm	20	38	,	,	,
cord-003130-p2h8p5bm	20	39	and	and	CC
cord-003130-p2h8p5bm	20	40	relative	relative	JJ
cord-003130-p2h8p5bm	20	41	stable	stable	JJ
cord-003130-p2h8p5bm	20	42	genomes	genome	NNS
cord-003130-p2h8p5bm	20	43	of	of	IN
cord-003130-p2h8p5bm	20	44	TBFVs	tbfv	NNS
cord-003130-p2h8p5bm	20	45	[	[	-LRB-
cord-003130-p2h8p5bm	20	46	17	17	CD
cord-003130-p2h8p5bm	20	47	,	,	,
cord-003130-p2h8p5bm	20	48	18	18	CD
cord-003130-p2h8p5bm	20	49	]	]	-RRB-
cord-003130-p2h8p5bm	20	50	.	.	.
cord-003130-p2h8p5bm	21	1	Infection	infection	NN
cord-003130-p2h8p5bm	21	2	of	of	IN
cord-003130-p2h8p5bm	21	3	tick	tick	NN
cord-003130-p2h8p5bm	21	4	-	-	HYPH
cord-003130-p2h8p5bm	21	5	borne	bear	VBN
cord-003130-p2h8p5bm	21	6	flaviviruses	flavivirus	NNS
cord-003130-p2h8p5bm	21	7	usually	usually	RB
cord-003130-p2h8p5bm	21	8	cause	cause	VBP
cord-003130-p2h8p5bm	21	9	a	a	DT
cord-003130-p2h8p5bm	21	10	short	short	JJ
cord-003130-p2h8p5bm	21	11	viremia	viremia	NN
cord-003130-p2h8p5bm	21	12	in	in	IN
cord-003130-p2h8p5bm	21	13	humans	human	NNS
cord-003130-p2h8p5bm	21	14	and	and	CC
cord-003130-p2h8p5bm	21	15	larger	large	JJR
cord-003130-p2h8p5bm	21	16	vertebrates	vertebrate	NNS
cord-003130-p2h8p5bm	21	17	.	.	.
cord-003130-p2h8p5bm	22	1	This	this	DT
cord-003130-p2h8p5bm	22	2	route	route	NN
cord-003130-p2h8p5bm	22	3	of	of	IN
cord-003130-p2h8p5bm	22	4	transmission	transmission	NN
cord-003130-p2h8p5bm	22	5	has	have	VBZ
cord-003130-p2h8p5bm	22	6	been	be	VBN
cord-003130-p2h8p5bm	22	7	described	describe	VBN
cord-003130-p2h8p5bm	22	8	as	as	IN
cord-003130-p2h8p5bm	22	9	less	less	RBR
cord-003130-p2h8p5bm	22	10	important	important	JJ
cord-003130-p2h8p5bm	22	11	in	in	IN
cord-003130-p2h8p5bm	22	12	tick	tick	NN
cord-003130-p2h8p5bm	22	13	-	-	HYPH
cord-003130-p2h8p5bm	22	14	borne	bear	VBN
cord-003130-p2h8p5bm	22	15	flavivirus	flavivirus	JJ
cord-003130-p2h8p5bm	22	16	infection	infection	NN
cord-003130-p2h8p5bm	22	17	[	[	-LRB-
cord-003130-p2h8p5bm	22	18	19	19	CD
cord-003130-p2h8p5bm	22	19	]	]	-RRB-
cord-003130-p2h8p5bm	22	20	,	,	,
cord-003130-p2h8p5bm	22	21	instead	instead	RB
cord-003130-p2h8p5bm	22	22	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	22	23	has	have	VBZ
cord-003130-p2h8p5bm	22	24	been	be	VBN
cord-003130-p2h8p5bm	22	25	shown	show	VBN
cord-003130-p2h8p5bm	22	26	to	to	TO
cord-003130-p2h8p5bm	22	27	be	be	VB
cord-003130-p2h8p5bm	22	28	transmitted	transmit	VBN
cord-003130-p2h8p5bm	22	29	by	by	IN
cord-003130-p2h8p5bm	22	30	viremic	viremic	JJ
cord-003130-p2h8p5bm	22	31	rodents	rodent	NNS
cord-003130-p2h8p5bm	22	32	and	and	CC
cord-003130-p2h8p5bm	22	33	among	among	IN
cord-003130-p2h8p5bm	22	34	co	co	NN
cord-003130-p2h8p5bm	22	35	-	-	JJ
cord-003130-p2h8p5bm	22	36	feeding	feeding	JJ
cord-003130-p2h8p5bm	22	37	ticks	tick	NNS
cord-003130-p2h8p5bm	22	38	without	without	IN
cord-003130-p2h8p5bm	22	39	viremia	viremia	NN
cord-003130-p2h8p5bm	22	40	[	[	-LRB-
cord-003130-p2h8p5bm	22	41	20	20	CD
cord-003130-p2h8p5bm	22	42	]	]	-RRB-
cord-003130-p2h8p5bm	22	43	.	.	.
cord-003130-p2h8p5bm	23	1	Humans	human	NNS
cord-003130-p2h8p5bm	23	2	act	act	VBP
cord-003130-p2h8p5bm	23	3	as	as	IN
cord-003130-p2h8p5bm	23	4	dead	dead	JJ
cord-003130-p2h8p5bm	23	5	-	-	HYPH
cord-003130-p2h8p5bm	23	6	end	end	NN
cord-003130-p2h8p5bm	23	7	hosts	host	NNS
cord-003130-p2h8p5bm	23	8	since	since	IN
cord-003130-p2h8p5bm	23	9	they	-PRON-	PRP
cord-003130-p2h8p5bm	23	10	do	do	VBP
cord-003130-p2h8p5bm	23	11	not	not	RB
cord-003130-p2h8p5bm	23	12	produce	produce	VB
cord-003130-p2h8p5bm	23	13	high	high	JJ
cord-003130-p2h8p5bm	23	14	enough	enough	JJ
cord-003130-p2h8p5bm	23	15	viremia	viremia	NN
cord-003130-p2h8p5bm	23	16	to	to	TO
cord-003130-p2h8p5bm	23	17	transmit	transmit	VB
cord-003130-p2h8p5bm	23	18	the	the	DT
cord-003130-p2h8p5bm	23	19	virus	virus	NN
cord-003130-p2h8p5bm	23	20	to	to	IN
cord-003130-p2h8p5bm	23	21	new	new	JJ
cord-003130-p2h8p5bm	23	22	ticks	tick	NNS
cord-003130-p2h8p5bm	23	23	.	.	.
cord-003130-p2h8p5bm	24	1	According	accord	VBG
cord-003130-p2h8p5bm	24	2	to	to	IN
cord-003130-p2h8p5bm	24	3	phylogenetic	phylogenetic	JJ
cord-003130-p2h8p5bm	24	4	differences	difference	NNS
cord-003130-p2h8p5bm	24	5	,	,	,
cord-003130-p2h8p5bm	24	6	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	24	7	has	have	VBZ
cord-003130-p2h8p5bm	24	8	been	be	VBN
cord-003130-p2h8p5bm	24	9	divided	divide	VBN
cord-003130-p2h8p5bm	24	10	into	into	IN
cord-003130-p2h8p5bm	24	11	three	three	CD
cord-003130-p2h8p5bm	24	12	different	different	JJ
cord-003130-p2h8p5bm	24	13	subtypes	subtype	NNS
cord-003130-p2h8p5bm	24	14	,	,	,
cord-003130-p2h8p5bm	24	15	European	european	JJ
cord-003130-p2h8p5bm	24	16	,	,	,
cord-003130-p2h8p5bm	24	17	Siberian	Siberian	NNP
cord-003130-p2h8p5bm	24	18	,	,	,
cord-003130-p2h8p5bm	24	19	and	and	CC
cord-003130-p2h8p5bm	24	20	Far	Far	NNP
cord-003130-p2h8p5bm	24	21	Eastern	Eastern	NNP
cord-003130-p2h8p5bm	24	22	.	.	.
cord-003130-p2h8p5bm	25	1	The	the	DT
cord-003130-p2h8p5bm	25	2	European	european	JJ
cord-003130-p2h8p5bm	25	3	subtype	subtype	NN
cord-003130-p2h8p5bm	25	4	is	be	VBZ
cord-003130-p2h8p5bm	25	5	mainly	mainly	RB
cord-003130-p2h8p5bm	25	6	transmitted	transmit	VBN
cord-003130-p2h8p5bm	25	7	by	by	IN
cord-003130-p2h8p5bm	25	8	Ixodes	Ixodes	NNP
cord-003130-p2h8p5bm	25	9	ricinus	ricinus	NNP
cord-003130-p2h8p5bm	25	10	,	,	,
cord-003130-p2h8p5bm	25	11	whereas	whereas	IN
cord-003130-p2h8p5bm	25	12	the	the	DT
cord-003130-p2h8p5bm	25	13	Siberian	Siberian	NNP
cord-003130-p2h8p5bm	25	14	and	and	CC
cord-003130-p2h8p5bm	25	15	Far	far	JJ
cord-003130-p2h8p5bm	25	16	Eastern	eastern	JJ
cord-003130-p2h8p5bm	25	17	subtypes	subtype	NNS
cord-003130-p2h8p5bm	25	18	are	be	VBP
cord-003130-p2h8p5bm	25	19	primarily	primarily	RB
cord-003130-p2h8p5bm	25	20	transmitted	transmit	VBN
cord-003130-p2h8p5bm	25	21	by	by	IN
cord-003130-p2h8p5bm	25	22	Ixodes	Ixodes	NNP
cord-003130-p2h8p5bm	25	23	persulcatus	persulcatus	NNP
cord-003130-p2h8p5bm	25	24	[	[	-LRB-
cord-003130-p2h8p5bm	25	25	21	21	CD
cord-003130-p2h8p5bm	25	26	,	,	,
cord-003130-p2h8p5bm	25	27	22	22	CD
cord-003130-p2h8p5bm	25	28	]	]	-RRB-
cord-003130-p2h8p5bm	25	29	.	.	.
cord-003130-p2h8p5bm	26	1	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	26	2	is	be	VBZ
cord-003130-p2h8p5bm	26	3	found	find	VBN
cord-003130-p2h8p5bm	26	4	in	in	IN
cord-003130-p2h8p5bm	26	5	central	central	JJ
cord-003130-p2h8p5bm	26	6	,	,	,
cord-003130-p2h8p5bm	26	7	eastern	eastern	JJ
cord-003130-p2h8p5bm	26	8	,	,	,
cord-003130-p2h8p5bm	26	9	and	and	CC
cord-003130-p2h8p5bm	26	10	northern	northern	JJ
cord-003130-p2h8p5bm	26	11	Europe	Europe	NNP
cord-003130-p2h8p5bm	26	12	and	and	CC
cord-003130-p2h8p5bm	26	13	Asia	Asia	NNP
cord-003130-p2h8p5bm	26	14	(	(	-LRB-
cord-003130-p2h8p5bm	26	15	Figure	figure	NN
cord-003130-p2h8p5bm	26	16	1	1	CD
cord-003130-p2h8p5bm	26	17	)	)	-RRB-
cord-003130-p2h8p5bm	26	18	and	and	CC
cord-003130-p2h8p5bm	26	19	correlates	correlate	VBZ
cord-003130-p2h8p5bm	26	20	with	with	IN
cord-003130-p2h8p5bm	26	21	the	the	DT
cord-003130-p2h8p5bm	26	22	presence	presence	NN
cord-003130-p2h8p5bm	26	23	of	of	IN
cord-003130-p2h8p5bm	26	24	infected	infected	JJ
cord-003130-p2h8p5bm	26	25	ticks	tick	NNS
cord-003130-p2h8p5bm	26	26	.	.	.
cord-003130-p2h8p5bm	27	1	Ixodes	Ixodes	NNP
cord-003130-p2h8p5bm	27	2	ricinus	ricinus	NNP
cord-003130-p2h8p5bm	27	3	is	be	VBZ
cord-003130-p2h8p5bm	27	4	found	find	VBN
cord-003130-p2h8p5bm	27	5	throughout	throughout	IN
cord-003130-p2h8p5bm	27	6	Europe	Europe	NNP
cord-003130-p2h8p5bm	27	7	,	,	,
cord-003130-p2h8p5bm	27	8	whereas	whereas	IN
cord-003130-p2h8p5bm	27	9	Ixodes	Ixodes	NNP
cord-003130-p2h8p5bm	27	10	persulcatus	persulcatus	NN
cord-003130-p2h8p5bm	27	11	is	be	VBZ
cord-003130-p2h8p5bm	27	12	found	find	VBN
cord-003130-p2h8p5bm	27	13	in	in	IN
cord-003130-p2h8p5bm	27	14	Eastern	Eastern	NNP
cord-003130-p2h8p5bm	27	15	Europe	Europe	NNP
cord-003130-p2h8p5bm	27	16	in	in	IN
cord-003130-p2h8p5bm	27	17	the	the	DT
cord-003130-p2h8p5bm	27	18	west	west	NN
cord-003130-p2h8p5bm	27	19	,	,	,
cord-003130-p2h8p5bm	27	20	and	and	CC
cord-003130-p2h8p5bm	27	21	China	China	NNP
cord-003130-p2h8p5bm	27	22	and	and	CC
cord-003130-p2h8p5bm	27	23	Japan	Japan	NNP
cord-003130-p2h8p5bm	27	24	in	in	IN
cord-003130-p2h8p5bm	27	25	the	the	DT
cord-003130-p2h8p5bm	27	26	east	east	NN
cord-003130-p2h8p5bm	27	27	[	[	-LRB-
cord-003130-p2h8p5bm	27	28	23	23	CD
cord-003130-p2h8p5bm	27	29	]	]	-RRB-
cord-003130-p2h8p5bm	27	30	.	.	.
cord-003130-p2h8p5bm	28	1	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	28	2	is	be	VBZ
cord-003130-p2h8p5bm	28	3	considered	consider	VBN
cord-003130-p2h8p5bm	28	4	one	one	CD
cord-003130-p2h8p5bm	28	5	of	of	IN
cord-003130-p2h8p5bm	28	6	the	the	DT
cord-003130-p2h8p5bm	28	7	most	most	RBS
cord-003130-p2h8p5bm	28	8	important	important	JJ
cord-003130-p2h8p5bm	28	9	arboviruses	arbovirus	NNS
cord-003130-p2h8p5bm	28	10	in	in	IN
cord-003130-p2h8p5bm	28	11	central	central	JJ
cord-003130-p2h8p5bm	28	12	and	and	CC
cord-003130-p2h8p5bm	28	13	eastern	eastern	JJ
cord-003130-p2h8p5bm	28	14	European	european	JJ
cord-003130-p2h8p5bm	28	15	countries	country	NNS
cord-003130-p2h8p5bm	28	16	and	and	CC
cord-003130-p2h8p5bm	28	17	in	in	IN
cord-003130-p2h8p5bm	28	18	Russia	Russia	NNP
cord-003130-p2h8p5bm	28	19	,	,	,
cord-003130-p2h8p5bm	28	20	with	with	IN
cord-003130-p2h8p5bm	28	21	about	about	RB
cord-003130-p2h8p5bm	28	22	13,000	13,000	CD
cord-003130-p2h8p5bm	28	23	estimated	estimate	VBN
cord-003130-p2h8p5bm	28	24	human	human	JJ
cord-003130-p2h8p5bm	28	25	cases	case	NNS
cord-003130-p2h8p5bm	28	26	annually	annually	RB
cord-003130-p2h8p5bm	28	27	[	[	-LRB-
cord-003130-p2h8p5bm	28	28	24	24	CD
cord-003130-p2h8p5bm	28	29	]	]	-RRB-
cord-003130-p2h8p5bm	28	30	.	.	.
cord-003130-p2h8p5bm	29	1	In	in	IN
cord-003130-p2h8p5bm	29	2	fact	fact	NN
cord-003130-p2h8p5bm	29	3	,	,	,
cord-003130-p2h8p5bm	29	4	over	over	IN
cord-003130-p2h8p5bm	29	5	the	the	DT
cord-003130-p2h8p5bm	29	6	last	last	JJ
cord-003130-p2h8p5bm	29	7	decade	decade	NN
cord-003130-p2h8p5bm	29	8	there	there	EX
cord-003130-p2h8p5bm	29	9	has	have	VBZ
cord-003130-p2h8p5bm	29	10	been	be	VBN
cord-003130-p2h8p5bm	29	11	an	an	DT
cord-003130-p2h8p5bm	29	12	approximately	approximately	RB
cord-003130-p2h8p5bm	29	13	300	300	CD
cord-003130-p2h8p5bm	29	14	%	%	NN
cord-003130-p2h8p5bm	29	15	increase	increase	NN
cord-003130-p2h8p5bm	29	16	in	in	IN
cord-003130-p2h8p5bm	29	17	the	the	DT
cord-003130-p2h8p5bm	29	18	number	number	NN
cord-003130-p2h8p5bm	29	19	of	of	IN
cord-003130-p2h8p5bm	29	20	TBE	TBE	NNP
cord-003130-p2h8p5bm	29	21	cases	case	NNS
cord-003130-p2h8p5bm	29	22	in	in	IN
cord-003130-p2h8p5bm	29	23	Europe	Europe	NNP
cord-003130-p2h8p5bm	29	24	[	[	-LRB-
cord-003130-p2h8p5bm	29	25	25	25	CD
cord-003130-p2h8p5bm	29	26	]	]	-RRB-
cord-003130-p2h8p5bm	29	27	,	,	,
cord-003130-p2h8p5bm	29	28	and	and	CC
cord-003130-p2h8p5bm	29	29	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	29	30	is	be	VBZ
cord-003130-p2h8p5bm	29	31	currently	currently	RB
cord-003130-p2h8p5bm	29	32	spreading	spread	VBG
cord-003130-p2h8p5bm	29	33	into	into	IN
cord-003130-p2h8p5bm	29	34	new	new	JJ
cord-003130-p2h8p5bm	29	35	regions	region	NNS
cord-003130-p2h8p5bm	29	36	in	in	IN
cord-003130-p2h8p5bm	29	37	France	France	NNP
cord-003130-p2h8p5bm	29	38	,	,	,
cord-003130-p2h8p5bm	29	39	Sweden	Sweden	NNP
cord-003130-p2h8p5bm	29	40	,	,	,
cord-003130-p2h8p5bm	29	41	Norway	Norway	NNP
cord-003130-p2h8p5bm	29	42	,	,	,
cord-003130-p2h8p5bm	29	43	and	and	CC
cord-003130-p2h8p5bm	29	44	Italy	Italy	NNP
cord-003130-p2h8p5bm	29	45	[	[	-LRB-
cord-003130-p2h8p5bm	29	46	26	26	CD
cord-003130-p2h8p5bm	29	47	]	]	-RRB-
cord-003130-p2h8p5bm	29	48	[	[	-LRB-
cord-003130-p2h8p5bm	29	49	27	27	CD
cord-003130-p2h8p5bm	29	50	]	]	-RRB-
cord-003130-p2h8p5bm	29	51	[	[	-LRB-
cord-003130-p2h8p5bm	29	52	28	28	CD
cord-003130-p2h8p5bm	29	53	]	]	-RRB-
cord-003130-p2h8p5bm	29	54	[	[	-LRB-
cord-003130-p2h8p5bm	29	55	29	29	CD
cord-003130-p2h8p5bm	29	56	]	]	-RRB-
cord-003130-p2h8p5bm	29	57	.	.	.
cord-003130-p2h8p5bm	30	1	This	this	DT
cord-003130-p2h8p5bm	30	2	increase	increase	NN
cord-003130-p2h8p5bm	30	3	is	be	VBZ
cord-003130-p2h8p5bm	30	4	thought	think	VBN
cord-003130-p2h8p5bm	30	5	to	to	TO
cord-003130-p2h8p5bm	30	6	be	be	VB
cord-003130-p2h8p5bm	30	7	due	due	JJ
cord-003130-p2h8p5bm	30	8	to	to	IN
cord-003130-p2h8p5bm	30	9	growth	growth	NN
cord-003130-p2h8p5bm	30	10	in	in	IN
cord-003130-p2h8p5bm	30	11	population	population	NN
cord-003130-p2h8p5bm	30	12	and	and	CC
cord-003130-p2h8p5bm	30	13	spread	spread	NN
cord-003130-p2h8p5bm	30	14	of	of	IN
cord-003130-p2h8p5bm	30	15	ticks	tick	NNS
cord-003130-p2h8p5bm	30	16	,	,	,
cord-003130-p2h8p5bm	30	17	which	which	WDT
cord-003130-p2h8p5bm	30	18	is	be	VBZ
cord-003130-p2h8p5bm	30	19	promoted	promote	VBN
cord-003130-p2h8p5bm	30	20	by	by	IN
cord-003130-p2h8p5bm	30	21	factors	factor	NNS
cord-003130-p2h8p5bm	30	22	including	include	VBG
cord-003130-p2h8p5bm	30	23	climate	climate	NN
cord-003130-p2h8p5bm	30	24	change	change	NN
cord-003130-p2h8p5bm	30	25	,	,	,
cord-003130-p2h8p5bm	30	26	social	social	JJ
cord-003130-p2h8p5bm	30	27	and	and	CC
cord-003130-p2h8p5bm	30	28	political	political	JJ
cord-003130-p2h8p5bm	30	29	change	change	NN
cord-003130-p2h8p5bm	30	30	,	,	,
cord-003130-p2h8p5bm	30	31	and	and	CC
cord-003130-p2h8p5bm	30	32	changes	change	NNS
cord-003130-p2h8p5bm	30	33	in	in	IN
cord-003130-p2h8p5bm	30	34	the	the	DT
cord-003130-p2h8p5bm	30	35	land	land	NN
cord-003130-p2h8p5bm	30	36	use	use	NN
cord-003130-p2h8p5bm	30	37	[	[	-LRB-
cord-003130-p2h8p5bm	30	38	30	30	CD
cord-003130-p2h8p5bm	30	39	,	,	,
cord-003130-p2h8p5bm	30	40	31	31	CD
cord-003130-p2h8p5bm	30	41	]	]	-RRB-
cord-003130-p2h8p5bm	30	42	.	.	.
cord-003130-p2h8p5bm	31	1	The	the	DT
cord-003130-p2h8p5bm	31	2	increased	increase	VBN
cord-003130-p2h8p5bm	31	3	expansion	expansion	NN
cord-003130-p2h8p5bm	31	4	in	in	IN
cord-003130-p2h8p5bm	31	5	Europe	Europe	NNP
cord-003130-p2h8p5bm	31	6	also	also	RB
cord-003130-p2h8p5bm	31	7	poses	pose	VBZ
cord-003130-p2h8p5bm	31	8	an	an	DT
cord-003130-p2h8p5bm	31	9	increased	increase	VBN
cord-003130-p2h8p5bm	31	10	risk	risk	NN
cord-003130-p2h8p5bm	31	11	for	for	IN
cord-003130-p2h8p5bm	31	12	the	the	DT
cord-003130-p2h8p5bm	31	13	population	population	NN
cord-003130-p2h8p5bm	31	14	engaged	engage	VBN
cord-003130-p2h8p5bm	31	15	in	in	IN
cord-003130-p2h8p5bm	31	16	outdoor	outdoor	JJ
cord-003130-p2h8p5bm	31	17	activities	activity	NNS
cord-003130-p2h8p5bm	31	18	.	.	.
cord-003130-p2h8p5bm	32	1	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	32	2	is	be	VBZ
cord-003130-p2h8p5bm	32	3	a	a	DT
cord-003130-p2h8p5bm	32	4	zoonotic	zoonotic	JJ
cord-003130-p2h8p5bm	32	5	disease	disease	NN
cord-003130-p2h8p5bm	32	6	and	and	CC
cord-003130-p2h8p5bm	32	7	the	the	DT
cord-003130-p2h8p5bm	32	8	natural	natural	JJ
cord-003130-p2h8p5bm	32	9	cycle	cycle	NN
cord-003130-p2h8p5bm	32	10	of	of	IN
cord-003130-p2h8p5bm	32	11	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	32	12	is	be	VBZ
cord-003130-p2h8p5bm	32	13	dependent	dependent	JJ
cord-003130-p2h8p5bm	32	14	and	and	CC
cord-003130-p2h8p5bm	32	15	maintained	maintain	VBN
cord-003130-p2h8p5bm	32	16	in	in	IN
cord-003130-p2h8p5bm	32	17	a	a	DT
cord-003130-p2h8p5bm	32	18	complex	complex	JJ
cord-003130-p2h8p5bm	32	19	cycle	cycle	NN
cord-003130-p2h8p5bm	32	20	involving	involve	VBG
cord-003130-p2h8p5bm	32	21	ticks	tick	NNS
cord-003130-p2h8p5bm	32	22	as	as	IN
cord-003130-p2h8p5bm	32	23	the	the	DT
cord-003130-p2h8p5bm	32	24	vector	vector	NN
cord-003130-p2h8p5bm	32	25	and	and	CC
cord-003130-p2h8p5bm	32	26	reservoir	reservoir	NN
cord-003130-p2h8p5bm	32	27	of	of	IN
cord-003130-p2h8p5bm	32	28	the	the	DT
cord-003130-p2h8p5bm	32	29	virus	virus	NN
cord-003130-p2h8p5bm	32	30	and	and	CC
cord-003130-p2h8p5bm	32	31	small	small	JJ
cord-003130-p2h8p5bm	32	32	rodents	rodent	NNS
cord-003130-p2h8p5bm	32	33	as	as	IN
cord-003130-p2h8p5bm	32	34	hosts	host	NNS
cord-003130-p2h8p5bm	32	35	for	for	IN
cord-003130-p2h8p5bm	32	36	ticks	tick	NNS
cord-003130-p2h8p5bm	32	37	[	[	-LRB-
cord-003130-p2h8p5bm	32	38	32	32	CD
cord-003130-p2h8p5bm	32	39	]	]	-RRB-
cord-003130-p2h8p5bm	32	40	.	.	.
cord-003130-p2h8p5bm	33	1	Humans	human	NNS
cord-003130-p2h8p5bm	33	2	are	be	VBP
cord-003130-p2h8p5bm	33	3	not	not	RB
cord-003130-p2h8p5bm	33	4	part	part	NN
cord-003130-p2h8p5bm	33	5	of	of	IN
cord-003130-p2h8p5bm	33	6	the	the	DT
cord-003130-p2h8p5bm	33	7	natural	natural	JJ
cord-003130-p2h8p5bm	33	8	transmission	transmission	NN
cord-003130-p2h8p5bm	33	9	cycle	cycle	NN
cord-003130-p2h8p5bm	33	10	of	of	IN
cord-003130-p2h8p5bm	33	11	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	33	12	and	and	CC
cord-003130-p2h8p5bm	33	13	are	be	VBP
cord-003130-p2h8p5bm	33	14	the	the	DT
cord-003130-p2h8p5bm	33	15	incidental	incidental	JJ
cord-003130-p2h8p5bm	33	16	host	host	NN
cord-003130-p2h8p5bm	33	17	when	when	WRB
cord-003130-p2h8p5bm	33	18	infected	infect	VBN
cord-003130-p2h8p5bm	33	19	by	by	IN
cord-003130-p2h8p5bm	33	20	a	a	DT
cord-003130-p2h8p5bm	33	21	bite	bite	NN
cord-003130-p2h8p5bm	33	22	from	from	IN
cord-003130-p2h8p5bm	33	23	an	an	DT
cord-003130-p2h8p5bm	33	24	infected	infected	JJ
cord-003130-p2h8p5bm	33	25	tick	tick	NN
cord-003130-p2h8p5bm	33	26	[	[	-LRB-
cord-003130-p2h8p5bm	33	27	33	33	CD
cord-003130-p2h8p5bm	33	28	]	]	-RRB-
cord-003130-p2h8p5bm	33	29	.	.	.
cord-003130-p2h8p5bm	34	1	Transmission	transmission	NN
cord-003130-p2h8p5bm	34	2	through	through	IN
cord-003130-p2h8p5bm	34	3	consumption	consumption	NN
cord-003130-p2h8p5bm	34	4	of	of	IN
cord-003130-p2h8p5bm	34	5	unpasteurized	unpasteurized	JJ
cord-003130-p2h8p5bm	34	6	milk	milk	NN
cord-003130-p2h8p5bm	34	7	has	have	VBZ
cord-003130-p2h8p5bm	34	8	also	also	RB
cord-003130-p2h8p5bm	34	9	been	be	VBN
cord-003130-p2h8p5bm	34	10	reported	report	VBN
cord-003130-p2h8p5bm	34	11	for	for	IN
cord-003130-p2h8p5bm	34	12	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	34	13	[	[	-LRB-
cord-003130-p2h8p5bm	34	14	34	34	CD
cord-003130-p2h8p5bm	34	15	,	,	,
cord-003130-p2h8p5bm	34	16	35	35	CD
cord-003130-p2h8p5bm	34	17	]	]	-RRB-
cord-003130-p2h8p5bm	34	18	,	,	,
cord-003130-p2h8p5bm	34	19	as	as	RB
cord-003130-p2h8p5bm	34	20	well	well	RB
cord-003130-p2h8p5bm	34	21	as	as	IN
cord-003130-p2h8p5bm	34	22	transmission	transmission	NN
cord-003130-p2h8p5bm	34	23	via	via	IN
cord-003130-p2h8p5bm	34	24	solid	solid	JJ
cord-003130-p2h8p5bm	34	25	organ	organ	NN
cord-003130-p2h8p5bm	34	26	transplant	transplant	NN
cord-003130-p2h8p5bm	34	27	[	[	-LRB-
cord-003130-p2h8p5bm	34	28	36	36	CD
cord-003130-p2h8p5bm	34	29	]	]	-RRB-
cord-003130-p2h8p5bm	34	30	.	.	.
cord-003130-p2h8p5bm	35	1	During	during	IN
cord-003130-p2h8p5bm	35	2	the	the	DT
cord-003130-p2h8p5bm	35	3	tick	tick	NN
cord-003130-p2h8p5bm	35	4	bite	bite	NN
cord-003130-p2h8p5bm	35	5	,	,	,
cord-003130-p2h8p5bm	35	6	the	the	DT
cord-003130-p2h8p5bm	35	7	virus	virus	NN
cord-003130-p2h8p5bm	35	8	is	be	VBZ
cord-003130-p2h8p5bm	35	9	inoculated	inoculate	VBN
cord-003130-p2h8p5bm	35	10	into	into	IN
cord-003130-p2h8p5bm	35	11	the	the	DT
cord-003130-p2h8p5bm	35	12	skin	skin	NN
cord-003130-p2h8p5bm	35	13	of	of	IN
cord-003130-p2h8p5bm	35	14	the	the	DT
cord-003130-p2h8p5bm	35	15	vertebrate	vertebrate	JJ
cord-003130-p2h8p5bm	35	16	host	host	NN
cord-003130-p2h8p5bm	35	17	.	.	.
cord-003130-p2h8p5bm	36	1	The	the	DT
cord-003130-p2h8p5bm	36	2	initial	initial	JJ
cord-003130-p2h8p5bm	36	3	replication	replication	NN
cord-003130-p2h8p5bm	36	4	is	be	VBZ
cord-003130-p2h8p5bm	36	5	believed	believe	VBN
cord-003130-p2h8p5bm	36	6	to	to	TO
cord-003130-p2h8p5bm	36	7	occur	occur	VB
cord-003130-p2h8p5bm	36	8	locally	locally	RB
cord-003130-p2h8p5bm	36	9	in	in	IN
cord-003130-p2h8p5bm	36	10	the	the	DT
cord-003130-p2h8p5bm	36	11	dendritic	dendritic	JJ
cord-003130-p2h8p5bm	36	12	cells	cell	NNS
cord-003130-p2h8p5bm	36	13	.	.	.
cord-003130-p2h8p5bm	37	1	This	this	DT
cord-003130-p2h8p5bm	37	2	is	be	VBZ
cord-003130-p2h8p5bm	37	3	followed	follow	VBN
cord-003130-p2h8p5bm	37	4	by	by	IN
cord-003130-p2h8p5bm	37	5	infection	infection	NN
cord-003130-p2h8p5bm	37	6	of	of	IN
cord-003130-p2h8p5bm	37	7	the	the	DT
cord-003130-p2h8p5bm	37	8	draining	drain	VBG
cord-003130-p2h8p5bm	37	9	lymph	lymph	NN
cord-003130-p2h8p5bm	37	10	nodes	node	NNS
cord-003130-p2h8p5bm	37	11	,	,	,
cord-003130-p2h8p5bm	37	12	resulting	result	VBG
cord-003130-p2h8p5bm	37	13	in	in	IN
cord-003130-p2h8p5bm	37	14	the	the	DT
cord-003130-p2h8p5bm	37	15	primary	primary	JJ
cord-003130-p2h8p5bm	37	16	viremia	viremia	NN
cord-003130-p2h8p5bm	37	17	and	and	CC
cord-003130-p2h8p5bm	37	18	subsequent	subsequent	JJ
cord-003130-p2h8p5bm	37	19	infection	infection	NN
cord-003130-p2h8p5bm	37	20	of	of	IN
cord-003130-p2h8p5bm	37	21	the	the	DT
cord-003130-p2h8p5bm	37	22	peripheral	peripheral	JJ
cord-003130-p2h8p5bm	37	23	tissues	tissue	NNS
cord-003130-p2h8p5bm	37	24	,	,	,
cord-003130-p2h8p5bm	37	25	where	where	WRB
cord-003130-p2h8p5bm	37	26	further	further	JJ
cord-003130-p2h8p5bm	37	27	replication	replication	NN
cord-003130-p2h8p5bm	37	28	maintains	maintain	VBZ
cord-003130-p2h8p5bm	37	29	the	the	DT
cord-003130-p2h8p5bm	37	30	viremia	viremia	NN
cord-003130-p2h8p5bm	37	31	for	for	IN
cord-003130-p2h8p5bm	37	32	several	several	JJ
cord-003130-p2h8p5bm	37	33	days	day	NNS
cord-003130-p2h8p5bm	37	34	[	[	-LRB-
cord-003130-p2h8p5bm	37	35	37	37	CD
cord-003130-p2h8p5bm	37	36	]	]	-RRB-
cord-003130-p2h8p5bm	38	1	[	[	-LRB-
cord-003130-p2h8p5bm	38	2	38	38	CD
cord-003130-p2h8p5bm	38	3	]	]	-RRB-
cord-003130-p2h8p5bm	39	1	[	[	-LRB-
cord-003130-p2h8p5bm	39	2	39	39	CD
cord-003130-p2h8p5bm	39	3	]	]	-RRB-
cord-003130-p2h8p5bm	39	4	[	[	-LRB-
cord-003130-p2h8p5bm	39	5	40	40	CD
cord-003130-p2h8p5bm	39	6	]	]	-RRB-
cord-003130-p2h8p5bm	39	7	.	.	.
cord-003130-p2h8p5bm	40	1	The	the	DT
cord-003130-p2h8p5bm	40	2	disease	disease	NN
cord-003130-p2h8p5bm	40	3	course	course	NN
cord-003130-p2h8p5bm	40	4	of	of	IN
cord-003130-p2h8p5bm	40	5	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	40	6	is	be	VBZ
cord-003130-p2h8p5bm	40	7	biphasic	biphasic	JJ
cord-003130-p2h8p5bm	40	8	;	;	:
cord-003130-p2h8p5bm	40	9	the	the	DT
cord-003130-p2h8p5bm	40	10	initial	initial	JJ
cord-003130-p2h8p5bm	40	11	phase	phase	NN
cord-003130-p2h8p5bm	40	12	is	be	VBZ
cord-003130-p2h8p5bm	40	13	characterized	characterize	VBN
cord-003130-p2h8p5bm	40	14	by	by	IN
cord-003130-p2h8p5bm	40	15	flu	flu	NN
cord-003130-p2h8p5bm	40	16	-	-	HYPH
cord-003130-p2h8p5bm	40	17	like	like	JJ
cord-003130-p2h8p5bm	40	18	symptoms	symptom	NNS
cord-003130-p2h8p5bm	40	19	and	and	CC
cord-003130-p2h8p5bm	40	20	is	be	VBZ
cord-003130-p2h8p5bm	40	21	followed	follow	VBN
cord-003130-p2h8p5bm	40	22	by	by	IN
cord-003130-p2h8p5bm	40	23	a	a	DT
cord-003130-p2h8p5bm	40	24	second	second	JJ
cord-003130-p2h8p5bm	40	25	phase	phase	NN
cord-003130-p2h8p5bm	40	26	involving	involve	VBG
cord-003130-p2h8p5bm	40	27	CNS	CNS	NNP
cord-003130-p2h8p5bm	40	28	infection	infection	NN
cord-003130-p2h8p5bm	40	29	,	,	,
cord-003130-p2h8p5bm	40	30	with	with	IN
cord-003130-p2h8p5bm	40	31	meningitis	meningitis	NN
cord-003130-p2h8p5bm	40	32	,	,	,
cord-003130-p2h8p5bm	40	33	encephalitis	encephalitis	RB
cord-003130-p2h8p5bm	40	34	,	,	,
cord-003130-p2h8p5bm	40	35	or	or	CC
cord-003130-p2h8p5bm	40	36	meningoencephalitis	meningoencephalitis	NNP
cord-003130-p2h8p5bm	40	37	[	[	-LRB-
cord-003130-p2h8p5bm	40	38	41	41	CD
cord-003130-p2h8p5bm	40	39	]	]	-RRB-
cord-003130-p2h8p5bm	40	40	[	[	-LRB-
cord-003130-p2h8p5bm	40	41	42	42	CD
cord-003130-p2h8p5bm	40	42	]	]	-RRB-
cord-003130-p2h8p5bm	40	43	[	[	-LRB-
cord-003130-p2h8p5bm	40	44	43	43	CD
cord-003130-p2h8p5bm	40	45	]	]	-RRB-
cord-003130-p2h8p5bm	40	46	.	.	.
cord-003130-p2h8p5bm	41	1	The	the	DT
cord-003130-p2h8p5bm	41	2	mortality	mortality	NN
cord-003130-p2h8p5bm	41	3	rate	rate	NN
cord-003130-p2h8p5bm	41	4	of	of	IN
cord-003130-p2h8p5bm	41	5	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	41	6	varies	vary	VBZ
cord-003130-p2h8p5bm	41	7	from	from	IN
cord-003130-p2h8p5bm	41	8	1	1	CD
cord-003130-p2h8p5bm	41	9	to	to	TO
cord-003130-p2h8p5bm	41	10	20	20	CD
cord-003130-p2h8p5bm	41	11	%	%	NN
cord-003130-p2h8p5bm	41	12	depending	depend	VBG
cord-003130-p2h8p5bm	41	13	on	on	IN
cord-003130-p2h8p5bm	41	14	the	the	DT
cord-003130-p2h8p5bm	41	15	subtype	subtype	NN
cord-003130-p2h8p5bm	41	16	,	,	,
cord-003130-p2h8p5bm	41	17	in	in	IN
cord-003130-p2h8p5bm	41	18	which	which	WDT
cord-003130-p2h8p5bm	41	19	the	the	DT
cord-003130-p2h8p5bm	41	20	European	european	JJ
cord-003130-p2h8p5bm	41	21	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	41	22	subtype	subtype	NN
cord-003130-p2h8p5bm	41	23	has	have	VBZ
cord-003130-p2h8p5bm	41	24	shown	show	VBN
cord-003130-p2h8p5bm	41	25	lower	low	JJR
cord-003130-p2h8p5bm	41	26	mortality	mortality	NN
cord-003130-p2h8p5bm	41	27	rates	rate	NNS
cord-003130-p2h8p5bm	41	28	compared	compare	VBN
cord-003130-p2h8p5bm	41	29	to	to	IN
cord-003130-p2h8p5bm	41	30	the	the	DT
cord-003130-p2h8p5bm	41	31	Siberian	Siberian	NNP
cord-003130-p2h8p5bm	41	32	and	and	CC
cord-003130-p2h8p5bm	41	33	Far	far	JJ
cord-003130-p2h8p5bm	41	34	Eastern	Eastern	NNP
cord-003130-p2h8p5bm	41	35	[	[	-LRB-
cord-003130-p2h8p5bm	41	36	23	23	CD
cord-003130-p2h8p5bm	41	37	,	,	,
cord-003130-p2h8p5bm	41	38	40	40	CD
cord-003130-p2h8p5bm	41	39	,	,	,
cord-003130-p2h8p5bm	41	40	44	44	CD
cord-003130-p2h8p5bm	41	41	]	]	-RRB-
cord-003130-p2h8p5bm	41	42	.	.	.
cord-003130-p2h8p5bm	42	1	Among	among	IN
cord-003130-p2h8p5bm	42	2	the	the	DT
cord-003130-p2h8p5bm	42	3	patients	patient	NNS
cord-003130-p2h8p5bm	42	4	that	that	WDT
cord-003130-p2h8p5bm	42	5	experience	experience	VBP
cord-003130-p2h8p5bm	42	6	neuroinvasive	neuroinvasive	JJ
cord-003130-p2h8p5bm	42	7	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	42	8	infection	infection	NN
cord-003130-p2h8p5bm	42	9	,	,	,
cord-003130-p2h8p5bm	42	10	approximately	approximately	RB
cord-003130-p2h8p5bm	42	11	25	25	CD
cord-003130-p2h8p5bm	42	12	-	-	SYM
cord-003130-p2h8p5bm	42	13	40	40	CD
cord-003130-p2h8p5bm	42	14	%	%	NN
cord-003130-p2h8p5bm	42	15	of	of	IN
cord-003130-p2h8p5bm	42	16	the	the	DT
cord-003130-p2h8p5bm	42	17	survivors	survivor	NNS
cord-003130-p2h8p5bm	42	18	suffer	suffer	VBP
cord-003130-p2h8p5bm	42	19	from	from	IN
cord-003130-p2h8p5bm	42	20	long	long	RB
cord-003130-p2h8p5bm	42	21	lasting	last	VBG
cord-003130-p2h8p5bm	42	22	neurological	neurological	JJ
cord-003130-p2h8p5bm	42	23	sequelae	sequela	NNS
cord-003130-p2h8p5bm	42	24	[	[	-LRB-
cord-003130-p2h8p5bm	42	25	45	45	CD
cord-003130-p2h8p5bm	42	26	,	,	,
cord-003130-p2h8p5bm	42	27	46	46	CD
cord-003130-p2h8p5bm	42	28	]	]	-RRB-
cord-003130-p2h8p5bm	42	29	.	.	.
cord-003130-p2h8p5bm	43	1	No	no	DT
cord-003130-p2h8p5bm	43	2	antivirals	antiviral	NNS
cord-003130-p2h8p5bm	43	3	are	be	VBP
cord-003130-p2h8p5bm	43	4	available	available	JJ
cord-003130-p2h8p5bm	43	5	for	for	IN
cord-003130-p2h8p5bm	43	6	treatment	treatment	NN
cord-003130-p2h8p5bm	43	7	of	of	IN
cord-003130-p2h8p5bm	43	8	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	43	9	infection	infection	NN
cord-003130-p2h8p5bm	43	10	but	but	CC
cord-003130-p2h8p5bm	43	11	there	there	EX
cord-003130-p2h8p5bm	43	12	is	be	VBZ
cord-003130-p2h8p5bm	43	13	an	an	DT
cord-003130-p2h8p5bm	43	14	effective	effective	JJ
cord-003130-p2h8p5bm	43	15	vaccine	vaccine	NN
cord-003130-p2h8p5bm	43	16	[	[	-LRB-
cord-003130-p2h8p5bm	43	17	25	25	CD
cord-003130-p2h8p5bm	43	18	,	,	,
cord-003130-p2h8p5bm	43	19	47	47	CD
cord-003130-p2h8p5bm	43	20	]	]	-RRB-
cord-003130-p2h8p5bm	43	21	.	.	.
cord-003130-p2h8p5bm	44	1	LGTV	LGTV	NNP
cord-003130-p2h8p5bm	44	2	,	,	,
cord-003130-p2h8p5bm	44	3	which	which	WDT
cord-003130-p2h8p5bm	44	4	is	be	VBZ
cord-003130-p2h8p5bm	44	5	closely	closely	RB
cord-003130-p2h8p5bm	44	6	related	relate	VBN
cord-003130-p2h8p5bm	44	7	to	to	IN
cord-003130-p2h8p5bm	44	8	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	44	9	,	,	,
cord-003130-p2h8p5bm	44	10	is	be	VBZ
cord-003130-p2h8p5bm	44	11	found	find	VBN
cord-003130-p2h8p5bm	44	12	in	in	IN
cord-003130-p2h8p5bm	44	13	south	south	NNP
cord-003130-p2h8p5bm	44	14	east	east	NN
cord-003130-p2h8p5bm	44	15	Asia	Asia	NNP
cord-003130-p2h8p5bm	44	16	and	and	CC
cord-003130-p2h8p5bm	44	17	Russia	Russia	NNP
cord-003130-p2h8p5bm	44	18	[	[	-LRB-
cord-003130-p2h8p5bm	44	19	17	17	CD
cord-003130-p2h8p5bm	44	20	]	]	-RRB-
cord-003130-p2h8p5bm	44	21	.	.	.
cord-003130-p2h8p5bm	45	1	LGTV	LGTV	NNP
cord-003130-p2h8p5bm	45	2	has	have	VBZ
cord-003130-p2h8p5bm	45	3	not	not	RB
cord-003130-p2h8p5bm	45	4	been	be	VBN
cord-003130-p2h8p5bm	45	5	associated	associate	VBN
cord-003130-p2h8p5bm	45	6	with	with	IN
cord-003130-p2h8p5bm	45	7	human	human	JJ
cord-003130-p2h8p5bm	45	8	disease	disease	NN
cord-003130-p2h8p5bm	45	9	under	under	IN
cord-003130-p2h8p5bm	45	10	natural	natural	JJ
cord-003130-p2h8p5bm	45	11	infections	infection	NNS
cord-003130-p2h8p5bm	45	12	although	although	IN
cord-003130-p2h8p5bm	45	13	it	-PRON-	PRP
cord-003130-p2h8p5bm	45	14	shares	share	VBZ
cord-003130-p2h8p5bm	45	15	84	84	CD
cord-003130-p2h8p5bm	45	16	%	%	NN
cord-003130-p2h8p5bm	45	17	sequence	sequence	NN
cord-003130-p2h8p5bm	45	18	identity	identity	NN
cord-003130-p2h8p5bm	45	19	with	with	IN
cord-003130-p2h8p5bm	45	20	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	45	21	[	[	-LRB-
cord-003130-p2h8p5bm	45	22	17	17	CD
cord-003130-p2h8p5bm	45	23	]	]	-RRB-
cord-003130-p2h8p5bm	45	24	.	.	.
cord-003130-p2h8p5bm	46	1	Because	because	IN
cord-003130-p2h8p5bm	46	2	of	of	IN
cord-003130-p2h8p5bm	46	3	its	-PRON-	PRP$
cord-003130-p2h8p5bm	46	4	avirulence	avirulence	NN
cord-003130-p2h8p5bm	46	5	in	in	IN
cord-003130-p2h8p5bm	46	6	humans	human	NNS
cord-003130-p2h8p5bm	46	7	and	and	CC
cord-003130-p2h8p5bm	46	8	close	close	JJ
cord-003130-p2h8p5bm	46	9	similarity	similarity	NN
cord-003130-p2h8p5bm	46	10	to	to	IN
cord-003130-p2h8p5bm	46	11	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	46	12	,	,	,
cord-003130-p2h8p5bm	46	13	LGTV	LGTV	NNP
cord-003130-p2h8p5bm	46	14	is	be	VBZ
cord-003130-p2h8p5bm	46	15	often	often	RB
cord-003130-p2h8p5bm	46	16	used	use	VBN
cord-003130-p2h8p5bm	46	17	as	as	IN
cord-003130-p2h8p5bm	46	18	a	a	DT
cord-003130-p2h8p5bm	46	19	model	model	NN
cord-003130-p2h8p5bm	46	20	virus	virus	NN
cord-003130-p2h8p5bm	46	21	for	for	IN
cord-003130-p2h8p5bm	46	22	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	46	23	under	under	IN
cord-003130-p2h8p5bm	46	24	biosafety	biosafety	NN
cord-003130-p2h8p5bm	46	25	level-2	level-2	NN
cord-003130-p2h8p5bm	46	26	conditions	condition	NNS
cord-003130-p2h8p5bm	46	27	.	.	.
cord-003130-p2h8p5bm	47	1	POWV	POWV	NNP
cord-003130-p2h8p5bm	47	2	is	be	VBZ
cord-003130-p2h8p5bm	47	3	found	find	VBN
cord-003130-p2h8p5bm	47	4	in	in	IN
cord-003130-p2h8p5bm	47	5	Russia	Russia	NNP
cord-003130-p2h8p5bm	47	6	and	and	CC
cord-003130-p2h8p5bm	47	7	North	North	NNP
cord-003130-p2h8p5bm	47	8	America	America	NNP
cord-003130-p2h8p5bm	47	9	,	,	,
cord-003130-p2h8p5bm	47	10	and	and	CC
cord-003130-p2h8p5bm	47	11	is	be	VBZ
cord-003130-p2h8p5bm	47	12	the	the	DT
cord-003130-p2h8p5bm	47	13	only	only	JJ
cord-003130-p2h8p5bm	47	14	TBFV	tbfv	NN
cord-003130-p2h8p5bm	47	15	present	present	JJ
cord-003130-p2h8p5bm	47	16	in	in	IN
cord-003130-p2h8p5bm	47	17	America	America	NNP
cord-003130-p2h8p5bm	47	18	(	(	-LRB-
cord-003130-p2h8p5bm	47	19	Figure	figure	NN
cord-003130-p2h8p5bm	47	20	1	1	CD
cord-003130-p2h8p5bm	47	21	)	)	-RRB-
cord-003130-p2h8p5bm	47	22	[	[	-LRB-
cord-003130-p2h8p5bm	47	23	48	48	CD
cord-003130-p2h8p5bm	47	24	]	]	-RRB-
cord-003130-p2h8p5bm	47	25	.	.	.
cord-003130-p2h8p5bm	48	1	It	-PRON-	PRP
cord-003130-p2h8p5bm	48	2	is	be	VBZ
cord-003130-p2h8p5bm	48	3	transmitted	transmit	VBN
cord-003130-p2h8p5bm	48	4	by	by	IN
cord-003130-p2h8p5bm	48	5	Ixodes	Ixodes	NNP
cord-003130-p2h8p5bm	48	6	scapularis	scapularis	NN
cord-003130-p2h8p5bm	48	7	,	,	,
cord-003130-p2h8p5bm	48	8	Ixodes	Ixodes	NNP
cord-003130-p2h8p5bm	48	9	cookei	cookei	NNP
cord-003130-p2h8p5bm	48	10	,	,	,
cord-003130-p2h8p5bm	48	11	and	and	CC
cord-003130-p2h8p5bm	48	12	several	several	JJ
cord-003130-p2h8p5bm	48	13	other	other	JJ
cord-003130-p2h8p5bm	48	14	Ixodes	Ixodes	NNP
cord-003130-p2h8p5bm	48	15	tick	tick	VB
cord-003130-p2h8p5bm	48	16	species	specie	NNS
cord-003130-p2h8p5bm	48	17	,	,	,
cord-003130-p2h8p5bm	48	18	to	to	IN
cord-003130-p2h8p5bm	48	19	small	small	JJ
cord-003130-p2h8p5bm	48	20	and	and	CC
cord-003130-p2h8p5bm	48	21	medium	medium	JJ
cord-003130-p2h8p5bm	48	22	size	size	NN
cord-003130-p2h8p5bm	48	23	mammals	mammal	NNS
cord-003130-p2h8p5bm	48	24	,	,	,
cord-003130-p2h8p5bm	48	25	whereas	whereas	IN
cord-003130-p2h8p5bm	48	26	humans	human	NNS
cord-003130-p2h8p5bm	48	27	are	be	VBP
cord-003130-p2h8p5bm	48	28	accidental	accidental	JJ
cord-003130-p2h8p5bm	48	29	dead	dead	JJ
cord-003130-p2h8p5bm	48	30	-	-	HYPH
cord-003130-p2h8p5bm	48	31	end	end	NN
cord-003130-p2h8p5bm	48	32	hosts	host	NNS
cord-003130-p2h8p5bm	48	33	.	.	.
cord-003130-p2h8p5bm	49	1	Milk	milk	NN
cord-003130-p2h8p5bm	49	2	-	-	HYPH
cord-003130-p2h8p5bm	49	3	borne	bear	VBN
cord-003130-p2h8p5bm	49	4	POWV	POWV	NNP
cord-003130-p2h8p5bm	49	5	transmission	transmission	NN
cord-003130-p2h8p5bm	49	6	might	may	MD
cord-003130-p2h8p5bm	49	7	also	also	RB
cord-003130-p2h8p5bm	49	8	be	be	VB
cord-003130-p2h8p5bm	49	9	possible	possible	JJ
cord-003130-p2h8p5bm	49	10	since	since	IN
cord-003130-p2h8p5bm	49	11	POWV	POWV	NNP
cord-003130-p2h8p5bm	49	12	virus	virus	NN
cord-003130-p2h8p5bm	49	13	has	have	VBZ
cord-003130-p2h8p5bm	49	14	been	be	VBN
cord-003130-p2h8p5bm	49	15	found	find	VBN
cord-003130-p2h8p5bm	49	16	to	to	TO
cord-003130-p2h8p5bm	49	17	be	be	VB
cord-003130-p2h8p5bm	49	18	secreted	secrete	VBN
cord-003130-p2h8p5bm	49	19	in	in	IN
cord-003130-p2h8p5bm	49	20	milk	milk	NN
cord-003130-p2h8p5bm	49	21	under	under	IN
cord-003130-p2h8p5bm	49	22	experimental	experimental	JJ
cord-003130-p2h8p5bm	49	23	settings	setting	NNS
cord-003130-p2h8p5bm	49	24	[	[	-LRB-
cord-003130-p2h8p5bm	49	25	49	49	CD
cord-003130-p2h8p5bm	49	26	]	]	-RRB-
cord-003130-p2h8p5bm	49	27	.	.	.
cord-003130-p2h8p5bm	50	1	Although	although	IN
cord-003130-p2h8p5bm	50	2	not	not	RB
cord-003130-p2h8p5bm	50	3	much	much	JJ
cord-003130-p2h8p5bm	50	4	is	be	VBZ
cord-003130-p2h8p5bm	50	5	known	know	VBN
cord-003130-p2h8p5bm	50	6	about	about	IN
cord-003130-p2h8p5bm	50	7	POWV	POWV	NNP
cord-003130-p2h8p5bm	50	8	pathogenesis	pathogenesis	NN
cord-003130-p2h8p5bm	50	9	,	,	,
cord-003130-p2h8p5bm	50	10	recent	recent	JJ
cord-003130-p2h8p5bm	50	11	studies	study	NNS
cord-003130-p2h8p5bm	50	12	in	in	IN
cord-003130-p2h8p5bm	50	13	mice	mouse	NNS
cord-003130-p2h8p5bm	50	14	have	have	VBP
cord-003130-p2h8p5bm	50	15	found	find	VBN
cord-003130-p2h8p5bm	50	16	that	that	WDT
cord-003130-p2h8p5bm	50	17	tick	tick	NN
cord-003130-p2h8p5bm	50	18	saliva	saliva	NN
cord-003130-p2h8p5bm	50	19	was	be	VBD
cord-003130-p2h8p5bm	50	20	important	important	JJ
cord-003130-p2h8p5bm	50	21	to	to	TO
cord-003130-p2h8p5bm	50	22	enhance	enhance	VB
cord-003130-p2h8p5bm	50	23	POWV	POWV	NNP
cord-003130-p2h8p5bm	50	24	transmission	transmission	NN
cord-003130-p2h8p5bm	50	25	and	and	CC
cord-003130-p2h8p5bm	50	26	the	the	DT
cord-003130-p2h8p5bm	50	27	outcome	outcome	NN
cord-003130-p2h8p5bm	50	28	of	of	IN
cord-003130-p2h8p5bm	50	29	disease	disease	NN
cord-003130-p2h8p5bm	50	30	[	[	-LRB-
cord-003130-p2h8p5bm	50	31	50	50	CD
cord-003130-p2h8p5bm	50	32	]	]	-RRB-
cord-003130-p2h8p5bm	50	33	.	.	.
cord-003130-p2h8p5bm	51	1	Furthermore	furthermore	RB
cord-003130-p2h8p5bm	51	2	,	,	,
cord-003130-p2h8p5bm	51	3	it	-PRON-	PRP
cord-003130-p2h8p5bm	51	4	has	have	VBZ
cord-003130-p2h8p5bm	51	5	been	be	VBN
cord-003130-p2h8p5bm	51	6	demonstrated	demonstrate	VBN
cord-003130-p2h8p5bm	51	7	that	that	IN
cord-003130-p2h8p5bm	51	8	POWV	POWV	NNP
cord-003130-p2h8p5bm	51	9	infects	infect	VBZ
cord-003130-p2h8p5bm	51	10	macrophages	macrophage	NNS
cord-003130-p2h8p5bm	51	11	and	and	CC
cord-003130-p2h8p5bm	51	12	fibroblasts	fibroblast	NNS
cord-003130-p2h8p5bm	51	13	in	in	IN
cord-003130-p2h8p5bm	51	14	the	the	DT
cord-003130-p2h8p5bm	51	15	skin	skin	NN
cord-003130-p2h8p5bm	51	16	,	,	,
cord-003130-p2h8p5bm	51	17	shortly	shortly	RB
cord-003130-p2h8p5bm	51	18	after	after	IN
cord-003130-p2h8p5bm	51	19	the	the	DT
cord-003130-p2h8p5bm	51	20	tick	tick	NN
cord-003130-p2h8p5bm	51	21	bite	bite	NN
cord-003130-p2h8p5bm	51	22	,	,	,
cord-003130-p2h8p5bm	51	23	also	also	RB
cord-003130-p2h8p5bm	51	24	,	,	,
cord-003130-p2h8p5bm	51	25	other	other	JJ
cord-003130-p2h8p5bm	51	26	unidentified	unidentified	JJ
cord-003130-p2h8p5bm	51	27	cells	cell	NNS
cord-003130-p2h8p5bm	51	28	were	be	VBD
cord-003130-p2h8p5bm	51	29	shown	show	VBN
cord-003130-p2h8p5bm	51	30	to	to	TO
cord-003130-p2h8p5bm	51	31	be	be	VB
cord-003130-p2h8p5bm	51	32	infected	infect	VBN
cord-003130-p2h8p5bm	51	33	[	[	-LRB-
cord-003130-p2h8p5bm	51	34	51	51	CD
cord-003130-p2h8p5bm	51	35	]	]	-RRB-
cord-003130-p2h8p5bm	51	36	.	.	.
cord-003130-p2h8p5bm	52	1	Interestingly	interestingly	RB
cord-003130-p2h8p5bm	52	2	,	,	,
cord-003130-p2h8p5bm	52	3	macrophages	macrophage	NNS
cord-003130-p2h8p5bm	52	4	were	be	VBD
cord-003130-p2h8p5bm	52	5	found	find	VBN
cord-003130-p2h8p5bm	52	6	to	to	TO
cord-003130-p2h8p5bm	52	7	be	be	VB
cord-003130-p2h8p5bm	52	8	the	the	DT
cord-003130-p2h8p5bm	52	9	primary	primary	JJ
cord-003130-p2h8p5bm	52	10	target	target	NN
cord-003130-p2h8p5bm	52	11	for	for	IN
cord-003130-p2h8p5bm	52	12	POWV	POWV	NNP
cord-003130-p2h8p5bm	52	13	in	in	IN
cord-003130-p2h8p5bm	52	14	the	the	DT
cord-003130-p2h8p5bm	52	15	spleen	spleen	NN
cord-003130-p2h8p5bm	52	16	[	[	-LRB-
cord-003130-p2h8p5bm	52	17	52	52	CD
cord-003130-p2h8p5bm	52	18	]	]	-RRB-
cord-003130-p2h8p5bm	52	19	,	,	,
cord-003130-p2h8p5bm	52	20	and	and	CC
cord-003130-p2h8p5bm	52	21	in	in	IN
cord-003130-p2h8p5bm	52	22	the	the	DT
cord-003130-p2h8p5bm	52	23	CNS	CNS	NNP
cord-003130-p2h8p5bm	52	24	,	,	,
cord-003130-p2h8p5bm	52	25	which	which	WDT
cord-003130-p2h8p5bm	52	26	is	be	VBZ
cord-003130-p2h8p5bm	52	27	the	the	DT
cord-003130-p2h8p5bm	52	28	main	main	JJ
cord-003130-p2h8p5bm	52	29	target	target	NN
cord-003130-p2h8p5bm	52	30	site	site	NN
cord-003130-p2h8p5bm	52	31	for	for	IN
cord-003130-p2h8p5bm	52	32	POWV	POWV	NNP
cord-003130-p2h8p5bm	52	33	infection	infection	NN
cord-003130-p2h8p5bm	52	34	,	,	,
cord-003130-p2h8p5bm	52	35	neurons	neuron	NNS
cord-003130-p2h8p5bm	52	36	have	have	VBP
cord-003130-p2h8p5bm	52	37	been	be	VBN
cord-003130-p2h8p5bm	52	38	shown	show	VBN
cord-003130-p2h8p5bm	52	39	to	to	TO
cord-003130-p2h8p5bm	52	40	be	be	VB
cord-003130-p2h8p5bm	52	41	the	the	DT
cord-003130-p2h8p5bm	52	42	primary	primary	JJ
cord-003130-p2h8p5bm	52	43	target	target	NN
cord-003130-p2h8p5bm	52	44	for	for	IN
cord-003130-p2h8p5bm	52	45	POWV	POWV	NNP
cord-003130-p2h8p5bm	52	46	in	in	IN
cord-003130-p2h8p5bm	52	47	mice	mouse	NNS
cord-003130-p2h8p5bm	52	48	and	and	CC
cord-003130-p2h8p5bm	52	49	humans	human	NNS
cord-003130-p2h8p5bm	52	50	[	[	-LRB-
cord-003130-p2h8p5bm	52	51	52	52	CD
cord-003130-p2h8p5bm	52	52	,	,	,
cord-003130-p2h8p5bm	52	53	53	53	CD
cord-003130-p2h8p5bm	52	54	]	]	-RRB-
cord-003130-p2h8p5bm	52	55	.	.	.
cord-003130-p2h8p5bm	53	1	During	during	IN
cord-003130-p2h8p5bm	53	2	the	the	DT
cord-003130-p2h8p5bm	53	3	last	last	JJ
cord-003130-p2h8p5bm	53	4	10	10	CD
cord-003130-p2h8p5bm	53	5	years	year	NNS
cord-003130-p2h8p5bm	53	6	there	there	EX
cord-003130-p2h8p5bm	53	7	has	have	VBZ
cord-003130-p2h8p5bm	53	8	been	be	VBN
cord-003130-p2h8p5bm	53	9	an	an	DT
cord-003130-p2h8p5bm	53	10	increase	increase	NN
cord-003130-p2h8p5bm	53	11	of	of	IN
cord-003130-p2h8p5bm	53	12	POWV	POWV	NNP
cord-003130-p2h8p5bm	53	13	in	in	IN
cord-003130-p2h8p5bm	53	14	the	the	DT
cord-003130-p2h8p5bm	53	15	USA	USA	NNP
cord-003130-p2h8p5bm	53	16	with	with	IN
cord-003130-p2h8p5bm	53	17	approximately	approximately	RB
cord-003130-p2h8p5bm	53	18	100	100	CD
cord-003130-p2h8p5bm	53	19	reported	report	VBN
cord-003130-p2h8p5bm	53	20	cases	case	NNS
cord-003130-p2h8p5bm	53	21	[	[	-LRB-
cord-003130-p2h8p5bm	53	22	54	54	CD
cord-003130-p2h8p5bm	53	23	,	,	,
cord-003130-p2h8p5bm	53	24	55	55	CD
cord-003130-p2h8p5bm	53	25	]	]	-RRB-
cord-003130-p2h8p5bm	53	26	.	.	.
cord-003130-p2h8p5bm	54	1	The	the	DT
cord-003130-p2h8p5bm	54	2	recent	recent	JJ
cord-003130-p2h8p5bm	54	3	rise	rise	NN
cord-003130-p2h8p5bm	54	4	in	in	IN
cord-003130-p2h8p5bm	54	5	incidence	incidence	NN
cord-003130-p2h8p5bm	54	6	could	could	MD
cord-003130-p2h8p5bm	54	7	be	be	VB
cord-003130-p2h8p5bm	54	8	due	due	JJ
cord-003130-p2h8p5bm	54	9	to	to	IN
cord-003130-p2h8p5bm	54	10	increased	increase	VBN
cord-003130-p2h8p5bm	54	11	surveillance	surveillance	NN
cord-003130-p2h8p5bm	54	12	and	and	CC
cord-003130-p2h8p5bm	54	13	diagnosis	diagnosis	NN
cord-003130-p2h8p5bm	54	14	of	of	IN
cord-003130-p2h8p5bm	54	15	POWV	POWV	NNP
cord-003130-p2h8p5bm	54	16	,	,	,
cord-003130-p2h8p5bm	54	17	or	or	CC
cord-003130-p2h8p5bm	54	18	it	-PRON-	PRP
cord-003130-p2h8p5bm	54	19	may	may	MD
cord-003130-p2h8p5bm	54	20	represent	represent	VB
cord-003130-p2h8p5bm	54	21	a	a	DT
cord-003130-p2h8p5bm	54	22	true	true	JJ
cord-003130-p2h8p5bm	54	23	emergence	emergence	NN
cord-003130-p2h8p5bm	54	24	of	of	IN
cord-003130-p2h8p5bm	54	25	the	the	DT
cord-003130-p2h8p5bm	54	26	disease	disease	NN
cord-003130-p2h8p5bm	54	27	in	in	IN
cord-003130-p2h8p5bm	54	28	endemic	endemic	JJ
cord-003130-p2h8p5bm	54	29	areas	area	NNS
cord-003130-p2h8p5bm	54	30	,	,	,
cord-003130-p2h8p5bm	54	31	or	or	CC
cord-003130-p2h8p5bm	54	32	both	both	DT
cord-003130-p2h8p5bm	54	33	[	[	-LRB-
cord-003130-p2h8p5bm	54	34	55	55	CD
cord-003130-p2h8p5bm	54	35	]	]	-RRB-
cord-003130-p2h8p5bm	54	36	.	.	.
cord-003130-p2h8p5bm	55	1	The	the	DT
cord-003130-p2h8p5bm	55	2	incubation	incubation	NN
cord-003130-p2h8p5bm	55	3	period	period	NN
cord-003130-p2h8p5bm	55	4	ranges	range	VBZ
cord-003130-p2h8p5bm	55	5	from	from	IN
cord-003130-p2h8p5bm	55	6	1	1	CD
cord-003130-p2h8p5bm	55	7	week	week	NN
cord-003130-p2h8p5bm	55	8	to	to	IN
cord-003130-p2h8p5bm	55	9	1	1	CD
cord-003130-p2h8p5bm	55	10	month	month	NN
cord-003130-p2h8p5bm	55	11	.	.	.
cord-003130-p2h8p5bm	56	1	The	the	DT
cord-003130-p2h8p5bm	56	2	symptoms	symptom	NNS
cord-003130-p2h8p5bm	56	3	of	of	IN
cord-003130-p2h8p5bm	56	4	POWV	POWV	NNP
cord-003130-p2h8p5bm	56	5	infection	infection	NN
cord-003130-p2h8p5bm	56	6	may	may	MD
cord-003130-p2h8p5bm	56	7	include	include	VB
cord-003130-p2h8p5bm	56	8	fever	fever	NN
cord-003130-p2h8p5bm	56	9	,	,	,
cord-003130-p2h8p5bm	56	10	headache	headache	NN
cord-003130-p2h8p5bm	56	11	,	,	,
cord-003130-p2h8p5bm	56	12	vomiting	vomiting	NN
cord-003130-p2h8p5bm	56	13	,	,	,
cord-003130-p2h8p5bm	56	14	weakness	weakness	NN
cord-003130-p2h8p5bm	56	15	,	,	,
cord-003130-p2h8p5bm	56	16	confusion	confusion	NN
cord-003130-p2h8p5bm	56	17	,	,	,
cord-003130-p2h8p5bm	56	18	seizures	seizure	NNS
cord-003130-p2h8p5bm	56	19	,	,	,
cord-003130-p2h8p5bm	56	20	and	and	CC
cord-003130-p2h8p5bm	56	21	memory	memory	NN
cord-003130-p2h8p5bm	56	22	loss	loss	NN
cord-003130-p2h8p5bm	56	23	with	with	IN
cord-003130-p2h8p5bm	56	24	a	a	DT
cord-003130-p2h8p5bm	56	25	case	case	NN
cord-003130-p2h8p5bm	56	26	fatality	fatality	NN
cord-003130-p2h8p5bm	56	27	rate	rate	NN
cord-003130-p2h8p5bm	56	28	of	of	IN
cord-003130-p2h8p5bm	56	29	10	10	CD
cord-003130-p2h8p5bm	56	30	%	%	NN
cord-003130-p2h8p5bm	56	31	[	[	-LRB-
cord-003130-p2h8p5bm	56	32	54	54	CD
cord-003130-p2h8p5bm	56	33	]	]	-RRB-
cord-003130-p2h8p5bm	56	34	.	.	.
cord-003130-p2h8p5bm	57	1	Approximately	approximately	RB
cord-003130-p2h8p5bm	57	2	half	half	NN
cord-003130-p2h8p5bm	57	3	of	of	IN
cord-003130-p2h8p5bm	57	4	the	the	DT
cord-003130-p2h8p5bm	57	5	survivors	survivor	NNS
cord-003130-p2h8p5bm	57	6	experience	experience	VBP
cord-003130-p2h8p5bm	57	7	permanent	permanent	JJ
cord-003130-p2h8p5bm	57	8	neurological	neurological	JJ
cord-003130-p2h8p5bm	57	9	symptoms	symptom	NNS
cord-003130-p2h8p5bm	57	10	,	,	,
cord-003130-p2h8p5bm	57	11	such	such	JJ
cord-003130-p2h8p5bm	57	12	as	as	IN
cord-003130-p2h8p5bm	57	13	recurrent	recurrent	JJ
cord-003130-p2h8p5bm	57	14	headaches	headache	NNS
cord-003130-p2h8p5bm	57	15	,	,	,
cord-003130-p2h8p5bm	57	16	muscle	muscle	NN
cord-003130-p2h8p5bm	57	17	wasting	wasting	NN
cord-003130-p2h8p5bm	57	18	,	,	,
cord-003130-p2h8p5bm	57	19	and	and	CC
cord-003130-p2h8p5bm	57	20	memory	memory	NN
cord-003130-p2h8p5bm	57	21	problems	problem	NNS
cord-003130-p2h8p5bm	57	22	(	(	-LRB-
cord-003130-p2h8p5bm	57	23	https://www.CDC.gov	https://www.CDC.gov	NNP
cord-003130-p2h8p5bm	57	24	)	)	-RRB-
cord-003130-p2h8p5bm	57	25	.	.	.
cord-003130-p2h8p5bm	58	1	There	there	EX
cord-003130-p2h8p5bm	58	2	are	be	VBP
cord-003130-p2h8p5bm	58	3	no	no	DT
cord-003130-p2h8p5bm	58	4	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	58	5	treatments	treatment	NNS
cord-003130-p2h8p5bm	58	6	or	or	CC
cord-003130-p2h8p5bm	58	7	vaccines	vaccine	NNS
cord-003130-p2h8p5bm	58	8	available	available	JJ
cord-003130-p2h8p5bm	58	9	against	against	IN
cord-003130-p2h8p5bm	58	10	POWV	POWV	NNP
cord-003130-p2h8p5bm	58	11	.	.	.
cord-003130-p2h8p5bm	59	1	LIV	LIV	NNP
cord-003130-p2h8p5bm	59	2	is	be	VBZ
cord-003130-p2h8p5bm	59	3	mainly	mainly	RB
cord-003130-p2h8p5bm	59	4	distributed	distribute	VBN
cord-003130-p2h8p5bm	59	5	in	in	IN
cord-003130-p2h8p5bm	59	6	the	the	DT
cord-003130-p2h8p5bm	59	7	UK	UK	NNP
cord-003130-p2h8p5bm	59	8	and	and	CC
cord-003130-p2h8p5bm	59	9	Ireland	Ireland	NNP
cord-003130-p2h8p5bm	59	10	,	,	,
cord-003130-p2h8p5bm	59	11	but	but	CC
cord-003130-p2h8p5bm	59	12	it	-PRON-	PRP
cord-003130-p2h8p5bm	59	13	has	have	VBZ
cord-003130-p2h8p5bm	59	14	also	also	RB
cord-003130-p2h8p5bm	59	15	been	be	VBN
cord-003130-p2h8p5bm	59	16	detected	detect	VBN
cord-003130-p2h8p5bm	59	17	in	in	IN
cord-003130-p2h8p5bm	59	18	sheep	sheep	NNS
cord-003130-p2h8p5bm	59	19	in	in	IN
cord-003130-p2h8p5bm	59	20	Norway	Norway	NNP
cord-003130-p2h8p5bm	59	21	and	and	CC
cord-003130-p2h8p5bm	59	22	on	on	IN
cord-003130-p2h8p5bm	59	23	the	the	DT
cord-003130-p2h8p5bm	59	24	Bornholm	Bornholm	NNP
cord-003130-p2h8p5bm	59	25	island	island	NN
cord-003130-p2h8p5bm	59	26	in	in	IN
cord-003130-p2h8p5bm	59	27	Denmark	Denmark	NNP
cord-003130-p2h8p5bm	59	28	(	(	-LRB-
cord-003130-p2h8p5bm	59	29	Figure	figure	NN
cord-003130-p2h8p5bm	59	30	1	1	CD
cord-003130-p2h8p5bm	59	31	)	)	-RRB-
cord-003130-p2h8p5bm	59	32	.	.	.
cord-003130-p2h8p5bm	60	1	LIV	LIV	NNP
cord-003130-p2h8p5bm	60	2	is	be	VBZ
cord-003130-p2h8p5bm	60	3	most	most	RBS
cord-003130-p2h8p5bm	60	4	commonly	commonly	RB
cord-003130-p2h8p5bm	60	5	known	know	VBN
cord-003130-p2h8p5bm	60	6	as	as	IN
cord-003130-p2h8p5bm	60	7	pathogen	pathogen	NN
cord-003130-p2h8p5bm	60	8	of	of	IN
cord-003130-p2h8p5bm	60	9	sheep	sheep	NNS
cord-003130-p2h8p5bm	60	10	and	and	CC
cord-003130-p2h8p5bm	60	11	red	red	JJ
cord-003130-p2h8p5bm	60	12	grouse	grouse	NN
cord-003130-p2h8p5bm	60	13	although	although	IN
cord-003130-p2h8p5bm	60	14	humans	human	NNS
cord-003130-p2h8p5bm	60	15	can	can	MD
cord-003130-p2h8p5bm	60	16	also	also	RB
cord-003130-p2h8p5bm	60	17	get	get	VB
cord-003130-p2h8p5bm	60	18	infected	infect	VBN
cord-003130-p2h8p5bm	60	19	[	[	-LRB-
cord-003130-p2h8p5bm	60	20	17	17	CD
cord-003130-p2h8p5bm	60	21	,	,	,
cord-003130-p2h8p5bm	60	22	56	56	CD
cord-003130-p2h8p5bm	60	23	]	]	-RRB-
cord-003130-p2h8p5bm	60	24	.	.	.
cord-003130-p2h8p5bm	61	1	Animals	animal	NNS
cord-003130-p2h8p5bm	61	2	develop	develop	VBP
cord-003130-p2h8p5bm	61	3	a	a	DT
cord-003130-p2h8p5bm	61	4	febrile	febrile	JJ
cord-003130-p2h8p5bm	61	5	disease	disease	NN
cord-003130-p2h8p5bm	61	6	,	,	,
cord-003130-p2h8p5bm	61	7	which	which	WDT
cord-003130-p2h8p5bm	61	8	can	can	MD
cord-003130-p2h8p5bm	61	9	progress	progress	VB
cord-003130-p2h8p5bm	61	10	to	to	IN
cord-003130-p2h8p5bm	61	11	fatal	fatal	JJ
cord-003130-p2h8p5bm	61	12	encephalitis	encephalitis	RB
cord-003130-p2h8p5bm	61	13	[	[	-LRB-
cord-003130-p2h8p5bm	61	14	57	57	CD
cord-003130-p2h8p5bm	61	15	]	]	-RRB-
cord-003130-p2h8p5bm	61	16	.	.	.
cord-003130-p2h8p5bm	62	1	Like	like	IN
cord-003130-p2h8p5bm	62	2	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	62	3	,	,	,
cord-003130-p2h8p5bm	62	4	the	the	DT
cord-003130-p2h8p5bm	62	5	vector	vector	NN
cord-003130-p2h8p5bm	62	6	of	of	IN
cord-003130-p2h8p5bm	62	7	LIV	LIV	NNP
cord-003130-p2h8p5bm	62	8	is	be	VBZ
cord-003130-p2h8p5bm	62	9	the	the	DT
cord-003130-p2h8p5bm	62	10	tick	tick	NN
cord-003130-p2h8p5bm	62	11	species	specie	NNS
cord-003130-p2h8p5bm	62	12	Ixodes	Ixodes	NNP
cord-003130-p2h8p5bm	62	13	ricinus	ricinus	VBP
cord-003130-p2h8p5bm	62	14	[	[	-LRB-
cord-003130-p2h8p5bm	62	15	57	57	CD
cord-003130-p2h8p5bm	62	16	]	]	-RRB-
cord-003130-p2h8p5bm	62	17	.	.	.
cord-003130-p2h8p5bm	63	1	Ticks	tick	NNS
cord-003130-p2h8p5bm	63	2	transmit	transmit	VBP
cord-003130-p2h8p5bm	63	3	the	the	DT
cord-003130-p2h8p5bm	63	4	virus	virus	NN
cord-003130-p2h8p5bm	63	5	to	to	IN
cord-003130-p2h8p5bm	63	6	animals	animal	NNS
cord-003130-p2h8p5bm	63	7	,	,	,
cord-003130-p2h8p5bm	63	8	however	however	RB
cord-003130-p2h8p5bm	63	9	,	,	,
cord-003130-p2h8p5bm	63	10	natural	natural	JJ
cord-003130-p2h8p5bm	63	11	exposure	exposure	NN
cord-003130-p2h8p5bm	63	12	to	to	IN
cord-003130-p2h8p5bm	63	13	humans	human	NNS
cord-003130-p2h8p5bm	63	14	is	be	VBZ
cord-003130-p2h8p5bm	63	15	rare	rare	JJ
cord-003130-p2h8p5bm	63	16	[	[	-LRB-
cord-003130-p2h8p5bm	63	17	33	33	CD
cord-003130-p2h8p5bm	63	18	]	]	-RRB-
cord-003130-p2h8p5bm	63	19	.	.	.
cord-003130-p2h8p5bm	64	1	Instead	instead	RB
cord-003130-p2h8p5bm	64	2	humans	human	NNS
cord-003130-p2h8p5bm	64	3	that	that	WDT
cord-003130-p2h8p5bm	64	4	are	be	VBP
cord-003130-p2h8p5bm	64	5	exposed	expose	VBN
cord-003130-p2h8p5bm	64	6	to	to	IN
cord-003130-p2h8p5bm	64	7	infected	infected	JJ
cord-003130-p2h8p5bm	64	8	animals	animal	NNS
cord-003130-p2h8p5bm	64	9	such	such	JJ
cord-003130-p2h8p5bm	64	10	as	as	IN
cord-003130-p2h8p5bm	64	11	veterinarians	veterinarian	NNS
cord-003130-p2h8p5bm	64	12	,	,	,
cord-003130-p2h8p5bm	64	13	farmers	farmer	NNS
cord-003130-p2h8p5bm	64	14	,	,	,
cord-003130-p2h8p5bm	64	15	butchers	butcher	NNS
cord-003130-p2h8p5bm	64	16	,	,	,
cord-003130-p2h8p5bm	64	17	and	and	CC
cord-003130-p2h8p5bm	64	18	abattoir	abattoir	NN
cord-003130-p2h8p5bm	64	19	workers	worker	NNS
cord-003130-p2h8p5bm	64	20	,	,	,
cord-003130-p2h8p5bm	64	21	as	as	RB
cord-003130-p2h8p5bm	64	22	well	well	RB
cord-003130-p2h8p5bm	64	23	as	as	IN
cord-003130-p2h8p5bm	64	24	laboratory	laboratory	NN
cord-003130-p2h8p5bm	64	25	scientists	scientist	NNS
cord-003130-p2h8p5bm	64	26	have	have	VBP
cord-003130-p2h8p5bm	64	27	acquired	acquire	VBN
cord-003130-p2h8p5bm	64	28	LIV	LIV	NNP
cord-003130-p2h8p5bm	64	29	infection	infection	NN
cord-003130-p2h8p5bm	64	30	[	[	-LRB-
cord-003130-p2h8p5bm	64	31	58	58	CD
cord-003130-p2h8p5bm	64	32	]	]	-RRB-
cord-003130-p2h8p5bm	64	33	[	[	-LRB-
cord-003130-p2h8p5bm	64	34	59	59	CD
cord-003130-p2h8p5bm	64	35	]	]	-RRB-
cord-003130-p2h8p5bm	64	36	[	[	-LRB-
cord-003130-p2h8p5bm	64	37	60	60	CD
cord-003130-p2h8p5bm	64	38	]	]	-RRB-
cord-003130-p2h8p5bm	64	39	[	[	-LRB-
cord-003130-p2h8p5bm	64	40	61	61	CD
cord-003130-p2h8p5bm	64	41	]	]	-RRB-
cord-003130-p2h8p5bm	64	42	.	.	.
cord-003130-p2h8p5bm	65	1	In	in	IN
cord-003130-p2h8p5bm	65	2	between	between	IN
cord-003130-p2h8p5bm	65	3	the	the	DT
cord-003130-p2h8p5bm	65	4	years	year	NNS
cord-003130-p2h8p5bm	65	5	of	of	IN
cord-003130-p2h8p5bm	65	6	1934	1934	CD
cord-003130-p2h8p5bm	65	7	and	and	CC
cord-003130-p2h8p5bm	65	8	1991	1991	CD
cord-003130-p2h8p5bm	65	9	,	,	,
cord-003130-p2h8p5bm	65	10	31	31	CD
cord-003130-p2h8p5bm	65	11	human	human	JJ
cord-003130-p2h8p5bm	65	12	cases	case	NNS
cord-003130-p2h8p5bm	65	13	of	of	IN
cord-003130-p2h8p5bm	65	14	LIV	LIV	NNP
cord-003130-p2h8p5bm	65	15	was	be	VBD
cord-003130-p2h8p5bm	65	16	described	describe	VBN
cord-003130-p2h8p5bm	65	17	[	[	-LRB-
cord-003130-p2h8p5bm	65	18	62	62	CD
cord-003130-p2h8p5bm	65	19	]	]	-RRB-
cord-003130-p2h8p5bm	65	20	.	.	.
cord-003130-p2h8p5bm	66	1	In	in	IN
cord-003130-p2h8p5bm	66	2	humans	human	NNS
cord-003130-p2h8p5bm	66	3	,	,	,
cord-003130-p2h8p5bm	66	4	LIV	LIV	NNP
cord-003130-p2h8p5bm	66	5	causes	cause	VBZ
cord-003130-p2h8p5bm	66	6	a	a	DT
cord-003130-p2h8p5bm	66	7	disease	disease	NN
cord-003130-p2h8p5bm	66	8	that	that	WDT
cord-003130-p2h8p5bm	66	9	closely	closely	RB
cord-003130-p2h8p5bm	66	10	resembles	resemble	VBZ
cord-003130-p2h8p5bm	66	11	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	66	12	,	,	,
cord-003130-p2h8p5bm	66	13	with	with	IN
cord-003130-p2h8p5bm	66	14	initial	initial	JJ
cord-003130-p2h8p5bm	66	15	flu	flu	NN
cord-003130-p2h8p5bm	66	16	-	-	HYPH
cord-003130-p2h8p5bm	66	17	like	like	JJ
cord-003130-p2h8p5bm	66	18	symptoms	symptom	NNS
cord-003130-p2h8p5bm	66	19	which	which	WDT
cord-003130-p2h8p5bm	66	20	can	can	MD
cord-003130-p2h8p5bm	66	21	progress	progress	VB
cord-003130-p2h8p5bm	66	22	to	to	IN
cord-003130-p2h8p5bm	66	23	severe	severe	JJ
cord-003130-p2h8p5bm	66	24	neurological	neurological	JJ
cord-003130-p2h8p5bm	66	25	disease	disease	NN
cord-003130-p2h8p5bm	66	26	.	.	.
cord-003130-p2h8p5bm	67	1	Distinct	distinct	JJ
cord-003130-p2h8p5bm	67	2	but	but	CC
cord-003130-p2h8p5bm	67	3	closely	closely	RB
cord-003130-p2h8p5bm	67	4	related	related	JJ
cord-003130-p2h8p5bm	67	5	viruses	virus	NNS
cord-003130-p2h8p5bm	67	6	are	be	VBP
cord-003130-p2h8p5bm	67	7	also	also	RB
cord-003130-p2h8p5bm	67	8	found	find	VBN
cord-003130-p2h8p5bm	67	9	in	in	IN
cord-003130-p2h8p5bm	67	10	Spain	Spain	NNP
cord-003130-p2h8p5bm	67	11	(	(	-LRB-
cord-003130-p2h8p5bm	67	12	Spanish	spanish	JJ
cord-003130-p2h8p5bm	67	13	sheep	sheep	NN
cord-003130-p2h8p5bm	67	14	encephalomyelitis	encephalomyelitis	NN
cord-003130-p2h8p5bm	67	15	virus	virus	NN
cord-003130-p2h8p5bm	67	16	)	)	-RRB-
cord-003130-p2h8p5bm	67	17	,	,	,
cord-003130-p2h8p5bm	67	18	Turkey	Turkey	NNP
cord-003130-p2h8p5bm	67	19	(	(	-LRB-
cord-003130-p2h8p5bm	67	20	Turkish	turkish	JJ
cord-003130-p2h8p5bm	67	21	sheep	sheep	NNS
cord-003130-p2h8p5bm	67	22	encephalitis	encephalitis	NN
cord-003130-p2h8p5bm	67	23	virus	virus	NN
cord-003130-p2h8p5bm	67	24	)	)	-RRB-
cord-003130-p2h8p5bm	67	25	,	,	,
cord-003130-p2h8p5bm	67	26	and	and	CC
cord-003130-p2h8p5bm	67	27	Greece	Greece	NNP
cord-003130-p2h8p5bm	67	28	(	(	-LRB-
cord-003130-p2h8p5bm	67	29	Greek	greek	JJ
cord-003130-p2h8p5bm	67	30	goat	goat	NN
cord-003130-p2h8p5bm	67	31	encephalitis	encephalitis	NN
cord-003130-p2h8p5bm	67	32	virus	virus	NN
cord-003130-p2h8p5bm	67	33	)	)	-RRB-
cord-003130-p2h8p5bm	67	34	[	[	-LRB-
cord-003130-p2h8p5bm	67	35	33	33	CD
cord-003130-p2h8p5bm	67	36	]	]	-RRB-
cord-003130-p2h8p5bm	67	37	.	.	.
cord-003130-p2h8p5bm	68	1	OHFV	OHFV	NNP
cord-003130-p2h8p5bm	68	2	distribution	distribution	NN
cord-003130-p2h8p5bm	68	3	is	be	VBZ
cord-003130-p2h8p5bm	68	4	restricted	restrict	VBN
cord-003130-p2h8p5bm	68	5	to	to	IN
cord-003130-p2h8p5bm	68	6	western	western	JJ
cord-003130-p2h8p5bm	68	7	Siberia	Siberia	NNP
cord-003130-p2h8p5bm	68	8	(	(	-LRB-
cord-003130-p2h8p5bm	68	9	Figure	figure	NN
cord-003130-p2h8p5bm	68	10	1	1	CD
cord-003130-p2h8p5bm	68	11	)	)	-RRB-
cord-003130-p2h8p5bm	68	12	[	[	-LRB-
cord-003130-p2h8p5bm	68	13	17	17	CD
cord-003130-p2h8p5bm	68	14	]	]	-RRB-
cord-003130-p2h8p5bm	68	15	.	.	.
cord-003130-p2h8p5bm	69	1	The	the	DT
cord-003130-p2h8p5bm	69	2	main	main	JJ
cord-003130-p2h8p5bm	69	3	vector	vector	NN
cord-003130-p2h8p5bm	69	4	of	of	IN
cord-003130-p2h8p5bm	69	5	OHFV	OHFV	NNP
cord-003130-p2h8p5bm	69	6	is	be	VBZ
cord-003130-p2h8p5bm	69	7	the	the	DT
cord-003130-p2h8p5bm	69	8	meadow	meadow	NN
cord-003130-p2h8p5bm	69	9	tick	tick	NN
cord-003130-p2h8p5bm	69	10	,	,	,
cord-003130-p2h8p5bm	69	11	Dermacentor	Dermacentor	NNP
cord-003130-p2h8p5bm	69	12	reticulatus	reticulatus	NN
cord-003130-p2h8p5bm	69	13	,	,	,
cord-003130-p2h8p5bm	69	14	which	which	WDT
cord-003130-p2h8p5bm	69	15	can	can	MD
cord-003130-p2h8p5bm	69	16	also	also	RB
cord-003130-p2h8p5bm	69	17	transmit	transmit	VB
cord-003130-p2h8p5bm	69	18	the	the	DT
cord-003130-p2h8p5bm	69	19	virus	virus	NN
cord-003130-p2h8p5bm	69	20	to	to	IN
cord-003130-p2h8p5bm	69	21	humans	human	NNS
cord-003130-p2h8p5bm	69	22	.	.	.
cord-003130-p2h8p5bm	70	1	However	however	RB
cord-003130-p2h8p5bm	70	2	,	,	,
cord-003130-p2h8p5bm	70	3	humans	human	NNS
cord-003130-p2h8p5bm	70	4	are	be	VBP
cord-003130-p2h8p5bm	70	5	mainly	mainly	RB
cord-003130-p2h8p5bm	70	6	infected	infect	VBN
cord-003130-p2h8p5bm	70	7	after	after	IN
cord-003130-p2h8p5bm	70	8	contact	contact	NN
cord-003130-p2h8p5bm	70	9	with	with	IN
cord-003130-p2h8p5bm	70	10	infected	infected	JJ
cord-003130-p2h8p5bm	70	11	muskrats	muskrat	NNS
cord-003130-p2h8p5bm	70	12	(	(	-LRB-
cord-003130-p2h8p5bm	70	13	Ondatra	Ondatra	NNP
cord-003130-p2h8p5bm	70	14	zibethicus	zibethicus	NNP
cord-003130-p2h8p5bm	70	15	)	)	-RRB-
cord-003130-p2h8p5bm	70	16	which	which	WDT
cord-003130-p2h8p5bm	70	17	are	be	VBP
cord-003130-p2h8p5bm	70	18	very	very	RB
cord-003130-p2h8p5bm	70	19	sensitive	sensitive	JJ
cord-003130-p2h8p5bm	70	20	to	to	IN
cord-003130-p2h8p5bm	70	21	the	the	DT
cord-003130-p2h8p5bm	70	22	infection	infection	NN
cord-003130-p2h8p5bm	70	23	and	and	CC
cord-003130-p2h8p5bm	70	24	often	often	RB
cord-003130-p2h8p5bm	70	25	succumb	succumb	VBP
cord-003130-p2h8p5bm	70	26	to	to	IN
cord-003130-p2h8p5bm	70	27	the	the	DT
cord-003130-p2h8p5bm	70	28	infection	infection	NN
cord-003130-p2h8p5bm	70	29	[	[	-LRB-
cord-003130-p2h8p5bm	70	30	63	63	CD
cord-003130-p2h8p5bm	70	31	]	]	-RRB-
cord-003130-p2h8p5bm	70	32	.	.	.
cord-003130-p2h8p5bm	71	1	Muskrats	muskrat	NNS
cord-003130-p2h8p5bm	71	2	develop	develop	VBP
cord-003130-p2h8p5bm	71	3	high	high	JJ
cord-003130-p2h8p5bm	71	4	viremia	viremia	NN
cord-003130-p2h8p5bm	71	5	which	which	WDT
cord-003130-p2h8p5bm	71	6	can	can	MD
cord-003130-p2h8p5bm	71	7	last	last	VB
cord-003130-p2h8p5bm	71	8	for	for	IN
cord-003130-p2h8p5bm	71	9	several	several	JJ
cord-003130-p2h8p5bm	71	10	weeks	week	NNS
cord-003130-p2h8p5bm	71	11	.	.	.
cord-003130-p2h8p5bm	72	1	Human	human	JJ
cord-003130-p2h8p5bm	72	2	infection	infection	NN
cord-003130-p2h8p5bm	72	3	occurs	occur	VBZ
cord-003130-p2h8p5bm	72	4	through	through	IN
cord-003130-p2h8p5bm	72	5	contact	contact	NN
cord-003130-p2h8p5bm	72	6	with	with	IN
cord-003130-p2h8p5bm	72	7	urine	urine	NN
cord-003130-p2h8p5bm	72	8	,	,	,
cord-003130-p2h8p5bm	72	9	feces	fece	NNS
cord-003130-p2h8p5bm	72	10	,	,	,
cord-003130-p2h8p5bm	72	11	and	and	CC
cord-003130-p2h8p5bm	72	12	blood	blood	NN
cord-003130-p2h8p5bm	72	13	[	[	-LRB-
cord-003130-p2h8p5bm	72	14	63	63	CD
cord-003130-p2h8p5bm	72	15	]	]	-RRB-
cord-003130-p2h8p5bm	72	16	.	.	.
cord-003130-p2h8p5bm	73	1	Secretion	secretion	NN
cord-003130-p2h8p5bm	73	2	of	of	IN
cord-003130-p2h8p5bm	73	3	OHFV	OHFV	NNP
cord-003130-p2h8p5bm	73	4	in	in	IN
cord-003130-p2h8p5bm	73	5	unpasteurized	unpasteurized	JJ
cord-003130-p2h8p5bm	73	6	goat	goat	NN
cord-003130-p2h8p5bm	73	7	milk	milk	NN
cord-003130-p2h8p5bm	73	8	has	have	VBZ
cord-003130-p2h8p5bm	73	9	been	be	VBN
cord-003130-p2h8p5bm	73	10	reported	report	VBN
cord-003130-p2h8p5bm	73	11	but	but	CC
cord-003130-p2h8p5bm	73	12	no	no	DT
cord-003130-p2h8p5bm	73	13	milk	milk	NN
cord-003130-p2h8p5bm	73	14	-	-	HYPH
cord-003130-p2h8p5bm	73	15	borne	bear	VBN
cord-003130-p2h8p5bm	73	16	outbreaks	outbreak	NNS
cord-003130-p2h8p5bm	73	17	have	have	VBP
cord-003130-p2h8p5bm	73	18	been	be	VBN
cord-003130-p2h8p5bm	73	19	observed	observe	VBN
cord-003130-p2h8p5bm	73	20	[	[	-LRB-
cord-003130-p2h8p5bm	73	21	63	63	CD
cord-003130-p2h8p5bm	73	22	]	]	-RRB-
cord-003130-p2h8p5bm	73	23	.	.	.
cord-003130-p2h8p5bm	74	1	The	the	DT
cord-003130-p2h8p5bm	74	2	exact	exact	JJ
cord-003130-p2h8p5bm	74	3	number	number	NN
cord-003130-p2h8p5bm	74	4	of	of	IN
cord-003130-p2h8p5bm	74	5	annual	annual	JJ
cord-003130-p2h8p5bm	74	6	cases	case	NNS
cord-003130-p2h8p5bm	74	7	are	be	VBP
cord-003130-p2h8p5bm	74	8	uncertain	uncertain	JJ
cord-003130-p2h8p5bm	74	9	because	because	IN
cord-003130-p2h8p5bm	74	10	of	of	IN
cord-003130-p2h8p5bm	74	11	misdiagnoses	misdiagnose	NNS
cord-003130-p2h8p5bm	74	12	and	and	CC
cord-003130-p2h8p5bm	74	13	unreported	unreported	JJ
cord-003130-p2h8p5bm	74	14	cases	case	NNS
cord-003130-p2h8p5bm	74	15	,	,	,
cord-003130-p2h8p5bm	74	16	but	but	CC
cord-003130-p2h8p5bm	74	17	165	165	CD
cord-003130-p2h8p5bm	74	18	cases	case	NNS
cord-003130-p2h8p5bm	74	19	were	be	VBD
cord-003130-p2h8p5bm	74	20	reported	report	VBN
cord-003130-p2h8p5bm	74	21	between	between	IN
cord-003130-p2h8p5bm	74	22	1988	1988	CD
cord-003130-p2h8p5bm	74	23	and	and	CC
cord-003130-p2h8p5bm	74	24	1997	1997	CD
cord-003130-p2h8p5bm	74	25	[	[	-LRB-
cord-003130-p2h8p5bm	74	26	63	63	CD
cord-003130-p2h8p5bm	74	27	]	]	-RRB-
cord-003130-p2h8p5bm	74	28	.	.	.
cord-003130-p2h8p5bm	75	1	OHFV	OHFV	NNP
cord-003130-p2h8p5bm	75	2	may	may	MD
cord-003130-p2h8p5bm	75	3	cause	cause	VB
cord-003130-p2h8p5bm	75	4	a	a	DT
cord-003130-p2h8p5bm	75	5	biphasic	biphasic	JJ
cord-003130-p2h8p5bm	75	6	disease	disease	NN
cord-003130-p2h8p5bm	75	7	;	;	:
cord-003130-p2h8p5bm	75	8	the	the	DT
cord-003130-p2h8p5bm	75	9	initial	initial	JJ
cord-003130-p2h8p5bm	75	10	phase	phase	NN
cord-003130-p2h8p5bm	75	11	is	be	VBZ
cord-003130-p2h8p5bm	75	12	characterized	characterize	VBN
cord-003130-p2h8p5bm	75	13	by	by	IN
cord-003130-p2h8p5bm	75	14	high	high	JJ
cord-003130-p2h8p5bm	75	15	fever	fever	NN
cord-003130-p2h8p5bm	75	16	,	,	,
cord-003130-p2h8p5bm	75	17	bleeding	bleed	VBG
cord-003130-p2h8p5bm	75	18	from	from	IN
cord-003130-p2h8p5bm	75	19	the	the	DT
cord-003130-p2h8p5bm	75	20	nose	nose	NN
cord-003130-p2h8p5bm	75	21	,	,	,
cord-003130-p2h8p5bm	75	22	mouth	mouth	NN
cord-003130-p2h8p5bm	75	23	,	,	,
cord-003130-p2h8p5bm	75	24	and	and	CC
cord-003130-p2h8p5bm	75	25	uterus	uterus	NN
cord-003130-p2h8p5bm	75	26	.	.	.
cord-003130-p2h8p5bm	76	1	Thirty	thirty	CD
cord-003130-p2h8p5bm	76	2	to	to	TO
cord-003130-p2h8p5bm	76	3	fifty	fifty	CD
cord-003130-p2h8p5bm	76	4	percent	percent	NN
cord-003130-p2h8p5bm	76	5	of	of	IN
cord-003130-p2h8p5bm	76	6	the	the	DT
cord-003130-p2h8p5bm	76	7	cases	case	NNS
cord-003130-p2h8p5bm	76	8	experience	experience	VBP
cord-003130-p2h8p5bm	76	9	a	a	DT
cord-003130-p2h8p5bm	76	10	second	second	JJ
cord-003130-p2h8p5bm	76	11	phase	phase	NN
cord-003130-p2h8p5bm	76	12	characterized	characterize	VBN
cord-003130-p2h8p5bm	76	13	by	by	IN
cord-003130-p2h8p5bm	76	14	high	high	JJ
cord-003130-p2h8p5bm	76	15	fever	fever	NN
cord-003130-p2h8p5bm	76	16	and	and	CC
cord-003130-p2h8p5bm	76	17	reappearance	reappearance	NN
cord-003130-p2h8p5bm	76	18	of	of	IN
cord-003130-p2h8p5bm	76	19	the	the	DT
cord-003130-p2h8p5bm	76	20	symptoms	symptom	NNS
cord-003130-p2h8p5bm	76	21	from	from	IN
cord-003130-p2h8p5bm	76	22	the	the	DT
cord-003130-p2h8p5bm	76	23	initial	initial	JJ
cord-003130-p2h8p5bm	76	24	phase	phase	NN
cord-003130-p2h8p5bm	76	25	.	.	.
cord-003130-p2h8p5bm	77	1	Case	case	NN
cord-003130-p2h8p5bm	77	2	fatality	fatality	NN
cord-003130-p2h8p5bm	77	3	rates	rate	NNS
cord-003130-p2h8p5bm	77	4	range	range	VBP
cord-003130-p2h8p5bm	77	5	from	from	IN
cord-003130-p2h8p5bm	77	6	0.5	0.5	CD
cord-003130-p2h8p5bm	77	7	to	to	TO
cord-003130-p2h8p5bm	77	8	2.5	2.5	CD
cord-003130-p2h8p5bm	77	9	%	%	NN
cord-003130-p2h8p5bm	77	10	[	[	-LRB-
cord-003130-p2h8p5bm	77	11	63	63	CD
cord-003130-p2h8p5bm	77	12	]	]	-RRB-
cord-003130-p2h8p5bm	77	13	.	.	.
cord-003130-p2h8p5bm	78	1	No	no	DT
cord-003130-p2h8p5bm	78	2	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	78	3	treatments	treatment	NNS
cord-003130-p2h8p5bm	78	4	are	be	VBP
cord-003130-p2h8p5bm	78	5	available	available	JJ
cord-003130-p2h8p5bm	78	6	against	against	IN
cord-003130-p2h8p5bm	78	7	OHFV	OHFV	NNP
cord-003130-p2h8p5bm	78	8	,	,	,
cord-003130-p2h8p5bm	78	9	instead	instead	RB
cord-003130-p2h8p5bm	78	10	treatment	treatment	NN
cord-003130-p2h8p5bm	78	11	is	be	VBZ
cord-003130-p2h8p5bm	78	12	focused	focus	VBN
cord-003130-p2h8p5bm	78	13	on	on	IN
cord-003130-p2h8p5bm	78	14	supportive	supportive	JJ
cord-003130-p2h8p5bm	78	15	care	care	NN
cord-003130-p2h8p5bm	78	16	to	to	TO
cord-003130-p2h8p5bm	78	17	minimize	minimize	VB
cord-003130-p2h8p5bm	78	18	hemorrhage	hemorrhage	NN
cord-003130-p2h8p5bm	78	19	and	and	CC
cord-003130-p2h8p5bm	78	20	other	other	JJ
cord-003130-p2h8p5bm	78	21	complications	complication	NNS
cord-003130-p2h8p5bm	78	22	[	[	-LRB-
cord-003130-p2h8p5bm	78	23	17	17	CD
cord-003130-p2h8p5bm	78	24	]	]	-RRB-
cord-003130-p2h8p5bm	78	25	.	.	.
cord-003130-p2h8p5bm	79	1	KFDV	KFDV	NNP
cord-003130-p2h8p5bm	79	2	is	be	VBZ
cord-003130-p2h8p5bm	79	3	only	only	RB
cord-003130-p2h8p5bm	79	4	found	find	VBN
cord-003130-p2h8p5bm	79	5	in	in	IN
cord-003130-p2h8p5bm	79	6	India	India	NNP
cord-003130-p2h8p5bm	79	7	(	(	-LRB-
cord-003130-p2h8p5bm	79	8	Figure	figure	NN
cord-003130-p2h8p5bm	79	9	1	1	CD
cord-003130-p2h8p5bm	79	10	)	)	-RRB-
cord-003130-p2h8p5bm	79	11	,	,	,
cord-003130-p2h8p5bm	79	12	although	although	IN
cord-003130-p2h8p5bm	79	13	a	a	DT
cord-003130-p2h8p5bm	79	14	similar	similar	JJ
cord-003130-p2h8p5bm	79	15	genetic	genetic	JJ
cord-003130-p2h8p5bm	79	16	variant	variant	NN
cord-003130-p2h8p5bm	79	17	,	,	,
cord-003130-p2h8p5bm	79	18	Alkhurma	Alkhurma	NNP
cord-003130-p2h8p5bm	79	19	hemorrhagic	hemorrhagic	JJ
cord-003130-p2h8p5bm	79	20	fever	fever	NN
cord-003130-p2h8p5bm	79	21	virus	virus	NN
cord-003130-p2h8p5bm	79	22	(	(	-LRB-
cord-003130-p2h8p5bm	79	23	AHFV	AHFV	NNP
cord-003130-p2h8p5bm	79	24	)	)	-RRB-
cord-003130-p2h8p5bm	79	25	has	have	VBZ
cord-003130-p2h8p5bm	79	26	been	be	VBN
cord-003130-p2h8p5bm	79	27	detected	detect	VBN
cord-003130-p2h8p5bm	79	28	in	in	IN
cord-003130-p2h8p5bm	79	29	Saudi	Saudi	NNP
cord-003130-p2h8p5bm	79	30	Arabia	Arabia	NNP
cord-003130-p2h8p5bm	79	31	[	[	-LRB-
cord-003130-p2h8p5bm	79	32	17	17	CD
cord-003130-p2h8p5bm	79	33	,	,	,
cord-003130-p2h8p5bm	79	34	47	47	CD
cord-003130-p2h8p5bm	79	35	]	]	-RRB-
cord-003130-p2h8p5bm	79	36	.	.	.
cord-003130-p2h8p5bm	80	1	KFDV	KFDV	NNP
cord-003130-p2h8p5bm	80	2	is	be	VBZ
cord-003130-p2h8p5bm	80	3	mainly	mainly	RB
cord-003130-p2h8p5bm	80	4	transmitted	transmit	VBN
cord-003130-p2h8p5bm	80	5	by	by	IN
cord-003130-p2h8p5bm	80	6	ticks	tick	NNS
cord-003130-p2h8p5bm	80	7	belonging	belong	VBG
cord-003130-p2h8p5bm	80	8	to	to	IN
cord-003130-p2h8p5bm	80	9	the	the	DT
cord-003130-p2h8p5bm	80	10	genus	genus	NN
cord-003130-p2h8p5bm	80	11	Hemaphysalis	Hemaphysalis	NNP
cord-003130-p2h8p5bm	80	12	but	but	CC
cord-003130-p2h8p5bm	80	13	other	other	JJ
cord-003130-p2h8p5bm	80	14	tick	tick	NN
cord-003130-p2h8p5bm	80	15	genera	genus	NNS
cord-003130-p2h8p5bm	80	16	have	have	VBP
cord-003130-p2h8p5bm	80	17	also	also	RB
cord-003130-p2h8p5bm	80	18	been	be	VBN
cord-003130-p2h8p5bm	80	19	shown	show	VBN
cord-003130-p2h8p5bm	80	20	to	to	TO
cord-003130-p2h8p5bm	80	21	be	be	VB
cord-003130-p2h8p5bm	80	22	able	able	JJ
cord-003130-p2h8p5bm	80	23	to	to	TO
cord-003130-p2h8p5bm	80	24	transmit	transmit	VB
cord-003130-p2h8p5bm	80	25	KFDV	KFDV	NNP
cord-003130-p2h8p5bm	80	26	[	[	-LRB-
cord-003130-p2h8p5bm	80	27	64	64	CD
cord-003130-p2h8p5bm	80	28	,	,	,
cord-003130-p2h8p5bm	80	29	65	65	CD
cord-003130-p2h8p5bm	80	30	]	]	-RRB-
cord-003130-p2h8p5bm	80	31	.	.	.
cord-003130-p2h8p5bm	81	1	During	during	IN
cord-003130-p2h8p5bm	81	2	hemorrhagic	hemorrhagic	JJ
cord-003130-p2h8p5bm	81	3	KFDV	KFDV	NNP
cord-003130-p2h8p5bm	81	4	infection	infection	NN
cord-003130-p2h8p5bm	81	5	,	,	,
cord-003130-p2h8p5bm	81	6	the	the	DT
cord-003130-p2h8p5bm	81	7	initial	initial	JJ
cord-003130-p2h8p5bm	81	8	phase	phase	NN
cord-003130-p2h8p5bm	81	9	is	be	VBZ
cord-003130-p2h8p5bm	81	10	similar	similar	JJ
cord-003130-p2h8p5bm	81	11	to	to	IN
cord-003130-p2h8p5bm	81	12	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	81	13	infection	infection	NN
cord-003130-p2h8p5bm	81	14	with	with	IN
cord-003130-p2h8p5bm	81	15	fever	fever	NN
cord-003130-p2h8p5bm	81	16	and	and	CC
cord-003130-p2h8p5bm	81	17	flu	flu	NN
cord-003130-p2h8p5bm	81	18	-	-	HYPH
cord-003130-p2h8p5bm	81	19	like	like	JJ
cord-003130-p2h8p5bm	81	20	symptoms	symptom	NNS
cord-003130-p2h8p5bm	81	21	,	,	,
cord-003130-p2h8p5bm	81	22	but	but	CC
cord-003130-p2h8p5bm	81	23	it	-PRON-	PRP
cord-003130-p2h8p5bm	81	24	may	may	MD
cord-003130-p2h8p5bm	81	25	also	also	RB
cord-003130-p2h8p5bm	81	26	include	include	VB
cord-003130-p2h8p5bm	81	27	bleeding	bleed	VBG
cord-003130-p2h8p5bm	81	28	from	from	IN
cord-003130-p2h8p5bm	81	29	the	the	DT
cord-003130-p2h8p5bm	81	30	nose	nose	NN
cord-003130-p2h8p5bm	81	31	,	,	,
cord-003130-p2h8p5bm	81	32	mouth	mouth	NN
cord-003130-p2h8p5bm	81	33	or	or	CC
cord-003130-p2h8p5bm	81	34	gastrointestinal	gastrointestinal	JJ
cord-003130-p2h8p5bm	81	35	tract	tract	NN
cord-003130-p2h8p5bm	81	36	[	[	-LRB-
cord-003130-p2h8p5bm	81	37	65	65	CD
cord-003130-p2h8p5bm	81	38	,	,	,
cord-003130-p2h8p5bm	81	39	66	66	CD
cord-003130-p2h8p5bm	81	40	]	]	-RRB-
cord-003130-p2h8p5bm	81	41	.	.	.
cord-003130-p2h8p5bm	82	1	The	the	DT
cord-003130-p2h8p5bm	82	2	second	second	JJ
cord-003130-p2h8p5bm	82	3	phase	phase	NN
cord-003130-p2h8p5bm	82	4	,	,	,
cord-003130-p2h8p5bm	82	5	which	which	WDT
cord-003130-p2h8p5bm	82	6	is	be	VBZ
cord-003130-p2h8p5bm	82	7	experienced	experience	VBN
cord-003130-p2h8p5bm	82	8	by	by	IN
cord-003130-p2h8p5bm	82	9	1	1	CD
cord-003130-p2h8p5bm	82	10	-	-	SYM
cord-003130-p2h8p5bm	82	11	20	20	CD
cord-003130-p2h8p5bm	82	12	%	%	NN
cord-003130-p2h8p5bm	82	13	of	of	IN
cord-003130-p2h8p5bm	82	14	the	the	DT
cord-003130-p2h8p5bm	82	15	cases	case	NNS
cord-003130-p2h8p5bm	82	16	,	,	,
cord-003130-p2h8p5bm	82	17	includes	include	VBZ
cord-003130-p2h8p5bm	82	18	neurological	neurological	JJ
cord-003130-p2h8p5bm	82	19	symptoms	symptom	NNS
cord-003130-p2h8p5bm	82	20	such	such	JJ
cord-003130-p2h8p5bm	82	21	as	as	IN
cord-003130-p2h8p5bm	82	22	headache	headache	NN
cord-003130-p2h8p5bm	82	23	,	,	,
cord-003130-p2h8p5bm	82	24	mental	mental	JJ
cord-003130-p2h8p5bm	82	25	disturbance	disturbance	NN
cord-003130-p2h8p5bm	82	26	,	,	,
cord-003130-p2h8p5bm	82	27	and	and	CC
cord-003130-p2h8p5bm	82	28	tremor	tremor	NN
cord-003130-p2h8p5bm	82	29	,	,	,
cord-003130-p2h8p5bm	82	30	however	however	RB
cord-003130-p2h8p5bm	82	31	,	,	,
cord-003130-p2h8p5bm	82	32	no	no	DT
cord-003130-p2h8p5bm	82	33	evidence	evidence	NN
cord-003130-p2h8p5bm	82	34	of	of	IN
cord-003130-p2h8p5bm	82	35	meninges	meninge	NNS
cord-003130-p2h8p5bm	82	36	or	or	CC
cord-003130-p2h8p5bm	82	37	encephalitis	encephalitis	RB
cord-003130-p2h8p5bm	82	38	have	have	VBP
cord-003130-p2h8p5bm	82	39	been	be	VBN
cord-003130-p2h8p5bm	82	40	found	find	VBN
cord-003130-p2h8p5bm	82	41	[	[	-LRB-
cord-003130-p2h8p5bm	82	42	65	65	CD
cord-003130-p2h8p5bm	82	43	]	]	-RRB-
cord-003130-p2h8p5bm	82	44	.	.	.
cord-003130-p2h8p5bm	83	1	There	there	EX
cord-003130-p2h8p5bm	83	2	are	be	VBP
cord-003130-p2h8p5bm	83	3	about	about	RB
cord-003130-p2h8p5bm	83	4	400	400	CD
cord-003130-p2h8p5bm	83	5	-	-	SYM
cord-003130-p2h8p5bm	83	6	500	500	CD
cord-003130-p2h8p5bm	83	7	reported	report	VBD
cord-003130-p2h8p5bm	83	8	annual	annual	JJ
cord-003130-p2h8p5bm	83	9	cases	case	NNS
cord-003130-p2h8p5bm	83	10	of	of	IN
cord-003130-p2h8p5bm	83	11	KFDV	KFDV	NNP
cord-003130-p2h8p5bm	83	12	[	[	-LRB-
cord-003130-p2h8p5bm	83	13	47	47	CD
cord-003130-p2h8p5bm	83	14	]	]	-RRB-
cord-003130-p2h8p5bm	83	15	,	,	,
cord-003130-p2h8p5bm	83	16	with	with	IN
cord-003130-p2h8p5bm	83	17	case	case	NN
cord-003130-p2h8p5bm	83	18	fatality	fatality	NN
cord-003130-p2h8p5bm	83	19	rates	rate	NNS
cord-003130-p2h8p5bm	83	20	ranging	range	VBG
cord-003130-p2h8p5bm	83	21	from	from	IN
cord-003130-p2h8p5bm	83	22	3	3	CD
cord-003130-p2h8p5bm	83	23	to	to	TO
cord-003130-p2h8p5bm	83	24	10	10	CD
cord-003130-p2h8p5bm	83	25	%	%	NN
cord-003130-p2h8p5bm	83	26	[	[	-LRB-
cord-003130-p2h8p5bm	83	27	17	17	CD
cord-003130-p2h8p5bm	83	28	,	,	,
cord-003130-p2h8p5bm	83	29	65	65	CD
cord-003130-p2h8p5bm	83	30	]	]	-RRB-
cord-003130-p2h8p5bm	83	31	.	.	.
cord-003130-p2h8p5bm	84	1	In	in	IN
cord-003130-p2h8p5bm	84	2	1990	1990	CD
cord-003130-p2h8p5bm	84	3	a	a	DT
cord-003130-p2h8p5bm	84	4	KFDV	KFDV	NNP
cord-003130-p2h8p5bm	84	5	vaccine	vaccine	NN
cord-003130-p2h8p5bm	84	6	was	be	VBD
cord-003130-p2h8p5bm	84	7	developed	develop	VBN
cord-003130-p2h8p5bm	84	8	,	,	,
cord-003130-p2h8p5bm	84	9	although	although	IN
cord-003130-p2h8p5bm	84	10	it	-PRON-	PRP
cord-003130-p2h8p5bm	84	11	provided	provide	VBD
cord-003130-p2h8p5bm	84	12	some	some	DT
cord-003130-p2h8p5bm	84	13	protection	protection	NN
cord-003130-p2h8p5bm	84	14	,	,	,
cord-003130-p2h8p5bm	84	15	due	due	IN
cord-003130-p2h8p5bm	84	16	to	to	IN
cord-003130-p2h8p5bm	84	17	low	low	JJ
cord-003130-p2h8p5bm	84	18	efficacy	efficacy	NN
cord-003130-p2h8p5bm	84	19	,	,	,
cord-003130-p2h8p5bm	84	20	the	the	DT
cord-003130-p2h8p5bm	84	21	number	number	NN
cord-003130-p2h8p5bm	84	22	of	of	IN
cord-003130-p2h8p5bm	84	23	cases	case	NNS
cord-003130-p2h8p5bm	84	24	still	still	RB
cord-003130-p2h8p5bm	84	25	increased	increase	VBD
cord-003130-p2h8p5bm	84	26	from	from	IN
cord-003130-p2h8p5bm	84	27	1999	1999	CD
cord-003130-p2h8p5bm	84	28	to	to	IN
cord-003130-p2h8p5bm	84	29	2012	2012	CD
cord-003130-p2h8p5bm	84	30	[	[	-LRB-
cord-003130-p2h8p5bm	84	31	67	67	CD
cord-003130-p2h8p5bm	84	32	]	]	-RRB-
cord-003130-p2h8p5bm	85	1	[	[	-LRB-
cord-003130-p2h8p5bm	85	2	68	68	CD
cord-003130-p2h8p5bm	85	3	]	]	-RRB-
cord-003130-p2h8p5bm	85	4	[	[	-LRB-
cord-003130-p2h8p5bm	85	5	69	69	CD
cord-003130-p2h8p5bm	85	6	]	]	-RRB-
cord-003130-p2h8p5bm	85	7	.	.	.
cord-003130-p2h8p5bm	86	1	Treatment	treatment	NN
cord-003130-p2h8p5bm	86	2	of	of	IN
cord-003130-p2h8p5bm	86	3	KFDV	KFDV	NNP
cord-003130-p2h8p5bm	86	4	is	be	VBZ
cord-003130-p2h8p5bm	86	5	limited	limit	VBN
cord-003130-p2h8p5bm	86	6	to	to	IN
cord-003130-p2h8p5bm	86	7	supportive	supportive	JJ
cord-003130-p2h8p5bm	86	8	care	care	NN
cord-003130-p2h8p5bm	86	9	[	[	-LRB-
cord-003130-p2h8p5bm	86	10	47	47	CD
cord-003130-p2h8p5bm	86	11	]	]	-RRB-
cord-003130-p2h8p5bm	86	12	.	.	.
cord-003130-p2h8p5bm	87	1	TBFVs	tbfv	NNS
cord-003130-p2h8p5bm	87	2	are	be	VBP
cord-003130-p2h8p5bm	87	3	enveloped	envelop	VBN
cord-003130-p2h8p5bm	87	4	viruses	virus	NNS
cord-003130-p2h8p5bm	87	5	around	around	IN
cord-003130-p2h8p5bm	87	6	50	50	CD
cord-003130-p2h8p5bm	87	7	nm	nm	NN
cord-003130-p2h8p5bm	87	8	in	in	IN
cord-003130-p2h8p5bm	87	9	diameter	diameter	NN
cord-003130-p2h8p5bm	87	10	.	.	.
cord-003130-p2h8p5bm	88	1	The	the	DT
cord-003130-p2h8p5bm	88	2	envelope	envelope	NN
cord-003130-p2h8p5bm	88	3	carries	carry	VBZ
cord-003130-p2h8p5bm	88	4	two	two	CD
cord-003130-p2h8p5bm	88	5	surface	surface	NN
cord-003130-p2h8p5bm	88	6	proteins	protein	NNS
cord-003130-p2h8p5bm	88	7	,	,	,
cord-003130-p2h8p5bm	88	8	the	the	DT
cord-003130-p2h8p5bm	88	9	envelope	envelope	NN
cord-003130-p2h8p5bm	88	10	(	(	-LRB-
cord-003130-p2h8p5bm	88	11	E	e	NN
cord-003130-p2h8p5bm	88	12	)	)	-RRB-
cord-003130-p2h8p5bm	88	13	protein	protein	NN
cord-003130-p2h8p5bm	88	14	and	and	CC
cord-003130-p2h8p5bm	88	15	the	the	DT
cord-003130-p2h8p5bm	88	16	membrane	membrane	NN
cord-003130-p2h8p5bm	88	17	(	(	-LRB-
cord-003130-p2h8p5bm	88	18	M	M	NNP
cord-003130-p2h8p5bm	88	19	)	)	-RRB-
cord-003130-p2h8p5bm	88	20	protein	protein	NN
cord-003130-p2h8p5bm	88	21	.	.	.
cord-003130-p2h8p5bm	89	1	The	the	DT
cord-003130-p2h8p5bm	89	2	latter	latter	JJ
cord-003130-p2h8p5bm	89	3	is	be	VBZ
cord-003130-p2h8p5bm	89	4	derived	derive	VBN
cord-003130-p2h8p5bm	89	5	from	from	IN
cord-003130-p2h8p5bm	89	6	a	a	DT
cord-003130-p2h8p5bm	89	7	precursor	precursor	NN
cord-003130-p2h8p5bm	89	8	protein	protein	NN
cord-003130-p2h8p5bm	89	9	,	,	,
cord-003130-p2h8p5bm	89	10	prM.	prm.	FW
cord-003130-p2h8p5bm	89	11	The	the	DT
cord-003130-p2h8p5bm	89	12	nucleocapsid	nucleocapsid	NN
cord-003130-p2h8p5bm	89	13	(	(	-LRB-
cord-003130-p2h8p5bm	89	14	NC	NC	NNP
cord-003130-p2h8p5bm	89	15	)	)	-RRB-
cord-003130-p2h8p5bm	89	16	lies	lie	VBZ
cord-003130-p2h8p5bm	89	17	inside	inside	IN
cord-003130-p2h8p5bm	89	18	the	the	DT
cord-003130-p2h8p5bm	89	19	viral	viral	JJ
cord-003130-p2h8p5bm	89	20	envelope	envelope	NN
cord-003130-p2h8p5bm	89	21	and	and	CC
cord-003130-p2h8p5bm	89	22	consists	consist	VBZ
cord-003130-p2h8p5bm	89	23	of	of	IN
cord-003130-p2h8p5bm	89	24	multiple	multiple	JJ
cord-003130-p2h8p5bm	89	25	copies	copy	NNS
cord-003130-p2h8p5bm	89	26	of	of	IN
cord-003130-p2h8p5bm	89	27	capsid	capsid	FW
cord-003130-p2h8p5bm	89	28	(	(	-LRB-
cord-003130-p2h8p5bm	89	29	C	C	NNP
cord-003130-p2h8p5bm	89	30	)	)	-RRB-
cord-003130-p2h8p5bm	89	31	protein	protein	NN
cord-003130-p2h8p5bm	89	32	and	and	CC
cord-003130-p2h8p5bm	89	33	the	the	DT
cord-003130-p2h8p5bm	89	34	viral	viral	JJ
cord-003130-p2h8p5bm	89	35	genome	genome	NN
cord-003130-p2h8p5bm	89	36	.	.	.
cord-003130-p2h8p5bm	90	1	The	the	DT
cord-003130-p2h8p5bm	90	2	TBFV	TBFV	NNP
cord-003130-p2h8p5bm	90	3	genomes	genome	NNS
cord-003130-p2h8p5bm	90	4	are	be	VBP
cord-003130-p2h8p5bm	90	5	single	single	RB
cord-003130-p2h8p5bm	90	6	stranded	stranded	JJ
cord-003130-p2h8p5bm	90	7	,	,	,
cord-003130-p2h8p5bm	90	8	positive	positive	JJ
cord-003130-p2h8p5bm	90	9	-	-	HYPH
cord-003130-p2h8p5bm	90	10	sense	sense	NN
cord-003130-p2h8p5bm	90	11	RNA	RNA	NNP
cord-003130-p2h8p5bm	90	12	of	of	IN
cord-003130-p2h8p5bm	90	13	approximately	approximately	RB
cord-003130-p2h8p5bm	90	14	11,000	11,000	CD
cord-003130-p2h8p5bm	90	15	nucleotides	nucleotide	NNS
cord-003130-p2h8p5bm	90	16	.	.	.
cord-003130-p2h8p5bm	91	1	It	-PRON-	PRP
cord-003130-p2h8p5bm	91	2	has	have	VBZ
cord-003130-p2h8p5bm	91	3	a	a	DT
cord-003130-p2h8p5bm	91	4	5	5	CD
cord-003130-p2h8p5bm	91	5	-cap	-cap	:
cord-003130-p2h8p5bm	91	6	with	with	IN
cord-003130-p2h8p5bm	91	7	a	a	DT
cord-003130-p2h8p5bm	91	8	single	single	JJ
cord-003130-p2h8p5bm	91	9	open	open	JJ
cord-003130-p2h8p5bm	91	10	reading	reading	NN
cord-003130-p2h8p5bm	91	11	frame	frame	NN
cord-003130-p2h8p5bm	91	12	(	(	-LRB-
cord-003130-p2h8p5bm	91	13	ORF	ORF	NNP
cord-003130-p2h8p5bm	91	14	)	)	-RRB-
cord-003130-p2h8p5bm	91	15	.	.	.
cord-003130-p2h8p5bm	92	1	The	the	DT
cord-003130-p2h8p5bm	92	2	ORF	ORF	NNP
cord-003130-p2h8p5bm	92	3	is	be	VBZ
cord-003130-p2h8p5bm	92	4	flanked	flank	VBN
cord-003130-p2h8p5bm	92	5	by	by	IN
cord-003130-p2h8p5bm	92	6	5	5	CD
cord-003130-p2h8p5bm	92	7	and	and	CC
cord-003130-p2h8p5bm	92	8	3	3	CD
cord-003130-p2h8p5bm	92	9	untranslated	untranslated	JJ
cord-003130-p2h8p5bm	92	10	regions	region	NNS
cord-003130-p2h8p5bm	92	11	(	(	-LRB-
cord-003130-p2h8p5bm	92	12	UTRs	UTRs	NNP
cord-003130-p2h8p5bm	92	13	)	)	-RRB-
cord-003130-p2h8p5bm	92	14	.	.	.
cord-003130-p2h8p5bm	93	1	The	the	DT
cord-003130-p2h8p5bm	93	2	viral	viral	JJ
cord-003130-p2h8p5bm	93	3	protein	protein	NN
cord-003130-p2h8p5bm	93	4	is	be	VBZ
cord-003130-p2h8p5bm	93	5	encoded	encode	VBN
cord-003130-p2h8p5bm	93	6	by	by	IN
cord-003130-p2h8p5bm	93	7	the	the	DT
cord-003130-p2h8p5bm	93	8	ORF	ORF	NNP
cord-003130-p2h8p5bm	93	9	as	as	IN
cord-003130-p2h8p5bm	93	10	a	a	DT
cord-003130-p2h8p5bm	93	11	single	single	JJ
cord-003130-p2h8p5bm	93	12	polyprotein	polyprotein	NN
cord-003130-p2h8p5bm	93	13	,	,	,
cord-003130-p2h8p5bm	93	14	which	which	WDT
cord-003130-p2h8p5bm	93	15	is	be	VBZ
cord-003130-p2h8p5bm	93	16	co	co	JJ
cord-003130-p2h8p5bm	93	17	-	-	JJ
cord-003130-p2h8p5bm	93	18	and	and	CC
cord-003130-p2h8p5bm	93	19	post	post	VB
cord-003130-p2h8p5bm	93	20	-	-	NN
cord-003130-p2h8p5bm	93	21	translationally	translationally	RB
cord-003130-p2h8p5bm	93	22	cleaved	cleave	VBN
cord-003130-p2h8p5bm	93	23	by	by	IN
cord-003130-p2h8p5bm	93	24	cellular	cellular	JJ
cord-003130-p2h8p5bm	93	25	and	and	CC
cord-003130-p2h8p5bm	93	26	viral	viral	JJ
cord-003130-p2h8p5bm	93	27	proteases	protease	NNS
cord-003130-p2h8p5bm	93	28	into	into	IN
cord-003130-p2h8p5bm	93	29	individual	individual	JJ
cord-003130-p2h8p5bm	93	30	viral	viral	JJ
cord-003130-p2h8p5bm	93	31	proteins	protein	NNS
cord-003130-p2h8p5bm	93	32	(	(	-LRB-
cord-003130-p2h8p5bm	93	33	three	three	CD
cord-003130-p2h8p5bm	93	34	structural	structural	JJ
cord-003130-p2h8p5bm	93	35	and	and	CC
cord-003130-p2h8p5bm	93	36	seven	seven	CD
cord-003130-p2h8p5bm	93	37	non	non	JJ
cord-003130-p2h8p5bm	93	38	-	-	JJ
cord-003130-p2h8p5bm	93	39	structural	structural	JJ
cord-003130-p2h8p5bm	93	40	)	)	-RRB-
cord-003130-p2h8p5bm	93	41	.	.	.
cord-003130-p2h8p5bm	94	1	The	the	DT
cord-003130-p2h8p5bm	94	2	polyprotein	polyprotein	NN
cord-003130-p2h8p5bm	94	3	is	be	VBZ
cord-003130-p2h8p5bm	94	4	arranged	arrange	VBN
cord-003130-p2h8p5bm	94	5	in	in	IN
cord-003130-p2h8p5bm	94	6	the	the	DT
cord-003130-p2h8p5bm	94	7	order	order	NN
cord-003130-p2h8p5bm	94	8	5	5	CD
cord-003130-p2h8p5bm	94	9	-C	-c	ADD
cord-003130-p2h8p5bm	95	1	-prM	-prM	NNS
cord-003130-p2h8p5bm	95	2	-	-	HYPH
cord-003130-p2h8p5bm	95	3	E	E	NNP
cord-003130-p2h8p5bm	95	4	-	-	HYPH
cord-003130-p2h8p5bm	95	5	NS1-NS2A	NS1-NS2A	NNP
cord-003130-p2h8p5bm	95	6	-	-	HYPH
cord-003130-p2h8p5bm	95	7	NS2B	NS2B	NNP
cord-003130-p2h8p5bm	95	8	-	-	HYPH
cord-003130-p2h8p5bm	95	9	NS3-NS4A-	NS3-NS4A-	NNP
cord-003130-p2h8p5bm	96	1	NS4B	NS4B	NNP
cord-003130-p2h8p5bm	96	2	-	-	HYPH
cord-003130-p2h8p5bm	96	3	NS5	ns5	JJ
cord-003130-p2h8p5bm	96	4	-	-	HYPH
cord-003130-p2h8p5bm	96	5	3	3	CD
cord-003130-p2h8p5bm	96	6	[	[	-LRB-
cord-003130-p2h8p5bm	96	7	70	70	CD
cord-003130-p2h8p5bm	96	8	,	,	,
cord-003130-p2h8p5bm	96	9	71	71	CD
cord-003130-p2h8p5bm	96	10	]	]	-RRB-
cord-003130-p2h8p5bm	96	11	.	.	.
cord-003130-p2h8p5bm	97	1	The	the	DT
cord-003130-p2h8p5bm	97	2	first	first	JJ
cord-003130-p2h8p5bm	97	3	step	step	NN
cord-003130-p2h8p5bm	97	4	of	of	IN
cord-003130-p2h8p5bm	97	5	virus	virus	NN
cord-003130-p2h8p5bm	97	6	replication	replication	NN
cord-003130-p2h8p5bm	97	7	starts	start	VBZ
cord-003130-p2h8p5bm	97	8	when	when	WRB
cord-003130-p2h8p5bm	97	9	the	the	DT
cord-003130-p2h8p5bm	97	10	virus	virus	NN
cord-003130-p2h8p5bm	97	11	binds	bind	VBZ
cord-003130-p2h8p5bm	97	12	to	to	IN
cord-003130-p2h8p5bm	97	13	its	-PRON-	PRP$
cord-003130-p2h8p5bm	97	14	receptor	receptor	NN
cord-003130-p2h8p5bm	97	15	and	and	CC
cord-003130-p2h8p5bm	97	16	is	be	VBZ
cord-003130-p2h8p5bm	97	17	taken	take	VBN
cord-003130-p2h8p5bm	97	18	up	up	RP
cord-003130-p2h8p5bm	97	19	into	into	IN
cord-003130-p2h8p5bm	97	20	the	the	DT
cord-003130-p2h8p5bm	97	21	cell	cell	NN
cord-003130-p2h8p5bm	97	22	by	by	IN
cord-003130-p2h8p5bm	97	23	receptor	receptor	NN
cord-003130-p2h8p5bm	97	24	-	-	HYPH
cord-003130-p2h8p5bm	97	25	mediated	mediate	VBN
cord-003130-p2h8p5bm	97	26	endocytosis	endocytosis	NN
cord-003130-p2h8p5bm	97	27	.	.	.
cord-003130-p2h8p5bm	98	1	The	the	DT
cord-003130-p2h8p5bm	98	2	attachment	attachment	NN
cord-003130-p2h8p5bm	98	3	is	be	VBZ
cord-003130-p2h8p5bm	98	4	mediated	mediate	VBN
cord-003130-p2h8p5bm	98	5	by	by	IN
cord-003130-p2h8p5bm	98	6	viral	viral	JJ
cord-003130-p2h8p5bm	98	7	E	e	NN
cord-003130-p2h8p5bm	98	8	protein	protein	NN
cord-003130-p2h8p5bm	98	9	and	and	CC
cord-003130-p2h8p5bm	98	10	entry	entry	NN
cord-003130-p2h8p5bm	98	11	receptor	receptor	NN
cord-003130-p2h8p5bm	98	12	on	on	IN
cord-003130-p2h8p5bm	98	13	the	the	DT
cord-003130-p2h8p5bm	98	14	host	host	NN
cord-003130-p2h8p5bm	98	15	cell	cell	NN
cord-003130-p2h8p5bm	98	16	.	.	.
cord-003130-p2h8p5bm	99	1	The	the	DT
cord-003130-p2h8p5bm	99	2	entry	entry	NN
cord-003130-p2h8p5bm	99	3	receptor	receptor	NN
cord-003130-p2h8p5bm	99	4	for	for	IN
cord-003130-p2h8p5bm	99	5	TBFVs	tbfvs	NN
cord-003130-p2h8p5bm	99	6	has	have	VBZ
cord-003130-p2h8p5bm	99	7	not	not	RB
cord-003130-p2h8p5bm	99	8	been	be	VBN
cord-003130-p2h8p5bm	99	9	identified	identify	VBN
cord-003130-p2h8p5bm	99	10	,	,	,
cord-003130-p2h8p5bm	99	11	but	but	CC
cord-003130-p2h8p5bm	99	12	attachment	attachment	NN
cord-003130-p2h8p5bm	99	13	to	to	IN
cord-003130-p2h8p5bm	99	14	heparan	heparan	NN
cord-003130-p2h8p5bm	99	15	sulphate	sulphate	NN
cord-003130-p2h8p5bm	99	16	and	and	CC
cord-003130-p2h8p5bm	99	17	glycosaminoglycan	glycosaminoglycan	NNP
cord-003130-p2h8p5bm	99	18	,	,	,
cord-003130-p2h8p5bm	99	19	which	which	WDT
cord-003130-p2h8p5bm	99	20	are	be	VBP
cord-003130-p2h8p5bm	99	21	present	present	JJ
cord-003130-p2h8p5bm	99	22	in	in	IN
cord-003130-p2h8p5bm	99	23	abundance	abundance	NN
cord-003130-p2h8p5bm	99	24	on	on	IN
cord-003130-p2h8p5bm	99	25	many	many	JJ
cord-003130-p2h8p5bm	99	26	cell	cell	NN
cord-003130-p2h8p5bm	99	27	types	type	NNS
cord-003130-p2h8p5bm	99	28	of	of	IN
cord-003130-p2h8p5bm	99	29	both	both	DT
cord-003130-p2h8p5bm	99	30	vertebrates	vertebrate	NNS
cord-003130-p2h8p5bm	99	31	and	and	CC
cord-003130-p2h8p5bm	99	32	ticks	tick	NNS
cord-003130-p2h8p5bm	99	33	,	,	,
cord-003130-p2h8p5bm	99	34	is	be	VBZ
cord-003130-p2h8p5bm	99	35	predicted	predict	VBN
cord-003130-p2h8p5bm	99	36	to	to	TO
cord-003130-p2h8p5bm	99	37	play	play	VB
cord-003130-p2h8p5bm	99	38	a	a	DT
cord-003130-p2h8p5bm	99	39	role	role	NN
cord-003130-p2h8p5bm	99	40	during	during	IN
cord-003130-p2h8p5bm	99	41	binding	binding	NN
cord-003130-p2h8p5bm	99	42	and	and	CC
cord-003130-p2h8p5bm	99	43	entry	entry	NN
cord-003130-p2h8p5bm	99	44	[	[	-LRB-
cord-003130-p2h8p5bm	99	45	72	72	CD
cord-003130-p2h8p5bm	99	46	]	]	-RRB-
cord-003130-p2h8p5bm	99	47	.	.	.
cord-003130-p2h8p5bm	100	1	Once	once	IN
cord-003130-p2h8p5bm	100	2	the	the	DT
cord-003130-p2h8p5bm	100	3	virus	virus	NN
cord-003130-p2h8p5bm	100	4	has	have	VBZ
cord-003130-p2h8p5bm	100	5	entered	enter	VBN
cord-003130-p2h8p5bm	100	6	the	the	DT
cord-003130-p2h8p5bm	100	7	cell	cell	NN
cord-003130-p2h8p5bm	100	8	,	,	,
cord-003130-p2h8p5bm	100	9	it	-PRON-	PRP
cord-003130-p2h8p5bm	100	10	is	be	VBZ
cord-003130-p2h8p5bm	100	11	transported	transport	VBN
cord-003130-p2h8p5bm	100	12	to	to	IN
cord-003130-p2h8p5bm	100	13	endosomes	endosome	NNS
cord-003130-p2h8p5bm	100	14	,	,	,
cord-003130-p2h8p5bm	100	15	where	where	WRB
cord-003130-p2h8p5bm	100	16	the	the	DT
cord-003130-p2h8p5bm	100	17	acidic	acidic	JJ
cord-003130-p2h8p5bm	100	18	environment	environment	NN
cord-003130-p2h8p5bm	100	19	of	of	IN
cord-003130-p2h8p5bm	100	20	these	these	DT
cord-003130-p2h8p5bm	100	21	vesicles	vesicle	NNS
cord-003130-p2h8p5bm	100	22	leads	lead	VBZ
cord-003130-p2h8p5bm	100	23	to	to	IN
cord-003130-p2h8p5bm	100	24	reorganization	reorganization	NN
cord-003130-p2h8p5bm	100	25	and	and	CC
cord-003130-p2h8p5bm	100	26	conformational	conformational	JJ
cord-003130-p2h8p5bm	100	27	change	change	NN
cord-003130-p2h8p5bm	100	28	of	of	IN
cord-003130-p2h8p5bm	100	29	the	the	DT
cord-003130-p2h8p5bm	100	30	E	e	NN
cord-003130-p2h8p5bm	100	31	protein	protein	NN
cord-003130-p2h8p5bm	100	32	,	,	,
cord-003130-p2h8p5bm	100	33	resulting	result	VBG
cord-003130-p2h8p5bm	100	34	in	in	IN
cord-003130-p2h8p5bm	100	35	the	the	DT
cord-003130-p2h8p5bm	100	36	fusion	fusion	NN
cord-003130-p2h8p5bm	100	37	of	of	IN
cord-003130-p2h8p5bm	100	38	the	the	DT
cord-003130-p2h8p5bm	100	39	viral	viral	JJ
cord-003130-p2h8p5bm	100	40	and	and	CC
cord-003130-p2h8p5bm	100	41	endosomal	endosomal	JJ
cord-003130-p2h8p5bm	100	42	membrane	membrane	NN
cord-003130-p2h8p5bm	100	43	and	and	CC
cord-003130-p2h8p5bm	100	44	the	the	DT
cord-003130-p2h8p5bm	100	45	release	release	NN
cord-003130-p2h8p5bm	100	46	of	of	IN
cord-003130-p2h8p5bm	100	47	the	the	DT
cord-003130-p2h8p5bm	100	48	viral	viral	JJ
cord-003130-p2h8p5bm	100	49	capsid	capsid	NN
cord-003130-p2h8p5bm	100	50	into	into	IN
cord-003130-p2h8p5bm	100	51	the	the	DT
cord-003130-p2h8p5bm	100	52	cytoplasm	cytoplasm	NN
cord-003130-p2h8p5bm	100	53	[	[	-LRB-
cord-003130-p2h8p5bm	100	54	73	73	CD
cord-003130-p2h8p5bm	100	55	]	]	-RRB-
cord-003130-p2h8p5bm	100	56	[	[	-LRB-
cord-003130-p2h8p5bm	100	57	74	74	CD
cord-003130-p2h8p5bm	100	58	]	]	-RRB-
cord-003130-p2h8p5bm	100	59	[	[	-LRB-
cord-003130-p2h8p5bm	100	60	75	75	CD
cord-003130-p2h8p5bm	100	61	]	]	-RRB-
cord-003130-p2h8p5bm	100	62	.	.	.
cord-003130-p2h8p5bm	101	1	The	the	DT
cord-003130-p2h8p5bm	101	2	viral	viral	JJ
cord-003130-p2h8p5bm	101	3	RNA	RNA	NNP
cord-003130-p2h8p5bm	101	4	(	(	-LRB-
cord-003130-p2h8p5bm	101	5	vRNA	vrna	JJ
cord-003130-p2h8p5bm	101	6	)	)	-RRB-
cord-003130-p2h8p5bm	101	7	also	also	RB
cord-003130-p2h8p5bm	101	8	functions	function	VBZ
cord-003130-p2h8p5bm	101	9	as	as	IN
cord-003130-p2h8p5bm	101	10	mRNA	mRNA	NNP
cord-003130-p2h8p5bm	101	11	,	,	,
cord-003130-p2h8p5bm	101	12	associating	associate	VBG
cord-003130-p2h8p5bm	101	13	with	with	IN
cord-003130-p2h8p5bm	101	14	ribosomes	ribosome	NNS
cord-003130-p2h8p5bm	101	15	to	to	TO
cord-003130-p2h8p5bm	101	16	produce	produce	VB
cord-003130-p2h8p5bm	101	17	the	the	DT
cord-003130-p2h8p5bm	101	18	polyprotein	polyprotein	NN
cord-003130-p2h8p5bm	101	19	.	.	.
cord-003130-p2h8p5bm	102	1	The	the	DT
cord-003130-p2h8p5bm	102	2	transmembrane	transmembrane	NN
cord-003130-p2h8p5bm	102	3	domain	domain	NN
cord-003130-p2h8p5bm	102	4	of	of	IN
cord-003130-p2h8p5bm	102	5	the	the	DT
cord-003130-p2h8p5bm	102	6	viral	viral	JJ
cord-003130-p2h8p5bm	102	7	protein	protein	NN
cord-003130-p2h8p5bm	102	8	is	be	VBZ
cord-003130-p2h8p5bm	102	9	recognized	recognize	VBN
cord-003130-p2h8p5bm	102	10	as	as	IN
cord-003130-p2h8p5bm	102	11	a	a	DT
cord-003130-p2h8p5bm	102	12	signal	signal	NN
cord-003130-p2h8p5bm	102	13	peptide	peptide	NN
cord-003130-p2h8p5bm	102	14	and	and	CC
cord-003130-p2h8p5bm	102	15	recruits	recruit	VBZ
cord-003130-p2h8p5bm	102	16	the	the	DT
cord-003130-p2h8p5bm	102	17	vRNA	vrna	JJ
cord-003130-p2h8p5bm	102	18	/	/	SYM
cord-003130-p2h8p5bm	102	19	ribosomes	ribosome	NNS
cord-003130-p2h8p5bm	102	20	/	/	SYM
cord-003130-p2h8p5bm	102	21	nascent	nascent	JJ
cord-003130-p2h8p5bm	102	22	polypeptide	polypeptide	NN
cord-003130-p2h8p5bm	102	23	complex	complex	JJ
cord-003130-p2h8p5bm	102	24	to	to	IN
cord-003130-p2h8p5bm	102	25	the	the	DT
cord-003130-p2h8p5bm	102	26	ER	ER	NNP
cord-003130-p2h8p5bm	102	27	membrane	membrane	NN
cord-003130-p2h8p5bm	102	28	,	,	,
cord-003130-p2h8p5bm	102	29	where	where	WRB
cord-003130-p2h8p5bm	102	30	it	-PRON-	PRP
cord-003130-p2h8p5bm	102	31	is	be	VBZ
cord-003130-p2h8p5bm	102	32	co	co	JJ
cord-003130-p2h8p5bm	102	33	-	-	NN
cord-003130-p2h8p5bm	102	34	translationally	translationally	RB
cord-003130-p2h8p5bm	102	35	translocated	translocate	VBN
cord-003130-p2h8p5bm	102	36	into	into	IN
cord-003130-p2h8p5bm	102	37	the	the	DT
cord-003130-p2h8p5bm	102	38	ER	ER	NNP
cord-003130-p2h8p5bm	102	39	membrane	membrane	NN
cord-003130-p2h8p5bm	102	40	[	[	-LRB-
cord-003130-p2h8p5bm	102	41	76	76	CD
cord-003130-p2h8p5bm	102	42	,	,	,
cord-003130-p2h8p5bm	102	43	77	77	CD
cord-003130-p2h8p5bm	102	44	]	]	-RRB-
cord-003130-p2h8p5bm	102	45	.	.	.
cord-003130-p2h8p5bm	103	1	The	the	DT
cord-003130-p2h8p5bm	103	2	nascent	nascent	JJ
cord-003130-p2h8p5bm	103	3	polypeptide	polypeptide	NN
cord-003130-p2h8p5bm	103	4	is	be	VBZ
cord-003130-p2h8p5bm	103	5	then	then	RB
cord-003130-p2h8p5bm	103	6	processed	process	VBN
cord-003130-p2h8p5bm	103	7	by	by	IN
cord-003130-p2h8p5bm	103	8	the	the	DT
cord-003130-p2h8p5bm	103	9	cellular	cellular	JJ
cord-003130-p2h8p5bm	103	10	and	and	CC
cord-003130-p2h8p5bm	103	11	viral	viral	JJ
cord-003130-p2h8p5bm	103	12	proteases	protease	NNS
cord-003130-p2h8p5bm	103	13	into	into	IN
cord-003130-p2h8p5bm	103	14	structural	structural	JJ
cord-003130-p2h8p5bm	103	15	and	and	CC
cord-003130-p2h8p5bm	103	16	non	non	JJ
cord-003130-p2h8p5bm	103	17	-	-	JJ
cord-003130-p2h8p5bm	103	18	structural	structural	JJ
cord-003130-p2h8p5bm	103	19	(	(	-LRB-
cord-003130-p2h8p5bm	103	20	NS	NS	NNP
cord-003130-p2h8p5bm	103	21	)	)	-RRB-
cord-003130-p2h8p5bm	103	22	viral	viral	JJ
cord-003130-p2h8p5bm	103	23	proteins	protein	NNS
cord-003130-p2h8p5bm	103	24	.	.	.
cord-003130-p2h8p5bm	104	1	Some	some	DT
cord-003130-p2h8p5bm	104	2	of	of	IN
cord-003130-p2h8p5bm	104	3	the	the	DT
cord-003130-p2h8p5bm	104	4	viral	viral	JJ
cord-003130-p2h8p5bm	104	5	proteins	protein	NNS
cord-003130-p2h8p5bm	104	6	such	such	JJ
cord-003130-p2h8p5bm	104	7	as	as	IN
cord-003130-p2h8p5bm	104	8	NS2B	NS2B	NNP
cord-003130-p2h8p5bm	104	9	,	,	,
cord-003130-p2h8p5bm	104	10	NS4A	NS4A	NNP
cord-003130-p2h8p5bm	104	11	,	,	,
cord-003130-p2h8p5bm	104	12	and	and	CC
cord-003130-p2h8p5bm	104	13	NS4B	NS4B	NNP
cord-003130-p2h8p5bm	104	14	integrate	integrate	VB
cord-003130-p2h8p5bm	104	15	and	and	CC
cord-003130-p2h8p5bm	104	16	alter	alter	VB
cord-003130-p2h8p5bm	104	17	the	the	DT
cord-003130-p2h8p5bm	104	18	membrane	membrane	NN
cord-003130-p2h8p5bm	104	19	of	of	IN
cord-003130-p2h8p5bm	104	20	the	the	DT
cord-003130-p2h8p5bm	104	21	ER	ER	NNP
cord-003130-p2h8p5bm	104	22	to	to	TO
cord-003130-p2h8p5bm	104	23	form	form	VB
cord-003130-p2h8p5bm	104	24	a	a	DT
cord-003130-p2h8p5bm	104	25	membrane	membrane	NN
cord-003130-p2h8p5bm	104	26	vesicular	vesicular	JJ
cord-003130-p2h8p5bm	104	27	structure	structure	NN
cord-003130-p2h8p5bm	104	28	,	,	,
cord-003130-p2h8p5bm	104	29	with	with	IN
cord-003130-p2h8p5bm	104	30	a	a	DT
cord-003130-p2h8p5bm	104	31	small	small	JJ
cord-003130-p2h8p5bm	104	32	pore	pore	NN
cord-003130-p2h8p5bm	104	33	connecting	connect	VBG
cord-003130-p2h8p5bm	104	34	the	the	DT
cord-003130-p2h8p5bm	104	35	interior	interior	NN
cord-003130-p2h8p5bm	104	36	of	of	IN
cord-003130-p2h8p5bm	104	37	the	the	DT
cord-003130-p2h8p5bm	104	38	vesicle	vesicle	NN
cord-003130-p2h8p5bm	104	39	to	to	IN
cord-003130-p2h8p5bm	104	40	the	the	DT
cord-003130-p2h8p5bm	104	41	cytoplasm	cytoplasm	NN
cord-003130-p2h8p5bm	104	42	[	[	-LRB-
cord-003130-p2h8p5bm	104	43	78	78	CD
cord-003130-p2h8p5bm	104	44	]	]	-RRB-
cord-003130-p2h8p5bm	104	45	[	[	-LRB-
cord-003130-p2h8p5bm	104	46	79	79	CD
cord-003130-p2h8p5bm	104	47	]	]	-RRB-
cord-003130-p2h8p5bm	105	1	[	[	-LRB-
cord-003130-p2h8p5bm	105	2	80	80	CD
cord-003130-p2h8p5bm	105	3	]	]	-RRB-
cord-003130-p2h8p5bm	106	1	[	[	-LRB-
cord-003130-p2h8p5bm	106	2	81	81	CD
cord-003130-p2h8p5bm	106	3	]	]	-RRB-
cord-003130-p2h8p5bm	106	4	[	[	-LRB-
cord-003130-p2h8p5bm	106	5	82	82	CD
cord-003130-p2h8p5bm	106	6	]	]	-RRB-
cord-003130-p2h8p5bm	106	7	.	.	.
cord-003130-p2h8p5bm	107	1	These	these	DT
cord-003130-p2h8p5bm	107	2	vesicles	vesicle	NNS
cord-003130-p2h8p5bm	107	3	are	be	VBP
cord-003130-p2h8p5bm	107	4	the	the	DT
cord-003130-p2h8p5bm	107	5	site	site	NN
cord-003130-p2h8p5bm	107	6	for	for	IN
cord-003130-p2h8p5bm	107	7	the	the	DT
cord-003130-p2h8p5bm	107	8	formation	formation	NN
cord-003130-p2h8p5bm	107	9	of	of	IN
cord-003130-p2h8p5bm	107	10	replication	replication	NN
cord-003130-p2h8p5bm	107	11	complexes	complex	NNS
cord-003130-p2h8p5bm	107	12	(	(	-LRB-
cord-003130-p2h8p5bm	107	13	RC	RC	NNP
cord-003130-p2h8p5bm	107	14	)	)	-RRB-
cord-003130-p2h8p5bm	107	15	and	and	CC
cord-003130-p2h8p5bm	107	16	RNA	RNA	NNP
cord-003130-p2h8p5bm	107	17	replication	replication	NN
cord-003130-p2h8p5bm	107	18	[	[	-LRB-
cord-003130-p2h8p5bm	107	19	80	80	CD
cord-003130-p2h8p5bm	107	20	,	,	,
cord-003130-p2h8p5bm	107	21	82	82	CD
cord-003130-p2h8p5bm	107	22	,	,	,
cord-003130-p2h8p5bm	107	23	83	83	CD
cord-003130-p2h8p5bm	107	24	]	]	-RRB-
cord-003130-p2h8p5bm	107	25	.	.	.
cord-003130-p2h8p5bm	108	1	Following	follow	VBG
cord-003130-p2h8p5bm	108	2	RNA	RNA	NNP
cord-003130-p2h8p5bm	108	3	replication	replication	NN
cord-003130-p2h8p5bm	108	4	,	,	,
cord-003130-p2h8p5bm	108	5	genomic	genomic	JJ
cord-003130-p2h8p5bm	108	6	RNA	RNA	NNP
cord-003130-p2h8p5bm	108	7	is	be	VBZ
cord-003130-p2h8p5bm	108	8	proposed	propose	VBN
cord-003130-p2h8p5bm	108	9	to	to	TO
cord-003130-p2h8p5bm	108	10	exit	exit	VB
cord-003130-p2h8p5bm	108	11	the	the	DT
cord-003130-p2h8p5bm	108	12	vesicle	vesicle	NN
cord-003130-p2h8p5bm	108	13	through	through	IN
cord-003130-p2h8p5bm	108	14	the	the	DT
cord-003130-p2h8p5bm	108	15	vesicular	vesicular	JJ
cord-003130-p2h8p5bm	108	16	pore	pore	NN
cord-003130-p2h8p5bm	108	17	and	and	CC
cord-003130-p2h8p5bm	108	18	is	be	VBZ
cord-003130-p2h8p5bm	108	19	packaged	package	VBN
cord-003130-p2h8p5bm	108	20	by	by	IN
cord-003130-p2h8p5bm	108	21	C	c	NN
cord-003130-p2h8p5bm	108	22	proteins	protein	NNS
cord-003130-p2h8p5bm	108	23	into	into	IN
cord-003130-p2h8p5bm	108	24	the	the	DT
cord-003130-p2h8p5bm	108	25	NC	NC	NNP
cord-003130-p2h8p5bm	108	26	on	on	IN
cord-003130-p2h8p5bm	108	27	the	the	DT
cord-003130-p2h8p5bm	108	28	cytoplasmic	cytoplasmic	JJ
cord-003130-p2h8p5bm	108	29	side	side	NN
cord-003130-p2h8p5bm	108	30	of	of	IN
cord-003130-p2h8p5bm	108	31	the	the	DT
cord-003130-p2h8p5bm	108	32	ER	ER	NNP
cord-003130-p2h8p5bm	108	33	membrane	membrane	NN
cord-003130-p2h8p5bm	108	34	[	[	-LRB-
cord-003130-p2h8p5bm	108	35	82	82	CD
cord-003130-p2h8p5bm	108	36	,	,	,
cord-003130-p2h8p5bm	108	37	84	84	CD
cord-003130-p2h8p5bm	108	38	,	,	,
cord-003130-p2h8p5bm	108	39	85	85	CD
cord-003130-p2h8p5bm	108	40	]	]	-RRB-
cord-003130-p2h8p5bm	108	41	.	.	.
cord-003130-p2h8p5bm	109	1	During	during	IN
cord-003130-p2h8p5bm	109	2	the	the	DT
cord-003130-p2h8p5bm	109	3	process	process	NN
cord-003130-p2h8p5bm	109	4	of	of	IN
cord-003130-p2h8p5bm	109	5	budding	bud	VBG
cord-003130-p2h8p5bm	109	6	of	of	IN
cord-003130-p2h8p5bm	109	7	NC	NC	NNP
cord-003130-p2h8p5bm	109	8	from	from	IN
cord-003130-p2h8p5bm	109	9	the	the	DT
cord-003130-p2h8p5bm	109	10	cytoplasm	cytoplasm	NN
cord-003130-p2h8p5bm	109	11	into	into	IN
cord-003130-p2h8p5bm	109	12	the	the	DT
cord-003130-p2h8p5bm	109	13	ER	ER	NNP
cord-003130-p2h8p5bm	109	14	,	,	,
cord-003130-p2h8p5bm	109	15	it	-PRON-	PRP
cord-003130-p2h8p5bm	109	16	acquires	acquire	VBZ
cord-003130-p2h8p5bm	109	17	the	the	DT
cord-003130-p2h8p5bm	109	18	lipid	lipid	NN
cord-003130-p2h8p5bm	109	19	envelope	envelope	NN
cord-003130-p2h8p5bm	109	20	along	along	IN
cord-003130-p2h8p5bm	109	21	with	with	IN
cord-003130-p2h8p5bm	109	22	E	E	NNP
cord-003130-p2h8p5bm	109	23	and	and	CC
cord-003130-p2h8p5bm	109	24	prM	prm	JJ
cord-003130-p2h8p5bm	109	25	proteins	protein	NNS
cord-003130-p2h8p5bm	109	26	,	,	,
cord-003130-p2h8p5bm	109	27	which	which	WDT
cord-003130-p2h8p5bm	109	28	are	be	VBP
cord-003130-p2h8p5bm	109	29	associated	associate	VBN
cord-003130-p2h8p5bm	109	30	with	with	IN
cord-003130-p2h8p5bm	109	31	the	the	DT
cord-003130-p2h8p5bm	109	32	ER	ER	NNP
cord-003130-p2h8p5bm	109	33	membrane	membrane	NN
cord-003130-p2h8p5bm	109	34	.	.	.
cord-003130-p2h8p5bm	110	1	The	the	DT
cord-003130-p2h8p5bm	110	2	mechanism	mechanism	NN
cord-003130-p2h8p5bm	110	3	that	that	WDT
cord-003130-p2h8p5bm	110	4	ensures	ensure	VBZ
cord-003130-p2h8p5bm	110	5	efficient	efficient	JJ
cord-003130-p2h8p5bm	110	6	incorporation	incorporation	NN
cord-003130-p2h8p5bm	110	7	of	of	IN
cord-003130-p2h8p5bm	110	8	NC	NC	NNP
cord-003130-p2h8p5bm	110	9	into	into	IN
cord-003130-p2h8p5bm	110	10	the	the	DT
cord-003130-p2h8p5bm	110	11	ER	ER	NNP
cord-003130-p2h8p5bm	110	12	membrane	membrane	NN
cord-003130-p2h8p5bm	110	13	with	with	IN
cord-003130-p2h8p5bm	110	14	the	the	DT
cord-003130-p2h8p5bm	110	15	E	e	NN
cord-003130-p2h8p5bm	110	16	and	and	CC
cord-003130-p2h8p5bm	110	17	prM	prm	JJ
cord-003130-p2h8p5bm	110	18	protein	protein	NN
cord-003130-p2h8p5bm	110	19	is	be	VBZ
cord-003130-p2h8p5bm	110	20	poorly	poorly	RB
cord-003130-p2h8p5bm	110	21	understood	understand	VBN
cord-003130-p2h8p5bm	110	22	.	.	.
cord-003130-p2h8p5bm	111	1	Following	follow	VBG
cord-003130-p2h8p5bm	111	2	budding	bud	VBG
cord-003130-p2h8p5bm	111	3	into	into	IN
cord-003130-p2h8p5bm	111	4	the	the	DT
cord-003130-p2h8p5bm	111	5	ER	ER	NNP
cord-003130-p2h8p5bm	111	6	lumen	lumen	NN
cord-003130-p2h8p5bm	111	7	,	,	,
cord-003130-p2h8p5bm	111	8	the	the	DT
cord-003130-p2h8p5bm	111	9	immature	immature	JJ
cord-003130-p2h8p5bm	111	10	virions	virion	NNS
cord-003130-p2h8p5bm	111	11	are	be	VBP
cord-003130-p2h8p5bm	111	12	transported	transport	VBN
cord-003130-p2h8p5bm	111	13	through	through	IN
cord-003130-p2h8p5bm	111	14	the	the	DT
cord-003130-p2h8p5bm	111	15	cellular	cellular	JJ
cord-003130-p2h8p5bm	111	16	secretory	secretory	JJ
cord-003130-p2h8p5bm	111	17	pathways	pathway	NNS
cord-003130-p2h8p5bm	111	18	in	in	IN
cord-003130-p2h8p5bm	111	19	a	a	DT
cord-003130-p2h8p5bm	111	20	COPI	COPI	NNP
cord-003130-p2h8p5bm	111	21	and	and	CC
cord-003130-p2h8p5bm	111	22	COPII	COPII	NNP
cord-003130-p2h8p5bm	111	23	dependent	dependent	JJ
cord-003130-p2h8p5bm	111	24	manner	manner	NN
cord-003130-p2h8p5bm	111	25	[	[	-LRB-
cord-003130-p2h8p5bm	111	26	86	86	CD
cord-003130-p2h8p5bm	111	27	]	]	-RRB-
cord-003130-p2h8p5bm	111	28	to	to	IN
cord-003130-p2h8p5bm	111	29	the	the	DT
cord-003130-p2h8p5bm	111	30	extracellular	extracellular	JJ
cord-003130-p2h8p5bm	111	31	medium	medium	NN
cord-003130-p2h8p5bm	111	32	.	.	.
cord-003130-p2h8p5bm	112	1	The	the	DT
cord-003130-p2h8p5bm	112	2	immature	immature	JJ
cord-003130-p2h8p5bm	112	3	virion	virion	NN
cord-003130-p2h8p5bm	112	4	has	have	VBZ
cord-003130-p2h8p5bm	112	5	heterodimers	heterodimer	NNS
cord-003130-p2h8p5bm	112	6	of	of	IN
cord-003130-p2h8p5bm	112	7	E	E	NNP
cord-003130-p2h8p5bm	112	8	and	and	CC
cord-003130-p2h8p5bm	112	9	prM	prm	JJ
cord-003130-p2h8p5bm	112	10	that	that	WDT
cord-003130-p2h8p5bm	112	11	completely	completely	RB
cord-003130-p2h8p5bm	112	12	cover	cover	VBP
cord-003130-p2h8p5bm	112	13	the	the	DT
cord-003130-p2h8p5bm	112	14	lipid	lipid	NN
cord-003130-p2h8p5bm	112	15	bilayer	bilayer	NN
cord-003130-p2h8p5bm	112	16	to	to	TO
cord-003130-p2h8p5bm	112	17	form	form	VB
cord-003130-p2h8p5bm	112	18	a	a	DT
cord-003130-p2h8p5bm	112	19	spiky	spiky	JJ
cord-003130-p2h8p5bm	112	20	proteinaceous	proteinaceous	JJ
cord-003130-p2h8p5bm	112	21	coat	coat	NN
cord-003130-p2h8p5bm	112	22	.	.	.
cord-003130-p2h8p5bm	113	1	During	during	IN
cord-003130-p2h8p5bm	113	2	the	the	DT
cord-003130-p2h8p5bm	113	3	transport	transport	NN
cord-003130-p2h8p5bm	113	4	through	through	IN
cord-003130-p2h8p5bm	113	5	the	the	DT
cord-003130-p2h8p5bm	113	6	Golgi	Golgi	NNP
cord-003130-p2h8p5bm	113	7	,	,	,
cord-003130-p2h8p5bm	113	8	the	the	DT
cord-003130-p2h8p5bm	113	9	E	e	NN
cord-003130-p2h8p5bm	113	10	protein	protein	NN
cord-003130-p2h8p5bm	113	11	is	be	VBZ
cord-003130-p2h8p5bm	113	12	glycosylated	glycosylate	VBN
cord-003130-p2h8p5bm	113	13	[	[	-LRB-
cord-003130-p2h8p5bm	113	14	87	87	CD
cord-003130-p2h8p5bm	113	15	]	]	-RRB-
cord-003130-p2h8p5bm	113	16	.	.	.
cord-003130-p2h8p5bm	114	1	The	the	DT
cord-003130-p2h8p5bm	114	2	acidic	acidic	JJ
cord-003130-p2h8p5bm	114	3	environment	environment	NN
cord-003130-p2h8p5bm	114	4	of	of	IN
cord-003130-p2h8p5bm	114	5	the	the	DT
cord-003130-p2h8p5bm	114	6	Golgi	Golgi	NNP
cord-003130-p2h8p5bm	114	7	induces	induce	VBZ
cord-003130-p2h8p5bm	114	8	conformational	conformational	JJ
cord-003130-p2h8p5bm	114	9	changes	change	NNS
cord-003130-p2h8p5bm	114	10	in	in	IN
cord-003130-p2h8p5bm	114	11	the	the	DT
cord-003130-p2h8p5bm	114	12	E	e	NN
cord-003130-p2h8p5bm	114	13	and	and	CC
cord-003130-p2h8p5bm	114	14	prM	prm	JJ
cord-003130-p2h8p5bm	114	15	proteins	protein	NNS
cord-003130-p2h8p5bm	114	16	,	,	,
cord-003130-p2h8p5bm	114	17	which	which	WDT
cord-003130-p2h8p5bm	114	18	exposes	expose	VBZ
cord-003130-p2h8p5bm	114	19	a	a	DT
cord-003130-p2h8p5bm	114	20	cleavage	cleavage	NN
cord-003130-p2h8p5bm	114	21	site	site	NN
cord-003130-p2h8p5bm	114	22	on	on	IN
cord-003130-p2h8p5bm	114	23	prM.	prM.	HYPH
cord-003130-p2h8p5bm	114	24	Cleavage	cleavage	NN
cord-003130-p2h8p5bm	114	25	of	of	IN
cord-003130-p2h8p5bm	114	26	prM	prm	JJ
cord-003130-p2h8p5bm	114	27	by	by	IN
cord-003130-p2h8p5bm	114	28	the	the	DT
cord-003130-p2h8p5bm	114	29	cellular	cellular	JJ
cord-003130-p2h8p5bm	114	30	protease	protease	NN
cord-003130-p2h8p5bm	114	31	furin	furin	NN
cord-003130-p2h8p5bm	114	32	results	result	NNS
cord-003130-p2h8p5bm	114	33	in	in	IN
cord-003130-p2h8p5bm	114	34	the	the	DT
cord-003130-p2h8p5bm	114	35	formation	formation	NN
cord-003130-p2h8p5bm	114	36	of	of	IN
cord-003130-p2h8p5bm	114	37	a	a	DT
cord-003130-p2h8p5bm	114	38	mature	mature	JJ
cord-003130-p2h8p5bm	114	39	virion	virion	NN
cord-003130-p2h8p5bm	114	40	[	[	-LRB-
cord-003130-p2h8p5bm	114	41	88	88	CD
cord-003130-p2h8p5bm	114	42	,	,	,
cord-003130-p2h8p5bm	114	43	89	89	CD
cord-003130-p2h8p5bm	114	44	]	]	-RRB-
cord-003130-p2h8p5bm	114	45	.	.	.
cord-003130-p2h8p5bm	115	1	Mature	mature	JJ
cord-003130-p2h8p5bm	115	2	virions	virion	NNS
cord-003130-p2h8p5bm	115	3	are	be	VBP
cord-003130-p2h8p5bm	115	4	then	then	RB
cord-003130-p2h8p5bm	115	5	released	release	VBN
cord-003130-p2h8p5bm	115	6	by	by	IN
cord-003130-p2h8p5bm	115	7	exocytosis	exocytosis	NN
cord-003130-p2h8p5bm	115	8	,	,	,
cord-003130-p2h8p5bm	115	9	which	which	WDT
cord-003130-p2h8p5bm	115	10	completes	complete	VBZ
cord-003130-p2h8p5bm	115	11	the	the	DT
cord-003130-p2h8p5bm	115	12	viral	viral	JJ
cord-003130-p2h8p5bm	115	13	life	life	NN
cord-003130-p2h8p5bm	115	14	cycle	cycle	NN
cord-003130-p2h8p5bm	115	15	[	[	-LRB-
cord-003130-p2h8p5bm	115	16	90	90	CD
cord-003130-p2h8p5bm	115	17	]	]	-RRB-
cord-003130-p2h8p5bm	115	18	[	[	-LRB-
cord-003130-p2h8p5bm	115	19	91	91	CD
cord-003130-p2h8p5bm	115	20	]	]	-RRB-
cord-003130-p2h8p5bm	115	21	[	[	-LRB-
cord-003130-p2h8p5bm	115	22	92	92	CD
cord-003130-p2h8p5bm	115	23	]	]	-RRB-
cord-003130-p2h8p5bm	116	1	(	(	-LRB-
cord-003130-p2h8p5bm	116	2	Figure	figure	NN
cord-003130-p2h8p5bm	116	3	2	2	CD
cord-003130-p2h8p5bm	116	4	)	)	-RRB-
cord-003130-p2h8p5bm	116	5	.	.	.
cord-003130-p2h8p5bm	116	6	 	 	_SP
cord-003130-p2h8p5bm	117	1	In	in	IN
cord-003130-p2h8p5bm	117	2	arthropods	arthropod	NNS
cord-003130-p2h8p5bm	117	3	,	,	,
cord-003130-p2h8p5bm	117	4	such	such	JJ
cord-003130-p2h8p5bm	117	5	as	as	IN
cord-003130-p2h8p5bm	117	6	mosquitos	mosquitos	NN
cord-003130-p2h8p5bm	117	7	and	and	CC
cord-003130-p2h8p5bm	117	8	ticks	tick	NNS
cord-003130-p2h8p5bm	117	9	,	,	,
cord-003130-p2h8p5bm	117	10	RNA	RNA	NNP
cord-003130-p2h8p5bm	117	11	interferences	interference	NNS
cord-003130-p2h8p5bm	117	12	(	(	-LRB-
cord-003130-p2h8p5bm	117	13	RNAi	RNAi	NNP
cord-003130-p2h8p5bm	117	14	)	)	-RRB-
cord-003130-p2h8p5bm	117	15	are	be	VBP
cord-003130-p2h8p5bm	117	16	the	the	DT
cord-003130-p2h8p5bm	117	17	most	most	RBS
cord-003130-p2h8p5bm	117	18	important	important	JJ
cord-003130-p2h8p5bm	117	19	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	117	20	defense	defense	NN
cord-003130-p2h8p5bm	117	21	and	and	CC
cord-003130-p2h8p5bm	117	22	tick	tick	NN
cord-003130-p2h8p5bm	117	23	cells	cell	NNS
cord-003130-p2h8p5bm	117	24	have	have	VBP
cord-003130-p2h8p5bm	117	25	been	be	VBN
cord-003130-p2h8p5bm	117	26	shown	show	VBN
cord-003130-p2h8p5bm	117	27	to	to	TO
cord-003130-p2h8p5bm	117	28	mount	mount	NNP
cord-003130-p2h8p5bm	117	29	RNAi	RNAi	NNP
cord-003130-p2h8p5bm	117	30	responses	response	NNS
cord-003130-p2h8p5bm	117	31	against	against	IN
cord-003130-p2h8p5bm	117	32	LGTV	LGTV	NNP
cord-003130-p2h8p5bm	117	33	and	and	CC
cord-003130-p2h8p5bm	117	34	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	117	35	[	[	-LRB-
cord-003130-p2h8p5bm	117	36	93	93	CD
cord-003130-p2h8p5bm	117	37	]	]	-RRB-
cord-003130-p2h8p5bm	117	38	.	.	.
cord-003130-p2h8p5bm	118	1	Proteins	protein	NNS
cord-003130-p2h8p5bm	118	2	involved	involve	VBN
cord-003130-p2h8p5bm	118	3	in	in	IN
cord-003130-p2h8p5bm	118	4	the	the	DT
cord-003130-p2h8p5bm	118	5	RNAi	RNAi	NNS
cord-003130-p2h8p5bm	118	6	mediated	mediate	VBD
cord-003130-p2h8p5bm	118	7	response	response	NN
cord-003130-p2h8p5bm	118	8	such	such	JJ
cord-003130-p2h8p5bm	118	9	as	as	IN
cord-003130-p2h8p5bm	118	10	Argonaute	Argonaute	NNP
cord-003130-p2h8p5bm	118	11	30	30	CD
cord-003130-p2h8p5bm	118	12	(	(	-LRB-
cord-003130-p2h8p5bm	118	13	Ago30	Ago30	NNP
cord-003130-p2h8p5bm	118	14	)	)	-RRB-
cord-003130-p2h8p5bm	118	15	,	,	.
cord-003130-p2h8p5bm	118	16	Ago	ago	RB
cord-003130-p2h8p5bm	118	17	16	16	CD
cord-003130-p2h8p5bm	118	18	and	and	CC
cord-003130-p2h8p5bm	118	19	Dicer	Dicer	NNP
cord-003130-p2h8p5bm	118	20	(	(	-LRB-
cord-003130-p2h8p5bm	118	21	Dcr	Dcr	NNP
cord-003130-p2h8p5bm	118	22	)	)	-RRB-
cord-003130-p2h8p5bm	118	23	90	90	CD
cord-003130-p2h8p5bm	118	24	were	be	VBD
cord-003130-p2h8p5bm	118	25	subsequently	subsequently	RB
cord-003130-p2h8p5bm	118	26	identified	identify	VBN
cord-003130-p2h8p5bm	118	27	as	as	IN
cord-003130-p2h8p5bm	118	28	inhibitors	inhibitor	NNS
cord-003130-p2h8p5bm	118	29	of	of	IN
cord-003130-p2h8p5bm	118	30	LGTV	LGTV	NNP
cord-003130-p2h8p5bm	118	31	[	[	-LRB-
cord-003130-p2h8p5bm	118	32	93	93	CD
cord-003130-p2h8p5bm	118	33	]	]	-RRB-
cord-003130-p2h8p5bm	118	34	.	.	.
cord-003130-p2h8p5bm	119	1	Furthermore	furthermore	RB
cord-003130-p2h8p5bm	119	2	RNA	RNA	NNP
cord-003130-p2h8p5bm	119	3	-	-	HYPH
cord-003130-p2h8p5bm	119	4	seq	seq	NNP
cord-003130-p2h8p5bm	119	5	and	and	CC
cord-003130-p2h8p5bm	119	6	mass	mass	NNP
cord-003130-p2h8p5bm	119	7	spectrometric	spectrometric	NNP
cord-003130-p2h8p5bm	119	8	analysis	analysis	NN
cord-003130-p2h8p5bm	119	9	revealed	reveal	VBD
cord-003130-p2h8p5bm	119	10	that	that	IN
cord-003130-p2h8p5bm	119	11	when	when	WRB
cord-003130-p2h8p5bm	119	12	challenged	challenge	VBN
cord-003130-p2h8p5bm	119	13	by	by	IN
cord-003130-p2h8p5bm	119	14	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	119	15	infection	infection	NN
cord-003130-p2h8p5bm	119	16	,	,	,
cord-003130-p2h8p5bm	119	17	tick	tick	NN
cord-003130-p2h8p5bm	119	18	cells	cell	NNS
cord-003130-p2h8p5bm	119	19	upregulated	upregulate	VBN
cord-003130-p2h8p5bm	119	20	genes	gene	NNS
cord-003130-p2h8p5bm	119	21	involved	involve	VBN
cord-003130-p2h8p5bm	119	22	in	in	IN
cord-003130-p2h8p5bm	119	23	immunity	immunity	NN
cord-003130-p2h8p5bm	119	24	and	and	CC
cord-003130-p2h8p5bm	119	25	metabolism	metabolism	NN
cord-003130-p2h8p5bm	119	26	,	,	,
cord-003130-p2h8p5bm	119	27	whereas	whereas	IN
cord-003130-p2h8p5bm	119	28	genes	gene	NNS
cord-003130-p2h8p5bm	119	29	involved	involve	VBN
cord-003130-p2h8p5bm	119	30	in	in	IN
cord-003130-p2h8p5bm	119	31	cellular	cellular	JJ
cord-003130-p2h8p5bm	119	32	stress	stress	NN
cord-003130-p2h8p5bm	119	33	were	be	VBD
cord-003130-p2h8p5bm	119	34	downregulated	downregulate	VBN
cord-003130-p2h8p5bm	119	35	[	[	-LRB-
cord-003130-p2h8p5bm	119	36	94	94	CD
cord-003130-p2h8p5bm	119	37	]	]	-RRB-
cord-003130-p2h8p5bm	119	38	.	.	.
cord-003130-p2h8p5bm	120	1	Using	use	VBG
cord-003130-p2h8p5bm	120	2	gene	gene	NN
cord-003130-p2h8p5bm	120	3	silencing	silencing	NN
cord-003130-p2h8p5bm	120	4	approaches	approach	NNS
cord-003130-p2h8p5bm	120	5	,	,	,
cord-003130-p2h8p5bm	120	6	this	this	DT
cord-003130-p2h8p5bm	120	7	study	study	NN
cord-003130-p2h8p5bm	120	8	confirmed	confirm	VBD
cord-003130-p2h8p5bm	120	9	the	the	DT
cord-003130-p2h8p5bm	120	10	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	120	11	effect	effect	NN
cord-003130-p2h8p5bm	120	12	of	of	IN
cord-003130-p2h8p5bm	120	13	Ago	Ago	NNP
cord-003130-p2h8p5bm	120	14	30	30	CD
cord-003130-p2h8p5bm	120	15	and	and	CC
cord-003130-p2h8p5bm	120	16	Dcr	Dcr	NNP
cord-003130-p2h8p5bm	120	17	90	90	CD
cord-003130-p2h8p5bm	120	18	in	in	IN
cord-003130-p2h8p5bm	120	19	tick	tick	NN
cord-003130-p2h8p5bm	120	20	cells	cell	NNS
cord-003130-p2h8p5bm	120	21	.	.	.
cord-003130-p2h8p5bm	121	1	Furthermore	furthermore	RB
cord-003130-p2h8p5bm	121	2	,	,	,
cord-003130-p2h8p5bm	121	3	novel	novel	JJ
cord-003130-p2h8p5bm	121	4	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	121	5	genes	gene	NNS
cord-003130-p2h8p5bm	121	6	such	such	JJ
cord-003130-p2h8p5bm	121	7	as	as	IN
cord-003130-p2h8p5bm	121	8	complement	complement	NN
cord-003130-p2h8p5bm	121	9	factor	factor	NN
cord-003130-p2h8p5bm	121	10	H	h	NN
cord-003130-p2h8p5bm	121	11	,	,	,
cord-003130-p2h8p5bm	121	12	heat	heat	NN
cord-003130-p2h8p5bm	121	13	shock	shock	NN
cord-003130-p2h8p5bm	121	14	protein	protein	NN
cord-003130-p2h8p5bm	121	15	(	(	-LRB-
cord-003130-p2h8p5bm	121	16	HSP	HSP	NNP
cord-003130-p2h8p5bm	121	17	)	)	-RRB-
cord-003130-p2h8p5bm	121	18	70	70	CD
cord-003130-p2h8p5bm	121	19	and	and	CC
cord-003130-p2h8p5bm	121	20	90	90	CD
cord-003130-p2h8p5bm	121	21	and	and	CC
cord-003130-p2h8p5bm	121	22	trypsin	trypsin	NN
cord-003130-p2h8p5bm	121	23	was	be	VBD
cord-003130-p2h8p5bm	121	24	found	find	VBN
cord-003130-p2h8p5bm	121	25	to	to	TO
cord-003130-p2h8p5bm	121	26	inhibit	inhibit	VB
cord-003130-p2h8p5bm	121	27	LGTV	LGTV	NNP
cord-003130-p2h8p5bm	121	28	in	in	IN
cord-003130-p2h8p5bm	121	29	tick	tick	NN
cord-003130-p2h8p5bm	121	30	cells	cell	NNS
cord-003130-p2h8p5bm	121	31	[	[	-LRB-
cord-003130-p2h8p5bm	121	32	94	94	CD
cord-003130-p2h8p5bm	121	33	]	]	-RRB-
cord-003130-p2h8p5bm	121	34	.	.	.
cord-003130-p2h8p5bm	122	1	Taken	take	VBN
cord-003130-p2h8p5bm	122	2	together	together	RB
cord-003130-p2h8p5bm	122	3	,	,	,
cord-003130-p2h8p5bm	122	4	studies	study	NNS
cord-003130-p2h8p5bm	122	5	so	so	RB
cord-003130-p2h8p5bm	122	6	far	far	RB
cord-003130-p2h8p5bm	122	7	have	have	VBP
cord-003130-p2h8p5bm	122	8	identified	identify	VBN
cord-003130-p2h8p5bm	122	9	activation	activation	NN
cord-003130-p2h8p5bm	122	10	and	and	CC
cord-003130-p2h8p5bm	122	11	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	122	12	actions	action	NNS
cord-003130-p2h8p5bm	122	13	of	of	IN
cord-003130-p2h8p5bm	122	14	the	the	DT
cord-003130-p2h8p5bm	122	15	RNAi	RNAi	NNP
cord-003130-p2h8p5bm	122	16	mediated	mediate	VBD
cord-003130-p2h8p5bm	122	17	response	response	NN
cord-003130-p2h8p5bm	122	18	in	in	IN
cord-003130-p2h8p5bm	122	19	tick	tick	NN
cord-003130-p2h8p5bm	122	20	cells	cell	NNS
cord-003130-p2h8p5bm	122	21	as	as	RB
cord-003130-p2h8p5bm	122	22	well	well	RB
cord-003130-p2h8p5bm	122	23	as	as	IN
cord-003130-p2h8p5bm	122	24	other	other	JJ
cord-003130-p2h8p5bm	122	25	inhibitory	inhibitory	JJ
cord-003130-p2h8p5bm	122	26	proteins	protein	NNS
cord-003130-p2h8p5bm	122	27	such	such	JJ
cord-003130-p2h8p5bm	122	28	as	as	IN
cord-003130-p2h8p5bm	122	29	HSP70	HSP70	NNP
cord-003130-p2h8p5bm	122	30	,	,	,
cord-003130-p2h8p5bm	122	31	HSP90	HSP90	NNP
cord-003130-p2h8p5bm	122	32	,	,	,
cord-003130-p2h8p5bm	122	33	and	and	CC
cord-003130-p2h8p5bm	122	34	trypsin	trypsin	NN
cord-003130-p2h8p5bm	122	35	.	.	.
cord-003130-p2h8p5bm	123	1	The	the	DT
cord-003130-p2h8p5bm	123	2	innate	innate	JJ
cord-003130-p2h8p5bm	123	3	immune	immune	JJ
cord-003130-p2h8p5bm	123	4	response	response	NN
cord-003130-p2h8p5bm	123	5	provides	provide	VBZ
cord-003130-p2h8p5bm	123	6	the	the	DT
cord-003130-p2h8p5bm	123	7	first	first	JJ
cord-003130-p2h8p5bm	123	8	line	line	NN
cord-003130-p2h8p5bm	123	9	of	of	IN
cord-003130-p2h8p5bm	123	10	defense	defense	NN
cord-003130-p2h8p5bm	123	11	against	against	IN
cord-003130-p2h8p5bm	123	12	viral	viral	JJ
cord-003130-p2h8p5bm	123	13	infections	infection	NNS
cord-003130-p2h8p5bm	123	14	.	.	.
cord-003130-p2h8p5bm	124	1	This	this	DT
cord-003130-p2h8p5bm	124	2	defense	defense	NN
cord-003130-p2h8p5bm	124	3	includes	include	VBZ
cord-003130-p2h8p5bm	124	4	physical	physical	JJ
cord-003130-p2h8p5bm	124	5	and	and	CC
cord-003130-p2h8p5bm	124	6	chemical	chemical	JJ
cord-003130-p2h8p5bm	124	7	barriers	barrier	NNS
cord-003130-p2h8p5bm	124	8	such	such	JJ
cord-003130-p2h8p5bm	124	9	as	as	IN
cord-003130-p2h8p5bm	124	10	the	the	DT
cord-003130-p2h8p5bm	124	11	skin	skin	NN
cord-003130-p2h8p5bm	124	12	and	and	CC
cord-003130-p2h8p5bm	124	13	mucous	mucous	JJ
cord-003130-p2h8p5bm	124	14	membranes	membrane	NNS
cord-003130-p2h8p5bm	124	15	and	and	CC
cord-003130-p2h8p5bm	124	16	the	the	DT
cord-003130-p2h8p5bm	124	17	acidity	acidity	NN
cord-003130-p2h8p5bm	124	18	of	of	IN
cord-003130-p2h8p5bm	124	19	the	the	DT
cord-003130-p2h8p5bm	124	20	stomach	stomach	NN
cord-003130-p2h8p5bm	124	21	.	.	.
cord-003130-p2h8p5bm	125	1	They	-PRON-	PRP
cord-003130-p2h8p5bm	125	2	serve	serve	VBP
cord-003130-p2h8p5bm	125	3	as	as	IN
cord-003130-p2h8p5bm	125	4	an	an	DT
cord-003130-p2h8p5bm	125	5	initial	initial	JJ
cord-003130-p2h8p5bm	125	6	barrier	barrier	NN
cord-003130-p2h8p5bm	125	7	that	that	WDT
cord-003130-p2h8p5bm	125	8	protects	protect	VBZ
cord-003130-p2h8p5bm	125	9	the	the	DT
cord-003130-p2h8p5bm	125	10	host	host	NN
cord-003130-p2h8p5bm	125	11	from	from	IN
cord-003130-p2h8p5bm	125	12	infection	infection	NN
cord-003130-p2h8p5bm	125	13	.	.	.
cord-003130-p2h8p5bm	126	1	Once	once	IN
cord-003130-p2h8p5bm	126	2	these	these	DT
cord-003130-p2h8p5bm	126	3	barriers	barrier	NNS
cord-003130-p2h8p5bm	126	4	have	have	VBP
cord-003130-p2h8p5bm	126	5	been	be	VBN
cord-003130-p2h8p5bm	126	6	breached	breach	VBN
cord-003130-p2h8p5bm	126	7	,	,	,
cord-003130-p2h8p5bm	126	8	the	the	DT
cord-003130-p2h8p5bm	126	9	innate	innate	JJ
cord-003130-p2h8p5bm	126	10	immune	immune	JJ
cord-003130-p2h8p5bm	126	11	response	response	NN
cord-003130-p2h8p5bm	126	12	relies	rely	VBZ
cord-003130-p2h8p5bm	126	13	on	on	IN
cord-003130-p2h8p5bm	126	14	a	a	DT
cord-003130-p2h8p5bm	126	15	set	set	NN
cord-003130-p2h8p5bm	126	16	of	of	IN
cord-003130-p2h8p5bm	126	17	germline	germline	NN
cord-003130-p2h8p5bm	126	18	-	-	HYPH
cord-003130-p2h8p5bm	126	19	encoded	encode	VBN
cord-003130-p2h8p5bm	126	20	receptors	receptor	NNS
cord-003130-p2h8p5bm	126	21	,	,	,
cord-003130-p2h8p5bm	126	22	known	know	VBN
cord-003130-p2h8p5bm	126	23	as	as	IN
cord-003130-p2h8p5bm	126	24	pathogen	pathogen	NN
cord-003130-p2h8p5bm	126	25	recognition	recognition	NN
cord-003130-p2h8p5bm	126	26	receptors	receptor	NNS
cord-003130-p2h8p5bm	126	27	(	(	-LRB-
cord-003130-p2h8p5bm	126	28	PRRs	PRRs	NNP
cord-003130-p2h8p5bm	126	29	)	)	-RRB-
cord-003130-p2h8p5bm	126	30	,	,	,
cord-003130-p2h8p5bm	126	31	which	which	WDT
cord-003130-p2h8p5bm	126	32	recognize	recognize	VBP
cord-003130-p2h8p5bm	126	33	pathogen	pathogen	NN
cord-003130-p2h8p5bm	126	34	specific	specific	JJ
cord-003130-p2h8p5bm	126	35	molecular	molecular	JJ
cord-003130-p2h8p5bm	126	36	patterns	pattern	NNS
cord-003130-p2h8p5bm	126	37	that	that	WDT
cord-003130-p2h8p5bm	126	38	are	be	VBP
cord-003130-p2h8p5bm	126	39	sensed	sense	VBN
cord-003130-p2h8p5bm	126	40	as	as	IN
cord-003130-p2h8p5bm	126	41	a	a	DT
cord-003130-p2h8p5bm	126	42	danger	danger	NN
cord-003130-p2h8p5bm	126	43	signal	signal	NN
cord-003130-p2h8p5bm	126	44	by	by	IN
cord-003130-p2h8p5bm	126	45	the	the	DT
cord-003130-p2h8p5bm	126	46	host	host	NN
cord-003130-p2h8p5bm	126	47	cell	cell	NN
cord-003130-p2h8p5bm	126	48	[	[	-LRB-
cord-003130-p2h8p5bm	126	49	95	95	CD
cord-003130-p2h8p5bm	126	50	,	,	,
cord-003130-p2h8p5bm	126	51	96	96	CD
cord-003130-p2h8p5bm	126	52	]	]	-RRB-
cord-003130-p2h8p5bm	126	53	.	.	.
cord-003130-p2h8p5bm	127	1	Engagement	Engagement	NNP
cord-003130-p2h8p5bm	127	2	of	of	IN
cord-003130-p2h8p5bm	127	3	PRRs	PRRs	NNP
cord-003130-p2h8p5bm	127	4	results	result	NNS
cord-003130-p2h8p5bm	127	5	in	in	IN
cord-003130-p2h8p5bm	127	6	the	the	DT
cord-003130-p2h8p5bm	127	7	activation	activation	NN
cord-003130-p2h8p5bm	127	8	of	of	IN
cord-003130-p2h8p5bm	127	9	several	several	JJ
cord-003130-p2h8p5bm	127	10	defense	defense	NN
cord-003130-p2h8p5bm	127	11	mechanisms	mechanism	NNS
cord-003130-p2h8p5bm	127	12	including	include	VBG
cord-003130-p2h8p5bm	127	13	,	,	,
cord-003130-p2h8p5bm	127	14	production	production	NN
cord-003130-p2h8p5bm	127	15	of	of	IN
cord-003130-p2h8p5bm	127	16	interferon	interferon	NN
cord-003130-p2h8p5bm	127	17	(	(	-LRB-
cord-003130-p2h8p5bm	127	18	IFN	IFN	NNP
cord-003130-p2h8p5bm	127	19	)	)	-RRB-
cord-003130-p2h8p5bm	127	20	,	,	,
cord-003130-p2h8p5bm	127	21	induction	induction	NN
cord-003130-p2h8p5bm	127	22	of	of	IN
cord-003130-p2h8p5bm	127	23	phagocytosis	phagocytosis	NN
cord-003130-p2h8p5bm	127	24	,	,	,
cord-003130-p2h8p5bm	127	25	cytokines	cytokine	NNS
cord-003130-p2h8p5bm	127	26	,	,	,
cord-003130-p2h8p5bm	127	27	chemokines	chemokine	NNS
cord-003130-p2h8p5bm	127	28	,	,	,
cord-003130-p2h8p5bm	127	29	antimicrobial	antimicrobial	JJ
cord-003130-p2h8p5bm	127	30	peptides	peptide	NNS
cord-003130-p2h8p5bm	127	31	,	,	,
cord-003130-p2h8p5bm	127	32	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	127	33	proteins	protein	NNS
cord-003130-p2h8p5bm	127	34	,	,	,
cord-003130-p2h8p5bm	127	35	as	as	RB
cord-003130-p2h8p5bm	127	36	well	well	RB
cord-003130-p2h8p5bm	127	37	as	as	IN
cord-003130-p2h8p5bm	127	38	activation	activation	NN
cord-003130-p2h8p5bm	127	39	of	of	IN
cord-003130-p2h8p5bm	127	40	leukocytes	leukocyte	NNS
cord-003130-p2h8p5bm	127	41	and	and	CC
cord-003130-p2h8p5bm	127	42	T	t	NN
cord-003130-p2h8p5bm	127	43	-	-	HYPH
cord-003130-p2h8p5bm	127	44	cells	cell	NNS
cord-003130-p2h8p5bm	127	45	.	.	.
cord-003130-p2h8p5bm	128	1	Furthermore	furthermore	RB
cord-003130-p2h8p5bm	128	2	,	,	,
cord-003130-p2h8p5bm	128	3	the	the	DT
cord-003130-p2h8p5bm	128	4	innate	innate	JJ
cord-003130-p2h8p5bm	128	5	immune	immune	JJ
cord-003130-p2h8p5bm	128	6	response	response	NN
cord-003130-p2h8p5bm	128	7	harbors	harbor	VBZ
cord-003130-p2h8p5bm	128	8	cellular	cellular	JJ
cord-003130-p2h8p5bm	128	9	components	component	NNS
cord-003130-p2h8p5bm	128	10	,	,	,
cord-003130-p2h8p5bm	128	11	such	such	JJ
cord-003130-p2h8p5bm	128	12	as	as	IN
cord-003130-p2h8p5bm	128	13	dendritic	dendritic	JJ
cord-003130-p2h8p5bm	128	14	cells	cell	NNS
cord-003130-p2h8p5bm	128	15	,	,	,
cord-003130-p2h8p5bm	128	16	macrophages	macrophage	NNS
cord-003130-p2h8p5bm	128	17	,	,	,
cord-003130-p2h8p5bm	128	18	and	and	CC
cord-003130-p2h8p5bm	128	19	natural	natural	JJ
cord-003130-p2h8p5bm	128	20	killer	killer	NN
cord-003130-p2h8p5bm	128	21	(	(	-LRB-
cord-003130-p2h8p5bm	128	22	NK	NK	NNP
cord-003130-p2h8p5bm	128	23	)	)	-RRB-
cord-003130-p2h8p5bm	128	24	cells	cell	NNS
cord-003130-p2h8p5bm	128	25	[	[	-LRB-
cord-003130-p2h8p5bm	128	26	97	97	CD
cord-003130-p2h8p5bm	128	27	]	]	-RRB-
cord-003130-p2h8p5bm	128	28	.	.	.
cord-003130-p2h8p5bm	129	1	In	in	IN
cord-003130-p2h8p5bm	129	2	1957	1957	CD
cord-003130-p2h8p5bm	129	3	Isaacs	Isaacs	NNP
cord-003130-p2h8p5bm	129	4	and	and	CC
cord-003130-p2h8p5bm	129	5	Lindenmann	Lindenmann	NNP
cord-003130-p2h8p5bm	129	6	discovered	discover	VBD
cord-003130-p2h8p5bm	129	7	IFN	IFN	NNP
cord-003130-p2h8p5bm	129	8	as	as	IN
cord-003130-p2h8p5bm	129	9	a	a	DT
cord-003130-p2h8p5bm	129	10	secreted	secrete	VBN
cord-003130-p2h8p5bm	129	11	factor	factor	NN
cord-003130-p2h8p5bm	129	12	that	that	WDT
cord-003130-p2h8p5bm	129	13	interfered	interfere	VBD
cord-003130-p2h8p5bm	129	14	with	with	IN
cord-003130-p2h8p5bm	129	15	viral	viral	JJ
cord-003130-p2h8p5bm	129	16	replication	replication	NN
cord-003130-p2h8p5bm	129	17	[	[	-LRB-
cord-003130-p2h8p5bm	129	18	98	98	CD
cord-003130-p2h8p5bm	129	19	]	]	-RRB-
cord-003130-p2h8p5bm	129	20	.	.	.
cord-003130-p2h8p5bm	130	1	In	in	IN
cord-003130-p2h8p5bm	130	2	the	the	DT
cord-003130-p2h8p5bm	130	3	early	early	JJ
cord-003130-p2h8p5bm	130	4	pioneer	pioneer	NN
cord-003130-p2h8p5bm	130	5	work	work	NN
cord-003130-p2h8p5bm	130	6	on	on	IN
cord-003130-p2h8p5bm	130	7	IFN	IFN	NNP
cord-003130-p2h8p5bm	130	8	in	in	IN
cord-003130-p2h8p5bm	130	9	the	the	DT
cord-003130-p2h8p5bm	130	10	fifties	fifty	NNS
cord-003130-p2h8p5bm	130	11	and	and	CC
cord-003130-p2h8p5bm	130	12	sixties	sixty	NNS
cord-003130-p2h8p5bm	130	13	,	,	,
cord-003130-p2h8p5bm	130	14	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	130	15	served	serve	VBD
cord-003130-p2h8p5bm	130	16	as	as	IN
cord-003130-p2h8p5bm	130	17	a	a	DT
cord-003130-p2h8p5bm	130	18	model	model	NN
cord-003130-p2h8p5bm	130	19	system	system	NN
cord-003130-p2h8p5bm	130	20	,	,	,
cord-003130-p2h8p5bm	130	21	and	and	CC
cord-003130-p2h8p5bm	130	22	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	130	23	was	be	VBD
cord-003130-p2h8p5bm	130	24	shown	show	VBN
cord-003130-p2h8p5bm	130	25	to	to	TO
cord-003130-p2h8p5bm	130	26	induce	induce	VB
cord-003130-p2h8p5bm	130	27	IFN	IFN	NNP
cord-003130-p2h8p5bm	130	28	after	after	IN
cord-003130-p2h8p5bm	130	29	infection	infection	NN
cord-003130-p2h8p5bm	130	30	and	and	CC
cord-003130-p2h8p5bm	130	31	was	be	VBD
cord-003130-p2h8p5bm	130	32	also	also	RB
cord-003130-p2h8p5bm	130	33	sensitive	sensitive	JJ
cord-003130-p2h8p5bm	130	34	to	to	IN
cord-003130-p2h8p5bm	130	35	pretreatment	pretreatment	NN
cord-003130-p2h8p5bm	130	36	of	of	IN
cord-003130-p2h8p5bm	130	37	IFNs	ifn	NNS
cord-003130-p2h8p5bm	130	38	[	[	-LRB-
cord-003130-p2h8p5bm	130	39	80	80	CD
cord-003130-p2h8p5bm	130	40	,	,	,
cord-003130-p2h8p5bm	130	41	[	[	-LRB-
cord-003130-p2h8p5bm	130	42	99	99	CD
cord-003130-p2h8p5bm	130	43	]	]	-RRB-
cord-003130-p2h8p5bm	130	44	[	[	-LRB-
cord-003130-p2h8p5bm	130	45	100	100	CD
cord-003130-p2h8p5bm	130	46	]	]	-RRB-
cord-003130-p2h8p5bm	130	47	[	[	-LRB-
cord-003130-p2h8p5bm	130	48	101	101	CD
cord-003130-p2h8p5bm	130	49	]	]	-RRB-
cord-003130-p2h8p5bm	130	50	[	[	-LRB-
cord-003130-p2h8p5bm	130	51	102	102	CD
cord-003130-p2h8p5bm	130	52	]	]	-RRB-
cord-003130-p2h8p5bm	130	53	.	.	.
cord-003130-p2h8p5bm	131	1	Pretreatment	pretreatment	NN
cord-003130-p2h8p5bm	131	2	of	of	IN
cord-003130-p2h8p5bm	131	3	IFN	IFN	NNP
cord-003130-p2h8p5bm	131	4	was	be	VBD
cord-003130-p2h8p5bm	131	5	also	also	RB
cord-003130-p2h8p5bm	131	6	found	find	VBN
cord-003130-p2h8p5bm	131	7	to	to	TO
cord-003130-p2h8p5bm	131	8	inhibit	inhibit	VB
cord-003130-p2h8p5bm	131	9	KFDV	KFDV	NNP
cord-003130-p2h8p5bm	131	10	,	,	,
cord-003130-p2h8p5bm	131	11	OHFV	OHFV	NNP
cord-003130-p2h8p5bm	131	12	,	,	,
cord-003130-p2h8p5bm	131	13	and	and	CC
cord-003130-p2h8p5bm	131	14	POWV	POWV	NNP
cord-003130-p2h8p5bm	131	15	titers	titer	NNS
cord-003130-p2h8p5bm	131	16	in	in	IN
cord-003130-p2h8p5bm	131	17	A549	A549	NNP
cord-003130-p2h8p5bm	131	18	cells	cell	NNS
cord-003130-p2h8p5bm	131	19	(	(	-LRB-
cord-003130-p2h8p5bm	131	20	adenocarcinomic	adenocarcinomic	NNP
cord-003130-p2h8p5bm	131	21	human	human	JJ
cord-003130-p2h8p5bm	131	22	alveolar	alveolar	NN
cord-003130-p2h8p5bm	131	23	basal	basal	NN
cord-003130-p2h8p5bm	131	24	epithelial	epithelial	JJ
cord-003130-p2h8p5bm	131	25	cells	cell	NNS
cord-003130-p2h8p5bm	131	26	)	)	-RRB-
cord-003130-p2h8p5bm	131	27	[	[	-LRB-
cord-003130-p2h8p5bm	131	28	103	103	CD
cord-003130-p2h8p5bm	131	29	]	]	-RRB-
cord-003130-p2h8p5bm	131	30	,	,	,
cord-003130-p2h8p5bm	131	31	thus	thus	RB
cord-003130-p2h8p5bm	131	32	IFN	IFN	NNP
cord-003130-p2h8p5bm	131	33	pretreatment	pretreatment	NN
cord-003130-p2h8p5bm	131	34	induced	induce	VBD
cord-003130-p2h8p5bm	131	35	broad	broad	JJ
cord-003130-p2h8p5bm	131	36	spectrum	spectrum	NN
cord-003130-p2h8p5bm	131	37	inhibition	inhibition	NN
cord-003130-p2h8p5bm	131	38	of	of	IN
cord-003130-p2h8p5bm	131	39	TBFVs	tbfv	NNS
cord-003130-p2h8p5bm	131	40	.	.	.
cord-003130-p2h8p5bm	132	1	IFN	IFN	NNP
cord-003130-p2h8p5bm	132	2	has	have	VBZ
cord-003130-p2h8p5bm	132	3	also	also	RB
cord-003130-p2h8p5bm	132	4	been	be	VBN
cord-003130-p2h8p5bm	132	5	found	find	VBN
cord-003130-p2h8p5bm	132	6	to	to	TO
cord-003130-p2h8p5bm	132	7	be	be	VB
cord-003130-p2h8p5bm	132	8	strongly	strongly	RB
cord-003130-p2h8p5bm	132	9	induced	induce	VBN
cord-003130-p2h8p5bm	132	10	in	in	IN
cord-003130-p2h8p5bm	132	11	the	the	DT
cord-003130-p2h8p5bm	132	12	brains	brain	NNS
cord-003130-p2h8p5bm	132	13	of	of	IN
cord-003130-p2h8p5bm	132	14	POWV	POWV	NNP
cord-003130-p2h8p5bm	132	15	infected	infect	VBN
cord-003130-p2h8p5bm	132	16	Peromyscus	Peromyscus	NNP
cord-003130-p2h8p5bm	132	17	lecuopus	lecuopus	NN
cord-003130-p2h8p5bm	132	18	,	,	,
cord-003130-p2h8p5bm	132	19	which	which	WDT
cord-003130-p2h8p5bm	132	20	are	be	VBP
cord-003130-p2h8p5bm	132	21	known	know	VBN
cord-003130-p2h8p5bm	132	22	as	as	IN
cord-003130-p2h8p5bm	132	23	a	a	DT
cord-003130-p2h8p5bm	132	24	natural	natural	JJ
cord-003130-p2h8p5bm	132	25	host	host	NN
cord-003130-p2h8p5bm	132	26	of	of	IN
cord-003130-p2h8p5bm	132	27	the	the	DT
cord-003130-p2h8p5bm	132	28	virus	virus	NN
cord-003130-p2h8p5bm	132	29	[	[	-LRB-
cord-003130-p2h8p5bm	132	30	104	104	CD
cord-003130-p2h8p5bm	132	31	]	]	-RRB-
cord-003130-p2h8p5bm	132	32	.	.	.
cord-003130-p2h8p5bm	133	1	Similarly	similarly	RB
cord-003130-p2h8p5bm	133	2	,	,	,
cord-003130-p2h8p5bm	133	3	IFN	IFN	NNP
cord-003130-p2h8p5bm	133	4	was	be	VBD
cord-003130-p2h8p5bm	133	5	found	find	VBN
cord-003130-p2h8p5bm	133	6	to	to	TO
cord-003130-p2h8p5bm	133	7	be	be	VB
cord-003130-p2h8p5bm	133	8	induced	induce	VBN
cord-003130-p2h8p5bm	133	9	in	in	IN
cord-003130-p2h8p5bm	133	10	sheep	sheep	NNS
cord-003130-p2h8p5bm	133	11	infected	infect	VBN
cord-003130-p2h8p5bm	133	12	with	with	IN
cord-003130-p2h8p5bm	133	13	LIV	LIV	NNP
cord-003130-p2h8p5bm	133	14	[	[	-LRB-
cord-003130-p2h8p5bm	133	15	105	105	CD
cord-003130-p2h8p5bm	133	16	]	]	-RRB-
cord-003130-p2h8p5bm	133	17	,	,	,
cord-003130-p2h8p5bm	133	18	and	and	CC
cord-003130-p2h8p5bm	133	19	IFN	IFN	NNP
cord-003130-p2h8p5bm	133	20	-	-	HYPH
cord-003130-p2h8p5bm	133	21	stimulated	stimulate	VBN
cord-003130-p2h8p5bm	133	22	genes	gene	NNS
cord-003130-p2h8p5bm	133	23	were	be	VBD
cord-003130-p2h8p5bm	133	24	induced	induce	VBN
cord-003130-p2h8p5bm	133	25	in	in	IN
cord-003130-p2h8p5bm	133	26	brains	brain	NNS
cord-003130-p2h8p5bm	133	27	of	of	IN
cord-003130-p2h8p5bm	133	28	KFDV	KFDV	NNP
cord-003130-p2h8p5bm	133	29	infected	infect	VBN
cord-003130-p2h8p5bm	133	30	mice	mouse	NNS
cord-003130-p2h8p5bm	133	31	,	,	,
cord-003130-p2h8p5bm	133	32	indicating	indicate	VBG
cord-003130-p2h8p5bm	133	33	an	an	DT
cord-003130-p2h8p5bm	133	34	activated	activate	VBN
cord-003130-p2h8p5bm	133	35	IFN	IFN	NNP
cord-003130-p2h8p5bm	133	36	response	response	NN
cord-003130-p2h8p5bm	133	37	[	[	-LRB-
cord-003130-p2h8p5bm	133	38	106	106	CD
cord-003130-p2h8p5bm	133	39	]	]	-RRB-
cord-003130-p2h8p5bm	133	40	.	.	.
cord-003130-p2h8p5bm	134	1	Three	three	CD
cord-003130-p2h8p5bm	134	2	distinct	distinct	JJ
cord-003130-p2h8p5bm	134	3	classes	class	NNS
cord-003130-p2h8p5bm	134	4	of	of	IN
cord-003130-p2h8p5bm	134	5	IFN	IFN	NNP
cord-003130-p2h8p5bm	134	6	,	,	,
cord-003130-p2h8p5bm	134	7	type	type	NN
cord-003130-p2h8p5bm	134	8	I	-PRON-	PRP
cord-003130-p2h8p5bm	134	9	(	(	-LRB-
cord-003130-p2h8p5bm	134	10	IFN	IFN	NNP
cord-003130-p2h8p5bm	134	11	α	α	NNP
cord-003130-p2h8p5bm	134	12	and	and	CC
cord-003130-p2h8p5bm	134	13	β	β	NN
cord-003130-p2h8p5bm	134	14	)	)	-RRB-
cord-003130-p2h8p5bm	134	15	,	,	,
cord-003130-p2h8p5bm	134	16	type	type	NN
cord-003130-p2h8p5bm	134	17	II	II	NNP
cord-003130-p2h8p5bm	134	18	(	(	-LRB-
cord-003130-p2h8p5bm	134	19	IFNγ	IFNγ	NNS
cord-003130-p2h8p5bm	134	20	)	)	-RRB-
cord-003130-p2h8p5bm	134	21	,	,	,
cord-003130-p2h8p5bm	134	22	and	and	CC
cord-003130-p2h8p5bm	134	23	type	type	NN
cord-003130-p2h8p5bm	134	24	III	III	NNP
cord-003130-p2h8p5bm	134	25	IFN	IFN	NNP
cord-003130-p2h8p5bm	134	26	(	(	-LRB-
cord-003130-p2h8p5bm	134	27	IFNλ	IFNλ	NNS
cord-003130-p2h8p5bm	134	28	)	)	-RRB-
cord-003130-p2h8p5bm	134	29	have	have	VBP
cord-003130-p2h8p5bm	134	30	been	be	VBN
cord-003130-p2h8p5bm	134	31	described	describe	VBN
cord-003130-p2h8p5bm	134	32	.	.	.
cord-003130-p2h8p5bm	135	1	The	the	DT
cord-003130-p2h8p5bm	135	2	expression	expression	NN
cord-003130-p2h8p5bm	135	3	of	of	IN
cord-003130-p2h8p5bm	135	4	the	the	DT
cord-003130-p2h8p5bm	135	5	IFNλ	IFNλ	NNS
cord-003130-p2h8p5bm	135	6	-	-	HYPH
cord-003130-p2h8p5bm	135	7	receptors	receptor	NNS
cord-003130-p2h8p5bm	135	8	and	and	CC
cord-003130-p2h8p5bm	135	9	IFNγ	IFNγ	NNS
cord-003130-p2h8p5bm	135	10	are	be	VBP
cord-003130-p2h8p5bm	135	11	restricted	restrict	VBN
cord-003130-p2h8p5bm	135	12	,	,	,
cord-003130-p2h8p5bm	135	13	but	but	CC
cord-003130-p2h8p5bm	135	14	the	the	DT
cord-003130-p2h8p5bm	135	15	type	type	NN
cord-003130-p2h8p5bm	135	16	I	-PRON-	PRP
cord-003130-p2h8p5bm	135	17	IFNs	ifns	VBP
cord-003130-p2h8p5bm	135	18	can	can	MD
cord-003130-p2h8p5bm	135	19	be	be	VB
cord-003130-p2h8p5bm	135	20	expressed	express	VBN
cord-003130-p2h8p5bm	135	21	by	by	IN
cord-003130-p2h8p5bm	135	22	most	most	JJS
cord-003130-p2h8p5bm	135	23	cell	cell	NN
cord-003130-p2h8p5bm	135	24	types	type	NNS
cord-003130-p2h8p5bm	135	25	and	and	CC
cord-003130-p2h8p5bm	135	26	their	-PRON-	PRP$
cord-003130-p2h8p5bm	135	27	receptor	receptor	NN
cord-003130-p2h8p5bm	135	28	,	,	,
cord-003130-p2h8p5bm	135	29	the	the	DT
cord-003130-p2h8p5bm	135	30	interferon	interferon	NN
cord-003130-p2h8p5bm	135	31	-	-	HYPH
cord-003130-p2h8p5bm	135	32	α	α	NNP
cord-003130-p2h8p5bm	135	33	/	/	SYM
cord-003130-p2h8p5bm	135	34	β	β	NN
cord-003130-p2h8p5bm	135	35	receptor	receptor	NN
cord-003130-p2h8p5bm	135	36	(	(	-LRB-
cord-003130-p2h8p5bm	135	37	IFNAR	IFNAR	NNP
cord-003130-p2h8p5bm	135	38	)	)	-RRB-
cord-003130-p2h8p5bm	135	39	is	be	VBZ
cord-003130-p2h8p5bm	135	40	expressed	express	VBN
cord-003130-p2h8p5bm	135	41	on	on	IN
cord-003130-p2h8p5bm	135	42	all	all	DT
cord-003130-p2h8p5bm	135	43	nucleated	nucleated	JJ
cord-003130-p2h8p5bm	135	44	cells	cell	NNS
cord-003130-p2h8p5bm	135	45	[	[	-LRB-
cord-003130-p2h8p5bm	135	46	107	107	CD
cord-003130-p2h8p5bm	135	47	]	]	-RRB-
cord-003130-p2h8p5bm	135	48	.	.	.
cord-003130-p2h8p5bm	136	1	There	there	EX
cord-003130-p2h8p5bm	136	2	are	be	VBP
cord-003130-p2h8p5bm	136	3	17	17	CD
cord-003130-p2h8p5bm	136	4	different	different	JJ
cord-003130-p2h8p5bm	136	5	type	type	NN
cord-003130-p2h8p5bm	137	1	I	-PRON-	PRP
cord-003130-p2h8p5bm	137	2	IFNs	ifns	VBP
cord-003130-p2h8p5bm	137	3	in	in	IN
cord-003130-p2h8p5bm	137	4	humans	human	NNS
cord-003130-p2h8p5bm	137	5	;	;	:
cord-003130-p2h8p5bm	137	6	these	these	DT
cord-003130-p2h8p5bm	137	7	cytokines	cytokine	NNS
cord-003130-p2h8p5bm	137	8	are	be	VBP
cord-003130-p2h8p5bm	137	9	produced	produce	VBN
cord-003130-p2h8p5bm	137	10	by	by	IN
cord-003130-p2h8p5bm	137	11	cells	cell	NNS
cord-003130-p2h8p5bm	137	12	upon	upon	IN
cord-003130-p2h8p5bm	137	13	recognition	recognition	NN
cord-003130-p2h8p5bm	137	14	of	of	IN
cord-003130-p2h8p5bm	137	15	pathogen	pathogen	NN
cord-003130-p2h8p5bm	137	16	-	-	HYPH
cord-003130-p2h8p5bm	137	17	associated	associate	VBN
cord-003130-p2h8p5bm	137	18	molecular	molecular	JJ
cord-003130-p2h8p5bm	137	19	patterns	pattern	NNS
cord-003130-p2h8p5bm	137	20	,	,	,
cord-003130-p2h8p5bm	137	21	which	which	WDT
cord-003130-p2h8p5bm	137	22	are	be	VBP
cord-003130-p2h8p5bm	137	23	foreign	foreign	JJ
cord-003130-p2h8p5bm	137	24	to	to	IN
cord-003130-p2h8p5bm	137	25	the	the	DT
cord-003130-p2h8p5bm	137	26	host	host	NN
cord-003130-p2h8p5bm	137	27	cell	cell	NN
cord-003130-p2h8p5bm	137	28	[	[	-LRB-
cord-003130-p2h8p5bm	137	29	95	95	CD
cord-003130-p2h8p5bm	137	30	,	,	,
cord-003130-p2h8p5bm	137	31	108	108	CD
cord-003130-p2h8p5bm	137	32	]	]	-RRB-
cord-003130-p2h8p5bm	137	33	,	,	,
cord-003130-p2h8p5bm	137	34	and	and	CC
cord-003130-p2h8p5bm	137	35	mediates	mediate	VBZ
cord-003130-p2h8p5bm	137	36	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	137	37	activity	activity	NN
cord-003130-p2h8p5bm	137	38	by	by	IN
cord-003130-p2h8p5bm	137	39	autocrine	autocrine	NN
cord-003130-p2h8p5bm	137	40	and	and	CC
cord-003130-p2h8p5bm	137	41	paracrine	paracrine	NN
cord-003130-p2h8p5bm	137	42	signaling	signaling	NN
cord-003130-p2h8p5bm	137	43	through	through	IN
cord-003130-p2h8p5bm	137	44	IFNAR	IFNAR	NNP
cord-003130-p2h8p5bm	137	45	[	[	-LRB-
cord-003130-p2h8p5bm	137	46	109	109	CD
cord-003130-p2h8p5bm	137	47	,	,	,
cord-003130-p2h8p5bm	137	48	110	110	CD
cord-003130-p2h8p5bm	137	49	]	]	-RRB-
cord-003130-p2h8p5bm	137	50	.	.	.
cord-003130-p2h8p5bm	138	1	Signaling	signal	VBG
cord-003130-p2h8p5bm	138	2	through	through	IN
cord-003130-p2h8p5bm	138	3	IFNAR	IFNAR	NNP
cord-003130-p2h8p5bm	138	4	induces	induce	VBZ
cord-003130-p2h8p5bm	138	5	an	an	DT
cord-003130-p2h8p5bm	138	6	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	138	7	state	state	NN
cord-003130-p2h8p5bm	138	8	by	by	IN
cord-003130-p2h8p5bm	138	9	the	the	DT
cord-003130-p2h8p5bm	138	10	expression	expression	NN
cord-003130-p2h8p5bm	138	11	of	of	IN
cord-003130-p2h8p5bm	138	12	hundreds	hundred	NNS
cord-003130-p2h8p5bm	138	13	of	of	IN
cord-003130-p2h8p5bm	138	14	interferon	interferon	NN
cord-003130-p2h8p5bm	138	15	stimulated	stimulate	VBD
cord-003130-p2h8p5bm	138	16	genes	gene	NNS
cord-003130-p2h8p5bm	138	17	(	(	-LRB-
cord-003130-p2h8p5bm	138	18	ISGs	ISGs	NNP
cord-003130-p2h8p5bm	138	19	)	)	-RRB-
cord-003130-p2h8p5bm	138	20	[	[	-LRB-
cord-003130-p2h8p5bm	138	21	111	111	CD
cord-003130-p2h8p5bm	138	22	,	,	,
cord-003130-p2h8p5bm	138	23	112	112	CD
cord-003130-p2h8p5bm	138	24	]	]	-RRB-
cord-003130-p2h8p5bm	138	25	.	.	.
cord-003130-p2h8p5bm	139	1	The	the	DT
cord-003130-p2h8p5bm	139	2	host	host	NN
cord-003130-p2h8p5bm	139	3	cell	cell	NN
cord-003130-p2h8p5bm	139	4	detects	detect	VBZ
cord-003130-p2h8p5bm	139	5	invading	invade	VBG
cord-003130-p2h8p5bm	139	6	pathogens	pathogen	NNS
cord-003130-p2h8p5bm	139	7	through	through	IN
cord-003130-p2h8p5bm	139	8	PRRs	prr	NNS
cord-003130-p2h8p5bm	139	9	,	,	,
cord-003130-p2h8p5bm	139	10	which	which	WDT
cord-003130-p2h8p5bm	139	11	recognize	recognize	VBP
cord-003130-p2h8p5bm	139	12	foreign	foreign	JJ
cord-003130-p2h8p5bm	139	13	molecular	molecular	JJ
cord-003130-p2h8p5bm	139	14	patterns	pattern	NNS
cord-003130-p2h8p5bm	139	15	that	that	WDT
cord-003130-p2h8p5bm	139	16	are	be	VBP
cord-003130-p2h8p5bm	139	17	generated	generate	VBN
cord-003130-p2h8p5bm	139	18	during	during	IN
cord-003130-p2h8p5bm	139	19	infection	infection	NN
cord-003130-p2h8p5bm	139	20	.	.	.
cord-003130-p2h8p5bm	140	1	The	the	DT
cord-003130-p2h8p5bm	140	2	particular	particular	JJ
cord-003130-p2h8p5bm	140	3	PRR	PRR	NNP
cord-003130-p2h8p5bm	140	4	involved	involve	VBN
cord-003130-p2h8p5bm	140	5	in	in	IN
cord-003130-p2h8p5bm	140	6	the	the	DT
cord-003130-p2h8p5bm	140	7	recognition	recognition	NN
cord-003130-p2h8p5bm	140	8	of	of	IN
cord-003130-p2h8p5bm	140	9	the	the	DT
cord-003130-p2h8p5bm	140	10	pathogen	pathogen	NN
cord-003130-p2h8p5bm	140	11	depends	depend	VBZ
cord-003130-p2h8p5bm	140	12	on	on	IN
cord-003130-p2h8p5bm	140	13	the	the	DT
cord-003130-p2h8p5bm	140	14	infecting	infect	VBG
cord-003130-p2h8p5bm	140	15	virus	virus	NN
cord-003130-p2h8p5bm	140	16	[	[	-LRB-
cord-003130-p2h8p5bm	140	17	108	108	CD
cord-003130-p2h8p5bm	140	18	]	]	-RRB-
cord-003130-p2h8p5bm	140	19	.	.	.
cord-003130-p2h8p5bm	141	1	In	in	IN
cord-003130-p2h8p5bm	141	2	flavivirus	flavivirus	JJ
cord-003130-p2h8p5bm	141	3	infection	infection	NN
cord-003130-p2h8p5bm	141	4	,	,	,
cord-003130-p2h8p5bm	141	5	the	the	DT
cord-003130-p2h8p5bm	141	6	most	most	RBS
cord-003130-p2h8p5bm	141	7	important	important	JJ
cord-003130-p2h8p5bm	141	8	PRRs	prr	NNS
cord-003130-p2h8p5bm	141	9	are	be	VBP
cord-003130-p2h8p5bm	141	10	Toll	toll	NN
cord-003130-p2h8p5bm	141	11	-	-	HYPH
cord-003130-p2h8p5bm	141	12	like	like	JJ
cord-003130-p2h8p5bm	141	13	receptor	receptor	NN
cord-003130-p2h8p5bm	141	14	(	(	-LRB-
cord-003130-p2h8p5bm	141	15	TLR)3	tlr)3	XX
cord-003130-p2h8p5bm	141	16	,	,	,
cord-003130-p2h8p5bm	141	17	TLR7	TLR7	NNP
cord-003130-p2h8p5bm	141	18	,	,	,
cord-003130-p2h8p5bm	141	19	TLR8	TLR8	NNP
cord-003130-p2h8p5bm	141	20	,	,	,
cord-003130-p2h8p5bm	141	21	retinoic	retinoic	JJ
cord-003130-p2h8p5bm	141	22	acid	acid	NN
cord-003130-p2h8p5bm	141	23	-	-	HYPH
cord-003130-p2h8p5bm	141	24	inducible	inducible	JJ
cord-003130-p2h8p5bm	141	25	gene	gene	NN
cord-003130-p2h8p5bm	141	26	I	i	NN
cord-003130-p2h8p5bm	141	27	(	(	-LRB-
cord-003130-p2h8p5bm	141	28	RIG	rig	NN
cord-003130-p2h8p5bm	141	29	-	-	:
cord-003130-p2h8p5bm	141	30	I	I	NNP
cord-003130-p2h8p5bm	141	31	)	)	-RRB-
cord-003130-p2h8p5bm	141	32	,	,	,
cord-003130-p2h8p5bm	141	33	and	and	CC
cord-003130-p2h8p5bm	141	34	melanoma	melanoma	NN
cord-003130-p2h8p5bm	141	35	differentiation	differentiation	NN
cord-003130-p2h8p5bm	141	36	-	-	HYPH
cord-003130-p2h8p5bm	141	37	associated	associate	VBN
cord-003130-p2h8p5bm	141	38	protein-5	protein-5	NNP
cord-003130-p2h8p5bm	141	39	(	(	-LRB-
cord-003130-p2h8p5bm	141	40	MDA-5	MDA-5	NNP
cord-003130-p2h8p5bm	141	41	)	)	-RRB-
cord-003130-p2h8p5bm	141	42	.	.	.
cord-003130-p2h8p5bm	142	1	TLR3	TLR3	NNP
cord-003130-p2h8p5bm	142	2	recognizes	recognize	VBZ
cord-003130-p2h8p5bm	142	3	double	double	JJ
cord-003130-p2h8p5bm	142	4	stranded	strand	VBN
cord-003130-p2h8p5bm	142	5	(	(	-LRB-
cord-003130-p2h8p5bm	142	6	ds	ds	NNP
cord-003130-p2h8p5bm	142	7	)	)	-RRB-
cord-003130-p2h8p5bm	142	8	RNA	RNA	NNP
cord-003130-p2h8p5bm	142	9	,	,	,
cord-003130-p2h8p5bm	142	10	which	which	WDT
cord-003130-p2h8p5bm	142	11	is	be	VBZ
cord-003130-p2h8p5bm	142	12	formed	form	VBN
cord-003130-p2h8p5bm	142	13	as	as	IN
cord-003130-p2h8p5bm	142	14	an	an	DT
cord-003130-p2h8p5bm	142	15	intermediate	intermediate	NN
cord-003130-p2h8p5bm	142	16	during	during	IN
cord-003130-p2h8p5bm	142	17	flavivirus	flavivirus	JJ
cord-003130-p2h8p5bm	142	18	replication	replication	NN
cord-003130-p2h8p5bm	142	19	[	[	-LRB-
cord-003130-p2h8p5bm	142	20	113	113	CD
cord-003130-p2h8p5bm	142	21	,	,	,
cord-003130-p2h8p5bm	142	22	114	114	CD
cord-003130-p2h8p5bm	142	23	]	]	-RRB-
cord-003130-p2h8p5bm	142	24	.	.	.
cord-003130-p2h8p5bm	143	1	TLR7	TLR7	NNP
cord-003130-p2h8p5bm	143	2	and	and	CC
cord-003130-p2h8p5bm	143	3	8	8	CD
cord-003130-p2h8p5bm	143	4	,	,	,
cord-003130-p2h8p5bm	143	5	which	which	WDT
cord-003130-p2h8p5bm	143	6	are	be	VBP
cord-003130-p2h8p5bm	143	7	located	locate	VBN
cord-003130-p2h8p5bm	143	8	in	in	IN
cord-003130-p2h8p5bm	143	9	the	the	DT
cord-003130-p2h8p5bm	143	10	endosomes	endosome	NNS
cord-003130-p2h8p5bm	143	11	,	,	,
cord-003130-p2h8p5bm	143	12	recognize	recognize	VB
cord-003130-p2h8p5bm	143	13	single	single	JJ
cord-003130-p2h8p5bm	143	14	stranded	strand	VBN
cord-003130-p2h8p5bm	143	15	(	(	-LRB-
cord-003130-p2h8p5bm	143	16	ss	ss	NNP
cord-003130-p2h8p5bm	143	17	)	)	-RRB-
cord-003130-p2h8p5bm	143	18	RNAs	RNAs	NNPS
cord-003130-p2h8p5bm	143	19	,	,	,
cord-003130-p2h8p5bm	143	20	such	such	JJ
cord-003130-p2h8p5bm	143	21	as	as	IN
cord-003130-p2h8p5bm	143	22	the	the	DT
cord-003130-p2h8p5bm	143	23	genomic	genomic	JJ
cord-003130-p2h8p5bm	143	24	RNA	RNA	NNP
cord-003130-p2h8p5bm	143	25	of	of	IN
cord-003130-p2h8p5bm	143	26	flaviviruses	flaviviruses	NNP
cord-003130-p2h8p5bm	143	27	[	[	-LRB-
cord-003130-p2h8p5bm	143	28	95	95	CD
cord-003130-p2h8p5bm	143	29	,	,	,
cord-003130-p2h8p5bm	143	30	[	[	-LRB-
cord-003130-p2h8p5bm	143	31	115	115	CD
cord-003130-p2h8p5bm	143	32	]	]	-RRB-
cord-003130-p2h8p5bm	143	33	[	[	-LRB-
cord-003130-p2h8p5bm	143	34	116	116	CD
cord-003130-p2h8p5bm	143	35	]	]	-RRB-
cord-003130-p2h8p5bm	143	36	[	[	-LRB-
cord-003130-p2h8p5bm	143	37	117	117	CD
cord-003130-p2h8p5bm	143	38	]	]	-RRB-
cord-003130-p2h8p5bm	143	39	.	.	.
cord-003130-p2h8p5bm	144	1	RIG	rig	NN
cord-003130-p2h8p5bm	144	2	-	-	:
cord-003130-p2h8p5bm	144	3	I	I	NNP
cord-003130-p2h8p5bm	144	4	and	and	CC
cord-003130-p2h8p5bm	144	5	MDA-5	MDA-5	NNP
cord-003130-p2h8p5bm	144	6	recognize	recognize	VB
cord-003130-p2h8p5bm	144	7	viral	viral	JJ
cord-003130-p2h8p5bm	144	8	RNA	RNA	NNP
cord-003130-p2h8p5bm	144	9	in	in	IN
cord-003130-p2h8p5bm	144	10	the	the	DT
cord-003130-p2h8p5bm	144	11	cytoplasm	cytoplasm	NN
cord-003130-p2h8p5bm	144	12	of	of	IN
cord-003130-p2h8p5bm	144	13	infected	infected	JJ
cord-003130-p2h8p5bm	144	14	cells	cell	NNS
cord-003130-p2h8p5bm	144	15	;	;	:
cord-003130-p2h8p5bm	144	16	RIG	rig	NN
cord-003130-p2h8p5bm	144	17	-	-	:
cord-003130-p2h8p5bm	144	18	I	-PRON-	PRP
cord-003130-p2h8p5bm	144	19	recognizes	recognize	VBZ
cord-003130-p2h8p5bm	144	20	short	short	JJ
cord-003130-p2h8p5bm	144	21	dsRNA	dsRNA	NNS
cord-003130-p2h8p5bm	144	22	and	and	CC
cord-003130-p2h8p5bm	144	23	5	5	CD
cord-003130-p2h8p5bm	144	24	triphosphorylated	triphosphorylate	VBN
cord-003130-p2h8p5bm	144	25	and	and	CC
cord-003130-p2h8p5bm	144	26	5	5	CD
cord-003130-p2h8p5bm	144	27	diphosphorylated	diphosphorylated	NNP
cord-003130-p2h8p5bm	144	28	ssRNA	ssRNA	NNP
cord-003130-p2h8p5bm	144	29	,	,	,
cord-003130-p2h8p5bm	144	30	whereas	whereas	IN
cord-003130-p2h8p5bm	144	31	MDA-5	MDA-5	NNP
cord-003130-p2h8p5bm	144	32	recognizes	recognize	VBZ
cord-003130-p2h8p5bm	144	33	long	long	RB
cord-003130-p2h8p5bm	145	1	dsRNA	dsrna	JJ
cord-003130-p2h8p5bm	146	1	[	[	-LRB-
cord-003130-p2h8p5bm	146	2	118	118	CD
cord-003130-p2h8p5bm	146	3	]	]	-RRB-
cord-003130-p2h8p5bm	146	4	[	[	-LRB-
cord-003130-p2h8p5bm	146	5	119	119	CD
cord-003130-p2h8p5bm	146	6	]	]	-RRB-
cord-003130-p2h8p5bm	146	7	[	[	-LRB-
cord-003130-p2h8p5bm	146	8	120	120	CD
cord-003130-p2h8p5bm	146	9	]	]	-RRB-
cord-003130-p2h8p5bm	146	10	.	.	.
cord-003130-p2h8p5bm	147	1	Upon	upon	IN
cord-003130-p2h8p5bm	147	2	recognition	recognition	NN
cord-003130-p2h8p5bm	147	3	,	,	,
cord-003130-p2h8p5bm	147	4	the	the	DT
cord-003130-p2h8p5bm	147	5	different	different	JJ
cord-003130-p2h8p5bm	147	6	PRR	PRR	NNP
cord-003130-p2h8p5bm	147	7	will	will	MD
cord-003130-p2h8p5bm	147	8	recruit	recruit	VB
cord-003130-p2h8p5bm	147	9	distinct	distinct	JJ
cord-003130-p2h8p5bm	147	10	adaptor	adaptor	NN
cord-003130-p2h8p5bm	147	11	molecules	molecule	NNS
cord-003130-p2h8p5bm	147	12	.	.	.
cord-003130-p2h8p5bm	148	1	TLR3	TLR3	NNP
cord-003130-p2h8p5bm	148	2	recruits	recruit	VBZ
cord-003130-p2h8p5bm	148	3	TIR	tir	NN
cord-003130-p2h8p5bm	148	4	-	-	HYPH
cord-003130-p2h8p5bm	148	5	domain	domain	NN
cord-003130-p2h8p5bm	148	6	-	-	HYPH
cord-003130-p2h8p5bm	148	7	containing	contain	VBG
cord-003130-p2h8p5bm	148	8	adapter	adapter	NN
cord-003130-p2h8p5bm	148	9	-	-	HYPH
cord-003130-p2h8p5bm	148	10	inducing	induce	VBG
cord-003130-p2h8p5bm	148	11	interferon	interferon	NN
cord-003130-p2h8p5bm	148	12	-	-	HYPH
cord-003130-p2h8p5bm	148	13	β	β	NN
cord-003130-p2h8p5bm	148	14	(	(	-LRB-
cord-003130-p2h8p5bm	148	15	TRIF	TRIF	NNP
cord-003130-p2h8p5bm	148	16	)	)	-RRB-
cord-003130-p2h8p5bm	148	17	[	[	-LRB-
cord-003130-p2h8p5bm	148	18	121	121	CD
cord-003130-p2h8p5bm	148	19	]	]	-RRB-
cord-003130-p2h8p5bm	148	20	,	,	.
cord-003130-p2h8p5bm	149	1	TLR7	TLR7	NNP
cord-003130-p2h8p5bm	149	2	and	and	CC
cord-003130-p2h8p5bm	149	3	8	8	CD
cord-003130-p2h8p5bm	149	4	recruit	recruit	NN
cord-003130-p2h8p5bm	149	5	myeloid	myeloid	JJ
cord-003130-p2h8p5bm	149	6	differentiation	differentiation	NN
cord-003130-p2h8p5bm	149	7	primary	primary	JJ
cord-003130-p2h8p5bm	149	8	response	response	NN
cord-003130-p2h8p5bm	149	9	88	88	CD
cord-003130-p2h8p5bm	149	10	(	(	-LRB-
cord-003130-p2h8p5bm	149	11	Myd88	Myd88	NNP
cord-003130-p2h8p5bm	149	12	)	)	-RRB-
cord-003130-p2h8p5bm	149	13	[	[	-LRB-
cord-003130-p2h8p5bm	149	14	122	122	CD
cord-003130-p2h8p5bm	149	15	]	]	-RRB-
cord-003130-p2h8p5bm	149	16	,	,	,
cord-003130-p2h8p5bm	149	17	whereas	whereas	IN
cord-003130-p2h8p5bm	149	18	the	the	DT
cord-003130-p2h8p5bm	149	19	RIG	rig	NN
cord-003130-p2h8p5bm	149	20	-	-	HYPH
cord-003130-p2h8p5bm	149	21	I	i	NN
cord-003130-p2h8p5bm	149	22	-	-	HYPH
cord-003130-p2h8p5bm	149	23	like	like	JJ
cord-003130-p2h8p5bm	149	24	helicases	helicase	NNS
cord-003130-p2h8p5bm	149	25	,	,	,
cord-003130-p2h8p5bm	149	26	RIG	rig	NN
cord-003130-p2h8p5bm	149	27	-	-	:
cord-003130-p2h8p5bm	149	28	I	I	NNP
cord-003130-p2h8p5bm	149	29	and	and	CC
cord-003130-p2h8p5bm	149	30	MDA-5	MDA-5	NNP
cord-003130-p2h8p5bm	149	31	,	,	,
cord-003130-p2h8p5bm	149	32	recruit	recruit	VB
cord-003130-p2h8p5bm	149	33	interferon	interferon	NN
cord-003130-p2h8p5bm	149	34	-	-	HYPH
cord-003130-p2h8p5bm	149	35	beta	beta	NN
cord-003130-p2h8p5bm	149	36	promoter	promoter	NN
cord-003130-p2h8p5bm	149	37	stimulator-1	stimulator-1	NNP
cord-003130-p2h8p5bm	150	1	(	(	-LRB-
cord-003130-p2h8p5bm	150	2	IPS-1	IPS-1	NNP
cord-003130-p2h8p5bm	150	3	)	)	-RRB-
cord-003130-p2h8p5bm	150	4	(	(	-LRB-
cord-003130-p2h8p5bm	150	5	also	also	RB
cord-003130-p2h8p5bm	150	6	known	know	VBN
cord-003130-p2h8p5bm	150	7	as	as	IN
cord-003130-p2h8p5bm	150	8	mitochondrial	mitochondrial	JJ
cord-003130-p2h8p5bm	150	9	antiviral	antiviral	RB
cord-003130-p2h8p5bm	150	10	-	-	HYPH
cord-003130-p2h8p5bm	150	11	signaling	signal	VBG
cord-003130-p2h8p5bm	150	12	protein	protein	NN
cord-003130-p2h8p5bm	150	13	(	(	-LRB-
cord-003130-p2h8p5bm	150	14	MAVS	MAVS	NNP
cord-003130-p2h8p5bm	150	15	)	)	-RRB-
cord-003130-p2h8p5bm	150	16	,	,	,
cord-003130-p2h8p5bm	150	17	virus	virus	NN
cord-003130-p2h8p5bm	150	18	-	-	HYPH
cord-003130-p2h8p5bm	150	19	induced	induce	VBN
cord-003130-p2h8p5bm	150	20	signaling	signal	VBG
cord-003130-p2h8p5bm	150	21	adapter	adapter	NN
cord-003130-p2h8p5bm	150	22	(	(	-LRB-
cord-003130-p2h8p5bm	150	23	VISA	VISA	NNP
cord-003130-p2h8p5bm	150	24	)	)	-RRB-
cord-003130-p2h8p5bm	150	25	and	and	CC
cord-003130-p2h8p5bm	150	26	CARD	card	NN
cord-003130-p2h8p5bm	150	27	adapter	adapter	NN
cord-003130-p2h8p5bm	150	28	-	-	HYPH
cord-003130-p2h8p5bm	150	29	inducing	induce	VBG
cord-003130-p2h8p5bm	150	30	IFN	IFN	NNP
cord-003130-p2h8p5bm	150	31	-	-	HYPH
cord-003130-p2h8p5bm	150	32	beta	beta	NN
cord-003130-p2h8p5bm	150	33	(	(	-LRB-
cord-003130-p2h8p5bm	150	34	Cardif	Cardif	NNP
cord-003130-p2h8p5bm	150	35	)	)	-RRB-
cord-003130-p2h8p5bm	150	36	)	)	-RRB-
cord-003130-p2h8p5bm	151	1	[	[	-LRB-
cord-003130-p2h8p5bm	151	2	123	123	CD
cord-003130-p2h8p5bm	151	3	]	]	-RRB-
cord-003130-p2h8p5bm	151	4	[	[	-LRB-
cord-003130-p2h8p5bm	151	5	124	124	CD
cord-003130-p2h8p5bm	151	6	]	]	-RRB-
cord-003130-p2h8p5bm	152	1	[	[	-LRB-
cord-003130-p2h8p5bm	152	2	125	125	CD
cord-003130-p2h8p5bm	152	3	]	]	-RRB-
cord-003130-p2h8p5bm	152	4	[	[	-LRB-
cord-003130-p2h8p5bm	152	5	126	126	CD
cord-003130-p2h8p5bm	152	6	]	]	-RRB-
cord-003130-p2h8p5bm	152	7	.	.	.
cord-003130-p2h8p5bm	153	1	Ligation	Ligation	NNP
cord-003130-p2h8p5bm	153	2	of	of	IN
cord-003130-p2h8p5bm	153	3	PRRs	prr	NNS
cord-003130-p2h8p5bm	153	4	and	and	CC
cord-003130-p2h8p5bm	153	5	downstream	downstream	JJ
cord-003130-p2h8p5bm	153	6	recruitment	recruitment	NN
cord-003130-p2h8p5bm	153	7	of	of	IN
cord-003130-p2h8p5bm	153	8	the	the	DT
cord-003130-p2h8p5bm	153	9	adapter	adapter	NN
cord-003130-p2h8p5bm	153	10	molecules	molecule	NNS
cord-003130-p2h8p5bm	153	11	result	result	VBP
cord-003130-p2h8p5bm	153	12	in	in	IN
cord-003130-p2h8p5bm	153	13	the	the	DT
cord-003130-p2h8p5bm	153	14	activation	activation	NN
cord-003130-p2h8p5bm	153	15	of	of	IN
cord-003130-p2h8p5bm	153	16	transcription	transcription	NN
cord-003130-p2h8p5bm	153	17	factors	factor	NNS
cord-003130-p2h8p5bm	153	18	NF	nf	NN
cord-003130-p2h8p5bm	153	19	-	-	HYPH
cord-003130-p2h8p5bm	153	20	κB	κB	NNP
cord-003130-p2h8p5bm	153	21	and	and	CC
cord-003130-p2h8p5bm	153	22	interferon	interferon	NN
cord-003130-p2h8p5bm	153	23	regulatory	regulatory	JJ
cord-003130-p2h8p5bm	153	24	factor	factor	NN
cord-003130-p2h8p5bm	153	25	(	(	-LRB-
cord-003130-p2h8p5bm	153	26	IRF	IRF	NNP
cord-003130-p2h8p5bm	153	27	)	)	-RRB-
cord-003130-p2h8p5bm	153	28	3	3	CD
cord-003130-p2h8p5bm	153	29	and	and	CC
cord-003130-p2h8p5bm	153	30	IRF7	IRF7	NNP
cord-003130-p2h8p5bm	153	31	,	,	,
cord-003130-p2h8p5bm	153	32	which	which	WDT
cord-003130-p2h8p5bm	153	33	translocate	translocate	VBP
cord-003130-p2h8p5bm	153	34	to	to	IN
cord-003130-p2h8p5bm	153	35	the	the	DT
cord-003130-p2h8p5bm	153	36	nucleus	nucleus	NN
cord-003130-p2h8p5bm	153	37	and	and	CC
cord-003130-p2h8p5bm	153	38	induces	induce	VBZ
cord-003130-p2h8p5bm	153	39	the	the	DT
cord-003130-p2h8p5bm	153	40	expression	expression	NN
cord-003130-p2h8p5bm	153	41	and	and	CC
cord-003130-p2h8p5bm	153	42	subsequent	subsequent	JJ
cord-003130-p2h8p5bm	153	43	secretion	secretion	NN
cord-003130-p2h8p5bm	153	44	of	of	IN
cord-003130-p2h8p5bm	153	45	type	type	NN
cord-003130-p2h8p5bm	154	1	I	-PRON-	PRP
cord-003130-p2h8p5bm	154	2	IFN	IFN	NNP
cord-003130-p2h8p5bm	154	3	[	[	-LRB-
cord-003130-p2h8p5bm	154	4	127	127	CD
cord-003130-p2h8p5bm	154	5	]	]	-RRB-
cord-003130-p2h8p5bm	154	6	.	.	.
cord-003130-p2h8p5bm	155	1	Although	although	IN
cord-003130-p2h8p5bm	155	2	the	the	DT
cord-003130-p2h8p5bm	155	3	innate	innate	JJ
cord-003130-p2h8p5bm	155	4	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	155	5	response	response	NN
cord-003130-p2h8p5bm	155	6	has	have	VBZ
cord-003130-p2h8p5bm	155	7	been	be	VBN
cord-003130-p2h8p5bm	155	8	well	well	RB
cord-003130-p2h8p5bm	155	9	-	-	HYPH
cord-003130-p2h8p5bm	155	10	studied	study	VBN
cord-003130-p2h8p5bm	155	11	in	in	IN
cord-003130-p2h8p5bm	155	12	mosquito	mosquito	NN
cord-003130-p2h8p5bm	155	13	-	-	HYPH
cord-003130-p2h8p5bm	155	14	borne	bear	VBN
cord-003130-p2h8p5bm	155	15	flavivirus	flavivirus	JJ
cord-003130-p2h8p5bm	155	16	infection	infection	NN
cord-003130-p2h8p5bm	155	17	,	,	,
cord-003130-p2h8p5bm	155	18	the	the	DT
cord-003130-p2h8p5bm	155	19	responses	response	NNS
cord-003130-p2h8p5bm	155	20	to	to	IN
cord-003130-p2h8p5bm	155	21	TBFVs	tbfv	NNS
cord-003130-p2h8p5bm	155	22	are	be	VBP
cord-003130-p2h8p5bm	155	23	less	less	RBR
cord-003130-p2h8p5bm	155	24	investigated	investigate	VBN
cord-003130-p2h8p5bm	155	25	,	,	,
cord-003130-p2h8p5bm	155	26	and	and	CC
cord-003130-p2h8p5bm	155	27	most	most	JJS
cord-003130-p2h8p5bm	155	28	studies	study	NNS
cord-003130-p2h8p5bm	155	29	have	have	VBP
cord-003130-p2h8p5bm	155	30	used	use	VBN
cord-003130-p2h8p5bm	155	31	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	155	32	which	which	WDT
cord-003130-p2h8p5bm	155	33	therefore	therefore	RB
cord-003130-p2h8p5bm	155	34	will	will	MD
cord-003130-p2h8p5bm	155	35	be	be	VB
cord-003130-p2h8p5bm	155	36	the	the	DT
cord-003130-p2h8p5bm	155	37	main	main	JJ
cord-003130-p2h8p5bm	155	38	focus	focus	NN
cord-003130-p2h8p5bm	155	39	of	of	IN
cord-003130-p2h8p5bm	155	40	the	the	DT
cord-003130-p2h8p5bm	155	41	remainder	remainder	NN
cord-003130-p2h8p5bm	155	42	of	of	IN
cord-003130-p2h8p5bm	155	43	this	this	DT
cord-003130-p2h8p5bm	155	44	review	review	NN
cord-003130-p2h8p5bm	155	45	.	.	.
cord-003130-p2h8p5bm	156	1	In	in	IN
cord-003130-p2h8p5bm	156	2	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	156	3	infection	infection	NN
cord-003130-p2h8p5bm	156	4	,	,	,
cord-003130-p2h8p5bm	156	5	IFNβ	IFNβ	NNS
cord-003130-p2h8p5bm	156	6	induction	induction	NN
cord-003130-p2h8p5bm	156	7	has	have	VBZ
cord-003130-p2h8p5bm	156	8	been	be	VBN
cord-003130-p2h8p5bm	156	9	shown	show	VBN
cord-003130-p2h8p5bm	156	10	to	to	TO
cord-003130-p2h8p5bm	156	11	correlate	correlate	VB
cord-003130-p2h8p5bm	156	12	with	with	IN
cord-003130-p2h8p5bm	156	13	amount	amount	NN
cord-003130-p2h8p5bm	156	14	of	of	IN
cord-003130-p2h8p5bm	156	15	intracellular	intracellular	JJ
cord-003130-p2h8p5bm	156	16	viral	viral	JJ
cord-003130-p2h8p5bm	156	17	RNA	RNA	NNP
cord-003130-p2h8p5bm	156	18	,	,	,
cord-003130-p2h8p5bm	156	19	and	and	CC
cord-003130-p2h8p5bm	156	20	the	the	DT
cord-003130-p2h8p5bm	156	21	IPS-1	IPS-1	NNP
cord-003130-p2h8p5bm	156	22	pathway	pathway	NN
cord-003130-p2h8p5bm	156	23	has	have	VBZ
cord-003130-p2h8p5bm	156	24	been	be	VBN
cord-003130-p2h8p5bm	156	25	shown	show	VBN
cord-003130-p2h8p5bm	156	26	to	to	TO
cord-003130-p2h8p5bm	156	27	protect	protect	VB
cord-003130-p2h8p5bm	156	28	mice	mouse	NNS
cord-003130-p2h8p5bm	156	29	from	from	IN
cord-003130-p2h8p5bm	156	30	lethal	lethal	JJ
cord-003130-p2h8p5bm	156	31	LGTV	LGTV	NNP
cord-003130-p2h8p5bm	156	32	infection	infection	NN
cord-003130-p2h8p5bm	156	33	and	and	CC
cord-003130-p2h8p5bm	156	34	prolong	prolong	VB
cord-003130-p2h8p5bm	156	35	survival	survival	NN
cord-003130-p2h8p5bm	156	36	after	after	IN
cord-003130-p2h8p5bm	156	37	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	156	38	infection	infection	NN
cord-003130-p2h8p5bm	156	39	[	[	-LRB-
cord-003130-p2h8p5bm	156	40	80	80	CD
cord-003130-p2h8p5bm	156	41	,	,	,
cord-003130-p2h8p5bm	156	42	128	128	CD
cord-003130-p2h8p5bm	156	43	]	]	-RRB-
cord-003130-p2h8p5bm	156	44	.	.	.
cord-003130-p2h8p5bm	157	1	Absence	absence	NN
cord-003130-p2h8p5bm	157	2	of	of	IN
cord-003130-p2h8p5bm	157	3	IPS-1	IPS-1	NNP
cord-003130-p2h8p5bm	157	4	resulted	result	VBD
cord-003130-p2h8p5bm	157	5	in	in	IN
cord-003130-p2h8p5bm	157	6	a	a	DT
cord-003130-p2h8p5bm	157	7	lower	low	JJR
cord-003130-p2h8p5bm	157	8	systemic	systemic	JJ
cord-003130-p2h8p5bm	157	9	IFNα	IFNα	NNS
cord-003130-p2h8p5bm	157	10	response	response	NN
cord-003130-p2h8p5bm	157	11	,	,	,
cord-003130-p2h8p5bm	157	12	which	which	WDT
cord-003130-p2h8p5bm	157	13	correlated	correlate	VBD
cord-003130-p2h8p5bm	157	14	with	with	IN
cord-003130-p2h8p5bm	157	15	higher	high	JJR
cord-003130-p2h8p5bm	157	16	viral	viral	JJ
cord-003130-p2h8p5bm	157	17	replication	replication	NN
cord-003130-p2h8p5bm	157	18	in	in	IN
cord-003130-p2h8p5bm	157	19	the	the	DT
cord-003130-p2h8p5bm	157	20	peripheral	peripheral	JJ
cord-003130-p2h8p5bm	157	21	tissues	tissue	NNS
cord-003130-p2h8p5bm	157	22	[	[	-LRB-
cord-003130-p2h8p5bm	157	23	128	128	CD
cord-003130-p2h8p5bm	157	24	]	]	-RRB-
cord-003130-p2h8p5bm	157	25	.	.	.
cord-003130-p2h8p5bm	158	1	Furthermore	furthermore	RB
cord-003130-p2h8p5bm	158	2	,	,	,
cord-003130-p2h8p5bm	158	3	IPS-1	IPS-1	NNP
cord-003130-p2h8p5bm	158	4	was	be	VBD
cord-003130-p2h8p5bm	158	5	shown	show	VBN
cord-003130-p2h8p5bm	158	6	to	to	TO
cord-003130-p2h8p5bm	158	7	be	be	VB
cord-003130-p2h8p5bm	158	8	of	of	IN
cord-003130-p2h8p5bm	158	9	particular	particular	JJ
cord-003130-p2h8p5bm	158	10	importance	importance	NN
cord-003130-p2h8p5bm	158	11	for	for	IN
cord-003130-p2h8p5bm	158	12	the	the	DT
cord-003130-p2h8p5bm	158	13	IFN	IFN	NNP
cord-003130-p2h8p5bm	158	14	production	production	NN
cord-003130-p2h8p5bm	158	15	locally	locally	RB
cord-003130-p2h8p5bm	158	16	within	within	IN
cord-003130-p2h8p5bm	158	17	the	the	DT
cord-003130-p2h8p5bm	158	18	brain	brain	NN
cord-003130-p2h8p5bm	158	19	,	,	,
cord-003130-p2h8p5bm	158	20	where	where	WRB
cord-003130-p2h8p5bm	158	21	IPS-1	IPS-1	NNP
cord-003130-p2h8p5bm	158	22	−/−	−/−	NNP
cord-003130-p2h8p5bm	158	23	mice	mouse	NNS
cord-003130-p2h8p5bm	158	24	had	have	VBD
cord-003130-p2h8p5bm	158	25	lower	low	JJR
cord-003130-p2h8p5bm	158	26	induction	induction	NN
cord-003130-p2h8p5bm	158	27	of	of	IN
cord-003130-p2h8p5bm	158	28	IFNβ	IFNβ	NNS
cord-003130-p2h8p5bm	158	29	within	within	IN
cord-003130-p2h8p5bm	158	30	the	the	DT
cord-003130-p2h8p5bm	158	31	olfactory	olfactory	JJ
cord-003130-p2h8p5bm	158	32	bulb	bulb	NN
cord-003130-p2h8p5bm	158	33	despite	despite	IN
cord-003130-p2h8p5bm	158	34	higher	high	JJR
cord-003130-p2h8p5bm	158	35	viral	viral	JJ
cord-003130-p2h8p5bm	158	36	burdens	burden	NNS
cord-003130-p2h8p5bm	158	37	[	[	-LRB-
cord-003130-p2h8p5bm	158	38	128	128	CD
cord-003130-p2h8p5bm	158	39	]	]	-RRB-
cord-003130-p2h8p5bm	158	40	.	.	.
cord-003130-p2h8p5bm	159	1	Furthermore	furthermore	RB
cord-003130-p2h8p5bm	159	2	,	,	,
cord-003130-p2h8p5bm	159	3	IFNβ	IFNβ	NNS
cord-003130-p2h8p5bm	159	4	induction	induction	NN
cord-003130-p2h8p5bm	159	5	was	be	VBD
cord-003130-p2h8p5bm	159	6	shown	show	VBN
cord-003130-p2h8p5bm	159	7	to	to	TO
cord-003130-p2h8p5bm	159	8	be	be	VB
cord-003130-p2h8p5bm	159	9	completely	completely	RB
cord-003130-p2h8p5bm	159	10	dependent	dependent	JJ
cord-003130-p2h8p5bm	159	11	on	on	IN
cord-003130-p2h8p5bm	159	12	IPS-1	IPS-1	NNP
cord-003130-p2h8p5bm	159	13	and	and	CC
cord-003130-p2h8p5bm	159	14	IRF3	IRF3	NNP
cord-003130-p2h8p5bm	159	15	in	in	IN
cord-003130-p2h8p5bm	159	16	mouse	mouse	NN
cord-003130-p2h8p5bm	159	17	embryonic	embryonic	JJ
cord-003130-p2h8p5bm	159	18	fibroblasts	fibroblast	NNS
cord-003130-p2h8p5bm	159	19	and	and	CC
cord-003130-p2h8p5bm	159	20	viral	viral	JJ
cord-003130-p2h8p5bm	159	21	recognition	recognition	NN
cord-003130-p2h8p5bm	159	22	through	through	IN
cord-003130-p2h8p5bm	159	23	the	the	DT
cord-003130-p2h8p5bm	159	24	IPS-1-pathway	ips-1-pathway	NN
cord-003130-p2h8p5bm	159	25	was	be	VBD
cord-003130-p2h8p5bm	159	26	shown	show	VBN
cord-003130-p2h8p5bm	159	27	to	to	TO
cord-003130-p2h8p5bm	159	28	be	be	VB
cord-003130-p2h8p5bm	159	29	dependent	dependent	JJ
cord-003130-p2h8p5bm	159	30	on	on	IN
cord-003130-p2h8p5bm	159	31	RIG	rig	NN
cord-003130-p2h8p5bm	159	32	-	-	:
cord-003130-p2h8p5bm	159	33	I	i	NN
cord-003130-p2h8p5bm	159	34	and	and	CC
cord-003130-p2h8p5bm	159	35	not	not	RB
cord-003130-p2h8p5bm	159	36	MDA-5	MDA-5	VBZ
cord-003130-p2h8p5bm	159	37	in	in	IN
cord-003130-p2h8p5bm	159	38	human	human	JJ
cord-003130-p2h8p5bm	159	39	osteosarcoma	osteosarcoma	NN
cord-003130-p2h8p5bm	159	40	cells	cell	NNS
cord-003130-p2h8p5bm	159	41	(	(	-LRB-
cord-003130-p2h8p5bm	159	42	U2OS	U2OS	NNP
cord-003130-p2h8p5bm	159	43	)	)	-RRB-
cord-003130-p2h8p5bm	159	44	[	[	-LRB-
cord-003130-p2h8p5bm	159	45	80	80	CD
cord-003130-p2h8p5bm	159	46	,	,	,
cord-003130-p2h8p5bm	159	47	83	83	CD
cord-003130-p2h8p5bm	159	48	]	]	-RRB-
cord-003130-p2h8p5bm	159	49	.	.	.
cord-003130-p2h8p5bm	160	1	Interestingly	interestingly	RB
cord-003130-p2h8p5bm	160	2	,	,	,
cord-003130-p2h8p5bm	160	3	RIG	rig	NN
cord-003130-p2h8p5bm	160	4	-	-	:
cord-003130-p2h8p5bm	160	5	I	-PRON-	PRP
cord-003130-p2h8p5bm	160	6	has	have	VBZ
cord-003130-p2h8p5bm	160	7	been	be	VBN
cord-003130-p2h8p5bm	160	8	shown	show	VBN
cord-003130-p2h8p5bm	160	9	to	to	TO
cord-003130-p2h8p5bm	160	10	co	co	VB
cord-003130-p2h8p5bm	160	11	-	-	VB
cord-003130-p2h8p5bm	160	12	localize	localize	VB
cord-003130-p2h8p5bm	160	13	with	with	IN
cord-003130-p2h8p5bm	160	14	stress	stress	NN
cord-003130-p2h8p5bm	160	15	granules	granule	NNS
cord-003130-p2h8p5bm	160	16	(	(	-LRB-
cord-003130-p2h8p5bm	160	17	SG	SG	NNP
cord-003130-p2h8p5bm	160	18	)	)	-RRB-
cord-003130-p2h8p5bm	160	19	during	during	IN
cord-003130-p2h8p5bm	160	20	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	160	21	infection	infection	NN
cord-003130-p2h8p5bm	160	22	[	[	-LRB-
cord-003130-p2h8p5bm	160	23	129	129	CD
cord-003130-p2h8p5bm	160	24	]	]	-RRB-
cord-003130-p2h8p5bm	160	25	.	.	.
cord-003130-p2h8p5bm	161	1	SG	SG	NNP
cord-003130-p2h8p5bm	161	2	contains	contain	VBZ
cord-003130-p2h8p5bm	161	3	ribonucleoprotein	ribonucleoprotein	NN
cord-003130-p2h8p5bm	161	4	aggregates	aggregate	NNS
cord-003130-p2h8p5bm	161	5	with	with	IN
cord-003130-p2h8p5bm	161	6	translationally	translationally	RB
cord-003130-p2h8p5bm	161	7	stalled	stall	VBN
cord-003130-p2h8p5bm	161	8	mRNAs	mRNAs	NNPS
cord-003130-p2h8p5bm	161	9	,	,	,
cord-003130-p2h8p5bm	161	10	40S	40s	CD
cord-003130-p2h8p5bm	161	11	ribosomes	ribosome	NNS
cord-003130-p2h8p5bm	161	12	,	,	,
cord-003130-p2h8p5bm	161	13	and	and	CC
cord-003130-p2h8p5bm	161	14	several	several	JJ
cord-003130-p2h8p5bm	161	15	RNA	rna	NN
cord-003130-p2h8p5bm	161	16	-	-	HYPH
cord-003130-p2h8p5bm	161	17	binding	bind	VBG
cord-003130-p2h8p5bm	161	18	proteins	protein	NNS
cord-003130-p2h8p5bm	161	19	.	.	.
cord-003130-p2h8p5bm	162	1	SG	SG	NNP
cord-003130-p2h8p5bm	162	2	function	function	NN
cord-003130-p2h8p5bm	162	3	to	to	TO
cord-003130-p2h8p5bm	162	4	prevent	prevent	VB
cord-003130-p2h8p5bm	162	5	the	the	DT
cord-003130-p2h8p5bm	162	6	generation	generation	NN
cord-003130-p2h8p5bm	162	7	of	of	IN
cord-003130-p2h8p5bm	162	8	defective	defective	JJ
cord-003130-p2h8p5bm	162	9	proteins	protein	NNS
cord-003130-p2h8p5bm	162	10	[	[	-LRB-
cord-003130-p2h8p5bm	162	11	130	130	CD
cord-003130-p2h8p5bm	162	12	]	]	-RRB-
cord-003130-p2h8p5bm	162	13	.	.	.
cord-003130-p2h8p5bm	163	1	SG	SG	NNP
cord-003130-p2h8p5bm	163	2	are	be	VBP
cord-003130-p2h8p5bm	163	3	induced	induce	VBN
cord-003130-p2h8p5bm	163	4	during	during	IN
cord-003130-p2h8p5bm	163	5	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	163	6	infection	infection	NN
cord-003130-p2h8p5bm	163	7	and	and	CC
cord-003130-p2h8p5bm	163	8	SG	SG	NNP
cord-003130-p2h8p5bm	163	9	components	component	NNS
cord-003130-p2h8p5bm	164	1	TIA-1	TIA-1	NNP
cord-003130-p2h8p5bm	164	2	/	/	SYM
cord-003130-p2h8p5bm	164	3	TIAR	TIAR	NNP
cord-003130-p2h8p5bm	164	4	was	be	VBD
cord-003130-p2h8p5bm	164	5	found	find	VBN
cord-003130-p2h8p5bm	164	6	to	to	TO
cord-003130-p2h8p5bm	164	7	bind	bind	VB
cord-003130-p2h8p5bm	164	8	viral	viral	JJ
cord-003130-p2h8p5bm	164	9	RNA	RNA	NNP
cord-003130-p2h8p5bm	164	10	and	and	CC
cord-003130-p2h8p5bm	164	11	inhibit	inhibit	VB
cord-003130-p2h8p5bm	164	12	viral	viral	JJ
cord-003130-p2h8p5bm	164	13	translation	translation	NN
cord-003130-p2h8p5bm	164	14	[	[	-LRB-
cord-003130-p2h8p5bm	164	15	131	131	CD
cord-003130-p2h8p5bm	164	16	]	]	-RRB-
cord-003130-p2h8p5bm	164	17	.	.	.
cord-003130-p2h8p5bm	165	1	Little	little	JJ
cord-003130-p2h8p5bm	165	2	is	be	VBZ
cord-003130-p2h8p5bm	165	3	known	know	VBN
cord-003130-p2h8p5bm	165	4	about	about	IN
cord-003130-p2h8p5bm	165	5	the	the	DT
cord-003130-p2h8p5bm	165	6	role	role	NN
cord-003130-p2h8p5bm	165	7	of	of	IN
cord-003130-p2h8p5bm	165	8	the	the	DT
cord-003130-p2h8p5bm	165	9	TLR7/8-Myd88	TLR7/8-Myd88	NNP
cord-003130-p2h8p5bm	165	10	pathway	pathway	NN
cord-003130-p2h8p5bm	165	11	in	in	IN
cord-003130-p2h8p5bm	165	12	tick	tick	NN
cord-003130-p2h8p5bm	165	13	-	-	HYPH
cord-003130-p2h8p5bm	165	14	borne	bear	VBN
cord-003130-p2h8p5bm	165	15	flavivirus	flavivirus	JJ
cord-003130-p2h8p5bm	165	16	infection	infection	NN
cord-003130-p2h8p5bm	165	17	;	;	:
cord-003130-p2h8p5bm	165	18	however	however	RB
cord-003130-p2h8p5bm	165	19	,	,	,
cord-003130-p2h8p5bm	165	20	TLR7	TLR7	NNP
cord-003130-p2h8p5bm	165	21	was	be	VBD
cord-003130-p2h8p5bm	165	22	shown	show	VBN
cord-003130-p2h8p5bm	165	23	to	to	TO
cord-003130-p2h8p5bm	165	24	suppress	suppress	VB
cord-003130-p2h8p5bm	165	25	LGTV	LGTV	NNP
cord-003130-p2h8p5bm	165	26	replication	replication	NN
cord-003130-p2h8p5bm	165	27	within	within	IN
cord-003130-p2h8p5bm	165	28	neurons	neuron	NNS
cord-003130-p2h8p5bm	165	29	of	of	IN
cord-003130-p2h8p5bm	165	30	the	the	DT
cord-003130-p2h8p5bm	165	31	brain	brain	NN
cord-003130-p2h8p5bm	165	32	although	although	IN
cord-003130-p2h8p5bm	165	33	it	-PRON-	PRP
cord-003130-p2h8p5bm	165	34	did	do	VBD
cord-003130-p2h8p5bm	165	35	not	not	RB
cord-003130-p2h8p5bm	165	36	affect	affect	VB
cord-003130-p2h8p5bm	165	37	pathogenesis	pathogenesis	NN
cord-003130-p2h8p5bm	165	38	[	[	-LRB-
cord-003130-p2h8p5bm	165	39	132	132	CD
cord-003130-p2h8p5bm	165	40	]	]	-RRB-
cord-003130-p2h8p5bm	165	41	.	.	.
cord-003130-p2h8p5bm	166	1	What	what	WP
cord-003130-p2h8p5bm	166	2	we	-PRON-	PRP
cord-003130-p2h8p5bm	166	3	are	be	VBP
cord-003130-p2h8p5bm	166	4	aware	aware	JJ
cord-003130-p2h8p5bm	166	5	of	of	IN
cord-003130-p2h8p5bm	166	6	;	;	:
cord-003130-p2h8p5bm	166	7	no	no	DT
cord-003130-p2h8p5bm	166	8	animal	animal	NN
cord-003130-p2h8p5bm	166	9	experiments	experiment	NNS
cord-003130-p2h8p5bm	166	10	have	have	VBP
cord-003130-p2h8p5bm	166	11	shown	show	VBN
cord-003130-p2h8p5bm	166	12	any	any	DT
cord-003130-p2h8p5bm	166	13	significance	significance	NN
cord-003130-p2h8p5bm	166	14	of	of	IN
cord-003130-p2h8p5bm	166	15	the	the	DT
cord-003130-p2h8p5bm	166	16	TLR3-TRIF	tlr3-trif	NN
cord-003130-p2h8p5bm	166	17	pathway	pathway	NN
cord-003130-p2h8p5bm	166	18	in	in	IN
cord-003130-p2h8p5bm	166	19	tick	tick	NN
cord-003130-p2h8p5bm	166	20	-	-	HYPH
cord-003130-p2h8p5bm	166	21	borne	bear	VBN
cord-003130-p2h8p5bm	166	22	flavivirus	flavivirus	JJ
cord-003130-p2h8p5bm	166	23	infection	infection	NN
cord-003130-p2h8p5bm	166	24	.	.	.
cord-003130-p2h8p5bm	167	1	However	however	RB
cord-003130-p2h8p5bm	167	2	,	,	,
cord-003130-p2h8p5bm	167	3	several	several	JJ
cord-003130-p2h8p5bm	167	4	studies	study	NNS
cord-003130-p2h8p5bm	167	5	have	have	VBP
cord-003130-p2h8p5bm	167	6	looked	look	VBN
cord-003130-p2h8p5bm	167	7	at	at	IN
cord-003130-p2h8p5bm	167	8	the	the	DT
cord-003130-p2h8p5bm	167	9	prevalence	prevalence	NN
cord-003130-p2h8p5bm	167	10	of	of	IN
cord-003130-p2h8p5bm	167	11	polymorphisms	polymorphism	NNS
cord-003130-p2h8p5bm	167	12	in	in	IN
cord-003130-p2h8p5bm	167	13	the	the	DT
cord-003130-p2h8p5bm	167	14	TLR3	TLR3	NNP
cord-003130-p2h8p5bm	167	15	gene	gene	NN
cord-003130-p2h8p5bm	167	16	in	in	IN
cord-003130-p2h8p5bm	167	17	TBE	TBE	NNP
cord-003130-p2h8p5bm	167	18	patients	patient	NNS
cord-003130-p2h8p5bm	167	19	[	[	-LRB-
cord-003130-p2h8p5bm	167	20	133	133	CD
cord-003130-p2h8p5bm	167	21	]	]	-RRB-
cord-003130-p2h8p5bm	167	22	[	[	-LRB-
cord-003130-p2h8p5bm	167	23	134	134	CD
cord-003130-p2h8p5bm	167	24	]	]	-RRB-
cord-003130-p2h8p5bm	167	25	[	[	-LRB-
cord-003130-p2h8p5bm	167	26	135	135	CD
cord-003130-p2h8p5bm	167	27	]	]	-RRB-
cord-003130-p2h8p5bm	167	28	[	[	-LRB-
cord-003130-p2h8p5bm	167	29	136	136	CD
cord-003130-p2h8p5bm	167	30	]	]	-RRB-
cord-003130-p2h8p5bm	167	31	.	.	.
cord-003130-p2h8p5bm	168	1	In	in	IN
cord-003130-p2h8p5bm	168	2	particular	particular	JJ
cord-003130-p2h8p5bm	168	3	,	,	,
cord-003130-p2h8p5bm	168	4	one	one	CD
cord-003130-p2h8p5bm	168	5	polymorphism	polymorphism	NN
cord-003130-p2h8p5bm	168	6	has	have	VBZ
cord-003130-p2h8p5bm	168	7	been	be	VBN
cord-003130-p2h8p5bm	168	8	investigated	investigate	VBN
cord-003130-p2h8p5bm	168	9	the	the	DT
cord-003130-p2h8p5bm	168	10	T	T	NNP
cord-003130-p2h8p5bm	168	11	allele	allele	NN
cord-003130-p2h8p5bm	168	12	in	in	IN
cord-003130-p2h8p5bm	168	13	rs3775291	rs3775291	NNP
cord-003130-p2h8p5bm	168	14	.	.	.
cord-003130-p2h8p5bm	169	1	This	this	DT
cord-003130-p2h8p5bm	169	2	polymorphism	polymorphism	NN
cord-003130-p2h8p5bm	169	3	has	have	VBZ
cord-003130-p2h8p5bm	169	4	been	be	VBN
cord-003130-p2h8p5bm	169	5	shown	show	VBN
cord-003130-p2h8p5bm	169	6	to	to	TO
cord-003130-p2h8p5bm	169	7	reduce	reduce	VB
cord-003130-p2h8p5bm	169	8	TLR3	TLR3	NNP
cord-003130-p2h8p5bm	169	9	signaling	signal	VBG
cord-003130-p2h8p5bm	169	10	by	by	IN
cord-003130-p2h8p5bm	169	11	about	about	RB
cord-003130-p2h8p5bm	169	12	30	30	CD
cord-003130-p2h8p5bm	169	13	%	%	NN
cord-003130-p2h8p5bm	169	14	[	[	-LRB-
cord-003130-p2h8p5bm	169	15	137	137	CD
cord-003130-p2h8p5bm	169	16	]	]	-RRB-
cord-003130-p2h8p5bm	169	17	.	.	.
cord-003130-p2h8p5bm	170	1	Although	although	IN
cord-003130-p2h8p5bm	170	2	the	the	DT
cord-003130-p2h8p5bm	170	3	data	datum	NNS
cord-003130-p2h8p5bm	170	4	regarding	regard	VBG
cord-003130-p2h8p5bm	170	5	TLR3	TLR3	NNP
cord-003130-p2h8p5bm	170	6	is	be	VBZ
cord-003130-p2h8p5bm	170	7	somewhat	somewhat	RB
cord-003130-p2h8p5bm	170	8	conflicting	conflicting	JJ
cord-003130-p2h8p5bm	170	9	,	,	,
cord-003130-p2h8p5bm	170	10	Grygorczuk	Grygorczuk	NNP
cord-003130-p2h8p5bm	170	11	et	et	FW
cord-003130-p2h8p5bm	170	12	al	al	NNP
cord-003130-p2h8p5bm	170	13	.	.	.
cord-003130-p2h8p5bm	171	1	hypothesized	hypothesize	VBD
cord-003130-p2h8p5bm	171	2	that	that	IN
cord-003130-p2h8p5bm	171	3	a	a	DT
cord-003130-p2h8p5bm	171	4	functional	functional	JJ
cord-003130-p2h8p5bm	171	5	TLR3	TLR3	NNP
cord-003130-p2h8p5bm	171	6	facilitates	facilitate	VBZ
cord-003130-p2h8p5bm	171	7	the	the	DT
cord-003130-p2h8p5bm	171	8	onset	onset	NN
cord-003130-p2h8p5bm	171	9	of	of	IN
cord-003130-p2h8p5bm	171	10	neurological	neurological	JJ
cord-003130-p2h8p5bm	171	11	disease	disease	NN
cord-003130-p2h8p5bm	171	12	[	[	-LRB-
cord-003130-p2h8p5bm	171	13	135	135	CD
cord-003130-p2h8p5bm	171	14	]	]	-RRB-
cord-003130-p2h8p5bm	171	15	by	by	IN
cord-003130-p2h8p5bm	171	16	supporting	support	VBG
cord-003130-p2h8p5bm	171	17	the	the	DT
cord-003130-p2h8p5bm	171	18	penetration	penetration	NN
cord-003130-p2h8p5bm	171	19	through	through	IN
cord-003130-p2h8p5bm	171	20	the	the	DT
cord-003130-p2h8p5bm	171	21	blood	blood	NN
cord-003130-p2h8p5bm	171	22	brain	brain	NN
cord-003130-p2h8p5bm	171	23	barrier	barrier	NN
cord-003130-p2h8p5bm	171	24	,	,	,
cord-003130-p2h8p5bm	171	25	but	but	CC
cord-003130-p2h8p5bm	171	26	has	have	VBZ
cord-003130-p2h8p5bm	171	27	a	a	DT
cord-003130-p2h8p5bm	171	28	protective	protective	JJ
cord-003130-p2h8p5bm	171	29	effect	effect	NN
cord-003130-p2h8p5bm	171	30	during	during	IN
cord-003130-p2h8p5bm	171	31	the	the	DT
cord-003130-p2h8p5bm	171	32	established	establish	VBN
cord-003130-p2h8p5bm	171	33	CNS	CNS	NNP
cord-003130-p2h8p5bm	171	34	infection	infection	NN
cord-003130-p2h8p5bm	171	35	[	[	-LRB-
cord-003130-p2h8p5bm	171	36	134	134	CD
cord-003130-p2h8p5bm	171	37	]	]	-RRB-
cord-003130-p2h8p5bm	171	38	.	.	.
cord-003130-p2h8p5bm	172	1	The	the	DT
cord-003130-p2h8p5bm	172	2	differences	difference	NNS
cord-003130-p2h8p5bm	172	3	between	between	IN
cord-003130-p2h8p5bm	172	4	studies	study	NNS
cord-003130-p2h8p5bm	172	5	might	may	MD
cord-003130-p2h8p5bm	172	6	also	also	RB
cord-003130-p2h8p5bm	172	7	be	be	VB
cord-003130-p2h8p5bm	172	8	connected	connect	VBN
cord-003130-p2h8p5bm	172	9	to	to	IN
cord-003130-p2h8p5bm	172	10	the	the	DT
cord-003130-p2h8p5bm	172	11	different	different	JJ
cord-003130-p2h8p5bm	172	12	subtypes	subtype	NNS
cord-003130-p2h8p5bm	172	13	of	of	IN
cord-003130-p2h8p5bm	172	14	the	the	DT
cord-003130-p2h8p5bm	172	15	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	172	16	strain	strain	NN
cord-003130-p2h8p5bm	172	17	and	and	CC
cord-003130-p2h8p5bm	172	18	the	the	DT
cord-003130-p2h8p5bm	172	19	genetic	genetic	JJ
cord-003130-p2h8p5bm	172	20	background	background	NN
cord-003130-p2h8p5bm	172	21	of	of	IN
cord-003130-p2h8p5bm	172	22	the	the	DT
cord-003130-p2h8p5bm	172	23	studied	study	VBN
cord-003130-p2h8p5bm	172	24	populations	population	NNS
cord-003130-p2h8p5bm	172	25	[	[	-LRB-
cord-003130-p2h8p5bm	172	26	134	134	CD
cord-003130-p2h8p5bm	172	27	]	]	-RRB-
cord-003130-p2h8p5bm	172	28	.	.	.
cord-003130-p2h8p5bm	173	1	Taken	take	VBN
cord-003130-p2h8p5bm	173	2	together	together	RB
cord-003130-p2h8p5bm	173	3	,	,	,
cord-003130-p2h8p5bm	173	4	studies	study	NNS
cord-003130-p2h8p5bm	173	5	so	so	RB
cord-003130-p2h8p5bm	173	6	far	far	RB
cord-003130-p2h8p5bm	173	7	have	have	VBP
cord-003130-p2h8p5bm	173	8	demonstrated	demonstrate	VBN
cord-003130-p2h8p5bm	173	9	the	the	DT
cord-003130-p2h8p5bm	173	10	importance	importance	NN
cord-003130-p2h8p5bm	173	11	of	of	IN
cord-003130-p2h8p5bm	173	12	the	the	DT
cord-003130-p2h8p5bm	173	13	RIG	rig	NN
cord-003130-p2h8p5bm	173	14	-	-	HYPH
cord-003130-p2h8p5bm	173	15	I	i	NN
cord-003130-p2h8p5bm	173	16	-	-	HYPH
cord-003130-p2h8p5bm	173	17	like	like	IN
cord-003130-p2h8p5bm	173	18	-	-	HYPH
cord-003130-p2h8p5bm	173	19	IPS-1	IPS-1	NNP
cord-003130-p2h8p5bm	173	20	pathway	pathway	NN
cord-003130-p2h8p5bm	173	21	in	in	IN
cord-003130-p2h8p5bm	173	22	tick	tick	NN
cord-003130-p2h8p5bm	173	23	-	-	HYPH
cord-003130-p2h8p5bm	173	24	borne	bear	VBN
cord-003130-p2h8p5bm	173	25	flavivirus	flavivirus	JJ
cord-003130-p2h8p5bm	173	26	infection	infection	NN
cord-003130-p2h8p5bm	173	27	,	,	,
cord-003130-p2h8p5bm	173	28	whereas	whereas	IN
cord-003130-p2h8p5bm	173	29	the	the	DT
cord-003130-p2h8p5bm	173	30	role	role	NN
cord-003130-p2h8p5bm	173	31	of	of	IN
cord-003130-p2h8p5bm	173	32	the	the	DT
cord-003130-p2h8p5bm	173	33	TLR	TLR	NNP
cord-003130-p2h8p5bm	173	34	pathways	pathway	NNS
cord-003130-p2h8p5bm	173	35	remains	remain	VBZ
cord-003130-p2h8p5bm	173	36	unclear	unclear	JJ
cord-003130-p2h8p5bm	173	37	.	.	.
cord-003130-p2h8p5bm	174	1	After	after	IN
cord-003130-p2h8p5bm	174	2	secretion	secretion	NN
cord-003130-p2h8p5bm	174	3	,	,	,
cord-003130-p2h8p5bm	174	4	type	type	NN
cord-003130-p2h8p5bm	174	5	I	-PRON-	PRP
cord-003130-p2h8p5bm	174	6	IFN	IFN	NNP
cord-003130-p2h8p5bm	174	7	signals	signal	VBZ
cord-003130-p2h8p5bm	174	8	in	in	IN
cord-003130-p2h8p5bm	174	9	an	an	DT
cord-003130-p2h8p5bm	174	10	autocrine	autocrine	JJ
cord-003130-p2h8p5bm	174	11	and	and	CC
cord-003130-p2h8p5bm	174	12	paracrine	paracrine	JJ
cord-003130-p2h8p5bm	174	13	manner	manner	NN
cord-003130-p2h8p5bm	174	14	by	by	IN
cord-003130-p2h8p5bm	174	15	binding	bind	VBG
cord-003130-p2h8p5bm	174	16	to	to	IN
cord-003130-p2h8p5bm	174	17	the	the	DT
cord-003130-p2h8p5bm	174	18	heterodimeric	heterodimeric	NNP
cord-003130-p2h8p5bm	174	19	IFNAR	IFNAR	NNP
cord-003130-p2h8p5bm	174	20	,	,	,
cord-003130-p2h8p5bm	174	21	which	which	WDT
cord-003130-p2h8p5bm	174	22	consists	consist	VBZ
cord-003130-p2h8p5bm	174	23	of	of	IN
cord-003130-p2h8p5bm	174	24	two	two	CD
cord-003130-p2h8p5bm	174	25	subunits	subunit	NNS
cord-003130-p2h8p5bm	174	26	,	,	,
cord-003130-p2h8p5bm	174	27	IFNAR1	ifnar1	NN
cord-003130-p2h8p5bm	174	28	and	and	CC
cord-003130-p2h8p5bm	175	1	IFNAR2	IFNAR2	NNP
cord-003130-p2h8p5bm	175	2	[	[	-LRB-
cord-003130-p2h8p5bm	175	3	138	138	CD
cord-003130-p2h8p5bm	175	4	]	]	-RRB-
cord-003130-p2h8p5bm	175	5	.	.	.
cord-003130-p2h8p5bm	176	1	These	these	DT
cord-003130-p2h8p5bm	176	2	subunits	subunit	NNS
cord-003130-p2h8p5bm	176	3	are	be	VBP
cord-003130-p2h8p5bm	176	4	associated	associate	VBN
cord-003130-p2h8p5bm	176	5	with	with	IN
cord-003130-p2h8p5bm	176	6	Janus	Janus	NNP
cord-003130-p2h8p5bm	176	7	activated	activate	VBN
cord-003130-p2h8p5bm	176	8	kinases	kinase	NNS
cord-003130-p2h8p5bm	176	9	(	(	-LRB-
cord-003130-p2h8p5bm	176	10	JAK	JAK	NNP
cord-003130-p2h8p5bm	176	11	)	)	-RRB-
cord-003130-p2h8p5bm	176	12	localized	localize	VBN
cord-003130-p2h8p5bm	176	13	in	in	IN
cord-003130-p2h8p5bm	176	14	the	the	DT
cord-003130-p2h8p5bm	176	15	cytoplasm	cytoplasm	NN
cord-003130-p2h8p5bm	176	16	;	;	:
cord-003130-p2h8p5bm	176	17	IFNAR1	IFNAR1	NNP
cord-003130-p2h8p5bm	176	18	interacts	interact	VBZ
cord-003130-p2h8p5bm	176	19	with	with	IN
cord-003130-p2h8p5bm	176	20	tyrosine	tyrosine	NN
cord-003130-p2h8p5bm	176	21	kinase-2	kinase-2	NNP
cord-003130-p2h8p5bm	176	22	(	(	-LRB-
cord-003130-p2h8p5bm	176	23	Tyk2	Tyk2	NNP
cord-003130-p2h8p5bm	176	24	)	)	-RRB-
cord-003130-p2h8p5bm	176	25	,	,	,
cord-003130-p2h8p5bm	176	26	whereas	whereas	IN
cord-003130-p2h8p5bm	176	27	IFNAR2	IFNAR2	NNP
cord-003130-p2h8p5bm	176	28	interacts	interact	VBZ
cord-003130-p2h8p5bm	176	29	with	with	IN
cord-003130-p2h8p5bm	176	30	JAK1	JAK1	NNP
cord-003130-p2h8p5bm	176	31	.	.	.
cord-003130-p2h8p5bm	177	1	Ligation	ligation	NN
cord-003130-p2h8p5bm	177	2	of	of	IN
cord-003130-p2h8p5bm	177	3	IFNAR	IFNAR	NNP
cord-003130-p2h8p5bm	177	4	results	result	VBZ
cord-003130-p2h8p5bm	177	5	in	in	IN
cord-003130-p2h8p5bm	177	6	activation	activation	NN
cord-003130-p2h8p5bm	177	7	of	of	IN
cord-003130-p2h8p5bm	177	8	Tyk2	Tyk2	NNP
cord-003130-p2h8p5bm	177	9	and	and	CC
cord-003130-p2h8p5bm	177	10	JAK1	JAK1	NNP
cord-003130-p2h8p5bm	177	11	,	,	,
cord-003130-p2h8p5bm	177	12	which	which	WDT
cord-003130-p2h8p5bm	177	13	subsequently	subsequently	RB
cord-003130-p2h8p5bm	177	14	phosphorylate	phosphorylate	VBP
cord-003130-p2h8p5bm	177	15	signal	signal	NN
cord-003130-p2h8p5bm	177	16	transducers	transducer	NNS
cord-003130-p2h8p5bm	177	17	and	and	CC
cord-003130-p2h8p5bm	177	18	activators	activator	NNS
cord-003130-p2h8p5bm	177	19	of	of	IN
cord-003130-p2h8p5bm	177	20	transcription	transcription	NN
cord-003130-p2h8p5bm	177	21	(	(	-LRB-
cord-003130-p2h8p5bm	177	22	STAT)-1	STAT)-1	NNP
cord-003130-p2h8p5bm	177	23	and	and	CC
cord-003130-p2h8p5bm	177	24	STAT-2	STAT-2	NNP
cord-003130-p2h8p5bm	177	25	.	.	.
cord-003130-p2h8p5bm	178	1	Phosphorylated	Phosphorylated	NNP
cord-003130-p2h8p5bm	178	2	STAT-1	STAT-1	NNPS
cord-003130-p2h8p5bm	178	3	and	and	CC
cord-003130-p2h8p5bm	178	4	STAT-2	STAT-2	NNP
cord-003130-p2h8p5bm	178	5	then	then	RB
cord-003130-p2h8p5bm	178	6	form	form	VB
cord-003130-p2h8p5bm	178	7	a	a	DT
cord-003130-p2h8p5bm	178	8	heterodimer	heterodimer	NN
cord-003130-p2h8p5bm	178	9	,	,	,
cord-003130-p2h8p5bm	178	10	which	which	WDT
cord-003130-p2h8p5bm	178	11	associates	associate	VBZ
cord-003130-p2h8p5bm	178	12	with	with	IN
cord-003130-p2h8p5bm	178	13	IRF9	IRF9	NNP
cord-003130-p2h8p5bm	178	14	to	to	TO
cord-003130-p2h8p5bm	178	15	form	form	VB
cord-003130-p2h8p5bm	178	16	IFN	IFN	NNP
cord-003130-p2h8p5bm	178	17	-	-	HYPH
cord-003130-p2h8p5bm	178	18	stimulated	stimulate	VBN
cord-003130-p2h8p5bm	178	19	gene	gene	NN
cord-003130-p2h8p5bm	178	20	factor-3	factor-3	NNP
cord-003130-p2h8p5bm	178	21	(	(	-LRB-
cord-003130-p2h8p5bm	178	22	ISGF3	isgf3	NN
cord-003130-p2h8p5bm	178	23	)	)	-RRB-
cord-003130-p2h8p5bm	178	24	that	that	WDT
cord-003130-p2h8p5bm	178	25	binds	bind	VBZ
cord-003130-p2h8p5bm	178	26	to	to	IN
cord-003130-p2h8p5bm	178	27	the	the	DT
cord-003130-p2h8p5bm	178	28	IFN	IFN	NNP
cord-003130-p2h8p5bm	178	29	-	-	HYPH
cord-003130-p2h8p5bm	178	30	stimulated	stimulate	VBN
cord-003130-p2h8p5bm	178	31	response	response	NN
cord-003130-p2h8p5bm	178	32	element	element	NN
cord-003130-p2h8p5bm	178	33	(	(	-LRB-
cord-003130-p2h8p5bm	178	34	ISRE	ISRE	NNP
cord-003130-p2h8p5bm	178	35	)	)	-RRB-
cord-003130-p2h8p5bm	178	36	in	in	IN
cord-003130-p2h8p5bm	178	37	the	the	DT
cord-003130-p2h8p5bm	178	38	promoter	promoter	NN
cord-003130-p2h8p5bm	178	39	of	of	IN
cord-003130-p2h8p5bm	178	40	many	many	JJ
cord-003130-p2h8p5bm	178	41	ISGs	isg	NNS
cord-003130-p2h8p5bm	178	42	to	to	TO
cord-003130-p2h8p5bm	178	43	enhance	enhance	VB
cord-003130-p2h8p5bm	178	44	the	the	DT
cord-003130-p2h8p5bm	178	45	transcription	transcription	NN
cord-003130-p2h8p5bm	178	46	of	of	IN
cord-003130-p2h8p5bm	178	47	several	several	JJ
cord-003130-p2h8p5bm	178	48	hundreds	hundred	NNS
cord-003130-p2h8p5bm	178	49	of	of	IN
cord-003130-p2h8p5bm	178	50	IFN	IFN	NNP
cord-003130-p2h8p5bm	178	51	-	-	HYPH
cord-003130-p2h8p5bm	178	52	stimulated	stimulate	VBN
cord-003130-p2h8p5bm	178	53	genes	gene	NNS
cord-003130-p2h8p5bm	178	54	[	[	-LRB-
cord-003130-p2h8p5bm	178	55	110	110	CD
cord-003130-p2h8p5bm	178	56	,	,	,
cord-003130-p2h8p5bm	178	57	139	139	CD
cord-003130-p2h8p5bm	178	58	,	,	,
cord-003130-p2h8p5bm	178	59	140	140	CD
cord-003130-p2h8p5bm	178	60	]	]	-RRB-
cord-003130-p2h8p5bm	178	61	.	.	.
cord-003130-p2h8p5bm	179	1	Together	together	RB
cord-003130-p2h8p5bm	179	2	,	,	,
cord-003130-p2h8p5bm	179	3	these	these	DT
cord-003130-p2h8p5bm	179	4	ISGs	ISGs	NNPS
cord-003130-p2h8p5bm	179	5	act	act	NNP
cord-003130-p2h8p5bm	179	6	to	to	TO
cord-003130-p2h8p5bm	179	7	coordinate	coordinate	VB
cord-003130-p2h8p5bm	179	8	an	an	DT
cord-003130-p2h8p5bm	179	9	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	179	10	response	response	NN
cord-003130-p2h8p5bm	179	11	that	that	WDT
cord-003130-p2h8p5bm	179	12	is	be	VBZ
cord-003130-p2h8p5bm	179	13	able	able	JJ
cord-003130-p2h8p5bm	179	14	to	to	TO
cord-003130-p2h8p5bm	179	15	inhibit	inhibit	VB
cord-003130-p2h8p5bm	179	16	almost	almost	RB
cord-003130-p2h8p5bm	179	17	any	any	DT
cord-003130-p2h8p5bm	179	18	step	step	NN
cord-003130-p2h8p5bm	179	19	in	in	IN
cord-003130-p2h8p5bm	179	20	the	the	DT
cord-003130-p2h8p5bm	179	21	viral	viral	JJ
cord-003130-p2h8p5bm	179	22	life	life	NN
cord-003130-p2h8p5bm	179	23	cycle	cycle	NN
cord-003130-p2h8p5bm	179	24	[	[	-LRB-
cord-003130-p2h8p5bm	179	25	140	140	CD
cord-003130-p2h8p5bm	179	26	]	]	-RRB-
cord-003130-p2h8p5bm	179	27	.	.	.
cord-003130-p2h8p5bm	180	1	The	the	DT
cord-003130-p2h8p5bm	180	2	IFN	IFN	NNP
cord-003130-p2h8p5bm	180	3	response	response	NN
cord-003130-p2h8p5bm	180	4	in	in	IN
cord-003130-p2h8p5bm	180	5	vivo	vivo	NN
cord-003130-p2h8p5bm	180	6	in	in	IN
cord-003130-p2h8p5bm	180	7	mice	mice	NN
cord-003130-p2h8p5bm	180	8	is	be	VBZ
cord-003130-p2h8p5bm	180	9	very	very	RB
cord-003130-p2h8p5bm	180	10	important	important	JJ
cord-003130-p2h8p5bm	180	11	to	to	TO
cord-003130-p2h8p5bm	180	12	protect	protect	VB
cord-003130-p2h8p5bm	180	13	mice	mouse	NNS
cord-003130-p2h8p5bm	180	14	from	from	IN
cord-003130-p2h8p5bm	180	15	lethal	lethal	JJ
cord-003130-p2h8p5bm	180	16	infection	infection	NN
cord-003130-p2h8p5bm	180	17	with	with	IN
cord-003130-p2h8p5bm	180	18	LGTV	LGTV	NNP
cord-003130-p2h8p5bm	180	19	.	.	.
cord-003130-p2h8p5bm	181	1	Mice	mouse	NNS
cord-003130-p2h8p5bm	181	2	lacking	lack	VBG
cord-003130-p2h8p5bm	181	3	IFNAR	IFNAR	NNP
cord-003130-p2h8p5bm	181	4	all	all	DT
cord-003130-p2h8p5bm	181	5	succumbed	succumb	VBD
cord-003130-p2h8p5bm	181	6	within	within	IN
cord-003130-p2h8p5bm	181	7	6	6	CD
cord-003130-p2h8p5bm	181	8	days	day	NNS
cord-003130-p2h8p5bm	181	9	of	of	IN
cord-003130-p2h8p5bm	181	10	infection	infection	NN
cord-003130-p2h8p5bm	181	11	,	,	,
cord-003130-p2h8p5bm	181	12	whereas	whereas	IN
cord-003130-p2h8p5bm	181	13	80	80	CD
cord-003130-p2h8p5bm	181	14	%	%	NN
cord-003130-p2h8p5bm	181	15	of	of	IN
cord-003130-p2h8p5bm	181	16	WT	WT	NNP
cord-003130-p2h8p5bm	181	17	mice	mouse	NNS
cord-003130-p2h8p5bm	181	18	(	(	-LRB-
cord-003130-p2h8p5bm	181	19	6	6	CD
cord-003130-p2h8p5bm	181	20	-	-	HYPH
cord-003130-p2h8p5bm	181	21	8-week	8-week	JJ
cord-003130-p2h8p5bm	181	22	-	-	HYPH
cord-003130-p2h8p5bm	181	23	old	old	JJ
cord-003130-p2h8p5bm	181	24	)	)	-RRB-
cord-003130-p2h8p5bm	181	25	survived	survive	VBD
cord-003130-p2h8p5bm	181	26	the	the	DT
cord-003130-p2h8p5bm	181	27	infection	infection	NN
cord-003130-p2h8p5bm	181	28	.	.	.
cord-003130-p2h8p5bm	182	1	Interestingly	interestingly	RB
cord-003130-p2h8p5bm	182	2	,	,	,
cord-003130-p2h8p5bm	182	3	all	all	DT
cord-003130-p2h8p5bm	182	4	IFNβ	IFNβ	NNS
cord-003130-p2h8p5bm	182	5	−/−	−/−	NNP
cord-003130-p2h8p5bm	182	6	mice	mouse	NNS
cord-003130-p2h8p5bm	182	7	survived	survive	VBD
cord-003130-p2h8p5bm	182	8	the	the	DT
cord-003130-p2h8p5bm	182	9	infection	infection	NN
cord-003130-p2h8p5bm	182	10	,	,	,
cord-003130-p2h8p5bm	182	11	demonstrating	demonstrate	VBG
cord-003130-p2h8p5bm	182	12	that	that	IN
cord-003130-p2h8p5bm	182	13	the	the	DT
cord-003130-p2h8p5bm	182	14	IFNαs	IFNαs	NNP
cord-003130-p2h8p5bm	182	15	can	can	MD
cord-003130-p2h8p5bm	182	16	compensate	compensate	VB
cord-003130-p2h8p5bm	182	17	for	for	IN
cord-003130-p2h8p5bm	182	18	loss	loss	NN
cord-003130-p2h8p5bm	182	19	of	of	IN
cord-003130-p2h8p5bm	182	20	IFNβ	IFNβ	NNS
cord-003130-p2h8p5bm	182	21	in	in	IN
cord-003130-p2h8p5bm	182	22	LGTV	LGTV	NNP
cord-003130-p2h8p5bm	182	23	infection	infection	NN
cord-003130-p2h8p5bm	182	24	.	.	.
cord-003130-p2h8p5bm	183	1	Furthermore	furthermore	RB
cord-003130-p2h8p5bm	183	2	,	,	,
cord-003130-p2h8p5bm	183	3	IFNAR	IFNAR	NNP
cord-003130-p2h8p5bm	183	4	was	be	VBD
cord-003130-p2h8p5bm	183	5	shown	show	VBN
cord-003130-p2h8p5bm	183	6	to	to	TO
cord-003130-p2h8p5bm	183	7	be	be	VB
cord-003130-p2h8p5bm	183	8	a	a	DT
cord-003130-p2h8p5bm	183	9	critical	critical	JJ
cord-003130-p2h8p5bm	183	10	determinant	determinant	NN
cord-003130-p2h8p5bm	183	11	of	of	IN
cord-003130-p2h8p5bm	183	12	LGTV	LGTV	NNP
cord-003130-p2h8p5bm	183	13	tropism	tropism	NN
cord-003130-p2h8p5bm	183	14	as	as	IN
cord-003130-p2h8p5bm	183	15	LGTV	LGTV	NNP
cord-003130-p2h8p5bm	183	16	RNA	RNA	NNP
cord-003130-p2h8p5bm	183	17	was	be	VBD
cord-003130-p2h8p5bm	183	18	found	find	VBN
cord-003130-p2h8p5bm	183	19	in	in	IN
cord-003130-p2h8p5bm	183	20	all	all	DT
cord-003130-p2h8p5bm	183	21	organs	organ	NNS
cord-003130-p2h8p5bm	183	22	in	in	IN
cord-003130-p2h8p5bm	183	23	the	the	DT
cord-003130-p2h8p5bm	183	24	absence	absence	NN
cord-003130-p2h8p5bm	183	25	of	of	IN
cord-003130-p2h8p5bm	183	26	IFNAR	IFNAR	NNP
cord-003130-p2h8p5bm	183	27	,	,	,
cord-003130-p2h8p5bm	183	28	whereas	whereas	IN
cord-003130-p2h8p5bm	183	29	in	in	IN
cord-003130-p2h8p5bm	183	30	WT	WT	NNP
cord-003130-p2h8p5bm	183	31	,	,	,
cord-003130-p2h8p5bm	183	32	only	only	RB
cord-003130-p2h8p5bm	183	33	low	low	JJ
cord-003130-p2h8p5bm	183	34	viral	viral	JJ
cord-003130-p2h8p5bm	183	35	burdens	burden	NNS
cord-003130-p2h8p5bm	183	36	can	can	MD
cord-003130-p2h8p5bm	183	37	be	be	VB
cord-003130-p2h8p5bm	183	38	detected	detect	VBN
cord-003130-p2h8p5bm	183	39	in	in	IN
cord-003130-p2h8p5bm	183	40	the	the	DT
cord-003130-p2h8p5bm	183	41	olfactory	olfactory	JJ
cord-003130-p2h8p5bm	183	42	bulb	bulb	NN
cord-003130-p2h8p5bm	183	43	[	[	-LRB-
cord-003130-p2h8p5bm	183	44	99	99	CD
cord-003130-p2h8p5bm	183	45	,	,	,
cord-003130-p2h8p5bm	183	46	128	128	CD
cord-003130-p2h8p5bm	183	47	,	,	,
cord-003130-p2h8p5bm	183	48	141	141	CD
cord-003130-p2h8p5bm	183	49	]	]	-RRB-
cord-003130-p2h8p5bm	183	50	.	.	.
cord-003130-p2h8p5bm	184	1	Using	use	VBG
cord-003130-p2h8p5bm	184	2	transgenic	transgenic	JJ
cord-003130-p2h8p5bm	184	3	mice	mouse	NNS
cord-003130-p2h8p5bm	184	4	,	,	,
cord-003130-p2h8p5bm	184	5	it	-PRON-	PRP
cord-003130-p2h8p5bm	184	6	was	be	VBD
cord-003130-p2h8p5bm	184	7	further	further	RB
cord-003130-p2h8p5bm	184	8	shown	show	VBN
cord-003130-p2h8p5bm	184	9	that	that	IN
cord-003130-p2h8p5bm	184	10	the	the	DT
cord-003130-p2h8p5bm	184	11	IFN	IFN	NNP
cord-003130-p2h8p5bm	184	12	response	response	NN
cord-003130-p2h8p5bm	184	13	was	be	VBD
cord-003130-p2h8p5bm	184	14	needed	need	VBN
cord-003130-p2h8p5bm	184	15	both	both	CC
cord-003130-p2h8p5bm	184	16	in	in	IN
cord-003130-p2h8p5bm	184	17	the	the	DT
cord-003130-p2h8p5bm	184	18	peripheral	peripheral	JJ
cord-003130-p2h8p5bm	184	19	tissue	tissue	NN
cord-003130-p2h8p5bm	184	20	,	,	,
cord-003130-p2h8p5bm	184	21	as	as	RB
cord-003130-p2h8p5bm	184	22	well	well	RB
cord-003130-p2h8p5bm	184	23	as	as	IN
cord-003130-p2h8p5bm	184	24	locally	locally	RB
cord-003130-p2h8p5bm	184	25	in	in	IN
cord-003130-p2h8p5bm	184	26	the	the	DT
cord-003130-p2h8p5bm	184	27	CNS	CNS	NNP
cord-003130-p2h8p5bm	184	28	,	,	,
cord-003130-p2h8p5bm	184	29	in	in	IN
cord-003130-p2h8p5bm	184	30	order	order	NN
cord-003130-p2h8p5bm	184	31	to	to	TO
cord-003130-p2h8p5bm	184	32	clear	clear	VB
cord-003130-p2h8p5bm	184	33	LGTV	LGTV	NNP
cord-003130-p2h8p5bm	184	34	infection	infection	NN
cord-003130-p2h8p5bm	184	35	[	[	-LRB-
cord-003130-p2h8p5bm	184	36	99	99	CD
cord-003130-p2h8p5bm	184	37	,	,	,
cord-003130-p2h8p5bm	184	38	100	100	CD
cord-003130-p2h8p5bm	184	39	]	]	-RRB-
cord-003130-p2h8p5bm	184	40	.	.	.
cord-003130-p2h8p5bm	185	1	Within	within	IN
cord-003130-p2h8p5bm	185	2	the	the	DT
cord-003130-p2h8p5bm	185	3	CNS	CNS	NNP
cord-003130-p2h8p5bm	185	4	,	,	,
cord-003130-p2h8p5bm	185	5	LGTV	LGTV	NNP
cord-003130-p2h8p5bm	185	6	mainly	mainly	RB
cord-003130-p2h8p5bm	185	7	infected	infect	VBN
cord-003130-p2h8p5bm	185	8	neurons	neuron	NNS
cord-003130-p2h8p5bm	185	9	[	[	-LRB-
cord-003130-p2h8p5bm	185	10	99	99	CD
cord-003130-p2h8p5bm	185	11	,	,	,
cord-003130-p2h8p5bm	185	12	128	128	CD
cord-003130-p2h8p5bm	185	13	]	]	-RRB-
cord-003130-p2h8p5bm	185	14	,	,	,
cord-003130-p2h8p5bm	185	15	which	which	WDT
cord-003130-p2h8p5bm	185	16	is	be	VBZ
cord-003130-p2h8p5bm	185	17	also	also	RB
cord-003130-p2h8p5bm	185	18	the	the	DT
cord-003130-p2h8p5bm	185	19	case	case	NN
cord-003130-p2h8p5bm	185	20	in	in	IN
cord-003130-p2h8p5bm	185	21	lethal	lethal	JJ
cord-003130-p2h8p5bm	185	22	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	185	23	infection	infection	NN
cord-003130-p2h8p5bm	185	24	of	of	IN
cord-003130-p2h8p5bm	185	25	humans	human	NNS
cord-003130-p2h8p5bm	185	26	[	[	-LRB-
cord-003130-p2h8p5bm	185	27	142	142	CD
cord-003130-p2h8p5bm	185	28	]	]	-RRB-
cord-003130-p2h8p5bm	185	29	.	.	.
cord-003130-p2h8p5bm	186	1	Although	although	IN
cord-003130-p2h8p5bm	186	2	neurons	neuron	NNS
cord-003130-p2h8p5bm	186	3	remain	remain	VBP
cord-003130-p2h8p5bm	186	4	the	the	DT
cord-003130-p2h8p5bm	186	5	main	main	JJ
cord-003130-p2h8p5bm	186	6	target	target	NN
cord-003130-p2h8p5bm	186	7	cell	cell	NN
cord-003130-p2h8p5bm	186	8	of	of	IN
cord-003130-p2h8p5bm	186	9	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	186	10	,	,	,
cord-003130-p2h8p5bm	186	11	astrogliosis	astrogliosis	NN
cord-003130-p2h8p5bm	186	12	have	have	VBP
cord-003130-p2h8p5bm	186	13	been	be	VBN
cord-003130-p2h8p5bm	186	14	shown	show	VBN
cord-003130-p2h8p5bm	186	15	in	in	IN
cord-003130-p2h8p5bm	186	16	post	post	FW
cord-003130-p2h8p5bm	186	17	mortem	mortem	FW
cord-003130-p2h8p5bm	186	18	human	human	JJ
cord-003130-p2h8p5bm	186	19	brains	brain	NNS
cord-003130-p2h8p5bm	186	20	[	[	-LRB-
cord-003130-p2h8p5bm	186	21	142	142	CD
cord-003130-p2h8p5bm	186	22	,	,	,
cord-003130-p2h8p5bm	186	23	143	143	CD
cord-003130-p2h8p5bm	186	24	]	]	-RRB-
cord-003130-p2h8p5bm	186	25	.	.	.
cord-003130-p2h8p5bm	187	1	In	in	IN
cord-003130-p2h8p5bm	187	2	vitro	vitro	FW
cord-003130-p2h8p5bm	187	3	studies	study	NNS
cord-003130-p2h8p5bm	187	4	on	on	IN
cord-003130-p2h8p5bm	187	5	primary	primary	JJ
cord-003130-p2h8p5bm	187	6	cortical	cortical	JJ
cord-003130-p2h8p5bm	187	7	astrocytes	astrocyte	NNS
cord-003130-p2h8p5bm	187	8	show	show	VBP
cord-003130-p2h8p5bm	187	9	a	a	DT
cord-003130-p2h8p5bm	187	10	fast	fast	JJ
cord-003130-p2h8p5bm	187	11	up	up	RP
cord-003130-p2h8p5bm	187	12	regulation	regulation	NN
cord-003130-p2h8p5bm	187	13	and	and	CC
cord-003130-p2h8p5bm	187	14	secretion	secretion	NN
cord-003130-p2h8p5bm	187	15	of	of	IN
cord-003130-p2h8p5bm	187	16	IFN	IFN	NNP
cord-003130-p2h8p5bm	187	17	after	after	IN
cord-003130-p2h8p5bm	187	18	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	187	19	infection	infection	NN
cord-003130-p2h8p5bm	187	20	,	,	,
cord-003130-p2h8p5bm	187	21	which	which	WDT
cord-003130-p2h8p5bm	187	22	is	be	VBZ
cord-003130-p2h8p5bm	187	23	able	able	JJ
cord-003130-p2h8p5bm	187	24	to	to	TO
cord-003130-p2h8p5bm	187	25	protect	protect	VB
cord-003130-p2h8p5bm	187	26	neighboring	neighboring	NN
cord-003130-p2h8p5bm	187	27	astrocytes	astrocyte	NNS
cord-003130-p2h8p5bm	187	28	and	and	CC
cord-003130-p2h8p5bm	187	29	neurons	neuron	NNS
cord-003130-p2h8p5bm	187	30	from	from	IN
cord-003130-p2h8p5bm	187	31	infection	infection	NN
cord-003130-p2h8p5bm	187	32	already	already	RB
cord-003130-p2h8p5bm	187	33	6	6	CD
cord-003130-p2h8p5bm	187	34	and	and	CC
cord-003130-p2h8p5bm	187	35	3	3	CD
cord-003130-p2h8p5bm	187	36	h	h	NN
cord-003130-p2h8p5bm	187	37	post	post	NN
cord-003130-p2h8p5bm	187	38	infection	infection	NN
cord-003130-p2h8p5bm	187	39	,	,	,
cord-003130-p2h8p5bm	187	40	respectively	respectively	RB
cord-003130-p2h8p5bm	187	41	[	[	-LRB-
cord-003130-p2h8p5bm	187	42	100	100	CD
cord-003130-p2h8p5bm	187	43	]	]	-RRB-
cord-003130-p2h8p5bm	187	44	.	.	.
cord-003130-p2h8p5bm	188	1	Astrocytes	Astrocytes	NNPS
cord-003130-p2h8p5bm	188	2	have	have	VBP
cord-003130-p2h8p5bm	188	3	been	be	VBN
cord-003130-p2h8p5bm	188	4	shown	show	VBN
cord-003130-p2h8p5bm	188	5	to	to	TO
cord-003130-p2h8p5bm	188	6	be	be	VB
cord-003130-p2h8p5bm	188	7	resistant	resistant	JJ
cord-003130-p2h8p5bm	188	8	to	to	IN
cord-003130-p2h8p5bm	188	9	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	188	10	-	-	HYPH
cord-003130-p2h8p5bm	188	11	induced	induce	VBN
cord-003130-p2h8p5bm	188	12	cytopathic	cytopathic	JJ
cord-003130-p2h8p5bm	188	13	effects	effect	NNS
cord-003130-p2h8p5bm	188	14	[	[	-LRB-
cord-003130-p2h8p5bm	188	15	144	144	CD
cord-003130-p2h8p5bm	188	16	,	,	,
cord-003130-p2h8p5bm	188	17	145	145	CD
cord-003130-p2h8p5bm	188	18	]	]	-RRB-
cord-003130-p2h8p5bm	188	19	,	,	,
cord-003130-p2h8p5bm	188	20	and	and	CC
cord-003130-p2h8p5bm	188	21	it	-PRON-	PRP
cord-003130-p2h8p5bm	188	22	was	be	VBD
cord-003130-p2h8p5bm	188	23	later	later	RB
cord-003130-p2h8p5bm	188	24	shown	show	VBN
cord-003130-p2h8p5bm	188	25	that	that	IN
cord-003130-p2h8p5bm	188	26	IFNAR	IFNAR	NNP
cord-003130-p2h8p5bm	188	27	expression	expression	NN
cord-003130-p2h8p5bm	188	28	protected	protect	VBD
cord-003130-p2h8p5bm	188	29	the	the	DT
cord-003130-p2h8p5bm	188	30	astrocytes	astrocyte	NNS
cord-003130-p2h8p5bm	188	31	from	from	IN
cord-003130-p2h8p5bm	188	32	the	the	DT
cord-003130-p2h8p5bm	188	33	virus	virus	NN
cord-003130-p2h8p5bm	188	34	-	-	HYPH
cord-003130-p2h8p5bm	188	35	induced	induce	VBN
cord-003130-p2h8p5bm	188	36	cytopathic	cytopathic	JJ
cord-003130-p2h8p5bm	188	37	effects	effect	NNS
cord-003130-p2h8p5bm	188	38	[	[	-LRB-
cord-003130-p2h8p5bm	188	39	100	100	CD
cord-003130-p2h8p5bm	188	40	]	]	-RRB-
cord-003130-p2h8p5bm	188	41	.	.	.
cord-003130-p2h8p5bm	189	1	Pretreatment	pretreatment	NN
cord-003130-p2h8p5bm	189	2	of	of	IN
cord-003130-p2h8p5bm	189	3	cells	cell	NNS
cord-003130-p2h8p5bm	189	4	with	with	IN
cord-003130-p2h8p5bm	189	5	IFNs	ifn	NNS
cord-003130-p2h8p5bm	189	6	strongly	strongly	RB
cord-003130-p2h8p5bm	189	7	inhibits	inhibit	VBZ
cord-003130-p2h8p5bm	189	8	growth	growth	NN
cord-003130-p2h8p5bm	189	9	of	of	IN
cord-003130-p2h8p5bm	189	10	most	most	JJS
cord-003130-p2h8p5bm	189	11	TBFVs	tbfv	NNS
cord-003130-p2h8p5bm	189	12	in	in	IN
cord-003130-p2h8p5bm	189	13	cell	cell	NN
cord-003130-p2h8p5bm	189	14	culture	culture	NN
cord-003130-p2h8p5bm	189	15	[	[	-LRB-
cord-003130-p2h8p5bm	189	16	100	100	CD
cord-003130-p2h8p5bm	189	17	,	,	,
cord-003130-p2h8p5bm	189	18	103	103	CD
cord-003130-p2h8p5bm	189	19	,	,	,
cord-003130-p2h8p5bm	189	20	[	[	-LRB-
cord-003130-p2h8p5bm	189	21	146	146	CD
cord-003130-p2h8p5bm	189	22	]	]	-RRB-
cord-003130-p2h8p5bm	189	23	[	[	-LRB-
cord-003130-p2h8p5bm	189	24	147	147	CD
cord-003130-p2h8p5bm	189	25	]	]	-RRB-
cord-003130-p2h8p5bm	189	26	[	[	-LRB-
cord-003130-p2h8p5bm	189	27	148	148	CD
cord-003130-p2h8p5bm	189	28	]	]	-RRB-
cord-003130-p2h8p5bm	189	29	[	[	-LRB-
cord-003130-p2h8p5bm	189	30	149	149	CD
cord-003130-p2h8p5bm	189	31	]	]	-RRB-
cord-003130-p2h8p5bm	189	32	and	and	CC
cord-003130-p2h8p5bm	189	33	this	this	DT
cord-003130-p2h8p5bm	189	34	is	be	VBZ
cord-003130-p2h8p5bm	189	35	due	due	JJ
cord-003130-p2h8p5bm	189	36	to	to	IN
cord-003130-p2h8p5bm	189	37	the	the	DT
cord-003130-p2h8p5bm	189	38	upregulation	upregulation	NN
cord-003130-p2h8p5bm	189	39	and	and	CC
cord-003130-p2h8p5bm	189	40	concerted	concerted	JJ
cord-003130-p2h8p5bm	189	41	actions	action	NNS
cord-003130-p2h8p5bm	189	42	of	of	IN
cord-003130-p2h8p5bm	189	43	several	several	JJ
cord-003130-p2h8p5bm	189	44	hundreds	hundred	NNS
cord-003130-p2h8p5bm	189	45	of	of	IN
cord-003130-p2h8p5bm	189	46	ISGs	isg	NNS
cord-003130-p2h8p5bm	189	47	.	.	.
cord-003130-p2h8p5bm	190	1	Only	only	RB
cord-003130-p2h8p5bm	190	2	a	a	DT
cord-003130-p2h8p5bm	190	3	few	few	JJ
cord-003130-p2h8p5bm	190	4	ISGs	isg	NNS
cord-003130-p2h8p5bm	190	5	have	have	VBP
cord-003130-p2h8p5bm	190	6	been	be	VBN
cord-003130-p2h8p5bm	190	7	identified	identify	VBN
cord-003130-p2h8p5bm	190	8	to	to	TO
cord-003130-p2h8p5bm	190	9	play	play	VB
cord-003130-p2h8p5bm	190	10	a	a	DT
cord-003130-p2h8p5bm	190	11	role	role	NN
cord-003130-p2h8p5bm	190	12	in	in	IN
cord-003130-p2h8p5bm	190	13	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	190	14	and	and	CC
cord-003130-p2h8p5bm	190	15	LGTV	LGTV	NNP
cord-003130-p2h8p5bm	190	16	infection	infection	NN
cord-003130-p2h8p5bm	190	17	[	[	-LRB-
cord-003130-p2h8p5bm	190	18	86	86	CD
cord-003130-p2h8p5bm	190	19	,	,	,
cord-003130-p2h8p5bm	190	20	141	141	CD
cord-003130-p2h8p5bm	190	21	,	,	,
cord-003130-p2h8p5bm	190	22	147	147	CD
cord-003130-p2h8p5bm	190	23	,	,	,
cord-003130-p2h8p5bm	190	24	149	149	CD
cord-003130-p2h8p5bm	190	25	,	,	,
cord-003130-p2h8p5bm	190	26	150	150	CD
cord-003130-p2h8p5bm	190	27	]	]	-RRB-
cord-003130-p2h8p5bm	190	28	.	.	.
cord-003130-p2h8p5bm	191	1	One	one	CD
cord-003130-p2h8p5bm	191	2	of	of	IN
cord-003130-p2h8p5bm	191	3	them	-PRON-	PRP
cord-003130-p2h8p5bm	191	4	,	,	,
cord-003130-p2h8p5bm	191	5	the	the	DT
cord-003130-p2h8p5bm	191	6	2	2	CD
cord-003130-p2h8p5bm	191	7	-5	-5	CD
cord-003130-p2h8p5bm	191	8	-oligoadenylate	-oligoadenylate	HYPH
cord-003130-p2h8p5bm	191	9	synthetase	synthetase	NN
cord-003130-p2h8p5bm	191	10	(	(	-LRB-
cord-003130-p2h8p5bm	191	11	2	2	CD
cord-003130-p2h8p5bm	191	12	-5	-5	CD
cord-003130-p2h8p5bm	191	13	-OAS	-oas	ADD
cord-003130-p2h8p5bm	191	14	)	)	-RRB-
cord-003130-p2h8p5bm	192	1	(	(	-LRB-
cord-003130-p2h8p5bm	192	2	OAS	OAS	NNP
cord-003130-p2h8p5bm	192	3	)	)	-RRB-
cord-003130-p2h8p5bm	192	4	is	be	VBZ
cord-003130-p2h8p5bm	192	5	activated	activate	VBN
cord-003130-p2h8p5bm	192	6	by	by	IN
cord-003130-p2h8p5bm	192	7	double	double	RB
cord-003130-p2h8p5bm	192	8	-	-	HYPH
cord-003130-p2h8p5bm	192	9	stranded	strand	VBN
cord-003130-p2h8p5bm	192	10	RNA	RNA	NNP
cord-003130-p2h8p5bm	192	11	,	,	,
cord-003130-p2h8p5bm	192	12	leading	lead	VBG
cord-003130-p2h8p5bm	192	13	to	to	IN
cord-003130-p2h8p5bm	192	14	the	the	DT
cord-003130-p2h8p5bm	192	15	OAS	OAS	NNP
cord-003130-p2h8p5bm	192	16	protein	protein	NN
cord-003130-p2h8p5bm	192	17	polymerization	polymerization	NN
cord-003130-p2h8p5bm	192	18	into	into	IN
cord-003130-p2h8p5bm	192	19	2	2	CD
cord-003130-p2h8p5bm	193	1	-5	-5	NNP
cord-003130-p2h8p5bm	193	2	-linked	-linked	JJ
cord-003130-p2h8p5bm	193	3	oligoadenylates	oligoadenylate	NNS
cord-003130-p2h8p5bm	193	4	(	(	-LRB-
cord-003130-p2h8p5bm	193	5	2	2	CD
cord-003130-p2h8p5bm	193	6	-	-	HYPH
cord-003130-p2h8p5bm	193	7	5As	5as	JJ
cord-003130-p2h8p5bm	193	8	)	)	-RRB-
cord-003130-p2h8p5bm	194	1	[	[	-LRB-
cord-003130-p2h8p5bm	194	2	151	151	CD
cord-003130-p2h8p5bm	194	3	,	,	,
cord-003130-p2h8p5bm	194	4	152	152	CD
cord-003130-p2h8p5bm	194	5	]	]	-RRB-
cord-003130-p2h8p5bm	194	6	.	.	.
cord-003130-p2h8p5bm	195	1	These	these	DT
cord-003130-p2h8p5bm	195	2	2	2	CD
cord-003130-p2h8p5bm	195	3	-	-	HYPH
cord-003130-p2h8p5bm	195	4	5As	5as	JJ
cord-003130-p2h8p5bm	195	5	activate	activate	VB
cord-003130-p2h8p5bm	195	6	RNase	RNase	NNP
cord-003130-p2h8p5bm	195	7	L	L	NNP
cord-003130-p2h8p5bm	195	8	,	,	,
cord-003130-p2h8p5bm	195	9	resulting	result	VBG
cord-003130-p2h8p5bm	195	10	in	in	IN
cord-003130-p2h8p5bm	195	11	the	the	DT
cord-003130-p2h8p5bm	195	12	degradation	degradation	NN
cord-003130-p2h8p5bm	195	13	of	of	IN
cord-003130-p2h8p5bm	195	14	viral	viral	JJ
cord-003130-p2h8p5bm	195	15	RNA	RNA	NNP
cord-003130-p2h8p5bm	195	16	[	[	-LRB-
cord-003130-p2h8p5bm	195	17	153	153	CD
cord-003130-p2h8p5bm	195	18	]	]	-RRB-
cord-003130-p2h8p5bm	195	19	.	.	.
cord-003130-p2h8p5bm	196	1	Several	several	JJ
cord-003130-p2h8p5bm	196	2	polymorphisms	polymorphism	NNS
cord-003130-p2h8p5bm	196	3	in	in	IN
cord-003130-p2h8p5bm	196	4	the	the	DT
cord-003130-p2h8p5bm	196	5	OAS	OAS	NNP
cord-003130-p2h8p5bm	196	6	genes	gene	NNS
cord-003130-p2h8p5bm	196	7	have	have	VBP
cord-003130-p2h8p5bm	196	8	been	be	VBN
cord-003130-p2h8p5bm	196	9	shown	show	VBN
cord-003130-p2h8p5bm	196	10	to	to	TO
cord-003130-p2h8p5bm	196	11	correlate	correlate	VB
cord-003130-p2h8p5bm	196	12	with	with	IN
cord-003130-p2h8p5bm	196	13	severe	severe	JJ
cord-003130-p2h8p5bm	196	14	forms	form	NNS
cord-003130-p2h8p5bm	196	15	of	of	IN
cord-003130-p2h8p5bm	196	16	TBE	tbe	NN
cord-003130-p2h8p5bm	196	17	in	in	IN
cord-003130-p2h8p5bm	196	18	patients	patient	NNS
cord-003130-p2h8p5bm	196	19	[	[	-LRB-
cord-003130-p2h8p5bm	196	20	154	154	CD
cord-003130-p2h8p5bm	196	21	]	]	-RRB-
cord-003130-p2h8p5bm	196	22	.	.	.
cord-003130-p2h8p5bm	197	1	Also	also	RB
cord-003130-p2h8p5bm	197	2	,	,	,
cord-003130-p2h8p5bm	197	3	the	the	DT
cord-003130-p2h8p5bm	197	4	murine	murine	JJ
cord-003130-p2h8p5bm	197	5	isoform	isoform	NN
cord-003130-p2h8p5bm	197	6	Oas1b	Oas1b	NNP
cord-003130-p2h8p5bm	197	7	,	,	,
cord-003130-p2h8p5bm	197	8	which	which	WDT
cord-003130-p2h8p5bm	197	9	is	be	VBZ
cord-003130-p2h8p5bm	197	10	often	often	RB
cord-003130-p2h8p5bm	197	11	lacking	lack	VBG
cord-003130-p2h8p5bm	197	12	in	in	IN
cord-003130-p2h8p5bm	197	13	inbred	inbred	JJ
cord-003130-p2h8p5bm	197	14	mice	mice	NN
cord-003130-p2h8p5bm	197	15	strains	strain	NNS
cord-003130-p2h8p5bm	197	16	,	,	,
cord-003130-p2h8p5bm	197	17	confers	confer	VBZ
cord-003130-p2h8p5bm	197	18	strain	strain	NN
cord-003130-p2h8p5bm	197	19	dependent	dependent	JJ
cord-003130-p2h8p5bm	197	20	resistance	resistance	NN
cord-003130-p2h8p5bm	197	21	against	against	IN
cord-003130-p2h8p5bm	197	22	neurovirulence	neurovirulence	NNP
cord-003130-p2h8p5bm	197	23	from	from	IN
cord-003130-p2h8p5bm	197	24	far	far	JJ
cord-003130-p2h8p5bm	197	25	eastern	eastern	JJ
cord-003130-p2h8p5bm	197	26	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	197	27	[	[	-LRB-
cord-003130-p2h8p5bm	197	28	155	155	CD
cord-003130-p2h8p5bm	197	29	]	]	-RRB-
cord-003130-p2h8p5bm	197	30	.	.	.
cord-003130-p2h8p5bm	198	1	Two	two	CD
cord-003130-p2h8p5bm	198	2	other	other	JJ
cord-003130-p2h8p5bm	198	3	ISGs	isg	NNS
cord-003130-p2h8p5bm	198	4	which	which	WDT
cord-003130-p2h8p5bm	198	5	have	have	VBP
cord-003130-p2h8p5bm	198	6	been	be	VBN
cord-003130-p2h8p5bm	198	7	shown	show	VBN
cord-003130-p2h8p5bm	198	8	to	to	TO
cord-003130-p2h8p5bm	198	9	be	be	VB
cord-003130-p2h8p5bm	198	10	antivirally	antivirally	RB
cord-003130-p2h8p5bm	198	11	active	active	JJ
cord-003130-p2h8p5bm	198	12	against	against	IN
cord-003130-p2h8p5bm	198	13	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	198	14	are	be	VBP
cord-003130-p2h8p5bm	198	15	virus	virus	NN
cord-003130-p2h8p5bm	198	16	inhibitory	inhibitory	JJ
cord-003130-p2h8p5bm	198	17	protein	protein	NN
cord-003130-p2h8p5bm	198	18	endoplasmic	endoplasmic	NN
cord-003130-p2h8p5bm	198	19	reticulum	reticulum	NN
cord-003130-p2h8p5bm	198	20	associated	associate	VBD
cord-003130-p2h8p5bm	198	21	interferon	interferon	NN
cord-003130-p2h8p5bm	198	22	inducible	inducible	JJ
cord-003130-p2h8p5bm	198	23	(	(	-LRB-
cord-003130-p2h8p5bm	198	24	viperin	viperin	NNP
cord-003130-p2h8p5bm	198	25	)	)	-RRB-
cord-003130-p2h8p5bm	198	26	and	and	CC
cord-003130-p2h8p5bm	198	27	tripartite	tripartite	JJ
cord-003130-p2h8p5bm	198	28	motif-79α	motif-79α	NNP
cord-003130-p2h8p5bm	199	1	(	(	-LRB-
cord-003130-p2h8p5bm	199	2	TRIM79α	TRIM79α	NNP
cord-003130-p2h8p5bm	199	3	)	)	-RRB-
cord-003130-p2h8p5bm	199	4	.	.	.
cord-003130-p2h8p5bm	200	1	The	the	DT
cord-003130-p2h8p5bm	200	2	TRIM	trim	NN
cord-003130-p2h8p5bm	200	3	proteins	protein	NNS
cord-003130-p2h8p5bm	200	4	are	be	VBP
cord-003130-p2h8p5bm	200	5	a	a	DT
cord-003130-p2h8p5bm	200	6	family	family	NN
cord-003130-p2h8p5bm	200	7	of	of	IN
cord-003130-p2h8p5bm	200	8	proteins	protein	NNS
cord-003130-p2h8p5bm	200	9	able	able	JJ
cord-003130-p2h8p5bm	200	10	to	to	TO
cord-003130-p2h8p5bm	200	11	mediate	mediate	VB
cord-003130-p2h8p5bm	200	12	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	200	13	activity	activity	NN
cord-003130-p2h8p5bm	200	14	against	against	IN
cord-003130-p2h8p5bm	200	15	many	many	JJ
cord-003130-p2h8p5bm	200	16	different	different	JJ
cord-003130-p2h8p5bm	200	17	viruses	virus	NNS
cord-003130-p2h8p5bm	200	18	[	[	-LRB-
cord-003130-p2h8p5bm	200	19	156	156	CD
cord-003130-p2h8p5bm	200	20	]	]	-RRB-
cord-003130-p2h8p5bm	200	21	.	.	.
cord-003130-p2h8p5bm	201	1	The	the	DT
cord-003130-p2h8p5bm	201	2	rodent	rodent	NN
cord-003130-p2h8p5bm	201	3	specific	specific	JJ
cord-003130-p2h8p5bm	201	4	TRIM79α	trim79α	NN
cord-003130-p2h8p5bm	201	5	was	be	VBD
cord-003130-p2h8p5bm	201	6	identified	identify	VBN
cord-003130-p2h8p5bm	201	7	to	to	TO
cord-003130-p2h8p5bm	201	8	interact	interact	VB
cord-003130-p2h8p5bm	201	9	with	with	IN
cord-003130-p2h8p5bm	201	10	LGTV	LGTV	NNP
cord-003130-p2h8p5bm	201	11	NS5	ns5	JJ
cord-003130-p2h8p5bm	201	12	in	in	IN
cord-003130-p2h8p5bm	201	13	a	a	DT
cord-003130-p2h8p5bm	201	14	yeast	yeast	NN
cord-003130-p2h8p5bm	201	15	two	two	CD
cord-003130-p2h8p5bm	201	16	-	-	HYPH
cord-003130-p2h8p5bm	201	17	hybrid	hybrid	NN
cord-003130-p2h8p5bm	201	18	screen	screen	NN
cord-003130-p2h8p5bm	201	19	.	.	.
cord-003130-p2h8p5bm	202	1	TRIM79α	trim79α	JJ
cord-003130-p2h8p5bm	202	2	expression	expression	NN
cord-003130-p2h8p5bm	202	3	inhibited	inhibit	VBD
cord-003130-p2h8p5bm	202	4	viral	viral	JJ
cord-003130-p2h8p5bm	202	5	infection	infection	NN
cord-003130-p2h8p5bm	202	6	of	of	IN
cord-003130-p2h8p5bm	202	7	LGTV	LGTV	NNP
cord-003130-p2h8p5bm	202	8	and	and	CC
cord-003130-p2h8p5bm	202	9	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	202	10	by	by	IN
cord-003130-p2h8p5bm	202	11	mediating	mediate	VBG
cord-003130-p2h8p5bm	202	12	lysosomal	lysosomal	JJ
cord-003130-p2h8p5bm	202	13	dependent	dependent	JJ
cord-003130-p2h8p5bm	202	14	degradation	degradation	NN
cord-003130-p2h8p5bm	202	15	of	of	IN
cord-003130-p2h8p5bm	202	16	NS5	NS5	NNP
cord-003130-p2h8p5bm	202	17	.	.	.
cord-003130-p2h8p5bm	203	1	Interestingly	interestingly	RB
cord-003130-p2h8p5bm	203	2	this	this	DT
cord-003130-p2h8p5bm	203	3	mechanism	mechanism	NN
cord-003130-p2h8p5bm	203	4	was	be	VBD
cord-003130-p2h8p5bm	203	5	quite	quite	RB
cord-003130-p2h8p5bm	203	6	specific	specific	JJ
cord-003130-p2h8p5bm	203	7	to	to	TO
cord-003130-p2h8p5bm	203	8	tick	tick	VB
cord-003130-p2h8p5bm	203	9	-	-	HYPH
cord-003130-p2h8p5bm	203	10	borne	bear	VBN
cord-003130-p2h8p5bm	203	11	flaviviruses	flavivirus	NNS
cord-003130-p2h8p5bm	203	12	as	as	IN
cord-003130-p2h8p5bm	203	13	the	the	DT
cord-003130-p2h8p5bm	203	14	mosquito	mosquito	NN
cord-003130-p2h8p5bm	203	15	borne	bear	VBN
cord-003130-p2h8p5bm	204	1	WNV	WNV	NNP
cord-003130-p2h8p5bm	204	2	was	be	VBD
cord-003130-p2h8p5bm	204	3	not	not	RB
cord-003130-p2h8p5bm	204	4	inhibited	inhibit	VBN
cord-003130-p2h8p5bm	204	5	by	by	IN
cord-003130-p2h8p5bm	204	6	TRIM79α	trim79α	NN
cord-003130-p2h8p5bm	204	7	nor	nor	CC
cord-003130-p2h8p5bm	204	8	did	do	VBD
cord-003130-p2h8p5bm	204	9	TRIM79α	trim79α	RB
cord-003130-p2h8p5bm	204	10	interact	interact	VB
cord-003130-p2h8p5bm	204	11	with	with	IN
cord-003130-p2h8p5bm	204	12	NS5	ns5	JJ
cord-003130-p2h8p5bm	204	13	of	of	IN
cord-003130-p2h8p5bm	204	14	WNV	WNV	NNP
cord-003130-p2h8p5bm	204	15	[	[	-LRB-
cord-003130-p2h8p5bm	204	16	147	147	CD
cord-003130-p2h8p5bm	204	17	]	]	-RRB-
cord-003130-p2h8p5bm	204	18	.	.	.
cord-003130-p2h8p5bm	205	1	Viperin	Viperin	NNP
cord-003130-p2h8p5bm	205	2	is	be	VBZ
cord-003130-p2h8p5bm	205	3	highly	highly	RB
cord-003130-p2h8p5bm	205	4	conserved	conserve	VBN
cord-003130-p2h8p5bm	205	5	in	in	IN
cord-003130-p2h8p5bm	205	6	evolution	evolution	NN
cord-003130-p2h8p5bm	205	7	and	and	CC
cord-003130-p2h8p5bm	205	8	was	be	VBD
cord-003130-p2h8p5bm	205	9	first	first	RB
cord-003130-p2h8p5bm	205	10	identified	identify	VBN
cord-003130-p2h8p5bm	205	11	as	as	IN
cord-003130-p2h8p5bm	205	12	an	an	DT
cord-003130-p2h8p5bm	205	13	IFN	IFN	NNP
cord-003130-p2h8p5bm	205	14	-	-	HYPH
cord-003130-p2h8p5bm	205	15	inducible	inducible	JJ
cord-003130-p2h8p5bm	205	16	protein	protein	NN
cord-003130-p2h8p5bm	205	17	with	with	IN
cord-003130-p2h8p5bm	205	18	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	205	19	activity	activity	NN
cord-003130-p2h8p5bm	205	20	against	against	IN
cord-003130-p2h8p5bm	205	21	human	human	JJ
cord-003130-p2h8p5bm	205	22	cytomegalovirus	cytomegalovirus	NN
cord-003130-p2h8p5bm	205	23	in	in	IN
cord-003130-p2h8p5bm	205	24	2001	2001	CD
cord-003130-p2h8p5bm	205	25	[	[	-LRB-
cord-003130-p2h8p5bm	205	26	157	157	CD
cord-003130-p2h8p5bm	205	27	]	]	-RRB-
cord-003130-p2h8p5bm	205	28	.	.	.
cord-003130-p2h8p5bm	206	1	Over	over	IN
cord-003130-p2h8p5bm	206	2	the	the	DT
cord-003130-p2h8p5bm	206	3	last	last	JJ
cord-003130-p2h8p5bm	206	4	17	17	CD
cord-003130-p2h8p5bm	206	5	years	year	NNS
cord-003130-p2h8p5bm	206	6	,	,	,
cord-003130-p2h8p5bm	206	7	viperin	viperin	NNP
cord-003130-p2h8p5bm	206	8	has	have	VBZ
cord-003130-p2h8p5bm	206	9	gained	gain	VBN
cord-003130-p2h8p5bm	206	10	lot	lot	NN
cord-003130-p2h8p5bm	206	11	of	of	IN
cord-003130-p2h8p5bm	206	12	attention	attention	NN
cord-003130-p2h8p5bm	206	13	and	and	CC
cord-003130-p2h8p5bm	206	14	was	be	VBD
cord-003130-p2h8p5bm	206	15	shown	show	VBN
cord-003130-p2h8p5bm	206	16	to	to	TO
cord-003130-p2h8p5bm	206	17	exhibit	exhibit	VB
cord-003130-p2h8p5bm	206	18	broad	broad	JJ
cord-003130-p2h8p5bm	206	19	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	206	20	activity	activity	NN
cord-003130-p2h8p5bm	206	21	[	[	-LRB-
cord-003130-p2h8p5bm	206	22	158	158	CD
cord-003130-p2h8p5bm	206	23	]	]	-RRB-
cord-003130-p2h8p5bm	206	24	.	.	.
cord-003130-p2h8p5bm	207	1	Viperin	Viperin	NNP
cord-003130-p2h8p5bm	207	2	is	be	VBZ
cord-003130-p2h8p5bm	207	3	also	also	RB
cord-003130-p2h8p5bm	207	4	known	know	VBN
cord-003130-p2h8p5bm	207	5	as	as	IN
cord-003130-p2h8p5bm	207	6	one	one	CD
cord-003130-p2h8p5bm	207	7	of	of	IN
cord-003130-p2h8p5bm	207	8	the	the	DT
cord-003130-p2h8p5bm	207	9	most	most	RBS
cord-003130-p2h8p5bm	207	10	highly	highly	RB
cord-003130-p2h8p5bm	207	11	upregulated	upregulate	VBN
cord-003130-p2h8p5bm	207	12	genes	gene	NNS
cord-003130-p2h8p5bm	207	13	after	after	IN
cord-003130-p2h8p5bm	207	14	viral	viral	JJ
cord-003130-p2h8p5bm	207	15	infection	infection	NN
cord-003130-p2h8p5bm	207	16	[	[	-LRB-
cord-003130-p2h8p5bm	207	17	146	146	CD
cord-003130-p2h8p5bm	207	18	,	,	,
cord-003130-p2h8p5bm	207	19	159	159	CD
cord-003130-p2h8p5bm	207	20	]	]	-RRB-
cord-003130-p2h8p5bm	207	21	.	.	.
cord-003130-p2h8p5bm	208	1	Within	within	IN
cord-003130-p2h8p5bm	208	2	the	the	DT
cord-003130-p2h8p5bm	208	3	family	family	NN
cord-003130-p2h8p5bm	208	4	of	of	IN
cord-003130-p2h8p5bm	208	5	flaviviridae	flaviviridae	NNP
cord-003130-p2h8p5bm	208	6	,	,	,
cord-003130-p2h8p5bm	208	7	viperin	viperin	NNP
cord-003130-p2h8p5bm	208	8	has	have	VBZ
cord-003130-p2h8p5bm	208	9	been	be	VBN
cord-003130-p2h8p5bm	208	10	shown	show	VBN
cord-003130-p2h8p5bm	208	11	to	to	TO
cord-003130-p2h8p5bm	208	12	inhibit	inhibit	VB
cord-003130-p2h8p5bm	208	13	several	several	JJ
cord-003130-p2h8p5bm	208	14	members	member	NNS
cord-003130-p2h8p5bm	208	15	,	,	,
cord-003130-p2h8p5bm	208	16	such	such	JJ
cord-003130-p2h8p5bm	208	17	as	as	IN
cord-003130-p2h8p5bm	208	18	WNV	WNV	NNP
cord-003130-p2h8p5bm	208	19	[	[	-LRB-
cord-003130-p2h8p5bm	208	20	160	160	CD
cord-003130-p2h8p5bm	208	21	]	]	-RRB-
cord-003130-p2h8p5bm	208	22	,	,	,
cord-003130-p2h8p5bm	208	23	DENV	DENV	NNP
cord-003130-p2h8p5bm	208	24	[	[	-LRB-
cord-003130-p2h8p5bm	208	25	161	161	CD
cord-003130-p2h8p5bm	208	26	]	]	-RRB-
cord-003130-p2h8p5bm	208	27	,	,	,
cord-003130-p2h8p5bm	208	28	ZIKV	ZIKV	NNP
cord-003130-p2h8p5bm	208	29	[	[	-LRB-
cord-003130-p2h8p5bm	208	30	162	162	CD
cord-003130-p2h8p5bm	208	31	]	]	-RRB-
cord-003130-p2h8p5bm	208	32	,	,	,
cord-003130-p2h8p5bm	208	33	hepatitis	hepatitis	NN
cord-003130-p2h8p5bm	208	34	C	C	NNP
cord-003130-p2h8p5bm	208	35	virus	virus	NN
cord-003130-p2h8p5bm	208	36	[	[	-LRB-
cord-003130-p2h8p5bm	208	37	163	163	CD
cord-003130-p2h8p5bm	208	38	]	]	-RRB-
cord-003130-p2h8p5bm	208	39	,	,	,
cord-003130-p2h8p5bm	208	40	and	and	CC
cord-003130-p2h8p5bm	208	41	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	208	42	[	[	-LRB-
cord-003130-p2h8p5bm	208	43	86	86	CD
cord-003130-p2h8p5bm	208	44	,	,	,
cord-003130-p2h8p5bm	208	45	141	141	CD
cord-003130-p2h8p5bm	208	46	,	,	,
cord-003130-p2h8p5bm	208	47	149	149	CD
cord-003130-p2h8p5bm	208	48	,	,	,
cord-003130-p2h8p5bm	208	49	150	150	CD
cord-003130-p2h8p5bm	208	50	]	]	-RRB-
cord-003130-p2h8p5bm	208	51	.	.	.
cord-003130-p2h8p5bm	209	1	Viperin	Viperin	NNP
cord-003130-p2h8p5bm	209	2	is	be	VBZ
cord-003130-p2h8p5bm	209	3	an	an	DT
cord-003130-p2h8p5bm	209	4	iron	iron	NN
cord-003130-p2h8p5bm	209	5	sulphur	sulphur	NN
cord-003130-p2h8p5bm	209	6	protein	protein	NN
cord-003130-p2h8p5bm	209	7	with	with	IN
cord-003130-p2h8p5bm	209	8	three	three	CD
cord-003130-p2h8p5bm	209	9	domains	domain	NNS
cord-003130-p2h8p5bm	209	10	;	;	:
cord-003130-p2h8p5bm	209	11	a	a	DT
cord-003130-p2h8p5bm	209	12	N	n	CD
cord-003130-p2h8p5bm	209	13	-	-	HYPH
cord-003130-p2h8p5bm	209	14	terminus	terminus	NN
cord-003130-p2h8p5bm	209	15	amphipathic	amphipathic	NNP
cord-003130-p2h8p5bm	209	16	alpha	alpha	NN
cord-003130-p2h8p5bm	209	17	-	-	HYPH
cord-003130-p2h8p5bm	209	18	helix	helix	NNP
cord-003130-p2h8p5bm	209	19	which	which	WDT
cord-003130-p2h8p5bm	209	20	mediates	mediate	VBZ
cord-003130-p2h8p5bm	209	21	the	the	DT
cord-003130-p2h8p5bm	209	22	intracellular	intracellular	JJ
cord-003130-p2h8p5bm	209	23	localization	localization	NN
cord-003130-p2h8p5bm	209	24	to	to	IN
cord-003130-p2h8p5bm	209	25	the	the	DT
cord-003130-p2h8p5bm	209	26	ER	ER	NNP
cord-003130-p2h8p5bm	209	27	,	,	,
cord-003130-p2h8p5bm	209	28	a	a	DT
cord-003130-p2h8p5bm	209	29	S	s	NN
cord-003130-p2h8p5bm	209	30	-	-	HYPH
cord-003130-p2h8p5bm	209	31	adenosylmethionine	adenosylmethionine	NN
cord-003130-p2h8p5bm	209	32	(	(	-LRB-
cord-003130-p2h8p5bm	209	33	SAM	SAM	NNP
cord-003130-p2h8p5bm	209	34	)	)	-RRB-
cord-003130-p2h8p5bm	209	35	radical	radical	JJ
cord-003130-p2h8p5bm	209	36	domain	domain	NN
cord-003130-p2h8p5bm	209	37	[	[	-LRB-
cord-003130-p2h8p5bm	209	38	158	158	CD
cord-003130-p2h8p5bm	209	39	,	,	,
cord-003130-p2h8p5bm	209	40	164	164	CD
cord-003130-p2h8p5bm	209	41	,	,	,
cord-003130-p2h8p5bm	209	42	165	165	CD
cord-003130-p2h8p5bm	209	43	]	]	-RRB-
cord-003130-p2h8p5bm	209	44	homologous	homologous	JJ
cord-003130-p2h8p5bm	209	45	to	to	IN
cord-003130-p2h8p5bm	209	46	a	a	DT
cord-003130-p2h8p5bm	209	47	family	family	NN
cord-003130-p2h8p5bm	209	48	of	of	IN
cord-003130-p2h8p5bm	209	49	proteins	protein	NNS
cord-003130-p2h8p5bm	209	50	that	that	WDT
cord-003130-p2h8p5bm	209	51	use	use	VBP
cord-003130-p2h8p5bm	209	52	SAM	SAM	NNP
cord-003130-p2h8p5bm	209	53	as	as	IN
cord-003130-p2h8p5bm	209	54	a	a	DT
cord-003130-p2h8p5bm	209	55	cofactor	cofactor	NN
cord-003130-p2h8p5bm	209	56	[	[	-LRB-
cord-003130-p2h8p5bm	209	57	166	166	CD
cord-003130-p2h8p5bm	209	58	]	]	-RRB-
cord-003130-p2h8p5bm	209	59	,	,	,
cord-003130-p2h8p5bm	209	60	and	and	CC
cord-003130-p2h8p5bm	209	61	a	a	DT
cord-003130-p2h8p5bm	209	62	highly	highly	RB
cord-003130-p2h8p5bm	209	63	conserved	conserve	VBN
cord-003130-p2h8p5bm	209	64	C	c	NN
cord-003130-p2h8p5bm	209	65	-	-	HYPH
cord-003130-p2h8p5bm	209	66	terminal	terminal	NN
cord-003130-p2h8p5bm	209	67	domain	domain	NN
cord-003130-p2h8p5bm	209	68	,	,	,
cord-003130-p2h8p5bm	209	69	important	important	JJ
cord-003130-p2h8p5bm	209	70	for	for	IN
cord-003130-p2h8p5bm	209	71	iron	iron	NN
cord-003130-p2h8p5bm	209	72	sulphur	sulphur	NN
cord-003130-p2h8p5bm	209	73	(	(	-LRB-
cord-003130-p2h8p5bm	209	74	Fe	Fe	NNP
cord-003130-p2h8p5bm	209	75	/	/	SYM
cord-003130-p2h8p5bm	209	76	S	S	NNP
cord-003130-p2h8p5bm	209	77	)	)	-RRB-
cord-003130-p2h8p5bm	209	78	maturation	maturation	NN
cord-003130-p2h8p5bm	209	79	[	[	-LRB-
cord-003130-p2h8p5bm	209	80	149	149	CD
cord-003130-p2h8p5bm	209	81	,	,	,
cord-003130-p2h8p5bm	209	82	167	167	CD
cord-003130-p2h8p5bm	209	83	]	]	-RRB-
cord-003130-p2h8p5bm	209	84	.	.	.
cord-003130-p2h8p5bm	210	1	Although	although	IN
cord-003130-p2h8p5bm	210	2	viperin	viperin	NNP
cord-003130-p2h8p5bm	210	3	is	be	VBZ
cord-003130-p2h8p5bm	210	4	able	able	JJ
cord-003130-p2h8p5bm	210	5	to	to	TO
cord-003130-p2h8p5bm	210	6	inhibit	inhibit	VB
cord-003130-p2h8p5bm	210	7	several	several	JJ
cord-003130-p2h8p5bm	210	8	different	different	JJ
cord-003130-p2h8p5bm	210	9	viruses	virus	NNS
cord-003130-p2h8p5bm	210	10	,	,	,
cord-003130-p2h8p5bm	210	11	the	the	DT
cord-003130-p2h8p5bm	210	12	mechanism	mechanism	NN
cord-003130-p2h8p5bm	210	13	of	of	IN
cord-003130-p2h8p5bm	210	14	action	action	NN
cord-003130-p2h8p5bm	210	15	,	,	,
cord-003130-p2h8p5bm	210	16	the	the	DT
cord-003130-p2h8p5bm	210	17	important	important	JJ
cord-003130-p2h8p5bm	210	18	motif	motif	NN
cord-003130-p2h8p5bm	210	19	in	in	IN
cord-003130-p2h8p5bm	210	20	viperin	viperin	NNP
cord-003130-p2h8p5bm	210	21	and	and	CC
cord-003130-p2h8p5bm	210	22	the	the	DT
cord-003130-p2h8p5bm	210	23	step	step	NN
cord-003130-p2h8p5bm	210	24	of	of	IN
cord-003130-p2h8p5bm	210	25	viral	viral	JJ
cord-003130-p2h8p5bm	210	26	life	life	NN
cord-003130-p2h8p5bm	210	27	cycle	cycle	NN
cord-003130-p2h8p5bm	210	28	inhibited	inhibit	VBN
cord-003130-p2h8p5bm	210	29	differs	differ	VBZ
cord-003130-p2h8p5bm	210	30	for	for	IN
cord-003130-p2h8p5bm	210	31	different	different	JJ
cord-003130-p2h8p5bm	210	32	viruses	virus	NNS
cord-003130-p2h8p5bm	210	33	[	[	-LRB-
cord-003130-p2h8p5bm	210	34	158	158	CD
cord-003130-p2h8p5bm	210	35	]	]	-RRB-
cord-003130-p2h8p5bm	210	36	.	.	.
cord-003130-p2h8p5bm	211	1	Viperin	Viperin	NNP
cord-003130-p2h8p5bm	211	2	interacts	interact	VBZ
cord-003130-p2h8p5bm	211	3	with	with	IN
cord-003130-p2h8p5bm	211	4	many	many	JJ
cord-003130-p2h8p5bm	211	5	viral	viral	JJ
cord-003130-p2h8p5bm	211	6	and	and	CC
cord-003130-p2h8p5bm	211	7	host	host	NN
cord-003130-p2h8p5bm	211	8	factors	factor	NNS
cord-003130-p2h8p5bm	211	9	for	for	IN
cord-003130-p2h8p5bm	211	10	its	-PRON-	PRP$
cord-003130-p2h8p5bm	211	11	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	211	12	function	function	NN
cord-003130-p2h8p5bm	211	13	.	.	.
cord-003130-p2h8p5bm	212	1	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	212	2	replication	replication	NN
cord-003130-p2h8p5bm	212	3	is	be	VBZ
cord-003130-p2h8p5bm	212	4	strongly	strongly	RB
cord-003130-p2h8p5bm	212	5	inhibited	inhibit	VBN
cord-003130-p2h8p5bm	212	6	by	by	IN
cord-003130-p2h8p5bm	212	7	viperin	viperin	NNP
cord-003130-p2h8p5bm	212	8	,	,	,
cord-003130-p2h8p5bm	212	9	our	-PRON-	PRP$
cord-003130-p2h8p5bm	212	10	research	research	NN
cord-003130-p2h8p5bm	212	11	shows	show	VBZ
cord-003130-p2h8p5bm	212	12	that	that	IN
cord-003130-p2h8p5bm	212	13	viperin	viperin	NNP
cord-003130-p2h8p5bm	212	14	has	have	VBZ
cord-003130-p2h8p5bm	212	15	no	no	DT
cord-003130-p2h8p5bm	212	16	effect	effect	NN
cord-003130-p2h8p5bm	212	17	on	on	IN
cord-003130-p2h8p5bm	212	18	the	the	DT
cord-003130-p2h8p5bm	212	19	binding	binding	NN
cord-003130-p2h8p5bm	212	20	or	or	CC
cord-003130-p2h8p5bm	212	21	entry	entry	NN
cord-003130-p2h8p5bm	212	22	of	of	IN
cord-003130-p2h8p5bm	212	23	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	212	24	.	.	.
cord-003130-p2h8p5bm	213	1	However	however	RB
cord-003130-p2h8p5bm	213	2	,	,	,
cord-003130-p2h8p5bm	213	3	viperin	viperin	NNP
cord-003130-p2h8p5bm	213	4	targets	target	NNS
cord-003130-p2h8p5bm	213	5	genome	genome	NN
cord-003130-p2h8p5bm	213	6	replication	replication	NN
cord-003130-p2h8p5bm	213	7	,	,	,
cord-003130-p2h8p5bm	213	8	packaging	packaging	NN
cord-003130-p2h8p5bm	213	9	,	,	,
cord-003130-p2h8p5bm	213	10	and	and	CC
cord-003130-p2h8p5bm	213	11	release	release	NN
cord-003130-p2h8p5bm	213	12	of	of	IN
cord-003130-p2h8p5bm	213	13	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	213	14	(	(	-LRB-
cord-003130-p2h8p5bm	213	15	Figure	figure	NN
cord-003130-p2h8p5bm	213	16	3	3	CD
cord-003130-p2h8p5bm	213	17	)	)	-RRB-
cord-003130-p2h8p5bm	213	18	[	[	-LRB-
cord-003130-p2h8p5bm	213	19	86	86	CD
cord-003130-p2h8p5bm	213	20	,	,	,
cord-003130-p2h8p5bm	213	21	149	149	CD
cord-003130-p2h8p5bm	213	22	,	,	,
cord-003130-p2h8p5bm	213	23	150	150	CD
cord-003130-p2h8p5bm	213	24	]	]	-RRB-
cord-003130-p2h8p5bm	213	25	.	.	.
cord-003130-p2h8p5bm	214	1	Viperin	Viperin	NNP
cord-003130-p2h8p5bm	214	2	specifically	specifically	RB
cord-003130-p2h8p5bm	214	3	targets	target	VBZ
cord-003130-p2h8p5bm	214	4	the	the	DT
cord-003130-p2h8p5bm	214	5	plus	plus	NN
cord-003130-p2h8p5bm	214	6	-	-	HYPH
cord-003130-p2h8p5bm	214	7	sense	sense	NN
cord-003130-p2h8p5bm	214	8	RNA	RNA	NNP
cord-003130-p2h8p5bm	214	9	synthesis	synthesis	NN
cord-003130-p2h8p5bm	214	10	with	with	IN
cord-003130-p2h8p5bm	214	11	no	no	DT
cord-003130-p2h8p5bm	214	12	significant	significant	JJ
cord-003130-p2h8p5bm	214	13	effect	effect	NN
cord-003130-p2h8p5bm	214	14	on	on	IN
cord-003130-p2h8p5bm	214	15	the	the	DT
cord-003130-p2h8p5bm	214	16	negative	negative	JJ
cord-003130-p2h8p5bm	214	17	-	-	HYPH
cord-003130-p2h8p5bm	214	18	sense	sense	NN
cord-003130-p2h8p5bm	214	19	RNA	RNA	NNP
cord-003130-p2h8p5bm	214	20	of	of	IN
cord-003130-p2h8p5bm	214	21	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	214	22	during	during	IN
cord-003130-p2h8p5bm	214	23	genomic	genomic	JJ
cord-003130-p2h8p5bm	214	24	replication	replication	NN
cord-003130-p2h8p5bm	214	25	[	[	-LRB-
cord-003130-p2h8p5bm	214	26	149	149	CD
cord-003130-p2h8p5bm	214	27	]	]	-RRB-
cord-003130-p2h8p5bm	214	28	.	.	.
cord-003130-p2h8p5bm	215	1	Viperin	Viperin	NNP
cord-003130-p2h8p5bm	215	2	's	's	POS
cord-003130-p2h8p5bm	215	3	Fe	Fe	NNP
cord-003130-p2h8p5bm	215	4	/	/	SYM
cord-003130-p2h8p5bm	215	5	S	S	NNP
cord-003130-p2h8p5bm	215	6	maturation	maturation	NN
cord-003130-p2h8p5bm	215	7	is	be	VBZ
cord-003130-p2h8p5bm	215	8	dependent	dependent	JJ
cord-003130-p2h8p5bm	215	9	on	on	IN
cord-003130-p2h8p5bm	215	10	Ciao1	Ciao1	NNS
cord-003130-p2h8p5bm	215	11	[	[	-LRB-
cord-003130-p2h8p5bm	215	12	149	149	CD
cord-003130-p2h8p5bm	215	13	,	,	,
cord-003130-p2h8p5bm	215	14	167	167	CD
cord-003130-p2h8p5bm	215	15	]	]	-RRB-
cord-003130-p2h8p5bm	215	16	.	.	.
cord-003130-p2h8p5bm	216	1	The	the	DT
cord-003130-p2h8p5bm	216	2	Fe	Fe	NNP
cord-003130-p2h8p5bm	216	3	/	/	SYM
cord-003130-p2h8p5bm	216	4	S	S	NNP
cord-003130-p2h8p5bm	216	5	cluster	cluster	NN
cord-003130-p2h8p5bm	216	6	and	and	CC
cord-003130-p2h8p5bm	216	7	a	a	DT
cord-003130-p2h8p5bm	216	8	functional	functional	JJ
cord-003130-p2h8p5bm	216	9	SAM	SAM	NNP
cord-003130-p2h8p5bm	216	10	domain	domain	NN
cord-003130-p2h8p5bm	216	11	of	of	IN
cord-003130-p2h8p5bm	216	12	viperin	viperin	NNP
cord-003130-p2h8p5bm	216	13	is	be	VBZ
cord-003130-p2h8p5bm	216	14	essential	essential	JJ
cord-003130-p2h8p5bm	216	15	to	to	TO
cord-003130-p2h8p5bm	216	16	inhibit	inhibit	VB
cord-003130-p2h8p5bm	216	17	the	the	DT
cord-003130-p2h8p5bm	216	18	synthesis	synthesis	NN
cord-003130-p2h8p5bm	216	19	of	of	IN
cord-003130-p2h8p5bm	216	20	the	the	DT
cord-003130-p2h8p5bm	216	21	plus	plus	NN
cord-003130-p2h8p5bm	216	22	-	-	HYPH
cord-003130-p2h8p5bm	216	23	sense	sense	NN
cord-003130-p2h8p5bm	216	24	RNA	RNA	NNP
cord-003130-p2h8p5bm	216	25	of	of	IN
cord-003130-p2h8p5bm	216	26	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	216	27	[	[	-LRB-
cord-003130-p2h8p5bm	216	28	149	149	CD
cord-003130-p2h8p5bm	216	29	]	]	-RRB-
cord-003130-p2h8p5bm	216	30	.	.	.
cord-003130-p2h8p5bm	217	1	However	however	RB
cord-003130-p2h8p5bm	217	2	,	,	,
cord-003130-p2h8p5bm	217	3	the	the	DT
cord-003130-p2h8p5bm	217	4	target	target	NN
cord-003130-p2h8p5bm	217	5	for	for	IN
cord-003130-p2h8p5bm	217	6	the	the	DT
cord-003130-p2h8p5bm	217	7	radical	radical	JJ
cord-003130-p2h8p5bm	217	8	SAM	SAM	NNP
cord-003130-p2h8p5bm	217	9	activity	activity	NN
cord-003130-p2h8p5bm	217	10	important	important	JJ
cord-003130-p2h8p5bm	217	11	for	for	IN
cord-003130-p2h8p5bm	217	12	the	the	DT
cord-003130-p2h8p5bm	217	13	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	217	14	activity	activity	NN
cord-003130-p2h8p5bm	217	15	of	of	IN
cord-003130-p2h8p5bm	217	16	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	217	17	is	be	VBZ
cord-003130-p2h8p5bm	217	18	currently	currently	RB
cord-003130-p2h8p5bm	217	19	unknown	unknown	JJ
cord-003130-p2h8p5bm	217	20	.	.	.
cord-003130-p2h8p5bm	218	1	The	the	DT
cord-003130-p2h8p5bm	218	2	structure	structure	NN
cord-003130-p2h8p5bm	218	3	of	of	IN
cord-003130-p2h8p5bm	218	4	viperin	viperin	NNP
cord-003130-p2h8p5bm	218	5	was	be	VBD
cord-003130-p2h8p5bm	218	6	recently	recently	RB
cord-003130-p2h8p5bm	218	7	characterized	characterize	VBN
cord-003130-p2h8p5bm	218	8	[	[	-LRB-
cord-003130-p2h8p5bm	218	9	168	168	CD
cord-003130-p2h8p5bm	218	10	]	]	-RRB-
cord-003130-p2h8p5bm	218	11	,	,	,
cord-003130-p2h8p5bm	218	12	and	and	CC
cord-003130-p2h8p5bm	218	13	based	base	VBN
cord-003130-p2h8p5bm	218	14	on	on	IN
cord-003130-p2h8p5bm	218	15	similarities	similarity	NNS
cord-003130-p2h8p5bm	218	16	to	to	IN
cord-003130-p2h8p5bm	218	17	other	other	JJ
cord-003130-p2h8p5bm	218	18	radical	radical	JJ
cord-003130-p2h8p5bm	218	19	SAM	SAM	NNP
cord-003130-p2h8p5bm	218	20	enzymes	enzyme	NNS
cord-003130-p2h8p5bm	218	21	,	,	,
cord-003130-p2h8p5bm	218	22	several	several	JJ
cord-003130-p2h8p5bm	218	23	different	different	JJ
cord-003130-p2h8p5bm	218	24	hypothesis	hypothesis	NN
cord-003130-p2h8p5bm	218	25	have	have	VBP
cord-003130-p2h8p5bm	218	26	been	be	VBN
cord-003130-p2h8p5bm	218	27	put	put	VBN
cord-003130-p2h8p5bm	218	28	forward	forward	RB
cord-003130-p2h8p5bm	218	29	regarding	regard	VBG
cord-003130-p2h8p5bm	218	30	the	the	DT
cord-003130-p2h8p5bm	218	31	substrate	substrate	NN
cord-003130-p2h8p5bm	218	32	of	of	IN
cord-003130-p2h8p5bm	218	33	viperin	viperin	NNP
cord-003130-p2h8p5bm	218	34	and	and	CC
cord-003130-p2h8p5bm	218	35	its	-PRON-	PRP$
cord-003130-p2h8p5bm	218	36	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	218	37	activity	activity	NN
cord-003130-p2h8p5bm	218	38	[	[	-LRB-
cord-003130-p2h8p5bm	218	39	168	168	CD
cord-003130-p2h8p5bm	218	40	]	]	-RRB-
cord-003130-p2h8p5bm	218	41	[	[	-LRB-
cord-003130-p2h8p5bm	218	42	169	169	CD
cord-003130-p2h8p5bm	218	43	]	]	-RRB-
cord-003130-p2h8p5bm	218	44	[	[	-LRB-
cord-003130-p2h8p5bm	218	45	170	170	CD
cord-003130-p2h8p5bm	218	46	]	]	-RRB-
cord-003130-p2h8p5bm	218	47	.	.	.
cord-003130-p2h8p5bm	219	1	However	however	RB
cord-003130-p2h8p5bm	219	2	,	,	,
cord-003130-p2h8p5bm	219	3	none	none	NN
cord-003130-p2h8p5bm	219	4	of	of	IN
cord-003130-p2h8p5bm	219	5	these	these	DT
cord-003130-p2h8p5bm	219	6	have	have	VBP
cord-003130-p2h8p5bm	219	7	shown	show	VBN
cord-003130-p2h8p5bm	219	8	importance	importance	NN
cord-003130-p2h8p5bm	219	9	in	in	IN
cord-003130-p2h8p5bm	219	10	the	the	DT
cord-003130-p2h8p5bm	219	11	context	context	NN
cord-003130-p2h8p5bm	219	12	of	of	IN
cord-003130-p2h8p5bm	219	13	mammalian	mammalian	JJ
cord-003130-p2h8p5bm	219	14	viral	viral	JJ
cord-003130-p2h8p5bm	219	15	infection	infection	NN
cord-003130-p2h8p5bm	219	16	.	.	.
cord-003130-p2h8p5bm	220	1	Although	although	IN
cord-003130-p2h8p5bm	220	2	the	the	DT
cord-003130-p2h8p5bm	220	3	exact	exact	JJ
cord-003130-p2h8p5bm	220	4	mode	mode	NN
cord-003130-p2h8p5bm	220	5	of	of	IN
cord-003130-p2h8p5bm	220	6	action	action	NN
cord-003130-p2h8p5bm	220	7	against	against	IN
cord-003130-p2h8p5bm	220	8	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	220	9	is	be	VBZ
cord-003130-p2h8p5bm	220	10	not	not	RB
cord-003130-p2h8p5bm	220	11	well	well	RB
cord-003130-p2h8p5bm	220	12	understood	understand	VBN
cord-003130-p2h8p5bm	220	13	,	,	,
cord-003130-p2h8p5bm	220	14	recent	recent	JJ
cord-003130-p2h8p5bm	220	15	data	datum	NNS
cord-003130-p2h8p5bm	220	16	indicates	indicate	VBZ
cord-003130-p2h8p5bm	220	17	that	that	IN
cord-003130-p2h8p5bm	220	18	viperin	viperin	NNP
cord-003130-p2h8p5bm	220	19	interacts	interact	VBZ
cord-003130-p2h8p5bm	220	20	with	with	IN
cord-003130-p2h8p5bm	220	21	several	several	JJ
cord-003130-p2h8p5bm	220	22	viral	viral	JJ
cord-003130-p2h8p5bm	220	23	proteins	protein	NNS
cord-003130-p2h8p5bm	220	24	;	;	:
cord-003130-p2h8p5bm	220	25	both	both	DT
cord-003130-p2h8p5bm	220	26	structural	structural	JJ
cord-003130-p2h8p5bm	220	27	prM	prM	NNP
cord-003130-p2h8p5bm	220	28	and	and	CC
cord-003130-p2h8p5bm	220	29	E	e	NN
cord-003130-p2h8p5bm	220	30	and	and	CC
cord-003130-p2h8p5bm	220	31	non	non	JJ
cord-003130-p2h8p5bm	220	32	-	-	JJ
cord-003130-p2h8p5bm	220	33	structural	structural	JJ
cord-003130-p2h8p5bm	220	34	NS2A	NS2A	NNP
cord-003130-p2h8p5bm	220	35	,	,	,
cord-003130-p2h8p5bm	220	36	NS2B	NS2B	NNP
cord-003130-p2h8p5bm	220	37	,	,	,
cord-003130-p2h8p5bm	220	38	and	and	CC
cord-003130-p2h8p5bm	220	39	NS3	ns3	RB
cord-003130-p2h8p5bm	220	40	.	.	.
cord-003130-p2h8p5bm	221	1	These	these	DT
cord-003130-p2h8p5bm	221	2	interactions	interaction	NNS
cord-003130-p2h8p5bm	221	3	lead	lead	VBP
cord-003130-p2h8p5bm	221	4	to	to	IN
cord-003130-p2h8p5bm	221	5	a	a	DT
cord-003130-p2h8p5bm	221	6	viperin	viperin	NN
cord-003130-p2h8p5bm	221	7	-	-	:
cord-003130-p2h8p5bm	221	8	NS3	ns3	RB
cord-003130-p2h8p5bm	221	9	dependent	dependent	JJ
cord-003130-p2h8p5bm	221	10	degradation	degradation	NN
cord-003130-p2h8p5bm	221	11	of	of	IN
cord-003130-p2h8p5bm	221	12	viral	viral	JJ
cord-003130-p2h8p5bm	221	13	proteins	protein	NNS
cord-003130-p2h8p5bm	221	14	.	.	.
cord-003130-p2h8p5bm	222	1	The	the	DT
cord-003130-p2h8p5bm	222	2	degradation	degradation	NN
cord-003130-p2h8p5bm	222	3	of	of	IN
cord-003130-p2h8p5bm	222	4	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	222	5	NS3	ns3	RB
cord-003130-p2h8p5bm	222	6	was	be	VBD
cord-003130-p2h8p5bm	222	7	shown	show	VBN
cord-003130-p2h8p5bm	222	8	to	to	TO
cord-003130-p2h8p5bm	222	9	be	be	VB
cord-003130-p2h8p5bm	222	10	proteasome	proteasome	VBN
cord-003130-p2h8p5bm	222	11	dependent	dependent	JJ
cord-003130-p2h8p5bm	222	12	[	[	-LRB-
cord-003130-p2h8p5bm	222	13	150	150	CD
cord-003130-p2h8p5bm	222	14	]	]	-RRB-
cord-003130-p2h8p5bm	223	1	(	(	-LRB-
cord-003130-p2h8p5bm	223	2	Figure	figure	NN
cord-003130-p2h8p5bm	223	3	3	3	CD
cord-003130-p2h8p5bm	223	4	)	)	-RRB-
cord-003130-p2h8p5bm	223	5	.	.	.
cord-003130-p2h8p5bm	224	1	Interestingly	interestingly	RB
cord-003130-p2h8p5bm	224	2	,	,	,
cord-003130-p2h8p5bm	224	3	IFN	IFN	NNP
cord-003130-p2h8p5bm	224	4	treatment	treatment	NN
cord-003130-p2h8p5bm	224	5	induces	induce	VBZ
cord-003130-p2h8p5bm	224	6	an	an	DT
cord-003130-p2h8p5bm	224	7	increase	increase	NN
cord-003130-p2h8p5bm	224	8	of	of	IN
cord-003130-p2h8p5bm	224	9	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	224	10	capsid	capsid	NN
cord-003130-p2h8p5bm	224	11	particles	particle	NNS
cord-003130-p2h8p5bm	224	12	and	and	CC
cord-003130-p2h8p5bm	224	13	this	this	DT
cord-003130-p2h8p5bm	224	14	effect	effect	NN
cord-003130-p2h8p5bm	224	15	was	be	VBD
cord-003130-p2h8p5bm	224	16	found	find	VBN
cord-003130-p2h8p5bm	224	17	to	to	TO
cord-003130-p2h8p5bm	224	18	be	be	VB
cord-003130-p2h8p5bm	224	19	dependent	dependent	JJ
cord-003130-p2h8p5bm	224	20	on	on	IN
cord-003130-p2h8p5bm	224	21	viperin	viperin	NNP
cord-003130-p2h8p5bm	224	22	.	.	.
cord-003130-p2h8p5bm	225	1	Viperin	Viperin	NNP
cord-003130-p2h8p5bm	225	2	mediated	mediate	VBD
cord-003130-p2h8p5bm	225	3	this	this	DT
cord-003130-p2h8p5bm	225	4	effect	effect	NN
cord-003130-p2h8p5bm	225	5	by	by	IN
cord-003130-p2h8p5bm	225	6	interacting	interact	VBG
cord-003130-p2h8p5bm	225	7	,	,	,
cord-003130-p2h8p5bm	225	8	via	via	IN
cord-003130-p2h8p5bm	225	9	its	-PRON-	PRP$
cord-003130-p2h8p5bm	225	10	N	n	CD
cord-003130-p2h8p5bm	225	11	-	-	HYPH
cord-003130-p2h8p5bm	225	12	terminus	terminus	NN
cord-003130-p2h8p5bm	225	13	,	,	,
cord-003130-p2h8p5bm	225	14	with	with	IN
cord-003130-p2h8p5bm	225	15	the	the	DT
cord-003130-p2h8p5bm	225	16	cellular	cellular	JJ
cord-003130-p2h8p5bm	225	17	protein	protein	NN
cord-003130-p2h8p5bm	225	18	Golgi	Golgi	NNP
cord-003130-p2h8p5bm	225	19	Brefeldin	Brefeldin	NNP
cord-003130-p2h8p5bm	226	1	A	a	DT
cord-003130-p2h8p5bm	226	2	resistant	resistant	JJ
cord-003130-p2h8p5bm	226	3	guanine	guanine	NN
cord-003130-p2h8p5bm	226	4	nucleotide	nucleotide	JJ
cord-003130-p2h8p5bm	226	5	exchange	exchange	NN
cord-003130-p2h8p5bm	226	6	factor	factor	NN
cord-003130-p2h8p5bm	226	7	1	1	CD
cord-003130-p2h8p5bm	226	8	(	(	-LRB-
cord-003130-p2h8p5bm	226	9	GBF1	GBF1	NNP
cord-003130-p2h8p5bm	226	10	)	)	-RRB-
cord-003130-p2h8p5bm	226	11	[	[	-LRB-
cord-003130-p2h8p5bm	226	12	86	86	CD
cord-003130-p2h8p5bm	226	13	]	]	-RRB-
cord-003130-p2h8p5bm	226	14	.	.	.
cord-003130-p2h8p5bm	227	1	GBF1	GBF1	NNP
cord-003130-p2h8p5bm	227	2	is	be	VBZ
cord-003130-p2h8p5bm	227	3	a	a	DT
cord-003130-p2h8p5bm	227	4	key	key	JJ
cord-003130-p2h8p5bm	227	5	protein	protein	NN
cord-003130-p2h8p5bm	227	6	in	in	IN
cord-003130-p2h8p5bm	227	7	the	the	DT
cord-003130-p2h8p5bm	227	8	cellular	cellular	JJ
cord-003130-p2h8p5bm	227	9	secretory	secretory	JJ
cord-003130-p2h8p5bm	227	10	pathway	pathway	NN
cord-003130-p2h8p5bm	227	11	and	and	CC
cord-003130-p2h8p5bm	227	12	essential	essential	JJ
cord-003130-p2h8p5bm	227	13	in	in	IN
cord-003130-p2h8p5bm	227	14	the	the	DT
cord-003130-p2h8p5bm	227	15	life	life	NN
cord-003130-p2h8p5bm	227	16	cycle	cycle	NN
cord-003130-p2h8p5bm	227	17	of	of	IN
cord-003130-p2h8p5bm	227	18	many	many	JJ
cord-003130-p2h8p5bm	227	19	RNA	RNA	NNP
cord-003130-p2h8p5bm	227	20	viruses	virus	NNS
cord-003130-p2h8p5bm	227	21	,	,	,
cord-003130-p2h8p5bm	227	22	which	which	WDT
cord-003130-p2h8p5bm	227	23	utilize	utilize	VBP
cord-003130-p2h8p5bm	227	24	vesicular	vesicular	JJ
cord-003130-p2h8p5bm	227	25	trafficking	trafficking	NN
cord-003130-p2h8p5bm	227	26	in	in	IN
cord-003130-p2h8p5bm	227	27	their	-PRON-	PRP$
cord-003130-p2h8p5bm	227	28	replication	replication	NN
cord-003130-p2h8p5bm	227	29	cycle	cycle	NN
cord-003130-p2h8p5bm	227	30	and	and	CC
cord-003130-p2h8p5bm	227	31	assembly	assembly	NN
cord-003130-p2h8p5bm	227	32	process	process	NN
cord-003130-p2h8p5bm	227	33	[	[	-LRB-
cord-003130-p2h8p5bm	227	34	171	171	CD
cord-003130-p2h8p5bm	227	35	]	]	-RRB-
cord-003130-p2h8p5bm	227	36	[	[	-LRB-
cord-003130-p2h8p5bm	227	37	172	172	CD
cord-003130-p2h8p5bm	227	38	]	]	-RRB-
cord-003130-p2h8p5bm	227	39	[	[	-LRB-
cord-003130-p2h8p5bm	227	40	173	173	CD
cord-003130-p2h8p5bm	227	41	]	]	-RRB-
cord-003130-p2h8p5bm	227	42	[	[	-LRB-
cord-003130-p2h8p5bm	227	43	174	174	CD
cord-003130-p2h8p5bm	227	44	]	]	-RRB-
cord-003130-p2h8p5bm	227	45	(	(	-LRB-
cord-003130-p2h8p5bm	227	46	Figure	figure	NN
cord-003130-p2h8p5bm	227	47	3	3	CD
cord-003130-p2h8p5bm	227	48	)	)	-RRB-
cord-003130-p2h8p5bm	227	49	.	.	.
cord-003130-p2h8p5bm	228	1	Viperin	Viperin	NNP
cord-003130-p2h8p5bm	228	2	targets	target	VBZ
cord-003130-p2h8p5bm	228	3	the	the	DT
cord-003130-p2h8p5bm	228	4	NS3	ns3	RB
cord-003130-p2h8p5bm	228	5	protein	protein	NN
cord-003130-p2h8p5bm	228	6	for	for	IN
cord-003130-p2h8p5bm	228	7	proteasomal	proteasomal	JJ
cord-003130-p2h8p5bm	228	8	degradation	degradation	NN
cord-003130-p2h8p5bm	228	9	which	which	WDT
cord-003130-p2h8p5bm	228	10	inhibits	inhibit	VBZ
cord-003130-p2h8p5bm	228	11	the	the	DT
cord-003130-p2h8p5bm	228	12	synthesis	synthesis	NN
cord-003130-p2h8p5bm	228	13	of	of	IN
cord-003130-p2h8p5bm	228	14	+	+	SYM
cord-003130-p2h8p5bm	228	15	strand	strand	NN
cord-003130-p2h8p5bm	228	16	RNA	RNA	NNP
cord-003130-p2h8p5bm	228	17	.	.	.
cord-003130-p2h8p5bm	229	1	Furthermore	furthermore	RB
cord-003130-p2h8p5bm	229	2	,	,	,
cord-003130-p2h8p5bm	229	3	NS3	ns3	RB
cord-003130-p2h8p5bm	229	4	interacts	interact	VBZ
cord-003130-p2h8p5bm	229	5	with	with	IN
cord-003130-p2h8p5bm	229	6	E	E	NNP
cord-003130-p2h8p5bm	229	7	,	,	,
cord-003130-p2h8p5bm	229	8	NS2A	ns2a	UH
cord-003130-p2h8p5bm	229	9	,	,	,
cord-003130-p2h8p5bm	229	10	and	and	CC
cord-003130-p2h8p5bm	229	11	NS2B	NS2B	NNP
cord-003130-p2h8p5bm	229	12	and	and	CC
cord-003130-p2h8p5bm	229	13	these	these	DT
cord-003130-p2h8p5bm	229	14	proteins	protein	NNS
cord-003130-p2h8p5bm	229	15	are	be	VBP
cord-003130-p2h8p5bm	229	16	degraded	degrade	VBN
cord-003130-p2h8p5bm	229	17	by	by	IN
cord-003130-p2h8p5bm	229	18	viperin	viperin	NNP
cord-003130-p2h8p5bm	229	19	in	in	IN
cord-003130-p2h8p5bm	229	20	a	a	DT
cord-003130-p2h8p5bm	229	21	NS3-dependent	NS3-dependent	NNP
cord-003130-p2h8p5bm	229	22	manner	manner	NN
cord-003130-p2h8p5bm	229	23	.	.	.
cord-003130-p2h8p5bm	230	1	Viperin	Viperin	NNP
cord-003130-p2h8p5bm	230	2	also	also	RB
cord-003130-p2h8p5bm	230	3	interferes	interfere	VBZ
cord-003130-p2h8p5bm	230	4	with	with	IN
cord-003130-p2h8p5bm	230	5	particle	particle	NN
cord-003130-p2h8p5bm	230	6	assembly	assembly	NN
cord-003130-p2h8p5bm	230	7	by	by	IN
cord-003130-p2h8p5bm	230	8	inducing	induce	VBG
cord-003130-p2h8p5bm	230	9	secretion	secretion	NN
cord-003130-p2h8p5bm	230	10	of	of	IN
cord-003130-p2h8p5bm	230	11	C	c	NN
cord-003130-p2h8p5bm	230	12	particles	particle	NNS
cord-003130-p2h8p5bm	230	13	in	in	IN
cord-003130-p2h8p5bm	230	14	a	a	DT
cord-003130-p2h8p5bm	230	15	COPII	COPII	NNP
cord-003130-p2h8p5bm	230	16	-	-	HYPH
cord-003130-p2h8p5bm	230	17	dependent	dependent	JJ
cord-003130-p2h8p5bm	230	18	manner	manner	NN
cord-003130-p2h8p5bm	230	19	,	,	,
cord-003130-p2h8p5bm	230	20	independent	independent	JJ
cord-003130-p2h8p5bm	230	21	of	of	IN
cord-003130-p2h8p5bm	230	22	COPI	COPI	NNP
cord-003130-p2h8p5bm	230	23	.	.	.
cord-003130-p2h8p5bm	231	1	Viperin	Viperin	NNP
cord-003130-p2h8p5bm	231	2	mediates	mediate	VBZ
cord-003130-p2h8p5bm	231	3	this	this	DT
cord-003130-p2h8p5bm	231	4	effect	effect	NN
cord-003130-p2h8p5bm	231	5	by	by	IN
cord-003130-p2h8p5bm	231	6	interacting	interact	VBG
cord-003130-p2h8p5bm	231	7	and	and	CC
cord-003130-p2h8p5bm	231	8	sequestering	sequester	VBG
cord-003130-p2h8p5bm	231	9	GBF1	GBF1	NNP
cord-003130-p2h8p5bm	231	10	.	.	.
cord-003130-p2h8p5bm	232	1	Red	red	JJ
cord-003130-p2h8p5bm	232	2	arrow	arrow	NN
cord-003130-p2h8p5bm	232	3	=	=	SYM
cord-003130-p2h8p5bm	232	4	secretory	secretory	NN
cord-003130-p2h8p5bm	232	5	pathway	pathway	NN
cord-003130-p2h8p5bm	232	6	,	,	,
cord-003130-p2h8p5bm	232	7	blue	blue	JJ
cord-003130-p2h8p5bm	232	8	arrow	arrow	NN
cord-003130-p2h8p5bm	232	9	=	=	SYM
cord-003130-p2h8p5bm	232	10	"	"	''
cord-003130-p2h8p5bm	232	11	?	?	.
cord-003130-p2h8p5bm	233	1	"	"	``
cord-003130-p2h8p5bm	233	2	vesicular	vesicular	JJ
cord-003130-p2h8p5bm	233	3	transport	transport	NN
cord-003130-p2h8p5bm	233	4	via	via	IN
cord-003130-p2h8p5bm	233	5	unknown	unknown	JJ
cord-003130-p2h8p5bm	233	6	pathway	pathway	NN
cord-003130-p2h8p5bm	233	7	.	.	.
cord-003130-p2h8p5bm	234	1	Although	although	IN
cord-003130-p2h8p5bm	234	2	viperin	viperin	NNP
cord-003130-p2h8p5bm	234	3	has	have	VBZ
cord-003130-p2h8p5bm	234	4	been	be	VBN
cord-003130-p2h8p5bm	234	5	demonstrated	demonstrate	VBN
cord-003130-p2h8p5bm	234	6	to	to	TO
cord-003130-p2h8p5bm	234	7	be	be	VB
cord-003130-p2h8p5bm	234	8	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	234	9	active	active	JJ
cord-003130-p2h8p5bm	234	10	against	against	IN
cord-003130-p2h8p5bm	234	11	many	many	JJ
cord-003130-p2h8p5bm	234	12	different	different	JJ
cord-003130-p2h8p5bm	234	13	viruses	virus	NNS
cord-003130-p2h8p5bm	234	14	in	in	IN
cord-003130-p2h8p5bm	234	15	vitro	vitro	FW
cord-003130-p2h8p5bm	234	16	,	,	,
cord-003130-p2h8p5bm	234	17	few	few	JJ
cord-003130-p2h8p5bm	234	18	studies	study	NNS
cord-003130-p2h8p5bm	234	19	have	have	VBP
cord-003130-p2h8p5bm	234	20	investigated	investigate	VBN
cord-003130-p2h8p5bm	234	21	viperin	viperin	NNP
cord-003130-p2h8p5bm	234	22	's	's	POS
cord-003130-p2h8p5bm	234	23	role	role	NN
cord-003130-p2h8p5bm	234	24	in	in	IN
cord-003130-p2h8p5bm	234	25	vivo	vivo	NNP
cord-003130-p2h8p5bm	234	26	.	.	.
cord-003130-p2h8p5bm	235	1	In	in	IN
cord-003130-p2h8p5bm	235	2	TBFV	TBFV	NNP
cord-003130-p2h8p5bm	235	3	infection	infection	NN
cord-003130-p2h8p5bm	235	4	,	,	,
cord-003130-p2h8p5bm	235	5	viperin	viperin	NNP
cord-003130-p2h8p5bm	235	6	was	be	VBD
cord-003130-p2h8p5bm	235	7	shown	show	VBN
cord-003130-p2h8p5bm	235	8	to	to	TO
cord-003130-p2h8p5bm	235	9	control	control	VB
cord-003130-p2h8p5bm	235	10	LGTV	LGTV	NNP
cord-003130-p2h8p5bm	235	11	dissemination	dissemination	NN
cord-003130-p2h8p5bm	235	12	and	and	CC
cord-003130-p2h8p5bm	235	13	replication	replication	NN
cord-003130-p2h8p5bm	235	14	in	in	IN
cord-003130-p2h8p5bm	235	15	the	the	DT
cord-003130-p2h8p5bm	235	16	brain	brain	NN
cord-003130-p2h8p5bm	235	17	after	after	IN
cord-003130-p2h8p5bm	235	18	intraperitoneal	intraperitoneal	JJ
cord-003130-p2h8p5bm	235	19	administration	administration	NN
cord-003130-p2h8p5bm	235	20	,	,	,
cord-003130-p2h8p5bm	235	21	and	and	CC
cord-003130-p2h8p5bm	235	22	viperin	viperin	NNP
cord-003130-p2h8p5bm	235	23	promoted	promote	VBD
cord-003130-p2h8p5bm	235	24	survival	survival	NN
cord-003130-p2h8p5bm	235	25	after	after	IN
cord-003130-p2h8p5bm	235	26	intracranial	intracranial	JJ
cord-003130-p2h8p5bm	235	27	infection	infection	NN
cord-003130-p2h8p5bm	235	28	[	[	-LRB-
cord-003130-p2h8p5bm	235	29	141	141	CD
cord-003130-p2h8p5bm	235	30	]	]	-RRB-
cord-003130-p2h8p5bm	235	31	.	.	.
cord-003130-p2h8p5bm	236	1	Interestingly	interestingly	RB
cord-003130-p2h8p5bm	236	2	,	,	,
cord-003130-p2h8p5bm	236	3	viperin	viperin	NNP
cord-003130-p2h8p5bm	236	4	has	have	VBZ
cord-003130-p2h8p5bm	236	5	been	be	VBN
cord-003130-p2h8p5bm	236	6	shown	show	VBN
cord-003130-p2h8p5bm	236	7	to	to	TO
cord-003130-p2h8p5bm	236	8	be	be	VB
cord-003130-p2h8p5bm	236	9	expressed	express	VBN
cord-003130-p2h8p5bm	236	10	in	in	IN
cord-003130-p2h8p5bm	236	11	the	the	DT
cord-003130-p2h8p5bm	236	12	brain	brain	NN
cord-003130-p2h8p5bm	236	13	at	at	IN
cord-003130-p2h8p5bm	236	14	the	the	DT
cord-003130-p2h8p5bm	236	15	basal	basal	NN
cord-003130-p2h8p5bm	236	16	state	state	NN
cord-003130-p2h8p5bm	236	17	[	[	-LRB-
cord-003130-p2h8p5bm	236	18	128	128	CD
cord-003130-p2h8p5bm	236	19	]	]	-RRB-
cord-003130-p2h8p5bm	236	20	,	,	,
cord-003130-p2h8p5bm	236	21	with	with	IN
cord-003130-p2h8p5bm	236	22	high	high	JJ
cord-003130-p2h8p5bm	236	23	basal	basal	NN
cord-003130-p2h8p5bm	236	24	expression	expression	NN
cord-003130-p2h8p5bm	236	25	in	in	IN
cord-003130-p2h8p5bm	236	26	primary	primary	JJ
cord-003130-p2h8p5bm	236	27	astrocytes	astrocyte	NNS
cord-003130-p2h8p5bm	236	28	[	[	-LRB-
cord-003130-p2h8p5bm	236	29	100	100	CD
cord-003130-p2h8p5bm	236	30	,	,	,
cord-003130-p2h8p5bm	236	31	141	141	CD
cord-003130-p2h8p5bm	236	32	]	]	-RRB-
cord-003130-p2h8p5bm	236	33	.	.	.
cord-003130-p2h8p5bm	237	1	Viperin	Viperin	NNP
cord-003130-p2h8p5bm	237	2	's	's	POS
cord-003130-p2h8p5bm	237	3	role	role	NN
cord-003130-p2h8p5bm	237	4	within	within	IN
cord-003130-p2h8p5bm	237	5	the	the	DT
cord-003130-p2h8p5bm	237	6	brain	brain	NN
cord-003130-p2h8p5bm	237	7	during	during	IN
cord-003130-p2h8p5bm	237	8	neurotropic	neurotropic	NNP
cord-003130-p2h8p5bm	237	9	LGTV	LGTV	NNP
cord-003130-p2h8p5bm	237	10	infection	infection	NN
cord-003130-p2h8p5bm	237	11	was	be	VBD
cord-003130-p2h8p5bm	237	12	further	further	RB
cord-003130-p2h8p5bm	237	13	mapped	map	VBN
cord-003130-p2h8p5bm	237	14	to	to	IN
cord-003130-p2h8p5bm	237	15	certain	certain	JJ
cord-003130-p2h8p5bm	237	16	brain	brain	NN
cord-003130-p2h8p5bm	237	17	regions	region	NNS
cord-003130-p2h8p5bm	237	18	,	,	,
cord-003130-p2h8p5bm	237	19	as	as	IN
cord-003130-p2h8p5bm	237	20	viperin	viperin	NNP
cord-003130-p2h8p5bm	237	21	inhibited	inhibit	VBD
cord-003130-p2h8p5bm	237	22	viral	viral	JJ
cord-003130-p2h8p5bm	237	23	replication	replication	NN
cord-003130-p2h8p5bm	237	24	in	in	IN
cord-003130-p2h8p5bm	237	25	the	the	DT
cord-003130-p2h8p5bm	237	26	olfactory	olfactory	JJ
cord-003130-p2h8p5bm	237	27	bulb	bulb	NN
cord-003130-p2h8p5bm	237	28	and	and	CC
cord-003130-p2h8p5bm	237	29	cerebrum	cerebrum	NNP
cord-003130-p2h8p5bm	237	30	,	,	,
cord-003130-p2h8p5bm	237	31	but	but	CC
cord-003130-p2h8p5bm	237	32	not	not	RB
cord-003130-p2h8p5bm	237	33	in	in	IN
cord-003130-p2h8p5bm	237	34	the	the	DT
cord-003130-p2h8p5bm	237	35	cerebellum	cerebellum	NN
cord-003130-p2h8p5bm	237	36	or	or	CC
cord-003130-p2h8p5bm	237	37	brainstem	brainstem	NN
cord-003130-p2h8p5bm	237	38	.	.	.
cord-003130-p2h8p5bm	238	1	This	this	DT
cord-003130-p2h8p5bm	238	2	correlates	correlate	VBZ
cord-003130-p2h8p5bm	238	3	very	very	RB
cord-003130-p2h8p5bm	238	4	well	well	RB
cord-003130-p2h8p5bm	238	5	with	with	IN
cord-003130-p2h8p5bm	238	6	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	238	7	infection	infection	NN
cord-003130-p2h8p5bm	238	8	since	since	IN
cord-003130-p2h8p5bm	238	9	viperin	viperin	NNP
cord-003130-p2h8p5bm	238	10	strongly	strongly	RB
cord-003130-p2h8p5bm	238	11	inhibited	inhibit	VBD
cord-003130-p2h8p5bm	238	12	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	238	13	replication	replication	NN
cord-003130-p2h8p5bm	238	14	in	in	IN
cord-003130-p2h8p5bm	238	15	primary	primary	JJ
cord-003130-p2h8p5bm	238	16	neurons	neuron	NNS
cord-003130-p2h8p5bm	238	17	and	and	CC
cord-003130-p2h8p5bm	238	18	astrocytes	astrocyte	NNS
cord-003130-p2h8p5bm	238	19	from	from	IN
cord-003130-p2h8p5bm	238	20	the	the	DT
cord-003130-p2h8p5bm	238	21	cerebrum	cerebrum	NN
cord-003130-p2h8p5bm	238	22	,	,	,
cord-003130-p2h8p5bm	238	23	but	but	CC
cord-003130-p2h8p5bm	238	24	not	not	RB
cord-003130-p2h8p5bm	238	25	in	in	IN
cord-003130-p2h8p5bm	238	26	granular	granular	JJ
cord-003130-p2h8p5bm	238	27	cell	cell	NN
cord-003130-p2h8p5bm	238	28	neurons	neuron	NNS
cord-003130-p2h8p5bm	238	29	isolated	isolate	VBN
cord-003130-p2h8p5bm	238	30	from	from	IN
cord-003130-p2h8p5bm	238	31	the	the	DT
cord-003130-p2h8p5bm	238	32	cerebellum	cerebellum	NN
cord-003130-p2h8p5bm	238	33	.	.	.
cord-003130-p2h8p5bm	239	1	Interestingly	interestingly	RB
cord-003130-p2h8p5bm	239	2	,	,	,
cord-003130-p2h8p5bm	239	3	cortical	cortical	JJ
cord-003130-p2h8p5bm	239	4	neurons	neuron	NNS
cord-003130-p2h8p5bm	239	5	were	be	VBD
cord-003130-p2h8p5bm	239	6	completely	completely	RB
cord-003130-p2h8p5bm	239	7	dependent	dependent	JJ
cord-003130-p2h8p5bm	239	8	on	on	IN
cord-003130-p2h8p5bm	239	9	viperin	viperin	NN
cord-003130-p2h8p5bm	239	10	for	for	IN
cord-003130-p2h8p5bm	239	11	IFN	IFN	NNP
cord-003130-p2h8p5bm	239	12	-	-	HYPH
cord-003130-p2h8p5bm	239	13	mediated	mediate	VBN
cord-003130-p2h8p5bm	239	14	inhibition	inhibition	NN
cord-003130-p2h8p5bm	239	15	of	of	IN
cord-003130-p2h8p5bm	239	16	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	239	17	,	,	,
cord-003130-p2h8p5bm	239	18	whereas	whereas	IN
cord-003130-p2h8p5bm	239	19	in	in	IN
cord-003130-p2h8p5bm	239	20	astrocytes	astrocyte	NNS
cord-003130-p2h8p5bm	239	21	,	,	,
cord-003130-p2h8p5bm	239	22	in	in	IN
cord-003130-p2h8p5bm	239	23	which	which	WDT
cord-003130-p2h8p5bm	239	24	the	the	DT
cord-003130-p2h8p5bm	239	25	IFN	IFN	NNP
cord-003130-p2h8p5bm	239	26	-	-	HYPH
cord-003130-p2h8p5bm	239	27	mediated	mediate	VBN
cord-003130-p2h8p5bm	239	28	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	239	29	activities	activity	NNS
cord-003130-p2h8p5bm	239	30	are	be	VBP
cord-003130-p2h8p5bm	239	31	strongly	strongly	RB
cord-003130-p2h8p5bm	239	32	dependent	dependent	JJ
cord-003130-p2h8p5bm	239	33	on	on	IN
cord-003130-p2h8p5bm	239	34	viperin	viperin	NNP
cord-003130-p2h8p5bm	239	35	,	,	,
cord-003130-p2h8p5bm	239	36	other	other	JJ
cord-003130-p2h8p5bm	239	37	ISGs	isg	NNS
cord-003130-p2h8p5bm	239	38	could	could	MD
cord-003130-p2h8p5bm	239	39	partly	partly	RB
cord-003130-p2h8p5bm	239	40	compensate	compensate	VB
cord-003130-p2h8p5bm	239	41	for	for	IN
cord-003130-p2h8p5bm	239	42	loss	loss	NN
cord-003130-p2h8p5bm	239	43	of	of	IN
cord-003130-p2h8p5bm	239	44	viperin	viperin	NNP
cord-003130-p2h8p5bm	239	45	[	[	-LRB-
cord-003130-p2h8p5bm	239	46	141	141	CD
cord-003130-p2h8p5bm	239	47	]	]	-RRB-
cord-003130-p2h8p5bm	239	48	.	.	.
cord-003130-p2h8p5bm	240	1	Taken	take	VBN
cord-003130-p2h8p5bm	240	2	together	together	RB
cord-003130-p2h8p5bm	240	3	,	,	,
cord-003130-p2h8p5bm	240	4	viperin	viperin	NNP
cord-003130-p2h8p5bm	240	5	has	have	VBZ
cord-003130-p2h8p5bm	240	6	been	be	VBN
cord-003130-p2h8p5bm	240	7	shown	show	VBN
cord-003130-p2h8p5bm	240	8	to	to	TO
cord-003130-p2h8p5bm	240	9	be	be	VB
cord-003130-p2h8p5bm	240	10	an	an	DT
cord-003130-p2h8p5bm	240	11	ISG	ISG	NNP
cord-003130-p2h8p5bm	240	12	that	that	WDT
cord-003130-p2h8p5bm	240	13	strongly	strongly	RB
cord-003130-p2h8p5bm	240	14	inhibits	inhibit	VBZ
cord-003130-p2h8p5bm	240	15	tick	tick	NN
cord-003130-p2h8p5bm	240	16	-	-	HYPH
cord-003130-p2h8p5bm	240	17	borne	bear	VBN
cord-003130-p2h8p5bm	240	18	flaviviruses	flavivirus	NNS
cord-003130-p2h8p5bm	240	19	in	in	IN
cord-003130-p2h8p5bm	240	20	vivo	vivo	NN
cord-003130-p2h8p5bm	240	21	and	and	CC
cord-003130-p2h8p5bm	240	22	in	in	IN
cord-003130-p2h8p5bm	240	23	vitro	vitro	FW
cord-003130-p2h8p5bm	240	24	.	.	.
cord-003130-p2h8p5bm	241	1	This	this	DT
cord-003130-p2h8p5bm	241	2	strong	strong	JJ
cord-003130-p2h8p5bm	241	3	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	241	4	effect	effect	NN
cord-003130-p2h8p5bm	241	5	on	on	IN
cord-003130-p2h8p5bm	241	6	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	241	7	is	be	VBZ
cord-003130-p2h8p5bm	241	8	mediated	mediate	VBN
cord-003130-p2h8p5bm	241	9	by	by	IN
cord-003130-p2h8p5bm	241	10	targeting	target	VBG
cord-003130-p2h8p5bm	241	11	the	the	DT
cord-003130-p2h8p5bm	241	12	virus	virus	NN
cord-003130-p2h8p5bm	241	13	at	at	IN
cord-003130-p2h8p5bm	241	14	multiple	multiple	JJ
cord-003130-p2h8p5bm	241	15	steps	step	NNS
cord-003130-p2h8p5bm	241	16	of	of	IN
cord-003130-p2h8p5bm	241	17	the	the	DT
cord-003130-p2h8p5bm	241	18	life	life	NN
cord-003130-p2h8p5bm	241	19	cycle	cycle	NN
cord-003130-p2h8p5bm	241	20	.	.	.
cord-003130-p2h8p5bm	242	1	Interestingly	interestingly	RB
cord-003130-p2h8p5bm	242	2	,	,	,
cord-003130-p2h8p5bm	242	3	viperin	viperin	NNP
cord-003130-p2h8p5bm	242	4	targeting	target	VBG
cord-003130-p2h8p5bm	242	5	the	the	DT
cord-003130-p2h8p5bm	242	6	synthesis	synthesis	NN
cord-003130-p2h8p5bm	242	7	of	of	IN
cord-003130-p2h8p5bm	242	8	plus	plus	NN
cord-003130-p2h8p5bm	242	9	-	-	HYPH
cord-003130-p2h8p5bm	242	10	sense	sense	NN
cord-003130-p2h8p5bm	242	11	RNA	RNA	NNP
cord-003130-p2h8p5bm	242	12	is	be	VBZ
cord-003130-p2h8p5bm	242	13	dependent	dependent	JJ
cord-003130-p2h8p5bm	242	14	on	on	IN
cord-003130-p2h8p5bm	242	15	the	the	DT
cord-003130-p2h8p5bm	242	16	SAM	SAM	NNP
cord-003130-p2h8p5bm	242	17	domain	domain	NN
cord-003130-p2h8p5bm	242	18	or	or	CC
cord-003130-p2h8p5bm	242	19	the	the	DT
cord-003130-p2h8p5bm	242	20	C	c	NN
cord-003130-p2h8p5bm	242	21	-	-	HYPH
cord-003130-p2h8p5bm	242	22	terminal	terminal	NN
cord-003130-p2h8p5bm	242	23	domain	domain	NN
cord-003130-p2h8p5bm	242	24	,	,	,
cord-003130-p2h8p5bm	242	25	while	while	IN
cord-003130-p2h8p5bm	242	26	the	the	DT
cord-003130-p2h8p5bm	242	27	N	n	CD
cord-003130-p2h8p5bm	242	28	-	-	HYPH
cord-003130-p2h8p5bm	242	29	terminal	terminal	NN
cord-003130-p2h8p5bm	242	30	domain	domain	NN
cord-003130-p2h8p5bm	242	31	of	of	IN
cord-003130-p2h8p5bm	242	32	viperin	viperin	NNP
cord-003130-p2h8p5bm	242	33	is	be	VBZ
cord-003130-p2h8p5bm	242	34	responsible	responsible	JJ
cord-003130-p2h8p5bm	242	35	for	for	IN
cord-003130-p2h8p5bm	242	36	interfering	interfere	VBG
cord-003130-p2h8p5bm	242	37	with	with	IN
cord-003130-p2h8p5bm	242	38	virus	virus	NN
cord-003130-p2h8p5bm	242	39	assembly	assembly	NN
cord-003130-p2h8p5bm	242	40	and	and	CC
cord-003130-p2h8p5bm	242	41	release	release	NN
cord-003130-p2h8p5bm	242	42	.	.	.
cord-003130-p2h8p5bm	243	1	In	in	IN
cord-003130-p2h8p5bm	243	2	order	order	NN
cord-003130-p2h8p5bm	243	3	to	to	TO
cord-003130-p2h8p5bm	243	4	establish	establish	VB
cord-003130-p2h8p5bm	243	5	an	an	DT
cord-003130-p2h8p5bm	243	6	infection	infection	NN
cord-003130-p2h8p5bm	243	7	,	,	,
cord-003130-p2h8p5bm	243	8	a	a	DT
cord-003130-p2h8p5bm	243	9	pathogen	pathogen	NN
cord-003130-p2h8p5bm	243	10	needs	need	VBZ
cord-003130-p2h8p5bm	243	11	to	to	TO
cord-003130-p2h8p5bm	243	12	overcome	overcome	VB
cord-003130-p2h8p5bm	243	13	or	or	CC
cord-003130-p2h8p5bm	243	14	evade	evade	VB
cord-003130-p2h8p5bm	243	15	the	the	DT
cord-003130-p2h8p5bm	243	16	innate	innate	JJ
cord-003130-p2h8p5bm	243	17	immune	immune	JJ
cord-003130-p2h8p5bm	243	18	response	response	NN
cord-003130-p2h8p5bm	243	19	.	.	.
cord-003130-p2h8p5bm	244	1	To	to	TO
cord-003130-p2h8p5bm	244	2	breach	breach	VB
cord-003130-p2h8p5bm	244	3	the	the	DT
cord-003130-p2h8p5bm	244	4	very	very	RB
cord-003130-p2h8p5bm	244	5	first	first	JJ
cord-003130-p2h8p5bm	244	6	line	line	NN
cord-003130-p2h8p5bm	244	7	of	of	IN
cord-003130-p2h8p5bm	244	8	defense	defense	NN
cord-003130-p2h8p5bm	244	9	,	,	,
cord-003130-p2h8p5bm	244	10	the	the	DT
cord-003130-p2h8p5bm	244	11	skin	skin	NN
cord-003130-p2h8p5bm	244	12	-	-	HYPH
cord-003130-p2h8p5bm	244	13	TBFVs	tbfvs	NN
cord-003130-p2h8p5bm	244	14	use	use	VBP
cord-003130-p2h8p5bm	244	15	the	the	DT
cord-003130-p2h8p5bm	244	16	tick	tick	NN
cord-003130-p2h8p5bm	244	17	to	to	TO
cord-003130-p2h8p5bm	244	18	deliver	deliver	VB
cord-003130-p2h8p5bm	244	19	the	the	DT
cord-003130-p2h8p5bm	244	20	virus	virus	NN
cord-003130-p2h8p5bm	244	21	through	through	IN
cord-003130-p2h8p5bm	244	22	the	the	DT
cord-003130-p2h8p5bm	244	23	skin	skin	NN
cord-003130-p2h8p5bm	244	24	via	via	IN
cord-003130-p2h8p5bm	244	25	tick	tick	NN
cord-003130-p2h8p5bm	244	26	saliva	saliva	NN
cord-003130-p2h8p5bm	244	27	.	.	.
cord-003130-p2h8p5bm	245	1	Furthermore	furthermore	RB
cord-003130-p2h8p5bm	245	2	,	,	,
cord-003130-p2h8p5bm	245	3	tick	tick	VB
cord-003130-p2h8p5bm	245	4	saliva	saliva	NN
cord-003130-p2h8p5bm	245	5	contains	contain	VBZ
cord-003130-p2h8p5bm	245	6	immunomodulatory	immunomodulatory	JJ
cord-003130-p2h8p5bm	245	7	compounds	compound	NNS
cord-003130-p2h8p5bm	245	8	that	that	WDT
cord-003130-p2h8p5bm	245	9	enhance	enhance	VBP
cord-003130-p2h8p5bm	245	10	viral	viral	JJ
cord-003130-p2h8p5bm	245	11	transmission	transmission	NN
cord-003130-p2h8p5bm	245	12	and	and	CC
cord-003130-p2h8p5bm	245	13	dissemination	dissemination	NN
cord-003130-p2h8p5bm	245	14	[	[	-LRB-
cord-003130-p2h8p5bm	245	15	175	175	CD
cord-003130-p2h8p5bm	245	16	,	,	,
cord-003130-p2h8p5bm	245	17	176	176	CD
cord-003130-p2h8p5bm	245	18	]	]	-RRB-
cord-003130-p2h8p5bm	245	19	.	.	.
cord-003130-p2h8p5bm	246	1	Although	although	IN
cord-003130-p2h8p5bm	246	2	there	there	EX
cord-003130-p2h8p5bm	246	3	are	be	VBP
cord-003130-p2h8p5bm	246	4	several	several	JJ
cord-003130-p2h8p5bm	246	5	mechanisms	mechanism	NNS
cord-003130-p2h8p5bm	246	6	in	in	IN
cord-003130-p2h8p5bm	246	7	which	which	WDT
cord-003130-p2h8p5bm	246	8	mosquito	mosquito	NN
cord-003130-p2h8p5bm	246	9	-	-	HYPH
cord-003130-p2h8p5bm	246	10	borne	bear	VBN
cord-003130-p2h8p5bm	246	11	flaviviruses	flavivirus	NNS
cord-003130-p2h8p5bm	246	12	actively	actively	RB
cord-003130-p2h8p5bm	246	13	suppress	suppress	VBP
cord-003130-p2h8p5bm	246	14	the	the	DT
cord-003130-p2h8p5bm	246	15	induction	induction	NN
cord-003130-p2h8p5bm	246	16	of	of	IN
cord-003130-p2h8p5bm	246	17	type	type	NN
cord-003130-p2h8p5bm	246	18	I	-PRON-	PRP
cord-003130-p2h8p5bm	246	19	IFN	IFN	NNP
cord-003130-p2h8p5bm	246	20	,	,	,
cord-003130-p2h8p5bm	246	21	no	no	DT
cord-003130-p2h8p5bm	246	22	such	such	JJ
cord-003130-p2h8p5bm	246	23	mechanism	mechanism	NN
cord-003130-p2h8p5bm	246	24	has	have	VBZ
cord-003130-p2h8p5bm	246	25	been	be	VBN
cord-003130-p2h8p5bm	246	26	identified	identify	VBN
cord-003130-p2h8p5bm	246	27	in	in	IN
cord-003130-p2h8p5bm	246	28	tick	tick	NN
cord-003130-p2h8p5bm	246	29	-	-	HYPH
cord-003130-p2h8p5bm	246	30	borne	bear	VBN
cord-003130-p2h8p5bm	246	31	flaviviruses	flavivirus	NNS
cord-003130-p2h8p5bm	246	32	so	so	RB
cord-003130-p2h8p5bm	246	33	far	far	RB
cord-003130-p2h8p5bm	246	34	[	[	-LRB-
cord-003130-p2h8p5bm	246	35	177	177	CD
cord-003130-p2h8p5bm	246	36	]	]	-RRB-
cord-003130-p2h8p5bm	246	37	.	.	.
cord-003130-p2h8p5bm	247	1	Instead	instead	RB
cord-003130-p2h8p5bm	247	2	,	,	,
cord-003130-p2h8p5bm	247	3	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	247	4	,	,	,
cord-003130-p2h8p5bm	247	5	like	like	IN
cord-003130-p2h8p5bm	247	6	other	other	JJ
cord-003130-p2h8p5bm	247	7	flaviviruses	flavivirus	NNS
cord-003130-p2h8p5bm	247	8	,	,	,
cord-003130-p2h8p5bm	247	9	utilizes	utilize	VBZ
cord-003130-p2h8p5bm	247	10	a	a	DT
cord-003130-p2h8p5bm	247	11	passive	passive	JJ
cord-003130-p2h8p5bm	247	12	evasion	evasion	NN
cord-003130-p2h8p5bm	247	13	mechanism	mechanism	NN
cord-003130-p2h8p5bm	247	14	in	in	IN
cord-003130-p2h8p5bm	247	15	which	which	WDT
cord-003130-p2h8p5bm	247	16	the	the	DT
cord-003130-p2h8p5bm	247	17	virus	virus	NN
cord-003130-p2h8p5bm	247	18	hides	hide	VBZ
cord-003130-p2h8p5bm	247	19	its	-PRON-	PRP$
cord-003130-p2h8p5bm	247	20	dsRNA	dsrna	NN
cord-003130-p2h8p5bm	247	21	intermediates	intermediate	NNS
cord-003130-p2h8p5bm	247	22	in	in	IN
cord-003130-p2h8p5bm	247	23	vesicular	vesicular	JJ
cord-003130-p2h8p5bm	247	24	structures	structure	NNS
cord-003130-p2h8p5bm	247	25	inside	inside	IN
cord-003130-p2h8p5bm	247	26	the	the	DT
cord-003130-p2h8p5bm	247	27	ER	ER	NNP
cord-003130-p2h8p5bm	247	28	membranes	membrane	NNS
cord-003130-p2h8p5bm	247	29	,	,	,
cord-003130-p2h8p5bm	247	30	and	and	CC
cord-003130-p2h8p5bm	247	31	thus	thus	RB
cord-003130-p2h8p5bm	247	32	delaying	delay	VBG
cord-003130-p2h8p5bm	247	33	the	the	DT
cord-003130-p2h8p5bm	247	34	recognition	recognition	NN
cord-003130-p2h8p5bm	247	35	by	by	IN
cord-003130-p2h8p5bm	247	36	the	the	DT
cord-003130-p2h8p5bm	247	37	cytosolic	cytosolic	JJ
cord-003130-p2h8p5bm	247	38	RIG	rig	NN
cord-003130-p2h8p5bm	247	39	-	-	:
cord-003130-p2h8p5bm	247	40	I	-PRON-	PRP
cord-003130-p2h8p5bm	247	41	like	like	VBP
cord-003130-p2h8p5bm	247	42	receptors	receptor	NNS
cord-003130-p2h8p5bm	247	43	and	and	CC
cord-003130-p2h8p5bm	247	44	subsequent	subsequent	JJ
cord-003130-p2h8p5bm	247	45	IRF3	IRF3	NNP
cord-003130-p2h8p5bm	247	46	phosphorylation	phosphorylation	NN
cord-003130-p2h8p5bm	247	47	and	and	CC
cord-003130-p2h8p5bm	247	48	IFN	IFN	NNP
cord-003130-p2h8p5bm	247	49	induction	induction	NN
cord-003130-p2h8p5bm	247	50	(	(	-LRB-
cord-003130-p2h8p5bm	247	51	Figure	figure	NN
cord-003130-p2h8p5bm	247	52	4A	4a	CD
cord-003130-p2h8p5bm	247	53	)	)	-RRB-
cord-003130-p2h8p5bm	247	54	[	[	-LRB-
cord-003130-p2h8p5bm	247	55	80	80	CD
cord-003130-p2h8p5bm	247	56	,	,	,
cord-003130-p2h8p5bm	247	57	81	81	CD
cord-003130-p2h8p5bm	247	58	,	,	,
cord-003130-p2h8p5bm	247	59	83	83	CD
cord-003130-p2h8p5bm	247	60	]	]	-RRB-
cord-003130-p2h8p5bm	247	61	.	.	.
cord-003130-p2h8p5bm	248	1	The	the	DT
cord-003130-p2h8p5bm	248	2	most	most	RBS
cord-003130-p2h8p5bm	248	3	conserved	conserved	JJ
cord-003130-p2h8p5bm	248	4	inhibition	inhibition	NN
cord-003130-p2h8p5bm	248	5	of	of	IN
cord-003130-p2h8p5bm	248	6	the	the	DT
cord-003130-p2h8p5bm	248	7	type	type	NN
cord-003130-p2h8p5bm	249	1	I	-PRON-	PRP
cord-003130-p2h8p5bm	249	2	IFN	IFN	NNP
cord-003130-p2h8p5bm	249	3	system	system	NN
cord-003130-p2h8p5bm	249	4	within	within	IN
cord-003130-p2h8p5bm	249	5	the	the	DT
cord-003130-p2h8p5bm	249	6	Flaviviridae	Flaviviridae	NNP
cord-003130-p2h8p5bm	249	7	family	family	NN
cord-003130-p2h8p5bm	249	8	is	be	VBZ
cord-003130-p2h8p5bm	249	9	the	the	DT
cord-003130-p2h8p5bm	249	10	antagonism	antagonism	NN
cord-003130-p2h8p5bm	249	11	of	of	IN
cord-003130-p2h8p5bm	249	12	IFNAR	IFNAR	NNP
cord-003130-p2h8p5bm	249	13	signaling	signal	VBG
cord-003130-p2h8p5bm	249	14	carried	carry	VBN
cord-003130-p2h8p5bm	249	15	out	out	RP
cord-003130-p2h8p5bm	249	16	by	by	IN
cord-003130-p2h8p5bm	249	17	NS5	NS5	NNP
cord-003130-p2h8p5bm	249	18	;	;	:
cord-003130-p2h8p5bm	249	19	this	this	DT
cord-003130-p2h8p5bm	249	20	mechanism	mechanism	NN
cord-003130-p2h8p5bm	249	21	is	be	VBZ
cord-003130-p2h8p5bm	249	22	conserved	conserve	VBN
cord-003130-p2h8p5bm	249	23	between	between	IN
cord-003130-p2h8p5bm	249	24	several	several	JJ
cord-003130-p2h8p5bm	249	25	mosquito	mosquito	NN
cord-003130-p2h8p5bm	249	26	and	and	CC
cord-003130-p2h8p5bm	249	27	tick	tick	NN
cord-003130-p2h8p5bm	249	28	-	-	HYPH
cord-003130-p2h8p5bm	249	29	borne	bear	VBN
cord-003130-p2h8p5bm	249	30	flaviviruses	flavivirus	NNS
cord-003130-p2h8p5bm	249	31	[	[	-LRB-
cord-003130-p2h8p5bm	249	32	148	148	CD
cord-003130-p2h8p5bm	249	33	,	,	,
cord-003130-p2h8p5bm	249	34	[	[	-LRB-
cord-003130-p2h8p5bm	249	35	177	177	CD
cord-003130-p2h8p5bm	249	36	]	]	-RRB-
cord-003130-p2h8p5bm	249	37	[	[	-LRB-
cord-003130-p2h8p5bm	249	38	178	178	CD
cord-003130-p2h8p5bm	249	39	]	]	-RRB-
cord-003130-p2h8p5bm	249	40	[	[	-LRB-
cord-003130-p2h8p5bm	249	41	179	179	CD
cord-003130-p2h8p5bm	249	42	]	]	-RRB-
cord-003130-p2h8p5bm	249	43	[	[	-LRB-
cord-003130-p2h8p5bm	249	44	180	180	CD
cord-003130-p2h8p5bm	249	45	]	]	-RRB-
cord-003130-p2h8p5bm	249	46	[	[	-LRB-
cord-003130-p2h8p5bm	249	47	181	181	CD
cord-003130-p2h8p5bm	249	48	]	]	-RRB-
cord-003130-p2h8p5bm	249	49	.	.	.
cord-003130-p2h8p5bm	250	1	In	in	IN
cord-003130-p2h8p5bm	250	2	LGTV	LGTV	NNP
cord-003130-p2h8p5bm	250	3	infection	infection	NN
cord-003130-p2h8p5bm	250	4	,	,	,
cord-003130-p2h8p5bm	250	5	NS5	NS5	NNP
cord-003130-p2h8p5bm	250	6	was	be	VBD
cord-003130-p2h8p5bm	250	7	shown	show	VBN
cord-003130-p2h8p5bm	250	8	to	to	TO
cord-003130-p2h8p5bm	250	9	inhibit	inhibit	VB
cord-003130-p2h8p5bm	250	10	the	the	DT
cord-003130-p2h8p5bm	250	11	JAK	JAK	NNP
cord-003130-p2h8p5bm	250	12	-	-	HYPH
cord-003130-p2h8p5bm	250	13	STAT	stat	NN
cord-003130-p2h8p5bm	250	14	pathway	pathway	NN
cord-003130-p2h8p5bm	250	15	and	and	CC
cord-003130-p2h8p5bm	250	16	NS5	NS5	NNP
cord-003130-p2h8p5bm	250	17	was	be	VBD
cord-003130-p2h8p5bm	250	18	shown	show	VBN
cord-003130-p2h8p5bm	250	19	to	to	TO
cord-003130-p2h8p5bm	250	20	interact	interact	VB
cord-003130-p2h8p5bm	250	21	with	with	IN
cord-003130-p2h8p5bm	250	22	the	the	DT
cord-003130-p2h8p5bm	250	23	IFNAR	IFNAR	NNP
cord-003130-p2h8p5bm	250	24	receptor	receptor	NN
cord-003130-p2h8p5bm	250	25	[	[	-LRB-
cord-003130-p2h8p5bm	250	26	148	148	CD
cord-003130-p2h8p5bm	250	27	]	]	-RRB-
cord-003130-p2h8p5bm	250	28	.	.	.
cord-003130-p2h8p5bm	251	1	Similarly	similarly	RB
cord-003130-p2h8p5bm	251	2	,	,	,
cord-003130-p2h8p5bm	251	3	it	-PRON-	PRP
cord-003130-p2h8p5bm	251	4	was	be	VBD
cord-003130-p2h8p5bm	251	5	shown	show	VBN
cord-003130-p2h8p5bm	251	6	that	that	IN
cord-003130-p2h8p5bm	251	7	NS5	ns5	JJ
cord-003130-p2h8p5bm	251	8	of	of	IN
cord-003130-p2h8p5bm	251	9	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	251	10	interacts	interact	VBZ
cord-003130-p2h8p5bm	251	11	with	with	IN
cord-003130-p2h8p5bm	251	12	scribble	scribble	NN
cord-003130-p2h8p5bm	251	13	(	(	-LRB-
cord-003130-p2h8p5bm	251	14	hScrib	hScrib	NNP
cord-003130-p2h8p5bm	251	15	)	)	-RRB-
cord-003130-p2h8p5bm	251	16	which	which	WDT
cord-003130-p2h8p5bm	251	17	mediates	mediate	VBZ
cord-003130-p2h8p5bm	251	18	NS5	ns5	JJ
cord-003130-p2h8p5bm	251	19	localization	localization	NN
cord-003130-p2h8p5bm	251	20	to	to	IN
cord-003130-p2h8p5bm	251	21	the	the	DT
cord-003130-p2h8p5bm	251	22	plasma	plasma	NN
cord-003130-p2h8p5bm	251	23	membrane	membrane	NN
cord-003130-p2h8p5bm	251	24	and	and	CC
cord-003130-p2h8p5bm	251	25	this	this	DT
cord-003130-p2h8p5bm	251	26	interaction	interaction	NN
cord-003130-p2h8p5bm	251	27	enables	enable	VBZ
cord-003130-p2h8p5bm	251	28	NS5	ns5	JJ
cord-003130-p2h8p5bm	251	29	to	to	TO
cord-003130-p2h8p5bm	251	30	inhibit	inhibit	VB
cord-003130-p2h8p5bm	251	31	type	type	NN
cord-003130-p2h8p5bm	251	32	I	-PRON-	PRP
cord-003130-p2h8p5bm	251	33	and	and	CC
cord-003130-p2h8p5bm	251	34	type	type	NN
cord-003130-p2h8p5bm	251	35	II	II	NNP
cord-003130-p2h8p5bm	251	36	IFN	IFN	NNP
cord-003130-p2h8p5bm	251	37	mediated	mediate	VBD
cord-003130-p2h8p5bm	251	38	JAK	JAK	NNP
cord-003130-p2h8p5bm	251	39	-	-	HYPH
cord-003130-p2h8p5bm	251	40	STAT	STAT	NNP
cord-003130-p2h8p5bm	251	41	signaling	signal	VBG
cord-003130-p2h8p5bm	251	42	[	[	-LRB-
cord-003130-p2h8p5bm	251	43	178	178	CD
cord-003130-p2h8p5bm	251	44	]	]	-RRB-
cord-003130-p2h8p5bm	251	45	.	.	.
cord-003130-p2h8p5bm	252	1	Knockdown	knockdown	NN
cord-003130-p2h8p5bm	252	2	of	of	IN
cord-003130-p2h8p5bm	252	3	hScrib	hScrib	NNP
cord-003130-p2h8p5bm	252	4	altered	alter	VBD
cord-003130-p2h8p5bm	252	5	NS5	ns5	JJ
cord-003130-p2h8p5bm	252	6	cellular	cellular	JJ
cord-003130-p2h8p5bm	252	7	localization	localization	NN
cord-003130-p2h8p5bm	252	8	and	and	CC
cord-003130-p2h8p5bm	252	9	reversed	reverse	VBD
cord-003130-p2h8p5bm	252	10	the	the	DT
cord-003130-p2h8p5bm	252	11	inhibition	inhibition	NN
cord-003130-p2h8p5bm	252	12	of	of	IN
cord-003130-p2h8p5bm	252	13	the	the	DT
cord-003130-p2h8p5bm	252	14	JAK	JAK	NNP
cord-003130-p2h8p5bm	252	15	-	-	HYPH
cord-003130-p2h8p5bm	252	16	STAT	STAT	NNP
cord-003130-p2h8p5bm	252	17	signaling	signal	VBG
cord-003130-p2h8p5bm	252	18	[	[	-LRB-
cord-003130-p2h8p5bm	252	19	178	178	CD
cord-003130-p2h8p5bm	252	20	]	]	-RRB-
cord-003130-p2h8p5bm	252	21	.	.	.
cord-003130-p2h8p5bm	253	1	Further	further	JJ
cord-003130-p2h8p5bm	253	2	studies	study	NNS
cord-003130-p2h8p5bm	253	3	revealed	reveal	VBD
cord-003130-p2h8p5bm	253	4	that	that	IN
cord-003130-p2h8p5bm	253	5	NS5	NS5	NNP
cord-003130-p2h8p5bm	253	6	of	of	IN
cord-003130-p2h8p5bm	253	7	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	253	8	inhibited	inhibit	VBD
cord-003130-p2h8p5bm	253	9	the	the	DT
cord-003130-p2h8p5bm	253	10	cell	cell	NN
cord-003130-p2h8p5bm	253	11	surface	surface	NN
cord-003130-p2h8p5bm	253	12	expression	expression	NN
cord-003130-p2h8p5bm	253	13	of	of	IN
cord-003130-p2h8p5bm	253	14	IFNAR1	ifnar1	NN
cord-003130-p2h8p5bm	253	15	by	by	IN
cord-003130-p2h8p5bm	253	16	binding	bind	VBG
cord-003130-p2h8p5bm	253	17	to	to	IN
cord-003130-p2h8p5bm	253	18	prolidase	prolidase	NNP
cord-003130-p2h8p5bm	253	19	(	(	-LRB-
cord-003130-p2h8p5bm	253	20	PEPD	PEPD	NNP
cord-003130-p2h8p5bm	253	21	)	)	-RRB-
cord-003130-p2h8p5bm	253	22	[	[	-LRB-
cord-003130-p2h8p5bm	253	23	182	182	CD
cord-003130-p2h8p5bm	253	24	]	]	-RRB-
cord-003130-p2h8p5bm	253	25	.	.	.
cord-003130-p2h8p5bm	254	1	PEPD	PEPD	NNP
cord-003130-p2h8p5bm	254	2	is	be	VBZ
cord-003130-p2h8p5bm	254	3	a	a	DT
cord-003130-p2h8p5bm	254	4	peptidase	peptidase	NN
cord-003130-p2h8p5bm	254	5	that	that	WDT
cord-003130-p2h8p5bm	254	6	is	be	VBZ
cord-003130-p2h8p5bm	254	7	needed	need	VBN
cord-003130-p2h8p5bm	254	8	for	for	IN
cord-003130-p2h8p5bm	254	9	IFNAR1	ifnar1	NN
cord-003130-p2h8p5bm	254	10	maturation	maturation	NN
cord-003130-p2h8p5bm	254	11	and	and	CC
cord-003130-p2h8p5bm	254	12	subsequent	subsequent	JJ
cord-003130-p2h8p5bm	254	13	cell	cell	NN
cord-003130-p2h8p5bm	254	14	surface	surface	NN
cord-003130-p2h8p5bm	254	15	expression	expression	NN
cord-003130-p2h8p5bm	254	16	.	.	.
cord-003130-p2h8p5bm	255	1	NS5	ns5	JJ
cord-003130-p2h8p5bm	255	2	binding	binding	NN
cord-003130-p2h8p5bm	255	3	of	of	IN
cord-003130-p2h8p5bm	255	4	PEPD	PEPD	NNP
cord-003130-p2h8p5bm	255	5	prevented	prevent	VBD
cord-003130-p2h8p5bm	255	6	maturation	maturation	NN
cord-003130-p2h8p5bm	255	7	of	of	IN
cord-003130-p2h8p5bm	255	8	complex	complex	JJ
cord-003130-p2h8p5bm	255	9	N	n	CD
cord-003130-p2h8p5bm	255	10	-	-	HYPH
cord-003130-p2h8p5bm	255	11	linked	link	VBN
cord-003130-p2h8p5bm	255	12	oligosaccharides	oligosaccharide	NNS
cord-003130-p2h8p5bm	255	13	on	on	IN
cord-003130-p2h8p5bm	255	14	IFNAR1	ifnar1	NN
cord-003130-p2h8p5bm	255	15	,	,	,
cord-003130-p2h8p5bm	255	16	which	which	WDT
cord-003130-p2h8p5bm	255	17	in	in	IN
cord-003130-p2h8p5bm	255	18	turn	turn	NN
cord-003130-p2h8p5bm	255	19	disrupted	disrupt	VBD
cord-003130-p2h8p5bm	255	20	its	-PRON-	PRP$
cord-003130-p2h8p5bm	255	21	surface	surface	NN
cord-003130-p2h8p5bm	255	22	expression	expression	NN
cord-003130-p2h8p5bm	255	23	(	(	-LRB-
cord-003130-p2h8p5bm	255	24	Figure	figure	NN
cord-003130-p2h8p5bm	255	25	4B	4b	CD
cord-003130-p2h8p5bm	255	26	)	)	-RRB-
cord-003130-p2h8p5bm	255	27	[	[	-LRB-
cord-003130-p2h8p5bm	255	28	179	179	CD
cord-003130-p2h8p5bm	255	29	,	,	,
cord-003130-p2h8p5bm	255	30	182	182	CD
cord-003130-p2h8p5bm	255	31	]	]	-RRB-
cord-003130-p2h8p5bm	255	32	.	.	.
cord-003130-p2h8p5bm	256	1	In	in	IN
cord-003130-p2h8p5bm	256	2	KFDV	KFDV	NNP
cord-003130-p2h8p5bm	256	3	infection	infection	NN
cord-003130-p2h8p5bm	256	4	,	,	,
cord-003130-p2h8p5bm	256	5	IFN	IFN	NNP
cord-003130-p2h8p5bm	256	6	treatment	treatment	NN
cord-003130-p2h8p5bm	256	7	failed	fail	VBD
cord-003130-p2h8p5bm	256	8	to	to	TO
cord-003130-p2h8p5bm	256	9	reduce	reduce	VB
cord-003130-p2h8p5bm	256	10	viral	viral	JJ
cord-003130-p2h8p5bm	256	11	titers	titer	NNS
cord-003130-p2h8p5bm	256	12	when	when	WRB
cord-003130-p2h8p5bm	256	13	added	add	VBN
cord-003130-p2h8p5bm	256	14	after	after	IN
cord-003130-p2h8p5bm	256	15	infection	infection	NN
cord-003130-p2h8p5bm	256	16	,	,	,
cord-003130-p2h8p5bm	256	17	this	this	DT
cord-003130-p2h8p5bm	256	18	effect	effect	NN
cord-003130-p2h8p5bm	256	19	was	be	VBD
cord-003130-p2h8p5bm	256	20	also	also	RB
cord-003130-p2h8p5bm	256	21	found	find	VBN
cord-003130-p2h8p5bm	256	22	to	to	TO
cord-003130-p2h8p5bm	256	23	be	be	VB
cord-003130-p2h8p5bm	256	24	mediated	mediate	VBN
cord-003130-p2h8p5bm	256	25	by	by	IN
cord-003130-p2h8p5bm	256	26	the	the	DT
cord-003130-p2h8p5bm	256	27	NS5	ns5	JJ
cord-003130-p2h8p5bm	256	28	proteins	protein	NNS
cord-003130-p2h8p5bm	256	29	antagonism	antagonism	NN
cord-003130-p2h8p5bm	256	30	[	[	-LRB-
cord-003130-p2h8p5bm	256	31	180	180	CD
cord-003130-p2h8p5bm	256	32	,	,	,
cord-003130-p2h8p5bm	256	33	183	183	CD
cord-003130-p2h8p5bm	256	34	]	]	-RRB-
cord-003130-p2h8p5bm	256	35	.	.	.
cord-003130-p2h8p5bm	257	1	During	during	IN
cord-003130-p2h8p5bm	257	2	TBFV	TBFV	NNP
cord-003130-p2h8p5bm	257	3	infection	infection	NN
cord-003130-p2h8p5bm	257	4	,	,	,
cord-003130-p2h8p5bm	257	5	a	a	DT
cord-003130-p2h8p5bm	257	6	subgenomic	subgenomic	NNP
cord-003130-p2h8p5bm	257	7	noncoding	noncoding	NNP
cord-003130-p2h8p5bm	257	8	RNA	RNA	NNP
cord-003130-p2h8p5bm	257	9	is	be	VBZ
cord-003130-p2h8p5bm	257	10	formed	form	VBN
cord-003130-p2h8p5bm	257	11	,	,	,
cord-003130-p2h8p5bm	257	12	called	call	VBN
cord-003130-p2h8p5bm	257	13	subgenomic	subgenomic	NNP
cord-003130-p2h8p5bm	257	14	flavivirus	flavivirus	NNP
cord-003130-p2h8p5bm	257	15	RNA	RNA	NNP
cord-003130-p2h8p5bm	257	16	(	(	-LRB-
cord-003130-p2h8p5bm	257	17	sfRNA	sfrna	NN
cord-003130-p2h8p5bm	257	18	)	)	-RRB-
cord-003130-p2h8p5bm	258	1	[	[	-LRB-
cord-003130-p2h8p5bm	258	2	93	93	CD
cord-003130-p2h8p5bm	258	3	,	,	,
cord-003130-p2h8p5bm	258	4	184	184	CD
cord-003130-p2h8p5bm	258	5	,	,	,
cord-003130-p2h8p5bm	258	6	185	185	CD
cord-003130-p2h8p5bm	258	7	]	]	-RRB-
cord-003130-p2h8p5bm	258	8	.	.	.
cord-003130-p2h8p5bm	259	1	It	-PRON-	PRP
cord-003130-p2h8p5bm	259	2	is	be	VBZ
cord-003130-p2h8p5bm	259	3	produced	produce	VBN
cord-003130-p2h8p5bm	259	4	as	as	IN
cord-003130-p2h8p5bm	259	5	a	a	DT
cord-003130-p2h8p5bm	259	6	product	product	NN
cord-003130-p2h8p5bm	259	7	of	of	IN
cord-003130-p2h8p5bm	259	8	incomplete	incomplete	JJ
cord-003130-p2h8p5bm	259	9	degradation	degradation	NN
cord-003130-p2h8p5bm	259	10	of	of	IN
cord-003130-p2h8p5bm	259	11	genomic	genomic	JJ
cord-003130-p2h8p5bm	259	12	viral	viral	JJ
cord-003130-p2h8p5bm	259	13	RNA	RNA	NNP
cord-003130-p2h8p5bm	259	14	by	by	IN
cord-003130-p2h8p5bm	259	15	cellular	cellular	JJ
cord-003130-p2h8p5bm	259	16	5	5	CD
cord-003130-p2h8p5bm	260	1	-3	-3	NNP
cord-003130-p2h8p5bm	261	1	exoribonuclease	exoribonuclease	NNP
cord-003130-p2h8p5bm	261	2	XRN1	XRN1	NNP
cord-003130-p2h8p5bm	261	3	[	[	-LRB-
cord-003130-p2h8p5bm	261	4	184	184	CD
cord-003130-p2h8p5bm	261	5	]	]	-RRB-
cord-003130-p2h8p5bm	261	6	.	.	.
cord-003130-p2h8p5bm	262	1	The	the	DT
cord-003130-p2h8p5bm	262	2	ability	ability	NN
cord-003130-p2h8p5bm	262	3	to	to	TO
cord-003130-p2h8p5bm	262	4	produce	produce	VB
cord-003130-p2h8p5bm	262	5	sfRNA	sfRNA	NNS
cord-003130-p2h8p5bm	262	6	in	in	IN
cord-003130-p2h8p5bm	262	7	WNV	WNV	NNP
cord-003130-p2h8p5bm	262	8	was	be	VBD
cord-003130-p2h8p5bm	262	9	shown	show	VBN
cord-003130-p2h8p5bm	262	10	to	to	TO
cord-003130-p2h8p5bm	262	11	be	be	VB
cord-003130-p2h8p5bm	262	12	needed	need	VBN
cord-003130-p2h8p5bm	262	13	for	for	IN
cord-003130-p2h8p5bm	262	14	efficient	efficient	JJ
cord-003130-p2h8p5bm	262	15	viral	viral	JJ
cord-003130-p2h8p5bm	262	16	growth	growth	NN
cord-003130-p2h8p5bm	262	17	in	in	IN
cord-003130-p2h8p5bm	262	18	vitro	vitro	FW
cord-003130-p2h8p5bm	262	19	and	and	CC
cord-003130-p2h8p5bm	262	20	for	for	IN
cord-003130-p2h8p5bm	262	21	pathogenicity	pathogenicity	NN
cord-003130-p2h8p5bm	262	22	in	in	IN
cord-003130-p2h8p5bm	262	23	mice	mouse	NNS
cord-003130-p2h8p5bm	262	24	[	[	-LRB-
cord-003130-p2h8p5bm	262	25	184	184	CD
cord-003130-p2h8p5bm	262	26	]	]	-RRB-
cord-003130-p2h8p5bm	262	27	.	.	.
cord-003130-p2h8p5bm	263	1	Interestingly	interestingly	RB
cord-003130-p2h8p5bm	263	2	,	,	,
cord-003130-p2h8p5bm	263	3	DENV	DENV	NNP
cord-003130-p2h8p5bm	263	4	sfRNA	sfrna	NN
cord-003130-p2h8p5bm	263	5	was	be	VBD
cord-003130-p2h8p5bm	263	6	found	find	VBN
cord-003130-p2h8p5bm	263	7	to	to	TO
cord-003130-p2h8p5bm	263	8	bind	bind	VB
cord-003130-p2h8p5bm	263	9	to	to	IN
cord-003130-p2h8p5bm	263	10	TRIM25	TRIM25	NNP
cord-003130-p2h8p5bm	263	11	to	to	TO
cord-003130-p2h8p5bm	263	12	inhibit	inhibit	VB
cord-003130-p2h8p5bm	263	13	RIG	rig	NN
cord-003130-p2h8p5bm	263	14	-	-	HYPH
cord-003130-p2h8p5bm	263	15	I	i	NN
cord-003130-p2h8p5bm	263	16	-	-	HYPH
cord-003130-p2h8p5bm	263	17	induced	induce	VBN
cord-003130-p2h8p5bm	263	18	type	type	NN
cord-003130-p2h8p5bm	264	1	I	-PRON-	PRP
cord-003130-p2h8p5bm	264	2	interferon	interferon	VBD
cord-003130-p2h8p5bm	264	3	expression	expression	NN
cord-003130-p2h8p5bm	264	4	in	in	IN
cord-003130-p2h8p5bm	264	5	Huh-7	Huh-7	NNP
cord-003130-p2h8p5bm	264	6	cells	cell	NNS
cord-003130-p2h8p5bm	264	7	[	[	-LRB-
cord-003130-p2h8p5bm	264	8	186	186	CD
cord-003130-p2h8p5bm	264	9	]	]	-RRB-
cord-003130-p2h8p5bm	264	10	.	.	.
cord-003130-p2h8p5bm	265	1	Furthermore	furthermore	RB
cord-003130-p2h8p5bm	265	2	,	,	,
cord-003130-p2h8p5bm	265	3	DENV	DENV	NNP
cord-003130-p2h8p5bm	265	4	and	and	CC
cord-003130-p2h8p5bm	265	5	WNV	WNV	NNP
cord-003130-p2h8p5bm	265	6	sfRNA	sfRNA	NNS
cord-003130-p2h8p5bm	265	7	was	be	VBD
cord-003130-p2h8p5bm	265	8	found	find	VBN
cord-003130-p2h8p5bm	265	9	to	to	TO
cord-003130-p2h8p5bm	265	10	suppress	suppress	VB
cord-003130-p2h8p5bm	265	11	the	the	DT
cord-003130-p2h8p5bm	265	12	RNAi	RNAi	NNP
cord-003130-p2h8p5bm	265	13	response	response	NN
cord-003130-p2h8p5bm	265	14	in	in	IN
cord-003130-p2h8p5bm	265	15	both	both	DT
cord-003130-p2h8p5bm	265	16	mammalian	mammalian	JJ
cord-003130-p2h8p5bm	265	17	and	and	CC
cord-003130-p2h8p5bm	265	18	insect	insect	NN
cord-003130-p2h8p5bm	265	19	cells	cell	NNS
cord-003130-p2h8p5bm	265	20	[	[	-LRB-
cord-003130-p2h8p5bm	265	21	187	187	CD
cord-003130-p2h8p5bm	265	22	]	]	-RRB-
cord-003130-p2h8p5bm	265	23	.	.	.
cord-003130-p2h8p5bm	266	1	Similarly	similarly	RB
cord-003130-p2h8p5bm	266	2	,	,	,
cord-003130-p2h8p5bm	266	3	in	in	IN
cord-003130-p2h8p5bm	266	4	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	266	5	infection	infection	NN
cord-003130-p2h8p5bm	266	6	,	,	,
cord-003130-p2h8p5bm	266	7	sfRNA	sfrna	NN
cord-003130-p2h8p5bm	266	8	has	have	VBZ
cord-003130-p2h8p5bm	266	9	been	be	VBN
cord-003130-p2h8p5bm	266	10	demonstrated	demonstrate	VBN
cord-003130-p2h8p5bm	266	11	to	to	TO
cord-003130-p2h8p5bm	266	12	inhibit	inhibit	VB
cord-003130-p2h8p5bm	266	13	the	the	DT
cord-003130-p2h8p5bm	266	14	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	266	15	RNAi	RNAi	NNP
cord-003130-p2h8p5bm	266	16	response	response	NN
cord-003130-p2h8p5bm	266	17	in	in	IN
cord-003130-p2h8p5bm	266	18	tick	tick	NN
cord-003130-p2h8p5bm	266	19	cells	cell	NNS
cord-003130-p2h8p5bm	266	20	[	[	-LRB-
cord-003130-p2h8p5bm	266	21	93	93	CD
cord-003130-p2h8p5bm	266	22	]	]	-RRB-
cord-003130-p2h8p5bm	266	23	.	.	.
cord-003130-p2h8p5bm	267	1	PEPD	PEPD	NNP
cord-003130-p2h8p5bm	267	2	is	be	VBZ
cord-003130-p2h8p5bm	267	3	needed	need	VBN
cord-003130-p2h8p5bm	267	4	for	for	IN
cord-003130-p2h8p5bm	267	5	maturation	maturation	NN
cord-003130-p2h8p5bm	267	6	and	and	CC
cord-003130-p2h8p5bm	267	7	subsequent	subsequent	JJ
cord-003130-p2h8p5bm	267	8	transport	transport	NN
cord-003130-p2h8p5bm	267	9	of	of	IN
cord-003130-p2h8p5bm	267	10	IFNAR1	ifnar1	NN
cord-003130-p2h8p5bm	267	11	to	to	IN
cord-003130-p2h8p5bm	267	12	the	the	DT
cord-003130-p2h8p5bm	267	13	plasma	plasma	NN
cord-003130-p2h8p5bm	267	14	membrane	membrane	NN
cord-003130-p2h8p5bm	267	15	.	.	.
cord-003130-p2h8p5bm	268	1	IFNAR1	IFNAR1	NNP
cord-003130-p2h8p5bm	268	2	and	and	CC
cord-003130-p2h8p5bm	268	3	IFNAR2	IFNAR2	NNP
cord-003130-p2h8p5bm	269	1	heterodimer	heterodimer	NN
cord-003130-p2h8p5bm	269	2	on	on	IN
cord-003130-p2h8p5bm	269	3	plasma	plasma	NN
cord-003130-p2h8p5bm	269	4	membrane	membrane	NN
cord-003130-p2h8p5bm	269	5	can	can	MD
cord-003130-p2h8p5bm	269	6	be	be	VB
cord-003130-p2h8p5bm	269	7	activated	activate	VBN
cord-003130-p2h8p5bm	269	8	by	by	IN
cord-003130-p2h8p5bm	269	9	IFNα	IFNα	NNP
cord-003130-p2h8p5bm	269	10	/	/	SYM
cord-003130-p2h8p5bm	269	11	β	β	NN
cord-003130-p2h8p5bm	269	12	which	which	WDT
cord-003130-p2h8p5bm	269	13	leads	lead	VBZ
cord-003130-p2h8p5bm	269	14	to	to	IN
cord-003130-p2h8p5bm	269	15	the	the	DT
cord-003130-p2h8p5bm	269	16	signaling	signal	VBG
cord-003130-p2h8p5bm	269	17	cascade	cascade	NN
cord-003130-p2h8p5bm	269	18	and	and	CC
cord-003130-p2h8p5bm	269	19	phosphorylation	phosphorylation	NN
cord-003130-p2h8p5bm	269	20	and	and	CC
cord-003130-p2h8p5bm	269	21	translocation	translocation	NN
cord-003130-p2h8p5bm	269	22	of	of	IN
cord-003130-p2h8p5bm	269	23	STAT1/2-IRF9	STAT1/2-IRF9	NNS
cord-003130-p2h8p5bm	269	24	into	into	IN
cord-003130-p2h8p5bm	269	25	the	the	DT
cord-003130-p2h8p5bm	269	26	nucleus	nucleus	NN
cord-003130-p2h8p5bm	269	27	and	and	CC
cord-003130-p2h8p5bm	269	28	upregulation	upregulation	NN
cord-003130-p2h8p5bm	269	29	of	of	IN
cord-003130-p2h8p5bm	269	30	ISGs	isg	NNS
cord-003130-p2h8p5bm	269	31	.	.	.
cord-003130-p2h8p5bm	270	1	Right	right	JJ
cord-003130-p2h8p5bm	270	2	panel	panel	NN
cord-003130-p2h8p5bm	270	3	:	:	:
cord-003130-p2h8p5bm	270	4	NS5	NS5	NNP
cord-003130-p2h8p5bm	270	5	interferes	interfere	VBZ
cord-003130-p2h8p5bm	270	6	with	with	IN
cord-003130-p2h8p5bm	270	7	IFN	IFN	NNP
cord-003130-p2h8p5bm	270	8	signaling	signal	VBG
cord-003130-p2h8p5bm	270	9	.	.	.
cord-003130-p2h8p5bm	271	1	NS5	ns5	JJ
cord-003130-p2h8p5bm	271	2	protein	protein	NN
cord-003130-p2h8p5bm	271	3	interacts	interact	VBZ
cord-003130-p2h8p5bm	271	4	with	with	IN
cord-003130-p2h8p5bm	271	5	PEPD	PEPD	NNP
cord-003130-p2h8p5bm	271	6	thus	thus	RB
cord-003130-p2h8p5bm	271	7	preventing	prevent	VBG
cord-003130-p2h8p5bm	271	8	IFNAR1	IFNAR1	``
cord-003130-p2h8p5bm	271	9	plasma	plasma	NN
cord-003130-p2h8p5bm	271	10	membrane	membrane	NN
cord-003130-p2h8p5bm	271	11	localization	localization	NN
cord-003130-p2h8p5bm	271	12	(	(	-LRB-
cord-003130-p2h8p5bm	271	13	red	red	JJ
cord-003130-p2h8p5bm	271	14	T	T	NNP
cord-003130-p2h8p5bm	271	15	)	)	-RRB-
cord-003130-p2h8p5bm	271	16	.	.	.
cord-003130-p2h8p5bm	272	1	NS5	NS5	NNP
cord-003130-p2h8p5bm	272	2	also	also	RB
cord-003130-p2h8p5bm	272	3	prevents	prevent	VBZ
cord-003130-p2h8p5bm	272	4	STAT1	stat1	NN
cord-003130-p2h8p5bm	272	5	phosphorylation	phosphorylation	NN
cord-003130-p2h8p5bm	272	6	(	(	-LRB-
cord-003130-p2h8p5bm	272	7	red	red	JJ
cord-003130-p2h8p5bm	272	8	T	T	NNP
cord-003130-p2h8p5bm	272	9	)	)	-RRB-
cord-003130-p2h8p5bm	272	10	.	.	.
cord-003130-p2h8p5bm	273	1	Arrows	arrow	NNS
cord-003130-p2h8p5bm	273	2	indicate	indicate	VBP
cord-003130-p2h8p5bm	273	3	protein	protein	NN
cord-003130-p2h8p5bm	273	4	transport	transport	NN
cord-003130-p2h8p5bm	273	5	.	.	.
cord-003130-p2h8p5bm	274	1	Even	even	RB
cord-003130-p2h8p5bm	274	2	though	though	IN
cord-003130-p2h8p5bm	274	3	recent	recent	JJ
cord-003130-p2h8p5bm	274	4	studies	study	NNS
cord-003130-p2h8p5bm	274	5	have	have	VBP
cord-003130-p2h8p5bm	274	6	shed	shed	VBN
cord-003130-p2h8p5bm	274	7	light	light	NN
cord-003130-p2h8p5bm	274	8	on	on	IN
cord-003130-p2h8p5bm	274	9	the	the	DT
cord-003130-p2h8p5bm	274	10	role	role	NN
cord-003130-p2h8p5bm	274	11	of	of	IN
cord-003130-p2h8p5bm	274	12	innate	innate	JJ
cord-003130-p2h8p5bm	274	13	immunity	immunity	NN
cord-003130-p2h8p5bm	274	14	during	during	IN
cord-003130-p2h8p5bm	274	15	tick	tick	NN
cord-003130-p2h8p5bm	274	16	-	-	HYPH
cord-003130-p2h8p5bm	274	17	borne	bear	VBN
cord-003130-p2h8p5bm	274	18	flavivirus	flavivirus	JJ
cord-003130-p2h8p5bm	274	19	infection	infection	NN
cord-003130-p2h8p5bm	274	20	,	,	,
cord-003130-p2h8p5bm	274	21	much	much	RB
cord-003130-p2h8p5bm	274	22	remains	remain	VBZ
cord-003130-p2h8p5bm	274	23	unknown	unknown	JJ
cord-003130-p2h8p5bm	274	24	.	.	.
cord-003130-p2h8p5bm	275	1	For	for	IN
cord-003130-p2h8p5bm	275	2	example	example	NN
cord-003130-p2h8p5bm	275	3	,	,	,
cord-003130-p2h8p5bm	275	4	the	the	DT
cord-003130-p2h8p5bm	275	5	role	role	NN
cord-003130-p2h8p5bm	275	6	of	of	IN
cord-003130-p2h8p5bm	275	7	the	the	DT
cord-003130-p2h8p5bm	275	8	TLR	TLR	NNP
cord-003130-p2h8p5bm	275	9	-	-	HYPH
cord-003130-p2h8p5bm	275	10	TRIF	TRIF	NNP
cord-003130-p2h8p5bm	275	11	and	and	CC
cord-003130-p2h8p5bm	275	12	TLR	TLR	NNP
cord-003130-p2h8p5bm	275	13	-	-	HYPH
cord-003130-p2h8p5bm	275	14	MyD88	MyD88	NNP
cord-003130-p2h8p5bm	275	15	pathway	pathway	NN
cord-003130-p2h8p5bm	275	16	in	in	IN
cord-003130-p2h8p5bm	275	17	pathogenesis	pathogenesis	NN
cord-003130-p2h8p5bm	275	18	and	and	CC
cord-003130-p2h8p5bm	275	19	viral	viral	JJ
cord-003130-p2h8p5bm	275	20	recognition	recognition	NN
cord-003130-p2h8p5bm	275	21	.	.	.
cord-003130-p2h8p5bm	276	1	Furthermore	furthermore	RB
cord-003130-p2h8p5bm	276	2	,	,	,
cord-003130-p2h8p5bm	276	3	most	most	JJS
cord-003130-p2h8p5bm	276	4	studies	study	NNS
cord-003130-p2h8p5bm	276	5	were	be	VBD
cord-003130-p2h8p5bm	276	6	performed	perform	VBN
cord-003130-p2h8p5bm	276	7	using	use	VBG
cord-003130-p2h8p5bm	276	8	LGTV	LGTV	NNP
cord-003130-p2h8p5bm	276	9	and	and	CC
cord-003130-p2h8p5bm	276	10	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	276	11	,	,	,
cord-003130-p2h8p5bm	276	12	and	and	CC
cord-003130-p2h8p5bm	276	13	although	although	IN
cord-003130-p2h8p5bm	276	14	they	-PRON-	PRP
cord-003130-p2h8p5bm	276	15	are	be	VBP
cord-003130-p2h8p5bm	276	16	closely	closely	RB
cord-003130-p2h8p5bm	276	17	related	related	JJ
cord-003130-p2h8p5bm	276	18	to	to	IN
cord-003130-p2h8p5bm	276	19	POWV	POWV	NNP
cord-003130-p2h8p5bm	276	20	,	,	,
cord-003130-p2h8p5bm	276	21	LIV	LIV	NNP
cord-003130-p2h8p5bm	276	22	,	,	,
cord-003130-p2h8p5bm	276	23	KFDV	KFDV	NNP
cord-003130-p2h8p5bm	276	24	,	,	,
cord-003130-p2h8p5bm	276	25	and	and	CC
cord-003130-p2h8p5bm	276	26	OHFV	OHFV	NNP
cord-003130-p2h8p5bm	276	27	,	,	,
cord-003130-p2h8p5bm	276	28	their	-PRON-	PRP$
cord-003130-p2h8p5bm	276	29	interactions	interaction	NNS
cord-003130-p2h8p5bm	276	30	with	with	IN
cord-003130-p2h8p5bm	276	31	the	the	DT
cord-003130-p2h8p5bm	276	32	innate	innate	JJ
cord-003130-p2h8p5bm	276	33	immune	immune	JJ
cord-003130-p2h8p5bm	276	34	response	response	NN
cord-003130-p2h8p5bm	276	35	might	may	MD
cord-003130-p2h8p5bm	276	36	differ	differ	VB
cord-003130-p2h8p5bm	276	37	.	.	.
cord-003130-p2h8p5bm	277	1	Although	although	IN
cord-003130-p2h8p5bm	277	2	IFN	IFN	NNP
cord-003130-p2h8p5bm	277	3	has	have	VBZ
cord-003130-p2h8p5bm	277	4	been	be	VBN
cord-003130-p2h8p5bm	277	5	shown	show	VBN
cord-003130-p2h8p5bm	277	6	to	to	TO
cord-003130-p2h8p5bm	277	7	strongly	strongly	RB
cord-003130-p2h8p5bm	277	8	control	control	VB
cord-003130-p2h8p5bm	277	9	viral	viral	JJ
cord-003130-p2h8p5bm	277	10	tropism	tropism	NN
cord-003130-p2h8p5bm	277	11	and	and	CC
cord-003130-p2h8p5bm	277	12	pathogenesis	pathogenesis	NN
cord-003130-p2h8p5bm	277	13	of	of	IN
cord-003130-p2h8p5bm	277	14	tick	tick	NN
cord-003130-p2h8p5bm	277	15	-	-	HYPH
cord-003130-p2h8p5bm	277	16	borne	bear	VBN
cord-003130-p2h8p5bm	277	17	flaviviruses	flavivirus	NNS
cord-003130-p2h8p5bm	277	18	,	,	,
cord-003130-p2h8p5bm	277	19	few	few	JJ
cord-003130-p2h8p5bm	277	20	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	277	21	ISGs	isg	NNS
cord-003130-p2h8p5bm	277	22	have	have	VBP
cord-003130-p2h8p5bm	277	23	been	be	VBN
cord-003130-p2h8p5bm	277	24	identified	identify	VBN
cord-003130-p2h8p5bm	277	25	.	.	.
cord-003130-p2h8p5bm	278	1	Viperin	Viperin	NNP
cord-003130-p2h8p5bm	278	2	has	have	VBZ
cord-003130-p2h8p5bm	278	3	been	be	VBN
cord-003130-p2h8p5bm	278	4	shown	show	VBN
cord-003130-p2h8p5bm	278	5	to	to	TO
cord-003130-p2h8p5bm	278	6	be	be	VB
cord-003130-p2h8p5bm	278	7	the	the	DT
cord-003130-p2h8p5bm	278	8	most	most	RBS
cord-003130-p2h8p5bm	278	9	important	important	JJ
cord-003130-p2h8p5bm	278	10	ISG	ISG	NNP
cord-003130-p2h8p5bm	278	11	in	in	IN
cord-003130-p2h8p5bm	278	12	cortical	cortical	JJ
cord-003130-p2h8p5bm	278	13	neurons	neuron	NNS
cord-003130-p2h8p5bm	278	14	,	,	,
cord-003130-p2h8p5bm	278	15	however	however	RB
cord-003130-p2h8p5bm	278	16	,	,	,
cord-003130-p2h8p5bm	278	17	other	other	JJ
cord-003130-p2h8p5bm	278	18	ISGs	isg	NNS
cord-003130-p2h8p5bm	278	19	that	that	WDT
cord-003130-p2h8p5bm	278	20	target	target	VBP
cord-003130-p2h8p5bm	278	21	TBEV	TBEV	NNP
cord-003130-p2h8p5bm	278	22	expressed	express	VBD
cord-003130-p2h8p5bm	278	23	in	in	IN
cord-003130-p2h8p5bm	278	24	astrocytes	astrocyte	NNS
cord-003130-p2h8p5bm	278	25	and	and	CC
cord-003130-p2h8p5bm	278	26	granular	granular	JJ
cord-003130-p2h8p5bm	278	27	cell	cell	NN
cord-003130-p2h8p5bm	278	28	neurons	neuron	NNS
cord-003130-p2h8p5bm	278	29	are	be	VBP
cord-003130-p2h8p5bm	278	30	yet	yet	RB
cord-003130-p2h8p5bm	278	31	to	to	TO
cord-003130-p2h8p5bm	278	32	be	be	VB
cord-003130-p2h8p5bm	278	33	identified	identify	VBN
cord-003130-p2h8p5bm	278	34	and	and	CC
cord-003130-p2h8p5bm	278	35	very	very	RB
cord-003130-p2h8p5bm	278	36	little	little	JJ
cord-003130-p2h8p5bm	278	37	is	be	VBZ
cord-003130-p2h8p5bm	278	38	known	know	VBN
cord-003130-p2h8p5bm	278	39	about	about	IN
cord-003130-p2h8p5bm	278	40	the	the	DT
cord-003130-p2h8p5bm	278	41	early	early	JJ
cord-003130-p2h8p5bm	278	42	response	response	NN
cord-003130-p2h8p5bm	278	43	against	against	IN
cord-003130-p2h8p5bm	278	44	the	the	DT
cord-003130-p2h8p5bm	278	45	hemorrhagic	hemorrhagic	JJ
cord-003130-p2h8p5bm	278	46	TBFVs	tbfv	NNS
cord-003130-p2h8p5bm	278	47	.	.	.
cord-003130-p2h8p5bm	279	1	We	-PRON-	PRP
cord-003130-p2h8p5bm	279	2	also	also	RB
cord-003130-p2h8p5bm	279	3	know	know	VBP
cord-003130-p2h8p5bm	279	4	very	very	RB
cord-003130-p2h8p5bm	279	5	little	little	JJ
cord-003130-p2h8p5bm	279	6	about	about	IN
cord-003130-p2h8p5bm	279	7	how	how	WRB
cord-003130-p2h8p5bm	279	8	the	the	DT
cord-003130-p2h8p5bm	279	9	innate	innate	JJ
cord-003130-p2h8p5bm	279	10	immune	immune	JJ
cord-003130-p2h8p5bm	279	11	response	response	NN
cord-003130-p2h8p5bm	279	12	regulates	regulate	VBZ
cord-003130-p2h8p5bm	279	13	the	the	DT
cord-003130-p2h8p5bm	279	14	neuroinvasion	neuroinvasion	NN
cord-003130-p2h8p5bm	279	15	of	of	IN
cord-003130-p2h8p5bm	279	16	neurotropic	neurotropic	NNP
cord-003130-p2h8p5bm	279	17	TBFV	TBFV	NNP
cord-003130-p2h8p5bm	279	18	,	,	,
cord-003130-p2h8p5bm	279	19	and	and	CC
cord-003130-p2h8p5bm	279	20	the	the	DT
cord-003130-p2h8p5bm	279	21	specific	specific	JJ
cord-003130-p2h8p5bm	279	22	interactions	interaction	NNS
cord-003130-p2h8p5bm	279	23	between	between	IN
cord-003130-p2h8p5bm	279	24	the	the	DT
cord-003130-p2h8p5bm	279	25	tick	tick	NN
cord-003130-p2h8p5bm	279	26	vector	vector	NN
cord-003130-p2h8p5bm	279	27	and	and	CC
cord-003130-p2h8p5bm	279	28	the	the	DT
cord-003130-p2h8p5bm	279	29	different	different	JJ
cord-003130-p2h8p5bm	279	30	viruses	virus	NNS
cord-003130-p2h8p5bm	279	31	.	.	.
cord-003130-p2h8p5bm	279	32	 	 	_SP
cord-003130-p2h8p5bm	280	1	Emergence	emergence	NN
cord-003130-p2h8p5bm	280	2	and	and	CC
cord-003130-p2h8p5bm	280	3	spreading	spread	VBG
cord-003130-p2h8p5bm	280	4	potential	potential	NN
cord-003130-p2h8p5bm	280	5	of	of	IN
cord-003130-p2h8p5bm	280	6	zika	zika	NNP
cord-003130-p2h8p5bm	280	7	virus	virus	NN
cord-003130-p2h8p5bm	280	8	Dengue	Dengue	NNP
cord-003130-p2h8p5bm	280	9	virus	virus	NN
cord-003130-p2h8p5bm	280	10	:	:	:
cord-003130-p2h8p5bm	280	11	A	a	DT
cord-003130-p2h8p5bm	280	12	global	global	JJ
cord-003130-p2h8p5bm	280	13	human	human	JJ
cord-003130-p2h8p5bm	280	14	threat	threat	NN
cord-003130-p2h8p5bm	280	15	:	:	:
cord-003130-p2h8p5bm	280	16	Review	Review	NNP
cord-003130-p2h8p5bm	280	17	of	of	IN
cord-003130-p2h8p5bm	280	18	literature	literature	NNP
cord-003130-p2h8p5bm	280	19	West	West	NNP
cord-003130-p2h8p5bm	280	20	nile	nile	NNP
cord-003130-p2h8p5bm	280	21	virus	virus	NN
cord-003130-p2h8p5bm	280	22	:	:	:
cord-003130-p2h8p5bm	280	23	A	a	DT
cord-003130-p2h8p5bm	280	24	re	re	NN
cord-003130-p2h8p5bm	280	25	-	-	JJ
cord-003130-p2h8p5bm	280	26	emerging	emerge	VBG
cord-003130-p2h8p5bm	280	27	pathogen	pathogen	NN
cord-003130-p2h8p5bm	280	28	revisited	revisit	VBD
cord-003130-p2h8p5bm	280	29	Alphaviruses	Alphaviruses	NNP
cord-003130-p2h8p5bm	280	30	(	(	-LRB-
cord-003130-p2h8p5bm	280	31	togaviridae	togaviridae	NNP
cord-003130-p2h8p5bm	280	32	)	)	-RRB-
cord-003130-p2h8p5bm	280	33	and	and	CC
cord-003130-p2h8p5bm	280	34	flaviviruses	flaviviruses	NNP
cord-003130-p2h8p5bm	280	35	(	(	-LRB-
cord-003130-p2h8p5bm	280	36	flaviviridae	flaviviridae	NNP
cord-003130-p2h8p5bm	280	37	)	)	-RRB-
cord-003130-p2h8p5bm	280	38	Hepatitis	Hepatitis	NNP
cord-003130-p2h8p5bm	280	39	C	C	NNP
cord-003130-p2h8p5bm	280	40	virus	virus	NN
cord-003130-p2h8p5bm	280	41	:	:	:
cord-003130-p2h8p5bm	280	42	Virology	virology	NN
cord-003130-p2h8p5bm	280	43	and	and	CC
cord-003130-p2h8p5bm	280	44	life	life	NN
cord-003130-p2h8p5bm	280	45	cycle	cycle	NN
cord-003130-p2h8p5bm	280	46	Characteristics	characteristic	NNS
cord-003130-p2h8p5bm	280	47	of	of	IN
cord-003130-p2h8p5bm	280	48	a	a	DT
cord-003130-p2h8p5bm	280	49	nidus	nidus	NN
cord-003130-p2h8p5bm	280	50	of	of	IN
cord-003130-p2h8p5bm	280	51	tick	tick	NN
cord-003130-p2h8p5bm	280	52	-	-	HYPH
cord-003130-p2h8p5bm	280	53	borne	bear	VBN
cord-003130-p2h8p5bm	280	54	encephalitis	encephalitis	RB
cord-003130-p2h8p5bm	280	55	in	in	IN
cord-003130-p2h8p5bm	280	56	the	the	DT
cord-003130-p2h8p5bm	280	57	construction	construction	NN
cord-003130-p2h8p5bm	280	58	zone	zone	NN
cord-003130-p2h8p5bm	280	59	of	of	IN
cord-003130-p2h8p5bm	280	60	the	the	DT
cord-003130-p2h8p5bm	280	61	krasnoyarsk	krasnoyarsk	NNP
cord-003130-p2h8p5bm	280	62	hydroelectric	hydroelectric	NNP
cord-003130-p2h8p5bm	280	63	station	station	NN
cord-003130-p2h8p5bm	280	64	and	and	CC
cord-003130-p2h8p5bm	280	65	development	development	NN
cord-003130-p2h8p5bm	280	66	of	of	IN
cord-003130-p2h8p5bm	280	67	measures	measure	NNS
cord-003130-p2h8p5bm	280	68	for	for	IN
cord-003130-p2h8p5bm	280	69	protection	protection	NN
cord-003130-p2h8p5bm	280	70	of	of	IN
cord-003130-p2h8p5bm	280	71	workers	worker	NNS
cord-003130-p2h8p5bm	280	72	against	against	IN
cord-003130-p2h8p5bm	280	73	ticks	tick	NNS
cord-003130-p2h8p5bm	280	74	;	;	:
cord-003130-p2h8p5bm	281	1	preliminary	preliminary	JJ
cord-003130-p2h8p5bm	281	2	report	report	NN
cord-003130-p2h8p5bm	282	1	Stable	stable	JJ
cord-003130-p2h8p5bm	282	2	prevalence	prevalence	NN
cord-003130-p2h8p5bm	282	3	of	of	IN
cord-003130-p2h8p5bm	282	4	powassan	powassan	NNP
cord-003130-p2h8p5bm	282	5	virus	virus	NN
cord-003130-p2h8p5bm	282	6	in	in	IN
cord-003130-p2h8p5bm	282	7	ixodes	ixodes	NNP
cord-003130-p2h8p5bm	282	8	scapularis	scapularis	NNP
cord-003130-p2h8p5bm	282	9	in	in	IN
cord-003130-p2h8p5bm	282	10	a	a	DT
cord-003130-p2h8p5bm	282	11	northern	northern	JJ
cord-003130-p2h8p5bm	282	12	wisconsin	wisconsin	NNP
cord-003130-p2h8p5bm	282	13	focus	focus	VB
cord-003130-p2h8p5bm	282	14	A	a	DT
cord-003130-p2h8p5bm	282	15	global	global	JJ
cord-003130-p2h8p5bm	282	16	perspective	perspective	NN
cord-003130-p2h8p5bm	282	17	on	on	IN
cord-003130-p2h8p5bm	282	18	the	the	DT
cord-003130-p2h8p5bm	282	19	epidemiology	epidemiology	NN
cord-003130-p2h8p5bm	282	20	of	of	IN
cord-003130-p2h8p5bm	282	21	west	west	NNP
cord-003130-p2h8p5bm	282	22	nile	nile	NNP
cord-003130-p2h8p5bm	282	23	virus	virus	NN
cord-003130-p2h8p5bm	282	24	Zika	Zika	NNP
cord-003130-p2h8p5bm	282	25	virus	virus	NN
cord-003130-p2h8p5bm	282	26	:	:	:
cord-003130-p2h8p5bm	283	1	New	new	JJ
cord-003130-p2h8p5bm	283	2	clinical	clinical	JJ
cord-003130-p2h8p5bm	283	3	syndromes	syndrome	NNS
cord-003130-p2h8p5bm	283	4	and	and	CC
cord-003130-p2h8p5bm	283	5	its	-PRON-	PRP$
cord-003130-p2h8p5bm	283	6	emergence	emergence	NN
cord-003130-p2h8p5bm	283	7	in	in	IN
cord-003130-p2h8p5bm	283	8	the	the	DT
cord-003130-p2h8p5bm	283	9	western	western	JJ
cord-003130-p2h8p5bm	283	10	hemisphere	hemisphere	NN
cord-003130-p2h8p5bm	283	11	West	West	NNP
cord-003130-p2h8p5bm	283	12	nile	nile	NNP
cord-003130-p2h8p5bm	283	13	virus	virus	NN
cord-003130-p2h8p5bm	283	14	and	and	CC
cord-003130-p2h8p5bm	283	15	its	-PRON-	PRP$
cord-003130-p2h8p5bm	283	16	emergence	emergence	NN
cord-003130-p2h8p5bm	283	17	in	in	IN
cord-003130-p2h8p5bm	283	18	the	the	DT
cord-003130-p2h8p5bm	283	19	united	united	NNP
cord-003130-p2h8p5bm	283	20	states	states	NNP
cord-003130-p2h8p5bm	283	21	of	of	IN
cord-003130-p2h8p5bm	283	22	america	america	NNP
cord-003130-p2h8p5bm	283	23	Flavivirus	Flavivirus	NNP
cord-003130-p2h8p5bm	283	24	encephalitis	encephalitis	RB
cord-003130-p2h8p5bm	284	1	The	the	DT
cord-003130-p2h8p5bm	284	2	changing	change	VBG
cord-003130-p2h8p5bm	284	3	epidemiology	epidemiology	NN
cord-003130-p2h8p5bm	284	4	of	of	IN
cord-003130-p2h8p5bm	284	5	yellow	yellow	JJ
cord-003130-p2h8p5bm	284	6	fever	fever	NN
cord-003130-p2h8p5bm	284	7	and	and	CC
cord-003130-p2h8p5bm	284	8	dengue	dengue	NN
cord-003130-p2h8p5bm	284	9	Yellow	yellow	JJ
cord-003130-p2h8p5bm	284	10	fever	fever	NN
cord-003130-p2h8p5bm	284	11	:	:	:
cord-003130-p2h8p5bm	285	1	A	a	DT
cord-003130-p2h8p5bm	285	2	disease	disease	NN
cord-003130-p2h8p5bm	285	3	that	that	WDT
cord-003130-p2h8p5bm	285	4	has	have	VBZ
cord-003130-p2h8p5bm	285	5	yet	yet	RB
cord-003130-p2h8p5bm	285	6	to	to	TO
cord-003130-p2h8p5bm	285	7	be	be	VB
cord-003130-p2h8p5bm	285	8	conquered	conquer	VBN
cord-003130-p2h8p5bm	285	9	Modes	Modes	NNPS
cord-003130-p2h8p5bm	285	10	of	of	IN
cord-003130-p2h8p5bm	285	11	transmission	transmission	NN
cord-003130-p2h8p5bm	285	12	of	of	IN
cord-003130-p2h8p5bm	285	13	zika	zika	NNP
cord-003130-p2h8p5bm	285	14	virus	virus	NN
cord-003130-p2h8p5bm	285	15	Ticks	Ticks	NNPS
cord-003130-p2h8p5bm	285	16	and	and	CC
cord-003130-p2h8p5bm	285	17	tickborne	tickborne	VBZ
cord-003130-p2h8p5bm	285	18	bacterial	bacterial	JJ
cord-003130-p2h8p5bm	285	19	diseases	disease	NNS
cord-003130-p2h8p5bm	285	20	in	in	IN
cord-003130-p2h8p5bm	285	21	humans	human	NNS
cord-003130-p2h8p5bm	285	22	:	:	:
cord-003130-p2h8p5bm	286	1	An	an	DT
cord-003130-p2h8p5bm	286	2	emerging	emerge	VBG
cord-003130-p2h8p5bm	286	3	infectious	infectious	JJ
cord-003130-p2h8p5bm	286	4	threat	threat	NN
cord-003130-p2h8p5bm	286	5	Short	Short	NNP
cord-003130-p2h8p5bm	286	6	report	report	NN
cord-003130-p2h8p5bm	286	7	:	:	:
cord-003130-p2h8p5bm	286	8	Duration	duration	NN
cord-003130-p2h8p5bm	286	9	of	of	IN
cord-003130-p2h8p5bm	286	10	tick	tick	NN
cord-003130-p2h8p5bm	286	11	attachment	attachment	NN
cord-003130-p2h8p5bm	286	12	required	require	VBN
cord-003130-p2h8p5bm	286	13	for	for	IN
cord-003130-p2h8p5bm	286	14	transmission	transmission	NN
cord-003130-p2h8p5bm	286	15	of	of	IN
cord-003130-p2h8p5bm	286	16	powassan	powassan	NNP
cord-003130-p2h8p5bm	286	17	virus	virus	NN
cord-003130-p2h8p5bm	286	18	by	by	IN
cord-003130-p2h8p5bm	286	19	deer	deer	NN
cord-003130-p2h8p5bm	286	20	ticks	tick	NNS
cord-003130-p2h8p5bm	287	1	Zoonotic	zoonotic	JJ
cord-003130-p2h8p5bm	287	2	tick	tick	NN
cord-003130-p2h8p5bm	287	3	-	-	HYPH
cord-003130-p2h8p5bm	287	4	borne	bear	VBN
cord-003130-p2h8p5bm	287	5	flaviviruses	flavivirus	NNS
cord-003130-p2h8p5bm	288	1	Molecular	molecular	JJ
cord-003130-p2h8p5bm	288	2	characterization	characterization	NN
cord-003130-p2h8p5bm	288	3	of	of	IN
cord-003130-p2h8p5bm	288	4	tick	tick	NN
cord-003130-p2h8p5bm	288	5	-	-	HYPH
cord-003130-p2h8p5bm	288	6	virus	virus	NN
cord-003130-p2h8p5bm	288	7	interactions	interaction	NNS
cord-003130-p2h8p5bm	288	8	Dynamics	dynamic	NNS
cord-003130-p2h8p5bm	288	9	of	of	IN
cord-003130-p2h8p5bm	288	10	infection	infection	NN
cord-003130-p2h8p5bm	288	11	in	in	IN
cord-003130-p2h8p5bm	288	12	tick	tick	NN
cord-003130-p2h8p5bm	288	13	vectors	vector	NNS
cord-003130-p2h8p5bm	288	14	and	and	CC
cord-003130-p2h8p5bm	288	15	at	at	IN
cord-003130-p2h8p5bm	288	16	the	the	DT
cord-003130-p2h8p5bm	288	17	tick	tick	NN
cord-003130-p2h8p5bm	288	18	-	-	HYPH
cord-003130-p2h8p5bm	288	19	host	host	NN
cord-003130-p2h8p5bm	288	20	interface	interface	NN
cord-003130-p2h8p5bm	288	21	Non	non	JJ
cord-003130-p2h8p5bm	288	22	-	-	JJ
cord-003130-p2h8p5bm	288	23	viraemic	viraemic	JJ
cord-003130-p2h8p5bm	288	24	transmission	transmission	NN
cord-003130-p2h8p5bm	288	25	of	of	IN
cord-003130-p2h8p5bm	288	26	tick	tick	NN
cord-003130-p2h8p5bm	288	27	-	-	HYPH
cord-003130-p2h8p5bm	288	28	borne	bear	VBN
cord-003130-p2h8p5bm	288	29	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	288	30	virus	virus	NN
cord-003130-p2h8p5bm	288	31	:	:	:
cord-003130-p2h8p5bm	289	1	A	a	DT
cord-003130-p2h8p5bm	289	2	mechanism	mechanism	NN
cord-003130-p2h8p5bm	289	3	for	for	IN
cord-003130-p2h8p5bm	289	4	arbovirus	arbovirus	NN
cord-003130-p2h8p5bm	289	5	survival	survival	NN
cord-003130-p2h8p5bm	289	6	in	in	IN
cord-003130-p2h8p5bm	289	7	nature	nature	NN
cord-003130-p2h8p5bm	289	8	Sequence	sequence	NN
cord-003130-p2h8p5bm	289	9	analysis	analysis	NN
cord-003130-p2h8p5bm	289	10	and	and	CC
cord-003130-p2h8p5bm	289	11	genetic	genetic	JJ
cord-003130-p2h8p5bm	289	12	classification	classification	NN
cord-003130-p2h8p5bm	289	13	of	of	IN
cord-003130-p2h8p5bm	289	14	tick	tick	NN
cord-003130-p2h8p5bm	289	15	-	-	HYPH
cord-003130-p2h8p5bm	289	16	borne	bear	VBN
cord-003130-p2h8p5bm	289	17	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	289	18	viruses	virus	NNS
cord-003130-p2h8p5bm	289	19	from	from	IN
cord-003130-p2h8p5bm	289	20	europe	europe	NNP
cord-003130-p2h8p5bm	289	21	and	and	CC
cord-003130-p2h8p5bm	289	22	asia	asia	NNP
cord-003130-p2h8p5bm	289	23	Tick	Tick	NNP
cord-003130-p2h8p5bm	289	24	-	-	HYPH
cord-003130-p2h8p5bm	289	25	borne	bear	VBN
cord-003130-p2h8p5bm	289	26	flaviviruses	flavivirus	NNS
cord-003130-p2h8p5bm	289	27	Tick	tick	NN
cord-003130-p2h8p5bm	289	28	-	-	HYPH
cord-003130-p2h8p5bm	289	29	borne	bear	VBN
cord-003130-p2h8p5bm	289	30	encephalitis	encephalitis	NN
cord-003130-p2h8p5bm	289	31	Epidemiology	epidemiology	NN
cord-003130-p2h8p5bm	289	32	and	and	CC
cord-003130-p2h8p5bm	289	33	distribution	distribution	NN
cord-003130-p2h8p5bm	289	34	of	of	IN
cord-003130-p2h8p5bm	289	35	tick	tick	NN
cord-003130-p2h8p5bm	289	36	-	-	HYPH
cord-003130-p2h8p5bm	289	37	borne	bear	VBN
cord-003130-p2h8p5bm	289	38	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	289	39	Tick	tick	NN
cord-003130-p2h8p5bm	289	40	-	-	HYPH
cord-003130-p2h8p5bm	289	41	borne	bear	VBN
cord-003130-p2h8p5bm	289	42	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	289	43	2010	2010	CD
cord-003130-p2h8p5bm	289	44	:	:	:
cord-003130-p2h8p5bm	289	45	Epidemiology	epidemiology	NN
cord-003130-p2h8p5bm	289	46	,	,	,
cord-003130-p2h8p5bm	289	47	risk	risk	NN
cord-003130-p2h8p5bm	289	48	areas	area	NNS
cord-003130-p2h8p5bm	289	49	,	,	,
cord-003130-p2h8p5bm	289	50	and	and	CC
cord-003130-p2h8p5bm	289	51	virus	virus	NN
cord-003130-p2h8p5bm	289	52	strains	strain	NNS
cord-003130-p2h8p5bm	289	53	in	in	IN
cord-003130-p2h8p5bm	289	54	europe	europe	NNP
cord-003130-p2h8p5bm	289	55	and	and	CC
cord-003130-p2h8p5bm	289	56	asia	asia	NNP
cord-003130-p2h8p5bm	289	57	-	-	:
cord-003130-p2h8p5bm	289	58	an	an	DT
cord-003130-p2h8p5bm	289	59	overview	overview	NN
cord-003130-p2h8p5bm	289	60	.	.	.
cord-003130-p2h8p5bm	290	1	Ticks	tick	NNS
cord-003130-p2h8p5bm	290	2	Tick	tick	VBP
cord-003130-p2h8p5bm	290	3	Borne	Borne	NNP
cord-003130-p2h8p5bm	290	4	Dis	dis	NN
cord-003130-p2h8p5bm	290	5	Distribution	distribution	NN
cord-003130-p2h8p5bm	290	6	of	of	IN
cord-003130-p2h8p5bm	290	7	ixodes	ixodes	NNP
cord-003130-p2h8p5bm	290	8	ricinus	ricinus	NNP
cord-003130-p2h8p5bm	290	9	ticks	tick	NNS
cord-003130-p2h8p5bm	290	10	and	and	CC
cord-003130-p2h8p5bm	290	11	prevalence	prevalence	NN
cord-003130-p2h8p5bm	290	12	of	of	IN
cord-003130-p2h8p5bm	290	13	tick	tick	NN
cord-003130-p2h8p5bm	290	14	-	-	HYPH
cord-003130-p2h8p5bm	290	15	borne	bear	VBN
cord-003130-p2h8p5bm	290	16	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	290	17	virus	virus	NN
cord-003130-p2h8p5bm	290	18	among	among	IN
cord-003130-p2h8p5bm	290	19	questing	quest	VBG
cord-003130-p2h8p5bm	290	20	ticks	tick	NNS
cord-003130-p2h8p5bm	290	21	in	in	IN
cord-003130-p2h8p5bm	290	22	the	the	DT
cord-003130-p2h8p5bm	290	23	arctic	arctic	NNP
cord-003130-p2h8p5bm	290	24	circle	circle	NN
cord-003130-p2h8p5bm	290	25	region	region	NN
cord-003130-p2h8p5bm	290	26	of	of	IN
cord-003130-p2h8p5bm	290	27	northern	northern	NNP
cord-003130-p2h8p5bm	290	28	norway	norway	NNP
cord-003130-p2h8p5bm	290	29	Persistent	Persistent	NNP
cord-003130-p2h8p5bm	290	30	viremia	viremia	NN
cord-003130-p2h8p5bm	290	31	and	and	CC
cord-003130-p2h8p5bm	290	32	urine	urine	NN
cord-003130-p2h8p5bm	290	33	shedding	shedding	NN
cord-003130-p2h8p5bm	290	34	of	of	IN
cord-003130-p2h8p5bm	290	35	tick	tick	NN
cord-003130-p2h8p5bm	290	36	-	-	HYPH
cord-003130-p2h8p5bm	290	37	borne	bear	VBN
cord-003130-p2h8p5bm	290	38	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	290	39	virus	virus	NN
cord-003130-p2h8p5bm	290	40	in	in	IN
cord-003130-p2h8p5bm	290	41	an	an	DT
cord-003130-p2h8p5bm	290	42	infected	infected	JJ
cord-003130-p2h8p5bm	290	43	immunosuppressed	immunosuppressed	JJ
cord-003130-p2h8p5bm	290	44	patient	patient	NN
cord-003130-p2h8p5bm	290	45	from	from	IN
cord-003130-p2h8p5bm	290	46	a	a	DT
cord-003130-p2h8p5bm	290	47	new	new	JJ
cord-003130-p2h8p5bm	290	48	epidemic	epidemic	NN
cord-003130-p2h8p5bm	290	49	cluster	cluster	NN
cord-003130-p2h8p5bm	290	50	in	in	IN
cord-003130-p2h8p5bm	290	51	north	north	JJ
cord-003130-p2h8p5bm	290	52	-	-	HYPH
cord-003130-p2h8p5bm	290	53	eastern	eastern	JJ
cord-003130-p2h8p5bm	290	54	italy	italy	NNP
cord-003130-p2h8p5bm	291	1	Why	why	WRB
cord-003130-p2h8p5bm	291	2	is	be	VBZ
cord-003130-p2h8p5bm	291	3	tick	tick	VB
cord-003130-p2h8p5bm	291	4	-	-	HYPH
cord-003130-p2h8p5bm	291	5	borne	bear	VBN
cord-003130-p2h8p5bm	291	6	encephalitis	encephalitis	RB
cord-003130-p2h8p5bm	291	7	increasing	increase	VBG
cord-003130-p2h8p5bm	291	8	?	?	.
cord-003130-p2h8p5bm	292	1	A	a	DT
cord-003130-p2h8p5bm	292	2	review	review	NN
cord-003130-p2h8p5bm	292	3	of	of	IN
cord-003130-p2h8p5bm	292	4	the	the	DT
cord-003130-p2h8p5bm	292	5	key	key	JJ
cord-003130-p2h8p5bm	292	6	factors	factor	NNS
cord-003130-p2h8p5bm	292	7	causing	cause	VBG
cord-003130-p2h8p5bm	292	8	the	the	DT
cord-003130-p2h8p5bm	292	9	increasing	increase	VBG
cord-003130-p2h8p5bm	292	10	incidence	incidence	NN
cord-003130-p2h8p5bm	292	11	of	of	IN
cord-003130-p2h8p5bm	292	12	human	human	JJ
cord-003130-p2h8p5bm	292	13	tbe	tbe	NN
cord-003130-p2h8p5bm	292	14	in	in	IN
cord-003130-p2h8p5bm	292	15	sweden	sweden	NNP
cord-003130-p2h8p5bm	293	1	A	a	DT
cord-003130-p2h8p5bm	293	2	new	new	JJ
cord-003130-p2h8p5bm	293	3	hot	hot	JJ
cord-003130-p2h8p5bm	293	4	spot	spot	NN
cord-003130-p2h8p5bm	293	5	for	for	IN
cord-003130-p2h8p5bm	293	6	tick	tick	NN
cord-003130-p2h8p5bm	293	7	-	-	HYPH
cord-003130-p2h8p5bm	293	8	borne	bear	VBN
cord-003130-p2h8p5bm	293	9	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	293	10	(	(	-LRB-
cord-003130-p2h8p5bm	293	11	tbe	tbe	NN
cord-003130-p2h8p5bm	293	12	)	)	-RRB-
cord-003130-p2h8p5bm	293	13	:	:	:
cord-003130-p2h8p5bm	294	1	A	a	DT
cord-003130-p2h8p5bm	294	2	marked	marked	JJ
cord-003130-p2h8p5bm	294	3	increase	increase	NN
cord-003130-p2h8p5bm	294	4	of	of	IN
cord-003130-p2h8p5bm	294	5	tbe	tbe	NN
cord-003130-p2h8p5bm	294	6	cases	case	NNS
cord-003130-p2h8p5bm	294	7	in	in	IN
cord-003130-p2h8p5bm	294	8	france	france	NNP
cord-003130-p2h8p5bm	294	9	in	in	IN
cord-003130-p2h8p5bm	294	10	2016	2016	CD
cord-003130-p2h8p5bm	295	1	To	to	TO
cord-003130-p2h8p5bm	295	2	what	what	WDT
cord-003130-p2h8p5bm	295	3	extent	extent	NN
cord-003130-p2h8p5bm	295	4	has	have	VBZ
cord-003130-p2h8p5bm	295	5	climate	climate	NN
cord-003130-p2h8p5bm	295	6	change	change	NN
cord-003130-p2h8p5bm	295	7	contributed	contribute	VBD
cord-003130-p2h8p5bm	295	8	to	to	IN
cord-003130-p2h8p5bm	295	9	the	the	DT
cord-003130-p2h8p5bm	295	10	recent	recent	JJ
cord-003130-p2h8p5bm	295	11	epidemiology	epidemiology	NN
cord-003130-p2h8p5bm	295	12	of	of	IN
cord-003130-p2h8p5bm	295	13	tick	tick	NN
cord-003130-p2h8p5bm	295	14	-	-	HYPH
cord-003130-p2h8p5bm	295	15	borne	bear	VBN
cord-003130-p2h8p5bm	295	16	diseases	disease	NNS
cord-003130-p2h8p5bm	295	17	?	?	.
cord-003130-p2h8p5bm	296	1	Socio	socio	JJ
cord-003130-p2h8p5bm	296	2	-	-	HYPH
cord-003130-p2h8p5bm	296	3	economic	economic	JJ
cord-003130-p2h8p5bm	296	4	factors	factor	NNS
cord-003130-p2h8p5bm	296	5	in	in	IN
cord-003130-p2h8p5bm	296	6	the	the	DT
cord-003130-p2h8p5bm	296	7	differential	differential	JJ
cord-003130-p2h8p5bm	296	8	upsurge	upsurge	NN
cord-003130-p2h8p5bm	296	9	of	of	IN
cord-003130-p2h8p5bm	296	10	tick	tick	NN
cord-003130-p2h8p5bm	296	11	-	-	HYPH
cord-003130-p2h8p5bm	296	12	borne	bear	VBN
cord-003130-p2h8p5bm	296	13	encephalitis	encephalitis	RB
cord-003130-p2h8p5bm	296	14	in	in	IN
cord-003130-p2h8p5bm	296	15	central	central	JJ
cord-003130-p2h8p5bm	296	16	and	and	CC
cord-003130-p2h8p5bm	296	17	eastern	eastern	NNP
cord-003130-p2h8p5bm	296	18	europe	europe	NNP
cord-003130-p2h8p5bm	296	19	Survival	Survival	NNP
cord-003130-p2h8p5bm	296	20	strategy	strategy	NN
cord-003130-p2h8p5bm	296	21	of	of	IN
cord-003130-p2h8p5bm	296	22	tick	tick	NN
cord-003130-p2h8p5bm	296	23	-	-	HYPH
cord-003130-p2h8p5bm	296	24	borne	bear	VBN
cord-003130-p2h8p5bm	296	25	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	296	26	virus	virus	NN
cord-003130-p2h8p5bm	296	27	:	:	:
cord-003130-p2h8p5bm	296	28	Cellular	cellular	JJ
cord-003130-p2h8p5bm	296	29	basis	basis	NN
cord-003130-p2h8p5bm	296	30	and	and	CC
cord-003130-p2h8p5bm	296	31	environmental	environmental	JJ
cord-003130-p2h8p5bm	296	32	determinants	determinant	NNS
cord-003130-p2h8p5bm	297	1	Tick	tick	VB
cord-003130-p2h8p5bm	297	2	-	-	HYPH
cord-003130-p2h8p5bm	297	3	borne	bear	VBN
cord-003130-p2h8p5bm	297	4	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	297	5	virus	virus	NN
cord-003130-p2h8p5bm	297	6	-	-	:
cord-003130-p2h8p5bm	297	7	A	a	DT
cord-003130-p2h8p5bm	297	8	review	review	NN
cord-003130-p2h8p5bm	297	9	of	of	IN
cord-003130-p2h8p5bm	297	10	an	an	DT
cord-003130-p2h8p5bm	297	11	emerging	emerge	VBG
cord-003130-p2h8p5bm	297	12	zoonosis	zoonosis	NN
cord-003130-p2h8p5bm	298	1	An	an	DT
cord-003130-p2h8p5bm	298	2	outbreak	outbreak	NN
cord-003130-p2h8p5bm	298	3	of	of	IN
cord-003130-p2h8p5bm	298	4	tick	tick	NN
cord-003130-p2h8p5bm	298	5	-	-	HYPH
cord-003130-p2h8p5bm	298	6	borne	bear	VBN
cord-003130-p2h8p5bm	298	7	encephalitis	encephalitis	RB
cord-003130-p2h8p5bm	298	8	associated	associate	VBN
cord-003130-p2h8p5bm	298	9	with	with	IN
cord-003130-p2h8p5bm	298	10	raw	raw	JJ
cord-003130-p2h8p5bm	298	11	goat	goat	NN
cord-003130-p2h8p5bm	298	12	milk	milk	NN
cord-003130-p2h8p5bm	298	13	and	and	CC
cord-003130-p2h8p5bm	298	14	cheese	cheese	NN
cord-003130-p2h8p5bm	298	15	consumption	consumption	NN
cord-003130-p2h8p5bm	298	16	,	,	,
cord-003130-p2h8p5bm	298	17	croatia	croatia	NNP
cord-003130-p2h8p5bm	298	18	Avsic	Avsic	NNP
cord-003130-p2h8p5bm	298	19	-	-	HYPH
cord-003130-p2h8p5bm	298	20	Zupanc	Zupanc	NNP
cord-003130-p2h8p5bm	298	21	,	,	,
cord-003130-p2h8p5bm	298	22	T.	T.	NNP
cord-003130-p2h8p5bm	298	23	Tick	tick	NN
cord-003130-p2h8p5bm	298	24	-	-	HYPH
cord-003130-p2h8p5bm	298	25	borne	bear	VBN
cord-003130-p2h8p5bm	298	26	encephalitis	encephalitis	RB
cord-003130-p2h8p5bm	298	27	associated	associate	VBN
cord-003130-p2h8p5bm	298	28	with	with	IN
cord-003130-p2h8p5bm	298	29	consumption	consumption	NN
cord-003130-p2h8p5bm	298	30	of	of	IN
cord-003130-p2h8p5bm	298	31	raw	raw	JJ
cord-003130-p2h8p5bm	298	32	goat	goat	NN
cord-003130-p2h8p5bm	298	33	milk	milk	NN
cord-003130-p2h8p5bm	298	34	,	,	,
cord-003130-p2h8p5bm	298	35	slovenia	slovenia	NNP
cord-003130-p2h8p5bm	298	36	A	a	DT
cord-003130-p2h8p5bm	298	37	cluster	cluster	NN
cord-003130-p2h8p5bm	298	38	of	of	IN
cord-003130-p2h8p5bm	298	39	fatal	fatal	JJ
cord-003130-p2h8p5bm	298	40	tick	tick	NN
cord-003130-p2h8p5bm	298	41	-	-	HYPH
cord-003130-p2h8p5bm	298	42	borne	bear	VBN
cord-003130-p2h8p5bm	298	43	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	298	44	virus	virus	NN
cord-003130-p2h8p5bm	298	45	infection	infection	NN
cord-003130-p2h8p5bm	298	46	in	in	IN
cord-003130-p2h8p5bm	298	47	organ	organ	NN
cord-003130-p2h8p5bm	298	48	transplant	transplant	NN
cord-003130-p2h8p5bm	298	49	setting	set	VBG
cord-003130-p2h8p5bm	298	50	Tick	tick	VB
cord-003130-p2h8p5bm	298	51	-	-	HYPH
cord-003130-p2h8p5bm	298	52	borne	bear	VBN
cord-003130-p2h8p5bm	298	53	flaviviruses	flavivirus	NNS
cord-003130-p2h8p5bm	298	54	:	:	:
cord-003130-p2h8p5bm	299	1	Dissecting	dissect	VBG
cord-003130-p2h8p5bm	299	2	host	host	NN
cord-003130-p2h8p5bm	299	3	immune	immune	JJ
cord-003130-p2h8p5bm	299	4	responses	response	NNS
cord-003130-p2h8p5bm	299	5	and	and	CC
cord-003130-p2h8p5bm	299	6	virus	virus	NN
cord-003130-p2h8p5bm	299	7	countermeasures	countermeasure	NNS
cord-003130-p2h8p5bm	300	1	Langerhans	Langerhans	NNP
cord-003130-p2h8p5bm	300	2	cells	cell	NNS
cord-003130-p2h8p5bm	300	3	migrate	migrate	VBP
cord-003130-p2h8p5bm	300	4	to	to	IN
cord-003130-p2h8p5bm	300	5	local	local	JJ
cord-003130-p2h8p5bm	300	6	lymph	lymph	NN
cord-003130-p2h8p5bm	300	7	nodes	node	NNS
cord-003130-p2h8p5bm	300	8	following	follow	VBG
cord-003130-p2h8p5bm	300	9	cutaneous	cutaneous	JJ
cord-003130-p2h8p5bm	300	10	infection	infection	NN
cord-003130-p2h8p5bm	300	11	with	with	IN
cord-003130-p2h8p5bm	300	12	an	an	DT
cord-003130-p2h8p5bm	300	13	arbovirus	arbovirus	NN
cord-003130-p2h8p5bm	301	1	The	the	DT
cord-003130-p2h8p5bm	301	2	Togaviridae	Togaviridae	NNP
cord-003130-p2h8p5bm	301	3	and	and	CC
cord-003130-p2h8p5bm	301	4	Flaviviridae	Flaviviridae	NNP
cord-003130-p2h8p5bm	301	5	Tick	Tick	NNP
cord-003130-p2h8p5bm	301	6	-	-	HYPH
cord-003130-p2h8p5bm	301	7	borne	bear	VBN
cord-003130-p2h8p5bm	301	8	encephalitis	encephalitis	RB
cord-003130-p2h8p5bm	301	9	:	:	:
cord-003130-p2h8p5bm	301	10	Pathogenesis	pathogenesis	NN
cord-003130-p2h8p5bm	301	11	and	and	CC
cord-003130-p2h8p5bm	301	12	clinical	clinical	JJ
cord-003130-p2h8p5bm	301	13	implications	implication	NNS
cord-003130-p2h8p5bm	302	1	The	the	DT
cord-003130-p2h8p5bm	302	2	clinical	clinical	JJ
cord-003130-p2h8p5bm	302	3	and	and	CC
cord-003130-p2h8p5bm	302	4	epidemiological	epidemiological	JJ
cord-003130-p2h8p5bm	302	5	profile	profile	NN
cord-003130-p2h8p5bm	302	6	of	of	IN
cord-003130-p2h8p5bm	302	7	tick	tick	NN
cord-003130-p2h8p5bm	302	8	-	-	HYPH
cord-003130-p2h8p5bm	302	9	borne	bear	VBN
cord-003130-p2h8p5bm	302	10	encephalitis	encephalitis	RB
cord-003130-p2h8p5bm	302	11	in	in	IN
cord-003130-p2h8p5bm	302	12	southern	southern	JJ
cord-003130-p2h8p5bm	302	13	germany	germany	NNP
cord-003130-p2h8p5bm	302	14	1994	1994	CD
cord-003130-p2h8p5bm	302	15	-	-	SYM
cord-003130-p2h8p5bm	302	16	1998	1998	CD
cord-003130-p2h8p5bm	302	17	:	:	:
cord-003130-p2h8p5bm	303	1	A	a	DT
cord-003130-p2h8p5bm	303	2	prospective	prospective	JJ
cord-003130-p2h8p5bm	303	3	study	study	NN
cord-003130-p2h8p5bm	303	4	of	of	IN
cord-003130-p2h8p5bm	303	5	656	656	CD
cord-003130-p2h8p5bm	303	6	patients	patient	NNS
cord-003130-p2h8p5bm	303	7	Tickborne	Tickborne	NNP
cord-003130-p2h8p5bm	303	8	encephalitis	encephalitis	RB
cord-003130-p2h8p5bm	303	9	in	in	IN
cord-003130-p2h8p5bm	303	10	an	an	DT
cord-003130-p2h8p5bm	303	11	area	area	NN
cord-003130-p2h8p5bm	303	12	of	of	IN
cord-003130-p2h8p5bm	303	13	high	high	JJ
cord-003130-p2h8p5bm	303	14	endemicity	endemicity	NN
cord-003130-p2h8p5bm	303	15	in	in	IN
cord-003130-p2h8p5bm	303	16	lithuania	lithuania	NNP
cord-003130-p2h8p5bm	303	17	:	:	:
cord-003130-p2h8p5bm	303	18	Disease	Disease	NNP
cord-003130-p2h8p5bm	303	19	severity	severity	NN
cord-003130-p2h8p5bm	303	20	and	and	CC
cord-003130-p2h8p5bm	303	21	long	long	JJ
cord-003130-p2h8p5bm	303	22	-	-	HYPH
cord-003130-p2h8p5bm	303	23	term	term	NN
cord-003130-p2h8p5bm	303	24	prognosis	prognosis	NN
cord-003130-p2h8p5bm	303	25	Human	human	JJ
cord-003130-p2h8p5bm	303	26	tick	tick	NN
cord-003130-p2h8p5bm	303	27	-	-	HYPH
cord-003130-p2h8p5bm	303	28	borne	bear	VBN
cord-003130-p2h8p5bm	303	29	encephalitis	encephalitis	NN
cord-003130-p2h8p5bm	303	30	and	and	CC
cord-003130-p2h8p5bm	303	31	characterization	characterization	NN
cord-003130-p2h8p5bm	303	32	of	of	IN
cord-003130-p2h8p5bm	303	33	virus	virus	NN
cord-003130-p2h8p5bm	303	34	from	from	IN
cord-003130-p2h8p5bm	303	35	biting	bite	VBG
cord-003130-p2h8p5bm	303	36	tick	tick	NN
cord-003130-p2h8p5bm	303	37	Tick	Tick	NNP
cord-003130-p2h8p5bm	303	38	-	-	HYPH
cord-003130-p2h8p5bm	303	39	borne	bear	VBN
cord-003130-p2h8p5bm	303	40	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	303	41	virus	virus	NN
cord-003130-p2h8p5bm	303	42	and	and	CC
cord-003130-p2h8p5bm	303	43	the	the	DT
cord-003130-p2h8p5bm	303	44	immune	immune	JJ
cord-003130-p2h8p5bm	303	45	response	response	NN
cord-003130-p2h8p5bm	303	46	of	of	IN
cord-003130-p2h8p5bm	303	47	the	the	DT
cord-003130-p2h8p5bm	303	48	mammalian	mammalian	JJ
cord-003130-p2h8p5bm	303	49	host	host	NN
cord-003130-p2h8p5bm	303	50	Neurological	neurological	JJ
cord-003130-p2h8p5bm	303	51	complications	complication	NNS
cord-003130-p2h8p5bm	303	52	of	of	IN
cord-003130-p2h8p5bm	303	53	tick	tick	NN
cord-003130-p2h8p5bm	303	54	borne	bear	VBN
cord-003130-p2h8p5bm	303	55	encephalitis	encephalitis	RB
cord-003130-p2h8p5bm	303	56	:	:	:
cord-003130-p2h8p5bm	304	1	The	the	DT
cord-003130-p2h8p5bm	304	2	experience	experience	NN
cord-003130-p2h8p5bm	304	3	of	of	IN
cord-003130-p2h8p5bm	304	4	89	89	CD
cord-003130-p2h8p5bm	304	5	patients	patient	NNS
cord-003130-p2h8p5bm	304	6	studied	study	VBN
cord-003130-p2h8p5bm	304	7	and	and	CC
cord-003130-p2h8p5bm	304	8	literature	literature	NN
cord-003130-p2h8p5bm	304	9	review	review	NN
cord-003130-p2h8p5bm	304	10	Tick	tick	NN
cord-003130-p2h8p5bm	304	11	-	-	HYPH
cord-003130-p2h8p5bm	304	12	borne	bear	VBN
cord-003130-p2h8p5bm	304	13	encephalitis	encephalitis	NN
cord-003130-p2h8p5bm	304	14	-	-	HYPH
cord-003130-p2h8p5bm	304	15	Pathogenesis	Pathogenesis	NNP
cord-003130-p2h8p5bm	304	16	,	,	,
cord-003130-p2h8p5bm	304	17	clinical	clinical	JJ
cord-003130-p2h8p5bm	304	18	course	course	NN
cord-003130-p2h8p5bm	304	19	and	and	CC
cord-003130-p2h8p5bm	304	20	long	long	JJ
cord-003130-p2h8p5bm	304	21	-	-	HYPH
cord-003130-p2h8p5bm	304	22	term	term	NN
cord-003130-p2h8p5bm	304	23	follow	follow	NN
cord-003130-p2h8p5bm	304	24	-	-	HYPH
cord-003130-p2h8p5bm	304	25	up	up	NN
cord-003130-p2h8p5bm	304	26	.	.	.
cord-003130-p2h8p5bm	305	1	Vaccine	Vaccine	NNP
cord-003130-p2h8p5bm	305	2	Tick	tick	NN
cord-003130-p2h8p5bm	305	3	-	-	HYPH
cord-003130-p2h8p5bm	305	4	borne	bear	VBN
cord-003130-p2h8p5bm	305	5	viruses	virus	NNS
cord-003130-p2h8p5bm	305	6	:	:	:
cord-003130-p2h8p5bm	305	7	A	a	DT
cord-003130-p2h8p5bm	305	8	review	review	NN
cord-003130-p2h8p5bm	305	9	from	from	IN
cord-003130-p2h8p5bm	305	10	the	the	DT
cord-003130-p2h8p5bm	305	11	perspective	perspective	NN
cord-003130-p2h8p5bm	305	12	of	of	IN
cord-003130-p2h8p5bm	305	13	therapeutic	therapeutic	JJ
cord-003130-p2h8p5bm	305	14	approaches	approach	NNS
cord-003130-p2h8p5bm	305	15	Experimental	experimental	JJ
cord-003130-p2h8p5bm	305	16	milk	milk	NN
cord-003130-p2h8p5bm	305	17	-	-	HYPH
cord-003130-p2h8p5bm	305	18	borne	bear	VBN
cord-003130-p2h8p5bm	305	19	transmission	transmission	NN
cord-003130-p2h8p5bm	305	20	of	of	IN
cord-003130-p2h8p5bm	305	21	powassan	powassan	NNP
cord-003130-p2h8p5bm	305	22	virus	virus	NN
cord-003130-p2h8p5bm	305	23	in	in	IN
cord-003130-p2h8p5bm	305	24	the	the	DT
cord-003130-p2h8p5bm	305	25	goat	goat	NN
cord-003130-p2h8p5bm	305	26	Tick	Tick	NNP
cord-003130-p2h8p5bm	305	27	saliva	saliva	NN
cord-003130-p2h8p5bm	305	28	enhances	enhance	VBZ
cord-003130-p2h8p5bm	305	29	powassan	powassan	NNP
cord-003130-p2h8p5bm	305	30	virus	virus	NN
cord-003130-p2h8p5bm	305	31	transmission	transmission	NN
cord-003130-p2h8p5bm	305	32	to	to	IN
cord-003130-p2h8p5bm	305	33	the	the	DT
cord-003130-p2h8p5bm	305	34	host	host	NN
cord-003130-p2h8p5bm	305	35	,	,	,
cord-003130-p2h8p5bm	305	36	influencing	influence	VBG
cord-003130-p2h8p5bm	305	37	its	-PRON-	PRP$
cord-003130-p2h8p5bm	305	38	dissemination	dissemination	NN
cord-003130-p2h8p5bm	305	39	and	and	CC
cord-003130-p2h8p5bm	305	40	the	the	DT
cord-003130-p2h8p5bm	305	41	course	course	NN
cord-003130-p2h8p5bm	305	42	of	of	IN
cord-003130-p2h8p5bm	305	43	disease	disease	NN
cord-003130-p2h8p5bm	305	44	Immune	immune	JJ
cord-003130-p2h8p5bm	305	45	cell	cell	NN
cord-003130-p2h8p5bm	305	46	targets	target	NNS
cord-003130-p2h8p5bm	305	47	of	of	IN
cord-003130-p2h8p5bm	305	48	infection	infection	NN
cord-003130-p2h8p5bm	305	49	at	at	IN
cord-003130-p2h8p5bm	305	50	the	the	DT
cord-003130-p2h8p5bm	305	51	tick	tick	NN
cord-003130-p2h8p5bm	305	52	-	-	HYPH
cord-003130-p2h8p5bm	305	53	skin	skin	NN
cord-003130-p2h8p5bm	305	54	interface	interface	NN
cord-003130-p2h8p5bm	305	55	during	during	IN
cord-003130-p2h8p5bm	305	56	powassan	powassan	NNP
cord-003130-p2h8p5bm	305	57	virus	virus	NN
cord-003130-p2h8p5bm	305	58	transmission	transmission	NN
cord-003130-p2h8p5bm	305	59	Spinal	spinal	JJ
cord-003130-p2h8p5bm	305	60	cord	cord	NN
cord-003130-p2h8p5bm	305	61	ventral	ventral	JJ
cord-003130-p2h8p5bm	305	62	horns	horn	NNS
cord-003130-p2h8p5bm	305	63	and	and	CC
cord-003130-p2h8p5bm	305	64	lymphoid	lymphoid	JJ
cord-003130-p2h8p5bm	305	65	organ	organ	NN
cord-003130-p2h8p5bm	305	66	involvement	involvement	NN
cord-003130-p2h8p5bm	305	67	in	in	IN
cord-003130-p2h8p5bm	305	68	powassan	powassan	NNP
cord-003130-p2h8p5bm	305	69	virus	virus	NN
cord-003130-p2h8p5bm	305	70	infection	infection	NN
cord-003130-p2h8p5bm	305	71	in	in	IN
cord-003130-p2h8p5bm	305	72	a	a	DT
cord-003130-p2h8p5bm	305	73	mouse	mouse	NN
cord-003130-p2h8p5bm	305	74	model	model	NN
cord-003130-p2h8p5bm	305	75	Powassan	Powassan	NNP
cord-003130-p2h8p5bm	305	76	encephalitis	encephalitis	RB
cord-003130-p2h8p5bm	305	77	:	:	:
cord-003130-p2h8p5bm	305	78	A	a	DT
cord-003130-p2h8p5bm	305	79	case	case	NN
cord-003130-p2h8p5bm	305	80	report	report	NN
cord-003130-p2h8p5bm	305	81	with	with	IN
cord-003130-p2h8p5bm	305	82	neuropathology	neuropathology	NN
cord-003130-p2h8p5bm	305	83	and	and	CC
cord-003130-p2h8p5bm	305	84	literature	literature	NN
cord-003130-p2h8p5bm	305	85	review	review	NN
cord-003130-p2h8p5bm	305	86	Update	update	NN
cord-003130-p2h8p5bm	305	87	on	on	IN
cord-003130-p2h8p5bm	305	88	powassan	powassan	NNP
cord-003130-p2h8p5bm	305	89	virus	virus	NN
cord-003130-p2h8p5bm	305	90	:	:	:
cord-003130-p2h8p5bm	305	91	Emergence	emergence	NN
cord-003130-p2h8p5bm	305	92	of	of	IN
cord-003130-p2h8p5bm	305	93	a	a	DT
cord-003130-p2h8p5bm	305	94	north	north	JJ
cord-003130-p2h8p5bm	305	95	american	american	JJ
cord-003130-p2h8p5bm	305	96	tick	tick	NN
cord-003130-p2h8p5bm	305	97	-	-	HYPH
cord-003130-p2h8p5bm	305	98	borne	bear	VBN
cord-003130-p2h8p5bm	305	99	flavivirus	flavivirus	NNP
cord-003130-p2h8p5bm	305	100	Powassan	Powassan	NNP
cord-003130-p2h8p5bm	305	101	virus	virus	NN
cord-003130-p2h8p5bm	305	102	:	:	:
cord-003130-p2h8p5bm	305	103	An	an	DT
cord-003130-p2h8p5bm	305	104	emerging	emerge	VBG
cord-003130-p2h8p5bm	305	105	arbovirus	arbovirus	NN
cord-003130-p2h8p5bm	305	106	of	of	IN
cord-003130-p2h8p5bm	305	107	public	public	JJ
cord-003130-p2h8p5bm	305	108	health	health	NN
cord-003130-p2h8p5bm	305	109	concern	concern	NN
cord-003130-p2h8p5bm	305	110	in	in	IN
cord-003130-p2h8p5bm	305	111	north	north	NNP
cord-003130-p2h8p5bm	305	112	america	america	NNP
cord-003130-p2h8p5bm	305	113	.	.	.
cord-003130-p2h8p5bm	306	1	Vector	Vector	NNP
cord-003130-p2h8p5bm	306	2	Borne	Borne	NNP
cord-003130-p2h8p5bm	306	3	Zoonotic	Zoonotic	NNP
cord-003130-p2h8p5bm	306	4	Dis	Dis	NNP
cord-003130-p2h8p5bm	306	5	Louping	Louping	NNP
cord-003130-p2h8p5bm	306	6	ill	ill	JJ
cord-003130-p2h8p5bm	306	7	virus	virus	NN
cord-003130-p2h8p5bm	306	8	in	in	IN
cord-003130-p2h8p5bm	306	9	the	the	DT
cord-003130-p2h8p5bm	306	10	UK	UK	NNP
cord-003130-p2h8p5bm	306	11	:	:	:
cord-003130-p2h8p5bm	307	1	A	a	DT
cord-003130-p2h8p5bm	307	2	review	review	NN
cord-003130-p2h8p5bm	307	3	of	of	IN
cord-003130-p2h8p5bm	307	4	the	the	DT
cord-003130-p2h8p5bm	307	5	hosts	host	NNS
cord-003130-p2h8p5bm	307	6	,	,	,
cord-003130-p2h8p5bm	307	7	transmission	transmission	NN
cord-003130-p2h8p5bm	307	8	and	and	CC
cord-003130-p2h8p5bm	307	9	ecological	ecological	JJ
cord-003130-p2h8p5bm	307	10	consequences	consequence	NNS
cord-003130-p2h8p5bm	307	11	of	of	IN
cord-003130-p2h8p5bm	307	12	control	control	NN
cord-003130-p2h8p5bm	308	1	Louping	loupe	VBG
cord-003130-p2h8p5bm	308	2	ill	ill	JJ
cord-003130-p2h8p5bm	308	3	virus	virus	NN
cord-003130-p2h8p5bm	308	4	:	:	:
cord-003130-p2h8p5bm	309	1	An	an	DT
cord-003130-p2h8p5bm	309	2	endemic	endemic	JJ
cord-003130-p2h8p5bm	309	3	tick	tick	NN
cord-003130-p2h8p5bm	309	4	-	-	HYPH
cord-003130-p2h8p5bm	309	5	borne	bear	VBN
cord-003130-p2h8p5bm	309	6	disease	disease	NN
cord-003130-p2h8p5bm	309	7	of	of	IN
cord-003130-p2h8p5bm	309	8	great	great	NNP
cord-003130-p2h8p5bm	309	9	britain	britain	NNP
cord-003130-p2h8p5bm	309	10	Louping	Louping	NNP
cord-003130-p2h8p5bm	309	11	ill	ill	RB
cord-003130-p2h8p5bm	309	12	in	in	IN
cord-003130-p2h8p5bm	309	13	man	man	NN
cord-003130-p2h8p5bm	309	14	Louping	Louping	NNP
cord-003130-p2h8p5bm	309	15	-	-	HYPH
cord-003130-p2h8p5bm	309	16	ill	ill	JJ
cord-003130-p2h8p5bm	309	17	meningo	meningo	NN
cord-003130-p2h8p5bm	309	18	-	-	HYPH
cord-003130-p2h8p5bm	309	19	encephalitis	encephalitis	RB
cord-003130-p2h8p5bm	309	20	;	;	:
cord-003130-p2h8p5bm	309	21	a	a	DT
cord-003130-p2h8p5bm	309	22	further	further	JJ
cord-003130-p2h8p5bm	309	23	case	case	NN
cord-003130-p2h8p5bm	309	24	and	and	CC
cord-003130-p2h8p5bm	309	25	a	a	DT
cord-003130-p2h8p5bm	309	26	serological	serological	JJ
cord-003130-p2h8p5bm	309	27	survey	survey	NN
cord-003130-p2h8p5bm	309	28	Occupational	occupational	JJ
cord-003130-p2h8p5bm	309	29	infections	infection	NNS
cord-003130-p2h8p5bm	309	30	in	in	IN
cord-003130-p2h8p5bm	309	31	the	the	DT
cord-003130-p2h8p5bm	309	32	edinburgh	edinburgh	NNP
cord-003130-p2h8p5bm	309	33	abattoir	abattoir	NNP
cord-003130-p2h8p5bm	309	34	Laboratory	Laboratory	NNP
cord-003130-p2h8p5bm	309	35	infections	infection	NNS
cord-003130-p2h8p5bm	309	36	with	with	IN
cord-003130-p2h8p5bm	309	37	louping	loupe	VBG
cord-003130-p2h8p5bm	309	38	-	-	HYPH
cord-003130-p2h8p5bm	309	39	ill	ill	JJ
cord-003130-p2h8p5bm	309	40	virus	virus	NN
cord-003130-p2h8p5bm	310	1	Louping	loupe	VBG
cord-003130-p2h8p5bm	310	2	ill	ill	RB
cord-003130-p2h8p5bm	310	3	in	in	IN
cord-003130-p2h8p5bm	310	4	man	man	NN
cord-003130-p2h8p5bm	310	5	:	:	:
cord-003130-p2h8p5bm	311	1	A	a	DT
cord-003130-p2h8p5bm	311	2	forgotten	forget	VBN
cord-003130-p2h8p5bm	311	3	disease	disease	NN
cord-003130-p2h8p5bm	311	4	Omsk	Omsk	NNP
cord-003130-p2h8p5bm	311	5	haemorrhagic	haemorrhagic	JJ
cord-003130-p2h8p5bm	311	6	fever	fever	NN
cord-003130-p2h8p5bm	311	7	Kyasanur	Kyasanur	NNP
cord-003130-p2h8p5bm	311	8	forest	forest	NN
cord-003130-p2h8p5bm	311	9	disease	disease	NN
cord-003130-p2h8p5bm	311	10	.	.	.
cord-003130-p2h8p5bm	312	1	VIII	VIII	NNP
cord-003130-p2h8p5bm	312	2	.	.	.
cord-003130-p2h8p5bm	313	1	Isolation	isolation	NN
cord-003130-p2h8p5bm	313	2	of	of	IN
cord-003130-p2h8p5bm	313	3	kyasanur	kyasanur	NNP
cord-003130-p2h8p5bm	313	4	forest	forest	NNP
cord-003130-p2h8p5bm	313	5	disease	disease	NNP
cord-003130-p2h8p5bm	313	6	virus	virus	NN
cord-003130-p2h8p5bm	313	7	from	from	IN
cord-003130-p2h8p5bm	313	8	naturally	naturally	RB
cord-003130-p2h8p5bm	313	9	infected	infect	VBN
cord-003130-p2h8p5bm	313	10	ticks	tick	NNS
cord-003130-p2h8p5bm	313	11	of	of	IN
cord-003130-p2h8p5bm	313	12	the	the	DT
cord-003130-p2h8p5bm	313	13	genus	genus	NN
cord-003130-p2h8p5bm	313	14	haemaphysalis	haemaphysalis	NNP
cord-003130-p2h8p5bm	313	15	Kyasanur	Kyasanur	NNP
cord-003130-p2h8p5bm	313	16	forest	forest	NN
cord-003130-p2h8p5bm	313	17	disease	disease	NN
cord-003130-p2h8p5bm	313	18	Clinical	Clinical	NNP
cord-003130-p2h8p5bm	313	19	,	,	,
cord-003130-p2h8p5bm	313	20	clinicopathologic	clinicopathologic	NNP
cord-003130-p2h8p5bm	313	21	,	,	,
cord-003130-p2h8p5bm	313	22	and	and	CC
cord-003130-p2h8p5bm	313	23	hematologic	hematologic	JJ
cord-003130-p2h8p5bm	313	24	features	feature	NNS
cord-003130-p2h8p5bm	313	25	of	of	IN
cord-003130-p2h8p5bm	313	26	kyasanur	kyasanur	NNP
cord-003130-p2h8p5bm	313	27	forest	forest	NNP
cord-003130-p2h8p5bm	313	28	disease	disease	NN
cord-003130-p2h8p5bm	313	29	Kyasanur	Kyasanur	NNP
cord-003130-p2h8p5bm	313	30	forest	forest	NN
cord-003130-p2h8p5bm	313	31	disease	disease	NN
cord-003130-p2h8p5bm	313	32	:	:	:
cord-003130-p2h8p5bm	314	1	An	an	DT
cord-003130-p2h8p5bm	314	2	epidemiological	epidemiological	JJ
cord-003130-p2h8p5bm	314	3	view	view	NN
cord-003130-p2h8p5bm	314	4	in	in	IN
cord-003130-p2h8p5bm	314	5	India	India	NNP
cord-003130-p2h8p5bm	314	6	Field	Field	NNP
cord-003130-p2h8p5bm	314	7	evaluation	evaluation	NN
cord-003130-p2h8p5bm	314	8	of	of	IN
cord-003130-p2h8p5bm	314	9	formalin	formalin	NN
cord-003130-p2h8p5bm	314	10	inactivated	inactivate	VBN
cord-003130-p2h8p5bm	314	11	kyasanur	kyasanur	NNP
cord-003130-p2h8p5bm	314	12	forest	forest	NNP
cord-003130-p2h8p5bm	314	13	disease	disease	NNP
cord-003130-p2h8p5bm	314	14	virus	virus	NN
cord-003130-p2h8p5bm	314	15	tissue	tissue	NN
cord-003130-p2h8p5bm	314	16	culture	culture	NN
cord-003130-p2h8p5bm	314	17	vaccine	vaccine	NN
cord-003130-p2h8p5bm	314	18	in	in	IN
cord-003130-p2h8p5bm	314	19	three	three	CD
cord-003130-p2h8p5bm	314	20	districts	district	NNS
cord-003130-p2h8p5bm	314	21	of	of	IN
cord-003130-p2h8p5bm	314	22	karnataka	karnataka	NNP
cord-003130-p2h8p5bm	314	23	state	state	NNP
cord-003130-p2h8p5bm	314	24	Coverage	Coverage	NNP
cord-003130-p2h8p5bm	314	25	and	and	CC
cord-003130-p2h8p5bm	314	26	effectiveness	effectiveness	NN
cord-003130-p2h8p5bm	314	27	of	of	IN
cord-003130-p2h8p5bm	314	28	kyasanur	kyasanur	NNP
cord-003130-p2h8p5bm	314	29	forest	forest	NNP
cord-003130-p2h8p5bm	314	30	disease	disease	NNP
cord-003130-p2h8p5bm	314	31	(	(	-LRB-
cord-003130-p2h8p5bm	314	32	KFD	KFD	NNP
cord-003130-p2h8p5bm	314	33	)	)	-RRB-
cord-003130-p2h8p5bm	314	34	vaccine	vaccine	NN
cord-003130-p2h8p5bm	314	35	in	in	IN
cord-003130-p2h8p5bm	314	36	karnataka	karnataka	NNP
cord-003130-p2h8p5bm	314	37	,	,	,
cord-003130-p2h8p5bm	314	38	south	south	NNP
cord-003130-p2h8p5bm	314	39	india	india	NNP
cord-003130-p2h8p5bm	314	40	Flavivirus	Flavivirus	NNP
cord-003130-p2h8p5bm	314	41	RNA	RNA	NNP
cord-003130-p2h8p5bm	314	42	transactions	transaction	NNS
cord-003130-p2h8p5bm	314	43	from	from	IN
cord-003130-p2h8p5bm	314	44	viral	viral	JJ
cord-003130-p2h8p5bm	314	45	entry	entry	NN
cord-003130-p2h8p5bm	314	46	to	to	IN
cord-003130-p2h8p5bm	314	47	genome	genome	NN
cord-003130-p2h8p5bm	314	48	replication	replication	NN
cord-003130-p2h8p5bm	314	49	Insect	insect	NN
cord-003130-p2h8p5bm	314	50	-	-	HYPH
cord-003130-p2h8p5bm	314	51	specific	specific	JJ
cord-003130-p2h8p5bm	314	52	flaviviruses	flavivirus	NNS
cord-003130-p2h8p5bm	314	53	:	:	:
cord-003130-p2h8p5bm	314	54	A	a	DT
cord-003130-p2h8p5bm	314	55	systematic	systematic	JJ
cord-003130-p2h8p5bm	314	56	review	review	NN
cord-003130-p2h8p5bm	314	57	of	of	IN
cord-003130-p2h8p5bm	314	58	their	-PRON-	PRP$
cord-003130-p2h8p5bm	314	59	discovery	discovery	NN
cord-003130-p2h8p5bm	314	60	,	,	,
cord-003130-p2h8p5bm	314	61	host	host	NN
cord-003130-p2h8p5bm	314	62	range	range	NN
cord-003130-p2h8p5bm	314	63	,	,	,
cord-003130-p2h8p5bm	314	64	mode	mode	NN
cord-003130-p2h8p5bm	314	65	of	of	IN
cord-003130-p2h8p5bm	314	66	transmission	transmission	NN
cord-003130-p2h8p5bm	314	67	,	,	,
cord-003130-p2h8p5bm	314	68	superinfection	superinfection	NN
cord-003130-p2h8p5bm	314	69	exclusion	exclusion	NN
cord-003130-p2h8p5bm	314	70	potential	potential	NN
cord-003130-p2h8p5bm	314	71	and	and	CC
cord-003130-p2h8p5bm	314	72	genomic	genomic	JJ
cord-003130-p2h8p5bm	314	73	organization	organization	NN
cord-003130-p2h8p5bm	314	74	Role	role	NN
cord-003130-p2h8p5bm	314	75	of	of	IN
cord-003130-p2h8p5bm	314	76	heparan	heparan	JJ
cord-003130-p2h8p5bm	314	77	sulfate	sulfate	NN
cord-003130-p2h8p5bm	314	78	for	for	IN
cord-003130-p2h8p5bm	314	79	attachment	attachment	NN
cord-003130-p2h8p5bm	314	80	and	and	CC
cord-003130-p2h8p5bm	314	81	entry	entry	NN
cord-003130-p2h8p5bm	314	82	of	of	IN
cord-003130-p2h8p5bm	314	83	tick	tick	NN
cord-003130-p2h8p5bm	314	84	-	-	HYPH
cord-003130-p2h8p5bm	314	85	borne	bear	VBN
cord-003130-p2h8p5bm	314	86	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	314	87	virus	virus	NN
cord-003130-p2h8p5bm	314	88	Molecular	molecular	JJ
cord-003130-p2h8p5bm	314	89	mechanisms	mechanism	NNS
cord-003130-p2h8p5bm	314	90	involved	involve	VBN
cord-003130-p2h8p5bm	314	91	in	in	IN
cord-003130-p2h8p5bm	314	92	the	the	DT
cord-003130-p2h8p5bm	314	93	early	early	JJ
cord-003130-p2h8p5bm	314	94	steps	step	NNS
cord-003130-p2h8p5bm	314	95	of	of	IN
cord-003130-p2h8p5bm	314	96	flavivirus	flavivirus	NNP
cord-003130-p2h8p5bm	314	97	cell	cell	NN
cord-003130-p2h8p5bm	314	98	entry	entry	NN
cord-003130-p2h8p5bm	314	99	.	.	.
cord-003130-p2h8p5bm	315	1	Microbes	microbe	NNS
cord-003130-p2h8p5bm	315	2	Infect	infect	VBP
cord-003130-p2h8p5bm	315	3	Rodenhuis	Rodenhuis	NNP
cord-003130-p2h8p5bm	315	4	-	-	HYPH
cord-003130-p2h8p5bm	315	5	Zybert	Zybert	NNP
cord-003130-p2h8p5bm	315	6	,	,	,
cord-003130-p2h8p5bm	315	7	I.	I.	NNP
cord-003130-p2h8p5bm	315	8	;	;	:
cord-003130-p2h8p5bm	315	9	Wilschut	Wilschut	NNP
cord-003130-p2h8p5bm	315	10	,	,	,
cord-003130-p2h8p5bm	315	11	J.	J.	NNP
cord-003130-p2h8p5bm	315	12	Flavivirus	Flavivirus	NNP
cord-003130-p2h8p5bm	315	13	cell	cell	NN
cord-003130-p2h8p5bm	315	14	entry	entry	NN
cord-003130-p2h8p5bm	315	15	and	and	CC
cord-003130-p2h8p5bm	315	16	membrane	membrane	NN
cord-003130-p2h8p5bm	315	17	fusion	fusion	NN
cord-003130-p2h8p5bm	316	1	Flaviviral	Flaviviral	NNP
cord-003130-p2h8p5bm	316	2	replication	replication	NN
cord-003130-p2h8p5bm	316	3	complex	complex	NN
cord-003130-p2h8p5bm	316	4	:	:	:
cord-003130-p2h8p5bm	317	1	Coordination	coordination	NN
cord-003130-p2h8p5bm	317	2	between	between	IN
cord-003130-p2h8p5bm	317	3	RNA	RNA	NNP
cord-003130-p2h8p5bm	317	4	synthesis	synthesis	NN
cord-003130-p2h8p5bm	317	5	and	and	CC
cord-003130-p2h8p5bm	317	6	5	5	CD
cord-003130-p2h8p5bm	317	7	-RNA	-RNA	NNS
cord-003130-p2h8p5bm	317	8	capping	cap	VBG
cord-003130-p2h8p5bm	317	9	De	De	NNP
cord-003130-p2h8p5bm	317	10	novo	novo	NNP
cord-003130-p2h8p5bm	317	11	translation	translation	NN
cord-003130-p2h8p5bm	317	12	initiation	initiation	NN
cord-003130-p2h8p5bm	317	13	on	on	IN
cord-003130-p2h8p5bm	317	14	membrane	membrane	NN
cord-003130-p2h8p5bm	317	15	-	-	HYPH
cord-003130-p2h8p5bm	317	16	bound	bind	VBN
cord-003130-p2h8p5bm	317	17	ribosomes	ribosome	NNS
cord-003130-p2h8p5bm	317	18	as	as	IN
cord-003130-p2h8p5bm	317	19	a	a	DT
cord-003130-p2h8p5bm	317	20	mechanism	mechanism	NN
cord-003130-p2h8p5bm	317	21	for	for	IN
cord-003130-p2h8p5bm	317	22	localization	localization	NN
cord-003130-p2h8p5bm	317	23	of	of	IN
cord-003130-p2h8p5bm	317	24	cytosolic	cytosolic	JJ
cord-003130-p2h8p5bm	317	25	protein	protein	NN
cord-003130-p2h8p5bm	317	26	mrnas	mrnas	NN
cord-003130-p2h8p5bm	317	27	to	to	IN
cord-003130-p2h8p5bm	317	28	the	the	DT
cord-003130-p2h8p5bm	317	29	endoplasmic	endoplasmic	NN
cord-003130-p2h8p5bm	317	30	reticulum	reticulum	NN
cord-003130-p2h8p5bm	318	1	A	a	DT
cord-003130-p2h8p5bm	318	2	three	three	CD
cord-003130-p2h8p5bm	318	3	-	-	HYPH
cord-003130-p2h8p5bm	318	4	dimensional	dimensional	JJ
cord-003130-p2h8p5bm	318	5	comparison	comparison	NN
cord-003130-p2h8p5bm	318	6	of	of	IN
cord-003130-p2h8p5bm	318	7	tick	tick	NN
cord-003130-p2h8p5bm	318	8	-	-	HYPH
cord-003130-p2h8p5bm	318	9	borne	bear	VBN
cord-003130-p2h8p5bm	318	10	flavivirus	flavivirus	JJ
cord-003130-p2h8p5bm	318	11	infection	infection	NN
cord-003130-p2h8p5bm	318	12	in	in	IN
cord-003130-p2h8p5bm	318	13	mammalian	mammalian	JJ
cord-003130-p2h8p5bm	318	14	and	and	CC
cord-003130-p2h8p5bm	318	15	tick	tick	VB
cord-003130-p2h8p5bm	318	16	cell	cell	NN
cord-003130-p2h8p5bm	318	17	lines	line	NNS
cord-003130-p2h8p5bm	318	18	The	the	DT
cord-003130-p2h8p5bm	318	19	endoplasmic	endoplasmic	NN
cord-003130-p2h8p5bm	318	20	reticulum	reticulum	NN
cord-003130-p2h8p5bm	318	21	provides	provide	VBZ
cord-003130-p2h8p5bm	318	22	the	the	DT
cord-003130-p2h8p5bm	318	23	membrane	membrane	NN
cord-003130-p2h8p5bm	318	24	platform	platform	NN
cord-003130-p2h8p5bm	318	25	for	for	IN
cord-003130-p2h8p5bm	318	26	biogenesis	biogenesis	NN
cord-003130-p2h8p5bm	318	27	of	of	IN
cord-003130-p2h8p5bm	318	28	the	the	DT
cord-003130-p2h8p5bm	318	29	flavivirus	flavivirus	JJ
cord-003130-p2h8p5bm	318	30	replication	replication	NN
cord-003130-p2h8p5bm	318	31	complex	complex	JJ
cord-003130-p2h8p5bm	318	32	Tick	tick	NN
cord-003130-p2h8p5bm	318	33	-	-	HYPH
cord-003130-p2h8p5bm	318	34	borne	bear	VBN
cord-003130-p2h8p5bm	318	35	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	318	36	virus	virus	NN
cord-003130-p2h8p5bm	318	37	delays	delay	NNS
cord-003130-p2h8p5bm	318	38	interferon	interferon	VBP
cord-003130-p2h8p5bm	318	39	induction	induction	NN
cord-003130-p2h8p5bm	318	40	and	and	CC
cord-003130-p2h8p5bm	318	41	hides	hide	VBZ
cord-003130-p2h8p5bm	318	42	its	-PRON-	PRP$
cord-003130-p2h8p5bm	318	43	double	double	RB
cord-003130-p2h8p5bm	318	44	-	-	HYPH
cord-003130-p2h8p5bm	318	45	stranded	strand	VBN
cord-003130-p2h8p5bm	318	46	RNA	RNA	NNP
cord-003130-p2h8p5bm	318	47	in	in	IN
cord-003130-p2h8p5bm	318	48	intracellular	intracellular	JJ
cord-003130-p2h8p5bm	318	49	membrane	membrane	NN
cord-003130-p2h8p5bm	318	50	vesicles	vesicle	NNS
cord-003130-p2h8p5bm	318	51	Hiding	hide	VBG
cord-003130-p2h8p5bm	318	52	from	from	IN
cord-003130-p2h8p5bm	318	53	intracellular	intracellular	JJ
cord-003130-p2h8p5bm	318	54	pattern	pattern	NN
cord-003130-p2h8p5bm	318	55	recognition	recognition	NN
cord-003130-p2h8p5bm	318	56	receptors	receptor	NNS
cord-003130-p2h8p5bm	318	57	,	,	,
cord-003130-p2h8p5bm	319	1	a	a	DT
cord-003130-p2h8p5bm	319	2	passive	passive	JJ
cord-003130-p2h8p5bm	319	3	strategy	strategy	NN
cord-003130-p2h8p5bm	319	4	of	of	IN
cord-003130-p2h8p5bm	319	5	flavivirus	flavivirus	JJ
cord-003130-p2h8p5bm	319	6	immune	immune	JJ
cord-003130-p2h8p5bm	319	7	evasion	evasion	NN
cord-003130-p2h8p5bm	319	8	Three	three	CD
cord-003130-p2h8p5bm	319	9	-	-	HYPH
cord-003130-p2h8p5bm	319	10	dimensional	dimensional	JJ
cord-003130-p2h8p5bm	319	11	architecture	architecture	NN
cord-003130-p2h8p5bm	319	12	of	of	IN
cord-003130-p2h8p5bm	319	13	tick	tick	NN
cord-003130-p2h8p5bm	319	14	-	-	HYPH
cord-003130-p2h8p5bm	319	15	borne	bear	VBN
cord-003130-p2h8p5bm	319	16	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	319	17	virus	virus	NN
cord-003130-p2h8p5bm	319	18	replication	replication	NN
cord-003130-p2h8p5bm	319	19	sites	site	NNS
cord-003130-p2h8p5bm	319	20	and	and	CC
cord-003130-p2h8p5bm	319	21	trafficking	trafficking	NN
cord-003130-p2h8p5bm	319	22	of	of	IN
cord-003130-p2h8p5bm	319	23	the	the	DT
cord-003130-p2h8p5bm	319	24	replicated	replicate	VBN
cord-003130-p2h8p5bm	319	25	RNA	RNA	NNP
cord-003130-p2h8p5bm	319	26	Formation	Formation	NNP
cord-003130-p2h8p5bm	319	27	of	of	IN
cord-003130-p2h8p5bm	319	28	membrane	membrane	NN
cord-003130-p2h8p5bm	319	29	-	-	HYPH
cord-003130-p2h8p5bm	319	30	defined	define	VBN
cord-003130-p2h8p5bm	319	31	compartments	compartment	NNS
cord-003130-p2h8p5bm	319	32	by	by	IN
cord-003130-p2h8p5bm	319	33	tick	tick	NN
cord-003130-p2h8p5bm	319	34	-	-	HYPH
cord-003130-p2h8p5bm	319	35	borne	bear	VBN
cord-003130-p2h8p5bm	319	36	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	319	37	virus	virus	NN
cord-003130-p2h8p5bm	319	38	contributes	contribute	VBZ
cord-003130-p2h8p5bm	319	39	to	to	IN
cord-003130-p2h8p5bm	319	40	the	the	DT
cord-003130-p2h8p5bm	319	41	early	early	JJ
cord-003130-p2h8p5bm	319	42	delay	delay	NN
cord-003130-p2h8p5bm	319	43	in	in	IN
cord-003130-p2h8p5bm	319	44	interferon	interferon	NN
cord-003130-p2h8p5bm	319	45	signaling	signal	VBG
cord-003130-p2h8p5bm	319	46	Spatial	Spatial	NNP
cord-003130-p2h8p5bm	319	47	and	and	CC
cord-003130-p2h8p5bm	319	48	temporal	temporal	JJ
cord-003130-p2h8p5bm	319	49	organization	organization	NN
cord-003130-p2h8p5bm	319	50	of	of	IN
cord-003130-p2h8p5bm	319	51	tick	tick	VB
cord-003130-p2h8p5bm	319	52	-	-	HYPH
cord-003130-p2h8p5bm	319	53	borne	bear	VBN
cord-003130-p2h8p5bm	319	54	encephalitis	encephalitis	RB
cord-003130-p2h8p5bm	319	55	flavivirus	flavivirus	NNP
cord-003130-p2h8p5bm	319	56	replicated	replicate	VBD
cord-003130-p2h8p5bm	319	57	RNA	RNA	NNP
cord-003130-p2h8p5bm	319	58	in	in	IN
cord-003130-p2h8p5bm	319	59	living	living	NN
cord-003130-p2h8p5bm	319	60	cells	cell	NNS
cord-003130-p2h8p5bm	319	61	Visual	visual	JJ
cord-003130-p2h8p5bm	319	62	detection	detection	NN
cord-003130-p2h8p5bm	319	63	of	of	IN
cord-003130-p2h8p5bm	319	64	flavivirus	flavivirus	NNP
cord-003130-p2h8p5bm	319	65	RNA	RNA	NNP
cord-003130-p2h8p5bm	319	66	in	in	IN
cord-003130-p2h8p5bm	319	67	living	living	NN
cord-003130-p2h8p5bm	319	68	cells	cell	NNS
cord-003130-p2h8p5bm	319	69	Viperin	Viperin	NNP
cord-003130-p2h8p5bm	319	70	targets	target	VBZ
cord-003130-p2h8p5bm	319	71	flavivirus	flavivirus	JJ
cord-003130-p2h8p5bm	319	72	virulence	virulence	NN
cord-003130-p2h8p5bm	319	73	by	by	IN
cord-003130-p2h8p5bm	319	74	inducing	induce	VBG
cord-003130-p2h8p5bm	319	75	assembly	assembly	NN
cord-003130-p2h8p5bm	319	76	of	of	IN
cord-003130-p2h8p5bm	319	77	non	non	JJ
cord-003130-p2h8p5bm	319	78	-	-	JJ
cord-003130-p2h8p5bm	319	79	infectious	infectious	JJ
cord-003130-p2h8p5bm	319	80	capsid	capsid	NN
cord-003130-p2h8p5bm	319	81	particles	particle	NNS
cord-003130-p2h8p5bm	319	82	N	n	CD
cord-003130-p2h8p5bm	319	83	-	-	HYPH
cord-003130-p2h8p5bm	319	84	linked	link	VBN
cord-003130-p2h8p5bm	319	85	glycan	glycan	NN
cord-003130-p2h8p5bm	319	86	in	in	IN
cord-003130-p2h8p5bm	319	87	tick	tick	NN
cord-003130-p2h8p5bm	319	88	-	-	HYPH
cord-003130-p2h8p5bm	319	89	borne	bear	VBN
cord-003130-p2h8p5bm	319	90	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	319	91	virus	virus	NN
cord-003130-p2h8p5bm	319	92	envelope	envelope	NN
cord-003130-p2h8p5bm	319	93	protein	protein	NN
cord-003130-p2h8p5bm	319	94	affects	affect	VBZ
cord-003130-p2h8p5bm	319	95	viral	viral	JJ
cord-003130-p2h8p5bm	319	96	secretion	secretion	NN
cord-003130-p2h8p5bm	319	97	in	in	IN
cord-003130-p2h8p5bm	319	98	mammalian	mammalian	JJ
cord-003130-p2h8p5bm	319	99	cells	cell	NNS
cord-003130-p2h8p5bm	319	100	,	,	,
cord-003130-p2h8p5bm	319	101	but	but	CC
cord-003130-p2h8p5bm	319	102	not	not	RB
cord-003130-p2h8p5bm	319	103	in	in	IN
cord-003130-p2h8p5bm	319	104	tick	tick	NN
cord-003130-p2h8p5bm	319	105	cells	cell	NNS
cord-003130-p2h8p5bm	319	106	Structure	Structure	NNP
cord-003130-p2h8p5bm	319	107	of	of	IN
cord-003130-p2h8p5bm	319	108	dengue	dengue	NN
cord-003130-p2h8p5bm	319	109	virus	virus	NN
cord-003130-p2h8p5bm	319	110	:	:	:
cord-003130-p2h8p5bm	319	111	Implications	implication	NNS
cord-003130-p2h8p5bm	319	112	for	for	IN
cord-003130-p2h8p5bm	319	113	flavivirus	flavivirus	NNP
cord-003130-p2h8p5bm	319	114	organization	organization	NN
cord-003130-p2h8p5bm	319	115	,	,	,
cord-003130-p2h8p5bm	319	116	maturation	maturation	NN
cord-003130-p2h8p5bm	319	117	,	,	,
cord-003130-p2h8p5bm	319	118	and	and	CC
cord-003130-p2h8p5bm	319	119	fusion	fusion	NN
cord-003130-p2h8p5bm	319	120	Structure	structure	NN
cord-003130-p2h8p5bm	319	121	of	of	IN
cord-003130-p2h8p5bm	319	122	the	the	DT
cord-003130-p2h8p5bm	319	123	immature	immature	JJ
cord-003130-p2h8p5bm	319	124	dengue	dengue	NN
cord-003130-p2h8p5bm	319	125	virus	virus	NN
cord-003130-p2h8p5bm	319	126	at	at	IN
cord-003130-p2h8p5bm	319	127	low	low	JJ
cord-003130-p2h8p5bm	319	128	ph	ph	NNP
cord-003130-p2h8p5bm	319	129	primes	prime	NNS
cord-003130-p2h8p5bm	319	130	proteolytic	proteolytic	JJ
cord-003130-p2h8p5bm	319	131	maturation	maturation	NN
cord-003130-p2h8p5bm	319	132	Cleavage	cleavage	NN
cord-003130-p2h8p5bm	319	133	of	of	IN
cord-003130-p2h8p5bm	319	134	protein	protein	NN
cord-003130-p2h8p5bm	319	135	prm	prm	NNP
cord-003130-p2h8p5bm	319	136	is	be	VBZ
cord-003130-p2h8p5bm	319	137	necessary	necessary	JJ
cord-003130-p2h8p5bm	319	138	for	for	IN
cord-003130-p2h8p5bm	319	139	infection	infection	NN
cord-003130-p2h8p5bm	319	140	of	of	IN
cord-003130-p2h8p5bm	319	141	bhk-21	bhk-21	JJ
cord-003130-p2h8p5bm	319	142	cells	cell	NNS
cord-003130-p2h8p5bm	319	143	by	by	IN
cord-003130-p2h8p5bm	319	144	tick	tick	NN
cord-003130-p2h8p5bm	319	145	-	-	HYPH
cord-003130-p2h8p5bm	319	146	borne	bear	VBN
cord-003130-p2h8p5bm	319	147	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	319	148	virus	virus	NN
cord-003130-p2h8p5bm	319	149	Proteolytic	proteolytic	JJ
cord-003130-p2h8p5bm	319	150	activation	activation	NN
cord-003130-p2h8p5bm	319	151	of	of	IN
cord-003130-p2h8p5bm	319	152	tick	tick	NN
cord-003130-p2h8p5bm	319	153	-	-	HYPH
cord-003130-p2h8p5bm	319	154	borne	bear	VBN
cord-003130-p2h8p5bm	319	155	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	319	156	virus	virus	NN
cord-003130-p2h8p5bm	319	157	by	by	IN
cord-003130-p2h8p5bm	319	158	furin	furin	NNP
cord-003130-p2h8p5bm	319	159	Assembly	Assembly	NNP
cord-003130-p2h8p5bm	319	160	and	and	CC
cord-003130-p2h8p5bm	319	161	maturation	maturation	NN
cord-003130-p2h8p5bm	319	162	of	of	IN
cord-003130-p2h8p5bm	319	163	the	the	DT
cord-003130-p2h8p5bm	319	164	flavivirus	flavivirus	NNP
cord-003130-p2h8p5bm	319	165	kunjin	kunjin	NNP
cord-003130-p2h8p5bm	319	166	virus	virus	NN
cord-003130-p2h8p5bm	319	167	appear	appear	VBP
cord-003130-p2h8p5bm	319	168	to	to	TO
cord-003130-p2h8p5bm	319	169	occur	occur	VB
cord-003130-p2h8p5bm	319	170	in	in	IN
cord-003130-p2h8p5bm	319	171	the	the	DT
cord-003130-p2h8p5bm	319	172	rough	rough	JJ
cord-003130-p2h8p5bm	319	173	endoplasmic	endoplasmic	NN
cord-003130-p2h8p5bm	319	174	reticulum	reticulum	NN
cord-003130-p2h8p5bm	319	175	and	and	CC
cord-003130-p2h8p5bm	319	176	along	along	IN
cord-003130-p2h8p5bm	319	177	the	the	DT
cord-003130-p2h8p5bm	319	178	secretory	secretory	JJ
cord-003130-p2h8p5bm	319	179	pathway	pathway	NN
cord-003130-p2h8p5bm	319	180	,	,	,
cord-003130-p2h8p5bm	319	181	respectively	respectively	RB
cord-003130-p2h8p5bm	319	182	Induction	induction	NN
cord-003130-p2h8p5bm	319	183	and	and	CC
cord-003130-p2h8p5bm	319	184	suppression	suppression	NN
cord-003130-p2h8p5bm	319	185	of	of	IN
cord-003130-p2h8p5bm	319	186	tick	tick	NN
cord-003130-p2h8p5bm	319	187	cell	cell	NN
cord-003130-p2h8p5bm	319	188	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	319	189	RNAi	RNAi	NNS
cord-003130-p2h8p5bm	319	190	responses	response	NNS
cord-003130-p2h8p5bm	319	191	by	by	IN
cord-003130-p2h8p5bm	319	192	tick	tick	NN
cord-003130-p2h8p5bm	319	193	-	-	HYPH
cord-003130-p2h8p5bm	319	194	borne	bear	VBN
cord-003130-p2h8p5bm	319	195	flaviviruses	flaviviruse	VBZ
cord-003130-p2h8p5bm	319	196	Ixodes	Ixodes	NNP
cord-003130-p2h8p5bm	319	197	scapularis	scapularis	NN
cord-003130-p2h8p5bm	319	198	and	and	CC
cord-003130-p2h8p5bm	319	199	ixodes	ixodes	NNP
cord-003130-p2h8p5bm	319	200	ricinus	ricinus	NNP
cord-003130-p2h8p5bm	319	201	tick	tick	VB
cord-003130-p2h8p5bm	319	202	cell	cell	NN
cord-003130-p2h8p5bm	319	203	lines	line	NNS
cord-003130-p2h8p5bm	319	204	respond	respond	VBP
cord-003130-p2h8p5bm	319	205	to	to	IN
cord-003130-p2h8p5bm	319	206	infection	infection	NN
cord-003130-p2h8p5bm	319	207	with	with	IN
cord-003130-p2h8p5bm	319	208	tick	tick	NN
cord-003130-p2h8p5bm	319	209	-	-	HYPH
cord-003130-p2h8p5bm	319	210	borne	bear	VBN
cord-003130-p2h8p5bm	319	211	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	319	212	virus	virus	NN
cord-003130-p2h8p5bm	319	213	:	:	:
cord-003130-p2h8p5bm	319	214	Transcriptomic	Transcriptomic	NNP
cord-003130-p2h8p5bm	319	215	and	and	CC
cord-003130-p2h8p5bm	319	216	proteomic	proteomic	JJ
cord-003130-p2h8p5bm	319	217	analysis	analysis	NN
cord-003130-p2h8p5bm	319	218	Pathogen	Pathogen	NNP
cord-003130-p2h8p5bm	319	219	recognition	recognition	NN
cord-003130-p2h8p5bm	319	220	and	and	CC
cord-003130-p2h8p5bm	319	221	innate	innate	JJ
cord-003130-p2h8p5bm	319	222	immunity	immunity	NN
cord-003130-p2h8p5bm	319	223	Innate	innate	JJ
cord-003130-p2h8p5bm	319	224	immunity	immunity	NN
cord-003130-p2h8p5bm	319	225	and	and	CC
cord-003130-p2h8p5bm	319	226	pathogen	pathogen	NN
cord-003130-p2h8p5bm	319	227	-	-	HYPH
cord-003130-p2h8p5bm	319	228	host	host	NN
cord-003130-p2h8p5bm	319	229	interaction	interaction	NN
cord-003130-p2h8p5bm	319	230	Toll	toll	NN
cord-003130-p2h8p5bm	319	231	-	-	HYPH
cord-003130-p2h8p5bm	319	232	like	like	JJ
cord-003130-p2h8p5bm	319	233	receptor	receptor	NN
cord-003130-p2h8p5bm	319	234	control	control	NN
cord-003130-p2h8p5bm	319	235	of	of	IN
cord-003130-p2h8p5bm	319	236	the	the	DT
cord-003130-p2h8p5bm	319	237	adaptive	adaptive	JJ
cord-003130-p2h8p5bm	319	238	immune	immune	JJ
cord-003130-p2h8p5bm	319	239	responses	response	NNS
cord-003130-p2h8p5bm	319	240	Virus	Virus	NNP
cord-003130-p2h8p5bm	319	241	interference	interference	NN
cord-003130-p2h8p5bm	319	242	.	.	.
cord-003130-p2h8p5bm	320	1	I.	I.	NNP
cord-003130-p2h8p5bm	321	1	The	the	DT
cord-003130-p2h8p5bm	322	1	interferon	interferon	NNP
cord-003130-p2h8p5bm	322	2	Type	Type	NNP
cord-003130-p2h8p5bm	323	1	I	-PRON-	PRP
cord-003130-p2h8p5bm	323	2	interferon	interferon	RB
cord-003130-p2h8p5bm	323	3	protects	protect	VBZ
cord-003130-p2h8p5bm	323	4	mice	mouse	NNS
cord-003130-p2h8p5bm	323	5	from	from	IN
cord-003130-p2h8p5bm	323	6	fatal	fatal	JJ
cord-003130-p2h8p5bm	323	7	neurotropic	neurotropic	JJ
cord-003130-p2h8p5bm	323	8	infection	infection	NN
cord-003130-p2h8p5bm	323	9	with	with	IN
cord-003130-p2h8p5bm	323	10	langat	langat	NNS
cord-003130-p2h8p5bm	323	11	virus	virus	NN
cord-003130-p2h8p5bm	323	12	by	by	IN
cord-003130-p2h8p5bm	323	13	systemic	systemic	JJ
cord-003130-p2h8p5bm	323	14	and	and	CC
cord-003130-p2h8p5bm	323	15	local	local	JJ
cord-003130-p2h8p5bm	323	16	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	323	17	responses	response	NNS
cord-003130-p2h8p5bm	324	1	Fast	fast	JJ
cord-003130-p2h8p5bm	324	2	type	type	NN
cord-003130-p2h8p5bm	325	1	I	-PRON-	PRP
cord-003130-p2h8p5bm	325	2	interferon	interferon	VBD
cord-003130-p2h8p5bm	325	3	response	response	NN
cord-003130-p2h8p5bm	325	4	protects	protect	VBZ
cord-003130-p2h8p5bm	325	5	astrocytes	astrocyte	NNS
cord-003130-p2h8p5bm	325	6	from	from	IN
cord-003130-p2h8p5bm	325	7	flavivirus	flavivirus	JJ
cord-003130-p2h8p5bm	325	8	infection	infection	NN
cord-003130-p2h8p5bm	325	9	and	and	CC
cord-003130-p2h8p5bm	325	10	virus	virus	NN
cord-003130-p2h8p5bm	325	11	-	-	HYPH
cord-003130-p2h8p5bm	325	12	induced	induce	VBN
cord-003130-p2h8p5bm	325	13	cytopathic	cytopathic	JJ
cord-003130-p2h8p5bm	325	14	effects	effect	NNS
cord-003130-p2h8p5bm	326	1	The	the	DT
cord-003130-p2h8p5bm	326	2	role	role	NN
cord-003130-p2h8p5bm	326	3	of	of	IN
cord-003130-p2h8p5bm	326	4	interferon	interferon	NN
cord-003130-p2h8p5bm	326	5	in	in	IN
cord-003130-p2h8p5bm	326	6	tick	tick	NN
cord-003130-p2h8p5bm	326	7	-	-	HYPH
cord-003130-p2h8p5bm	326	8	borne	bear	VBN
cord-003130-p2h8p5bm	326	9	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	326	10	virus	virus	NN
cord-003130-p2h8p5bm	326	11	-	-	HYPH
cord-003130-p2h8p5bm	326	12	infected	infect	VBN
cord-003130-p2h8p5bm	326	13	l	l	NN
cord-003130-p2h8p5bm	326	14	cells	cell	NNS
cord-003130-p2h8p5bm	326	15	.	.	.
cord-003130-p2h8p5bm	327	1	I.	I.	NNP
cord-003130-p2h8p5bm	327	2	Acute	acute	JJ
cord-003130-p2h8p5bm	327	3	infection	infection	NN
cord-003130-p2h8p5bm	328	1	An	an	DT
cord-003130-p2h8p5bm	328	2	interferon	interferon	NN
cord-003130-p2h8p5bm	328	3	-	-	HYPH
cord-003130-p2h8p5bm	328	4	like	like	JJ
cord-003130-p2h8p5bm	328	5	substance	substance	NN
cord-003130-p2h8p5bm	328	6	released	release	VBN
cord-003130-p2h8p5bm	328	7	from	from	IN
cord-003130-p2h8p5bm	328	8	tickborne	tickborne	NNP
cord-003130-p2h8p5bm	328	9	encephalitis	encephalitis	NN
cord-003130-p2h8p5bm	328	10	virus	virus	NN
cord-003130-p2h8p5bm	328	11	-	-	HYPH
cord-003130-p2h8p5bm	328	12	infected	infect	VBN
cord-003130-p2h8p5bm	328	13	chick	chick	NN
cord-003130-p2h8p5bm	328	14	embryo	embryo	NN
cord-003130-p2h8p5bm	328	15	fibroblast	fibroblast	NN
cord-003130-p2h8p5bm	328	16	cells	cell	NNS
cord-003130-p2h8p5bm	328	17	Inhibitors	inhibitor	NNS
cord-003130-p2h8p5bm	328	18	of	of	IN
cord-003130-p2h8p5bm	328	19	the	the	DT
cord-003130-p2h8p5bm	328	20	tick	tick	NN
cord-003130-p2h8p5bm	328	21	-	-	HYPH
cord-003130-p2h8p5bm	328	22	borne	bear	VBN
cord-003130-p2h8p5bm	328	23	,	,	,
cord-003130-p2h8p5bm	328	24	hemorrhagic	hemorrhagic	JJ
cord-003130-p2h8p5bm	328	25	fever	fever	NN
cord-003130-p2h8p5bm	328	26	-	-	HYPH
cord-003130-p2h8p5bm	328	27	associated	associate	VBN
cord-003130-p2h8p5bm	328	28	flaviviruses	flavivirus	NNS
cord-003130-p2h8p5bm	328	29	Peromyscus	Peromyscus	NNP
cord-003130-p2h8p5bm	328	30	leucopus	leucopus	NNP
cord-003130-p2h8p5bm	328	31	mouse	mouse	NNP
cord-003130-p2h8p5bm	328	32	brain	brain	NNP
cord-003130-p2h8p5bm	328	33	transcriptome	transcriptome	NN
cord-003130-p2h8p5bm	328	34	response	response	NN
cord-003130-p2h8p5bm	328	35	to	to	IN
cord-003130-p2h8p5bm	328	36	powassan	powassan	NNP
cord-003130-p2h8p5bm	328	37	virus	virus	NN
cord-003130-p2h8p5bm	328	38	infection	infection	NN
cord-003130-p2h8p5bm	329	1	Innate	innate	JJ
cord-003130-p2h8p5bm	329	2	and	and	CC
cord-003130-p2h8p5bm	329	3	adaptive	adaptive	JJ
cord-003130-p2h8p5bm	329	4	immune	immune	JJ
cord-003130-p2h8p5bm	329	5	responses	response	NNS
cord-003130-p2h8p5bm	329	6	to	to	TO
cord-003130-p2h8p5bm	329	7	tick	tick	VB
cord-003130-p2h8p5bm	329	8	-	-	HYPH
cord-003130-p2h8p5bm	329	9	borne	bear	VBN
cord-003130-p2h8p5bm	329	10	flavivirus	flavivirus	JJ
cord-003130-p2h8p5bm	329	11	infection	infection	NN
cord-003130-p2h8p5bm	329	12	in	in	IN
cord-003130-p2h8p5bm	329	13	sheep	sheep	NN
cord-003130-p2h8p5bm	329	14	Kyasanur	Kyasanur	NNP
cord-003130-p2h8p5bm	329	15	forest	forest	NN
cord-003130-p2h8p5bm	329	16	disease	disease	NN
cord-003130-p2h8p5bm	329	17	virus	virus	NN
cord-003130-p2h8p5bm	329	18	infection	infection	NN
cord-003130-p2h8p5bm	329	19	in	in	IN
cord-003130-p2h8p5bm	329	20	mice	mice	NN
cord-003130-p2h8p5bm	329	21	is	be	VBZ
cord-003130-p2h8p5bm	329	22	associated	associate	VBN
cord-003130-p2h8p5bm	329	23	with	with	IN
cord-003130-p2h8p5bm	329	24	higher	high	JJR
cord-003130-p2h8p5bm	329	25	morbidity	morbidity	NN
cord-003130-p2h8p5bm	329	26	and	and	CC
cord-003130-p2h8p5bm	329	27	mortality	mortality	NN
cord-003130-p2h8p5bm	329	28	than	than	IN
cord-003130-p2h8p5bm	329	29	infection	infection	NN
cord-003130-p2h8p5bm	329	30	with	with	IN
cord-003130-p2h8p5bm	329	31	the	the	DT
cord-003130-p2h8p5bm	329	32	closely	closely	RB
cord-003130-p2h8p5bm	329	33	related	related	JJ
cord-003130-p2h8p5bm	329	34	alkhurma	alkhurma	NNS
cord-003130-p2h8p5bm	329	35	hemorrhagic	hemorrhagic	JJ
cord-003130-p2h8p5bm	329	36	fever	fever	NN
cord-003130-p2h8p5bm	329	37	virus	virus	NN
cord-003130-p2h8p5bm	330	1	The	the	DT
cord-003130-p2h8p5bm	330	2	interferons	interferon	NNS
cord-003130-p2h8p5bm	330	3	and	and	CC
cord-003130-p2h8p5bm	330	4	their	-PRON-	PRP$
cord-003130-p2h8p5bm	330	5	receptors	receptor	NNS
cord-003130-p2h8p5bm	330	6	-	-	:
cord-003130-p2h8p5bm	330	7	Distribution	distribution	NN
cord-003130-p2h8p5bm	330	8	and	and	CC
cord-003130-p2h8p5bm	330	9	regulation	regulation	NN
cord-003130-p2h8p5bm	330	10	Recognition	recognition	NN
cord-003130-p2h8p5bm	330	11	of	of	IN
cord-003130-p2h8p5bm	330	12	viruses	virus	NNS
cord-003130-p2h8p5bm	330	13	by	by	IN
cord-003130-p2h8p5bm	330	14	innate	innate	JJ
cord-003130-p2h8p5bm	330	15	immunity	immunity	NN
cord-003130-p2h8p5bm	330	16	Complex	complex	JJ
cord-003130-p2h8p5bm	330	17	modulation	modulation	NN
cord-003130-p2h8p5bm	330	18	of	of	IN
cord-003130-p2h8p5bm	330	19	cell	cell	NN
cord-003130-p2h8p5bm	330	20	type	type	NN
cord-003130-p2h8p5bm	330	21	-	-	HYPH
cord-003130-p2h8p5bm	330	22	specific	specific	JJ
cord-003130-p2h8p5bm	330	23	signaling	signaling	NN
cord-003130-p2h8p5bm	330	24	in	in	IN
cord-003130-p2h8p5bm	330	25	response	response	NN
cord-003130-p2h8p5bm	330	26	to	to	TO
cord-003130-p2h8p5bm	330	27	type	type	NN
cord-003130-p2h8p5bm	330	28	I	-PRON-	PRP
cord-003130-p2h8p5bm	330	29	interferons	interferon	NNS
cord-003130-p2h8p5bm	331	1	How	how	WRB
cord-003130-p2h8p5bm	331	2	cells	cell	NNS
cord-003130-p2h8p5bm	331	3	respond	respond	VBP
cord-003130-p2h8p5bm	331	4	to	to	IN
cord-003130-p2h8p5bm	331	5	interferons	interferon	NNS
cord-003130-p2h8p5bm	331	6	Functional	functional	JJ
cord-003130-p2h8p5bm	331	7	classification	classification	NN
cord-003130-p2h8p5bm	331	8	of	of	IN
cord-003130-p2h8p5bm	331	9	interferon	interferon	NN
cord-003130-p2h8p5bm	331	10	-	-	HYPH
cord-003130-p2h8p5bm	331	11	stimulated	stimulate	VBN
cord-003130-p2h8p5bm	331	12	genes	gene	NNS
cord-003130-p2h8p5bm	331	13	identified	identify	VBN
cord-003130-p2h8p5bm	331	14	using	use	VBG
cord-003130-p2h8p5bm	331	15	microarrays	microarray	NNS
cord-003130-p2h8p5bm	331	16	Identification	Identification	NNP
cord-003130-p2h8p5bm	331	17	of	of	IN
cord-003130-p2h8p5bm	331	18	genes	gene	NNS
cord-003130-p2h8p5bm	331	19	differentially	differentially	RB
cord-003130-p2h8p5bm	331	20	regulated	regulate	VBN
cord-003130-p2h8p5bm	331	21	by	by	IN
cord-003130-p2h8p5bm	331	22	interferon	interferon	NN
cord-003130-p2h8p5bm	331	23	alpha	alpha	NN
cord-003130-p2h8p5bm	331	24	,	,	,
cord-003130-p2h8p5bm	331	25	beta	beta	NN
cord-003130-p2h8p5bm	331	26	,	,	,
cord-003130-p2h8p5bm	331	27	or	or	CC
cord-003130-p2h8p5bm	331	28	gamma	gamma	NN
cord-003130-p2h8p5bm	331	29	using	use	VBG
cord-003130-p2h8p5bm	331	30	oligonucleotide	oligonucleotide	JJ
cord-003130-p2h8p5bm	331	31	arrays	array	NNS
cord-003130-p2h8p5bm	331	32	Pattern	Pattern	NNP
cord-003130-p2h8p5bm	331	33	recognition	recognition	NN
cord-003130-p2h8p5bm	331	34	receptors	receptor	NNS
cord-003130-p2h8p5bm	331	35	and	and	CC
cord-003130-p2h8p5bm	331	36	inflammation	inflammation	NN
cord-003130-p2h8p5bm	331	37	Recognition	recognition	NN
cord-003130-p2h8p5bm	331	38	of	of	IN
cord-003130-p2h8p5bm	331	39	double	double	RB
cord-003130-p2h8p5bm	331	40	-	-	HYPH
cord-003130-p2h8p5bm	331	41	stranded	strand	VBN
cord-003130-p2h8p5bm	331	42	RNA	RNA	NNP
cord-003130-p2h8p5bm	331	43	and	and	CC
cord-003130-p2h8p5bm	331	44	activation	activation	NN
cord-003130-p2h8p5bm	331	45	of	of	IN
cord-003130-p2h8p5bm	331	46	nf	nf	NN
cord-003130-p2h8p5bm	331	47	-	-	HYPH
cord-003130-p2h8p5bm	331	48	kappab	kappab	NN
cord-003130-p2h8p5bm	331	49	by	by	IN
cord-003130-p2h8p5bm	331	50	toll	toll	NN
cord-003130-p2h8p5bm	331	51	-	-	HYPH
cord-003130-p2h8p5bm	331	52	like	like	JJ
cord-003130-p2h8p5bm	331	53	receptor	receptor	NN
cord-003130-p2h8p5bm	331	54	3	3	CD
cord-003130-p2h8p5bm	331	55	Flavivirus	Flavivirus	NNP
cord-003130-p2h8p5bm	331	56	activation	activation	NN
cord-003130-p2h8p5bm	331	57	of	of	IN
cord-003130-p2h8p5bm	331	58	plasmacytoid	plasmacytoid	NNP
cord-003130-p2h8p5bm	331	59	dendritic	dendritic	JJ
cord-003130-p2h8p5bm	331	60	cells	cell	NNS
cord-003130-p2h8p5bm	331	61	delineates	delineate	VBZ
cord-003130-p2h8p5bm	331	62	key	key	JJ
cord-003130-p2h8p5bm	331	63	elements	element	NNS
cord-003130-p2h8p5bm	331	64	of	of	IN
cord-003130-p2h8p5bm	331	65	tlr7	tlr7	NNP
cord-003130-p2h8p5bm	331	66	signaling	signal	VBG
cord-003130-p2h8p5bm	331	67	beyond	beyond	IN
cord-003130-p2h8p5bm	331	68	endosomal	endosomal	NNP
cord-003130-p2h8p5bm	331	69	recognition	recognition	NN
cord-003130-p2h8p5bm	331	70	Recognition	Recognition	NNP
cord-003130-p2h8p5bm	331	71	of	of	IN
cord-003130-p2h8p5bm	331	72	single	single	RB
cord-003130-p2h8p5bm	331	73	-	-	HYPH
cord-003130-p2h8p5bm	331	74	stranded	strand	VBN
cord-003130-p2h8p5bm	331	75	RNA	RNA	NNP
cord-003130-p2h8p5bm	331	76	viruses	virus	NNS
cord-003130-p2h8p5bm	331	77	by	by	IN
cord-003130-p2h8p5bm	331	78	toll	toll	NN
cord-003130-p2h8p5bm	331	79	-	-	HYPH
cord-003130-p2h8p5bm	331	80	like	like	JJ
cord-003130-p2h8p5bm	331	81	receptor	receptor	NN
cord-003130-p2h8p5bm	331	82	7	7	CD
cord-003130-p2h8p5bm	331	83	Species	species	NN
cord-003130-p2h8p5bm	331	84	-	-	HYPH
cord-003130-p2h8p5bm	331	85	specific	specific	JJ
cord-003130-p2h8p5bm	331	86	recognition	recognition	NN
cord-003130-p2h8p5bm	331	87	of	of	IN
cord-003130-p2h8p5bm	331	88	single	single	RB
cord-003130-p2h8p5bm	331	89	-	-	HYPH
cord-003130-p2h8p5bm	331	90	stranded	strand	VBN
cord-003130-p2h8p5bm	331	91	RNA	RNA	NNP
cord-003130-p2h8p5bm	331	92	via	via	IN
cord-003130-p2h8p5bm	331	93	toll	toll	NN
cord-003130-p2h8p5bm	331	94	-	-	HYPH
cord-003130-p2h8p5bm	331	95	like	like	JJ
cord-003130-p2h8p5bm	331	96	receptor	receptor	NN
cord-003130-p2h8p5bm	331	97	7	7	CD
cord-003130-p2h8p5bm	331	98	and	and	CC
cord-003130-p2h8p5bm	331	99	8	8	CD
cord-003130-p2h8p5bm	332	1	The	the	DT
cord-003130-p2h8p5bm	332	2	RNA	RNA	NNP
cord-003130-p2h8p5bm	332	3	helicase	helicase	NN
cord-003130-p2h8p5bm	332	4	rig	rig	NN
cord-003130-p2h8p5bm	332	5	-	-	:
cord-003130-p2h8p5bm	332	6	i	i	PRP
cord-003130-p2h8p5bm	332	7	has	have	VBZ
cord-003130-p2h8p5bm	332	8	an	an	DT
cord-003130-p2h8p5bm	332	9	essential	essential	JJ
cord-003130-p2h8p5bm	332	10	function	function	NN
cord-003130-p2h8p5bm	332	11	in	in	IN
cord-003130-p2h8p5bm	332	12	double	double	RB
cord-003130-p2h8p5bm	332	13	-	-	HYPH
cord-003130-p2h8p5bm	332	14	stranded	strand	VBN
cord-003130-p2h8p5bm	332	15	RNA	rna	NN
cord-003130-p2h8p5bm	332	16	-	-	HYPH
cord-003130-p2h8p5bm	332	17	induced	induce	VBN
cord-003130-p2h8p5bm	332	18	innate	innate	JJ
cord-003130-p2h8p5bm	332	19	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	332	20	responses	response	NNS
cord-003130-p2h8p5bm	332	21	5	5	CD
cord-003130-p2h8p5bm	333	1	-triphosphate	-triphosphate	.
cord-003130-p2h8p5bm	334	1	RNA	RNA	NNP
cord-003130-p2h8p5bm	334	2	is	be	VBZ
cord-003130-p2h8p5bm	334	3	the	the	DT
cord-003130-p2h8p5bm	334	4	ligand	ligand	NN
cord-003130-p2h8p5bm	334	5	for	for	IN
cord-003130-p2h8p5bm	334	6	rig-	rig-	NN
cord-003130-p2h8p5bm	335	1	i	i	PRP
cord-003130-p2h8p5bm	336	1	Differential	differential	JJ
cord-003130-p2h8p5bm	336	2	recognition	recognition	NN
cord-003130-p2h8p5bm	336	3	of	of	IN
cord-003130-p2h8p5bm	336	4	double	double	RB
cord-003130-p2h8p5bm	336	5	-	-	HYPH
cord-003130-p2h8p5bm	336	6	stranded	strand	VBN
cord-003130-p2h8p5bm	336	7	RNA	RNA	NNP
cord-003130-p2h8p5bm	336	8	by	by	IN
cord-003130-p2h8p5bm	336	9	rig	rig	NN
cord-003130-p2h8p5bm	336	10	-	-	HYPH
cord-003130-p2h8p5bm	336	11	i	i	PRP
cord-003130-p2h8p5bm	336	12	-	-	HYPH
cord-003130-p2h8p5bm	336	13	like	like	JJ
cord-003130-p2h8p5bm	336	14	receptors	receptor	NNS
cord-003130-p2h8p5bm	336	15	in	in	IN
cord-003130-p2h8p5bm	336	16	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	336	17	immunity	immunity	NN
cord-003130-p2h8p5bm	336	18	Role	role	NN
cord-003130-p2h8p5bm	336	19	of	of	IN
cord-003130-p2h8p5bm	336	20	adaptor	adaptor	NN
cord-003130-p2h8p5bm	337	1	trif	trif	NNP
cord-003130-p2h8p5bm	337	2	in	in	IN
cord-003130-p2h8p5bm	337	3	the	the	DT
cord-003130-p2h8p5bm	337	4	myd88-independent	myd88-independent	JJ
cord-003130-p2h8p5bm	337	5	toll	toll	NN
cord-003130-p2h8p5bm	337	6	-	-	HYPH
cord-003130-p2h8p5bm	337	7	like	like	JJ
cord-003130-p2h8p5bm	337	8	receptor	receptor	NN
cord-003130-p2h8p5bm	338	1	signaling	signal	VBG
cord-003130-p2h8p5bm	338	2	pathway	pathway	NN
cord-003130-p2h8p5bm	338	3	Interferon	interferon	NN
cord-003130-p2h8p5bm	338	4	-	-	HYPH
cord-003130-p2h8p5bm	338	5	alpha	alpha	NN
cord-003130-p2h8p5bm	338	6	induction	induction	NN
cord-003130-p2h8p5bm	338	7	through	through	IN
cord-003130-p2h8p5bm	338	8	toll	toll	NN
cord-003130-p2h8p5bm	338	9	-	-	HYPH
cord-003130-p2h8p5bm	338	10	like	like	JJ
cord-003130-p2h8p5bm	338	11	receptors	receptor	NNS
cord-003130-p2h8p5bm	338	12	involves	involve	VBZ
cord-003130-p2h8p5bm	338	13	a	a	DT
cord-003130-p2h8p5bm	338	14	direct	direct	JJ
cord-003130-p2h8p5bm	338	15	interaction	interaction	NN
cord-003130-p2h8p5bm	338	16	of	of	IN
cord-003130-p2h8p5bm	338	17	irf7	irf7	NNP
cord-003130-p2h8p5bm	338	18	with	with	IN
cord-003130-p2h8p5bm	338	19	myd88	myd88	ADD
cord-003130-p2h8p5bm	338	20	and	and	CC
cord-003130-p2h8p5bm	338	21	traf6	traf6	NN
cord-003130-p2h8p5bm	338	22	Identification	identification	NN
cord-003130-p2h8p5bm	338	23	and	and	CC
cord-003130-p2h8p5bm	338	24	characterization	characterization	NN
cord-003130-p2h8p5bm	338	25	of	of	IN
cord-003130-p2h8p5bm	338	26	mavs	mavs	NNPS
cord-003130-p2h8p5bm	338	27	,	,	,
cord-003130-p2h8p5bm	338	28	a	a	DT
cord-003130-p2h8p5bm	338	29	mitochondrial	mitochondrial	JJ
cord-003130-p2h8p5bm	338	30	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	338	31	signaling	signal	VBG
cord-003130-p2h8p5bm	338	32	protein	protein	NN
cord-003130-p2h8p5bm	338	33	that	that	WDT
cord-003130-p2h8p5bm	338	34	activates	activate	VBZ
cord-003130-p2h8p5bm	338	35	nf	nf	NN
cord-003130-p2h8p5bm	338	36	-	-	HYPH
cord-003130-p2h8p5bm	338	37	kappab	kappab	NN
cord-003130-p2h8p5bm	338	38	and	and	CC
cord-003130-p2h8p5bm	338	39	irf	irf	NNP
cord-003130-p2h8p5bm	338	40	3	3	CD
cord-003130-p2h8p5bm	338	41	Ips-1	Ips-1	NNP
cord-003130-p2h8p5bm	338	42	,	,	,
cord-003130-p2h8p5bm	338	43	an	an	DT
cord-003130-p2h8p5bm	338	44	adaptor	adaptor	NN
cord-003130-p2h8p5bm	338	45	triggering	trigger	VBG
cord-003130-p2h8p5bm	338	46	rig	rig	NN
cord-003130-p2h8p5bm	338	47	-	-	HYPH
cord-003130-p2h8p5bm	338	48	i	i	PRP
cord-003130-p2h8p5bm	338	49	-	-	HYPH
cord-003130-p2h8p5bm	338	50	and	and	CC
cord-003130-p2h8p5bm	338	51	mda5-mediated	mda5-mediated	NNP
cord-003130-p2h8p5bm	338	52	type	type	NN
cord-003130-p2h8p5bm	339	1	I	-PRON-	PRP
cord-003130-p2h8p5bm	339	2	interferon	interferon	RB
cord-003130-p2h8p5bm	339	3	induction	induction	NN
cord-003130-p2h8p5bm	340	1	Visa	Visa	NNP
cord-003130-p2h8p5bm	340	2	is	be	VBZ
cord-003130-p2h8p5bm	340	3	an	an	DT
cord-003130-p2h8p5bm	340	4	adapter	adapter	NN
cord-003130-p2h8p5bm	340	5	protein	protein	NN
cord-003130-p2h8p5bm	340	6	required	require	VBN
cord-003130-p2h8p5bm	340	7	for	for	IN
cord-003130-p2h8p5bm	340	8	virus	virus	NN
cord-003130-p2h8p5bm	340	9	-	-	HYPH
cord-003130-p2h8p5bm	340	10	triggered	trigger	VBN
cord-003130-p2h8p5bm	340	11	ifn	ifn	NN
cord-003130-p2h8p5bm	340	12	-	-	HYPH
cord-003130-p2h8p5bm	340	13	beta	beta	NN
cord-003130-p2h8p5bm	340	14	signaling	signal	VBG
cord-003130-p2h8p5bm	340	15	Cardif	Cardif	NNP
cord-003130-p2h8p5bm	340	16	is	be	VBZ
cord-003130-p2h8p5bm	340	17	an	an	DT
cord-003130-p2h8p5bm	340	18	adaptor	adaptor	NN
cord-003130-p2h8p5bm	340	19	protein	protein	NN
cord-003130-p2h8p5bm	340	20	in	in	IN
cord-003130-p2h8p5bm	340	21	the	the	DT
cord-003130-p2h8p5bm	340	22	rig	rig	NN
cord-003130-p2h8p5bm	340	23	-	-	:
cord-003130-p2h8p5bm	340	24	i	i	NNP
cord-003130-p2h8p5bm	340	25	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	340	26	pathway	pathway	NN
cord-003130-p2h8p5bm	340	27	and	and	CC
cord-003130-p2h8p5bm	340	28	is	be	VBZ
cord-003130-p2h8p5bm	340	29	targeted	target	VBN
cord-003130-p2h8p5bm	340	30	by	by	IN
cord-003130-p2h8p5bm	340	31	hepatitis	hepatitis	NNP
cord-003130-p2h8p5bm	340	32	c	c	NNP
cord-003130-p2h8p5bm	340	33	virus	virus	NN
cord-003130-p2h8p5bm	340	34	Master	Master	NNP
cord-003130-p2h8p5bm	340	35	regulators	regulator	NNS
cord-003130-p2h8p5bm	340	36	of	of	IN
cord-003130-p2h8p5bm	340	37	signalling	signal	VBG
cord-003130-p2h8p5bm	340	38	by	by	IN
cord-003130-p2h8p5bm	340	39	toll	toll	NN
cord-003130-p2h8p5bm	340	40	-	-	HYPH
cord-003130-p2h8p5bm	340	41	like	like	JJ
cord-003130-p2h8p5bm	340	42	receptors	receptor	NNS
cord-003130-p2h8p5bm	340	43	and	and	CC
cord-003130-p2h8p5bm	340	44	cytosolic	cytosolic	JJ
cord-003130-p2h8p5bm	340	45	pattern	pattern	NN
cord-003130-p2h8p5bm	340	46	-	-	HYPH
cord-003130-p2h8p5bm	340	47	recognition	recognition	NN
cord-003130-p2h8p5bm	340	48	receptors	receptor	NNS
cord-003130-p2h8p5bm	340	49	Type	type	NN
cord-003130-p2h8p5bm	341	1	I	-PRON-	PRP
cord-003130-p2h8p5bm	342	1	interferon	interferon	NNP
cord-003130-p2h8p5bm	342	2	response	response	NN
cord-003130-p2h8p5bm	342	3	in	in	IN
cord-003130-p2h8p5bm	342	4	olfactory	olfactory	JJ
cord-003130-p2h8p5bm	342	5	bulb	bulb	NN
cord-003130-p2h8p5bm	342	6	,	,	,
cord-003130-p2h8p5bm	342	7	the	the	DT
cord-003130-p2h8p5bm	342	8	site	site	NN
cord-003130-p2h8p5bm	342	9	of	of	IN
cord-003130-p2h8p5bm	342	10	tick	tick	NN
cord-003130-p2h8p5bm	342	11	-	-	HYPH
cord-003130-p2h8p5bm	342	12	borne	bear	VBN
cord-003130-p2h8p5bm	342	13	flavivirus	flavivirus	JJ
cord-003130-p2h8p5bm	342	14	accumulation	accumulation	NN
cord-003130-p2h8p5bm	342	15	,	,	,
cord-003130-p2h8p5bm	342	16	is	be	VBZ
cord-003130-p2h8p5bm	342	17	primarily	primarily	RB
cord-003130-p2h8p5bm	342	18	regulated	regulate	VBN
cord-003130-p2h8p5bm	342	19	by	by	IN
cord-003130-p2h8p5bm	342	20	ips-1	ips-1	NNP
cord-003130-p2h8p5bm	343	1	The	the	DT
cord-003130-p2h8p5bm	343	2	host	host	NN
cord-003130-p2h8p5bm	343	3	cell	cell	NN
cord-003130-p2h8p5bm	343	4	response	response	NN
cord-003130-p2h8p5bm	343	5	to	to	TO
cord-003130-p2h8p5bm	343	6	tick	tick	VB
cord-003130-p2h8p5bm	343	7	-	-	HYPH
cord-003130-p2h8p5bm	343	8	borne	bear	VBN
cord-003130-p2h8p5bm	343	9	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	343	10	virus	virus	NN
cord-003130-p2h8p5bm	343	11	Antiviral	antiviral	JJ
cord-003130-p2h8p5bm	343	12	innate	innate	JJ
cord-003130-p2h8p5bm	343	13	immunity	immunity	NN
cord-003130-p2h8p5bm	343	14	and	and	CC
cord-003130-p2h8p5bm	343	15	stress	stress	NN
cord-003130-p2h8p5bm	343	16	granule	granule	NN
cord-003130-p2h8p5bm	343	17	responses	response	NNS
cord-003130-p2h8p5bm	344	1	The	the	DT
cord-003130-p2h8p5bm	344	2	stress	stress	NN
cord-003130-p2h8p5bm	344	3	granule	granule	NN
cord-003130-p2h8p5bm	344	4	component	component	NN
cord-003130-p2h8p5bm	344	5	tia-1	tia-1	NNP
cord-003130-p2h8p5bm	344	6	binds	bind	VBZ
cord-003130-p2h8p5bm	344	7	tick	tick	NN
cord-003130-p2h8p5bm	344	8	-	-	HYPH
cord-003130-p2h8p5bm	344	9	borne	bear	VBN
cord-003130-p2h8p5bm	344	10	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	344	11	virus	virus	NN
cord-003130-p2h8p5bm	344	12	RNA	RNA	NNP
cord-003130-p2h8p5bm	344	13	and	and	CC
cord-003130-p2h8p5bm	344	14	is	be	VBZ
cord-003130-p2h8p5bm	344	15	recruited	recruit	VBN
cord-003130-p2h8p5bm	344	16	to	to	IN
cord-003130-p2h8p5bm	344	17	perinuclear	perinuclear	NNP
cord-003130-p2h8p5bm	344	18	sites	site	NNS
cord-003130-p2h8p5bm	344	19	of	of	IN
cord-003130-p2h8p5bm	344	20	viral	viral	JJ
cord-003130-p2h8p5bm	344	21	replication	replication	NN
cord-003130-p2h8p5bm	344	22	to	to	TO
cord-003130-p2h8p5bm	344	23	inhibit	inhibit	VB
cord-003130-p2h8p5bm	344	24	viral	viral	JJ
cord-003130-p2h8p5bm	344	25	translation	translation	NN
cord-003130-p2h8p5bm	345	1	Toll	toll	NN
cord-003130-p2h8p5bm	345	2	-	-	HYPH
cord-003130-p2h8p5bm	345	3	like	like	JJ
cord-003130-p2h8p5bm	345	4	receptor	receptor	NN
cord-003130-p2h8p5bm	345	5	7	7	CD
cord-003130-p2h8p5bm	345	6	suppresses	suppress	VBZ
cord-003130-p2h8p5bm	345	7	virus	virus	NN
cord-003130-p2h8p5bm	345	8	replication	replication	NN
cord-003130-p2h8p5bm	345	9	in	in	IN
cord-003130-p2h8p5bm	345	10	neurons	neuron	NNS
cord-003130-p2h8p5bm	345	11	but	but	CC
cord-003130-p2h8p5bm	345	12	does	do	VBZ
cord-003130-p2h8p5bm	345	13	not	not	RB
cord-003130-p2h8p5bm	345	14	affect	affect	VB
cord-003130-p2h8p5bm	345	15	viral	viral	JJ
cord-003130-p2h8p5bm	345	16	pathogenesis	pathogenesis	NN
cord-003130-p2h8p5bm	345	17	in	in	IN
cord-003130-p2h8p5bm	345	18	a	a	DT
cord-003130-p2h8p5bm	345	19	mouse	mouse	NN
cord-003130-p2h8p5bm	345	20	model	model	NN
cord-003130-p2h8p5bm	345	21	of	of	IN
cord-003130-p2h8p5bm	345	22	langat	langat	NNP
cord-003130-p2h8p5bm	345	23	virus	virus	NNP
cord-003130-p2h8p5bm	345	24	infection	infection	NNP
cord-003130-p2h8p5bm	345	25	Association	Association	NNP
cord-003130-p2h8p5bm	345	26	of	of	IN
cord-003130-p2h8p5bm	345	27	single	single	JJ
cord-003130-p2h8p5bm	345	28	nucleotide	nucleotide	JJ
cord-003130-p2h8p5bm	345	29	polymorphism	polymorphism	NN
cord-003130-p2h8p5bm	345	30	rs3775291	rs3775291	VBN
cord-003130-p2h8p5bm	345	31	in	in	IN
cord-003130-p2h8p5bm	345	32	the	the	DT
cord-003130-p2h8p5bm	345	33	coding	code	VBG
cord-003130-p2h8p5bm	345	34	region	region	NN
cord-003130-p2h8p5bm	345	35	of	of	IN
cord-003130-p2h8p5bm	345	36	the	the	DT
cord-003130-p2h8p5bm	345	37	tlr3	tlr3	CD
cord-003130-p2h8p5bm	345	38	gene	gene	NN
cord-003130-p2h8p5bm	345	39	with	with	IN
cord-003130-p2h8p5bm	345	40	predisposition	predisposition	NN
cord-003130-p2h8p5bm	345	41	to	to	TO
cord-003130-p2h8p5bm	345	42	tick	tick	VB
cord-003130-p2h8p5bm	345	43	-	-	HYPH
cord-003130-p2h8p5bm	345	44	borne	bear	VBN
cord-003130-p2h8p5bm	345	45	encephalitis	encephalitis	RB
cord-003130-p2h8p5bm	345	46	in	in	IN
cord-003130-p2h8p5bm	345	47	a	a	DT
cord-003130-p2h8p5bm	345	48	russian	russian	JJ
cord-003130-p2h8p5bm	345	49	population	population	NN
cord-003130-p2h8p5bm	345	50	The	the	DT
cord-003130-p2h8p5bm	345	51	increased	increase	VBN
cord-003130-p2h8p5bm	345	52	concentration	concentration	NN
cord-003130-p2h8p5bm	345	53	of	of	IN
cord-003130-p2h8p5bm	345	54	macrophage	macrophage	NN
cord-003130-p2h8p5bm	345	55	migration	migration	NN
cord-003130-p2h8p5bm	345	56	inhibitory	inhibitory	JJ
cord-003130-p2h8p5bm	345	57	factor	factor	NN
cord-003130-p2h8p5bm	345	58	in	in	IN
cord-003130-p2h8p5bm	345	59	serum	serum	NN
cord-003130-p2h8p5bm	345	60	and	and	CC
cord-003130-p2h8p5bm	345	61	cerebrospinal	cerebrospinal	JJ
cord-003130-p2h8p5bm	345	62	fluid	fluid	NN
cord-003130-p2h8p5bm	345	63	of	of	IN
cord-003130-p2h8p5bm	345	64	patients	patient	NNS
cord-003130-p2h8p5bm	345	65	with	with	IN
cord-003130-p2h8p5bm	345	66	tick	tick	VB
cord-003130-p2h8p5bm	345	67	-	-	HYPH
cord-003130-p2h8p5bm	345	68	borne	bear	VBN
cord-003130-p2h8p5bm	345	69	encephalitis	encephalitis	RB
cord-003130-p2h8p5bm	346	1	A	a	DT
cord-003130-p2h8p5bm	346	2	functional	functional	JJ
cord-003130-p2h8p5bm	346	3	toll	toll	NN
cord-003130-p2h8p5bm	346	4	-	-	HYPH
cord-003130-p2h8p5bm	346	5	like	like	JJ
cord-003130-p2h8p5bm	346	6	receptor	receptor	NN
cord-003130-p2h8p5bm	346	7	3	3	CD
cord-003130-p2h8p5bm	346	8	gene	gene	NN
cord-003130-p2h8p5bm	346	9	(	(	-LRB-
cord-003130-p2h8p5bm	346	10	tlr3	tlr3	NN
cord-003130-p2h8p5bm	346	11	)	)	-RRB-
cord-003130-p2h8p5bm	346	12	may	may	MD
cord-003130-p2h8p5bm	346	13	be	be	VB
cord-003130-p2h8p5bm	346	14	a	a	DT
cord-003130-p2h8p5bm	346	15	risk	risk	NN
cord-003130-p2h8p5bm	346	16	factor	factor	NN
cord-003130-p2h8p5bm	346	17	for	for	IN
cord-003130-p2h8p5bm	346	18	tick	tick	NN
cord-003130-p2h8p5bm	346	19	-	-	HYPH
cord-003130-p2h8p5bm	346	20	borne	bear	VBN
cord-003130-p2h8p5bm	346	21	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	346	22	virus	virus	NN
cord-003130-p2h8p5bm	346	23	(	(	-LRB-
cord-003130-p2h8p5bm	346	24	tbev	tbev	NN
cord-003130-p2h8p5bm	346	25	)	)	-RRB-
cord-003130-p2h8p5bm	346	26	infection	infection	NN
cord-003130-p2h8p5bm	346	27	Polymorphisms	Polymorphisms	NNPS
cord-003130-p2h8p5bm	346	28	in	in	IN
cord-003130-p2h8p5bm	346	29	chemokine	chemokine	NN
cord-003130-p2h8p5bm	346	30	receptor	receptor	NN
cord-003130-p2h8p5bm	346	31	5	5	CD
cord-003130-p2h8p5bm	346	32	and	and	CC
cord-003130-p2h8p5bm	347	1	toll	toll	NN
cord-003130-p2h8p5bm	347	2	-	-	HYPH
cord-003130-p2h8p5bm	347	3	like	like	JJ
cord-003130-p2h8p5bm	347	4	receptor	receptor	NN
cord-003130-p2h8p5bm	347	5	3	3	CD
cord-003130-p2h8p5bm	347	6	genes	gene	NNS
cord-003130-p2h8p5bm	347	7	are	be	VBP
cord-003130-p2h8p5bm	347	8	risk	risk	NN
cord-003130-p2h8p5bm	347	9	factors	factor	NNS
cord-003130-p2h8p5bm	347	10	for	for	IN
cord-003130-p2h8p5bm	347	11	clinical	clinical	JJ
cord-003130-p2h8p5bm	347	12	tick	tick	NN
cord-003130-p2h8p5bm	347	13	-	-	HYPH
cord-003130-p2h8p5bm	347	14	borne	bear	VBN
cord-003130-p2h8p5bm	347	15	encephalitis	encephalitis	RB
cord-003130-p2h8p5bm	347	16	in	in	IN
cord-003130-p2h8p5bm	347	17	the	the	DT
cord-003130-p2h8p5bm	347	18	lithuanian	lithuanian	JJ
cord-003130-p2h8p5bm	347	19	population	population	NN
cord-003130-p2h8p5bm	347	20	Effects	effect	NNS
cord-003130-p2h8p5bm	347	21	of	of	IN
cord-003130-p2h8p5bm	347	22	single	single	JJ
cord-003130-p2h8p5bm	347	23	nucleotide	nucleotide	JJ
cord-003130-p2h8p5bm	347	24	polymorphisms	polymorphism	NNS
cord-003130-p2h8p5bm	347	25	on	on	IN
cord-003130-p2h8p5bm	347	26	toll	toll	NN
cord-003130-p2h8p5bm	347	27	-	-	HYPH
cord-003130-p2h8p5bm	347	28	like	like	JJ
cord-003130-p2h8p5bm	347	29	receptor	receptor	NN
cord-003130-p2h8p5bm	347	30	3	3	CD
cord-003130-p2h8p5bm	347	31	activity	activity	NN
cord-003130-p2h8p5bm	347	32	and	and	CC
cord-003130-p2h8p5bm	347	33	expression	expression	NN
cord-003130-p2h8p5bm	347	34	in	in	IN
cord-003130-p2h8p5bm	347	35	cultured	cultured	JJ
cord-003130-p2h8p5bm	347	36	cells	cell	NNS
cord-003130-p2h8p5bm	347	37	Mechanisms	mechanism	NNS
cord-003130-p2h8p5bm	347	38	of	of	IN
cord-003130-p2h8p5bm	347	39	type	type	NN
cord-003130-p2h8p5bm	348	1	-i	-i	:
cord-003130-p2h8p5bm	348	2	-	-	:
cord-003130-p2h8p5bm	348	3	and	and	CC
cord-003130-p2h8p5bm	348	4	type	type	NN
cord-003130-p2h8p5bm	348	5	-	-	HYPH
cord-003130-p2h8p5bm	348	6	ii	ii	NN
cord-003130-p2h8p5bm	348	7	-	-	HYPH
cord-003130-p2h8p5bm	348	8	interferon	interferon	NN
cord-003130-p2h8p5bm	348	9	-	-	HYPH
cord-003130-p2h8p5bm	348	10	mediated	mediate	VBN
cord-003130-p2h8p5bm	348	11	signalling	signal	VBG
cord-003130-p2h8p5bm	348	12	A	a	DT
cord-003130-p2h8p5bm	348	13	diverse	diverse	JJ
cord-003130-p2h8p5bm	348	14	range	range	NN
cord-003130-p2h8p5bm	348	15	of	of	IN
cord-003130-p2h8p5bm	348	16	gene	gene	NN
cord-003130-p2h8p5bm	348	17	products	product	NNS
cord-003130-p2h8p5bm	348	18	are	be	VBP
cord-003130-p2h8p5bm	348	19	effectors	effector	NNS
cord-003130-p2h8p5bm	348	20	of	of	IN
cord-003130-p2h8p5bm	348	21	the	the	DT
cord-003130-p2h8p5bm	348	22	type	type	NN
cord-003130-p2h8p5bm	349	1	I	-PRON-	PRP
cord-003130-p2h8p5bm	349	2	interferon	interferon	VBP
cord-003130-p2h8p5bm	349	3	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	349	4	response	response	NN
cord-003130-p2h8p5bm	350	1	Interferon	interferon	NN
cord-003130-p2h8p5bm	350	2	-	-	HYPH
cord-003130-p2h8p5bm	350	3	stimulated	stimulate	VBN
cord-003130-p2h8p5bm	350	4	genes	gene	NNS
cord-003130-p2h8p5bm	350	5	:	:	:
cord-003130-p2h8p5bm	350	6	Roles	role	NNS
cord-003130-p2h8p5bm	350	7	in	in	IN
cord-003130-p2h8p5bm	350	8	viral	viral	JJ
cord-003130-p2h8p5bm	350	9	pathogenesis	pathogenesis	NN
cord-003130-p2h8p5bm	350	10	Cell	cell	NN
cord-003130-p2h8p5bm	350	11	-	-	HYPH
cord-003130-p2h8p5bm	350	12	type	type	NN
cord-003130-p2h8p5bm	350	13	-	-	HYPH
cord-003130-p2h8p5bm	350	14	and	and	CC
cord-003130-p2h8p5bm	350	15	region	region	NN
cord-003130-p2h8p5bm	350	16	-	-	HYPH
cord-003130-p2h8p5bm	350	17	specific	specific	JJ
cord-003130-p2h8p5bm	350	18	restriction	restriction	NN
cord-003130-p2h8p5bm	350	19	of	of	IN
cord-003130-p2h8p5bm	350	20	neurotropic	neurotropic	NNP
cord-003130-p2h8p5bm	350	21	flavivirus	flavivirus	NNP
cord-003130-p2h8p5bm	350	22	infection	infection	NN
cord-003130-p2h8p5bm	350	23	by	by	IN
cord-003130-p2h8p5bm	350	24	viperin	viperin	NNP
cord-003130-p2h8p5bm	350	25	Visualization	Visualization	NNP
cord-003130-p2h8p5bm	350	26	of	of	IN
cord-003130-p2h8p5bm	350	27	central	central	JJ
cord-003130-p2h8p5bm	350	28	european	european	JJ
cord-003130-p2h8p5bm	350	29	tick	tick	NN
cord-003130-p2h8p5bm	350	30	-	-	HYPH
cord-003130-p2h8p5bm	350	31	borne	bear	VBN
cord-003130-p2h8p5bm	350	32	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	350	33	infection	infection	NN
cord-003130-p2h8p5bm	350	34	in	in	IN
cord-003130-p2h8p5bm	350	35	fatal	fatal	JJ
cord-003130-p2h8p5bm	350	36	human	human	JJ
cord-003130-p2h8p5bm	350	37	cases	case	NNS
cord-003130-p2h8p5bm	351	1	Contribution	contribution	NN
cord-003130-p2h8p5bm	351	2	to	to	IN
cord-003130-p2h8p5bm	351	3	the	the	DT
cord-003130-p2h8p5bm	351	4	histology	histology	NN
cord-003130-p2h8p5bm	351	5	of	of	IN
cord-003130-p2h8p5bm	351	6	tick	tick	NN
cord-003130-p2h8p5bm	351	7	-	-	HYPH
cord-003130-p2h8p5bm	351	8	borne	bear	VBN
cord-003130-p2h8p5bm	351	9	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	351	10	Infection	infection	NN
cord-003130-p2h8p5bm	351	11	and	and	CC
cord-003130-p2h8p5bm	351	12	injury	injury	NN
cord-003130-p2h8p5bm	351	13	of	of	IN
cord-003130-p2h8p5bm	351	14	human	human	JJ
cord-003130-p2h8p5bm	351	15	astrocytes	astrocyte	NNS
cord-003130-p2h8p5bm	351	16	by	by	IN
cord-003130-p2h8p5bm	351	17	tick	tick	NN
cord-003130-p2h8p5bm	351	18	-	-	HYPH
cord-003130-p2h8p5bm	351	19	borne	bear	VBN
cord-003130-p2h8p5bm	351	20	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	351	21	virus	virus	NN
cord-003130-p2h8p5bm	351	22	Tick	tick	NN
cord-003130-p2h8p5bm	351	23	-	-	HYPH
cord-003130-p2h8p5bm	351	24	borne	bear	VBN
cord-003130-p2h8p5bm	351	25	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	351	26	virus	virus	NN
cord-003130-p2h8p5bm	351	27	infects	infect	VBZ
cord-003130-p2h8p5bm	351	28	rat	rat	NN
cord-003130-p2h8p5bm	351	29	astrocytes	astrocyte	NNS
cord-003130-p2h8p5bm	351	30	but	but	CC
cord-003130-p2h8p5bm	351	31	does	do	VBZ
cord-003130-p2h8p5bm	351	32	not	not	RB
cord-003130-p2h8p5bm	351	33	affect	affect	VB
cord-003130-p2h8p5bm	351	34	their	-PRON-	PRP$
cord-003130-p2h8p5bm	351	35	viability	viability	NN
cord-003130-p2h8p5bm	351	36	Analysis	Analysis	NNP
cord-003130-p2h8p5bm	351	37	of	of	IN
cord-003130-p2h8p5bm	351	38	tick	tick	NN
cord-003130-p2h8p5bm	351	39	-	-	HYPH
cord-003130-p2h8p5bm	351	40	borne	bear	VBN
cord-003130-p2h8p5bm	351	41	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	351	42	virus	virus	NN
cord-003130-p2h8p5bm	351	43	-	-	HYPH
cord-003130-p2h8p5bm	351	44	induced	induce	VBN
cord-003130-p2h8p5bm	351	45	host	host	NN
cord-003130-p2h8p5bm	351	46	responses	response	NNS
cord-003130-p2h8p5bm	351	47	in	in	IN
cord-003130-p2h8p5bm	351	48	human	human	JJ
cord-003130-p2h8p5bm	351	49	cells	cell	NNS
cord-003130-p2h8p5bm	351	50	of	of	IN
cord-003130-p2h8p5bm	351	51	neuronal	neuronal	JJ
cord-003130-p2h8p5bm	351	52	origin	origin	NN
cord-003130-p2h8p5bm	351	53	and	and	CC
cord-003130-p2h8p5bm	351	54	interferon	interferon	NN
cord-003130-p2h8p5bm	351	55	-	-	HYPH
cord-003130-p2h8p5bm	351	56	mediated	mediate	VBN
cord-003130-p2h8p5bm	351	57	protection	protection	NN
cord-003130-p2h8p5bm	351	58	Trim79alpha	trim79alpha	NN
cord-003130-p2h8p5bm	351	59	,	,	,
cord-003130-p2h8p5bm	351	60	an	an	DT
cord-003130-p2h8p5bm	351	61	interferon	interferon	NN
cord-003130-p2h8p5bm	351	62	-	-	HYPH
cord-003130-p2h8p5bm	351	63	stimulated	stimulate	VBN
cord-003130-p2h8p5bm	351	64	gene	gene	NN
cord-003130-p2h8p5bm	351	65	product	product	NN
cord-003130-p2h8p5bm	351	66	,	,	,
cord-003130-p2h8p5bm	351	67	restricts	restrict	VBZ
cord-003130-p2h8p5bm	351	68	tick	tick	NN
cord-003130-p2h8p5bm	351	69	-	-	HYPH
cord-003130-p2h8p5bm	351	70	borne	bear	VBN
cord-003130-p2h8p5bm	351	71	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	351	72	virus	virus	NN
cord-003130-p2h8p5bm	351	73	replication	replication	NN
cord-003130-p2h8p5bm	351	74	by	by	IN
cord-003130-p2h8p5bm	351	75	degrading	degrade	VBG
cord-003130-p2h8p5bm	351	76	the	the	DT
cord-003130-p2h8p5bm	351	77	viral	viral	JJ
cord-003130-p2h8p5bm	351	78	RNA	rna	NN
cord-003130-p2h8p5bm	351	79	polymerase	polymerase	NN
cord-003130-p2h8p5bm	351	80	Inhibition	inhibition	NN
cord-003130-p2h8p5bm	351	81	of	of	IN
cord-003130-p2h8p5bm	351	82	interferon	interferon	NN
cord-003130-p2h8p5bm	351	83	-	-	HYPH
cord-003130-p2h8p5bm	351	84	stimulated	stimulate	VBN
cord-003130-p2h8p5bm	351	85	jak	jak	NNP
cord-003130-p2h8p5bm	351	86	-	-	HYPH
cord-003130-p2h8p5bm	351	87	stat	stat	NN
cord-003130-p2h8p5bm	351	88	signaling	signaling	NN
cord-003130-p2h8p5bm	351	89	by	by	IN
cord-003130-p2h8p5bm	351	90	a	a	DT
cord-003130-p2h8p5bm	351	91	tick	tick	NN
cord-003130-p2h8p5bm	351	92	-	-	HYPH
cord-003130-p2h8p5bm	351	93	borne	bear	VBN
cord-003130-p2h8p5bm	351	94	flavivirus	flavivirus	NN
cord-003130-p2h8p5bm	351	95	and	and	CC
cord-003130-p2h8p5bm	351	96	identification	identification	NN
cord-003130-p2h8p5bm	351	97	of	of	IN
cord-003130-p2h8p5bm	351	98	ns5	ns5	NN
cord-003130-p2h8p5bm	351	99	as	as	IN
cord-003130-p2h8p5bm	351	100	an	an	DT
cord-003130-p2h8p5bm	351	101	interferon	interferon	NN
cord-003130-p2h8p5bm	351	102	antagonist	antagonist	NN
cord-003130-p2h8p5bm	351	103	Viperin	Viperin	NNP
cord-003130-p2h8p5bm	351	104	is	be	VBZ
cord-003130-p2h8p5bm	351	105	an	an	DT
cord-003130-p2h8p5bm	351	106	iron	iron	NN
cord-003130-p2h8p5bm	351	107	-	-	HYPH
cord-003130-p2h8p5bm	351	108	sulfur	sulfur	NN
cord-003130-p2h8p5bm	351	109	protein	protein	NN
cord-003130-p2h8p5bm	351	110	that	that	WDT
cord-003130-p2h8p5bm	351	111	inhibits	inhibit	VBZ
cord-003130-p2h8p5bm	351	112	genome	genome	NN
cord-003130-p2h8p5bm	351	113	synthesis	synthesis	NN
cord-003130-p2h8p5bm	351	114	of	of	IN
cord-003130-p2h8p5bm	351	115	tick	tick	NN
cord-003130-p2h8p5bm	351	116	-	-	HYPH
cord-003130-p2h8p5bm	351	117	borne	bear	VBN
cord-003130-p2h8p5bm	351	118	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	351	119	virus	virus	NN
cord-003130-p2h8p5bm	351	120	via	via	IN
cord-003130-p2h8p5bm	351	121	radical	radical	JJ
cord-003130-p2h8p5bm	351	122	sam	sam	NNP
cord-003130-p2h8p5bm	351	123	domain	domain	NN
cord-003130-p2h8p5bm	351	124	activity	activity	NN
cord-003130-p2h8p5bm	351	125	Viperin	Viperin	NNP
cord-003130-p2h8p5bm	351	126	restricts	restrict	VBZ
cord-003130-p2h8p5bm	351	127	zika	zika	NNP
cord-003130-p2h8p5bm	351	128	virus	virus	NN
cord-003130-p2h8p5bm	351	129	and	and	CC
cord-003130-p2h8p5bm	351	130	tick	tick	VB
cord-003130-p2h8p5bm	351	131	-	-	HYPH
cord-003130-p2h8p5bm	351	132	borne	bear	VBN
cord-003130-p2h8p5bm	351	133	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	351	134	virus	virus	NN
cord-003130-p2h8p5bm	351	135	replication	replication	NN
cord-003130-p2h8p5bm	351	136	by	by	IN
cord-003130-p2h8p5bm	351	137	targeting	target	VBG
cord-003130-p2h8p5bm	351	138	ns3	ns3	NNS
cord-003130-p2h8p5bm	351	139	for	for	IN
cord-003130-p2h8p5bm	351	140	proteasomal	proteasomal	JJ
cord-003130-p2h8p5bm	351	141	degradation	degradation	NN
cord-003130-p2h8p5bm	352	1	The	the	DT
cord-003130-p2h8p5bm	352	2	human	human	JJ
cord-003130-p2h8p5bm	352	3	2	2	CD
cord-003130-p2h8p5bm	352	4	,	,	,
cord-003130-p2h8p5bm	352	5	5	5	CD
cord-003130-p2h8p5bm	352	6	-oligoadenylate	-oligoadenylate	JJ
cord-003130-p2h8p5bm	352	7	synthetase	synthetase	NN
cord-003130-p2h8p5bm	352	8	family	family	NN
cord-003130-p2h8p5bm	352	9	:	:	:
cord-003130-p2h8p5bm	353	1	Interferon	interferon	NN
cord-003130-p2h8p5bm	353	2	-	-	HYPH
cord-003130-p2h8p5bm	353	3	induced	induce	VBN
cord-003130-p2h8p5bm	353	4	proteins	protein	NNS
cord-003130-p2h8p5bm	353	5	with	with	IN
cord-003130-p2h8p5bm	353	6	unique	unique	JJ
cord-003130-p2h8p5bm	353	7	enzymatic	enzymatic	JJ
cord-003130-p2h8p5bm	353	8	properties	property	NNS
cord-003130-p2h8p5bm	354	1	The	the	DT
cord-003130-p2h8p5bm	354	2	nature	nature	NN
cord-003130-p2h8p5bm	354	3	of	of	IN
cord-003130-p2h8p5bm	354	4	the	the	DT
cord-003130-p2h8p5bm	354	5	catalytic	catalytic	JJ
cord-003130-p2h8p5bm	354	6	domain	domain	NN
cord-003130-p2h8p5bm	354	7	of	of	IN
cord-003130-p2h8p5bm	354	8	2	2	CD
cord-003130-p2h8p5bm	355	1	-5	-5	NNP
cord-003130-p2h8p5bm	355	2	-oligoadenylate	-oligoadenylate	HYPH
cord-003130-p2h8p5bm	355	3	synthetases	synthetase	NNS
cord-003130-p2h8p5bm	356	1	Antiviral	antiviral	JJ
cord-003130-p2h8p5bm	356	2	actions	action	NNS
cord-003130-p2h8p5bm	356	3	of	of	IN
cord-003130-p2h8p5bm	356	4	interferons	interferon	NNS
cord-003130-p2h8p5bm	356	5	Variability	variability	NN
cord-003130-p2h8p5bm	356	6	in	in	IN
cord-003130-p2h8p5bm	356	7	the	the	DT
cord-003130-p2h8p5bm	356	8	2	2	CD
cord-003130-p2h8p5bm	356	9	-5	-5	CD
cord-003130-p2h8p5bm	356	10	-oligoadenylate	-oligoadenylate	HYPH
cord-003130-p2h8p5bm	356	11	synthetase	synthetase	NN
cord-003130-p2h8p5bm	356	12	gene	gene	NN
cord-003130-p2h8p5bm	356	13	cluster	cluster	NN
cord-003130-p2h8p5bm	356	14	is	be	VBZ
cord-003130-p2h8p5bm	356	15	associated	associate	VBN
cord-003130-p2h8p5bm	356	16	with	with	IN
cord-003130-p2h8p5bm	356	17	human	human	JJ
cord-003130-p2h8p5bm	356	18	predisposition	predisposition	NN
cord-003130-p2h8p5bm	356	19	to	to	TO
cord-003130-p2h8p5bm	356	20	tick	tick	VB
cord-003130-p2h8p5bm	356	21	-	-	HYPH
cord-003130-p2h8p5bm	356	22	borne	bear	VBN
cord-003130-p2h8p5bm	356	23	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	356	24	virus	virus	NN
cord-003130-p2h8p5bm	356	25	-	-	HYPH
cord-003130-p2h8p5bm	356	26	induced	induce	VBN
cord-003130-p2h8p5bm	356	27	disease	disease	NN
cord-003130-p2h8p5bm	356	28	Susceptibility	Susceptibility	NNP
cord-003130-p2h8p5bm	356	29	to	to	IN
cord-003130-p2h8p5bm	356	30	flavivirus	flavivirus	JJ
cord-003130-p2h8p5bm	356	31	-	-	HYPH
cord-003130-p2h8p5bm	356	32	specific	specific	JJ
cord-003130-p2h8p5bm	356	33	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	356	34	response	response	NN
cord-003130-p2h8p5bm	356	35	of	of	IN
cord-003130-p2h8p5bm	356	36	oas1b	oas1b	NN
cord-003130-p2h8p5bm	356	37	affects	affect	VBZ
cord-003130-p2h8p5bm	356	38	the	the	DT
cord-003130-p2h8p5bm	356	39	neurovirulence	neurovirulence	NN
cord-003130-p2h8p5bm	356	40	of	of	IN
cord-003130-p2h8p5bm	356	41	the	the	DT
cord-003130-p2h8p5bm	356	42	far	far	JJ
cord-003130-p2h8p5bm	356	43	-	-	HYPH
cord-003130-p2h8p5bm	356	44	eastern	eastern	JJ
cord-003130-p2h8p5bm	356	45	subtype	subtype	NN
cord-003130-p2h8p5bm	356	46	of	of	IN
cord-003130-p2h8p5bm	356	47	tick	tick	NN
cord-003130-p2h8p5bm	356	48	-	-	HYPH
cord-003130-p2h8p5bm	356	49	borne	bear	VBN
cord-003130-p2h8p5bm	356	50	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	356	51	virus	virus	NN
cord-003130-p2h8p5bm	356	52	Trim	trim	NN
cord-003130-p2h8p5bm	356	53	family	family	NN
cord-003130-p2h8p5bm	356	54	proteins	protein	NNS
cord-003130-p2h8p5bm	356	55	:	:	:
cord-003130-p2h8p5bm	356	56	Retroviral	retroviral	JJ
cord-003130-p2h8p5bm	356	57	restriction	restriction	NN
cord-003130-p2h8p5bm	356	58	and	and	CC
cord-003130-p2h8p5bm	356	59	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	356	60	defence	defence	NN
cord-003130-p2h8p5bm	356	61	Viperin	Viperin	NNP
cord-003130-p2h8p5bm	356	62	(	(	-LRB-
cord-003130-p2h8p5bm	356	63	cig5	cig5	NNP
cord-003130-p2h8p5bm	356	64	)	)	-RRB-
cord-003130-p2h8p5bm	356	65	,	,	,
cord-003130-p2h8p5bm	356	66	an	an	DT
cord-003130-p2h8p5bm	356	67	ifn	ifn	NN
cord-003130-p2h8p5bm	356	68	-	-	HYPH
cord-003130-p2h8p5bm	356	69	inducible	inducible	JJ
cord-003130-p2h8p5bm	356	70	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	356	71	protein	protein	NN
cord-003130-p2h8p5bm	356	72	directly	directly	RB
cord-003130-p2h8p5bm	356	73	induced	induce	VBN
cord-003130-p2h8p5bm	356	74	by	by	IN
cord-003130-p2h8p5bm	356	75	human	human	JJ
cord-003130-p2h8p5bm	356	76	cytomegalovirus	cytomegalovirus	NN
cord-003130-p2h8p5bm	356	77	The	the	DT
cord-003130-p2h8p5bm	356	78	role	role	NN
cord-003130-p2h8p5bm	356	79	of	of	IN
cord-003130-p2h8p5bm	356	80	viperin	viperin	NNP
cord-003130-p2h8p5bm	356	81	in	in	IN
cord-003130-p2h8p5bm	356	82	the	the	DT
cord-003130-p2h8p5bm	356	83	innate	innate	JJ
cord-003130-p2h8p5bm	356	84	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	356	85	response	response	NN
cord-003130-p2h8p5bm	356	86	Differential	differential	JJ
cord-003130-p2h8p5bm	356	87	innate	innate	JJ
cord-003130-p2h8p5bm	356	88	immune	immune	JJ
cord-003130-p2h8p5bm	356	89	response	response	NN
cord-003130-p2h8p5bm	356	90	programs	program	NNS
cord-003130-p2h8p5bm	356	91	in	in	IN
cord-003130-p2h8p5bm	356	92	neuronal	neuronal	JJ
cord-003130-p2h8p5bm	356	93	subtypes	subtype	NNS
cord-003130-p2h8p5bm	356	94	determine	determine	VBP
cord-003130-p2h8p5bm	356	95	susceptibility	susceptibility	NN
cord-003130-p2h8p5bm	356	96	to	to	IN
cord-003130-p2h8p5bm	356	97	infection	infection	NN
cord-003130-p2h8p5bm	356	98	in	in	IN
cord-003130-p2h8p5bm	356	99	the	the	DT
cord-003130-p2h8p5bm	356	100	brain	brain	NN
cord-003130-p2h8p5bm	356	101	by	by	IN
cord-003130-p2h8p5bm	356	102	positive	positive	JJ
cord-003130-p2h8p5bm	356	103	-	-	HYPH
cord-003130-p2h8p5bm	356	104	stranded	strand	VBN
cord-003130-p2h8p5bm	356	105	RNA	rna	NN
cord-003130-p2h8p5bm	356	106	viruses	virus	NNS
cord-003130-p2h8p5bm	357	1	The	the	DT
cord-003130-p2h8p5bm	357	2	interferon	interferon	NN
cord-003130-p2h8p5bm	357	3	-	-	HYPH
cord-003130-p2h8p5bm	357	4	inducible	inducible	JJ
cord-003130-p2h8p5bm	357	5	gene	gene	NN
cord-003130-p2h8p5bm	357	6	viperin	viperin	NNP
cord-003130-p2h8p5bm	357	7	restricts	restrict	VBZ
cord-003130-p2h8p5bm	357	8	west	west	NNP
cord-003130-p2h8p5bm	357	9	nile	nile	NNP
cord-003130-p2h8p5bm	357	10	virus	virus	NN
cord-003130-p2h8p5bm	357	11	pathogenesis	pathogenesis	NN
cord-003130-p2h8p5bm	357	12	Viperin	Viperin	NNP
cord-003130-p2h8p5bm	357	13	is	be	VBZ
cord-003130-p2h8p5bm	357	14	induced	induce	VBN
cord-003130-p2h8p5bm	357	15	following	follow	VBG
cord-003130-p2h8p5bm	357	16	dengue	dengue	NN
cord-003130-p2h8p5bm	357	17	virus	virus	NN
cord-003130-p2h8p5bm	357	18	type-2	type-2	NNP
cord-003130-p2h8p5bm	357	19	(	(	-LRB-
cord-003130-p2h8p5bm	357	20	denv-2	denv-2	NN
cord-003130-p2h8p5bm	357	21	)	)	-RRB-
cord-003130-p2h8p5bm	357	22	infection	infection	NN
cord-003130-p2h8p5bm	357	23	and	and	CC
cord-003130-p2h8p5bm	357	24	has	have	VBZ
cord-003130-p2h8p5bm	357	25	anti	anti	JJ
cord-003130-p2h8p5bm	357	26	-	-	JJ
cord-003130-p2h8p5bm	357	27	viral	viral	JJ
cord-003130-p2h8p5bm	357	28	actions	action	NNS
cord-003130-p2h8p5bm	357	29	requiring	require	VBG
cord-003130-p2h8p5bm	357	30	the	the	DT
cord-003130-p2h8p5bm	357	31	c	c	NN
cord-003130-p2h8p5bm	357	32	-	-	HYPH
cord-003130-p2h8p5bm	357	33	terminal	terminal	JJ
cord-003130-p2h8p5bm	357	34	end	end	NN
cord-003130-p2h8p5bm	357	35	of	of	IN
cord-003130-p2h8p5bm	357	36	viperin	viperin	NNP
cord-003130-p2h8p5bm	357	37	Viperin	Viperin	NNP
cord-003130-p2h8p5bm	357	38	is	be	VBZ
cord-003130-p2h8p5bm	357	39	an	an	DT
cord-003130-p2h8p5bm	357	40	important	important	JJ
cord-003130-p2h8p5bm	357	41	host	host	NN
cord-003130-p2h8p5bm	357	42	restriction	restriction	NN
cord-003130-p2h8p5bm	357	43	factor	factor	NN
cord-003130-p2h8p5bm	357	44	in	in	IN
cord-003130-p2h8p5bm	357	45	control	control	NN
cord-003130-p2h8p5bm	357	46	of	of	IN
cord-003130-p2h8p5bm	357	47	zika	zika	NNP
cord-003130-p2h8p5bm	357	48	virus	virus	NN
cord-003130-p2h8p5bm	357	49	infection	infection	NN
cord-003130-p2h8p5bm	358	1	The	the	DT
cord-003130-p2h8p5bm	358	2	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	358	3	protein	protein	NN
cord-003130-p2h8p5bm	358	4	viperin	viperin	NNP
cord-003130-p2h8p5bm	358	5	inhibits	inhibit	VBZ
cord-003130-p2h8p5bm	358	6	hepatitis	hepatitis	NNP
cord-003130-p2h8p5bm	358	7	c	c	NNP
cord-003130-p2h8p5bm	358	8	virus	virus	NN
cord-003130-p2h8p5bm	358	9	replication	replication	NN
cord-003130-p2h8p5bm	358	10	via	via	IN
cord-003130-p2h8p5bm	358	11	interaction	interaction	NN
cord-003130-p2h8p5bm	358	12	with	with	IN
cord-003130-p2h8p5bm	358	13	nonstructural	nonstructural	JJ
cord-003130-p2h8p5bm	358	14	protein	protein	NN
cord-003130-p2h8p5bm	358	15	5a	5a	NN
cord-003130-p2h8p5bm	358	16	Viperin	Viperin	NNP
cord-003130-p2h8p5bm	358	17	:	:	:
cord-003130-p2h8p5bm	359	1	A	a	DT
cord-003130-p2h8p5bm	359	2	multifunctional	multifunctional	JJ
cord-003130-p2h8p5bm	359	3	,	,	,
cord-003130-p2h8p5bm	359	4	interferon	interferon	NN
cord-003130-p2h8p5bm	359	5	-	-	HYPH
cord-003130-p2h8p5bm	359	6	inducible	inducible	JJ
cord-003130-p2h8p5bm	359	7	protein	protein	NN
cord-003130-p2h8p5bm	359	8	that	that	WDT
cord-003130-p2h8p5bm	359	9	regulates	regulate	VBZ
cord-003130-p2h8p5bm	359	10	virus	virus	NN
cord-003130-p2h8p5bm	359	11	replication	replication	NN
cord-003130-p2h8p5bm	360	1	The	the	DT
cord-003130-p2h8p5bm	360	2	interferon	interferon	NN
cord-003130-p2h8p5bm	360	3	inducible	inducible	JJ
cord-003130-p2h8p5bm	360	4	gene	gene	NN
cord-003130-p2h8p5bm	360	5	:	:	:
cord-003130-p2h8p5bm	361	1	Viperin	Viperin	NNP
cord-003130-p2h8p5bm	361	2	Structural	structural	JJ
cord-003130-p2h8p5bm	361	3	characterization	characterization	NN
cord-003130-p2h8p5bm	361	4	reveals	reveal	VBZ
cord-003130-p2h8p5bm	361	5	that	that	IN
cord-003130-p2h8p5bm	361	6	viperin	viperin	NNP
cord-003130-p2h8p5bm	361	7	is	be	VBZ
cord-003130-p2h8p5bm	361	8	a	a	DT
cord-003130-p2h8p5bm	361	9	radical	radical	JJ
cord-003130-p2h8p5bm	361	10	s	s	NN
cord-003130-p2h8p5bm	361	11	-	-	HYPH
cord-003130-p2h8p5bm	361	12	adenosyl	adenosyl	NN
cord-003130-p2h8p5bm	361	13	-	-	HYPH
cord-003130-p2h8p5bm	361	14	l	l	NN
cord-003130-p2h8p5bm	361	15	-	-	HYPH
cord-003130-p2h8p5bm	361	16	methionine	methionine	NNP
cord-003130-p2h8p5bm	361	17	(	(	-LRB-
cord-003130-p2h8p5bm	361	18	sam	sam	NNP
cord-003130-p2h8p5bm	361	19	)	)	-RRB-
cord-003130-p2h8p5bm	361	20	enzyme	enzyme	VBZ
cord-003130-p2h8p5bm	361	21	Cellular	cellular	JJ
cord-003130-p2h8p5bm	361	22	requirements	requirement	NNS
cord-003130-p2h8p5bm	361	23	for	for	IN
cord-003130-p2h8p5bm	361	24	iron	iron	NN
cord-003130-p2h8p5bm	361	25	-	-	HYPH
cord-003130-p2h8p5bm	361	26	sulfur	sulfur	NN
cord-003130-p2h8p5bm	361	27	cluster	cluster	NN
cord-003130-p2h8p5bm	361	28	insertion	insertion	NN
cord-003130-p2h8p5bm	361	29	into	into	IN
cord-003130-p2h8p5bm	361	30	the	the	DT
cord-003130-p2h8p5bm	361	31	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	361	32	radical	radical	NNP
cord-003130-p2h8p5bm	361	33	sam	sam	NNP
cord-003130-p2h8p5bm	361	34	protein	protein	NNP
cord-003130-p2h8p5bm	361	35	viperin	viperin	NNP
cord-003130-p2h8p5bm	361	36	Structural	Structural	NNP
cord-003130-p2h8p5bm	361	37	studies	study	NNS
cord-003130-p2h8p5bm	361	38	of	of	IN
cord-003130-p2h8p5bm	361	39	viperin	viperin	NNP
cord-003130-p2h8p5bm	361	40	,	,	,
cord-003130-p2h8p5bm	361	41	an	an	DT
cord-003130-p2h8p5bm	361	42	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	361	43	radical	radical	JJ
cord-003130-p2h8p5bm	361	44	sam	sam	NNP
cord-003130-p2h8p5bm	361	45	enzyme	enzyme	NNP
cord-003130-p2h8p5bm	362	1	A	a	DT
cord-003130-p2h8p5bm	362	2	unifying	unifying	JJ
cord-003130-p2h8p5bm	362	3	view	view	NN
cord-003130-p2h8p5bm	362	4	of	of	IN
cord-003130-p2h8p5bm	362	5	the	the	DT
cord-003130-p2h8p5bm	362	6	broad	broad	JJ
cord-003130-p2h8p5bm	362	7	-	-	HYPH
cord-003130-p2h8p5bm	362	8	spectrum	spectrum	NN
cord-003130-p2h8p5bm	362	9	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	362	10	activity	activity	NN
cord-003130-p2h8p5bm	362	11	of	of	IN
cord-003130-p2h8p5bm	362	12	rsad2	rsad2	NN
cord-003130-p2h8p5bm	362	13	(	(	-LRB-
cord-003130-p2h8p5bm	362	14	viperin	viperin	NNP
cord-003130-p2h8p5bm	362	15	)	)	-RRB-
cord-003130-p2h8p5bm	362	16	based	base	VBN
cord-003130-p2h8p5bm	362	17	on	on	IN
cord-003130-p2h8p5bm	362	18	its	-PRON-	PRP$
cord-003130-p2h8p5bm	362	19	radical	radical	JJ
cord-003130-p2h8p5bm	362	20	-	-	HYPH
cord-003130-p2h8p5bm	362	21	sam	sam	NNP
cord-003130-p2h8p5bm	362	22	chemistry	chemistry	NN
cord-003130-p2h8p5bm	363	1	A	a	DT
cord-003130-p2h8p5bm	363	2	b12-dependent	b12-dependent	CD
cord-003130-p2h8p5bm	363	3	radical	radical	JJ
cord-003130-p2h8p5bm	363	4	sam	sam	NNP
cord-003130-p2h8p5bm	363	5	enzyme	enzyme	NN
cord-003130-p2h8p5bm	363	6	involved	involve	VBN
cord-003130-p2h8p5bm	363	7	in	in	IN
cord-003130-p2h8p5bm	363	8	oxetanocin	oxetanocin	NNP
cord-003130-p2h8p5bm	363	9	a	a	DT
cord-003130-p2h8p5bm	363	10	biosynthesis	biosynthesis	NN
cord-003130-p2h8p5bm	363	11	Quantitative	quantitative	JJ
cord-003130-p2h8p5bm	363	12	proteomic	proteomic	JJ
cord-003130-p2h8p5bm	363	13	analysis	analysis	NN
cord-003130-p2h8p5bm	363	14	of	of	IN
cord-003130-p2h8p5bm	363	15	host	host	NN
cord-003130-p2h8p5bm	363	16	-	-	HYPH
cord-003130-p2h8p5bm	363	17	virus	virus	NN
cord-003130-p2h8p5bm	363	18	interactions	interaction	NNS
cord-003130-p2h8p5bm	363	19	reveals	reveal	VBZ
cord-003130-p2h8p5bm	363	20	a	a	DT
cord-003130-p2h8p5bm	363	21	role	role	NN
cord-003130-p2h8p5bm	363	22	for	for	IN
cord-003130-p2h8p5bm	363	23	golgi	golgi	NNP
cord-003130-p2h8p5bm	363	24	brefeldin	brefeldin	NNP
cord-003130-p2h8p5bm	363	25	a	a	DT
cord-003130-p2h8p5bm	363	26	resistance	resistance	NN
cord-003130-p2h8p5bm	363	27	factor	factor	NN
cord-003130-p2h8p5bm	363	28	1	1	CD
cord-003130-p2h8p5bm	363	29	(	(	-LRB-
cord-003130-p2h8p5bm	363	30	gbf1	gbf1	NNP
cord-003130-p2h8p5bm	363	31	)	)	-RRB-
cord-003130-p2h8p5bm	363	32	in	in	IN
cord-003130-p2h8p5bm	363	33	dengue	dengue	NN
cord-003130-p2h8p5bm	363	34	infection	infection	NN
cord-003130-p2h8p5bm	363	35	Identification	identification	NN
cord-003130-p2h8p5bm	363	36	of	of	IN
cord-003130-p2h8p5bm	363	37	class	class	NNP
cord-003130-p2h8p5bm	363	38	ii	ii	NNP
cord-003130-p2h8p5bm	363	39	adp	adp	NNP
cord-003130-p2h8p5bm	363	40	-	-	HYPH
cord-003130-p2h8p5bm	363	41	ribosylation	ribosylation	NN
cord-003130-p2h8p5bm	363	42	factors	factor	NNS
cord-003130-p2h8p5bm	363	43	as	as	IN
cord-003130-p2h8p5bm	363	44	cellular	cellular	JJ
cord-003130-p2h8p5bm	363	45	factors	factor	NNS
cord-003130-p2h8p5bm	363	46	required	require	VBN
cord-003130-p2h8p5bm	363	47	for	for	IN
cord-003130-p2h8p5bm	363	48	hepatitis	hepatitis	NNP
cord-003130-p2h8p5bm	363	49	c	c	NNP
cord-003130-p2h8p5bm	363	50	virus	virus	NN
cord-003130-p2h8p5bm	363	51	replication	replication	NN
cord-003130-p2h8p5bm	364	1	A	a	DT
cord-003130-p2h8p5bm	364	2	kinome	kinome	NN
cord-003130-p2h8p5bm	364	3	-	-	HYPH
cord-003130-p2h8p5bm	364	4	wide	wide	JJ
cord-003130-p2h8p5bm	364	5	small	small	JJ
cord-003130-p2h8p5bm	364	6	interfering	interfere	VBG
cord-003130-p2h8p5bm	364	7	RNA	RNA	NNP
cord-003130-p2h8p5bm	364	8	screen	screen	NN
cord-003130-p2h8p5bm	364	9	identifies	identify	VBZ
cord-003130-p2h8p5bm	364	10	proviral	proviral	JJ
cord-003130-p2h8p5bm	364	11	and	and	CC
cord-003130-p2h8p5bm	364	12	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	364	13	host	host	NN
cord-003130-p2h8p5bm	364	14	factors	factor	NNS
cord-003130-p2h8p5bm	364	15	in	in	IN
cord-003130-p2h8p5bm	364	16	severe	severe	JJ
cord-003130-p2h8p5bm	364	17	acute	acute	JJ
cord-003130-p2h8p5bm	364	18	respiratory	respiratory	JJ
cord-003130-p2h8p5bm	364	19	syndrome	syndrome	NN
cord-003130-p2h8p5bm	364	20	coronavirus	coronavirus	NN
cord-003130-p2h8p5bm	364	21	replication	replication	NN
cord-003130-p2h8p5bm	364	22	,	,	,
cord-003130-p2h8p5bm	364	23	including	include	VBG
cord-003130-p2h8p5bm	364	24	double	double	RB
cord-003130-p2h8p5bm	364	25	-	-	HYPH
cord-003130-p2h8p5bm	364	26	stranded	strand	VBN
cord-003130-p2h8p5bm	364	27	RNA	RNA	NNP
cord-003130-p2h8p5bm	364	28	-	-	HYPH
cord-003130-p2h8p5bm	364	29	activated	activate	VBN
cord-003130-p2h8p5bm	364	30	protein	protein	NN
cord-003130-p2h8p5bm	364	31	kinase	kinase	NN
cord-003130-p2h8p5bm	364	32	and	and	CC
cord-003130-p2h8p5bm	364	33	early	early	JJ
cord-003130-p2h8p5bm	364	34	secretory	secretory	JJ
cord-003130-p2h8p5bm	364	35	pathway	pathway	NN
cord-003130-p2h8p5bm	364	36	proteins	protein	NNS
cord-003130-p2h8p5bm	364	37	Role	role	NN
cord-003130-p2h8p5bm	364	38	of	of	IN
cord-003130-p2h8p5bm	364	39	the	the	DT
cord-003130-p2h8p5bm	364	40	gtpase	gtpase	NNP
cord-003130-p2h8p5bm	364	41	rab1b	rab1b	NN
cord-003130-p2h8p5bm	364	42	in	in	IN
cord-003130-p2h8p5bm	364	43	ebolavirus	ebolavirus	NN
cord-003130-p2h8p5bm	364	44	particle	particle	NN
cord-003130-p2h8p5bm	364	45	formation	formation	NN
cord-003130-p2h8p5bm	364	46	Enhancement	Enhancement	NNP
cord-003130-p2h8p5bm	364	47	of	of	IN
cord-003130-p2h8p5bm	364	48	tick	tick	NN
cord-003130-p2h8p5bm	364	49	-	-	HYPH
cord-003130-p2h8p5bm	364	50	borne	bear	VBN
cord-003130-p2h8p5bm	364	51	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	364	52	virus	virus	NN
cord-003130-p2h8p5bm	364	53	transmission	transmission	NN
cord-003130-p2h8p5bm	364	54	by	by	IN
cord-003130-p2h8p5bm	364	55	tick	tick	NN
cord-003130-p2h8p5bm	364	56	salivary	salivary	NNP
cord-003130-p2h8p5bm	364	57	gland	gland	NN
cord-003130-p2h8p5bm	364	58	extracts	extract	NNS
cord-003130-p2h8p5bm	364	59	Tick	tick	VBP
cord-003130-p2h8p5bm	364	60	salivary	salivary	NN
cord-003130-p2h8p5bm	364	61	compounds	compound	NNS
cord-003130-p2h8p5bm	364	62	:	:	:
cord-003130-p2h8p5bm	365	1	Their	-PRON-	PRP$
cord-003130-p2h8p5bm	365	2	role	role	NN
cord-003130-p2h8p5bm	365	3	in	in	IN
cord-003130-p2h8p5bm	365	4	modulation	modulation	NN
cord-003130-p2h8p5bm	365	5	of	of	IN
cord-003130-p2h8p5bm	365	6	host	host	NN
cord-003130-p2h8p5bm	365	7	defences	defence	NNS
cord-003130-p2h8p5bm	365	8	and	and	CC
cord-003130-p2h8p5bm	365	9	pathogen	pathogen	NN
cord-003130-p2h8p5bm	365	10	transmission	transmission	NN
cord-003130-p2h8p5bm	366	1	Innate	innate	JJ
cord-003130-p2h8p5bm	366	2	immune	immune	JJ
cord-003130-p2h8p5bm	366	3	evasion	evasion	NN
cord-003130-p2h8p5bm	366	4	mediated	mediate	VBN
cord-003130-p2h8p5bm	366	5	by	by	IN
cord-003130-p2h8p5bm	366	6	flaviviridae	flaviviridae	NN
cord-003130-p2h8p5bm	366	7	non	non	JJ
cord-003130-p2h8p5bm	366	8	-	-	JJ
cord-003130-p2h8p5bm	366	9	structural	structural	JJ
cord-003130-p2h8p5bm	366	10	proteins	protein	NNS
cord-003130-p2h8p5bm	366	11	Tick	tick	VB
cord-003130-p2h8p5bm	366	12	-	-	HYPH
cord-003130-p2h8p5bm	366	13	borne	bear	VBN
cord-003130-p2h8p5bm	366	14	encephalitis	encephalitis	JJ
cord-003130-p2h8p5bm	366	15	virus	virus	NN
cord-003130-p2h8p5bm	366	16	ns5	ns5	NN
cord-003130-p2h8p5bm	366	17	associates	associate	NNS
cord-003130-p2h8p5bm	366	18	with	with	IN
cord-003130-p2h8p5bm	366	19	membrane	membrane	NN
cord-003130-p2h8p5bm	366	20	protein	protein	NN
cord-003130-p2h8p5bm	366	21	scribble	scribble	NN
cord-003130-p2h8p5bm	366	22	and	and	CC
cord-003130-p2h8p5bm	366	23	impairs	impair	VBZ
cord-003130-p2h8p5bm	366	24	interferon	interferon	NN
cord-003130-p2h8p5bm	366	25	-	-	HYPH
cord-003130-p2h8p5bm	366	26	stimulated	stimulate	VBN
cord-003130-p2h8p5bm	366	27	jak	jak	NNP
cord-003130-p2h8p5bm	366	28	-	-	HYPH
cord-003130-p2h8p5bm	366	29	stat	stat	NN
cord-003130-p2h8p5bm	366	30	signalling	signal	VBG
cord-003130-p2h8p5bm	366	31	The	the	DT
cord-003130-p2h8p5bm	366	32	many	many	JJ
cord-003130-p2h8p5bm	366	33	faces	face	NNS
cord-003130-p2h8p5bm	366	34	of	of	IN
cord-003130-p2h8p5bm	366	35	the	the	DT
cord-003130-p2h8p5bm	366	36	flavivirus	flavivirus	JJ
cord-003130-p2h8p5bm	366	37	NS5	ns5	JJ
cord-003130-p2h8p5bm	366	38	protein	protein	NN
cord-003130-p2h8p5bm	366	39	in	in	IN
cord-003130-p2h8p5bm	366	40	antagonism	antagonism	NN
cord-003130-p2h8p5bm	366	41	of	of	IN
cord-003130-p2h8p5bm	366	42	type	type	NN
cord-003130-p2h8p5bm	367	1	I	-PRON-	PRP
cord-003130-p2h8p5bm	367	2	interferon	interferon	RB
cord-003130-p2h8p5bm	367	3	signaling	signal	VBG
cord-003130-p2h8p5bm	367	4	The	the	DT
cord-003130-p2h8p5bm	367	5	generation	generation	NN
cord-003130-p2h8p5bm	367	6	of	of	IN
cord-003130-p2h8p5bm	367	7	a	a	DT
cord-003130-p2h8p5bm	367	8	reverse	reverse	JJ
cord-003130-p2h8p5bm	367	9	genetics	genetics	NN
cord-003130-p2h8p5bm	367	10	system	system	NN
cord-003130-p2h8p5bm	367	11	for	for	IN
cord-003130-p2h8p5bm	367	12	kyasanur	kyasanur	NNP
cord-003130-p2h8p5bm	367	13	forest	forest	NNP
cord-003130-p2h8p5bm	367	14	disease	disease	NNP
cord-003130-p2h8p5bm	367	15	virus	virus	NN
cord-003130-p2h8p5bm	367	16	and	and	CC
cord-003130-p2h8p5bm	367	17	the	the	DT
cord-003130-p2h8p5bm	367	18	ability	ability	NN
cord-003130-p2h8p5bm	367	19	to	to	TO
cord-003130-p2h8p5bm	367	20	antagonize	antagonize	VB
cord-003130-p2h8p5bm	367	21	the	the	DT
cord-003130-p2h8p5bm	367	22	induction	induction	NN
cord-003130-p2h8p5bm	367	23	of	of	IN
cord-003130-p2h8p5bm	367	24	the	the	DT
cord-003130-p2h8p5bm	367	25	antiviral	antiviral	JJ
cord-003130-p2h8p5bm	367	26	state	state	NN
cord-003130-p2h8p5bm	367	27	in	in	IN
cord-003130-p2h8p5bm	367	28	vitro	vitro	FW
cord-003130-p2h8p5bm	367	29	Identification	identification	NN
cord-003130-p2h8p5bm	367	30	of	of	IN
cord-003130-p2h8p5bm	367	31	residues	residue	NNS
cord-003130-p2h8p5bm	367	32	critical	critical	JJ
cord-003130-p2h8p5bm	367	33	for	for	IN
cord-003130-p2h8p5bm	367	34	the	the	DT
cord-003130-p2h8p5bm	367	35	interferon	interferon	NN
cord-003130-p2h8p5bm	367	36	antagonist	antagonist	NN
cord-003130-p2h8p5bm	367	37	function	function	NN
cord-003130-p2h8p5bm	367	38	of	of	IN
cord-003130-p2h8p5bm	367	39	langat	langat	NNP
cord-003130-p2h8p5bm	367	40	virus	virus	NN
cord-003130-p2h8p5bm	368	1	ns5	ns5	NNP
cord-003130-p2h8p5bm	368	2	reveals	reveal	VBZ
cord-003130-p2h8p5bm	368	3	a	a	DT
cord-003130-p2h8p5bm	368	4	role	role	NN
cord-003130-p2h8p5bm	368	5	for	for	IN
cord-003130-p2h8p5bm	368	6	the	the	DT
cord-003130-p2h8p5bm	368	7	RNA	RNA	NNP
cord-003130-p2h8p5bm	368	8	-	-	HYPH
cord-003130-p2h8p5bm	368	9	dependent	dependent	JJ
cord-003130-p2h8p5bm	368	10	RNA	RNA	NNP
cord-003130-p2h8p5bm	368	11	polymerase	polymerase	NN
cord-003130-p2h8p5bm	368	12	domain	domain	NN
cord-003130-p2h8p5bm	368	13	Flavivirus	Flavivirus	NNP
cord-003130-p2h8p5bm	368	14	antagonism	antagonism	NN
cord-003130-p2h8p5bm	368	15	of	of	IN
cord-003130-p2h8p5bm	368	16	type	type	NN
cord-003130-p2h8p5bm	369	1	I	-PRON-	PRP
cord-003130-p2h8p5bm	369	2	interferon	interferon	VBP
cord-003130-p2h8p5bm	369	3	signaling	signal	VBG
cord-003130-p2h8p5bm	369	4	reveals	reveal	VBZ
cord-003130-p2h8p5bm	369	5	prolidase	prolidase	NN
cord-003130-p2h8p5bm	369	6	as	as	IN
cord-003130-p2h8p5bm	369	7	a	a	DT
cord-003130-p2h8p5bm	369	8	regulator	regulator	NN
cord-003130-p2h8p5bm	369	9	of	of	IN
cord-003130-p2h8p5bm	369	10	ifnar1	ifnar1	NN
cord-003130-p2h8p5bm	369	11	surface	surface	NN
cord-003130-p2h8p5bm	369	12	expression	expression	NN
cord-003130-p2h8p5bm	369	13	Limited	limited	JJ
cord-003130-p2h8p5bm	369	14	effects	effect	NNS
cord-003130-p2h8p5bm	369	15	of	of	IN
cord-003130-p2h8p5bm	369	16	type	type	NN
cord-003130-p2h8p5bm	370	1	I	-PRON-	PRP
cord-003130-p2h8p5bm	370	2	interferons	interferon	NNS
cord-003130-p2h8p5bm	370	3	on	on	IN
cord-003130-p2h8p5bm	370	4	kyasanur	kyasanur	NNP
cord-003130-p2h8p5bm	370	5	forest	forest	NNP
cord-003130-p2h8p5bm	370	6	disease	disease	NNP
cord-003130-p2h8p5bm	370	7	virus	virus	NN
cord-003130-p2h8p5bm	370	8	in	in	IN
cord-003130-p2h8p5bm	370	9	cell	cell	NN
cord-003130-p2h8p5bm	370	10	culture	culture	NN
cord-003130-p2h8p5bm	371	1	A	a	DT
cord-003130-p2h8p5bm	371	2	highly	highly	RB
cord-003130-p2h8p5bm	371	3	structured	structured	JJ
cord-003130-p2h8p5bm	371	4	,	,	,
cord-003130-p2h8p5bm	371	5	nuclease	nuclease	NN
cord-003130-p2h8p5bm	371	6	-	-	HYPH
cord-003130-p2h8p5bm	371	7	resistant	resistant	JJ
cord-003130-p2h8p5bm	371	8	,	,	,
cord-003130-p2h8p5bm	371	9	noncoding	noncoding	JJ
cord-003130-p2h8p5bm	371	10	RNA	RNA	NNP
cord-003130-p2h8p5bm	371	11	produced	produce	VBN
cord-003130-p2h8p5bm	371	12	by	by	IN
cord-003130-p2h8p5bm	371	13	flaviviruses	flavivirus	NNS
cord-003130-p2h8p5bm	371	14	is	be	VBZ
cord-003130-p2h8p5bm	371	15	required	require	VBN
cord-003130-p2h8p5bm	371	16	for	for	IN
cord-003130-p2h8p5bm	371	17	pathogenicity	pathogenicity	NN
cord-003130-p2h8p5bm	371	18	Noncoding	Noncoding	NNP
cord-003130-p2h8p5bm	371	19	subgenomic	subgenomic	NNP
cord-003130-p2h8p5bm	371	20	flavivirus	flavivirus	NNP
cord-003130-p2h8p5bm	371	21	RNA	RNA	NNP
cord-003130-p2h8p5bm	371	22	:	:	:
cord-003130-p2h8p5bm	372	1	Multiple	multiple	JJ
cord-003130-p2h8p5bm	372	2	functions	function	NNS
cord-003130-p2h8p5bm	372	3	in	in	IN
cord-003130-p2h8p5bm	372	4	west	west	NNP
cord-003130-p2h8p5bm	372	5	nile	nile	NNP
cord-003130-p2h8p5bm	372	6	virus	virus	NN
cord-003130-p2h8p5bm	372	7	pathogenesis	pathogenesis	NN
cord-003130-p2h8p5bm	372	8	and	and	CC
cord-003130-p2h8p5bm	372	9	modulation	modulation	NN
cord-003130-p2h8p5bm	372	10	of	of	IN
cord-003130-p2h8p5bm	372	11	host	host	NN
cord-003130-p2h8p5bm	372	12	responses	response	NNS
cord-003130-p2h8p5bm	372	13	Dengue	Dengue	NNP
cord-003130-p2h8p5bm	372	14	subgenomic	subgenomic	NNP
cord-003130-p2h8p5bm	372	15	RNA	RNA	NNP
cord-003130-p2h8p5bm	372	16	binds	bind	VBZ
cord-003130-p2h8p5bm	372	17	trim25	trim25	NN
cord-003130-p2h8p5bm	372	18	to	to	TO
cord-003130-p2h8p5bm	372	19	inhibit	inhibit	VB
cord-003130-p2h8p5bm	372	20	interferon	interferon	JJ
cord-003130-p2h8p5bm	372	21	expression	expression	NN
cord-003130-p2h8p5bm	372	22	for	for	IN
cord-003130-p2h8p5bm	373	1	epidemiological	epidemiological	JJ
cord-003130-p2h8p5bm	373	2	fitness	fitness	NNP
cord-003130-p2h8p5bm	373	3	Noncoding	Noncoding	NNP
cord-003130-p2h8p5bm	373	4	flavivirus	flavivirus	NNP
cord-003130-p2h8p5bm	373	5	rna	rna	NNP
cord-003130-p2h8p5bm	373	6	displays	display	VBZ
cord-003130-p2h8p5bm	373	7	RNA	RNA	NNP
cord-003130-p2h8p5bm	373	8	interference	interference	NN
cord-003130-p2h8p5bm	373	9	suppressor	suppressor	NN
cord-003130-p2h8p5bm	373	10	activity	activity	NN
cord-003130-p2h8p5bm	373	11	in	in	IN
cord-003130-p2h8p5bm	373	12	insect	insect	NN
cord-003130-p2h8p5bm	373	13	and	and	CC
cord-003130-p2h8p5bm	373	14	mammalian	mammalian	JJ
cord-003130-p2h8p5bm	373	15	cells	cell	NNS
cord-003130-p2h8p5bm	374	1	We	-PRON-	PRP
cord-003130-p2h8p5bm	374	2	would	would	MD
cord-003130-p2h8p5bm	374	3	like	like	VB
cord-003130-p2h8p5bm	374	4	to	to	TO
cord-003130-p2h8p5bm	374	5	acknowledge	acknowledge	VB
cord-003130-p2h8p5bm	374	6	Yong	Yong	NNP
cord-003130-p2h8p5bm	374	7	-	-	HYPH
cord-003130-p2h8p5bm	374	8	Dae	Dae	NNP
cord-003130-p2h8p5bm	374	9	Gwon	Gwon	NNP
cord-003130-p2h8p5bm	374	10	for	for	IN
cord-003130-p2h8p5bm	374	11	constructing	construct	VBG
cord-003130-p2h8p5bm	374	12	Figure	figure	NN
cord-003130-p2h8p5bm	374	13	1	1	CD
cord-003130-p2h8p5bm	374	14	,	,	,
cord-003130-p2h8p5bm	374	15	and	and	CC
cord-003130-p2h8p5bm	374	16	Harry	Harry	NNP
cord-003130-p2h8p5bm	374	17	Tracy	Tracy	NNP
cord-003130-p2h8p5bm	374	18	for	for	IN
cord-003130-p2h8p5bm	374	19	critically	critically	RB
cord-003130-p2h8p5bm	374	20	reading	read	VBG
cord-003130-p2h8p5bm	374	21	the	the	DT
cord-003130-p2h8p5bm	374	22	final	final	JJ
cord-003130-p2h8p5bm	374	23	version	version	NN
cord-003130-p2h8p5bm	374	24	of	of	IN
cord-003130-p2h8p5bm	374	25	the	the	DT
cord-003130-p2h8p5bm	374	26	manuscript	manuscript	NN
cord-003130-p2h8p5bm	374	27	.	.	.
cord-003130-p2h8p5bm	375	1	The	the	DT
cord-003130-p2h8p5bm	375	2	authors	author	NNS
cord-003130-p2h8p5bm	375	3	declare	declare	VBP
cord-003130-p2h8p5bm	375	4	no	no	DT
cord-003130-p2h8p5bm	375	5	conflict	conflict	NN
cord-003130-p2h8p5bm	375	6	of	of	IN
cord-003130-p2h8p5bm	375	7	interest	interest	NN
cord-003130-p2h8p5bm	375	8	.	.	.