id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-344798-q34j4zxu	Villalba, María Caridad Montalvo	Interferon gamma, TGF-β1 and RANTES expression in upper airway samples from SARS-CoV-2 infected patients	2020-08-29		.txt	text/plain	4141	232	44	title: Interferon gamma, TGF-β1 and RANTES expression in upper airway samples from SARS-CoV-2 infected patients The aim of this study was evaluate inflammatory response using the expression of immune mediators with antiviral, immunosuppression and chemotactic functions in the primary site of SARS-CoV-2 replication, at early stage of infection. J o u r n a l P r e -p r o o f Taking into account that Ct value has a correlation with the amount of RNA present in the samples, it was found that medians and IQR of SARS-CoV-2 viral titer was similar in asymptomatic (33.00, 29.00-37.00) and symptomatic (30, 27 .00-37.00) cases; and comparison between groups did not show difference (p=0.4373). As show our results, SARS-CoV-2 infection induced high IFN-γ expression in swabbed cells from upper airway; its expression was higher in symptomatic patients in comparison with asymptomatic individuals. Also, positive correlation between IFN-γ and TGF-β1 provided evidence of immune response control could determinate the asymptomatic presentation of SARS-CoV-2 infection.	./cache/cord-344798-q34j4zxu.txt	./txt/cord-344798-q34j4zxu.txt