id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-325989-nf6ouaq3	Es-Saad, Salwa	Regulators of innate immunity as novel targets for panviral therapeutics	2012-09-24		.txt	text/plain	3731	201	34	The successes obtained with Toll-like receptor (TLR) agonists in activating immune cells and as adjuvant for prophylactic vaccines against different viruses paved the way to targeted immunomodulatory therapy. The successes obtained with Toll-like receptor (TLR) agonists in activating immune cells and as adjuvant for prophylactic vaccines against different viruses paved the way to targeted immunomodulatory therapy. Better characterization of pathogen-induced immune disorders and newly discovered regulators of innate immunity have now the potential to specifically withdraw prevailing subversion mechanisms and to transform antiviral treatments by introducing panviral therapeutics with less adverse effects than IFN therapies. In the near future, targeting specific regulators of PRR-mediated innate response to withdraw viral subversion mechanisms, and access to novel surrogate measurable effector markers, hold the promise of new panviral therapeutics that will minimize adverse effects associated with type I IFN therapy.	./cache/cord-325989-nf6ouaq3.txt	./txt/cord-325989-nf6ouaq3.txt