id author title date pages extension mime words sentences flesch summary cache txt cord-307333-n6jc0jy3 Selvaggi, Carla Interferon lambda 1–3 expression in infants hospitalized for RSV or HRV associated bronchiolitis 2014-01-02 .txt text/plain 6120 304 49 OBJECTIVES: The airway expression of type III interferons (IFNs) was evaluated in infants hospitalized for respiratory syncytial virus (RSV) or rhinovirus (HRV) bronchiolitis. KEYWORDS IFN lambda; IL-28; IL-29; RSV; HRV; MxA; ISG56; Viral load; Bronchiolitis Summary Objectives: The airway expression of type III interferons (IFNs) was evaluated in infants hospitalized for respiratory syncytial virus (RSV) or rhinovirus (HRV) bronchiolitis. Therefore, we evaluated whether there was a difference in the gene expression of IFN lambda 1e3 subtypes between infants with a clinical diagnosis of RSV associated acute bronchiolitis and those with HRV infection. Results demonstrated that in cells collected from nasopharyngeal washings of RSV positive infants there are higher mRNA levels of type III IFNs compared to those observed in infants with Figure 1 Gene expression of IFN lambda 1e3 during RSV or HRV bronchiolitis. ./cache/cord-307333-n6jc0jy3.txt ./txt/cord-307333-n6jc0jy3.txt