id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-295781-b831y105	VanLeuven, James T.	Lung epithelial cells have virus-specific and shared gene expression responses to infection by diverse respiratory viruses	2017-06-02		.txt	text/plain	7213	363	52	title: Lung epithelial cells have virus-specific and shared gene expression responses to infection by diverse respiratory viruses We used microarray analysis to compare changes in gene expression of murine lung epithelial cells infected individually by three respiratory viruses causing mild (rhinovirus, RV1B), moderate (coronavirus, MHV-1), and severe (influenza A virus, PR8) disease in mice. While these models are invaluable for evaluating pathology and host responses to infection, parallel in vitro studies can be used to identify gene expression and signaling pathway changes that occur in infected cells to mediate pathogenesis. In this study, we compare the gene expression response of murine lung epithelial cells to infection by three respiratory viruses used in murine models: rhinovirus (serotype RV1B) in the family Picornaviridae, mouse hepatitis virus (MHV strain 1) in the family Coronaviridae, and influenza A virus (strain PR8) in the family Orthomyxoviridae.	./cache/cord-295781-b831y105.txt	./txt/cord-295781-b831y105.txt