id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-295684-d3p9nbgq	Lasfar, Ahmed	Interferon Lambda: A New Sword in Cancer Immunotherapy	2011-12-06		.txt	text/plain	7850	390	49	Experiments showed that similar to their human counterparts, mIFN-λ2 and mIFN-λ3 signal through the IFN-λ receptor complex, activate ISGF3, and are capable of inducing antiviral protection and MHC class I antigen expression in several cell types. IFN-α immunoregulatory functions include major histocompatibility complex (MHC) class I expression in normal and tumor cells, activation of NK cells, dendritic cells (DCs), and macrophages, resulting in the promotion of adaptive immune responses against tumors and virally infected cells [19, 20] . The secretion of constant amounts of various cytokines by transduced tumor cells at the site of tumor growth could elicit more To investigate the potential antitumoral role of IFNλ, we first evaluated the response of B16 melanoma cells to IFN-λ, by analyzing STAT1 activation and MHC class I antigen expression.	./cache/cord-295684-d3p9nbgq.txt	./txt/cord-295684-d3p9nbgq.txt