id author title date pages extension mime words sentences flesch summary cache txt cord-292289-amzzdh3t Mochizuki, M. Inhibitory effects of recombinant feline interferon on the replication of feline enteropathogenic viruses in vitro 1994-03-31 .txt text/plain 3226 158 57 Compared with each virus control culture of fcwf-4 cells, yields of rotavirus, feline panleukopenia virus (FPLV), feline calicivirus and feline infectious peritonitis coronavirus were reduced by ranges of 1.3 to ⩽3.1 log10, 0.6 log2, 0.8 to 3.7 log10 and 0.5 to 0.6 log10, respectively, in the cultures continuously treated with 10 to 10000 U of the rFeIFN. Preformed monolayers of fcwf-4, CRFK or MDCK cells in 24-well cell culture plates (Coming, New York) were treated with the rFelFN at 37°C for 24 h before challenge of VSV, FHV, rotavirus, FIPV and FCV. (2) FPLV Growth of the TU 1 strain in both fcwf-4 and CRFK cell cultures was slightly but IFN dose-dependently inhibited when the cells were continuously treated with the rFelFN for 96 h (Table 1) . The results indicate that certain degrees of antiviral effects against rotavirus, FIPV, FCV and FPLV can be generated in the feline cells by treatment with the rFelFN. ./cache/cord-292289-amzzdh3t.txt ./txt/cord-292289-amzzdh3t.txt