id author title date pages extension mime words sentences flesch summary cache txt cord-285744-jpw8hen9 Byeon, Jung Hye Comparison of cytokine responses in nasopharyngeal aspirates from children with viral lower respiratory tract infections 2009-01-13 .txt text/plain 3314 179 46 Aim: To determine whether nasopharyngeal aspirates (NPAs) cytokine response is different according to the causative viruses in children with lower respiratory tract infections (LRTI). Several studies (1-3) have investigated cytokine profiles in nasopharyngeal aspirates (NPAs) during viral lower respiratory tract infections (LRTI) in children. Previous studies (1, 3) were demonstrated that patients with respiratory syncytial virus (RSV) infection and those with influenza virus infection induce different cytokine profiles. The present study was performed to determine whether clinical responses in children with LRTI would differ according to causative viruses and to examine the differential patterns of IL-4, IL-5 and IFN-γ concentrations in NPA during acute viral lower respiratory infections according to the causative organisms. The present study of viral LRTI children indicated that as seen in NPAs local inflammatory cytokine responses differed according to the causative organisms. ./cache/cord-285744-jpw8hen9.txt ./txt/cord-285744-jpw8hen9.txt