id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-268419-j90daoiq	Resende, Lucilene Aparecida	Cytokine and nitric oxide patterns in dogs immunized with LBSap vaccine, before and after experimental challenge with Leishmania chagasi plus saliva of Lutzomyia longipalpis	2013-12-06		.txt	text/plain	7182	349	53	chagasi challenge infection, PBMCs from LBSap vaccinated dogs produced more IL-12, IFN-γ and concomitant nitric oxide (NO) when stimulated with Leishmania antigens as compared to PBMCs from respective control groups (saponin, LBtreated, or non-treated control dogs). chagasi challenge infection, PBMCs from LBSap vaccinated dogs produced more IL-12, IFN-␥ and concomitant nitric oxide (NO) when stimulated with Leishmania antigens as compared to PBMCs from respective control groups (saponin, LB-treated, or non-treated control dogs). Thus, the profile of different cytokines (IL-4, IL-10, TGF-␤, IL-12, IFN-␥, and tumor necrosis factor [TNF]-␣) and nitric oxide (NO) in supernatants of peripheral blood mononuclear cell (PBMC) cultures were evaluated before the first immunization (T 0 ), 15 days after completion of the vaccine protocol (T 3 ), and at time points 90 (T 90 ) and 885 (T 885 ) days after experimental L.	./cache/cord-268419-j90daoiq.txt	./txt/cord-268419-j90daoiq.txt