id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-048489-ajafw966	Bozza, Fernando A	Multiplex cytokine profile from dengue patients: MIP-1beta and IFN-gamma as predictive factors for severity	2008-06-25		.txt	text/plain	4936	261	45	title: Multiplex cytokine profile from dengue patients: MIP-1beta and IFN-gamma as predictive factors for severity RESULTS: IL-1β, IFN-γ, IL-4, IL-6, IL-13, IL-7 and GM-CSF were significantly increased in patients with severe clinical manifestations (severe dengue) when compared to mild disease forms (mild dengue). Analysis of factors independently associated with dengue severity and other clinical manifestations was performed with GLM with logistic regression or Gaussian family. In order to avoid effects due to differences in the blood collection time, we compared mild and severe dengue patient groups using Mann-Whitney U Test, which showed no differences in the disease onset time at the moment of sample collection [see Additional file 1]. We studied the cytokine profile from Brazilian patients in order to compare severe and mild dengue cases during the acute phase of the disease. In the present study, the use of a multiplex analysis for cytokine plasma detection in patients with dengue could identify cytokine profiles associated with the disease severity.	./cache/cord-048489-ajafw966.txt	./txt/cord-048489-ajafw966.txt