id	sid	tid	token	lemma	pos
cord-017772-zpf1xjqi	1	1	key	key	JJ
cord-017772-zpf1xjqi	2	1	:	:	:
cord-017772-zpf1xjqi	2	2	cord-017772-zpf1xjqi	cord-017772-zpf1xjqi	NNP
cord-017772-zpf1xjqi	2	3	authors	author	NNS
cord-017772-zpf1xjqi	2	4	:	:	:
cord-017772-zpf1xjqi	3	1	Walter	Walter	NNP
cord-017772-zpf1xjqi	3	2	,	,	,
cord-017772-zpf1xjqi	3	3	James	James	NNP
cord-017772-zpf1xjqi	3	4	M.	M.	NNP
cord-017772-zpf1xjqi	3	5	title	title	NN
cord-017772-zpf1xjqi	3	6	:	:	:
cord-017772-zpf1xjqi	3	7	Thrombocytopenia	Thrombocytopenia	NNP
cord-017772-zpf1xjqi	3	8	in	in	IN
cord-017772-zpf1xjqi	3	9	the	the	DT
cord-017772-zpf1xjqi	3	10	Intensive	Intensive	NNP
cord-017772-zpf1xjqi	3	11	Care	Care	NNP
cord-017772-zpf1xjqi	3	12	Unit	Unit	NNP
cord-017772-zpf1xjqi	3	13	date	date	NN
cord-017772-zpf1xjqi	3	14	:	:	:
cord-017772-zpf1xjqi	3	15	2019	2019	CD
cord-017772-zpf1xjqi	3	16	-	-	HYPH
cord-017772-zpf1xjqi	3	17	07	07	CD
cord-017772-zpf1xjqi	3	18	-	-	HYPH
cord-017772-zpf1xjqi	3	19	24	24	CD
cord-017772-zpf1xjqi	3	20	journal	journal	NN
cord-017772-zpf1xjqi	3	21	:	:	:
cord-017772-zpf1xjqi	4	1	Evidence	evidence	NN
cord-017772-zpf1xjqi	4	2	-	-	HYPH
cord-017772-zpf1xjqi	4	3	Based	base	VBN
cord-017772-zpf1xjqi	4	4	Critical	Critical	NNP
cord-017772-zpf1xjqi	4	5	Care	care	NN
cord-017772-zpf1xjqi	4	6	DOI	doi	NN
cord-017772-zpf1xjqi	4	7	:	:	:
cord-017772-zpf1xjqi	5	1	10.1007/978	10.1007/978	LS
cord-017772-zpf1xjqi	5	2	-	-	SYM
cord-017772-zpf1xjqi	5	3	3	3	CD
cord-017772-zpf1xjqi	5	4	-	-	HYPH
cord-017772-zpf1xjqi	5	5	030	030	CD
cord-017772-zpf1xjqi	5	6	-	-	HYPH
cord-017772-zpf1xjqi	5	7	26710	26710	CD
cord-017772-zpf1xjqi	5	8	-	-	HYPH
cord-017772-zpf1xjqi	5	9	0_83	0_83	CD
cord-017772-zpf1xjqi	5	10	sha	sha	NNP
cord-017772-zpf1xjqi	5	11	:	:	:
cord-017772-zpf1xjqi	5	12	0ff4ee76f47e65ced1ef95794d2bf462b069caab	0ff4ee76f47e65ced1ef95794d2bf462b069caab	CD
cord-017772-zpf1xjqi	5	13	doc_id	doc_id	CD
cord-017772-zpf1xjqi	5	14	:	:	:
cord-017772-zpf1xjqi	5	15	17772	17772	CD
cord-017772-zpf1xjqi	5	16	cord_uid	cord_uid	NNS
cord-017772-zpf1xjqi	5	17	:	:	:
cord-017772-zpf1xjqi	5	18	zpf1xjqi	zpf1xjqi	ADD
cord-017772-zpf1xjqi	6	1	The	the	DT
cord-017772-zpf1xjqi	6	2	evaluation	evaluation	NN
cord-017772-zpf1xjqi	6	3	and	and	CC
cord-017772-zpf1xjqi	6	4	management	management	NN
cord-017772-zpf1xjqi	6	5	of	of	IN
cord-017772-zpf1xjqi	6	6	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	6	7	is	be	VBZ
cord-017772-zpf1xjqi	6	8	a	a	DT
cord-017772-zpf1xjqi	6	9	daily	daily	JJ
cord-017772-zpf1xjqi	6	10	challenge	challenge	NN
cord-017772-zpf1xjqi	6	11	for	for	IN
cord-017772-zpf1xjqi	6	12	clinicians	clinician	NNS
cord-017772-zpf1xjqi	6	13	in	in	IN
cord-017772-zpf1xjqi	6	14	the	the	DT
cord-017772-zpf1xjqi	6	15	intensive	intensive	JJ
cord-017772-zpf1xjqi	6	16	care	care	NN
cord-017772-zpf1xjqi	6	17	unit	unit	NN
cord-017772-zpf1xjqi	6	18	(	(	-LRB-
cord-017772-zpf1xjqi	6	19	ICU	ICU	NNP
cord-017772-zpf1xjqi	6	20	)	)	-RRB-
cord-017772-zpf1xjqi	6	21	.	.	.
cord-017772-zpf1xjqi	7	1	Thrombocytopenia	Thrombocytopenia	NNP
cord-017772-zpf1xjqi	7	2	is	be	VBZ
cord-017772-zpf1xjqi	7	3	incredibly	incredibly	RB
cord-017772-zpf1xjqi	7	4	common	common	JJ
cord-017772-zpf1xjqi	7	5	,	,	,
cord-017772-zpf1xjqi	7	6	present	present	JJ
cord-017772-zpf1xjqi	7	7	in	in	IN
cord-017772-zpf1xjqi	7	8	upwards	upwards	RB
cord-017772-zpf1xjqi	7	9	of	of	IN
cord-017772-zpf1xjqi	7	10	60	60	CD
cord-017772-zpf1xjqi	7	11	%	%	NN
cord-017772-zpf1xjqi	7	12	of	of	IN
cord-017772-zpf1xjqi	7	13	ICU	ICU	NNP
cord-017772-zpf1xjqi	7	14	patients	patient	NNS
cord-017772-zpf1xjqi	7	15	.	.	.
cord-017772-zpf1xjqi	8	1	Additionally	additionally	RB
cord-017772-zpf1xjqi	8	2	,	,	,
cord-017772-zpf1xjqi	8	3	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	8	4	in	in	IN
cord-017772-zpf1xjqi	8	5	the	the	DT
cord-017772-zpf1xjqi	8	6	critically	critically	RB
cord-017772-zpf1xjqi	8	7	ill	ill	JJ
cord-017772-zpf1xjqi	8	8	is	be	VBZ
cord-017772-zpf1xjqi	8	9	rarely	rarely	RB
cord-017772-zpf1xjqi	8	10	caused	cause	VBN
cord-017772-zpf1xjqi	8	11	by	by	IN
cord-017772-zpf1xjqi	8	12	a	a	DT
cord-017772-zpf1xjqi	8	13	single	single	JJ
cord-017772-zpf1xjqi	8	14	etiology	etiology	NN
cord-017772-zpf1xjqi	8	15	.	.	.
cord-017772-zpf1xjqi	9	1	Several	several	JJ
cord-017772-zpf1xjqi	9	2	causes	cause	NNS
cord-017772-zpf1xjqi	9	3	of	of	IN
cord-017772-zpf1xjqi	9	4	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	9	5	in	in	IN
cord-017772-zpf1xjqi	9	6	the	the	DT
cord-017772-zpf1xjqi	9	7	ICU	ICU	NNP
cord-017772-zpf1xjqi	9	8	including	include	VBG
cord-017772-zpf1xjqi	9	9	heparin	heparin	NN
cord-017772-zpf1xjqi	9	10	-	-	HYPH
cord-017772-zpf1xjqi	9	11	induced	induce	VBN
cord-017772-zpf1xjqi	9	12	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	9	13	(	(	-LRB-
cord-017772-zpf1xjqi	9	14	HIT	hit	VB
cord-017772-zpf1xjqi	9	15	)	)	-RRB-
cord-017772-zpf1xjqi	9	16	and	and	CC
cord-017772-zpf1xjqi	9	17	thrombotic	thrombotic	JJ
cord-017772-zpf1xjqi	9	18	thrombocytopenic	thrombocytopenic	JJ
cord-017772-zpf1xjqi	9	19	purpura	purpura	NN
cord-017772-zpf1xjqi	9	20	demand	demand	VBP
cord-017772-zpf1xjqi	9	21	urgent	urgent	JJ
cord-017772-zpf1xjqi	9	22	recognition	recognition	NN
cord-017772-zpf1xjqi	9	23	and	and	CC
cord-017772-zpf1xjqi	9	24	intervention	intervention	NN
cord-017772-zpf1xjqi	9	25	.	.	.
cord-017772-zpf1xjqi	10	1	This	this	DT
cord-017772-zpf1xjqi	10	2	chapter	chapter	NN
cord-017772-zpf1xjqi	10	3	provides	provide	VBZ
cord-017772-zpf1xjqi	10	4	a	a	DT
cord-017772-zpf1xjqi	10	5	general	general	JJ
cord-017772-zpf1xjqi	10	6	overview	overview	NN
cord-017772-zpf1xjqi	10	7	of	of	IN
cord-017772-zpf1xjqi	10	8	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	10	9	in	in	IN
cord-017772-zpf1xjqi	10	10	the	the	DT
cord-017772-zpf1xjqi	10	11	ICU	ICU	NNP
cord-017772-zpf1xjqi	10	12	and	and	CC
cord-017772-zpf1xjqi	10	13	highlights	highlight	VBZ
cord-017772-zpf1xjqi	10	14	important	important	JJ
cord-017772-zpf1xjqi	10	15	diagnostic	diagnostic	JJ
cord-017772-zpf1xjqi	10	16	and	and	CC
cord-017772-zpf1xjqi	10	17	management	management	NN
cord-017772-zpf1xjqi	10	18	considerations	consideration	NNS
cord-017772-zpf1xjqi	10	19	for	for	IN
cord-017772-zpf1xjqi	10	20	some	some	DT
cord-017772-zpf1xjqi	10	21	of	of	IN
cord-017772-zpf1xjqi	10	22	the	the	DT
cord-017772-zpf1xjqi	10	23	most	most	RBS
cord-017772-zpf1xjqi	10	24	common	common	JJ
cord-017772-zpf1xjqi	10	25	etiologies	etiology	NNS
cord-017772-zpf1xjqi	10	26	.	.	.
cord-017772-zpf1xjqi	11	1	point	point	NN
cord-017772-zpf1xjqi	11	2	during	during	IN
cord-017772-zpf1xjqi	11	3	their	-PRON-	PRP$
cord-017772-zpf1xjqi	11	4	ICU	ICU	NNP
cord-017772-zpf1xjqi	11	5	stay	stay	VBP
cord-017772-zpf1xjqi	11	6	[	[	-LRB-
cord-017772-zpf1xjqi	11	7	7	7	CD
cord-017772-zpf1xjqi	11	8	,	,	,
cord-017772-zpf1xjqi	11	9	8	8	CD
cord-017772-zpf1xjqi	11	10	,	,	,
cord-017772-zpf1xjqi	11	11	10	10	CD
cord-017772-zpf1xjqi	11	12	,	,	,
cord-017772-zpf1xjqi	11	13	11	11	CD
cord-017772-zpf1xjqi	11	14	]	]	-RRB-
cord-017772-zpf1xjqi	11	15	.	.	.
cord-017772-zpf1xjqi	12	1	In	in	IN
cord-017772-zpf1xjqi	12	2	general	general	JJ
cord-017772-zpf1xjqi	12	3	,	,	,
cord-017772-zpf1xjqi	12	4	ICU	ICU	NNP
cord-017772-zpf1xjqi	12	5	patients	patient	NNS
cord-017772-zpf1xjqi	12	6	who	who	WP
cord-017772-zpf1xjqi	12	7	develop	develop	VBP
cord-017772-zpf1xjqi	12	8	thrombocytopenia	thrombocytopenia	NNS
cord-017772-zpf1xjqi	12	9	are	be	VBP
cord-017772-zpf1xjqi	12	10	sicker	sick	JJR
cord-017772-zpf1xjqi	12	11	than	than	IN
cord-017772-zpf1xjqi	12	12	patients	patient	NNS
cord-017772-zpf1xjqi	12	13	with	with	IN
cord-017772-zpf1xjqi	12	14	normal	normal	JJ
cord-017772-zpf1xjqi	12	15	platelet	platelet	NN
cord-017772-zpf1xjqi	12	16	counts	count	NNS
cord-017772-zpf1xjqi	12	17	,	,	,
cord-017772-zpf1xjqi	12	18	with	with	IN
cord-017772-zpf1xjqi	12	19	higher	high	JJR
cord-017772-zpf1xjqi	12	20	illness	illness	NN
cord-017772-zpf1xjqi	12	21	severity	severity	NN
cord-017772-zpf1xjqi	12	22	scores	score	NNS
cord-017772-zpf1xjqi	12	23	,	,	,
cord-017772-zpf1xjqi	12	24	more	more	JJR
cord-017772-zpf1xjqi	12	25	need	need	NN
cord-017772-zpf1xjqi	12	26	for	for	IN
cord-017772-zpf1xjqi	12	27	vasoactive	vasoactive	JJ
cord-017772-zpf1xjqi	12	28	infusions	infusion	NNS
cord-017772-zpf1xjqi	12	29	,	,	,
cord-017772-zpf1xjqi	12	30	and	and	CC
cord-017772-zpf1xjqi	12	31	more	more	JJR
cord-017772-zpf1xjqi	12	32	organ	organ	NN
cord-017772-zpf1xjqi	12	33	dysfunction	dysfunction	NN
cord-017772-zpf1xjqi	12	34	[	[	-LRB-
cord-017772-zpf1xjqi	12	35	8	8	CD
cord-017772-zpf1xjqi	12	36	,	,	,
cord-017772-zpf1xjqi	12	37	9	9	CD
cord-017772-zpf1xjqi	12	38	]	]	-RRB-
cord-017772-zpf1xjqi	12	39	.	.	.
cord-017772-zpf1xjqi	13	1	The	the	DT
cord-017772-zpf1xjqi	13	2	presence	presence	NN
cord-017772-zpf1xjqi	13	3	of	of	IN
cord-017772-zpf1xjqi	13	4	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	13	5	in	in	IN
cord-017772-zpf1xjqi	13	6	the	the	DT
cord-017772-zpf1xjqi	13	7	critically	critically	RB
cord-017772-zpf1xjqi	13	8	ill	ill	JJ
cord-017772-zpf1xjqi	13	9	has	have	VBZ
cord-017772-zpf1xjqi	13	10	consistently	consistently	RB
cord-017772-zpf1xjqi	13	11	been	be	VBN
cord-017772-zpf1xjqi	13	12	associated	associate	VBN
cord-017772-zpf1xjqi	13	13	with	with	IN
cord-017772-zpf1xjqi	13	14	poor	poor	JJ
cord-017772-zpf1xjqi	13	15	outcomes	outcome	NNS
cord-017772-zpf1xjqi	13	16	.	.	.
cord-017772-zpf1xjqi	14	1	In	in	IN
cord-017772-zpf1xjqi	14	2	a	a	DT
cord-017772-zpf1xjqi	14	3	multicenter	multicenter	JJ
cord-017772-zpf1xjqi	14	4	review	review	NN
cord-017772-zpf1xjqi	14	5	of	of	IN
cord-017772-zpf1xjqi	14	6	over	over	IN
cord-017772-zpf1xjqi	14	7	3000	3000	CD
cord-017772-zpf1xjqi	14	8	critically	critically	RB
cord-017772-zpf1xjqi	14	9	ill	ill	JJ
cord-017772-zpf1xjqi	14	10	patients	patient	NNS
cord-017772-zpf1xjqi	14	11	,	,	,
cord-017772-zpf1xjqi	14	12	patients	patient	NNS
cord-017772-zpf1xjqi	14	13	with	with	IN
cord-017772-zpf1xjqi	14	14	severe	severe	JJ
cord-017772-zpf1xjqi	14	15	thrombocytopenia	thrombocytopenia	NNS
cord-017772-zpf1xjqi	14	16	(	(	-LRB-
cord-017772-zpf1xjqi	14	17	defined	define	VBN
cord-017772-zpf1xjqi	14	18	as	as	IN
cord-017772-zpf1xjqi	14	19	a	a	DT
cord-017772-zpf1xjqi	14	20	platelet	platelet	NN
cord-017772-zpf1xjqi	14	21	count	count	NN
cord-017772-zpf1xjqi	14	22	<	<	XX
cord-017772-zpf1xjqi	14	23	50	50	CD
cord-017772-zpf1xjqi	14	24	×	×	NN
cord-017772-zpf1xjqi	14	25	10	10	CD
cord-017772-zpf1xjqi	14	26	9	9	CD
cord-017772-zpf1xjqi	14	27	cells	cell	NNS
cord-017772-zpf1xjqi	14	28	/	/	SYM
cord-017772-zpf1xjqi	14	29	L	L	NNP
cord-017772-zpf1xjqi	14	30	)	)	-RRB-
cord-017772-zpf1xjqi	14	31	had	have	VBD
cord-017772-zpf1xjqi	14	32	an	an	DT
cord-017772-zpf1xjqi	14	33	adjusted	adjusted	JJ
cord-017772-zpf1xjqi	14	34	hazard	hazard	NN
cord-017772-zpf1xjqi	14	35	ratio	ratio	NN
cord-017772-zpf1xjqi	14	36	for	for	IN
cord-017772-zpf1xjqi	14	37	hospital	hospital	NN
cord-017772-zpf1xjqi	14	38	mortality	mortality	NN
cord-017772-zpf1xjqi	14	39	of	of	IN
cord-017772-zpf1xjqi	14	40	2.78	2.78	CD
cord-017772-zpf1xjqi	14	41	(	(	-LRB-
cord-017772-zpf1xjqi	14	42	95	95	CD
cord-017772-zpf1xjqi	14	43	%	%	NN
cord-017772-zpf1xjqi	14	44	CI	CI	NNP
cord-017772-zpf1xjqi	14	45	,	,	,
cord-017772-zpf1xjqi	14	46	2.20	2.20	CD
cord-017772-zpf1xjqi	14	47	-	-	SYM
cord-017772-zpf1xjqi	14	48	3.53	3.53	CD
cord-017772-zpf1xjqi	14	49	)	)	-RRB-
cord-017772-zpf1xjqi	14	50	compared	compare	VBN
cord-017772-zpf1xjqi	14	51	to	to	IN
cord-017772-zpf1xjqi	14	52	patients	patient	NNS
cord-017772-zpf1xjqi	14	53	with	with	IN
cord-017772-zpf1xjqi	14	54	normal	normal	JJ
cord-017772-zpf1xjqi	14	55	platelet	platelet	NN
cord-017772-zpf1xjqi	14	56	counts	count	NNS
cord-017772-zpf1xjqi	14	57	[	[	-LRB-
cord-017772-zpf1xjqi	14	58	8	8	CD
cord-017772-zpf1xjqi	14	59	]	]	-RRB-
cord-017772-zpf1xjqi	14	60	.	.	.
cord-017772-zpf1xjqi	15	1	The	the	DT
cord-017772-zpf1xjqi	15	2	association	association	NN
cord-017772-zpf1xjqi	15	3	between	between	IN
cord-017772-zpf1xjqi	15	4	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	15	5	and	and	CC
cord-017772-zpf1xjqi	15	6	mortality	mortality	NN
cord-017772-zpf1xjqi	15	7	has	have	VBZ
cord-017772-zpf1xjqi	15	8	been	be	VBN
cord-017772-zpf1xjqi	15	9	identified	identify	VBN
cord-017772-zpf1xjqi	15	10	in	in	IN
cord-017772-zpf1xjqi	15	11	multiple	multiple	JJ
cord-017772-zpf1xjqi	15	12	studies	study	NNS
cord-017772-zpf1xjqi	15	13	[	[	-LRB-
cord-017772-zpf1xjqi	15	14	6	6	CD
cord-017772-zpf1xjqi	15	15	,	,	,
cord-017772-zpf1xjqi	15	16	9	9	CD
cord-017772-zpf1xjqi	15	17	,	,	,
cord-017772-zpf1xjqi	15	18	10	10	CD
cord-017772-zpf1xjqi	15	19	,	,	,
cord-017772-zpf1xjqi	15	20	12	12	CD
cord-017772-zpf1xjqi	15	21	]	]	-RRB-
cord-017772-zpf1xjqi	15	22	.	.	.
cord-017772-zpf1xjqi	16	1	Regardless	regardless	RB
cord-017772-zpf1xjqi	16	2	of	of	IN
cord-017772-zpf1xjqi	16	3	the	the	DT
cord-017772-zpf1xjqi	16	4	absolute	absolute	JJ
cord-017772-zpf1xjqi	16	5	value	value	NN
cord-017772-zpf1xjqi	16	6	,	,	,
cord-017772-zpf1xjqi	16	7	a	a	DT
cord-017772-zpf1xjqi	16	8	fall	fall	NN
cord-017772-zpf1xjqi	16	9	in	in	IN
cord-017772-zpf1xjqi	16	10	platelet	platelet	NN
cord-017772-zpf1xjqi	16	11	count	count	NN
cord-017772-zpf1xjqi	16	12	by	by	IN
cord-017772-zpf1xjqi	16	13	>	>	XX
cord-017772-zpf1xjqi	16	14	30	30	CD
cord-017772-zpf1xjqi	16	15	%	%	NN
cord-017772-zpf1xjqi	16	16	from	from	IN
cord-017772-zpf1xjqi	16	17	a	a	DT
cord-017772-zpf1xjqi	16	18	patient	patient	NN
cord-017772-zpf1xjqi	16	19	's	's	POS
cord-017772-zpf1xjqi	16	20	admission	admission	NN
cord-017772-zpf1xjqi	16	21	level	level	NN
cord-017772-zpf1xjqi	16	22	identifies	identify	VBZ
cord-017772-zpf1xjqi	16	23	patients	patient	NNS
cord-017772-zpf1xjqi	16	24	who	who	WP
cord-017772-zpf1xjqi	16	25	may	may	MD
cord-017772-zpf1xjqi	16	26	be	be	VB
cord-017772-zpf1xjqi	16	27	up	up	IN
cord-017772-zpf1xjqi	16	28	to	to	TO
cord-017772-zpf1xjqi	16	29	4	4	CD
cord-017772-zpf1xjqi	16	30	times	time	NNS
cord-017772-zpf1xjqi	16	31	more	more	RBR
cord-017772-zpf1xjqi	16	32	likely	likely	JJ
cord-017772-zpf1xjqi	16	33	to	to	TO
cord-017772-zpf1xjqi	16	34	die	die	VB
cord-017772-zpf1xjqi	16	35	during	during	IN
cord-017772-zpf1xjqi	16	36	their	-PRON-	PRP$
cord-017772-zpf1xjqi	16	37	hospital	hospital	NN
cord-017772-zpf1xjqi	16	38	stay	stay	NN
cord-017772-zpf1xjqi	16	39	[	[	-LRB-
cord-017772-zpf1xjqi	16	40	11	11	CD
cord-017772-zpf1xjqi	16	41	,	,	,
cord-017772-zpf1xjqi	16	42	13	13	CD
cord-017772-zpf1xjqi	16	43	]	]	-RRB-
cord-017772-zpf1xjqi	16	44	.	.	.
cord-017772-zpf1xjqi	17	1	Patients	patient	NNS
cord-017772-zpf1xjqi	17	2	whose	whose	WP$
cord-017772-zpf1xjqi	17	3	platelet	platelet	NN
cord-017772-zpf1xjqi	17	4	count	count	NN
cord-017772-zpf1xjqi	17	5	fails	fail	VBZ
cord-017772-zpf1xjqi	17	6	to	to	TO
cord-017772-zpf1xjqi	17	7	recover	recover	VB
cord-017772-zpf1xjqi	17	8	during	during	IN
cord-017772-zpf1xjqi	17	9	their	-PRON-	PRP$
cord-017772-zpf1xjqi	17	10	ICU	ICU	NNP
cord-017772-zpf1xjqi	17	11	course	course	NN
cord-017772-zpf1xjqi	17	12	represent	represent	VBP
cord-017772-zpf1xjqi	17	13	a	a	DT
cord-017772-zpf1xjqi	17	14	particularly	particularly	RB
cord-017772-zpf1xjqi	17	15	high	high	JJ
cord-017772-zpf1xjqi	17	16	risk	risk	NN
cord-017772-zpf1xjqi	17	17	group	group	NN
cord-017772-zpf1xjqi	17	18	[	[	-LRB-
cord-017772-zpf1xjqi	17	19	6	6	CD
cord-017772-zpf1xjqi	17	20	,	,	,
cord-017772-zpf1xjqi	17	21	14	14	CD
cord-017772-zpf1xjqi	17	22	]	]	-RRB-
cord-017772-zpf1xjqi	17	23	.	.	.
cord-017772-zpf1xjqi	18	1	The	the	DT
cord-017772-zpf1xjqi	18	2	presence	presence	NN
cord-017772-zpf1xjqi	18	3	and	and	CC
cord-017772-zpf1xjqi	18	4	severity	severity	NN
cord-017772-zpf1xjqi	18	5	of	of	IN
cord-017772-zpf1xjqi	18	6	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	18	7	is	be	VBZ
cord-017772-zpf1xjqi	18	8	included	include	VBN
cord-017772-zpf1xjqi	18	9	in	in	IN
cord-017772-zpf1xjqi	18	10	several	several	JJ
cord-017772-zpf1xjqi	18	11	validated	validate	VBN
cord-017772-zpf1xjqi	18	12	severity	severity	NN
cord-017772-zpf1xjqi	18	13	scores	score	NNS
cord-017772-zpf1xjqi	18	14	including	include	VBG
cord-017772-zpf1xjqi	18	15	the	the	DT
cord-017772-zpf1xjqi	18	16	Multiple	Multiple	NNP
cord-017772-zpf1xjqi	18	17	Organ	Organ	NNP
cord-017772-zpf1xjqi	18	18	Dysfunction	Dysfunction	NNP
cord-017772-zpf1xjqi	18	19	Score	Score	NNP
cord-017772-zpf1xjqi	18	20	and	and	CC
cord-017772-zpf1xjqi	18	21	the	the	DT
cord-017772-zpf1xjqi	18	22	Sepsis	sepsis	NN
cord-017772-zpf1xjqi	18	23	-	-	HYPH
cord-017772-zpf1xjqi	18	24	related	relate	VBN
cord-017772-zpf1xjqi	18	25	Organ	Organ	NNP
cord-017772-zpf1xjqi	18	26	Failure	Failure	NNP
cord-017772-zpf1xjqi	18	27	Assessment	Assessment	NNP
cord-017772-zpf1xjqi	18	28	[	[	-LRB-
cord-017772-zpf1xjqi	18	29	15	15	CD
cord-017772-zpf1xjqi	18	30	,	,	,
cord-017772-zpf1xjqi	18	31	16	16	CD
cord-017772-zpf1xjqi	18	32	]	]	-RRB-
cord-017772-zpf1xjqi	18	33	.	.	.
cord-017772-zpf1xjqi	19	1	The	the	DT
cord-017772-zpf1xjqi	19	2	evaluation	evaluation	NN
cord-017772-zpf1xjqi	19	3	of	of	IN
cord-017772-zpf1xjqi	19	4	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	19	5	in	in	IN
cord-017772-zpf1xjqi	19	6	the	the	DT
cord-017772-zpf1xjqi	19	7	ICU	ICU	NNP
cord-017772-zpf1xjqi	19	8	is	be	VBZ
cord-017772-zpf1xjqi	19	9	challenging	challenging	JJ
cord-017772-zpf1xjqi	19	10	as	as	IN
cord-017772-zpf1xjqi	19	11	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	19	12	is	be	VBZ
cord-017772-zpf1xjqi	19	13	both	both	CC
cord-017772-zpf1xjqi	19	14	a	a	DT
cord-017772-zpf1xjqi	19	15	common	common	JJ
cord-017772-zpf1xjqi	19	16	problem	problem	NN
cord-017772-zpf1xjqi	19	17	and	and	CC
cord-017772-zpf1xjqi	19	18	rarely	rarely	RB
cord-017772-zpf1xjqi	19	19	due	due	JJ
cord-017772-zpf1xjqi	19	20	to	to	IN
cord-017772-zpf1xjqi	19	21	a	a	DT
cord-017772-zpf1xjqi	19	22	single	single	JJ
cord-017772-zpf1xjqi	19	23	etiology	etiology	NN
cord-017772-zpf1xjqi	19	24	.	.	.
cord-017772-zpf1xjqi	20	1	In	in	IN
cord-017772-zpf1xjqi	20	2	a	a	DT
cord-017772-zpf1xjqi	20	3	study	study	NN
cord-017772-zpf1xjqi	20	4	of	of	IN
cord-017772-zpf1xjqi	20	5	over	over	IN
cord-017772-zpf1xjqi	20	6	300	300	CD
cord-017772-zpf1xjqi	20	7	ICU	ICU	NNP
cord-017772-zpf1xjqi	20	8	patients	patient	NNS
cord-017772-zpf1xjqi	20	9	with	with	IN
cord-017772-zpf1xjqi	20	10	either	either	CC
cord-017772-zpf1xjqi	20	11	absolute	absolute	JJ
cord-017772-zpf1xjqi	20	12	(	(	-LRB-
cord-017772-zpf1xjqi	20	13	platelet	platelet	NN
cord-017772-zpf1xjqi	20	14	count	count	NN
cord-017772-zpf1xjqi	20	15	<	<	XX
cord-017772-zpf1xjqi	20	16	100	100	CD
cord-017772-zpf1xjqi	20	17	×	×	NN
cord-017772-zpf1xjqi	20	18	10	10	CD
cord-017772-zpf1xjqi	20	19	9	9	CD
cord-017772-zpf1xjqi	20	20	cells	cell	NNS
cord-017772-zpf1xjqi	20	21	/	/	SYM
cord-017772-zpf1xjqi	20	22	L	l	NN
cord-017772-zpf1xjqi	20	23	)	)	-RRB-
cord-017772-zpf1xjqi	20	24	or	or	CC
cord-017772-zpf1xjqi	20	25	relative	relative	JJ
cord-017772-zpf1xjqi	20	26	(	(	-LRB-
cord-017772-zpf1xjqi	20	27	decrease	decrease	NN
cord-017772-zpf1xjqi	20	28	in	in	IN
cord-017772-zpf1xjqi	20	29	platelet	platelet	NN
cord-017772-zpf1xjqi	20	30	count	count	NN
cord-017772-zpf1xjqi	20	31	>	>	XX
cord-017772-zpf1xjqi	20	32	30	30	CD
cord-017772-zpf1xjqi	20	33	%	%	NN
cord-017772-zpf1xjqi	20	34	)	)	-RRB-
cord-017772-zpf1xjqi	20	35	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	20	36	who	who	WP
cord-017772-zpf1xjqi	20	37	underwent	undergo	VBD
cord-017772-zpf1xjqi	20	38	extensive	extensive	JJ
cord-017772-zpf1xjqi	20	39	evaluation	evaluation	NN
cord-017772-zpf1xjqi	20	40	including	include	VBG
cord-017772-zpf1xjqi	20	41	bone	bone	NN
cord-017772-zpf1xjqi	20	42	marrow	marrow	NN
cord-017772-zpf1xjqi	20	43	aspiration	aspiration	NN
cord-017772-zpf1xjqi	20	44	,	,	,
cord-017772-zpf1xjqi	20	45	37	37	CD
cord-017772-zpf1xjqi	20	46	%	%	NN
cord-017772-zpf1xjqi	20	47	had	have	VBD
cord-017772-zpf1xjqi	20	48	3	3	CD
cord-017772-zpf1xjqi	20	49	or	or	CC
cord-017772-zpf1xjqi	20	50	more	more	RBR
cord-017772-zpf1xjqi	20	51	identifiable	identifiable	JJ
cord-017772-zpf1xjqi	20	52	etiologies	etiology	NNS
cord-017772-zpf1xjqi	20	53	for	for	IN
cord-017772-zpf1xjqi	20	54	their	-PRON-	PRP$
cord-017772-zpf1xjqi	20	55	thrombocytopenia	thrombocytopenia	NNS
cord-017772-zpf1xjqi	20	56	[	[	-LRB-
cord-017772-zpf1xjqi	20	57	17	17	CD
cord-017772-zpf1xjqi	20	58	]	]	-RRB-
cord-017772-zpf1xjqi	20	59	.	.	.
cord-017772-zpf1xjqi	21	1	As	as	IN
cord-017772-zpf1xjqi	21	2	such	such	JJ
cord-017772-zpf1xjqi	21	3	,	,	,
cord-017772-zpf1xjqi	21	4	a	a	DT
cord-017772-zpf1xjqi	21	5	structured	structured	JJ
cord-017772-zpf1xjqi	21	6	approach	approach	NN
cord-017772-zpf1xjqi	21	7	to	to	IN
cord-017772-zpf1xjqi	21	8	the	the	DT
cord-017772-zpf1xjqi	21	9	evaluation	evaluation	NN
cord-017772-zpf1xjqi	21	10	and	and	CC
cord-017772-zpf1xjqi	21	11	management	management	NN
cord-017772-zpf1xjqi	21	12	of	of	IN
cord-017772-zpf1xjqi	21	13	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	21	14	is	be	VBZ
cord-017772-zpf1xjqi	21	15	essential	essential	JJ
cord-017772-zpf1xjqi	21	16	.	.	.
cord-017772-zpf1xjqi	22	1	A	a	DT
cord-017772-zpf1xjqi	22	2	comprehensive	comprehensive	JJ
cord-017772-zpf1xjqi	22	3	review	review	NN
cord-017772-zpf1xjqi	22	4	of	of	IN
cord-017772-zpf1xjqi	22	5	the	the	DT
cord-017772-zpf1xjqi	22	6	myriad	myriad	JJ
cord-017772-zpf1xjqi	22	7	causes	cause	NNS
cord-017772-zpf1xjqi	22	8	of	of	IN
cord-017772-zpf1xjqi	22	9	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	22	10	is	be	VBZ
cord-017772-zpf1xjqi	22	11	beyond	beyond	IN
cord-017772-zpf1xjqi	22	12	the	the	DT
cord-017772-zpf1xjqi	22	13	scope	scope	NN
cord-017772-zpf1xjqi	22	14	of	of	IN
cord-017772-zpf1xjqi	22	15	this	this	DT
cord-017772-zpf1xjqi	22	16	review	review	NN
cord-017772-zpf1xjqi	22	17	.	.	.
cord-017772-zpf1xjqi	23	1	What	what	WP
cord-017772-zpf1xjqi	23	2	follows	follow	VBZ
cord-017772-zpf1xjqi	23	3	is	be	VBZ
cord-017772-zpf1xjqi	23	4	a	a	DT
cord-017772-zpf1xjqi	23	5	simplified	simplified	JJ
cord-017772-zpf1xjqi	23	6	approach	approach	NN
cord-017772-zpf1xjqi	23	7	to	to	IN
cord-017772-zpf1xjqi	23	8	the	the	DT
cord-017772-zpf1xjqi	23	9	critically	critically	RB
cord-017772-zpf1xjqi	23	10	ill	ill	JJ
cord-017772-zpf1xjqi	23	11	patient	patient	NN
cord-017772-zpf1xjqi	23	12	with	with	IN
cord-017772-zpf1xjqi	23	13	newonset	newonset	NNP
cord-017772-zpf1xjqi	23	14	thrombocytopenia	thrombocytopenia	NNP
cord-017772-zpf1xjqi	24	1	(	(	-LRB-
cord-017772-zpf1xjqi	24	2	Fig	Fig	NNP
cord-017772-zpf1xjqi	24	3	.	.	.
cord-017772-zpf1xjqi	24	4	83.1	83.1	CD
cord-017772-zpf1xjqi	24	5	)	)	-RRB-
cord-017772-zpf1xjqi	24	6	.	.	.
cord-017772-zpf1xjqi	25	1	Step	step	NN
cord-017772-zpf1xjqi	25	2	1	1	CD
cord-017772-zpf1xjqi	25	3	:	:	:
cord-017772-zpf1xjqi	25	4	Confirm	confirm	VB
cord-017772-zpf1xjqi	25	5	True	true	JJ
cord-017772-zpf1xjqi	25	6	Thrombocytopenia	Thrombocytopenia	NNP
cord-017772-zpf1xjqi	25	7	Pseudothrombocytopenia	Pseudothrombocytopenia	NNP
cord-017772-zpf1xjqi	26	1	Occasionally	occasionally	RB
cord-017772-zpf1xjqi	26	2	,	,	,
cord-017772-zpf1xjqi	26	3	a	a	DT
cord-017772-zpf1xjqi	26	4	low	low	JJ
cord-017772-zpf1xjqi	26	5	reported	reported	JJ
cord-017772-zpf1xjqi	26	6	platelet	platelet	NN
cord-017772-zpf1xjqi	26	7	count	count	NN
cord-017772-zpf1xjqi	26	8	does	do	VBZ
cord-017772-zpf1xjqi	26	9	not	not	RB
cord-017772-zpf1xjqi	26	10	represent	represent	VB
cord-017772-zpf1xjqi	26	11	true	true	JJ
cord-017772-zpf1xjqi	26	12	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	26	13	.	.	.
cord-017772-zpf1xjqi	27	1	Exposure	exposure	NN
cord-017772-zpf1xjqi	27	2	to	to	IN
cord-017772-zpf1xjqi	27	3	ethylenediaminetetraacetic	ethylenediaminetetraacetic	JJ
cord-017772-zpf1xjqi	27	4	acid	acid	NN
cord-017772-zpf1xjqi	27	5	(	(	-LRB-
cord-017772-zpf1xjqi	27	6	EDTA	EDTA	NNP
cord-017772-zpf1xjqi	27	7	)	)	-RRB-
cord-017772-zpf1xjqi	27	8	in	in	IN
cord-017772-zpf1xjqi	27	9	blood	blood	NN
cord-017772-zpf1xjqi	27	10	collection	collection	NN
cord-017772-zpf1xjqi	27	11	tubes	tube	NNS
cord-017772-zpf1xjqi	27	12	induces	induce	VBZ
cord-017772-zpf1xjqi	27	13	a	a	DT
cord-017772-zpf1xjqi	27	14	conformational	conformational	JJ
cord-017772-zpf1xjqi	27	15	change	change	NN
cord-017772-zpf1xjqi	27	16	in	in	IN
cord-017772-zpf1xjqi	27	17	the	the	DT
cord-017772-zpf1xjqi	27	18	platelet	platelet	NN
cord-017772-zpf1xjqi	27	19	surface	surface	NN
cord-017772-zpf1xjqi	27	20	protein	protein	NN
cord-017772-zpf1xjqi	27	21	glycoprotein	glycoprotein	NN
cord-017772-zpf1xjqi	27	22	IIb	IIb	NNP
cord-017772-zpf1xjqi	27	23	/	/	SYM
cord-017772-zpf1xjqi	27	24	IIIa	IIIa	NNS
cord-017772-zpf1xjqi	27	25	[	[	-LRB-
cord-017772-zpf1xjqi	27	26	18	18	CD
cord-017772-zpf1xjqi	27	27	]	]	-RRB-
cord-017772-zpf1xjqi	27	28	.	.	.
cord-017772-zpf1xjqi	28	1	Patients	patient	NNS
cord-017772-zpf1xjqi	28	2	may	may	MD
cord-017772-zpf1xjqi	28	3	develop	develop	VB
cord-017772-zpf1xjqi	28	4	IgM	IgM	NNP
cord-017772-zpf1xjqi	28	5	autoantibodies	autoantibody	NNS
cord-017772-zpf1xjqi	28	6	to	to	IN
cord-017772-zpf1xjqi	28	7	these	these	DT
cord-017772-zpf1xjqi	28	8	newly	newly	RB
cord-017772-zpf1xjqi	28	9	exposed	expose	VBN
cord-017772-zpf1xjqi	28	10	GIIb	GIIb	NNS
cord-017772-zpf1xjqi	28	11	/	/	SYM
cord-017772-zpf1xjqi	28	12	IIIa	IIIa	NNP
cord-017772-zpf1xjqi	28	13	epitopes	epitope	NNS
cord-017772-zpf1xjqi	28	14	which	which	WDT
cord-017772-zpf1xjqi	28	15	causes	cause	VBZ
cord-017772-zpf1xjqi	28	16	in	in	IN
cord-017772-zpf1xjqi	28	17	vitro	vitro	FW
cord-017772-zpf1xjqi	28	18	platelet	platelet	NN
cord-017772-zpf1xjqi	28	19	clumping	clumping	NN
cord-017772-zpf1xjqi	28	20	.	.	.
cord-017772-zpf1xjqi	29	1	Large	large	JJ
cord-017772-zpf1xjqi	29	2	platelet	platelet	NN
cord-017772-zpf1xjqi	29	3	aggregates	aggregate	NNS
cord-017772-zpf1xjqi	29	4	are	be	VBP
cord-017772-zpf1xjqi	29	5	not	not	RB
cord-017772-zpf1xjqi	29	6	recognized	recognize	VBN
cord-017772-zpf1xjqi	29	7	by	by	IN
cord-017772-zpf1xjqi	29	8	automated	automate	VBN
cord-017772-zpf1xjqi	29	9	counters	counter	NNS
cord-017772-zpf1xjqi	29	10	,	,	,
cord-017772-zpf1xjqi	29	11	leading	lead	VBG
cord-017772-zpf1xjqi	29	12	to	to	IN
cord-017772-zpf1xjqi	29	13	a	a	DT
cord-017772-zpf1xjqi	29	14	falsely	falsely	RB
cord-017772-zpf1xjqi	29	15	low	low	JJ
cord-017772-zpf1xjqi	29	16	reported	reported	JJ
cord-017772-zpf1xjqi	29	17	platelet	platelet	NN
cord-017772-zpf1xjqi	29	18	count	count	NN
cord-017772-zpf1xjqi	29	19	.	.	.
cord-017772-zpf1xjqi	30	1	The	the	DT
cord-017772-zpf1xjqi	30	2	identification	identification	NN
cord-017772-zpf1xjqi	30	3	of	of	IN
cord-017772-zpf1xjqi	30	4	platelet	platelet	NN
cord-017772-zpf1xjqi	30	5	clumps	clump	NNS
cord-017772-zpf1xjqi	30	6	on	on	IN
cord-017772-zpf1xjqi	30	7	a	a	DT
cord-017772-zpf1xjqi	30	8	peripheral	peripheral	JJ
cord-017772-zpf1xjqi	30	9	blood	blood	NN
cord-017772-zpf1xjqi	30	10	smear	smear	NN
cord-017772-zpf1xjqi	30	11	and	and	CC
cord-017772-zpf1xjqi	30	12	re	re	JJ
cord-017772-zpf1xjqi	30	13	-	-	JJ
cord-017772-zpf1xjqi	30	14	drawing	draw	VBG
cord-017772-zpf1xjqi	30	15	blood	blood	NN
cord-017772-zpf1xjqi	30	16	using	use	VBG
cord-017772-zpf1xjqi	30	17	heparin	heparin	NN
cord-017772-zpf1xjqi	30	18	or	or	CC
cord-017772-zpf1xjqi	30	19	citrate	citrate	NN
cord-017772-zpf1xjqi	30	20	containing	contain	VBG
cord-017772-zpf1xjqi	30	21	collection	collection	NN
cord-017772-zpf1xjqi	30	22	tubes	tube	NNS
cord-017772-zpf1xjqi	30	23	can	can	MD
cord-017772-zpf1xjqi	30	24	help	help	VB
cord-017772-zpf1xjqi	30	25	confirm	confirm	VB
cord-017772-zpf1xjqi	30	26	the	the	DT
cord-017772-zpf1xjqi	30	27	diagnosis	diagnosis	NN
cord-017772-zpf1xjqi	30	28	.	.	.
cord-017772-zpf1xjqi	31	1	Step	step	NN
cord-017772-zpf1xjqi	31	2	2	2	CD
cord-017772-zpf1xjqi	31	3	:	:	:
cord-017772-zpf1xjqi	31	4	Is	be	VBZ
cord-017772-zpf1xjqi	31	5	the	the	DT
cord-017772-zpf1xjqi	31	6	Patient	Patient	NNP
cord-017772-zpf1xjqi	31	7	Bleeding	bleed	VBG
cord-017772-zpf1xjqi	31	8	?	?	.
cord-017772-zpf1xjqi	32	1	There	there	EX
cord-017772-zpf1xjqi	32	2	is	be	VBZ
cord-017772-zpf1xjqi	32	3	a	a	DT
cord-017772-zpf1xjqi	32	4	consensus	consensus	NN
cord-017772-zpf1xjqi	32	5	that	that	WDT
cord-017772-zpf1xjqi	32	6	patients	patient	NNS
cord-017772-zpf1xjqi	32	7	with	with	IN
cord-017772-zpf1xjqi	32	8	clinically	clinically	RB
cord-017772-zpf1xjqi	32	9	significant	significant	JJ
cord-017772-zpf1xjqi	32	10	bleeding	bleeding	NN
cord-017772-zpf1xjqi	32	11	should	should	MD
cord-017772-zpf1xjqi	32	12	be	be	VB
cord-017772-zpf1xjqi	32	13	transfused	transfuse	VBN
cord-017772-zpf1xjqi	32	14	to	to	IN
cord-017772-zpf1xjqi	32	15	a	a	DT
cord-017772-zpf1xjqi	32	16	platelet	platelet	NN
cord-017772-zpf1xjqi	32	17	count	count	NN
cord-017772-zpf1xjqi	32	18	of	of	IN
cord-017772-zpf1xjqi	32	19	>	>	$
cord-017772-zpf1xjqi	32	20	50	50	CD
cord-017772-zpf1xjqi	32	21	×	×	NN
cord-017772-zpf1xjqi	32	22	10	10	CD
cord-017772-zpf1xjqi	32	23	9	9	CD
cord-017772-zpf1xjqi	32	24	•	•	NNS
cord-017772-zpf1xjqi	33	1	If	if	IN
cord-017772-zpf1xjqi	33	2	platelet	platelet	NN
cord-017772-zpf1xjqi	33	3	clumps	clump	NNS
cord-017772-zpf1xjqi	33	4	seen	see	VBN
cord-017772-zpf1xjqi	33	5	on	on	IN
cord-017772-zpf1xjqi	33	6	smear	smear	NN
cord-017772-zpf1xjqi	33	7	,	,	,
cord-017772-zpf1xjqi	33	8	repeat	repeat	VB
cord-017772-zpf1xjqi	33	9	blood	blood	NN
cord-017772-zpf1xjqi	33	10	draw	draw	VBP
cord-017772-zpf1xjqi	33	11	in	in	IN
cord-017772-zpf1xjqi	33	12	non	non	JJ
cord-017772-zpf1xjqi	33	13	-	-	JJ
cord-017772-zpf1xjqi	33	14	EDTA	edta	JJ
cord-017772-zpf1xjqi	33	15	collection	collection	NN
cord-017772-zpf1xjqi	33	16	tube	tube	NN
cord-017772-zpf1xjqi	34	1	•	•	NNP
cord-017772-zpf1xjqi	35	1	Platelet	platelet	NN
cord-017772-zpf1xjqi	35	2	goal	goal	NN
cord-017772-zpf1xjqi	36	1	>	>	XX
cord-017772-zpf1xjqi	37	1	50	50	CD
cord-017772-zpf1xjqi	37	2	x	x	SYM
cord-017772-zpf1xjqi	37	3	10	10	CD
cord-017772-zpf1xjqi	37	4	9	9	CD
cord-017772-zpf1xjqi	37	5	cells	cell	NNS
cord-017772-zpf1xjqi	37	6	/	/	SYM
cord-017772-zpf1xjqi	37	7	L	l	NN
cord-017772-zpf1xjqi	37	8	in	in	IN
cord-017772-zpf1xjqi	37	9	non	non	JJ
cord-017772-zpf1xjqi	37	10	-	-	JJ
cord-017772-zpf1xjqi	37	11	CNS	cns	JJ
cord-017772-zpf1xjqi	37	12	bleeding	bleed	VBG
cord-017772-zpf1xjqi	37	13	[	[	-LRB-
cord-017772-zpf1xjqi	37	14	4	4	CD
cord-017772-zpf1xjqi	37	15	,	,	,
cord-017772-zpf1xjqi	37	16	19	19	CD
cord-017772-zpf1xjqi	37	17	,	,	,
cord-017772-zpf1xjqi	37	18	20	20	CD
cord-017772-zpf1xjqi	37	19	]	]	-RRB-
cord-017772-zpf1xjqi	38	1	The	the	DT
cord-017772-zpf1xjqi	38	2	transfusion	transfusion	NN
cord-017772-zpf1xjqi	38	3	threshold	threshold	NN
cord-017772-zpf1xjqi	38	4	should	should	MD
cord-017772-zpf1xjqi	38	5	be	be	VB
cord-017772-zpf1xjqi	38	6	increased	increase	VBN
cord-017772-zpf1xjqi	38	7	to	to	IN
cord-017772-zpf1xjqi	38	8	100	100	CD
cord-017772-zpf1xjqi	38	9	×	×	NN
cord-017772-zpf1xjqi	38	10	10	10	CD
cord-017772-zpf1xjqi	38	11	9	9	CD
cord-017772-zpf1xjqi	38	12	cells	cell	NNS
cord-017772-zpf1xjqi	38	13	/	/	SYM
cord-017772-zpf1xjqi	38	14	L	l	NN
cord-017772-zpf1xjqi	38	15	in	in	IN
cord-017772-zpf1xjqi	38	16	patients	patient	NNS
cord-017772-zpf1xjqi	38	17	with	with	IN
cord-017772-zpf1xjqi	38	18	intracranial	intracranial	JJ
cord-017772-zpf1xjqi	38	19	bleeding	bleed	VBG
cord-017772-zpf1xjqi	38	20	[	[	-LRB-
cord-017772-zpf1xjqi	38	21	21	21	CD
cord-017772-zpf1xjqi	38	22	]	]	-RRB-
cord-017772-zpf1xjqi	38	23	.	.	.
cord-017772-zpf1xjqi	39	1	Thrombotic	thrombotic	JJ
cord-017772-zpf1xjqi	39	2	microangiopathy	microangiopathy	NN
cord-017772-zpf1xjqi	39	3	(	(	-LRB-
cord-017772-zpf1xjqi	39	4	TMA	TMA	NNP
cord-017772-zpf1xjqi	39	5	)	)	-RRB-
cord-017772-zpf1xjqi	39	6	is	be	VBZ
cord-017772-zpf1xjqi	39	7	a	a	DT
cord-017772-zpf1xjqi	39	8	pathologic	pathologic	JJ
cord-017772-zpf1xjqi	39	9	term	term	NN
cord-017772-zpf1xjqi	39	10	used	use	VBN
cord-017772-zpf1xjqi	39	11	to	to	TO
cord-017772-zpf1xjqi	39	12	describe	describe	VB
cord-017772-zpf1xjqi	39	13	microvascular	microvascular	JJ
cord-017772-zpf1xjqi	39	14	thrombosis	thrombosis	NN
cord-017772-zpf1xjqi	39	15	in	in	IN
cord-017772-zpf1xjqi	39	16	the	the	DT
cord-017772-zpf1xjqi	39	17	arterioles	arteriole	NNS
cord-017772-zpf1xjqi	39	18	and	and	CC
cord-017772-zpf1xjqi	39	19	capillaries	capillary	NNS
cord-017772-zpf1xjqi	39	20	[	[	-LRB-
cord-017772-zpf1xjqi	39	21	22	22	CD
cord-017772-zpf1xjqi	39	22	]	]	-RRB-
cord-017772-zpf1xjqi	39	23	.	.	.
cord-017772-zpf1xjqi	40	1	The	the	DT
cord-017772-zpf1xjqi	40	2	key	key	JJ
cord-017772-zpf1xjqi	40	3	clinical	clinical	JJ
cord-017772-zpf1xjqi	40	4	manifestations	manifestation	NNS
cord-017772-zpf1xjqi	40	5	of	of	IN
cord-017772-zpf1xjqi	40	6	TMAs	TMAs	NNP
cord-017772-zpf1xjqi	40	7	are	be	VBP
cord-017772-zpf1xjqi	40	8	microangiopathic	microangiopathic	JJ
cord-017772-zpf1xjqi	40	9	hemolytic	hemolytic	JJ
cord-017772-zpf1xjqi	40	10	anemia	anemia	NN
cord-017772-zpf1xjqi	40	11	(	(	-LRB-
cord-017772-zpf1xjqi	40	12	MAHA	MAHA	NNP
cord-017772-zpf1xjqi	40	13	)	)	-RRB-
cord-017772-zpf1xjqi	40	14	and	and	CC
cord-017772-zpf1xjqi	40	15	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	40	16	.	.	.
cord-017772-zpf1xjqi	41	1	TMAs	TMAs	NNP
cord-017772-zpf1xjqi	41	2	are	be	VBP
cord-017772-zpf1xjqi	41	3	a	a	DT
cord-017772-zpf1xjqi	41	4	diverse	diverse	JJ
cord-017772-zpf1xjqi	41	5	group	group	NN
cord-017772-zpf1xjqi	41	6	of	of	IN
cord-017772-zpf1xjqi	41	7	disorders	disorder	NNS
cord-017772-zpf1xjqi	41	8	that	that	WDT
cord-017772-zpf1xjqi	41	9	can	can	MD
cord-017772-zpf1xjqi	41	10	be	be	VB
cord-017772-zpf1xjqi	41	11	classified	classify	VBN
cord-017772-zpf1xjqi	41	12	broadly	broadly	RB
cord-017772-zpf1xjqi	41	13	as	as	IN
cord-017772-zpf1xjqi	41	14	primary	primary	JJ
cord-017772-zpf1xjqi	41	15	(	(	-LRB-
cord-017772-zpf1xjqi	41	16	thrombotic	thrombotic	JJ
cord-017772-zpf1xjqi	41	17	thrombocytopenic	thrombocytopenic	JJ
cord-017772-zpf1xjqi	41	18	purpura	purpura	NN
cord-017772-zpf1xjqi	41	19	,	,	,
cord-017772-zpf1xjqi	41	20	hemolytic	hemolytic	JJ
cord-017772-zpf1xjqi	41	21	uremic	uremic	JJ
cord-017772-zpf1xjqi	41	22	syndrome	syndrome	NN
cord-017772-zpf1xjqi	41	23	,	,	,
cord-017772-zpf1xjqi	41	24	drug	drug	NN
cord-017772-zpf1xjqi	41	25	-	-	HYPH
cord-017772-zpf1xjqi	41	26	mediated	mediate	VBN
cord-017772-zpf1xjqi	41	27	,	,	,
cord-017772-zpf1xjqi	41	28	etc	etc	FW
cord-017772-zpf1xjqi	41	29	.	.	.
cord-017772-zpf1xjqi	41	30	)	)	-RRB-
cord-017772-zpf1xjqi	41	31	or	or	CC
cord-017772-zpf1xjqi	41	32	secondary	secondary	JJ
cord-017772-zpf1xjqi	41	33	to	to	IN
cord-017772-zpf1xjqi	41	34	a	a	DT
cord-017772-zpf1xjqi	41	35	systemic	systemic	JJ
cord-017772-zpf1xjqi	41	36	disorder	disorder	NN
cord-017772-zpf1xjqi	41	37	(	(	-LRB-
cord-017772-zpf1xjqi	41	38	disseminated	disseminate	VBN
cord-017772-zpf1xjqi	41	39	intravascular	intravascular	JJ
cord-017772-zpf1xjqi	41	40	coagulation	coagulation	NN
cord-017772-zpf1xjqi	41	41	,	,	,
cord-017772-zpf1xjqi	41	42	severe	severe	JJ
cord-017772-zpf1xjqi	41	43	hypertension	hypertension	NN
cord-017772-zpf1xjqi	41	44	,	,	,
cord-017772-zpf1xjqi	41	45	hemolysis	hemolysis	NN
cord-017772-zpf1xjqi	41	46	with	with	IN
cord-017772-zpf1xjqi	41	47	elevated	elevated	JJ
cord-017772-zpf1xjqi	41	48	liver	liver	NN
cord-017772-zpf1xjqi	41	49	enzymes	enzyme	NNS
cord-017772-zpf1xjqi	41	50	and	and	CC
cord-017772-zpf1xjqi	41	51	low	low	JJ
cord-017772-zpf1xjqi	41	52	platelets	platelet	NNS
cord-017772-zpf1xjqi	41	53	during	during	IN
cord-017772-zpf1xjqi	41	54	pregnancy	pregnancy	NN
cord-017772-zpf1xjqi	41	55	,	,	,
cord-017772-zpf1xjqi	41	56	etc	etc	FW
cord-017772-zpf1xjqi	41	57	.	.	.
cord-017772-zpf1xjqi	41	58	)	)	-RRB-
cord-017772-zpf1xjqi	42	1	[	[	-LRB-
cord-017772-zpf1xjqi	42	2	23	23	CD
cord-017772-zpf1xjqi	42	3	]	]	-RRB-
cord-017772-zpf1xjqi	42	4	.	.	.
cord-017772-zpf1xjqi	43	1	While	while	IN
cord-017772-zpf1xjqi	43	2	diseases	disease	NNS
cord-017772-zpf1xjqi	43	3	like	like	IN
cord-017772-zpf1xjqi	43	4	thrombotic	thrombotic	JJ
cord-017772-zpf1xjqi	43	5	thrombocytopenic	thrombocytopenic	JJ
cord-017772-zpf1xjqi	43	6	purpura	purpura	NN
cord-017772-zpf1xjqi	43	7	(	(	-LRB-
cord-017772-zpf1xjqi	43	8	TTP	TTP	NNP
cord-017772-zpf1xjqi	43	9	)	)	-RRB-
cord-017772-zpf1xjqi	43	10	are	be	VBP
cord-017772-zpf1xjqi	43	11	uncommon	uncommon	JJ
cord-017772-zpf1xjqi	43	12	,	,	,
cord-017772-zpf1xjqi	43	13	their	-PRON-	PRP$
cord-017772-zpf1xjqi	43	14	prompt	prompt	JJ
cord-017772-zpf1xjqi	43	15	recognition	recognition	NN
cord-017772-zpf1xjqi	43	16	is	be	VBZ
cord-017772-zpf1xjqi	43	17	critical	critical	JJ
cord-017772-zpf1xjqi	43	18	as	as	IN
cord-017772-zpf1xjqi	43	19	delayed	delay	VBN
cord-017772-zpf1xjqi	43	20	or	or	CC
cord-017772-zpf1xjqi	43	21	missed	miss	VBN
cord-017772-zpf1xjqi	43	22	diagnosis	diagnosis	NN
cord-017772-zpf1xjqi	43	23	can	can	MD
cord-017772-zpf1xjqi	43	24	lead	lead	VB
cord-017772-zpf1xjqi	43	25	to	to	IN
cord-017772-zpf1xjqi	43	26	significant	significant	JJ
cord-017772-zpf1xjqi	43	27	patient	patient	JJ
cord-017772-zpf1xjqi	43	28	harm	harm	NN
cord-017772-zpf1xjqi	43	29	.	.	.
cord-017772-zpf1xjqi	44	1	TTP	TTP	NNP
cord-017772-zpf1xjqi	44	2	and	and	CC
cord-017772-zpf1xjqi	44	3	disseminated	disseminate	VBN
cord-017772-zpf1xjqi	44	4	intravascular	intravascular	JJ
cord-017772-zpf1xjqi	44	5	coagulation	coagulation	NN
cord-017772-zpf1xjqi	44	6	(	(	-LRB-
cord-017772-zpf1xjqi	44	7	DIC	DIC	NNP
cord-017772-zpf1xjqi	44	8	)	)	-RRB-
cord-017772-zpf1xjqi	44	9	will	will	MD
cord-017772-zpf1xjqi	44	10	be	be	VB
cord-017772-zpf1xjqi	44	11	reviewed	review	VBN
cord-017772-zpf1xjqi	44	12	here	here	RB
cord-017772-zpf1xjqi	44	13	as	as	IN
cord-017772-zpf1xjqi	44	14	examples	example	NNS
cord-017772-zpf1xjqi	44	15	of	of	IN
cord-017772-zpf1xjqi	44	16	primary	primary	JJ
cord-017772-zpf1xjqi	44	17	and	and	CC
cord-017772-zpf1xjqi	44	18	secondary	secondary	JJ
cord-017772-zpf1xjqi	44	19	TMAs	tmas	NN
cord-017772-zpf1xjqi	44	20	respectively	respectively	RB
cord-017772-zpf1xjqi	44	21	.	.	.
cord-017772-zpf1xjqi	45	1	TTP	TTP	NNP
cord-017772-zpf1xjqi	45	2	is	be	VBZ
cord-017772-zpf1xjqi	45	3	characterized	characterize	VBN
cord-017772-zpf1xjqi	45	4	by	by	IN
cord-017772-zpf1xjqi	45	5	a	a	DT
cord-017772-zpf1xjqi	45	6	functional	functional	JJ
cord-017772-zpf1xjqi	45	7	deficiency	deficiency	NN
cord-017772-zpf1xjqi	45	8	in	in	IN
cord-017772-zpf1xjqi	45	9	a	a	DT
cord-017772-zpf1xjqi	45	10	VWF	VWF	NNP
cord-017772-zpf1xjqi	45	11	cleaving	cleave	VBG
cord-017772-zpf1xjqi	45	12	protein	protein	NN
cord-017772-zpf1xjqi	45	13	termed	term	VBN
cord-017772-zpf1xjqi	45	14	,	,	,
cord-017772-zpf1xjqi	45	15	"	"	''
cord-017772-zpf1xjqi	45	16	an	an	DT
cord-017772-zpf1xjqi	45	17	acronym	acronym	NN
cord-017772-zpf1xjqi	45	18	for	for	IN
cord-017772-zpf1xjqi	45	19	a	a	DT
cord-017772-zpf1xjqi	45	20	disintegrin	disintegrin	NNP
cord-017772-zpf1xjqi	45	21	and	and	CC
cord-017772-zpf1xjqi	45	22	metalloprotease	metalloprotease	NN
cord-017772-zpf1xjqi	45	23	with	with	IN
cord-017772-zpf1xjqi	45	24	thrombospondin-1-like	thrombospondin-1-like	NN
cord-017772-zpf1xjqi	45	25	-	-	HYPH
cord-017772-zpf1xjqi	45	26	domains	domain	NNS
cord-017772-zpf1xjqi	45	27	"	"	''
cord-017772-zpf1xjqi	45	28	(	(	-LRB-
cord-017772-zpf1xjqi	45	29	ADAMTS	ADAMTS	NNP
cord-017772-zpf1xjqi	45	30	13	13	CD
cord-017772-zpf1xjqi	45	31	)	)	-RRB-
cord-017772-zpf1xjqi	45	32	[	[	-LRB-
cord-017772-zpf1xjqi	45	33	24	24	CD
cord-017772-zpf1xjqi	45	34	]	]	-RRB-
cord-017772-zpf1xjqi	45	35	.	.	.
cord-017772-zpf1xjqi	46	1	With	with	IN
cord-017772-zpf1xjqi	46	2	a	a	DT
cord-017772-zpf1xjqi	46	3	functional	functional	JJ
cord-017772-zpf1xjqi	46	4	deficiency	deficiency	NN
cord-017772-zpf1xjqi	46	5	of	of	IN
cord-017772-zpf1xjqi	46	6	ADAMTS	ADAMTS	NNP
cord-017772-zpf1xjqi	46	7	13	13	CD
cord-017772-zpf1xjqi	46	8	,	,	,
cord-017772-zpf1xjqi	46	9	large	large	JJ
cord-017772-zpf1xjqi	46	10	VWF	VWF	NNP
cord-017772-zpf1xjqi	46	11	multimers	multimer	NNS
cord-017772-zpf1xjqi	46	12	accumulate	accumulate	VBP
cord-017772-zpf1xjqi	46	13	,	,	,
cord-017772-zpf1xjqi	46	14	triggering	trigger	VBG
cord-017772-zpf1xjqi	46	15	platelet	platelet	NN
cord-017772-zpf1xjqi	46	16	adhesion	adhesion	NN
cord-017772-zpf1xjqi	46	17	,	,	,
cord-017772-zpf1xjqi	46	18	activation	activation	NN
cord-017772-zpf1xjqi	46	19	,	,	,
cord-017772-zpf1xjqi	46	20	and	and	CC
cord-017772-zpf1xjqi	46	21	the	the	DT
cord-017772-zpf1xjqi	46	22	formation	formation	NN
cord-017772-zpf1xjqi	46	23	of	of	IN
cord-017772-zpf1xjqi	46	24	platelet	platelet	NN
cord-017772-zpf1xjqi	46	25	rich	rich	JJ
cord-017772-zpf1xjqi	46	26	microthrombi	microthrombi	NN
cord-017772-zpf1xjqi	46	27	[	[	-LRB-
cord-017772-zpf1xjqi	46	28	25	25	CD
cord-017772-zpf1xjqi	46	29	]	]	-RRB-
cord-017772-zpf1xjqi	46	30	.	.	.
cord-017772-zpf1xjqi	47	1	TTP	TTP	NNP
cord-017772-zpf1xjqi	47	2	is	be	VBZ
cord-017772-zpf1xjqi	47	3	a	a	DT
cord-017772-zpf1xjqi	47	4	rare	rare	JJ
cord-017772-zpf1xjqi	47	5	disease	disease	NN
cord-017772-zpf1xjqi	47	6	with	with	IN
cord-017772-zpf1xjqi	47	7	an	an	DT
cord-017772-zpf1xjqi	47	8	incidence	incidence	NN
cord-017772-zpf1xjqi	47	9	of	of	IN
cord-017772-zpf1xjqi	47	10	10	10	CD
cord-017772-zpf1xjqi	47	11	cases	case	NNS
cord-017772-zpf1xjqi	47	12	per	per	IN
cord-017772-zpf1xjqi	47	13	million	million	CD
cord-017772-zpf1xjqi	47	14	in	in	IN
cord-017772-zpf1xjqi	47	15	the	the	DT
cord-017772-zpf1xjqi	47	16	United	United	NNP
cord-017772-zpf1xjqi	47	17	States	States	NNP
cord-017772-zpf1xjqi	47	18	[	[	-LRB-
cord-017772-zpf1xjqi	47	19	26	26	CD
cord-017772-zpf1xjqi	47	20	]	]	-RRB-
cord-017772-zpf1xjqi	47	21	.	.	.
cord-017772-zpf1xjqi	48	1	Roughly	roughly	RB
cord-017772-zpf1xjqi	48	2	75	75	CD
cord-017772-zpf1xjqi	48	3	%	%	NN
cord-017772-zpf1xjqi	48	4	of	of	IN
cord-017772-zpf1xjqi	48	5	cases	case	NNS
cord-017772-zpf1xjqi	48	6	of	of	IN
cord-017772-zpf1xjqi	48	7	TTP	TTP	NNP
cord-017772-zpf1xjqi	48	8	are	be	VBP
cord-017772-zpf1xjqi	48	9	acquired	acquire	VBN
cord-017772-zpf1xjqi	48	10	,	,	,
cord-017772-zpf1xjqi	48	11	caused	cause	VBN
cord-017772-zpf1xjqi	48	12	by	by	IN
cord-017772-zpf1xjqi	48	13	the	the	DT
cord-017772-zpf1xjqi	48	14	production	production	NN
cord-017772-zpf1xjqi	48	15	of	of	IN
cord-017772-zpf1xjqi	48	16	IgG	IgG	NNP
cord-017772-zpf1xjqi	48	17	autoantibodies	autoantibody	NNS
cord-017772-zpf1xjqi	48	18	against	against	IN
cord-017772-zpf1xjqi	48	19	ADAMTS	ADAMTS	NNP
cord-017772-zpf1xjqi	48	20	13	13	CD
cord-017772-zpf1xjqi	48	21	[	[	-LRB-
cord-017772-zpf1xjqi	48	22	25	25	CD
cord-017772-zpf1xjqi	48	23	]	]	-RRB-
cord-017772-zpf1xjqi	48	24	.	.	.
cord-017772-zpf1xjqi	49	1	Antibody	antibody	NN
cord-017772-zpf1xjqi	49	2	production	production	NN
cord-017772-zpf1xjqi	49	3	can	can	MD
cord-017772-zpf1xjqi	49	4	be	be	VB
cord-017772-zpf1xjqi	49	5	idiopathic	idiopathic	JJ
cord-017772-zpf1xjqi	49	6	(	(	-LRB-
cord-017772-zpf1xjqi	49	7	≅50	≅50	CD
cord-017772-zpf1xjqi	49	8	%	%	NN
cord-017772-zpf1xjqi	49	9	of	of	IN
cord-017772-zpf1xjqi	49	10	cases	case	NNS
cord-017772-zpf1xjqi	49	11	)	)	-RRB-
cord-017772-zpf1xjqi	49	12	or	or	CC
cord-017772-zpf1xjqi	49	13	driven	drive	VBN
cord-017772-zpf1xjqi	49	14	by	by	IN
cord-017772-zpf1xjqi	49	15	a	a	DT
cord-017772-zpf1xjqi	49	16	variety	variety	NN
cord-017772-zpf1xjqi	49	17	of	of	IN
cord-017772-zpf1xjqi	49	18	conditions	condition	NNS
cord-017772-zpf1xjqi	49	19	including	include	VBG
cord-017772-zpf1xjqi	49	20	malignancy	malignancy	NN
cord-017772-zpf1xjqi	49	21	,	,	,
cord-017772-zpf1xjqi	49	22	human	human	JJ
cord-017772-zpf1xjqi	49	23	immunodeficiency	immunodeficiency	NN
cord-017772-zpf1xjqi	49	24	virus	virus	NN
cord-017772-zpf1xjqi	49	25	infection	infection	NN
cord-017772-zpf1xjqi	49	26	,	,	,
cord-017772-zpf1xjqi	49	27	pregnancy	pregnancy	NN
cord-017772-zpf1xjqi	49	28	,	,	,
cord-017772-zpf1xjqi	49	29	autoimmune	autoimmune	JJ
cord-017772-zpf1xjqi	49	30	disease	disease	NN
cord-017772-zpf1xjqi	49	31	,	,	,
cord-017772-zpf1xjqi	49	32	medications	medication	NNS
cord-017772-zpf1xjqi	49	33	,	,	,
cord-017772-zpf1xjqi	49	34	and	and	CC
cord-017772-zpf1xjqi	49	35	following	follow	VBG
cord-017772-zpf1xjqi	49	36	organ	organ	NN
cord-017772-zpf1xjqi	49	37	transplantation	transplantation	NN
cord-017772-zpf1xjqi	49	38	[	[	-LRB-
cord-017772-zpf1xjqi	49	39	27	27	CD
cord-017772-zpf1xjqi	49	40	]	]	-RRB-
cord-017772-zpf1xjqi	49	41	.	.	.
cord-017772-zpf1xjqi	50	1	TTP	TTP	NNP
cord-017772-zpf1xjqi	50	2	has	have	VBZ
cord-017772-zpf1xjqi	50	3	historically	historically	RB
cord-017772-zpf1xjqi	50	4	been	be	VBN
cord-017772-zpf1xjqi	50	5	associated	associate	VBN
cord-017772-zpf1xjqi	50	6	with	with	IN
cord-017772-zpf1xjqi	50	7	a	a	DT
cord-017772-zpf1xjqi	50	8	clinical	clinical	JJ
cord-017772-zpf1xjqi	50	9	pentad	pentad	NN
cord-017772-zpf1xjqi	50	10	of	of	IN
cord-017772-zpf1xjqi	50	11	MAHA	MAHA	NNP
cord-017772-zpf1xjqi	50	12	,	,	,
cord-017772-zpf1xjqi	50	13	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	50	14	,	,	,
cord-017772-zpf1xjqi	50	15	neurologic	neurologic	JJ
cord-017772-zpf1xjqi	50	16	symptoms	symptom	NNS
cord-017772-zpf1xjqi	50	17	,	,	,
cord-017772-zpf1xjqi	50	18	renal	renal	JJ
cord-017772-zpf1xjqi	50	19	impairment	impairment	NN
cord-017772-zpf1xjqi	50	20	,	,	,
cord-017772-zpf1xjqi	50	21	and	and	CC
cord-017772-zpf1xjqi	50	22	fever	fever	NN
cord-017772-zpf1xjqi	50	23	.	.	.
cord-017772-zpf1xjqi	51	1	In	in	IN
cord-017772-zpf1xjqi	51	2	the	the	DT
cord-017772-zpf1xjqi	51	3	modern	modern	JJ
cord-017772-zpf1xjqi	51	4	era	era	NN
cord-017772-zpf1xjqi	51	5	,	,	,
cord-017772-zpf1xjqi	51	6	this	this	DT
cord-017772-zpf1xjqi	51	7	constellation	constellation	NN
cord-017772-zpf1xjqi	51	8	of	of	IN
cord-017772-zpf1xjqi	51	9	symptoms	symptom	NNS
cord-017772-zpf1xjqi	51	10	is	be	VBZ
cord-017772-zpf1xjqi	51	11	rarely	rarely	RB
cord-017772-zpf1xjqi	51	12	seen	see	VBN
cord-017772-zpf1xjqi	51	13	[	[	-LRB-
cord-017772-zpf1xjqi	51	14	27	27	CD
cord-017772-zpf1xjqi	51	15	]	]	-RRB-
cord-017772-zpf1xjqi	51	16	.	.	.
cord-017772-zpf1xjqi	52	1	While	while	IN
cord-017772-zpf1xjqi	52	2	MAHA	MAHA	NNP
cord-017772-zpf1xjqi	52	3	and	and	CC
cord-017772-zpf1xjqi	52	4	thrombocytopenia	thrombocytopenia	NNS
cord-017772-zpf1xjqi	52	5	are	be	VBP
cord-017772-zpf1xjqi	52	6	universally	universally	RB
cord-017772-zpf1xjqi	52	7	present	present	JJ
cord-017772-zpf1xjqi	52	8	,	,	,
cord-017772-zpf1xjqi	52	9	upwards	upwards	RB
cord-017772-zpf1xjqi	52	10	of	of	IN
cord-017772-zpf1xjqi	52	11	90	90	CD
cord-017772-zpf1xjqi	52	12	%	%	NN
cord-017772-zpf1xjqi	52	13	of	of	IN
cord-017772-zpf1xjqi	52	14	patients	patient	NNS
cord-017772-zpf1xjqi	52	15	will	will	MD
cord-017772-zpf1xjqi	52	16	be	be	VB
cord-017772-zpf1xjqi	52	17	afebrile	afebrile	JJ
cord-017772-zpf1xjqi	52	18	and	and	CC
cord-017772-zpf1xjqi	52	19	50	50	CD
cord-017772-zpf1xjqi	52	20	%	%	NN
cord-017772-zpf1xjqi	52	21	will	will	MD
cord-017772-zpf1xjqi	52	22	have	have	VB
cord-017772-zpf1xjqi	52	23	either	either	CC
cord-017772-zpf1xjqi	52	24	normal	normal	JJ
cord-017772-zpf1xjqi	52	25	mental	mental	JJ
cord-017772-zpf1xjqi	52	26	status	status	NN
cord-017772-zpf1xjqi	52	27	or	or	CC
cord-017772-zpf1xjqi	52	28	renal	renal	JJ
cord-017772-zpf1xjqi	52	29	function	function	NN
cord-017772-zpf1xjqi	52	30	[	[	-LRB-
cord-017772-zpf1xjqi	52	31	28	28	CD
cord-017772-zpf1xjqi	52	32	]	]	-RRB-
cord-017772-zpf1xjqi	52	33	.	.	.
cord-017772-zpf1xjqi	53	1	Presenting	present	VBG
cord-017772-zpf1xjqi	53	2	symptoms	symptom	NNS
cord-017772-zpf1xjqi	53	3	are	be	VBP
cord-017772-zpf1xjqi	53	4	often	often	RB
cord-017772-zpf1xjqi	53	5	non	non	JJ
cord-017772-zpf1xjqi	53	6	-	-	JJ
cord-017772-zpf1xjqi	53	7	specific	specific	JJ
cord-017772-zpf1xjqi	53	8	and	and	CC
cord-017772-zpf1xjqi	53	9	include	include	VBP
cord-017772-zpf1xjqi	53	10	nausea	nausea	NN
cord-017772-zpf1xjqi	53	11	and	and	CC
cord-017772-zpf1xjqi	53	12	abdominal	abdominal	JJ
cord-017772-zpf1xjqi	53	13	pain	pain	NN
cord-017772-zpf1xjqi	53	14	[	[	-LRB-
cord-017772-zpf1xjqi	53	15	24	24	CD
cord-017772-zpf1xjqi	53	16	]	]	-RRB-
cord-017772-zpf1xjqi	53	17	.	.	.
cord-017772-zpf1xjqi	54	1	Initial	initial	JJ
cord-017772-zpf1xjqi	54	2	laboratory	laboratory	NN
cord-017772-zpf1xjqi	54	3	testing	testing	NN
cord-017772-zpf1xjqi	54	4	in	in	IN
cord-017772-zpf1xjqi	54	5	patients	patient	NNS
cord-017772-zpf1xjqi	54	6	with	with	IN
cord-017772-zpf1xjqi	54	7	suspected	suspect	VBN
cord-017772-zpf1xjqi	54	8	TTP	TTP	NNP
cord-017772-zpf1xjqi	54	9	should	should	MD
cord-017772-zpf1xjqi	54	10	confirm	confirm	VB
cord-017772-zpf1xjqi	54	11	the	the	DT
cord-017772-zpf1xjqi	54	12	presence	presence	NN
cord-017772-zpf1xjqi	54	13	of	of	IN
cord-017772-zpf1xjqi	54	14	hemolysis	hemolysis	NN
cord-017772-zpf1xjqi	54	15	(	(	-LRB-
cord-017772-zpf1xjqi	54	16	e.g.	e.g.	RB
cord-017772-zpf1xjqi	54	17	,	,	,
cord-017772-zpf1xjqi	54	18	an	an	DT
cord-017772-zpf1xjqi	54	19	elevated	elevated	JJ
cord-017772-zpf1xjqi	54	20	lactate	lactate	NN
cord-017772-zpf1xjqi	54	21	dehydrogenase	dehydrogenase	NN
cord-017772-zpf1xjqi	54	22	level	level	NN
cord-017772-zpf1xjqi	54	23	,	,	,
cord-017772-zpf1xjqi	54	24	low	low	JJ
cord-017772-zpf1xjqi	54	25	haptoglobin	haptoglobin	NN
cord-017772-zpf1xjqi	54	26	,	,	,
cord-017772-zpf1xjqi	54	27	elevated	elevated	JJ
cord-017772-zpf1xjqi	54	28	indirect	indirect	JJ
cord-017772-zpf1xjqi	54	29	bilirubin	bilirubin	NN
cord-017772-zpf1xjqi	54	30	,	,	,
cord-017772-zpf1xjqi	54	31	and	and	CC
cord-017772-zpf1xjqi	54	32	elevated	elevated	JJ
cord-017772-zpf1xjqi	54	33	reticulocyte	reticulocyte	NN
cord-017772-zpf1xjqi	54	34	index	index	NN
cord-017772-zpf1xjqi	54	35	)	)	-RRB-
cord-017772-zpf1xjqi	54	36	.	.	.
cord-017772-zpf1xjqi	55	1	In	in	IN
cord-017772-zpf1xjqi	55	2	contrast	contrast	NN
cord-017772-zpf1xjqi	55	3	to	to	IN
cord-017772-zpf1xjqi	55	4	DIC	DIC	NNP
cord-017772-zpf1xjqi	55	5	,	,	,
cord-017772-zpf1xjqi	55	6	coagulation	coagulation	NN
cord-017772-zpf1xjqi	55	7	parameters	parameter	NNS
cord-017772-zpf1xjqi	55	8	are	be	VBP
cord-017772-zpf1xjqi	55	9	typically	typically	RB
cord-017772-zpf1xjqi	55	10	normal	normal	JJ
cord-017772-zpf1xjqi	55	11	.	.	.
cord-017772-zpf1xjqi	56	1	A	a	DT
cord-017772-zpf1xjqi	56	2	peripheral	peripheral	JJ
cord-017772-zpf1xjqi	56	3	blood	blood	NN
cord-017772-zpf1xjqi	56	4	smear	smear	NN
cord-017772-zpf1xjqi	56	5	should	should	MD
cord-017772-zpf1xjqi	56	6	be	be	VB
cord-017772-zpf1xjqi	56	7	reviewed	review	VBN
cord-017772-zpf1xjqi	56	8	to	to	TO
cord-017772-zpf1xjqi	56	9	identify	identify	VB
cord-017772-zpf1xjqi	56	10	fragmented	fragmented	JJ
cord-017772-zpf1xjqi	56	11	red	red	JJ
cord-017772-zpf1xjqi	56	12	blood	blood	NN
cord-017772-zpf1xjqi	56	13	cells	cell	NNS
cord-017772-zpf1xjqi	56	14	called	call	VBD
cord-017772-zpf1xjqi	56	15	schistocytes	schistocytes	NNP
cord-017772-zpf1xjqi	56	16	-one	-one	:
cord-017772-zpf1xjqi	56	17	of	of	IN
cord-017772-zpf1xjqi	56	18	the	the	DT
cord-017772-zpf1xjqi	56	19	histologic	histologic	JJ
cord-017772-zpf1xjqi	56	20	hallmarks	hallmark	NNS
cord-017772-zpf1xjqi	56	21	of	of	IN
cord-017772-zpf1xjqi	56	22	TMA	TMA	NNP
cord-017772-zpf1xjqi	56	23	(	(	-LRB-
cord-017772-zpf1xjqi	56	24	Fig	Fig	NNP
cord-017772-zpf1xjqi	56	25	.	.	.
cord-017772-zpf1xjqi	56	26	83.2	83.2	CD
cord-017772-zpf1xjqi	56	27	)	)	-RRB-
cord-017772-zpf1xjqi	56	28	.	.	.
cord-017772-zpf1xjqi	57	1	Renal	renal	JJ
cord-017772-zpf1xjqi	57	2	and	and	CC
cord-017772-zpf1xjqi	57	3	cardiac	cardiac	JJ
cord-017772-zpf1xjqi	57	4	biomarkers	biomarker	NNS
cord-017772-zpf1xjqi	57	5	should	should	MD
cord-017772-zpf1xjqi	57	6	be	be	VB
cord-017772-zpf1xjqi	57	7	obtained	obtain	VBN
cord-017772-zpf1xjqi	57	8	to	to	IN
cord-017772-zpf1xjqi	57	9	screen	screen	NN
cord-017772-zpf1xjqi	57	10	for	for	IN
cord-017772-zpf1xjqi	57	11	organ	organ	NN
cord-017772-zpf1xjqi	57	12	dysfunction	dysfunction	NN
cord-017772-zpf1xjqi	57	13	.	.	.
cord-017772-zpf1xjqi	58	1	The	the	DT
cord-017772-zpf1xjqi	58	2	role	role	NN
cord-017772-zpf1xjqi	58	3	of	of	IN
cord-017772-zpf1xjqi	58	4	ADAMTS	ADAMTS	NNP
cord-017772-zpf1xjqi	58	5	13	13	CD
cord-017772-zpf1xjqi	58	6	assays	assay	NNS
cord-017772-zpf1xjqi	58	7	is	be	VBZ
cord-017772-zpf1xjqi	58	8	debated	debate	VBN
cord-017772-zpf1xjqi	58	9	[	[	-LRB-
cord-017772-zpf1xjqi	58	10	24	24	CD
cord-017772-zpf1xjqi	58	11	,	,	,
cord-017772-zpf1xjqi	58	12	25	25	CD
cord-017772-zpf1xjqi	58	13	]	]	-RRB-
cord-017772-zpf1xjqi	58	14	.	.	.
cord-017772-zpf1xjqi	59	1	A	a	DT
cord-017772-zpf1xjqi	59	2	severely	severely	RB
cord-017772-zpf1xjqi	59	3	low	low	JJ
cord-017772-zpf1xjqi	59	4	level	level	NN
cord-017772-zpf1xjqi	59	5	(	(	-LRB-
cord-017772-zpf1xjqi	59	6	<	<	NNP
cord-017772-zpf1xjqi	59	7	5	5	CD
cord-017772-zpf1xjqi	59	8	%	%	NN
cord-017772-zpf1xjqi	59	9	)	)	-RRB-
cord-017772-zpf1xjqi	59	10	confirms	confirm	VBZ
cord-017772-zpf1xjqi	59	11	the	the	DT
cord-017772-zpf1xjqi	59	12	diagnosis	diagnosis	NN
cord-017772-zpf1xjqi	59	13	of	of	IN
cord-017772-zpf1xjqi	59	14	TTP	TTP	NNP
cord-017772-zpf1xjqi	59	15	.	.	.
cord-017772-zpf1xjqi	60	1	However	however	RB
cord-017772-zpf1xjqi	60	2	,	,	,
cord-017772-zpf1xjqi	60	3	it	-PRON-	PRP
cord-017772-zpf1xjqi	60	4	is	be	VBZ
cord-017772-zpf1xjqi	60	5	imperative	imperative	JJ
cord-017772-zpf1xjqi	60	6	that	that	IN
cord-017772-zpf1xjqi	60	7	the	the	DT
cord-017772-zpf1xjqi	60	8	decision	decision	NN
cord-017772-zpf1xjqi	60	9	to	to	TO
cord-017772-zpf1xjqi	60	10	initiate	initiate	VB
cord-017772-zpf1xjqi	60	11	therapy	therapy	NN
cord-017772-zpf1xjqi	60	12	is	be	VBZ
cord-017772-zpf1xjqi	60	13	made	make	VBN
cord-017772-zpf1xjqi	60	14	urgently	urgently	RB
cord-017772-zpf1xjqi	60	15	on	on	IN
cord-017772-zpf1xjqi	60	16	the	the	DT
cord-017772-zpf1xjqi	60	17	basis	basis	NN
cord-017772-zpf1xjqi	60	18	of	of	IN
cord-017772-zpf1xjqi	60	19	an	an	DT
cord-017772-zpf1xjqi	60	20	initial	initial	JJ
cord-017772-zpf1xjqi	60	21	clinical	clinical	JJ
cord-017772-zpf1xjqi	60	22	and	and	CC
cord-017772-zpf1xjqi	60	23	laboratory	laboratory	NN
cord-017772-zpf1xjqi	60	24	evaluation	evaluation	NN
cord-017772-zpf1xjqi	60	25	without	without	IN
cord-017772-zpf1xjqi	60	26	waiting	wait	VBG
cord-017772-zpf1xjqi	60	27	for	for	IN
cord-017772-zpf1xjqi	60	28	ADAMTS	ADAMTS	NNP
cord-017772-zpf1xjqi	60	29	13	13	CD
cord-017772-zpf1xjqi	60	30	activity	activity	NN
cord-017772-zpf1xjqi	60	31	levels	level	NNS
cord-017772-zpf1xjqi	60	32	to	to	TO
cord-017772-zpf1xjqi	60	33	result	result	VB
cord-017772-zpf1xjqi	60	34	[	[	-LRB-
cord-017772-zpf1xjqi	60	35	29	29	CD
cord-017772-zpf1xjqi	60	36	]	]	-RRB-
cord-017772-zpf1xjqi	60	37	.	.	.
cord-017772-zpf1xjqi	61	1	TTP	TTP	NNP
cord-017772-zpf1xjqi	61	2	was	be	VBD
cord-017772-zpf1xjqi	61	3	previously	previously	RB
cord-017772-zpf1xjqi	61	4	viewed	view	VBN
cord-017772-zpf1xjqi	61	5	as	as	IN
cord-017772-zpf1xjqi	61	6	an	an	DT
cord-017772-zpf1xjqi	61	7	almost	almost	RB
cord-017772-zpf1xjqi	61	8	universally	universally	RB
cord-017772-zpf1xjqi	61	9	fatal	fatal	JJ
cord-017772-zpf1xjqi	61	10	diagnosis	diagnosis	NN
cord-017772-zpf1xjqi	61	11	.	.	.
cord-017772-zpf1xjqi	62	1	However	however	RB
cord-017772-zpf1xjqi	62	2	,	,	,
cord-017772-zpf1xjqi	62	3	with	with	IN
cord-017772-zpf1xjqi	62	4	the	the	DT
cord-017772-zpf1xjqi	62	5	rapid	rapid	JJ
cord-017772-zpf1xjqi	62	6	initiation	initiation	NN
cord-017772-zpf1xjqi	62	7	of	of	IN
cord-017772-zpf1xjqi	62	8	plasma	plasma	NN
cord-017772-zpf1xjqi	62	9	exchange	exchange	NN
cord-017772-zpf1xjqi	62	10	,	,	,
cord-017772-zpf1xjqi	62	11	survival	survival	NN
cord-017772-zpf1xjqi	62	12	rates	rate	NNS
cord-017772-zpf1xjqi	62	13	now	now	RB
cord-017772-zpf1xjqi	62	14	approach	approach	VBP
cord-017772-zpf1xjqi	62	15	90	90	CD
cord-017772-zpf1xjqi	62	16	%	%	NN
cord-017772-zpf1xjqi	62	17	[	[	-LRB-
cord-017772-zpf1xjqi	62	18	24	24	CD
cord-017772-zpf1xjqi	62	19	,	,	,
cord-017772-zpf1xjqi	62	20	30	30	CD
cord-017772-zpf1xjqi	62	21	]	]	-RRB-
cord-017772-zpf1xjqi	62	22	.	.	.
cord-017772-zpf1xjqi	63	1	Plasma	plasma	NN
cord-017772-zpf1xjqi	63	2	exchange	exchange	NN
cord-017772-zpf1xjqi	63	3	should	should	MD
cord-017772-zpf1xjqi	63	4	be	be	VB
cord-017772-zpf1xjqi	63	5	continued	continue	VBN
cord-017772-zpf1xjqi	63	6	until	until	IN
cord-017772-zpf1xjqi	63	7	platelet	platelet	NN
cord-017772-zpf1xjqi	63	8	counts	count	NNS
cord-017772-zpf1xjqi	63	9	are	be	VBP
cord-017772-zpf1xjqi	63	10	>	>	NFP
cord-017772-zpf1xjqi	63	11	150	150	CD
cord-017772-zpf1xjqi	63	12	×	×	NN
cord-017772-zpf1xjqi	63	13	10	10	CD
cord-017772-zpf1xjqi	63	14	9	9	CD
cord-017772-zpf1xjqi	63	15	cells	cell	NNS
cord-017772-zpf1xjqi	63	16	/	/	SYM
cord-017772-zpf1xjqi	63	17	L	l	NN
cord-017772-zpf1xjqi	63	18	for	for	IN
cord-017772-zpf1xjqi	63	19	2	2	CD
cord-017772-zpf1xjqi	63	20	days	day	NNS
cord-017772-zpf1xjqi	63	21	[	[	-LRB-
cord-017772-zpf1xjqi	63	22	29	29	CD
cord-017772-zpf1xjqi	63	23	]	]	-RRB-
cord-017772-zpf1xjqi	63	24	.	.	.
cord-017772-zpf1xjqi	64	1	Steroids	steroid	NNS
cord-017772-zpf1xjqi	64	2	and	and	CC
cord-017772-zpf1xjqi	64	3	rituximab	rituximab	NN
cord-017772-zpf1xjqi	64	4	may	may	MD
cord-017772-zpf1xjqi	64	5	have	have	VB
cord-017772-zpf1xjqi	64	6	a	a	DT
cord-017772-zpf1xjqi	64	7	role	role	NN
cord-017772-zpf1xjqi	64	8	in	in	IN
cord-017772-zpf1xjqi	64	9	the	the	DT
cord-017772-zpf1xjqi	64	10	treatment	treatment	NN
cord-017772-zpf1xjqi	64	11	of	of	IN
cord-017772-zpf1xjqi	64	12	refractory	refractory	JJ
cord-017772-zpf1xjqi	64	13	and	and	CC
cord-017772-zpf1xjqi	64	14	recurrent	recurrent	JJ
cord-017772-zpf1xjqi	64	15	disease	disease	NN
cord-017772-zpf1xjqi	64	16	[	[	-LRB-
cord-017772-zpf1xjqi	64	17	25	25	CD
cord-017772-zpf1xjqi	64	18	]	]	-RRB-
cord-017772-zpf1xjqi	64	19	.	.	.
cord-017772-zpf1xjqi	65	1	DIC	DIC	NNP
cord-017772-zpf1xjqi	65	2	is	be	VBZ
cord-017772-zpf1xjqi	65	3	defined	define	VBN
cord-017772-zpf1xjqi	65	4	by	by	IN
cord-017772-zpf1xjqi	65	5	the	the	DT
cord-017772-zpf1xjqi	65	6	International	International	NNP
cord-017772-zpf1xjqi	65	7	Society	Society	NNP
cord-017772-zpf1xjqi	65	8	on	on	IN
cord-017772-zpf1xjqi	65	9	Thrombosis	Thrombosis	NNP
cord-017772-zpf1xjqi	65	10	and	and	CC
cord-017772-zpf1xjqi	65	11	Haemostasis	Haemostasis	NNP
cord-017772-zpf1xjqi	65	12	(	(	-LRB-
cord-017772-zpf1xjqi	65	13	ISTH	ISTH	NNP
cord-017772-zpf1xjqi	65	14	)	)	-RRB-
cord-017772-zpf1xjqi	65	15	as	as	IN
cord-017772-zpf1xjqi	65	16	"	"	``
cord-017772-zpf1xjqi	65	17	an	an	DT
cord-017772-zpf1xjqi	65	18	acquired	acquire	VBN
cord-017772-zpf1xjqi	65	19	syndrome	syndrome	NN
cord-017772-zpf1xjqi	65	20	characterized	characterize	VBN
cord-017772-zpf1xjqi	65	21	by	by	IN
cord-017772-zpf1xjqi	65	22	the	the	DT
cord-017772-zpf1xjqi	65	23	intravascular	intravascular	JJ
cord-017772-zpf1xjqi	65	24	activation	activation	NN
cord-017772-zpf1xjqi	65	25	of	of	IN
cord-017772-zpf1xjqi	65	26	coagulation	coagulation	NN
cord-017772-zpf1xjqi	65	27	with	with	IN
cord-017772-zpf1xjqi	65	28	a	a	DT
cord-017772-zpf1xjqi	65	29	loss	loss	NN
cord-017772-zpf1xjqi	65	30	of	of	IN
cord-017772-zpf1xjqi	65	31	localization	localization	NN
cord-017772-zpf1xjqi	65	32	arising	arise	VBG
cord-017772-zpf1xjqi	65	33	from	from	IN
cord-017772-zpf1xjqi	65	34	different	different	JJ
cord-017772-zpf1xjqi	65	35	causes	cause	NNS
cord-017772-zpf1xjqi	65	36	.	.	.
cord-017772-zpf1xjqi	66	1	It	-PRON-	PRP
cord-017772-zpf1xjqi	66	2	can	can	MD
cord-017772-zpf1xjqi	66	3	originate	originate	VB
cord-017772-zpf1xjqi	66	4	from	from	IN
cord-017772-zpf1xjqi	66	5	and	and	CC
cord-017772-zpf1xjqi	66	6	cause	cause	VB
cord-017772-zpf1xjqi	66	7	damage	damage	NN
cord-017772-zpf1xjqi	66	8	to	to	IN
cord-017772-zpf1xjqi	66	9	the	the	DT
cord-017772-zpf1xjqi	66	10	microvasculature	microvasculature	NN
cord-017772-zpf1xjqi	66	11	,	,	,
cord-017772-zpf1xjqi	66	12	which	which	WDT
cord-017772-zpf1xjqi	66	13	if	if	IN
cord-017772-zpf1xjqi	66	14	sufficiently	sufficiently	RB
cord-017772-zpf1xjqi	66	15	severe	severe	JJ
cord-017772-zpf1xjqi	66	16	,	,	,
cord-017772-zpf1xjqi	66	17	can	can	MD
cord-017772-zpf1xjqi	66	18	produce	produce	VB
cord-017772-zpf1xjqi	66	19	organ	organ	NN
cord-017772-zpf1xjqi	66	20	dysfunction	dysfunction	NN
cord-017772-zpf1xjqi	66	21	.	.	.
cord-017772-zpf1xjqi	66	22	"	"	''
cord-017772-zpf1xjqi	67	1	[	[	-LRB-
cord-017772-zpf1xjqi	67	2	31	31	CD
cord-017772-zpf1xjqi	67	3	]	]	-RRB-
cord-017772-zpf1xjqi	68	1	The	the	DT
cord-017772-zpf1xjqi	68	2	pathobiology	pathobiology	NN
cord-017772-zpf1xjqi	68	3	of	of	IN
cord-017772-zpf1xjqi	68	4	DIC	DIC	NNP
cord-017772-zpf1xjqi	68	5	is	be	VBZ
cord-017772-zpf1xjqi	68	6	complex	complex	JJ
cord-017772-zpf1xjqi	68	7	and	and	CC
cord-017772-zpf1xjqi	68	8	is	be	VBZ
cord-017772-zpf1xjqi	68	9	driven	drive	VBN
cord-017772-zpf1xjqi	68	10	by	by	IN
cord-017772-zpf1xjqi	68	11	dysregulated	dysregulated	JJ
cord-017772-zpf1xjqi	68	12	coagulation	coagulation	NN
cord-017772-zpf1xjqi	68	13	and	and	CC
cord-017772-zpf1xjqi	68	14	fibrinolysis	fibrinolysis	NN
cord-017772-zpf1xjqi	68	15	pathways	pathway	NNS
cord-017772-zpf1xjqi	68	16	.	.	.
cord-017772-zpf1xjqi	69	1	A	a	DT
cord-017772-zpf1xjqi	69	2	central	central	JJ
cord-017772-zpf1xjqi	69	3	component	component	NN
cord-017772-zpf1xjqi	69	4	of	of	IN
cord-017772-zpf1xjqi	69	5	DIC	DIC	NNP
cord-017772-zpf1xjqi	69	6	is	be	VBZ
cord-017772-zpf1xjqi	69	7	excessive	excessive	JJ
cord-017772-zpf1xjqi	69	8	tissue	tissue	NN
cord-017772-zpf1xjqi	69	9	factor	factor	NN
cord-017772-zpf1xjqi	69	10	(	(	-LRB-
cord-017772-zpf1xjqi	69	11	TF	TF	NNP
cord-017772-zpf1xjqi	69	12	)	)	-RRB-
cord-017772-zpf1xjqi	69	13	expression	expression	NN
cord-017772-zpf1xjqi	69	14	and	and	CC
cord-017772-zpf1xjqi	69	15	thrombin	thrombin	JJ
cord-017772-zpf1xjqi	69	16	generation	generation	NN
cord-017772-zpf1xjqi	69	17	.	.	.
cord-017772-zpf1xjqi	70	1	Depending	depend	VBG
cord-017772-zpf1xjqi	70	2	on	on	IN
cord-017772-zpf1xjqi	70	3	the	the	DT
cord-017772-zpf1xjqi	70	4	clinical	clinical	JJ
cord-017772-zpf1xjqi	70	5	scenario	scenario	NN
cord-017772-zpf1xjqi	70	6	,	,	,
cord-017772-zpf1xjqi	70	7	this	this	DT
cord-017772-zpf1xjqi	70	8	can	can	MD
cord-017772-zpf1xjqi	70	9	be	be	VB
cord-017772-zpf1xjqi	70	10	caused	cause	VBN
cord-017772-zpf1xjqi	70	11	by	by	IN
cord-017772-zpf1xjqi	70	12	the	the	DT
cord-017772-zpf1xjqi	70	13	release	release	NN
cord-017772-zpf1xjqi	70	14	of	of	IN
cord-017772-zpf1xjqi	70	15	inflammatory	inflammatory	JJ
cord-017772-zpf1xjqi	70	16	cytokines	cytokine	NNS
cord-017772-zpf1xjqi	70	17	including	include	VBG
cord-017772-zpf1xjqi	70	18	IL-1	IL-1	NNP
cord-017772-zpf1xjqi	70	19	and	and	CC
cord-017772-zpf1xjqi	70	20	Il-6	Il-6	NNP
cord-017772-zpf1xjqi	70	21	,	,	,
cord-017772-zpf1xjqi	70	22	increased	increase	VBD
cord-017772-zpf1xjqi	70	23	TF	TF	NNP
cord-017772-zpf1xjqi	70	24	expression	expression	NN
cord-017772-zpf1xjqi	70	25	on	on	IN
cord-017772-zpf1xjqi	70	26	mononuclear	mononuclear	JJ
cord-017772-zpf1xjqi	70	27	cells	cell	NNS
cord-017772-zpf1xjqi	70	28	,	,	,
cord-017772-zpf1xjqi	70	29	injury	injury	NN
cord-017772-zpf1xjqi	70	30	to	to	IN
cord-017772-zpf1xjqi	70	31	vascular	vascular	JJ
cord-017772-zpf1xjqi	70	32	endothelial	endothelial	JJ
cord-017772-zpf1xjqi	70	33	cells	cell	NNS
cord-017772-zpf1xjqi	70	34	,	,	,
cord-017772-zpf1xjqi	70	35	and	and	CC
cord-017772-zpf1xjqi	70	36	exposure	exposure	NN
cord-017772-zpf1xjqi	70	37	to	to	IN
cord-017772-zpf1xjqi	70	38	pro	pro	JJ
cord-017772-zpf1xjqi	70	39	-	-	JJ
cord-017772-zpf1xjqi	70	40	coagulant	coagulant	JJ
cord-017772-zpf1xjqi	70	41	molecules	molecule	NNS
cord-017772-zpf1xjqi	70	42	(	(	-LRB-
cord-017772-zpf1xjqi	70	43	e.g.	e.g.	DT
cord-017772-zpf1xjqi	70	44	amniotic	amniotic	NN
cord-017772-zpf1xjqi	70	45	fluid	fluid	NN
cord-017772-zpf1xjqi	70	46	)	)	-RRB-
cord-017772-zpf1xjqi	70	47	[	[	-LRB-
cord-017772-zpf1xjqi	70	48	32	32	CD
cord-017772-zpf1xjqi	70	49	]	]	-RRB-
cord-017772-zpf1xjqi	70	50	.	.	.
cord-017772-zpf1xjqi	71	1	Activated	activate	VBN
cord-017772-zpf1xjqi	71	2	platelets	platelet	NNS
cord-017772-zpf1xjqi	71	3	contribute	contribute	VBP
cord-017772-zpf1xjqi	71	4	to	to	IN
cord-017772-zpf1xjqi	71	5	excessive	excessive	JJ
cord-017772-zpf1xjqi	71	6	thrombin	thrombin	JJ
cord-017772-zpf1xjqi	71	7	generation	generation	NN
cord-017772-zpf1xjqi	71	8	and	and	CC
cord-017772-zpf1xjqi	71	9	the	the	DT
cord-017772-zpf1xjqi	71	10	formation	formation	NN
cord-017772-zpf1xjqi	71	11	of	of	IN
cord-017772-zpf1xjqi	71	12	microvascular	microvascular	JJ
cord-017772-zpf1xjqi	71	13	clots	clot	NNS
cord-017772-zpf1xjqi	71	14	.	.	.
cord-017772-zpf1xjqi	72	1	Concurrently	concurrently	RB
cord-017772-zpf1xjqi	72	2	,	,	,
cord-017772-zpf1xjqi	72	3	Fragmented	fragmented	JJ
cord-017772-zpf1xjqi	72	4	red	red	JJ
cord-017772-zpf1xjqi	72	5	blood	blood	NN
cord-017772-zpf1xjqi	72	6	cells	cell	NNS
cord-017772-zpf1xjqi	72	7	(	(	-LRB-
cord-017772-zpf1xjqi	72	8	schistocytes	schistocytes	NNP
cord-017772-zpf1xjqi	72	9	)	)	-RRB-
cord-017772-zpf1xjqi	72	10	are	be	VBP
cord-017772-zpf1xjqi	72	11	identified	identify	VBN
cord-017772-zpf1xjqi	72	12	by	by	IN
cord-017772-zpf1xjqi	72	13	*	*	NFP
cord-017772-zpf1xjqi	72	14	the	the	DT
cord-017772-zpf1xjqi	72	15	3	3	CD
cord-017772-zpf1xjqi	72	16	major	major	JJ
cord-017772-zpf1xjqi	72	17	anticoagulant	anticoagulant	JJ
cord-017772-zpf1xjqi	72	18	systems	system	NNS
cord-017772-zpf1xjqi	72	19	(	(	-LRB-
cord-017772-zpf1xjqi	72	20	antithrombin	antithrombin	NN
cord-017772-zpf1xjqi	72	21	,	,	,
cord-017772-zpf1xjqi	72	22	the	the	DT
cord-017772-zpf1xjqi	72	23	protein	protein	NN
cord-017772-zpf1xjqi	72	24	C	c	NN
cord-017772-zpf1xjqi	72	25	system	system	NN
cord-017772-zpf1xjqi	72	26	,	,	,
cord-017772-zpf1xjqi	72	27	and	and	CC
cord-017772-zpf1xjqi	72	28	TF	TF	NNP
cord-017772-zpf1xjqi	72	29	pathway	pathway	NN
cord-017772-zpf1xjqi	72	30	inhibitor	inhibitor	NN
cord-017772-zpf1xjqi	72	31	)	)	-RRB-
cord-017772-zpf1xjqi	72	32	are	be	VBP
cord-017772-zpf1xjqi	72	33	dampened	dampen	VBN
cord-017772-zpf1xjqi	72	34	due	due	IN
cord-017772-zpf1xjqi	72	35	to	to	IN
cord-017772-zpf1xjqi	72	36	impaired	impaired	JJ
cord-017772-zpf1xjqi	72	37	synthesis	synthesis	NN
cord-017772-zpf1xjqi	72	38	and	and	CC
cord-017772-zpf1xjqi	72	39	increased	increase	VBN
cord-017772-zpf1xjqi	72	40	degradation	degradation	NN
cord-017772-zpf1xjqi	72	41	of	of	IN
cord-017772-zpf1xjqi	72	42	the	the	DT
cord-017772-zpf1xjqi	72	43	relevant	relevant	JJ
cord-017772-zpf1xjqi	72	44	factors	factor	NNS
cord-017772-zpf1xjqi	72	45	[	[	-LRB-
cord-017772-zpf1xjqi	72	46	32	32	CD
cord-017772-zpf1xjqi	72	47	]	]	-RRB-
cord-017772-zpf1xjqi	72	48	.	.	.
cord-017772-zpf1xjqi	73	1	Finally	finally	RB
cord-017772-zpf1xjqi	73	2	,	,	,
cord-017772-zpf1xjqi	73	3	intrinsic	intrinsic	JJ
cord-017772-zpf1xjqi	73	4	fibrinolysis	fibrinolysis	NN
cord-017772-zpf1xjqi	73	5	is	be	VBZ
cord-017772-zpf1xjqi	73	6	impaired	impair	VBN
cord-017772-zpf1xjqi	73	7	in	in	IN
cord-017772-zpf1xjqi	73	8	part	part	NN
cord-017772-zpf1xjqi	73	9	due	due	IN
cord-017772-zpf1xjqi	73	10	to	to	IN
cord-017772-zpf1xjqi	73	11	elevated	elevated	JJ
cord-017772-zpf1xjqi	73	12	levels	level	NNS
cord-017772-zpf1xjqi	73	13	of	of	IN
cord-017772-zpf1xjqi	73	14	plasminogen	plasminogen	NN
cord-017772-zpf1xjqi	73	15	activator	activator	NN
cord-017772-zpf1xjqi	73	16	inhibitor	inhibitor	NN
cord-017772-zpf1xjqi	73	17	1	1	CD
cord-017772-zpf1xjqi	73	18	.	.	.
cord-017772-zpf1xjqi	74	1	The	the	DT
cord-017772-zpf1xjqi	74	2	propagation	propagation	NN
cord-017772-zpf1xjqi	74	3	of	of	IN
cord-017772-zpf1xjqi	74	4	microvascular	microvascular	JJ
cord-017772-zpf1xjqi	74	5	thrombi	thrombi	NNP
cord-017772-zpf1xjqi	74	6	leads	lead	VBZ
cord-017772-zpf1xjqi	74	7	to	to	IN
cord-017772-zpf1xjqi	74	8	organ	organ	NN
cord-017772-zpf1xjqi	74	9	ischemia	ischemia	NN
cord-017772-zpf1xjqi	74	10	and	and	CC
cord-017772-zpf1xjqi	74	11	dysfunction	dysfunction	NN
cord-017772-zpf1xjqi	74	12	-	-	HYPH
cord-017772-zpf1xjqi	74	13	one	one	CD
cord-017772-zpf1xjqi	74	14	of	of	IN
cord-017772-zpf1xjqi	74	15	the	the	DT
cord-017772-zpf1xjqi	74	16	clinical	clinical	JJ
cord-017772-zpf1xjqi	74	17	hallmarks	hallmark	NNS
cord-017772-zpf1xjqi	74	18	of	of	IN
cord-017772-zpf1xjqi	74	19	DIC	DIC	NNP
cord-017772-zpf1xjqi	74	20	.	.	.
cord-017772-zpf1xjqi	75	1	[	[	-LRB-
cord-017772-zpf1xjqi	75	2	33	33	CD
cord-017772-zpf1xjqi	75	3	]	]	-RRB-
cord-017772-zpf1xjqi	76	1	By	by	IN
cord-017772-zpf1xjqi	76	2	far	far	RB
cord-017772-zpf1xjqi	76	3	,	,	,
cord-017772-zpf1xjqi	76	4	the	the	DT
cord-017772-zpf1xjqi	76	5	most	most	RBS
cord-017772-zpf1xjqi	76	6	common	common	JJ
cord-017772-zpf1xjqi	76	7	underlying	underlying	JJ
cord-017772-zpf1xjqi	76	8	cause	cause	NN
cord-017772-zpf1xjqi	76	9	of	of	IN
cord-017772-zpf1xjqi	76	10	DIC	DIC	NNP
cord-017772-zpf1xjqi	76	11	is	be	VBZ
cord-017772-zpf1xjqi	76	12	sepsis	sepsis	NN
cord-017772-zpf1xjqi	76	13	.	.	.
cord-017772-zpf1xjqi	77	1	Depending	depend	VBG
cord-017772-zpf1xjqi	77	2	on	on	IN
cord-017772-zpf1xjqi	77	3	the	the	DT
cord-017772-zpf1xjqi	77	4	patient	patient	JJ
cord-017772-zpf1xjqi	77	5	population	population	NN
cord-017772-zpf1xjqi	77	6	and	and	CC
cord-017772-zpf1xjqi	77	7	definition	definition	NN
cord-017772-zpf1xjqi	77	8	used	use	VBN
cord-017772-zpf1xjqi	77	9	,	,	,
cord-017772-zpf1xjqi	77	10	25	25	CD
cord-017772-zpf1xjqi	77	11	-	-	SYM
cord-017772-zpf1xjqi	77	12	60	60	CD
cord-017772-zpf1xjqi	77	13	%	%	NN
cord-017772-zpf1xjqi	77	14	of	of	IN
cord-017772-zpf1xjqi	77	15	patients	patient	NNS
cord-017772-zpf1xjqi	77	16	with	with	IN
cord-017772-zpf1xjqi	77	17	sepsis	sepsis	NN
cord-017772-zpf1xjqi	77	18	develop	develop	VB
cord-017772-zpf1xjqi	77	19	DIC	DIC	NNP
cord-017772-zpf1xjqi	77	20	[	[	-LRB-
cord-017772-zpf1xjqi	77	21	32	32	CD
cord-017772-zpf1xjqi	77	22	,	,	,
cord-017772-zpf1xjqi	77	23	34	34	CD
cord-017772-zpf1xjqi	77	24	,	,	,
cord-017772-zpf1xjqi	77	25	35	35	CD
cord-017772-zpf1xjqi	77	26	]	]	-RRB-
cord-017772-zpf1xjqi	77	27	.	.	.
cord-017772-zpf1xjqi	78	1	In	in	IN
cord-017772-zpf1xjqi	78	2	cases	case	NNS
cord-017772-zpf1xjqi	78	3	series	series	NN
cord-017772-zpf1xjqi	78	4	,	,	,
cord-017772-zpf1xjqi	78	5	sepsis	sepsis	NN
cord-017772-zpf1xjqi	78	6	is	be	VBZ
cord-017772-zpf1xjqi	78	7	identified	identify	VBN
cord-017772-zpf1xjqi	78	8	as	as	IN
cord-017772-zpf1xjqi	78	9	a	a	DT
cord-017772-zpf1xjqi	78	10	risk	risk	NN
cord-017772-zpf1xjqi	78	11	factor	factor	NN
cord-017772-zpf1xjqi	78	12	for	for	IN
cord-017772-zpf1xjqi	78	13	DIC	DIC	NNP
cord-017772-zpf1xjqi	78	14	in	in	RB
cord-017772-zpf1xjqi	78	15	over	over	IN
cord-017772-zpf1xjqi	78	16	50	50	CD
cord-017772-zpf1xjqi	78	17	%	%	NN
cord-017772-zpf1xjqi	78	18	of	of	IN
cord-017772-zpf1xjqi	78	19	patients	patient	NNS
cord-017772-zpf1xjqi	78	20	[	[	-LRB-
cord-017772-zpf1xjqi	78	21	36	36	CD
cord-017772-zpf1xjqi	78	22	]	]	-RRB-
cord-017772-zpf1xjqi	78	23	.	.	.
cord-017772-zpf1xjqi	79	1	Other	other	JJ
cord-017772-zpf1xjqi	79	2	important	important	JJ
cord-017772-zpf1xjqi	79	3	causes	cause	NNS
cord-017772-zpf1xjqi	79	4	of	of	IN
cord-017772-zpf1xjqi	79	5	DIC	DIC	NNP
cord-017772-zpf1xjqi	79	6	include	include	VBP
cord-017772-zpf1xjqi	79	7	trauma	trauma	NN
cord-017772-zpf1xjqi	79	8	,	,	,
cord-017772-zpf1xjqi	79	9	obstetric	obstetric	JJ
cord-017772-zpf1xjqi	79	10	emergencies	emergency	NNS
cord-017772-zpf1xjqi	79	11	,	,	,
cord-017772-zpf1xjqi	79	12	malignancies	malignancy	NNS
cord-017772-zpf1xjqi	79	13	,	,	,
cord-017772-zpf1xjqi	79	14	and	and	CC
cord-017772-zpf1xjqi	79	15	liver	liver	NN
cord-017772-zpf1xjqi	79	16	failure	failure	NN
cord-017772-zpf1xjqi	79	17	among	among	IN
cord-017772-zpf1xjqi	79	18	many	many	JJ
cord-017772-zpf1xjqi	79	19	others	other	NNS
cord-017772-zpf1xjqi	79	20	[	[	-LRB-
cord-017772-zpf1xjqi	79	21	32	32	CD
cord-017772-zpf1xjqi	79	22	]	]	-RRB-
cord-017772-zpf1xjqi	79	23	.	.	.
cord-017772-zpf1xjqi	80	1	DIC	DIC	NNP
cord-017772-zpf1xjqi	80	2	is	be	VBZ
cord-017772-zpf1xjqi	80	3	consistently	consistently	RB
cord-017772-zpf1xjqi	80	4	identified	identify	VBN
cord-017772-zpf1xjqi	80	5	as	as	IN
cord-017772-zpf1xjqi	80	6	a	a	DT
cord-017772-zpf1xjqi	80	7	risk	risk	NN
cord-017772-zpf1xjqi	80	8	factor	factor	NN
cord-017772-zpf1xjqi	80	9	for	for	IN
cord-017772-zpf1xjqi	80	10	increased	increase	VBN
cord-017772-zpf1xjqi	80	11	mortality	mortality	NN
cord-017772-zpf1xjqi	80	12	both	both	CC
cord-017772-zpf1xjqi	80	13	in	in	IN
cord-017772-zpf1xjqi	80	14	patients	patient	NNS
cord-017772-zpf1xjqi	80	15	with	with	IN
cord-017772-zpf1xjqi	80	16	sepsis	sepsis	NN
cord-017772-zpf1xjqi	80	17	and	and	CC
cord-017772-zpf1xjqi	80	18	in	in	IN
cord-017772-zpf1xjqi	80	19	critically	critically	RB
cord-017772-zpf1xjqi	80	20	ill	ill	JJ
cord-017772-zpf1xjqi	80	21	patients	patient	NNS
cord-017772-zpf1xjqi	80	22	more	more	RBR
cord-017772-zpf1xjqi	80	23	broadly	broadly	RB
cord-017772-zpf1xjqi	80	24	[	[	-LRB-
cord-017772-zpf1xjqi	80	25	34	34	CD
cord-017772-zpf1xjqi	80	26	,	,	,
cord-017772-zpf1xjqi	80	27	36	36	CD
cord-017772-zpf1xjqi	80	28	,	,	,
cord-017772-zpf1xjqi	80	29	37	37	CD
cord-017772-zpf1xjqi	80	30	]	]	-RRB-
cord-017772-zpf1xjqi	80	31	.	.	.
cord-017772-zpf1xjqi	81	1	The	the	DT
cord-017772-zpf1xjqi	81	2	diagnosis	diagnosis	NN
cord-017772-zpf1xjqi	81	3	of	of	IN
cord-017772-zpf1xjqi	81	4	DIC	DIC	NNP
cord-017772-zpf1xjqi	81	5	should	should	MD
cord-017772-zpf1xjqi	81	6	be	be	VB
cord-017772-zpf1xjqi	81	7	suspected	suspect	VBN
cord-017772-zpf1xjqi	81	8	in	in	IN
cord-017772-zpf1xjqi	81	9	any	any	DT
cord-017772-zpf1xjqi	81	10	critically	critically	RB
cord-017772-zpf1xjqi	81	11	ill	ill	JJ
cord-017772-zpf1xjqi	81	12	patient	patient	NN
cord-017772-zpf1xjqi	81	13	with	with	IN
cord-017772-zpf1xjqi	81	14	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	81	15	,	,	,
cord-017772-zpf1xjqi	81	16	abnormal	abnormal	JJ
cord-017772-zpf1xjqi	81	17	coagulation	coagulation	NN
cord-017772-zpf1xjqi	81	18	parameters	parameter	NNS
cord-017772-zpf1xjqi	81	19	(	(	-LRB-
cord-017772-zpf1xjqi	81	20	e.g.	e.g.	RB
cord-017772-zpf1xjqi	81	21	,	,	,
cord-017772-zpf1xjqi	81	22	a	a	DT
cord-017772-zpf1xjqi	81	23	prolonged	prolonged	JJ
cord-017772-zpf1xjqi	81	24	prothrombin	prothrombin	NN
cord-017772-zpf1xjqi	81	25	and	and	CC
cord-017772-zpf1xjqi	81	26	partial	partial	JJ
cord-017772-zpf1xjqi	81	27	thromboplastin	thromboplastin	NNP
cord-017772-zpf1xjqi	81	28	times	time	NNS
cord-017772-zpf1xjqi	81	29	)	)	-RRB-
cord-017772-zpf1xjqi	81	30	,	,	,
cord-017772-zpf1xjqi	81	31	MAHA	MAHA	NNP
cord-017772-zpf1xjqi	81	32	,	,	,
cord-017772-zpf1xjqi	81	33	and	and	CC
cord-017772-zpf1xjqi	81	34	laboratory	laboratory	NN
cord-017772-zpf1xjqi	81	35	evidence	evidence	NN
cord-017772-zpf1xjqi	81	36	of	of	IN
cord-017772-zpf1xjqi	81	37	fibrinolysis	fibrinolysis	NN
cord-017772-zpf1xjqi	81	38	(	(	-LRB-
cord-017772-zpf1xjqi	81	39	e.g.	e.g.	RB
cord-017772-zpf1xjqi	81	40	,	,	,
cord-017772-zpf1xjqi	81	41	an	an	DT
cord-017772-zpf1xjqi	81	42	elevated	elevated	JJ
cord-017772-zpf1xjqi	81	43	d	d	NN
cord-017772-zpf1xjqi	81	44	-	-	HYPH
cord-017772-zpf1xjqi	81	45	dimer	dimer	JJ
cord-017772-zpf1xjqi	81	46	and	and	CC
cord-017772-zpf1xjqi	81	47	reduced	reduced	JJ
cord-017772-zpf1xjqi	81	48	fibrinogen	fibrinogen	NN
cord-017772-zpf1xjqi	81	49	)	)	-RRB-
cord-017772-zpf1xjqi	81	50	[	[	-LRB-
cord-017772-zpf1xjqi	81	51	38	38	CD
cord-017772-zpf1xjqi	81	52	]	]	-RRB-
cord-017772-zpf1xjqi	81	53	.	.	.
cord-017772-zpf1xjqi	82	1	While	while	IN
cord-017772-zpf1xjqi	82	2	catastrophic	catastrophic	JJ
cord-017772-zpf1xjqi	82	3	hemorrhage	hemorrhage	NN
cord-017772-zpf1xjqi	82	4	is	be	VBZ
cord-017772-zpf1xjqi	82	5	uncommon	uncommon	JJ
cord-017772-zpf1xjqi	82	6	,	,	,
cord-017772-zpf1xjqi	82	7	most	most	JJS
cord-017772-zpf1xjqi	82	8	patients	patient	NNS
cord-017772-zpf1xjqi	82	9	have	have	VBP
cord-017772-zpf1xjqi	82	10	evidence	evidence	NN
cord-017772-zpf1xjqi	82	11	of	of	IN
cord-017772-zpf1xjqi	82	12	bleeding	bleed	VBG
cord-017772-zpf1xjqi	82	13	,	,	,
cord-017772-zpf1xjqi	82	14	often	often	RB
cord-017772-zpf1xjqi	82	15	at	at	IN
cord-017772-zpf1xjqi	82	16	sites	site	NNS
cord-017772-zpf1xjqi	82	17	of	of	IN
cord-017772-zpf1xjqi	82	18	intravenous	intravenous	JJ
cord-017772-zpf1xjqi	82	19	access	access	NN
cord-017772-zpf1xjqi	82	20	[	[	-LRB-
cord-017772-zpf1xjqi	82	21	33	33	CD
cord-017772-zpf1xjqi	82	22	]	]	-RRB-
cord-017772-zpf1xjqi	82	23	.	.	.
cord-017772-zpf1xjqi	83	1	Diagnostic	diagnostic	JJ
cord-017772-zpf1xjqi	83	2	criteria	criterion	NNS
cord-017772-zpf1xjqi	83	3	developed	develop	VBN
cord-017772-zpf1xjqi	83	4	by	by	IN
cord-017772-zpf1xjqi	83	5	the	the	DT
cord-017772-zpf1xjqi	83	6	ISTH	ISTH	NNP
cord-017772-zpf1xjqi	83	7	are	be	VBP
cord-017772-zpf1xjqi	83	8	available	available	JJ
cord-017772-zpf1xjqi	83	9	to	to	TO
cord-017772-zpf1xjqi	83	10	aid	aid	VB
cord-017772-zpf1xjqi	83	11	diagnosis	diagnosis	NN
cord-017772-zpf1xjqi	83	12	(	(	-LRB-
cord-017772-zpf1xjqi	83	13	Table	table	NN
cord-017772-zpf1xjqi	83	14	83	83	CD
cord-017772-zpf1xjqi	83	15	.1	.1	CD
cord-017772-zpf1xjqi	83	16	)	)	-RRB-
cord-017772-zpf1xjqi	84	1	[	[	-LRB-
cord-017772-zpf1xjqi	84	2	37	37	CD
cord-017772-zpf1xjqi	84	3	]	]	-RRB-
cord-017772-zpf1xjqi	84	4	.	.	.
cord-017772-zpf1xjqi	85	1	In	in	IN
cord-017772-zpf1xjqi	85	2	a	a	DT
cord-017772-zpf1xjqi	85	3	prospective	prospective	JJ
cord-017772-zpf1xjqi	85	4	validation	validation	NN
cord-017772-zpf1xjqi	85	5	study	study	NN
cord-017772-zpf1xjqi	85	6	,	,	,
cord-017772-zpf1xjqi	85	7	a	a	DT
cord-017772-zpf1xjqi	85	8	score	score	NN
cord-017772-zpf1xjqi	85	9	>	>	XX
cord-017772-zpf1xjqi	86	1	5	5	CD
cord-017772-zpf1xjqi	86	2	had	have	VBD
cord-017772-zpf1xjqi	86	3	a	a	DT
cord-017772-zpf1xjqi	86	4	sensitivity	sensitivity	NN
cord-017772-zpf1xjqi	86	5	of	of	IN
cord-017772-zpf1xjqi	86	6	91	91	CD
cord-017772-zpf1xjqi	86	7	%	%	NN
cord-017772-zpf1xjqi	86	8	and	and	CC
cord-017772-zpf1xjqi	86	9	specificity	specificity	NN
cord-017772-zpf1xjqi	86	10	of	of	IN
cord-017772-zpf1xjqi	86	11	97	97	CD
cord-017772-zpf1xjqi	86	12	%	%	NN
cord-017772-zpf1xjqi	86	13	for	for	IN
cord-017772-zpf1xjqi	86	14	the	the	DT
cord-017772-zpf1xjqi	86	15	diagnosis	diagnosis	NN
cord-017772-zpf1xjqi	86	16	of	of	IN
cord-017772-zpf1xjqi	86	17	DIC	DIC	NNP
cord-017772-zpf1xjqi	86	18	[	[	-LRB-
cord-017772-zpf1xjqi	86	19	39	39	CD
cord-017772-zpf1xjqi	86	20	]	]	-RRB-
cord-017772-zpf1xjqi	86	21	.	.	.
cord-017772-zpf1xjqi	87	1	A	a	DT
cord-017772-zpf1xjqi	87	2	score	score	NN
cord-017772-zpf1xjqi	87	3	should	should	MD
cord-017772-zpf1xjqi	87	4	be	be	VB
cord-017772-zpf1xjqi	87	5	calculated	calculate	VBN
cord-017772-zpf1xjqi	87	6	daily	daily	RB
cord-017772-zpf1xjqi	87	7	both	both	DT
cord-017772-zpf1xjqi	87	8	to	to	TO
cord-017772-zpf1xjqi	87	9	accurately	accurately	RB
cord-017772-zpf1xjqi	87	10	confirm	confirm	VB
cord-017772-zpf1xjqi	87	11	the	the	DT
cord-017772-zpf1xjqi	87	12	diagnosis	diagnosis	NN
cord-017772-zpf1xjqi	87	13	and	and	CC
cord-017772-zpf1xjqi	87	14	to	to	TO
cord-017772-zpf1xjqi	87	15	aid	aid	VB
cord-017772-zpf1xjqi	87	16	prognostication	prognostication	NN
cord-017772-zpf1xjqi	87	17	[	[	-LRB-
cord-017772-zpf1xjqi	87	18	40	40	CD
cord-017772-zpf1xjqi	87	19	]	]	-RRB-
cord-017772-zpf1xjqi	87	20	.	.	.
cord-017772-zpf1xjqi	88	1	The	the	DT
cord-017772-zpf1xjqi	88	2	foundation	foundation	NN
cord-017772-zpf1xjqi	88	3	of	of	IN
cord-017772-zpf1xjqi	88	4	DIC	DIC	NNP
cord-017772-zpf1xjqi	88	5	management	management	NN
cord-017772-zpf1xjqi	88	6	is	be	VBZ
cord-017772-zpf1xjqi	88	7	treatment	treatment	NN
cord-017772-zpf1xjqi	88	8	of	of	IN
cord-017772-zpf1xjqi	88	9	the	the	DT
cord-017772-zpf1xjqi	88	10	underlying	underlying	JJ
cord-017772-zpf1xjqi	88	11	disorder	disorder	NN
cord-017772-zpf1xjqi	88	12	.	.	.
cord-017772-zpf1xjqi	89	1	There	there	EX
cord-017772-zpf1xjqi	89	2	is	be	VBZ
cord-017772-zpf1xjqi	89	3	limited	limited	JJ
cord-017772-zpf1xjqi	89	4	data	datum	NNS
cord-017772-zpf1xjqi	89	5	to	to	TO
cord-017772-zpf1xjqi	89	6	guide	guide	VB
cord-017772-zpf1xjqi	89	7	the	the	DT
cord-017772-zpf1xjqi	89	8	administration	administration	NN
cord-017772-zpf1xjqi	89	9	of	of	IN
cord-017772-zpf1xjqi	89	10	blood	blood	NN
cord-017772-zpf1xjqi	89	11	products	product	NNS
cord-017772-zpf1xjqi	89	12	in	in	IN
cord-017772-zpf1xjqi	89	13	DIC	DIC	NNP
cord-017772-zpf1xjqi	89	14	.	.	.
cord-017772-zpf1xjqi	90	1	In	in	IN
cord-017772-zpf1xjqi	90	2	general	general	JJ
cord-017772-zpf1xjqi	90	3	,	,	,
cord-017772-zpf1xjqi	90	4	guidelines	guideline	NNS
cord-017772-zpf1xjqi	90	5	agree	agree	VBP
cord-017772-zpf1xjqi	90	6	that	that	IN
cord-017772-zpf1xjqi	90	7	platelets	platelet	NNS
cord-017772-zpf1xjqi	90	8	,	,	,
cord-017772-zpf1xjqi	90	9	fresh	fresh	RB
cord-017772-zpf1xjqi	90	10	-	-	HYPH
cord-017772-zpf1xjqi	90	11	frozen	frozen	JJ
cord-017772-zpf1xjqi	90	12	plasma	plasma	NN
cord-017772-zpf1xjqi	90	13	,	,	,
cord-017772-zpf1xjqi	90	14	and	and	CC
cord-017772-zpf1xjqi	90	15	a	a	DT
cord-017772-zpf1xjqi	90	16	source	source	NN
cord-017772-zpf1xjqi	90	17	of	of	IN
cord-017772-zpf1xjqi	90	18	fibrinogen	fibrinogen	NN
cord-017772-zpf1xjqi	90	19	should	should	MD
cord-017772-zpf1xjqi	90	20	be	be	VB
cord-017772-zpf1xjqi	90	21	given	give	VBN
cord-017772-zpf1xjqi	90	22	to	to	IN
cord-017772-zpf1xjqi	90	23	patients	patient	NNS
cord-017772-zpf1xjqi	90	24	who	who	WP
cord-017772-zpf1xjqi	90	25	are	be	VBP
cord-017772-zpf1xjqi	90	26	actively	actively	RB
cord-017772-zpf1xjqi	90	27	bleeding	bleed	VBG
cord-017772-zpf1xjqi	90	28	or	or	CC
cord-017772-zpf1xjqi	90	29	those	those	DT
cord-017772-zpf1xjqi	90	30	undergoing	undergo	VBG
cord-017772-zpf1xjqi	90	31	invasive	invasive	JJ
cord-017772-zpf1xjqi	90	32	procedures	procedure	NNS
cord-017772-zpf1xjqi	90	33	[	[	-LRB-
cord-017772-zpf1xjqi	90	34	41	41	CD
cord-017772-zpf1xjqi	90	35	]	]	-RRB-
cord-017772-zpf1xjqi	90	36	.	.	.
cord-017772-zpf1xjqi	91	1	A	a	DT
cord-017772-zpf1xjqi	91	2	platelet	platelet	NN
cord-017772-zpf1xjqi	91	3	count	count	NN
cord-017772-zpf1xjqi	91	4	>	>	XX
cord-017772-zpf1xjqi	91	5	50	50	CD
cord-017772-zpf1xjqi	91	6	×	×	NN
cord-017772-zpf1xjqi	91	7	10	10	CD
cord-017772-zpf1xjqi	91	8	9	9	CD
cord-017772-zpf1xjqi	91	9	cells	cell	NNS
cord-017772-zpf1xjqi	91	10	/	/	SYM
cord-017772-zpf1xjqi	91	11	L	l	NN
cord-017772-zpf1xjqi	91	12	,	,	,
cord-017772-zpf1xjqi	91	13	prothrombin	prothrombin	NN
cord-017772-zpf1xjqi	91	14	(	(	-LRB-
cord-017772-zpf1xjqi	91	15	PT	pt	NN
cord-017772-zpf1xjqi	91	16	)	)	-RRB-
cord-017772-zpf1xjqi	92	1	and	and	CC
cord-017772-zpf1xjqi	92	2	partial	partial	JJ
cord-017772-zpf1xjqi	92	3	thromboplastin	thromboplastin	NNP
cord-017772-zpf1xjqi	92	4	time	time	NN
cord-017772-zpf1xjqi	92	5	(	(	-LRB-
cord-017772-zpf1xjqi	92	6	aPTT	aptt	NN
cord-017772-zpf1xjqi	92	7	)	)	-RRB-
cord-017772-zpf1xjqi	92	8	<	<	XX
cord-017772-zpf1xjqi	92	9	1.5	1.5	CD
cord-017772-zpf1xjqi	92	10	times	time	NNS
cord-017772-zpf1xjqi	92	11	normal	normal	JJ
cord-017772-zpf1xjqi	92	12	,	,	,
cord-017772-zpf1xjqi	92	13	and	and	CC
cord-017772-zpf1xjqi	92	14	a	a	DT
cord-017772-zpf1xjqi	92	15	fibrinogen	fibrinogen	NN
cord-017772-zpf1xjqi	92	16	level	level	NN
cord-017772-zpf1xjqi	92	17	>	>	XX
cord-017772-zpf1xjqi	93	1	1.5	1.5	CD
cord-017772-zpf1xjqi	93	2	g	g	NN
cord-017772-zpf1xjqi	93	3	/	/	SYM
cord-017772-zpf1xjqi	93	4	L	L	NNP
cord-017772-zpf1xjqi	93	5	are	be	VBP
cord-017772-zpf1xjqi	93	6	typical	typical	JJ
cord-017772-zpf1xjqi	93	7	targets	target	NNS
cord-017772-zpf1xjqi	93	8	[	[	-LRB-
cord-017772-zpf1xjqi	93	9	19	19	CD
cord-017772-zpf1xjqi	93	10	]	]	-RRB-
cord-017772-zpf1xjqi	93	11	.	.	.
cord-017772-zpf1xjqi	94	1	Recommendations	recommendation	NNS
cord-017772-zpf1xjqi	94	2	for	for	IN
cord-017772-zpf1xjqi	94	3	the	the	DT
cord-017772-zpf1xjqi	94	4	use	use	NN
cord-017772-zpf1xjqi	94	5	of	of	IN
cord-017772-zpf1xjqi	94	6	heparin	heparin	NN
cord-017772-zpf1xjqi	94	7	vary	vary	VBP
cord-017772-zpf1xjqi	94	8	across	across	IN
cord-017772-zpf1xjqi	94	9	guidelines	guideline	NNS
cord-017772-zpf1xjqi	94	10	[	[	-LRB-
cord-017772-zpf1xjqi	94	11	41	41	CD
cord-017772-zpf1xjqi	94	12	]	]	-RRB-
cord-017772-zpf1xjqi	94	13	.	.	.
cord-017772-zpf1xjqi	95	1	In	in	IN
cord-017772-zpf1xjqi	95	2	general	general	JJ
cord-017772-zpf1xjqi	95	3	,	,	,
cord-017772-zpf1xjqi	95	4	heparin	heparin	NNP
cord-017772-zpf1xjqi	95	5	is	be	VBZ
cord-017772-zpf1xjqi	95	6	reserved	reserve	VBN
cord-017772-zpf1xjqi	95	7	for	for	IN
cord-017772-zpf1xjqi	95	8	patients	patient	NNS
cord-017772-zpf1xjqi	95	9	with	with	IN
cord-017772-zpf1xjqi	95	10	clinical	clinical	JJ
cord-017772-zpf1xjqi	95	11	evidence	evidence	NN
cord-017772-zpf1xjqi	95	12	of	of	IN
cord-017772-zpf1xjqi	95	13	thrombosis	thrombosis	NN
cord-017772-zpf1xjqi	95	14	.	.	.
cord-017772-zpf1xjqi	96	1	A	a	DT
cord-017772-zpf1xjqi	96	2	host	host	NN
cord-017772-zpf1xjqi	96	3	of	of	IN
cord-017772-zpf1xjqi	96	4	targeted	target	VBN
cord-017772-zpf1xjqi	96	5	interventions	intervention	NNS
cord-017772-zpf1xjqi	96	6	aimed	aim	VBN
cord-017772-zpf1xjqi	96	7	at	at	IN
cord-017772-zpf1xjqi	96	8	augmenting	augment	VBG
cord-017772-zpf1xjqi	96	9	the	the	DT
cord-017772-zpf1xjqi	96	10	major	major	JJ
cord-017772-zpf1xjqi	96	11	anticoagulant	anticoagulant	JJ
cord-017772-zpf1xjqi	96	12	pathways	pathway	NNS
cord-017772-zpf1xjqi	96	13	have	have	VBP
cord-017772-zpf1xjqi	96	14	failed	fail	VBN
cord-017772-zpf1xjqi	96	15	to	to	TO
cord-017772-zpf1xjqi	96	16	show	show	VB
cord-017772-zpf1xjqi	96	17	benefit	benefit	NN
cord-017772-zpf1xjqi	96	18	in	in	IN
cord-017772-zpf1xjqi	96	19	large	large	JJ
cord-017772-zpf1xjqi	96	20	randomized	randomized	JJ
cord-017772-zpf1xjqi	96	21	trials	trial	NNS
cord-017772-zpf1xjqi	96	22	including	include	VBG
cord-017772-zpf1xjqi	96	23	recombinant	recombinant	JJ
cord-017772-zpf1xjqi	96	24	TF	TF	NNP
cord-017772-zpf1xjqi	96	25	pathway	pathway	NN
cord-017772-zpf1xjqi	96	26	inhibitors	inhibitor	NNS
cord-017772-zpf1xjqi	96	27	and	and	CC
cord-017772-zpf1xjqi	96	28	anti	anti	JJ
cord-017772-zpf1xjqi	96	29	-	-	JJ
cord-017772-zpf1xjqi	96	30	thrombin	thrombin	JJ
cord-017772-zpf1xjqi	96	31	III	III	NNP
cord-017772-zpf1xjqi	96	32	[	[	-LRB-
cord-017772-zpf1xjqi	96	33	42	42	CD
cord-017772-zpf1xjqi	96	34	,	,	,
cord-017772-zpf1xjqi	96	35	43	43	CD
cord-017772-zpf1xjqi	96	36	]	]	-RRB-
cord-017772-zpf1xjqi	96	37	.	.	.
cord-017772-zpf1xjqi	97	1	Early	early	JJ
cord-017772-zpf1xjqi	97	2	studies	study	NNS
cord-017772-zpf1xjqi	97	3	of	of	IN
cord-017772-zpf1xjqi	97	4	activated	activate	VBN
cord-017772-zpf1xjqi	97	5	protein	protein	NN
cord-017772-zpf1xjqi	97	6	C	C	NNP
cord-017772-zpf1xjqi	97	7	(	(	-LRB-
cord-017772-zpf1xjqi	97	8	APC	APC	NNP
cord-017772-zpf1xjqi	97	9	)	)	-RRB-
cord-017772-zpf1xjqi	97	10	in	in	IN
cord-017772-zpf1xjqi	97	11	patients	patient	NNS
cord-017772-zpf1xjqi	97	12	with	with	IN
cord-017772-zpf1xjqi	97	13	sepsis	sepsis	NN
cord-017772-zpf1xjqi	97	14	showed	show	VBD
cord-017772-zpf1xjqi	97	15	promise	promise	NN
cord-017772-zpf1xjqi	97	16	,	,	,
cord-017772-zpf1xjqi	97	17	especially	especially	RB
cord-017772-zpf1xjqi	97	18	in	in	IN
cord-017772-zpf1xjqi	97	19	the	the	DT
cord-017772-zpf1xjqi	97	20	subset	subset	NN
cord-017772-zpf1xjqi	97	21	of	of	IN
cord-017772-zpf1xjqi	97	22	patients	patient	NNS
cord-017772-zpf1xjqi	97	23	with	with	IN
cord-017772-zpf1xjqi	97	24	DIC	DIC	NNP
cord-017772-zpf1xjqi	97	25	[	[	-LRB-
cord-017772-zpf1xjqi	97	26	44	44	CD
cord-017772-zpf1xjqi	97	27	,	,	,
cord-017772-zpf1xjqi	97	28	45	45	CD
cord-017772-zpf1xjqi	97	29	]	]	-RRB-
cord-017772-zpf1xjqi	97	30	.	.	.
cord-017772-zpf1xjqi	98	1	However	however	RB
cord-017772-zpf1xjqi	98	2	,	,	,
cord-017772-zpf1xjqi	98	3	the	the	DT
cord-017772-zpf1xjqi	98	4	recent	recent	JJ
cord-017772-zpf1xjqi	98	5	PROWESS	prowess	NN
cord-017772-zpf1xjqi	98	6	-	-	HYPH
cord-017772-zpf1xjqi	98	7	SHOCK	shock	NN
cord-017772-zpf1xjqi	98	8	trial	trial	NN
cord-017772-zpf1xjqi	98	9	,	,	,
cord-017772-zpf1xjqi	98	10	which	which	WDT
cord-017772-zpf1xjqi	98	11	included	include	VBD
cord-017772-zpf1xjqi	98	12	over	over	IN
cord-017772-zpf1xjqi	98	13	1500	1500	CD
cord-017772-zpf1xjqi	98	14	patients	patient	NNS
cord-017772-zpf1xjqi	98	15	with	with	IN
cord-017772-zpf1xjqi	98	16	septic	septic	JJ
cord-017772-zpf1xjqi	98	17	shock	shock	NN
cord-017772-zpf1xjqi	98	18	,	,	,
cord-017772-zpf1xjqi	98	19	did	do	VBD
cord-017772-zpf1xjqi	98	20	not	not	RB
cord-017772-zpf1xjqi	98	21	identify	identify	VB
cord-017772-zpf1xjqi	98	22	any	any	DT
cord-017772-zpf1xjqi	98	23	benefit	benefit	NN
cord-017772-zpf1xjqi	98	24	to	to	IN
cord-017772-zpf1xjqi	98	25	the	the	DT
cord-017772-zpf1xjqi	98	26	use	use	NN
cord-017772-zpf1xjqi	98	27	of	of	IN
cord-017772-zpf1xjqi	98	28	APC	APC	NNP
cord-017772-zpf1xjqi	98	29	[	[	-LRB-
cord-017772-zpf1xjqi	98	30	46	46	CD
cord-017772-zpf1xjqi	98	31	]	]	-RRB-
cord-017772-zpf1xjqi	98	32	.	.	.
cord-017772-zpf1xjqi	99	1	A	a	DT
cord-017772-zpf1xjqi	99	2	careful	careful	JJ
cord-017772-zpf1xjqi	99	3	review	review	NN
cord-017772-zpf1xjqi	99	4	of	of	IN
cord-017772-zpf1xjqi	99	5	a	a	DT
cord-017772-zpf1xjqi	99	6	patient	patient	NN
cord-017772-zpf1xjqi	99	7	's	's	POS
cord-017772-zpf1xjqi	99	8	medication	medication	NN
cord-017772-zpf1xjqi	99	9	list	list	NN
cord-017772-zpf1xjqi	99	10	is	be	VBZ
cord-017772-zpf1xjqi	99	11	an	an	DT
cord-017772-zpf1xjqi	99	12	essential	essential	JJ
cord-017772-zpf1xjqi	99	13	step	step	NN
cord-017772-zpf1xjqi	99	14	in	in	IN
cord-017772-zpf1xjqi	99	15	the	the	DT
cord-017772-zpf1xjqi	99	16	evaluation	evaluation	NN
cord-017772-zpf1xjqi	99	17	of	of	IN
cord-017772-zpf1xjqi	99	18	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	99	19	in	in	IN
cord-017772-zpf1xjqi	99	20	the	the	DT
cord-017772-zpf1xjqi	99	21	ICU	ICU	NNP
cord-017772-zpf1xjqi	99	22	.	.	.
cord-017772-zpf1xjqi	100	1	Indeed	indeed	RB
cord-017772-zpf1xjqi	100	2	,	,	,
cord-017772-zpf1xjqi	100	3	medications	medication	NNS
cord-017772-zpf1xjqi	100	4	may	may	MD
cord-017772-zpf1xjqi	100	5	contribute	contribute	VB
cord-017772-zpf1xjqi	100	6	to	to	IN
cord-017772-zpf1xjqi	100	7	over	over	IN
cord-017772-zpf1xjqi	100	8	10	10	CD
cord-017772-zpf1xjqi	100	9	%	%	NN
cord-017772-zpf1xjqi	100	10	of	of	IN
cord-017772-zpf1xjqi	100	11	new	new	JJ
cord-017772-zpf1xjqi	100	12	onset	onset	NN
cord-017772-zpf1xjqi	100	13	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	100	14	in	in	IN
cord-017772-zpf1xjqi	100	15	the	the	DT
cord-017772-zpf1xjqi	100	16	critically	critically	RB
cord-017772-zpf1xjqi	100	17	ill	ill	JJ
cord-017772-zpf1xjqi	100	18	[	[	-LRB-
cord-017772-zpf1xjqi	100	19	17	17	CD
cord-017772-zpf1xjqi	100	20	]	]	-RRB-
cord-017772-zpf1xjqi	100	21	.	.	.
cord-017772-zpf1xjqi	101	1	Well	well	UH
cord-017772-zpf1xjqi	101	2	over	over	IN
cord-017772-zpf1xjqi	101	3	300	300	CD
cord-017772-zpf1xjqi	101	4	drugs	drug	NNS
cord-017772-zpf1xjqi	101	5	have	have	VBP
cord-017772-zpf1xjqi	101	6	been	be	VBN
cord-017772-zpf1xjqi	101	7	linked	link	VBN
cord-017772-zpf1xjqi	101	8	to	to	IN
cord-017772-zpf1xjqi	101	9	the	the	DT
cord-017772-zpf1xjqi	101	10	development	development	NN
cord-017772-zpf1xjqi	101	11	of	of	IN
cord-017772-zpf1xjqi	101	12	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	101	13	[	[	-LRB-
cord-017772-zpf1xjqi	101	14	47	47	CD
cord-017772-zpf1xjqi	101	15	]	]	-RRB-
cord-017772-zpf1xjqi	101	16	.	.	.
cord-017772-zpf1xjqi	102	1	A	a	DT
cord-017772-zpf1xjqi	102	2	list	list	NN
cord-017772-zpf1xjqi	102	3	of	of	IN
cord-017772-zpf1xjqi	102	4	notable	notable	JJ
cord-017772-zpf1xjqi	102	5	drugs	drug	NNS
cord-017772-zpf1xjqi	102	6	known	know	VBN
cord-017772-zpf1xjqi	102	7	to	to	TO
cord-017772-zpf1xjqi	102	8	cause	cause	VB
cord-017772-zpf1xjqi	102	9	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	102	10	is	be	VBZ
cord-017772-zpf1xjqi	102	11	provided	provide	VBN
cord-017772-zpf1xjqi	102	12	in	in	IN
cord-017772-zpf1xjqi	102	13	Table	Table	NNP
cord-017772-zpf1xjqi	102	14	83.2	83.2	CD
cord-017772-zpf1xjqi	102	15	.	.	.
cord-017772-zpf1xjqi	103	1	Drug	drug	NN
cord-017772-zpf1xjqi	103	2	-	-	HYPH
cord-017772-zpf1xjqi	103	3	induced	induce	VBN
cord-017772-zpf1xjqi	103	4	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	103	5	can	can	MD
cord-017772-zpf1xjqi	103	6	be	be	VB
cord-017772-zpf1xjqi	103	7	grouped	group	VBN
cord-017772-zpf1xjqi	103	8	into	into	IN
cord-017772-zpf1xjqi	103	9	two	two	CD
cord-017772-zpf1xjqi	103	10	major	major	JJ
cord-017772-zpf1xjqi	103	11	categories	category	NNS
cord-017772-zpf1xjqi	103	12	:	:	:
cord-017772-zpf1xjqi	103	13	drug	drug	NN
cord-017772-zpf1xjqi	103	14	-	-	HYPH
cord-017772-zpf1xjqi	103	15	induced	induce	VBN
cord-017772-zpf1xjqi	103	16	non	non	JJ
cord-017772-zpf1xjqi	103	17	-	-	JJ
cord-017772-zpf1xjqi	103	18	immune	immune	JJ
cord-017772-zpf1xjqi	103	19	Adapted	adapt	VBN
cord-017772-zpf1xjqi	103	20	from	from	IN
cord-017772-zpf1xjqi	103	21	Toh	Toh	NNP
cord-017772-zpf1xjqi	103	22	[	[	-LRB-
cord-017772-zpf1xjqi	103	23	37	37	CD
cord-017772-zpf1xjqi	103	24	]	]	-RRB-
cord-017772-zpf1xjqi	103	25	.	.	.
cord-017772-zpf1xjqi	104	1	A	a	DT
cord-017772-zpf1xjqi	104	2	score	score	NN
cord-017772-zpf1xjqi	104	3	of	of	IN
cord-017772-zpf1xjqi	104	4	>	>	XX
cord-017772-zpf1xjqi	104	5	5	5	CD
cord-017772-zpf1xjqi	104	6	is	be	VBZ
cord-017772-zpf1xjqi	104	7	compatible	compatible	JJ
cord-017772-zpf1xjqi	104	8	with	with	IN
cord-017772-zpf1xjqi	104	9	DIC	DIC	NNP
cord-017772-zpf1xjqi	104	10	,	,	,
cord-017772-zpf1xjqi	104	11	scoring	scoring	NN
cord-017772-zpf1xjqi	104	12	should	should	MD
cord-017772-zpf1xjqi	104	13	be	be	VB
cord-017772-zpf1xjqi	104	14	repeated	repeat	VBN
cord-017772-zpf1xjqi	104	15	daily	daily	RB
cord-017772-zpf1xjqi	104	16	.	.	.
cord-017772-zpf1xjqi	105	1	A	a	DT
cord-017772-zpf1xjqi	105	2	score	score	NN
cord-017772-zpf1xjqi	105	3	<	<	XX
cord-017772-zpf1xjqi	105	4	5	5	CD
cord-017772-zpf1xjqi	105	5	is	be	VBZ
cord-017772-zpf1xjqi	105	6	suggestive	suggestive	JJ
cord-017772-zpf1xjqi	105	7	of	of	IN
cord-017772-zpf1xjqi	105	8	non	non	JJ
cord-017772-zpf1xjqi	105	9	-	-	JJ
cord-017772-zpf1xjqi	105	10	overt	overt	JJ
cord-017772-zpf1xjqi	105	11	DIC	DIC	NNP
cord-017772-zpf1xjqi	105	12	,	,	,
cord-017772-zpf1xjqi	105	13	scoring	scoring	NN
cord-017772-zpf1xjqi	105	14	should	should	MD
cord-017772-zpf1xjqi	105	15	be	be	VB
cord-017772-zpf1xjqi	105	16	repeated	repeat	VBN
cord-017772-zpf1xjqi	105	17	in	in	IN
cord-017772-zpf1xjqi	105	18	the	the	DT
cord-017772-zpf1xjqi	105	19	next	next	JJ
cord-017772-zpf1xjqi	105	20	1	1	CD
cord-017772-zpf1xjqi	105	21	-	-	SYM
cord-017772-zpf1xjqi	105	22	2	2	CD
cord-017772-zpf1xjqi	105	23	days	day	NNS
cord-017772-zpf1xjqi	106	1	Data	datum	NNS
cord-017772-zpf1xjqi	106	2	adapted	adapt	VBN
cord-017772-zpf1xjqi	106	3	from	from	IN
cord-017772-zpf1xjqi	106	4	Mitta	Mitta	NNP
cord-017772-zpf1xjqi	106	5	[	[	-LRB-
cord-017772-zpf1xjqi	106	6	51	51	CD
cord-017772-zpf1xjqi	106	7	]	]	-RRB-
cord-017772-zpf1xjqi	106	8	,	,	,
cord-017772-zpf1xjqi	106	9	Reese	Reese	NNP
cord-017772-zpf1xjqi	106	10	[	[	-LRB-
cord-017772-zpf1xjqi	106	11	47	47	CD
cord-017772-zpf1xjqi	106	12	]	]	-RRB-
cord-017772-zpf1xjqi	106	13	,	,	,
cord-017772-zpf1xjqi	106	14	and	and	CC
cord-017772-zpf1xjqi	106	15	the	the	DT
cord-017772-zpf1xjqi	106	16	University	University	NNP
cord-017772-zpf1xjqi	106	17	of	of	IN
cord-017772-zpf1xjqi	106	18	Oklahoma	Oklahoma	NNP
cord-017772-zpf1xjqi	106	19	web	web	NN
cord-017772-zpf1xjqi	106	20	resource	resource	NN
cord-017772-zpf1xjqi	106	21	https://ouhsc.edu/platelets/ditp.html	https://ouhsc.edu/platelets/ditp.html	ADD
cord-017772-zpf1xjqi	106	22	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	106	23	and	and	CC
cord-017772-zpf1xjqi	106	24	drug	drug	NN
cord-017772-zpf1xjqi	106	25	-	-	HYPH
cord-017772-zpf1xjqi	106	26	induced	induce	VBN
cord-017772-zpf1xjqi	106	27	immune	immune	JJ
cord-017772-zpf1xjqi	106	28	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	106	29	[	[	-LRB-
cord-017772-zpf1xjqi	106	30	48	48	CD
cord-017772-zpf1xjqi	106	31	]	]	-RRB-
cord-017772-zpf1xjqi	106	32	.	.	.
cord-017772-zpf1xjqi	107	1	Drug	drug	NN
cord-017772-zpf1xjqi	107	2	-	-	HYPH
cord-017772-zpf1xjqi	107	3	induced	induce	VBN
cord-017772-zpf1xjqi	107	4	non	non	JJ
cord-017772-zpf1xjqi	107	5	-	-	JJ
cord-017772-zpf1xjqi	107	6	immune	immune	JJ
cord-017772-zpf1xjqi	107	7	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	107	8	is	be	VBZ
cord-017772-zpf1xjqi	107	9	far	far	RB
cord-017772-zpf1xjqi	107	10	more	more	RBR
cord-017772-zpf1xjqi	107	11	common	common	JJ
cord-017772-zpf1xjqi	107	12	and	and	CC
cord-017772-zpf1xjqi	107	13	is	be	VBZ
cord-017772-zpf1xjqi	107	14	characterized	characterize	VBN
cord-017772-zpf1xjqi	107	15	by	by	IN
cord-017772-zpf1xjqi	107	16	dose	dose	NN
cord-017772-zpf1xjqi	107	17	-	-	HYPH
cord-017772-zpf1xjqi	107	18	dependent	dependent	JJ
cord-017772-zpf1xjqi	107	19	suppression	suppression	NN
cord-017772-zpf1xjqi	107	20	of	of	IN
cord-017772-zpf1xjqi	107	21	bone	bone	NN
cord-017772-zpf1xjqi	107	22	marrow	marrow	NN
cord-017772-zpf1xjqi	107	23	platelet	platelet	NN
cord-017772-zpf1xjqi	107	24	production	production	NN
cord-017772-zpf1xjqi	107	25	.	.	.
cord-017772-zpf1xjqi	108	1	Representative	representative	JJ
cord-017772-zpf1xjqi	108	2	medications	medication	NNS
cord-017772-zpf1xjqi	108	3	include	include	VBP
cord-017772-zpf1xjqi	108	4	linezolid	linezolid	NNP
cord-017772-zpf1xjqi	108	5	,	,	,
cord-017772-zpf1xjqi	108	6	chemotherapeutics	chemotherapeutic	NNS
cord-017772-zpf1xjqi	108	7	,	,	,
cord-017772-zpf1xjqi	108	8	and	and	CC
cord-017772-zpf1xjqi	108	9	immunosuppressive	immunosuppressive	JJ
cord-017772-zpf1xjqi	108	10	agents	agent	NNS
cord-017772-zpf1xjqi	108	11	like	like	IN
cord-017772-zpf1xjqi	108	12	azathioprine	azathioprine	NN
cord-017772-zpf1xjqi	108	13	[	[	-LRB-
cord-017772-zpf1xjqi	108	14	49	49	CD
cord-017772-zpf1xjqi	108	15	]	]	-RRB-
cord-017772-zpf1xjqi	108	16	.	.	.
cord-017772-zpf1xjqi	109	1	Drug	drug	NN
cord-017772-zpf1xjqi	109	2	-	-	HYPH
cord-017772-zpf1xjqi	109	3	induced	induce	VBN
cord-017772-zpf1xjqi	109	4	immune	immune	JJ
cord-017772-zpf1xjqi	109	5	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	109	6	occurs	occur	VBZ
cord-017772-zpf1xjqi	109	7	through	through	IN
cord-017772-zpf1xjqi	109	8	a	a	DT
cord-017772-zpf1xjqi	109	9	variety	variety	NN
cord-017772-zpf1xjqi	109	10	of	of	IN
cord-017772-zpf1xjqi	109	11	mechanisms	mechanism	NNS
cord-017772-zpf1xjqi	109	12	.	.	.
cord-017772-zpf1xjqi	110	1	Rarely	rarely	RB
cord-017772-zpf1xjqi	110	2	,	,	,
cord-017772-zpf1xjqi	110	3	medications	medication	NNS
cord-017772-zpf1xjqi	110	4	may	may	MD
cord-017772-zpf1xjqi	110	5	induce	induce	VB
cord-017772-zpf1xjqi	110	6	autoantibodies	autoantibody	NNS
cord-017772-zpf1xjqi	110	7	that	that	WDT
cord-017772-zpf1xjqi	110	8	destroy	destroy	VBP
cord-017772-zpf1xjqi	110	9	host	host	NN
cord-017772-zpf1xjqi	110	10	platelets	platelet	NNS
cord-017772-zpf1xjqi	110	11	in	in	IN
cord-017772-zpf1xjqi	110	12	the	the	DT
cord-017772-zpf1xjqi	110	13	absence	absence	NN
cord-017772-zpf1xjqi	110	14	of	of	IN
cord-017772-zpf1xjqi	110	15	the	the	DT
cord-017772-zpf1xjqi	110	16	drug	drug	NN
cord-017772-zpf1xjqi	110	17	.	.	.
cord-017772-zpf1xjqi	111	1	Examples	example	NNS
cord-017772-zpf1xjqi	111	2	include	include	VBP
cord-017772-zpf1xjqi	111	3	gold	gold	NN
cord-017772-zpf1xjqi	111	4	salts	salt	NNS
cord-017772-zpf1xjqi	111	5	and	and	CC
cord-017772-zpf1xjqi	111	6	procainamide	procainamide	VB
cord-017772-zpf1xjqi	111	7	[	[	-LRB-
cord-017772-zpf1xjqi	111	8	50	50	CD
cord-017772-zpf1xjqi	111	9	]	]	-RRB-
cord-017772-zpf1xjqi	111	10	.	.	.
cord-017772-zpf1xjqi	112	1	More	more	RBR
cord-017772-zpf1xjqi	112	2	commonly	commonly	RB
cord-017772-zpf1xjqi	112	3	,	,	,
cord-017772-zpf1xjqi	112	4	a	a	DT
cord-017772-zpf1xjqi	112	5	drug	drug	NN
cord-017772-zpf1xjqi	112	6	will	will	MD
cord-017772-zpf1xjqi	112	7	induce	induce	VB
cord-017772-zpf1xjqi	112	8	the	the	DT
cord-017772-zpf1xjqi	112	9	production	production	NN
cord-017772-zpf1xjqi	112	10	of	of	IN
cord-017772-zpf1xjqi	112	11	antibodies	antibody	NNS
cord-017772-zpf1xjqi	112	12	that	that	WDT
cord-017772-zpf1xjqi	112	13	bind	bind	VBP
cord-017772-zpf1xjqi	112	14	to	to	IN
cord-017772-zpf1xjqi	112	15	an	an	DT
cord-017772-zpf1xjqi	112	16	epitope	epitope	NN
cord-017772-zpf1xjqi	112	17	on	on	IN
cord-017772-zpf1xjqi	112	18	a	a	DT
cord-017772-zpf1xjqi	112	19	platelet	platelet	NN
cord-017772-zpf1xjqi	112	20	glycoprotein	glycoprotein	NN
cord-017772-zpf1xjqi	112	21	in	in	IN
cord-017772-zpf1xjqi	112	22	the	the	DT
cord-017772-zpf1xjqi	112	23	presence	presence	NN
cord-017772-zpf1xjqi	112	24	of	of	IN
cord-017772-zpf1xjqi	112	25	the	the	DT
cord-017772-zpf1xjqi	112	26	medication	medication	NN
cord-017772-zpf1xjqi	112	27	.	.	.
cord-017772-zpf1xjqi	113	1	Many	many	JJ
cord-017772-zpf1xjqi	113	2	antibiotics	antibiotic	NNS
cord-017772-zpf1xjqi	113	3	including	include	VBG
cord-017772-zpf1xjqi	113	4	aztreonam	aztreonam	NNP
cord-017772-zpf1xjqi	113	5	,	,	,
cord-017772-zpf1xjqi	113	6	piperacillin	piperacillin	NNP
cord-017772-zpf1xjqi	113	7	,	,	,
cord-017772-zpf1xjqi	113	8	sulfonamides	sulfonamide	NNS
cord-017772-zpf1xjqi	113	9	,	,	,
cord-017772-zpf1xjqi	113	10	and	and	CC
cord-017772-zpf1xjqi	113	11	vancomycin	vancomycin	NN
cord-017772-zpf1xjqi	113	12	likely	likely	RB
cord-017772-zpf1xjqi	113	13	act	act	VBP
cord-017772-zpf1xjqi	113	14	through	through	IN
cord-017772-zpf1xjqi	113	15	this	this	DT
cord-017772-zpf1xjqi	113	16	mechanism	mechanism	NN
cord-017772-zpf1xjqi	113	17	[	[	-LRB-
cord-017772-zpf1xjqi	113	18	51	51	CD
cord-017772-zpf1xjqi	113	19	]	]	-RRB-
cord-017772-zpf1xjqi	113	20	.	.	.
cord-017772-zpf1xjqi	114	1	Heparin	heparin	NN
cord-017772-zpf1xjqi	114	2	-	-	HYPH
cord-017772-zpf1xjqi	114	3	induced	induce	VBN
cord-017772-zpf1xjqi	114	4	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	114	5	(	(	-LRB-
cord-017772-zpf1xjqi	114	6	HIT	hit	NN
cord-017772-zpf1xjqi	114	7	)	)	-RRB-
cord-017772-zpf1xjqi	114	8	is	be	VBZ
cord-017772-zpf1xjqi	114	9	a	a	DT
cord-017772-zpf1xjqi	114	10	particularly	particularly	RB
cord-017772-zpf1xjqi	114	11	important	important	JJ
cord-017772-zpf1xjqi	114	12	example	example	NN
cord-017772-zpf1xjqi	114	13	and	and	CC
cord-017772-zpf1xjqi	114	14	is	be	VBZ
cord-017772-zpf1xjqi	114	15	reviewed	review	VBN
cord-017772-zpf1xjqi	114	16	in	in	IN
cord-017772-zpf1xjqi	114	17	detail	detail	NN
cord-017772-zpf1xjqi	114	18	below	below	RB
cord-017772-zpf1xjqi	114	19	.	.	.
cord-017772-zpf1xjqi	115	1	Finally	finally	RB
cord-017772-zpf1xjqi	115	2	,	,	,
cord-017772-zpf1xjqi	115	3	antiplatelet	antiplatelet	NN
cord-017772-zpf1xjqi	115	4	agents	agent	NNS
cord-017772-zpf1xjqi	115	5	such	such	JJ
cord-017772-zpf1xjqi	115	6	as	as	IN
cord-017772-zpf1xjqi	115	7	eptifibatide	eptifibatide	NNP
cord-017772-zpf1xjqi	115	8	used	use	VBN
cord-017772-zpf1xjqi	115	9	in	in	IN
cord-017772-zpf1xjqi	115	10	the	the	DT
cord-017772-zpf1xjqi	115	11	treatment	treatment	NN
cord-017772-zpf1xjqi	115	12	of	of	IN
cord-017772-zpf1xjqi	115	13	acute	acute	JJ
cord-017772-zpf1xjqi	115	14	coronary	coronary	JJ
cord-017772-zpf1xjqi	115	15	syndrome	syndrome	NN
cord-017772-zpf1xjqi	115	16	facilitate	facilitate	VBP
cord-017772-zpf1xjqi	115	17	antibody	antibody	NN
cord-017772-zpf1xjqi	115	18	-	-	HYPH
cord-017772-zpf1xjqi	115	19	mediated	mediate	VBN
cord-017772-zpf1xjqi	115	20	destruction	destruction	NN
cord-017772-zpf1xjqi	115	21	of	of	IN
cord-017772-zpf1xjqi	115	22	platelets	platelet	NNS
cord-017772-zpf1xjqi	115	23	through	through	IN
cord-017772-zpf1xjqi	115	24	their	-PRON-	PRP$
cord-017772-zpf1xjqi	115	25	binding	binding	NN
cord-017772-zpf1xjqi	115	26	of	of	IN
cord-017772-zpf1xjqi	115	27	glycoprotein	glycoprotein	NN
cord-017772-zpf1xjqi	115	28	IIb	IIb	NNP
cord-017772-zpf1xjqi	115	29	/	/	SYM
cord-017772-zpf1xjqi	115	30	IIIa	iiia	NN
cord-017772-zpf1xjqi	115	31	[	[	-LRB-
cord-017772-zpf1xjqi	115	32	4	4	CD
cord-017772-zpf1xjqi	115	33	]	]	-RRB-
cord-017772-zpf1xjqi	115	34	.	.	.
cord-017772-zpf1xjqi	116	1	Drug	drug	NN
cord-017772-zpf1xjqi	116	2	-	-	HYPH
cord-017772-zpf1xjqi	116	3	induced	induce	VBN
cord-017772-zpf1xjqi	116	4	immune	immune	NN
cord-017772-zpf1xjqi	116	5	-	-	HYPH
cord-017772-zpf1xjqi	116	6	mediated	mediate	VBN
cord-017772-zpf1xjqi	116	7	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	116	8	typically	typically	RB
cord-017772-zpf1xjqi	116	9	occurs	occur	VBZ
cord-017772-zpf1xjqi	116	10	5	5	CD
cord-017772-zpf1xjqi	116	11	-	-	SYM
cord-017772-zpf1xjqi	116	12	7	7	CD
cord-017772-zpf1xjqi	116	13	days	day	NNS
cord-017772-zpf1xjqi	116	14	after	after	IN
cord-017772-zpf1xjqi	116	15	exposure	exposure	NN
cord-017772-zpf1xjqi	116	16	to	to	IN
cord-017772-zpf1xjqi	116	17	the	the	DT
cord-017772-zpf1xjqi	116	18	causative	causative	JJ
cord-017772-zpf1xjqi	116	19	medication	medication	NN
cord-017772-zpf1xjqi	116	20	.	.	.
cord-017772-zpf1xjqi	117	1	Thrombocytopenia	Thrombocytopenia	NNP
cord-017772-zpf1xjqi	117	2	is	be	VBZ
cord-017772-zpf1xjqi	117	3	often	often	RB
cord-017772-zpf1xjqi	117	4	severe	severe	JJ
cord-017772-zpf1xjqi	117	5	with	with	IN
cord-017772-zpf1xjqi	117	6	platelet	platelet	NN
cord-017772-zpf1xjqi	117	7	counts	count	NNS
cord-017772-zpf1xjqi	117	8	falling	fall	VBG
cord-017772-zpf1xjqi	117	9	to	to	IN
cord-017772-zpf1xjqi	117	10	<	<	XX
cord-017772-zpf1xjqi	117	11	20	20	CD
cord-017772-zpf1xjqi	117	12	x	x	SYM
cord-017772-zpf1xjqi	117	13	10	10	CD
cord-017772-zpf1xjqi	117	14	9	9	CD
cord-017772-zpf1xjqi	117	15	cells	cell	NNS
cord-017772-zpf1xjqi	117	16	/	/	SYM
cord-017772-zpf1xjqi	117	17	L.	L.	NNP
cord-017772-zpf1xjqi	117	18	Mucocutaneous	Mucocutaneous	NNP
cord-017772-zpf1xjqi	117	19	bleeding	bleed	VBG
cord-017772-zpf1xjqi	117	20	and	and	CC
cord-017772-zpf1xjqi	117	21	systemic	systemic	JJ
cord-017772-zpf1xjqi	117	22	symptoms	symptom	NNS
cord-017772-zpf1xjqi	117	23	may	may	MD
cord-017772-zpf1xjqi	117	24	be	be	VB
cord-017772-zpf1xjqi	117	25	present	present	JJ
cord-017772-zpf1xjqi	117	26	[	[	-LRB-
cord-017772-zpf1xjqi	117	27	48	48	CD
cord-017772-zpf1xjqi	117	28	]	]	-RRB-
cord-017772-zpf1xjqi	117	29	.	.	.
cord-017772-zpf1xjqi	118	1	The	the	DT
cord-017772-zpf1xjqi	118	2	diagnosis	diagnosis	NN
cord-017772-zpf1xjqi	118	3	requires	require	VBZ
cord-017772-zpf1xjqi	118	4	a	a	DT
cord-017772-zpf1xjqi	118	5	high	high	JJ
cord-017772-zpf1xjqi	118	6	index	index	NN
cord-017772-zpf1xjqi	118	7	of	of	IN
cord-017772-zpf1xjqi	118	8	suspicion	suspicion	NN
cord-017772-zpf1xjqi	118	9	given	give	VBN
cord-017772-zpf1xjqi	118	10	the	the	DT
cord-017772-zpf1xjqi	118	11	lag	lag	NN
cord-017772-zpf1xjqi	118	12	between	between	IN
cord-017772-zpf1xjqi	118	13	when	when	WRB
cord-017772-zpf1xjqi	118	14	a	a	DT
cord-017772-zpf1xjqi	118	15	drug	drug	NN
cord-017772-zpf1xjqi	118	16	is	be	VBZ
cord-017772-zpf1xjqi	118	17	started	start	VBN
cord-017772-zpf1xjqi	118	18	and	and	CC
cord-017772-zpf1xjqi	118	19	the	the	DT
cord-017772-zpf1xjqi	118	20	subsequent	subsequent	JJ
cord-017772-zpf1xjqi	118	21	fall	fall	NN
cord-017772-zpf1xjqi	118	22	in	in	IN
cord-017772-zpf1xjqi	118	23	platelet	platelet	NN
cord-017772-zpf1xjqi	118	24	count	count	NN
cord-017772-zpf1xjqi	118	25	.	.	.
cord-017772-zpf1xjqi	119	1	Identifying	identify	VBG
cord-017772-zpf1xjqi	119	2	drug	drug	NN
cord-017772-zpf1xjqi	119	3	-	-	HYPH
cord-017772-zpf1xjqi	119	4	dependent	dependent	JJ
cord-017772-zpf1xjqi	119	5	platelet	platelet	NN
cord-017772-zpf1xjqi	119	6	reactive	reactive	JJ
cord-017772-zpf1xjqi	119	7	antibodies	antibody	NNS
cord-017772-zpf1xjqi	119	8	helps	help	VBZ
cord-017772-zpf1xjqi	119	9	confirm	confirm	VB
cord-017772-zpf1xjqi	119	10	the	the	DT
cord-017772-zpf1xjqi	119	11	diagnosis	diagnosis	NN
cord-017772-zpf1xjqi	119	12	;	;	:
cord-017772-zpf1xjqi	119	13	however	however	RB
cord-017772-zpf1xjqi	119	14	,	,	,
cord-017772-zpf1xjqi	119	15	testing	testing	NN
cord-017772-zpf1xjqi	119	16	is	be	VBZ
cord-017772-zpf1xjqi	119	17	time	time	NN
cord-017772-zpf1xjqi	119	18	consuming	consume	VBG
cord-017772-zpf1xjqi	119	19	and	and	CC
cord-017772-zpf1xjqi	119	20	available	available	JJ
cord-017772-zpf1xjqi	119	21	at	at	IN
cord-017772-zpf1xjqi	119	22	a	a	DT
cord-017772-zpf1xjqi	119	23	limited	limited	JJ
cord-017772-zpf1xjqi	119	24	number	number	NN
cord-017772-zpf1xjqi	119	25	of	of	IN
cord-017772-zpf1xjqi	119	26	centers	center	NNS
cord-017772-zpf1xjqi	119	27	.	.	.
cord-017772-zpf1xjqi	120	1	Treatment	treatment	NN
cord-017772-zpf1xjqi	120	2	is	be	VBZ
cord-017772-zpf1xjqi	120	3	focused	focus	VBN
cord-017772-zpf1xjqi	120	4	on	on	IN
cord-017772-zpf1xjqi	120	5	the	the	DT
cord-017772-zpf1xjqi	120	6	identification	identification	NN
cord-017772-zpf1xjqi	120	7	and	and	CC
cord-017772-zpf1xjqi	120	8	removal	removal	NN
cord-017772-zpf1xjqi	120	9	of	of	IN
cord-017772-zpf1xjqi	120	10	the	the	DT
cord-017772-zpf1xjqi	120	11	causative	causative	JJ
cord-017772-zpf1xjqi	120	12	medication	medication	NN
cord-017772-zpf1xjqi	120	13	.	.	.
cord-017772-zpf1xjqi	121	1	When	when	WRB
cord-017772-zpf1xjqi	121	2	the	the	DT
cord-017772-zpf1xjqi	121	3	offending	offending	JJ
cord-017772-zpf1xjqi	121	4	drug	drug	NN
cord-017772-zpf1xjqi	121	5	is	be	VBZ
cord-017772-zpf1xjqi	121	6	removed	remove	VBN
cord-017772-zpf1xjqi	121	7	,	,	,
cord-017772-zpf1xjqi	121	8	platelets	platelet	NNS
cord-017772-zpf1xjqi	121	9	typically	typically	RB
cord-017772-zpf1xjqi	121	10	begin	begin	VBP
cord-017772-zpf1xjqi	121	11	to	to	TO
cord-017772-zpf1xjqi	121	12	improve	improve	VB
cord-017772-zpf1xjqi	121	13	in	in	IN
cord-017772-zpf1xjqi	121	14	1	1	CD
cord-017772-zpf1xjqi	121	15	-	-	SYM
cord-017772-zpf1xjqi	121	16	2	2	CD
cord-017772-zpf1xjqi	121	17	days	day	NNS
cord-017772-zpf1xjqi	121	18	.	.	.
cord-017772-zpf1xjqi	122	1	The	the	DT
cord-017772-zpf1xjqi	122	2	role	role	NN
cord-017772-zpf1xjqi	122	3	of	of	IN
cord-017772-zpf1xjqi	122	4	steroids	steroid	NNS
cord-017772-zpf1xjqi	122	5	and	and	CC
cord-017772-zpf1xjqi	122	6	intravenous	intravenous	JJ
cord-017772-zpf1xjqi	122	7	immunoglobulin	immunoglobulin	NN
cord-017772-zpf1xjqi	122	8	in	in	IN
cord-017772-zpf1xjqi	122	9	the	the	DT
cord-017772-zpf1xjqi	122	10	treatment	treatment	NN
cord-017772-zpf1xjqi	122	11	of	of	IN
cord-017772-zpf1xjqi	122	12	refractory	refractory	JJ
cord-017772-zpf1xjqi	122	13	drug	drug	NN
cord-017772-zpf1xjqi	122	14	-	-	HYPH
cord-017772-zpf1xjqi	122	15	induced	induce	VBN
cord-017772-zpf1xjqi	122	16	immune	immune	JJ
cord-017772-zpf1xjqi	122	17	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	122	18	is	be	VBZ
cord-017772-zpf1xjqi	122	19	controversial	controversial	JJ
cord-017772-zpf1xjqi	122	20	[	[	-LRB-
cord-017772-zpf1xjqi	122	21	50	50	CD
cord-017772-zpf1xjqi	122	22	]	]	-RRB-
cord-017772-zpf1xjqi	122	23	.	.	.
cord-017772-zpf1xjqi	123	1	A	a	DT
cord-017772-zpf1xjqi	123	2	helpful	helpful	JJ
cord-017772-zpf1xjqi	123	3	website	website	NN
cord-017772-zpf1xjqi	123	4	,	,	,
cord-017772-zpf1xjqi	123	5	https://ouhsc.edu/platelets/ditp.html	https://ouhsc.edu/platelets/ditp.html	ADD
cord-017772-zpf1xjqi	123	6	,	,	,
cord-017772-zpf1xjqi	123	7	includes	include	VBZ
cord-017772-zpf1xjqi	123	8	a	a	DT
cord-017772-zpf1xjqi	123	9	curated	curated	JJ
cord-017772-zpf1xjqi	123	10	list	list	NN
cord-017772-zpf1xjqi	123	11	of	of	IN
cord-017772-zpf1xjqi	123	12	all	all	DT
cord-017772-zpf1xjqi	123	13	drugs	drug	NNS
cord-017772-zpf1xjqi	123	14	associated	associate	VBN
cord-017772-zpf1xjqi	123	15	with	with	IN
cord-017772-zpf1xjqi	123	16	drugdependent	drugdependent	NN
cord-017772-zpf1xjqi	123	17	platelet	platelet	NN
cord-017772-zpf1xjqi	123	18	-	-	HYPH
cord-017772-zpf1xjqi	123	19	reactive	reactive	JJ
cord-017772-zpf1xjqi	123	20	antibodies	antibody	NNS
cord-017772-zpf1xjqi	123	21	identified	identify	VBN
cord-017772-zpf1xjqi	123	22	by	by	IN
cord-017772-zpf1xjqi	123	23	the	the	DT
cord-017772-zpf1xjqi	123	24	BloodCenter	BloodCenter	NNP
cord-017772-zpf1xjqi	123	25	of	of	IN
cord-017772-zpf1xjqi	123	26	Wisconsin	Wisconsin	NNP
cord-017772-zpf1xjqi	123	27	dating	date	VBG
cord-017772-zpf1xjqi	123	28	back	back	RB
cord-017772-zpf1xjqi	123	29	to	to	IN
cord-017772-zpf1xjqi	123	30	1995	1995	CD
cord-017772-zpf1xjqi	123	31	.	.	.
cord-017772-zpf1xjqi	124	1	HIT	HIT	NNP
cord-017772-zpf1xjqi	124	2	is	be	VBZ
cord-017772-zpf1xjqi	124	3	caused	cause	VBN
cord-017772-zpf1xjqi	124	4	by	by	IN
cord-017772-zpf1xjqi	124	5	the	the	DT
cord-017772-zpf1xjqi	124	6	production	production	NN
cord-017772-zpf1xjqi	124	7	of	of	IN
cord-017772-zpf1xjqi	124	8	host	host	NN
cord-017772-zpf1xjqi	124	9	IgG	IgG	NNP
cord-017772-zpf1xjqi	124	10	antibodies	antibody	NNS
cord-017772-zpf1xjqi	124	11	against	against	IN
cord-017772-zpf1xjqi	124	12	platelet	platelet	NN
cord-017772-zpf1xjqi	124	13	factor	factor	NN
cord-017772-zpf1xjqi	124	14	4	4	CD
cord-017772-zpf1xjqi	124	15	(	(	-LRB-
cord-017772-zpf1xjqi	124	16	PF4)-heparin	pf4)-heparin	NN
cord-017772-zpf1xjqi	124	17	complexes	complex	NNS
cord-017772-zpf1xjqi	124	18	.	.	.
cord-017772-zpf1xjqi	125	1	The	the	DT
cord-017772-zpf1xjqi	125	2	Fc	Fc	NNP
cord-017772-zpf1xjqi	125	3	domain	domain	NN
cord-017772-zpf1xjqi	125	4	of	of	IN
cord-017772-zpf1xjqi	125	5	these	these	DT
cord-017772-zpf1xjqi	125	6	immune	immune	JJ
cord-017772-zpf1xjqi	125	7	complexes	complex	NNS
cord-017772-zpf1xjqi	125	8	binds	bind	VBZ
cord-017772-zpf1xjqi	125	9	to	to	IN
cord-017772-zpf1xjqi	125	10	the	the	DT
cord-017772-zpf1xjqi	125	11	platelet	platelet	NN
cord-017772-zpf1xjqi	125	12	FCγ	fcγ	JJ
cord-017772-zpf1xjqi	125	13	RIIa	RIIa	NNS
cord-017772-zpf1xjqi	125	14	receptor	receptor	NN
cord-017772-zpf1xjqi	125	15	causing	cause	VBG
cord-017772-zpf1xjqi	125	16	platelet	platelet	NN
cord-017772-zpf1xjqi	125	17	aggregation	aggregation	NN
cord-017772-zpf1xjqi	125	18	,	,	,
cord-017772-zpf1xjqi	125	19	platelet	platelet	NN
cord-017772-zpf1xjqi	125	20	activation	activation	NN
cord-017772-zpf1xjqi	125	21	,	,	,
cord-017772-zpf1xjqi	125	22	and	and	CC
cord-017772-zpf1xjqi	125	23	eventual	eventual	JJ
cord-017772-zpf1xjqi	125	24	thrombin	thrombin	NN
cord-017772-zpf1xjqi	125	25	formation	formation	NN
cord-017772-zpf1xjqi	125	26	[	[	-LRB-
cord-017772-zpf1xjqi	125	27	52	52	CD
cord-017772-zpf1xjqi	125	28	]	]	-RRB-
cord-017772-zpf1xjqi	125	29	.	.	.
cord-017772-zpf1xjqi	126	1	Thrombocytopenia	Thrombocytopenia	NNP
cord-017772-zpf1xjqi	126	2	is	be	VBZ
cord-017772-zpf1xjqi	126	3	caused	cause	VBN
cord-017772-zpf1xjqi	126	4	by	by	IN
cord-017772-zpf1xjqi	126	5	intravascular	intravascular	JJ
cord-017772-zpf1xjqi	126	6	platelet	platelet	NN
cord-017772-zpf1xjqi	126	7	consumption	consumption	NN
cord-017772-zpf1xjqi	126	8	.	.	.
cord-017772-zpf1xjqi	127	1	While	while	IN
cord-017772-zpf1xjqi	127	2	a	a	DT
cord-017772-zpf1xjqi	127	3	diagnosis	diagnosis	NN
cord-017772-zpf1xjqi	127	4	of	of	IN
cord-017772-zpf1xjqi	127	5	HIT	HIT	NNP
cord-017772-zpf1xjqi	127	6	is	be	VBZ
cord-017772-zpf1xjqi	127	7	frequently	frequently	RB
cord-017772-zpf1xjqi	127	8	considered	consider	VBN
cord-017772-zpf1xjqi	127	9	for	for	IN
cord-017772-zpf1xjqi	127	10	thrombocytopenic	thrombocytopenic	JJ
cord-017772-zpf1xjqi	127	11	patients	patient	NNS
cord-017772-zpf1xjqi	127	12	in	in	IN
cord-017772-zpf1xjqi	127	13	the	the	DT
cord-017772-zpf1xjqi	127	14	ICU	ICU	NNP
cord-017772-zpf1xjqi	127	15	,	,	,
cord-017772-zpf1xjqi	127	16	it	-PRON-	PRP
cord-017772-zpf1xjqi	127	17	is	be	VBZ
cord-017772-zpf1xjqi	127	18	relatively	relatively	RB
cord-017772-zpf1xjqi	127	19	uncommon	uncommon	JJ
cord-017772-zpf1xjqi	127	20	.	.	.
cord-017772-zpf1xjqi	128	1	For	for	IN
cord-017772-zpf1xjqi	128	2	patients	patient	NNS
cord-017772-zpf1xjqi	128	3	in	in	IN
cord-017772-zpf1xjqi	128	4	the	the	DT
cord-017772-zpf1xjqi	128	5	medical	medical	JJ
cord-017772-zpf1xjqi	128	6	ICU	ICU	NNP
cord-017772-zpf1xjqi	128	7	,	,	,
cord-017772-zpf1xjqi	128	8	the	the	DT
cord-017772-zpf1xjqi	128	9	incidence	incidence	NN
cord-017772-zpf1xjqi	128	10	may	may	MD
cord-017772-zpf1xjqi	128	11	be	be	VB
cord-017772-zpf1xjqi	128	12	as	as	RB
cord-017772-zpf1xjqi	128	13	low	low	JJ
cord-017772-zpf1xjqi	128	14	as	as	IN
cord-017772-zpf1xjqi	128	15	0.02	0.02	CD
cord-017772-zpf1xjqi	128	16	%	%	NN
cord-017772-zpf1xjqi	128	17	[	[	-LRB-
cord-017772-zpf1xjqi	128	18	53	53	CD
cord-017772-zpf1xjqi	128	19	]	]	-RRB-
cord-017772-zpf1xjqi	128	20	.	.	.
cord-017772-zpf1xjqi	129	1	The	the	DT
cord-017772-zpf1xjqi	129	2	biggest	big	JJS
cord-017772-zpf1xjqi	129	3	risk	risk	NN
cord-017772-zpf1xjqi	129	4	factors	factor	NNS
cord-017772-zpf1xjqi	129	5	for	for	IN
cord-017772-zpf1xjqi	129	6	HIT	hit	NN
cord-017772-zpf1xjqi	129	7	include	include	VBP
cord-017772-zpf1xjqi	129	8	the	the	DT
cord-017772-zpf1xjqi	129	9	use	use	NN
cord-017772-zpf1xjqi	129	10	of	of	IN
cord-017772-zpf1xjqi	129	11	unfractionated	unfractionated	JJ
cord-017772-zpf1xjqi	129	12	heparin	heparin	NN
cord-017772-zpf1xjqi	129	13	and	and	CC
cord-017772-zpf1xjqi	129	14	cardiac	cardiac	JJ
cord-017772-zpf1xjqi	129	15	surgery	surgery	NN
cord-017772-zpf1xjqi	129	16	.	.	.
cord-017772-zpf1xjqi	130	1	In	in	IN
cord-017772-zpf1xjqi	130	2	these	these	DT
cord-017772-zpf1xjqi	130	3	settings	setting	NNS
cord-017772-zpf1xjqi	130	4	,	,	,
cord-017772-zpf1xjqi	130	5	the	the	DT
cord-017772-zpf1xjqi	130	6	incidence	incidence	NN
cord-017772-zpf1xjqi	130	7	increases	increase	VBZ
cord-017772-zpf1xjqi	130	8	up	up	IN
cord-017772-zpf1xjqi	130	9	to	to	TO
cord-017772-zpf1xjqi	130	10	3	3	CD
cord-017772-zpf1xjqi	130	11	%	%	NN
cord-017772-zpf1xjqi	130	12	[	[	-LRB-
cord-017772-zpf1xjqi	130	13	53	53	CD
cord-017772-zpf1xjqi	130	14	]	]	-RRB-
cord-017772-zpf1xjqi	130	15	.	.	.
cord-017772-zpf1xjqi	131	1	HIT	HIT	NNP
cord-017772-zpf1xjqi	131	2	is	be	VBZ
cord-017772-zpf1xjqi	131	3	unique	unique	JJ
cord-017772-zpf1xjqi	131	4	among	among	IN
cord-017772-zpf1xjqi	131	5	the	the	DT
cord-017772-zpf1xjqi	131	6	common	common	JJ
cord-017772-zpf1xjqi	131	7	causes	cause	NNS
cord-017772-zpf1xjqi	131	8	of	of	IN
cord-017772-zpf1xjqi	131	9	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	131	10	in	in	IN
cord-017772-zpf1xjqi	131	11	the	the	DT
cord-017772-zpf1xjqi	131	12	critically	critically	RB
cord-017772-zpf1xjqi	131	13	ill	ill	JJ
cord-017772-zpf1xjqi	131	14	in	in	IN
cord-017772-zpf1xjqi	131	15	that	that	IN
cord-017772-zpf1xjqi	131	16	it	-PRON-	PRP
cord-017772-zpf1xjqi	131	17	is	be	VBZ
cord-017772-zpf1xjqi	131	18	characterized	characterize	VBN
cord-017772-zpf1xjqi	131	19	by	by	IN
cord-017772-zpf1xjqi	131	20	thrombosis	thrombosis	NN
cord-017772-zpf1xjqi	131	21	rather	rather	RB
cord-017772-zpf1xjqi	131	22	than	than	IN
cord-017772-zpf1xjqi	131	23	bleeding	bleed	VBG
cord-017772-zpf1xjqi	131	24	.	.	.
cord-017772-zpf1xjqi	132	1	Over	over	IN
cord-017772-zpf1xjqi	132	2	50	50	CD
cord-017772-zpf1xjqi	132	3	%	%	NN
cord-017772-zpf1xjqi	132	4	of	of	IN
cord-017772-zpf1xjqi	132	5	patients	patient	NNS
cord-017772-zpf1xjqi	132	6	with	with	IN
cord-017772-zpf1xjqi	132	7	HIT	hit	NN
cord-017772-zpf1xjqi	132	8	develop	develop	VBP
cord-017772-zpf1xjqi	132	9	thrombosis	thrombosis	NN
cord-017772-zpf1xjqi	132	10	,	,	,
cord-017772-zpf1xjqi	132	11	most	most	RBS
cord-017772-zpf1xjqi	132	12	commonly	commonly	RB
cord-017772-zpf1xjqi	132	13	in	in	IN
cord-017772-zpf1xjqi	132	14	the	the	DT
cord-017772-zpf1xjqi	132	15	deep	deep	JJ
cord-017772-zpf1xjqi	132	16	veins	vein	NNS
cord-017772-zpf1xjqi	132	17	of	of	IN
cord-017772-zpf1xjqi	132	18	the	the	DT
cord-017772-zpf1xjqi	132	19	extremities	extremity	NNS
cord-017772-zpf1xjqi	132	20	and	and	CC
cord-017772-zpf1xjqi	132	21	pulmonary	pulmonary	JJ
cord-017772-zpf1xjqi	132	22	arteries	artery	NNS
cord-017772-zpf1xjqi	132	23	[	[	-LRB-
cord-017772-zpf1xjqi	132	24	53	53	CD
cord-017772-zpf1xjqi	132	25	,	,	,
cord-017772-zpf1xjqi	132	26	54	54	CD
cord-017772-zpf1xjqi	132	27	]	]	-RRB-
cord-017772-zpf1xjqi	132	28	.	.	.
cord-017772-zpf1xjqi	133	1	HIT	hit	VB
cord-017772-zpf1xjqi	133	2	can	can	MD
cord-017772-zpf1xjqi	133	3	also	also	RB
cord-017772-zpf1xjqi	133	4	cause	cause	VB
cord-017772-zpf1xjqi	133	5	arterial	arterial	JJ
cord-017772-zpf1xjqi	133	6	thrombosis	thrombosis	NN
cord-017772-zpf1xjqi	133	7	,	,	,
cord-017772-zpf1xjqi	133	8	thrombosis	thrombosis	NN
cord-017772-zpf1xjqi	133	9	in	in	IN
cord-017772-zpf1xjqi	133	10	unusual	unusual	JJ
cord-017772-zpf1xjqi	133	11	venous	venous	JJ
cord-017772-zpf1xjqi	133	12	structures	structure	NNS
cord-017772-zpf1xjqi	133	13	(	(	-LRB-
cord-017772-zpf1xjqi	133	14	e.g.	e.g.	IN
cord-017772-zpf1xjqi	133	15	mesenteric	mesenteric	JJ
cord-017772-zpf1xjqi	133	16	vessels	vessel	NNS
cord-017772-zpf1xjqi	133	17	)	)	-RRB-
cord-017772-zpf1xjqi	133	18	,	,	,
cord-017772-zpf1xjqi	133	19	and	and	CC
cord-017772-zpf1xjqi	133	20	myocardial	myocardial	JJ
cord-017772-zpf1xjqi	133	21	infarction	infarction	NN
cord-017772-zpf1xjqi	133	22	[	[	-LRB-
cord-017772-zpf1xjqi	133	23	54	54	CD
cord-017772-zpf1xjqi	133	24	]	]	-RRB-
cord-017772-zpf1xjqi	133	25	.	.	.
cord-017772-zpf1xjqi	134	1	HIT	hit	VB
cord-017772-zpf1xjqi	134	2	should	should	MD
cord-017772-zpf1xjqi	134	3	be	be	VB
cord-017772-zpf1xjqi	134	4	suspected	suspect	VBN
cord-017772-zpf1xjqi	134	5	when	when	WRB
cord-017772-zpf1xjqi	134	6	platelet	platelet	NN
cord-017772-zpf1xjqi	134	7	counts	count	NNS
cord-017772-zpf1xjqi	134	8	fall	fall	VBP
cord-017772-zpf1xjqi	134	9	by	by	IN
cord-017772-zpf1xjqi	134	10	at	at	RB
cord-017772-zpf1xjqi	134	11	least	least	RBS
cord-017772-zpf1xjqi	134	12	50	50	CD
cord-017772-zpf1xjqi	134	13	%	%	NN
cord-017772-zpf1xjqi	134	14	5	5	CD
cord-017772-zpf1xjqi	134	15	-	-	SYM
cord-017772-zpf1xjqi	134	16	10	10	CD
cord-017772-zpf1xjqi	134	17	days	day	NNS
cord-017772-zpf1xjqi	134	18	after	after	IN
cord-017772-zpf1xjqi	134	19	the	the	DT
cord-017772-zpf1xjqi	134	20	initiation	initiation	NN
cord-017772-zpf1xjqi	134	21	of	of	IN
cord-017772-zpf1xjqi	134	22	heparin	heparin	NN
cord-017772-zpf1xjqi	134	23	therapy	therapy	NN
cord-017772-zpf1xjqi	134	24	[	[	-LRB-
cord-017772-zpf1xjqi	134	25	55	55	CD
cord-017772-zpf1xjqi	134	26	]	]	-RRB-
cord-017772-zpf1xjqi	134	27	.	.	.
cord-017772-zpf1xjqi	135	1	An	an	DT
cord-017772-zpf1xjqi	135	2	important	important	JJ
cord-017772-zpf1xjqi	135	3	caveat	caveat	NN
cord-017772-zpf1xjqi	135	4	to	to	IN
cord-017772-zpf1xjqi	135	5	this	this	DT
cord-017772-zpf1xjqi	135	6	pattern	pattern	NN
cord-017772-zpf1xjqi	135	7	is	be	VBZ
cord-017772-zpf1xjqi	135	8	patients	patient	NNS
cord-017772-zpf1xjqi	135	9	who	who	WP
cord-017772-zpf1xjqi	135	10	have	have	VBP
cord-017772-zpf1xjqi	135	11	been	be	VBN
cord-017772-zpf1xjqi	135	12	previously	previously	RB
cord-017772-zpf1xjqi	135	13	exposed	expose	VBN
cord-017772-zpf1xjqi	135	14	to	to	IN
cord-017772-zpf1xjqi	135	15	heparin	heparin	NN
cord-017772-zpf1xjqi	135	16	.	.	.
cord-017772-zpf1xjqi	136	1	Host	host	NN
cord-017772-zpf1xjqi	136	2	IgG	igg	NN
cord-017772-zpf1xjqi	136	3	against	against	IN
cord-017772-zpf1xjqi	136	4	PF4heparin	PF4heparin	NNP
cord-017772-zpf1xjqi	136	5	complexes	complex	NNS
cord-017772-zpf1xjqi	136	6	can	can	MD
cord-017772-zpf1xjqi	136	7	remain	remain	VB
cord-017772-zpf1xjqi	136	8	active	active	JJ
cord-017772-zpf1xjqi	136	9	for	for	IN
cord-017772-zpf1xjqi	136	10	up	up	IN
cord-017772-zpf1xjqi	136	11	to	to	TO
cord-017772-zpf1xjqi	136	12	85	85	CD
cord-017772-zpf1xjqi	136	13	days	day	NNS
cord-017772-zpf1xjqi	136	14	.	.	.
cord-017772-zpf1xjqi	137	1	During	during	IN
cord-017772-zpf1xjqi	137	2	this	this	DT
cord-017772-zpf1xjqi	137	3	window	window	NN
cord-017772-zpf1xjqi	137	4	,	,	,
cord-017772-zpf1xjqi	137	5	heparin	heparin	NN
cord-017772-zpf1xjqi	137	6	re	re	NN
cord-017772-zpf1xjqi	137	7	-	-	NN
cord-017772-zpf1xjqi	137	8	exposure	exposure	NN
cord-017772-zpf1xjqi	137	9	can	can	MD
cord-017772-zpf1xjqi	137	10	produce	produce	VB
cord-017772-zpf1xjqi	137	11	a	a	DT
cord-017772-zpf1xjqi	137	12	rapid	rapid	JJ
cord-017772-zpf1xjqi	137	13	drop	drop	NN
cord-017772-zpf1xjqi	137	14	in	in	IN
cord-017772-zpf1xjqi	137	15	platelet	platelet	NN
cord-017772-zpf1xjqi	137	16	count	count	NN
cord-017772-zpf1xjqi	137	17	within	within	IN
cord-017772-zpf1xjqi	137	18	24	24	CD
cord-017772-zpf1xjqi	137	19	hours	hour	NNS
cord-017772-zpf1xjqi	137	20	[	[	-LRB-
cord-017772-zpf1xjqi	137	21	52	52	CD
cord-017772-zpf1xjqi	137	22	]	]	-RRB-
cord-017772-zpf1xjqi	137	23	.	.	.
cord-017772-zpf1xjqi	138	1	Up	up	IN
cord-017772-zpf1xjqi	138	2	to	to	TO
cord-017772-zpf1xjqi	138	3	30	30	CD
cord-017772-zpf1xjqi	138	4	%	%	NN
cord-017772-zpf1xjqi	138	5	of	of	IN
cord-017772-zpf1xjqi	138	6	cases	case	NNS
cord-017772-zpf1xjqi	138	7	of	of	IN
cord-017772-zpf1xjqi	138	8	HIT	HIT	NNP
cord-017772-zpf1xjqi	138	9	may	may	MD
cord-017772-zpf1xjqi	138	10	present	present	VB
cord-017772-zpf1xjqi	138	11	in	in	IN
cord-017772-zpf1xjqi	138	12	this	this	DT
cord-017772-zpf1xjqi	138	13	manner	manner	NN
cord-017772-zpf1xjqi	138	14	[	[	-LRB-
cord-017772-zpf1xjqi	138	15	55	55	CD
cord-017772-zpf1xjqi	138	16	]	]	-RRB-
cord-017772-zpf1xjqi	138	17	.	.	.
cord-017772-zpf1xjqi	139	1	Thrombocytopenia	Thrombocytopenia	NNP
cord-017772-zpf1xjqi	139	2	in	in	IN
cord-017772-zpf1xjqi	139	3	HIT	hit	NN
cord-017772-zpf1xjqi	139	4	is	be	VBZ
cord-017772-zpf1xjqi	139	5	generally	generally	RB
cord-017772-zpf1xjqi	139	6	less	less	RBR
cord-017772-zpf1xjqi	139	7	severe	severe	JJ
cord-017772-zpf1xjqi	139	8	than	than	IN
cord-017772-zpf1xjqi	139	9	other	other	JJ
cord-017772-zpf1xjqi	139	10	causes	cause	NNS
cord-017772-zpf1xjqi	139	11	of	of	IN
cord-017772-zpf1xjqi	139	12	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	139	13	in	in	IN
cord-017772-zpf1xjqi	139	14	the	the	DT
cord-017772-zpf1xjqi	139	15	ICU	ICU	NNP
cord-017772-zpf1xjqi	139	16	with	with	IN
cord-017772-zpf1xjqi	139	17	levels	level	NNS
cord-017772-zpf1xjqi	139	18	rarely	rarely	RB
cord-017772-zpf1xjqi	139	19	falling	fall	VBG
cord-017772-zpf1xjqi	139	20	below	below	IN
cord-017772-zpf1xjqi	139	21	20	20	CD
cord-017772-zpf1xjqi	139	22	×	×	NN
cord-017772-zpf1xjqi	139	23	10	10	CD
cord-017772-zpf1xjqi	139	24	9	9	CD
cord-017772-zpf1xjqi	139	25	cells	cell	NNS
cord-017772-zpf1xjqi	139	26	/	/	SYM
cord-017772-zpf1xjqi	139	27	L.	L.	NNP
cord-017772-zpf1xjqi	140	1	[	[	-LRB-
cord-017772-zpf1xjqi	140	2	54	54	CD
cord-017772-zpf1xjqi	140	3	]	]	-RRB-
cord-017772-zpf1xjqi	140	4	Up	up	IN
cord-017772-zpf1xjqi	140	5	to	to	TO
cord-017772-zpf1xjqi	140	6	20	20	CD
cord-017772-zpf1xjqi	140	7	%	%	NN
cord-017772-zpf1xjqi	140	8	of	of	IN
cord-017772-zpf1xjqi	140	9	patients	patient	NNS
cord-017772-zpf1xjqi	140	10	exposed	expose	VBN
cord-017772-zpf1xjqi	140	11	to	to	IN
cord-017772-zpf1xjqi	140	12	heparin	heparin	NN
cord-017772-zpf1xjqi	140	13	produce	produce	NN
cord-017772-zpf1xjqi	140	14	IgG	igg	NN
cord-017772-zpf1xjqi	140	15	antibodies	antibody	NNS
cord-017772-zpf1xjqi	140	16	against	against	IN
cord-017772-zpf1xjqi	140	17	PF4-heparin	pf4-heparin	NN
cord-017772-zpf1xjqi	140	18	complexes	complex	NNS
cord-017772-zpf1xjqi	140	19	while	while	IN
cord-017772-zpf1xjqi	140	20	only	only	RB
cord-017772-zpf1xjqi	140	21	a	a	DT
cord-017772-zpf1xjqi	140	22	small	small	JJ
cord-017772-zpf1xjqi	140	23	minority	minority	NN
cord-017772-zpf1xjqi	140	24	develop	develop	VB
cord-017772-zpf1xjqi	140	25	HIT	HIT	VBN
cord-017772-zpf1xjqi	140	26	[	[	-LRB-
cord-017772-zpf1xjqi	140	27	56	56	CD
cord-017772-zpf1xjqi	140	28	]	]	-RRB-
cord-017772-zpf1xjqi	140	29	.	.	.
cord-017772-zpf1xjqi	141	1	Given	give	VBN
cord-017772-zpf1xjqi	141	2	the	the	DT
cord-017772-zpf1xjqi	141	3	costs	cost	NNS
cord-017772-zpf1xjqi	141	4	associated	associate	VBN
cord-017772-zpf1xjqi	141	5	with	with	IN
cord-017772-zpf1xjqi	141	6	laboratory	laboratory	NN
cord-017772-zpf1xjqi	141	7	testing	testing	NN
cord-017772-zpf1xjqi	141	8	for	for	IN
cord-017772-zpf1xjqi	141	9	HIT	hit	NN
cord-017772-zpf1xjqi	141	10	and	and	CC
cord-017772-zpf1xjqi	141	11	the	the	DT
cord-017772-zpf1xjqi	141	12	potential	potential	JJ
cord-017772-zpf1xjqi	141	13	risk	risk	NN
cord-017772-zpf1xjqi	141	14	of	of	IN
cord-017772-zpf1xjqi	141	15	transitioning	transition	VBG
cord-017772-zpf1xjqi	141	16	to	to	IN
cord-017772-zpf1xjqi	141	17	a	a	DT
cord-017772-zpf1xjqi	141	18	non	non	JJ
cord-017772-zpf1xjqi	141	19	-	-	JJ
cord-017772-zpf1xjqi	141	20	heparin	heparin	JJ
cord-017772-zpf1xjqi	141	21	anticoagulant	anticoagulant	JJ
cord-017772-zpf1xjqi	141	22	agent	agent	NN
cord-017772-zpf1xjqi	141	23	,	,	,
cord-017772-zpf1xjqi	141	24	the	the	DT
cord-017772-zpf1xjqi	141	25	diagnosis	diagnosis	NN
cord-017772-zpf1xjqi	141	26	of	of	IN
cord-017772-zpf1xjqi	141	27	HIT	HIT	NNP
cord-017772-zpf1xjqi	141	28	should	should	MD
cord-017772-zpf1xjqi	141	29	only	only	RB
cord-017772-zpf1xjqi	141	30	be	be	VB
cord-017772-zpf1xjqi	141	31	pursued	pursue	VBN
cord-017772-zpf1xjqi	141	32	in	in	IN
cord-017772-zpf1xjqi	141	33	patients	patient	NNS
cord-017772-zpf1xjqi	141	34	with	with	IN
cord-017772-zpf1xjqi	141	35	an	an	DT
cord-017772-zpf1xjqi	141	36	intermediate	intermediate	JJ
cord-017772-zpf1xjqi	141	37	to	to	TO
cord-017772-zpf1xjqi	141	38	high	high	JJ
cord-017772-zpf1xjqi	141	39	pre	pre	JJ
cord-017772-zpf1xjqi	141	40	-	-	JJ
cord-017772-zpf1xjqi	141	41	test	test	JJ
cord-017772-zpf1xjqi	141	42	probability	probability	NN
cord-017772-zpf1xjqi	141	43	of	of	IN
cord-017772-zpf1xjqi	141	44	having	have	VBG
cord-017772-zpf1xjqi	141	45	the	the	DT
cord-017772-zpf1xjqi	141	46	disease	disease	NN
cord-017772-zpf1xjqi	141	47	[	[	-LRB-
cord-017772-zpf1xjqi	141	48	57	57	CD
cord-017772-zpf1xjqi	141	49	]	]	-RRB-
cord-017772-zpf1xjqi	141	50	.	.	.
cord-017772-zpf1xjqi	142	1	The	the	DT
cord-017772-zpf1xjqi	142	2	most	most	RBS
cord-017772-zpf1xjqi	142	3	widely	widely	RB
cord-017772-zpf1xjqi	142	4	used	use	VBN
cord-017772-zpf1xjqi	142	5	pre	pre	JJ
cord-017772-zpf1xjqi	142	6	-	-	JJ
cord-017772-zpf1xjqi	142	7	test	test	JJ
cord-017772-zpf1xjqi	142	8	probability	probability	NN
cord-017772-zpf1xjqi	142	9	assessment	assessment	NN
cord-017772-zpf1xjqi	142	10	tool	tool	NN
cord-017772-zpf1xjqi	142	11	for	for	IN
cord-017772-zpf1xjqi	142	12	HIT	HIT	NNP
cord-017772-zpf1xjqi	142	13	is	be	VBZ
cord-017772-zpf1xjqi	142	14	the	the	DT
cord-017772-zpf1xjqi	142	15	4Ts	4ts	JJ
cord-017772-zpf1xjqi	142	16	score	score	NN
cord-017772-zpf1xjqi	142	17	(	(	-LRB-
cord-017772-zpf1xjqi	142	18	Table	Table	NNP
cord-017772-zpf1xjqi	142	19	83	83	CD
cord-017772-zpf1xjqi	142	20	.	.	.
cord-017772-zpf1xjqi	142	21	3	3	LS
cord-017772-zpf1xjqi	142	22	)	)	-RRB-
cord-017772-zpf1xjqi	142	23	[	[	-LRB-
cord-017772-zpf1xjqi	142	24	58	58	CD
cord-017772-zpf1xjqi	142	25	]	]	-RRB-
cord-017772-zpf1xjqi	142	26	.	.	.
cord-017772-zpf1xjqi	143	1	A	a	DT
cord-017772-zpf1xjqi	143	2	score	score	NN
cord-017772-zpf1xjqi	143	3	<	<	XX
cord-017772-zpf1xjqi	143	4	4	4	CD
cord-017772-zpf1xjqi	143	5	is	be	VBZ
cord-017772-zpf1xjqi	143	6	associated	associate	VBN
cord-017772-zpf1xjqi	143	7	with	with	IN
cord-017772-zpf1xjqi	143	8	a	a	DT
cord-017772-zpf1xjqi	143	9	negative	negative	JJ
cord-017772-zpf1xjqi	143	10	predictive	predictive	JJ
cord-017772-zpf1xjqi	143	11	value	value	NN
cord-017772-zpf1xjqi	143	12	for	for	IN
cord-017772-zpf1xjqi	143	13	HIT	hit	NN
cord-017772-zpf1xjqi	143	14	of	of	IN
cord-017772-zpf1xjqi	143	15	>	>	$
cord-017772-zpf1xjqi	143	16	99	99	CD
cord-017772-zpf1xjqi	143	17	%	%	NN
cord-017772-zpf1xjqi	143	18	and	and	CC
cord-017772-zpf1xjqi	143	19	obviates	obviate	VBZ
cord-017772-zpf1xjqi	143	20	the	the	DT
cord-017772-zpf1xjqi	143	21	need	need	NN
cord-017772-zpf1xjqi	143	22	for	for	IN
cord-017772-zpf1xjqi	143	23	further	further	JJ
cord-017772-zpf1xjqi	143	24	testing	testing	NN
cord-017772-zpf1xjqi	143	25	[	[	-LRB-
cord-017772-zpf1xjqi	143	26	59	59	CD
cord-017772-zpf1xjqi	143	27	]	]	-RRB-
cord-017772-zpf1xjqi	143	28	.	.	.
cord-017772-zpf1xjqi	144	1	Patients	patient	NNS
cord-017772-zpf1xjqi	144	2	with	with	IN
cord-017772-zpf1xjqi	144	3	a	a	DT
cord-017772-zpf1xjqi	144	4	score	score	NN
cord-017772-zpf1xjqi	144	5	≥	≥	CD
cord-017772-zpf1xjqi	144	6	4	4	CD
cord-017772-zpf1xjqi	144	7	should	should	MD
cord-017772-zpf1xjqi	144	8	undergo	undergo	VB
cord-017772-zpf1xjqi	144	9	step	step	NN
cord-017772-zpf1xjqi	144	10	-	-	HYPH
cord-017772-zpf1xjqi	144	11	wise	wise	JJ
cord-017772-zpf1xjqi	144	12	serologic	serologic	NN
cord-017772-zpf1xjqi	144	13	testing	testing	NN
cord-017772-zpf1xjqi	144	14	.	.	.
cord-017772-zpf1xjqi	145	1	The	the	DT
cord-017772-zpf1xjqi	145	2	initial	initial	JJ
cord-017772-zpf1xjqi	145	3	serologic	serologic	JJ
cord-017772-zpf1xjqi	145	4	test	test	NN
cord-017772-zpf1xjqi	145	5	for	for	IN
cord-017772-zpf1xjqi	145	6	patients	patient	NNS
cord-017772-zpf1xjqi	145	7	with	with	IN
cord-017772-zpf1xjqi	145	8	an	an	DT
cord-017772-zpf1xjqi	145	9	intermediate	intermediate	JJ
cord-017772-zpf1xjqi	145	10	to	to	TO
cord-017772-zpf1xjqi	145	11	high	high	JJ
cord-017772-zpf1xjqi	145	12	pre	pre	JJ
cord-017772-zpf1xjqi	145	13	-	-	JJ
cord-017772-zpf1xjqi	145	14	test	test	JJ
cord-017772-zpf1xjqi	145	15	probability	probability	NN
cord-017772-zpf1xjqi	145	16	of	of	IN
cord-017772-zpf1xjqi	145	17	HIT	hit	NN
cord-017772-zpf1xjqi	145	18	is	be	VBZ
cord-017772-zpf1xjqi	145	19	an	an	DT
cord-017772-zpf1xjqi	145	20	enzyme	enzyme	NN
cord-017772-zpf1xjqi	145	21	-	-	HYPH
cord-017772-zpf1xjqi	145	22	linked	link	VBN
cord-017772-zpf1xjqi	145	23	immunoassay	immunoassay	NN
cord-017772-zpf1xjqi	145	24	(	(	-LRB-
cord-017772-zpf1xjqi	145	25	ELISA	ELISA	NNP
cord-017772-zpf1xjqi	145	26	)	)	-RRB-
cord-017772-zpf1xjqi	145	27	to	to	TO
cord-017772-zpf1xjqi	145	28	detect	detect	VB
cord-017772-zpf1xjqi	145	29	HIT	HIT	VBN
cord-017772-zpf1xjqi	145	30	antibodies	antibody	NNS
cord-017772-zpf1xjqi	145	31	.	.	.
cord-017772-zpf1xjqi	146	1	These	these	DT
cord-017772-zpf1xjqi	146	2	assays	assay	NNS
cord-017772-zpf1xjqi	146	3	are	be	VBP
cord-017772-zpf1xjqi	146	4	widely	widely	RB
cord-017772-zpf1xjqi	146	5	available	available	JJ
cord-017772-zpf1xjqi	146	6	and	and	CC
cord-017772-zpf1xjqi	146	7	result	result	VB
cord-017772-zpf1xjqi	146	8	in	in	IN
cord-017772-zpf1xjqi	146	9	a	a	DT
cord-017772-zpf1xjqi	146	10	matter	matter	NN
cord-017772-zpf1xjqi	146	11	of	of	IN
cord-017772-zpf1xjqi	146	12	hours	hour	NNS
cord-017772-zpf1xjqi	146	13	.	.	.
cord-017772-zpf1xjqi	147	1	IgG	igg	NN
cord-017772-zpf1xjqi	147	2	-	-	HYPH
cord-017772-zpf1xjqi	147	3	specific	specific	JJ
cord-017772-zpf1xjqi	147	4	ELISAs	elisa	NNS
cord-017772-zpf1xjqi	147	5	have	have	VBP
cord-017772-zpf1xjqi	147	6	a	a	DT
cord-017772-zpf1xjqi	147	7	sensitivity	sensitivity	NN
cord-017772-zpf1xjqi	147	8	of	of	IN
cord-017772-zpf1xjqi	147	9	96	96	CD
cord-017772-zpf1xjqi	147	10	%	%	NN
cord-017772-zpf1xjqi	147	11	and	and	CC
cord-017772-zpf1xjqi	147	12	specificity	specificity	NN
cord-017772-zpf1xjqi	147	13	of	of	IN
cord-017772-zpf1xjqi	147	14	89	89	CD
cord-017772-zpf1xjqi	147	15	%	%	NN
cord-017772-zpf1xjqi	147	16	for	for	IN
cord-017772-zpf1xjqi	147	17	the	the	DT
cord-017772-zpf1xjqi	147	18	diagnosis	diagnosis	NN
cord-017772-zpf1xjqi	147	19	of	of	IN
cord-017772-zpf1xjqi	147	20	HIT	hit	VB
cord-017772-zpf1xjqi	147	21	[	[	-LRB-
cord-017772-zpf1xjqi	147	22	60	60	CD
cord-017772-zpf1xjqi	147	23	]	]	-RRB-
cord-017772-zpf1xjqi	147	24	.	.	.
cord-017772-zpf1xjqi	148	1	Results	result	NNS
cord-017772-zpf1xjqi	148	2	are	be	VBP
cord-017772-zpf1xjqi	148	3	typically	typically	RB
cord-017772-zpf1xjqi	148	4	reported	report	VBN
cord-017772-zpf1xjqi	148	5	quantitatively	quantitatively	RB
cord-017772-zpf1xjqi	148	6	as	as	IN
cord-017772-zpf1xjqi	148	7	an	an	DT
cord-017772-zpf1xjqi	148	8	optical	optical	JJ
cord-017772-zpf1xjqi	148	9	density	density	NN
cord-017772-zpf1xjqi	148	10	(	(	-LRB-
cord-017772-zpf1xjqi	148	11	OD	OD	NNP
cord-017772-zpf1xjqi	148	12	)	)	-RRB-
cord-017772-zpf1xjqi	148	13	.	.	.
cord-017772-zpf1xjqi	149	1	The	the	DT
cord-017772-zpf1xjqi	149	2	higher	high	JJR
cord-017772-zpf1xjqi	149	3	the	the	DT
cord-017772-zpf1xjqi	149	4	OD	OD	NNP
cord-017772-zpf1xjqi	149	5	threshold	threshold	NN
cord-017772-zpf1xjqi	149	6	used	use	VBN
cord-017772-zpf1xjqi	149	7	to	to	TO
cord-017772-zpf1xjqi	149	8	identify	identify	VB
cord-017772-zpf1xjqi	149	9	a	a	DT
cord-017772-zpf1xjqi	149	10	positive	positive	JJ
cord-017772-zpf1xjqi	149	11	test	test	NN
cord-017772-zpf1xjqi	149	12	,	,	,
cord-017772-zpf1xjqi	149	13	the	the	DT
cord-017772-zpf1xjqi	149	14	more	more	RBR
cord-017772-zpf1xjqi	149	15	likely	likely	RB
cord-017772-zpf1xjqi	149	16	a	a	DT
cord-017772-zpf1xjqi	149	17	positive	positive	JJ
cord-017772-zpf1xjqi	149	18	ELISA	ELISA	NNP
cord-017772-zpf1xjqi	149	19	will	will	MD
cord-017772-zpf1xjqi	149	20	predict	predict	VB
cord-017772-zpf1xjqi	149	21	a	a	DT
cord-017772-zpf1xjqi	149	22	positive	positive	JJ
cord-017772-zpf1xjqi	149	23	functional	functional	JJ
cord-017772-zpf1xjqi	149	24	assay	assay	NN
cord-017772-zpf1xjqi	149	25	.	.	.
cord-017772-zpf1xjqi	150	1	The	the	DT
cord-017772-zpf1xjqi	150	2	commonly	commonly	RB
cord-017772-zpf1xjqi	150	3	used	use	VBN
cord-017772-zpf1xjqi	150	4	OD	OD	NNP
cord-017772-zpf1xjqi	150	5	cutoff	cutoff	NN
cord-017772-zpf1xjqi	150	6	of	of	IN
cord-017772-zpf1xjqi	150	7	0.4	0.4	CD
cord-017772-zpf1xjqi	150	8	has	have	VBZ
cord-017772-zpf1xjqi	150	9	a	a	DT
cord-017772-zpf1xjqi	150	10	sensitivity	sensitivity	NN
cord-017772-zpf1xjqi	150	11	of	of	IN
cord-017772-zpf1xjqi	150	12	>	>	$
cord-017772-zpf1xjqi	150	13	99	99	CD
cord-017772-zpf1xjqi	150	14	%	%	NN
cord-017772-zpf1xjqi	150	15	for	for	IN
cord-017772-zpf1xjqi	150	16	HIT	hit	NN
cord-017772-zpf1xjqi	150	17	[	[	-LRB-
cord-017772-zpf1xjqi	150	18	53	53	CD
cord-017772-zpf1xjqi	150	19	]	]	-RRB-
cord-017772-zpf1xjqi	150	20	.	.	.
cord-017772-zpf1xjqi	151	1	Patients	patient	NNS
cord-017772-zpf1xjqi	151	2	with	with	IN
cord-017772-zpf1xjqi	151	3	a	a	DT
cord-017772-zpf1xjqi	151	4	positive	positive	JJ
cord-017772-zpf1xjqi	151	5	ELISA	ELISA	NNP
cord-017772-zpf1xjqi	151	6	should	should	MD
cord-017772-zpf1xjqi	151	7	undergo	undergo	VB
cord-017772-zpf1xjqi	151	8	confirmatory	confirmatory	JJ
cord-017772-zpf1xjqi	151	9	testing	testing	NN
cord-017772-zpf1xjqi	151	10	with	with	IN
cord-017772-zpf1xjqi	151	11	a	a	DT
cord-017772-zpf1xjqi	151	12	functional	functional	JJ
cord-017772-zpf1xjqi	151	13	assay	assay	NN
cord-017772-zpf1xjqi	151	14	-typically	-typically	WDT
cord-017772-zpf1xjqi	151	15	a	a	DT
cord-017772-zpf1xjqi	151	16	serotonin	serotonin	NN
cord-017772-zpf1xjqi	151	17	release	release	NN
cord-017772-zpf1xjqi	151	18	assay	assay	NN
cord-017772-zpf1xjqi	151	19	(	(	-LRB-
cord-017772-zpf1xjqi	151	20	SRA	SRA	NNP
cord-017772-zpf1xjqi	151	21	)	)	-RRB-
cord-017772-zpf1xjqi	151	22	.	.	.
cord-017772-zpf1xjqi	152	1	A	a	DT
cord-017772-zpf1xjqi	152	2	SRA	SRA	NNP
cord-017772-zpf1xjqi	152	3	evaluates	evaluate	VBZ
cord-017772-zpf1xjqi	152	4	for	for	IN
cord-017772-zpf1xjqi	152	5	in	in	FW
cord-017772-zpf1xjqi	152	6	vitro	vitro	FW
cord-017772-zpf1xjqi	152	7	activation	activation	NN
cord-017772-zpf1xjqi	152	8	of	of	IN
cord-017772-zpf1xjqi	152	9	platelets	platelet	NNS
cord-017772-zpf1xjqi	152	10	in	in	IN
cord-017772-zpf1xjqi	152	11	the	the	DT
cord-017772-zpf1xjqi	152	12	presence	presence	NN
cord-017772-zpf1xjqi	152	13	of	of	IN
cord-017772-zpf1xjqi	152	14	patient	patient	JJ
cord-017772-zpf1xjqi	152	15	serum	serum	NN
cord-017772-zpf1xjqi	152	16	and	and	CC
cord-017772-zpf1xjqi	152	17	heparin	heparin	NN
cord-017772-zpf1xjqi	152	18	.	.	.
cord-017772-zpf1xjqi	153	1	A	a	DT
cord-017772-zpf1xjqi	153	2	positive	positive	JJ
cord-017772-zpf1xjqi	153	3	SRA	SRA	NNP
cord-017772-zpf1xjqi	153	4	has	have	VBZ
cord-017772-zpf1xjqi	153	5	a	a	DT
cord-017772-zpf1xjqi	153	6	specificity	specificity	NN
cord-017772-zpf1xjqi	153	7	of	of	IN
cord-017772-zpf1xjqi	153	8	nearly	nearly	RB
cord-017772-zpf1xjqi	153	9	100	100	CD
cord-017772-zpf1xjqi	153	10	%	%	NN
cord-017772-zpf1xjqi	153	11	for	for	IN
cord-017772-zpf1xjqi	153	12	the	the	DT
cord-017772-zpf1xjqi	153	13	diagnosis	diagnosis	NN
cord-017772-zpf1xjqi	153	14	of	of	IN
cord-017772-zpf1xjqi	153	15	HIT	hit	VB
cord-017772-zpf1xjqi	153	16	[	[	-LRB-
cord-017772-zpf1xjqi	153	17	60	60	CD
cord-017772-zpf1xjqi	153	18	]	]	-RRB-
cord-017772-zpf1xjqi	153	19	.	.	.
cord-017772-zpf1xjqi	154	1	The	the	DT
cord-017772-zpf1xjqi	154	2	cornerstone	cornerstone	NN
cord-017772-zpf1xjqi	154	3	of	of	IN
cord-017772-zpf1xjqi	154	4	management	management	NN
cord-017772-zpf1xjqi	154	5	for	for	IN
cord-017772-zpf1xjqi	154	6	patients	patient	NNS
cord-017772-zpf1xjqi	154	7	with	with	IN
cord-017772-zpf1xjqi	154	8	either	either	CC
cord-017772-zpf1xjqi	154	9	an	an	DT
cord-017772-zpf1xjqi	154	10	intermediate	intermediate	JJ
cord-017772-zpf1xjqi	154	11	to	to	TO
cord-017772-zpf1xjqi	154	12	high	high	JJ
cord-017772-zpf1xjqi	154	13	pre	pre	JJ
cord-017772-zpf1xjqi	154	14	-	-	JJ
cord-017772-zpf1xjqi	154	15	test	test	JJ
cord-017772-zpf1xjqi	154	16	probability	probability	NN
cord-017772-zpf1xjqi	154	17	of	of	IN
cord-017772-zpf1xjqi	154	18	HIT	hit	NN
cord-017772-zpf1xjqi	154	19	or	or	CC
cord-017772-zpf1xjqi	154	20	a	a	DT
cord-017772-zpf1xjqi	154	21	confirmed	confirm	VBN
cord-017772-zpf1xjqi	154	22	diagnosis	diagnosis	NN
cord-017772-zpf1xjqi	154	23	is	be	VBZ
cord-017772-zpf1xjqi	154	24	transition	transition	NN
cord-017772-zpf1xjqi	154	25	to	to	IN
cord-017772-zpf1xjqi	154	26	a	a	DT
cord-017772-zpf1xjqi	154	27	non	non	JJ
cord-017772-zpf1xjqi	154	28	-	-	JJ
cord-017772-zpf1xjqi	154	29	heparin	heparin	JJ
cord-017772-zpf1xjqi	154	30	anticoagulant	anticoagulant	NN
cord-017772-zpf1xjqi	154	31	.	.	.
cord-017772-zpf1xjqi	155	1	Options	option	NNS
cord-017772-zpf1xjqi	155	2	include	include	VBP
cord-017772-zpf1xjqi	155	3	direct	direct	JJ
cord-017772-zpf1xjqi	155	4	thrombin	thrombin	NN
cord-017772-zpf1xjqi	155	5	inhibitors	inhibitor	NNS
cord-017772-zpf1xjqi	155	6	(	(	-LRB-
cord-017772-zpf1xjqi	155	7	e.g.	e.g.	RB
cord-017772-zpf1xjqi	155	8	,	,	,
cord-017772-zpf1xjqi	155	9	lepirudin	lepirudin	NNS
cord-017772-zpf1xjqi	155	10	,	,	,
cord-017772-zpf1xjqi	155	11	argatroban	argatroban	NNP
cord-017772-zpf1xjqi	155	12	,	,	,
cord-017772-zpf1xjqi	155	13	and	and	CC
cord-017772-zpf1xjqi	155	14	bivalrudin	bivalrudin	NNP
cord-017772-zpf1xjqi	155	15	)	)	-RRB-
cord-017772-zpf1xjqi	155	16	and	and	CC
cord-017772-zpf1xjqi	155	17	factor	factor	NN
cord-017772-zpf1xjqi	155	18	Xa	Xa	NNP
cord-017772-zpf1xjqi	155	19	inhibitors	inhibitor	NNS
cord-017772-zpf1xjqi	155	20	(	(	-LRB-
cord-017772-zpf1xjqi	155	21	e.g.	e.g.	RB
cord-017772-zpf1xjqi	155	22	,	,	,
cord-017772-zpf1xjqi	155	23	danaparoid	danaparoid	NN
cord-017772-zpf1xjqi	155	24	and	and	CC
cord-017772-zpf1xjqi	155	25	fondaparinux	fondaparinux	NNP
cord-017772-zpf1xjqi	155	26	)	)	-RRB-
cord-017772-zpf1xjqi	155	27	[	[	-LRB-
cord-017772-zpf1xjqi	155	28	54	54	CD
cord-017772-zpf1xjqi	155	29	]	]	-RRB-
cord-017772-zpf1xjqi	155	30	.	.	.
cord-017772-zpf1xjqi	156	1	There	there	EX
cord-017772-zpf1xjqi	156	2	is	be	VBZ
cord-017772-zpf1xjqi	156	3	currently	currently	RB
cord-017772-zpf1xjqi	156	4	insufficient	insufficient	JJ
cord-017772-zpf1xjqi	156	5	evidence	evidence	NN
cord-017772-zpf1xjqi	156	6	to	to	TO
cord-017772-zpf1xjqi	156	7	support	support	VB
cord-017772-zpf1xjqi	156	8	the	the	DT
cord-017772-zpf1xjqi	156	9	use	use	NN
cord-017772-zpf1xjqi	156	10	of	of	IN
cord-017772-zpf1xjqi	156	11	direct	direct	JJ
cord-017772-zpf1xjqi	156	12	oral	oral	JJ
cord-017772-zpf1xjqi	156	13	anticoagulant	anticoagulant	JJ
cord-017772-zpf1xjqi	156	14	agents	agent	NNS
cord-017772-zpf1xjqi	156	15	in	in	IN
cord-017772-zpf1xjqi	156	16	this	this	DT
cord-017772-zpf1xjqi	156	17	setting	set	VBG
cord-017772-zpf1xjqi	156	18	[	[	-LRB-
cord-017772-zpf1xjqi	156	19	53	53	CD
cord-017772-zpf1xjqi	156	20	]	]	-RRB-
cord-017772-zpf1xjqi	156	21	.	.	.
cord-017772-zpf1xjqi	157	1	Warfarin	Warfarin	NNP
cord-017772-zpf1xjqi	157	2	is	be	VBZ
cord-017772-zpf1xjqi	157	3	contraindicated	contraindicated	JJ
cord-017772-zpf1xjqi	157	4	in	in	IN
cord-017772-zpf1xjqi	157	5	patients	patient	NNS
cord-017772-zpf1xjqi	157	6	with	with	IN
cord-017772-zpf1xjqi	157	7	HIT	hit	NN
cord-017772-zpf1xjqi	157	8	until	until	IN
cord-017772-zpf1xjqi	157	9	the	the	DT
cord-017772-zpf1xjqi	157	10	platelet	platelet	NN
cord-017772-zpf1xjqi	157	11	counts	count	VBZ
cord-017772-zpf1xjqi	157	12	rises	rise	VBZ
cord-017772-zpf1xjqi	157	13	above	above	IN
cord-017772-zpf1xjqi	157	14	150	150	CD
cord-017772-zpf1xjqi	157	15	x	x	SYM
cord-017772-zpf1xjqi	157	16	10	10	CD
cord-017772-zpf1xjqi	157	17	9	9	CD
cord-017772-zpf1xjqi	157	18	cells	cell	NNS
cord-017772-zpf1xjqi	157	19	/	/	SYM
cord-017772-zpf1xjqi	157	20	L	l	NN
cord-017772-zpf1xjqi	157	21	as	as	IN
cord-017772-zpf1xjqi	157	22	warfarin	warfarin	NN
cord-017772-zpf1xjqi	157	23	reduces	reduce	VBZ
cord-017772-zpf1xjqi	157	24	protein	protein	NN
cord-017772-zpf1xjqi	157	25	C	c	NN
cord-017772-zpf1xjqi	157	26	levels	level	NNS
cord-017772-zpf1xjqi	157	27	and	and	CC
cord-017772-zpf1xjqi	157	28	may	may	MD
cord-017772-zpf1xjqi	157	29	exacerbate	exacerbate	VB
cord-017772-zpf1xjqi	157	30	thrombus	thrombus	NN
cord-017772-zpf1xjqi	157	31	formation	formation	NN
cord-017772-zpf1xjqi	157	32	[	[	-LRB-
cord-017772-zpf1xjqi	157	33	54	54	CD
cord-017772-zpf1xjqi	157	34	]	]	-RRB-
cord-017772-zpf1xjqi	157	35	.	.	.
cord-017772-zpf1xjqi	158	1	Platelet	platelet	NN
cord-017772-zpf1xjqi	158	2	transfusions	transfusion	NNS
cord-017772-zpf1xjqi	158	3	should	should	MD
cord-017772-zpf1xjqi	158	4	be	be	VB
cord-017772-zpf1xjqi	158	5	avoided	avoid	VBN
cord-017772-zpf1xjqi	158	6	if	if	IN
cord-017772-zpf1xjqi	158	7	possible	possible	JJ
cord-017772-zpf1xjqi	158	8	and	and	CC
cord-017772-zpf1xjqi	158	9	are	be	VBP
cord-017772-zpf1xjqi	158	10	only	only	RB
cord-017772-zpf1xjqi	158	11	recommended	recommend	VBN
cord-017772-zpf1xjqi	158	12	for	for	IN
cord-017772-zpf1xjqi	158	13	patients	patient	NNS
cord-017772-zpf1xjqi	158	14	who	who	WP
cord-017772-zpf1xjqi	158	15	are	be	VBP
cord-017772-zpf1xjqi	158	16	actively	actively	RB
cord-017772-zpf1xjqi	158	17	bleeding	bleed	VBG
cord-017772-zpf1xjqi	158	18	or	or	CC
cord-017772-zpf1xjqi	158	19	those	those	DT
cord-017772-zpf1xjqi	158	20	undergoing	undergo	VBG
cord-017772-zpf1xjqi	158	21	an	an	DT
cord-017772-zpf1xjqi	158	22	invasive	invasive	JJ
cord-017772-zpf1xjqi	158	23	procedure	procedure	NN
cord-017772-zpf1xjqi	158	24	associated	associate	VBN
cord-017772-zpf1xjqi	158	25	with	with	IN
cord-017772-zpf1xjqi	158	26	a	a	DT
cord-017772-zpf1xjqi	158	27	high	high	JJ
cord-017772-zpf1xjqi	158	28	risk	risk	NN
cord-017772-zpf1xjqi	158	29	of	of	IN
cord-017772-zpf1xjqi	158	30	bleeding	bleed	VBG
cord-017772-zpf1xjqi	158	31	[	[	-LRB-
cord-017772-zpf1xjqi	158	32	54	54	CD
cord-017772-zpf1xjqi	158	33	]	]	-RRB-
cord-017772-zpf1xjqi	158	34	.	.	.
cord-017772-zpf1xjqi	159	1	Sepsis	sepsis	NN
cord-017772-zpf1xjqi	159	2	is	be	VBZ
cord-017772-zpf1xjqi	159	3	one	one	CD
cord-017772-zpf1xjqi	159	4	of	of	IN
cord-017772-zpf1xjqi	159	5	the	the	DT
cord-017772-zpf1xjqi	159	6	most	most	RBS
cord-017772-zpf1xjqi	159	7	common	common	JJ
cord-017772-zpf1xjqi	159	8	causes	cause	NNS
cord-017772-zpf1xjqi	159	9	of	of	IN
cord-017772-zpf1xjqi	159	10	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	159	11	in	in	IN
cord-017772-zpf1xjqi	159	12	the	the	DT
cord-017772-zpf1xjqi	159	13	ICU	ICU	NNP
cord-017772-zpf1xjqi	159	14	and	and	CC
cord-017772-zpf1xjqi	159	15	may	may	MD
cord-017772-zpf1xjqi	159	16	contribute	contribute	VB
cord-017772-zpf1xjqi	159	17	to	to	IN
cord-017772-zpf1xjqi	159	18	a	a	DT
cord-017772-zpf1xjqi	159	19	low	low	JJ
cord-017772-zpf1xjqi	159	20	platelet	platelet	NN
cord-017772-zpf1xjqi	159	21	count	count	NN
cord-017772-zpf1xjqi	159	22	in	in	IN
cord-017772-zpf1xjqi	159	23	up	up	IN
cord-017772-zpf1xjqi	159	24	to	to	TO
cord-017772-zpf1xjqi	159	25	75	75	CD
cord-017772-zpf1xjqi	159	26	%	%	NN
cord-017772-zpf1xjqi	159	27	of	of	IN
cord-017772-zpf1xjqi	159	28	casas	casa	NNS
cord-017772-zpf1xjqi	159	29	[	[	-LRB-
cord-017772-zpf1xjqi	159	30	17	17	CD
cord-017772-zpf1xjqi	159	31	]	]	-RRB-
cord-017772-zpf1xjqi	159	32	.	.	.
cord-017772-zpf1xjqi	160	1	The	the	DT
cord-017772-zpf1xjqi	160	2	incidence	incidence	NN
cord-017772-zpf1xjqi	160	3	of	of	IN
cord-017772-zpf1xjqi	160	4	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	160	5	in	in	IN
cord-017772-zpf1xjqi	160	6	patients	patient	NNS
cord-017772-zpf1xjqi	160	7	with	with	IN
cord-017772-zpf1xjqi	160	8	sepsis	sepsis	NN
cord-017772-zpf1xjqi	160	9	varies	vary	VBZ
cord-017772-zpf1xjqi	160	10	by	by	IN
cord-017772-zpf1xjqi	160	11	illness	illness	NN
cord-017772-zpf1xjqi	160	12	severity	severity	NN
cord-017772-zpf1xjqi	160	13	.	.	.
cord-017772-zpf1xjqi	161	1	In	in	IN
cord-017772-zpf1xjqi	161	2	a	a	DT
cord-017772-zpf1xjqi	161	3	multicenter	multicenter	JJ
cord-017772-zpf1xjqi	161	4	prospective	prospective	JJ
cord-017772-zpf1xjqi	161	5	evaluation	evaluation	NN
cord-017772-zpf1xjqi	161	6	of	of	IN
cord-017772-zpf1xjqi	161	7	1238	1238	CD
cord-017772-zpf1xjqi	161	8	patients	patient	NNS
cord-017772-zpf1xjqi	161	9	with	with	IN
cord-017772-zpf1xjqi	161	10	severe	severe	JJ
cord-017772-zpf1xjqi	161	11	sepsis	sepsis	NN
cord-017772-zpf1xjqi	161	12	,	,	,
cord-017772-zpf1xjqi	161	13	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	161	14	was	be	VBD
cord-017772-zpf1xjqi	161	15	present	present	JJ
cord-017772-zpf1xjqi	161	16	in	in	IN
cord-017772-zpf1xjqi	161	17	14.5	14.5	CD
cord-017772-zpf1xjqi	161	18	%	%	NN
cord-017772-zpf1xjqi	161	19	of	of	IN
cord-017772-zpf1xjqi	161	20	patients	patient	NNS
cord-017772-zpf1xjqi	161	21	[	[	-LRB-
cord-017772-zpf1xjqi	161	22	61	61	CD
cord-017772-zpf1xjqi	161	23	]	]	-RRB-
cord-017772-zpf1xjqi	161	24	.	.	.
cord-017772-zpf1xjqi	162	1	In	in	IN
cord-017772-zpf1xjqi	162	2	patients	patient	NNS
cord-017772-zpf1xjqi	162	3	with	with	IN
cord-017772-zpf1xjqi	162	4	septic	septic	JJ
cord-017772-zpf1xjqi	162	5	shock	shock	NN
cord-017772-zpf1xjqi	162	6	,	,	,
cord-017772-zpf1xjqi	162	7	the	the	DT
cord-017772-zpf1xjqi	162	8	incidence	incidence	NN
cord-017772-zpf1xjqi	162	9	of	of	IN
cord-017772-zpf1xjqi	162	10	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	162	11	approaches	approach	VBZ
cord-017772-zpf1xjqi	162	12	50	50	CD
cord-017772-zpf1xjqi	162	13	%	%	NN
cord-017772-zpf1xjqi	162	14	[	[	-LRB-
cord-017772-zpf1xjqi	162	15	62	62	CD
cord-017772-zpf1xjqi	162	16	,	,	,
cord-017772-zpf1xjqi	162	17	63	63	CD
cord-017772-zpf1xjqi	162	18	]	]	-RRB-
cord-017772-zpf1xjqi	162	19	.	.	.
cord-017772-zpf1xjqi	163	1	Thrombocytopenia	Thrombocytopenia	NNP
cord-017772-zpf1xjqi	163	2	has	have	VBZ
cord-017772-zpf1xjqi	163	3	consistently	consistently	RB
cord-017772-zpf1xjqi	163	4	been	be	VBN
cord-017772-zpf1xjqi	163	5	associated	associate	VBN
cord-017772-zpf1xjqi	163	6	with	with	IN
cord-017772-zpf1xjqi	163	7	increased	increase	VBN
cord-017772-zpf1xjqi	163	8	mortality	mortality	NN
cord-017772-zpf1xjqi	163	9	in	in	IN
cord-017772-zpf1xjqi	163	10	septic	septic	JJ
cord-017772-zpf1xjqi	163	11	patients	patient	NNS
cord-017772-zpf1xjqi	163	12	[	[	-LRB-
cord-017772-zpf1xjqi	163	13	10	10	CD
cord-017772-zpf1xjqi	163	14	,	,	,
cord-017772-zpf1xjqi	163	15	61	61	CD
cord-017772-zpf1xjqi	163	16	,	,	,
cord-017772-zpf1xjqi	163	17	62	62	CD
cord-017772-zpf1xjqi	163	18	]	]	-RRB-
cord-017772-zpf1xjqi	163	19	.	.	.
cord-017772-zpf1xjqi	164	1	Multiple	multiple	JJ
cord-017772-zpf1xjqi	164	2	mechanisms	mechanism	NNS
cord-017772-zpf1xjqi	164	3	cause	cause	VBP
cord-017772-zpf1xjqi	164	4	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	164	5	during	during	IN
cord-017772-zpf1xjqi	164	6	sepsis	sepsis	NN
cord-017772-zpf1xjqi	164	7	.	.	.
cord-017772-zpf1xjqi	165	1	Decreased	decrease	VBN
cord-017772-zpf1xjqi	165	2	bone	bone	NN
cord-017772-zpf1xjqi	165	3	marrow	marrow	NN
cord-017772-zpf1xjqi	165	4	production	production	NN
cord-017772-zpf1xjqi	165	5	,	,	,
cord-017772-zpf1xjqi	165	6	hemophagocytosis	hemophagocytosis	NN
cord-017772-zpf1xjqi	165	7	,	,	,
cord-017772-zpf1xjqi	165	8	platelet	platelet	NN
cord-017772-zpf1xjqi	165	9	consumption	consumption	NN
cord-017772-zpf1xjqi	165	10	in	in	IN
cord-017772-zpf1xjqi	165	11	microvascular	microvascular	JJ
cord-017772-zpf1xjqi	165	12	beds	bed	NNS
cord-017772-zpf1xjqi	165	13	,	,	,
cord-017772-zpf1xjqi	165	14	sequestration	sequestration	NN
cord-017772-zpf1xjqi	165	15	,	,	,
cord-017772-zpf1xjqi	165	16	and	and	CC
cord-017772-zpf1xjqi	165	17	hemodilution	hemodilution	NN
cord-017772-zpf1xjqi	165	18	may	may	MD
cord-017772-zpf1xjqi	165	19	all	all	RB
cord-017772-zpf1xjqi	165	20	contribute	contribute	VB
cord-017772-zpf1xjqi	165	21	to	to	IN
cord-017772-zpf1xjqi	165	22	varying	vary	VBG
cord-017772-zpf1xjqi	165	23	degrees	degree	NNS
cord-017772-zpf1xjqi	165	24	[	[	-LRB-
cord-017772-zpf1xjqi	165	25	64	64	CD
cord-017772-zpf1xjqi	165	26	]	]	-RRB-
cord-017772-zpf1xjqi	165	27	.	.	.
cord-017772-zpf1xjqi	166	1	Septic	septic	JJ
cord-017772-zpf1xjqi	166	2	patients	patient	NNS
cord-017772-zpf1xjqi	166	3	are	be	VBP
cord-017772-zpf1xjqi	166	4	at	at	IN
cord-017772-zpf1xjqi	166	5	high	high	JJ
cord-017772-zpf1xjqi	166	6	risk	risk	NN
cord-017772-zpf1xjqi	166	7	for	for	IN
cord-017772-zpf1xjqi	166	8	DIC	DIC	NNP
cord-017772-zpf1xjqi	166	9	which	which	WDT
cord-017772-zpf1xjqi	166	10	can	can	MD
cord-017772-zpf1xjqi	166	11	further	further	RB
cord-017772-zpf1xjqi	166	12	lower	low	JJR
cord-017772-zpf1xjqi	166	13	platelet	platelet	NN
cord-017772-zpf1xjqi	166	14	counts	count	NNS
cord-017772-zpf1xjqi	166	15	.	.	.
cord-017772-zpf1xjqi	167	1	Additionally	additionally	RB
cord-017772-zpf1xjqi	167	2	,	,	,
cord-017772-zpf1xjqi	167	3	many	many	JJ
cord-017772-zpf1xjqi	167	4	medications	medication	NNS
cord-017772-zpf1xjqi	167	5	routinely	routinely	RB
cord-017772-zpf1xjqi	167	6	administered	administer	VBN
cord-017772-zpf1xjqi	167	7	to	to	TO
cord-017772-zpf1xjqi	167	8	septic	septic	JJ
cord-017772-zpf1xjqi	167	9	patients	patient	NNS
cord-017772-zpf1xjqi	167	10	including	include	VBG
cord-017772-zpf1xjqi	167	11	antibiotics	antibiotic	NNS
cord-017772-zpf1xjqi	167	12	are	be	VBP
cord-017772-zpf1xjqi	167	13	associated	associate	VBN
cord-017772-zpf1xjqi	167	14	with	with	IN
cord-017772-zpf1xjqi	167	15	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	167	16	.	.	.
cord-017772-zpf1xjqi	168	1	Based	base	VBN
cord-017772-zpf1xjqi	168	2	on	on	IN
cord-017772-zpf1xjqi	168	3	very	very	RB
cord-017772-zpf1xjqi	168	4	low	low	JJ
cord-017772-zpf1xjqi	168	5	-	-	HYPH
cord-017772-zpf1xjqi	168	6	quality	quality	NN
cord-017772-zpf1xjqi	168	7	evidence	evidence	NN
cord-017772-zpf1xjqi	168	8	,	,	,
cord-017772-zpf1xjqi	168	9	the	the	DT
cord-017772-zpf1xjqi	168	10	Surviving	Surviving	NNP
cord-017772-zpf1xjqi	168	11	Sepsis	Sepsis	NNP
cord-017772-zpf1xjqi	168	12	Campaign	Campaign	NNP
cord-017772-zpf1xjqi	168	13	recommends	recommend	VBZ
cord-017772-zpf1xjqi	168	14	prophylactic	prophylactic	JJ
cord-017772-zpf1xjqi	168	15	platelet	platelet	NN
cord-017772-zpf1xjqi	168	16	transfusions	transfusion	NNS
cord-017772-zpf1xjqi	168	17	in	in	IN
cord-017772-zpf1xjqi	168	18	septic	septic	JJ
cord-017772-zpf1xjqi	168	19	patients	patient	NNS
cord-017772-zpf1xjqi	168	20	with	with	IN
cord-017772-zpf1xjqi	168	21	a	a	DT
cord-017772-zpf1xjqi	168	22	platelet	platelet	NN
cord-017772-zpf1xjqi	168	23	count	count	NN
cord-017772-zpf1xjqi	168	24	<	<	XX
cord-017772-zpf1xjqi	168	25	10	10	CD
cord-017772-zpf1xjqi	168	26	×	×	NN
cord-017772-zpf1xjqi	168	27	10	10	CD
cord-017772-zpf1xjqi	168	28	9	9	CD
cord-017772-zpf1xjqi	168	29	cells	cell	NNS
cord-017772-zpf1xjqi	168	30	/	/	SYM
cord-017772-zpf1xjqi	168	31	L	l	NN
cord-017772-zpf1xjqi	168	32	and	and	CC
cord-017772-zpf1xjqi	168	33	20	20	CD
cord-017772-zpf1xjqi	168	34	×	×	NN
cord-017772-zpf1xjqi	168	35	10	10	CD
cord-017772-zpf1xjqi	168	36	9	9	CD
cord-017772-zpf1xjqi	168	37	cells	cell	NNS
cord-017772-zpf1xjqi	168	38	/	/	SYM
cord-017772-zpf1xjqi	168	39	L	l	NN
cord-017772-zpf1xjqi	168	40	for	for	IN
cord-017772-zpf1xjqi	168	41	patients	patient	NNS
cord-017772-zpf1xjqi	168	42	at	at	IN
cord-017772-zpf1xjqi	168	43	high	high	JJ
cord-017772-zpf1xjqi	168	44	risk	risk	NN
cord-017772-zpf1xjqi	168	45	of	of	IN
cord-017772-zpf1xjqi	168	46	bleeding	bleed	VBG
cord-017772-zpf1xjqi	168	47	.	.	.
cord-017772-zpf1xjqi	169	1	A	a	DT
cord-017772-zpf1xjqi	169	2	platelet	platelet	NN
cord-017772-zpf1xjqi	169	3	count	count	NN
cord-017772-zpf1xjqi	169	4	>	>	XX
cord-017772-zpf1xjqi	170	1	50	50	CD
cord-017772-zpf1xjqi	170	2	×	×	NN
cord-017772-zpf1xjqi	170	3	10	10	CD
cord-017772-zpf1xjqi	170	4	9	9	CD
cord-017772-zpf1xjqi	170	5	cells/	cells/	CD
cord-017772-zpf1xjqi	171	1	L	L	NNP
cord-017772-zpf1xjqi	171	2	is	be	VBZ
cord-017772-zpf1xjqi	171	3	recommended	recommend	VBN
cord-017772-zpf1xjqi	171	4	for	for	IN
cord-017772-zpf1xjqi	171	5	patients	patient	NNS
cord-017772-zpf1xjqi	171	6	who	who	WP
cord-017772-zpf1xjqi	171	7	are	be	VBP
cord-017772-zpf1xjqi	171	8	actively	actively	RB
cord-017772-zpf1xjqi	171	9	bleeding	bleed	VBG
cord-017772-zpf1xjqi	171	10	or	or	CC
cord-017772-zpf1xjqi	171	11	undergoing	undergo	VBG
cord-017772-zpf1xjqi	171	12	invasive	invasive	JJ
cord-017772-zpf1xjqi	171	13	procedures	procedure	NNS
cord-017772-zpf1xjqi	171	14	[	[	-LRB-
cord-017772-zpf1xjqi	171	15	65	65	CD
cord-017772-zpf1xjqi	171	16	]	]	-RRB-
cord-017772-zpf1xjqi	171	17	.	.	.
cord-017772-zpf1xjqi	172	1	Dilutional	dilutional	JJ
cord-017772-zpf1xjqi	172	2	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	172	3	is	be	VBZ
cord-017772-zpf1xjqi	172	4	a	a	DT
cord-017772-zpf1xjqi	172	5	well	well	RB
cord-017772-zpf1xjqi	172	6	-	-	HYPH
cord-017772-zpf1xjqi	172	7	recognized	recognize	VBN
cord-017772-zpf1xjqi	172	8	complication	complication	NN
cord-017772-zpf1xjqi	172	9	of	of	IN
cord-017772-zpf1xjqi	172	10	massive	massive	JJ
cord-017772-zpf1xjqi	172	11	transfusion	transfusion	NN
cord-017772-zpf1xjqi	172	12	.	.	.
cord-017772-zpf1xjqi	173	1	The	the	DT
cord-017772-zpf1xjqi	173	2	incidence	incidence	NN
cord-017772-zpf1xjqi	173	3	of	of	IN
cord-017772-zpf1xjqi	173	4	severe	severe	JJ
cord-017772-zpf1xjqi	173	5	thrombocytopenia	thrombocytopenia	NNS
cord-017772-zpf1xjqi	173	6	(	(	-LRB-
cord-017772-zpf1xjqi	173	7	defined	define	VBN
cord-017772-zpf1xjqi	173	8	as	as	IN
cord-017772-zpf1xjqi	173	9	a	a	DT
cord-017772-zpf1xjqi	173	10	platelet	platelet	NN
cord-017772-zpf1xjqi	173	11	count	count	NN
cord-017772-zpf1xjqi	173	12	<	<	XX
cord-017772-zpf1xjqi	173	13	50	50	CD
cord-017772-zpf1xjqi	173	14	×	×	NN
cord-017772-zpf1xjqi	173	15	10	10	CD
cord-017772-zpf1xjqi	173	16	9	9	CD
cord-017772-zpf1xjqi	173	17	cells	cell	NNS
cord-017772-zpf1xjqi	173	18	/	/	SYM
cord-017772-zpf1xjqi	173	19	L	l	NN
cord-017772-zpf1xjqi	173	20	)	)	-RRB-
cord-017772-zpf1xjqi	173	21	may	may	MD
cord-017772-zpf1xjqi	173	22	be	be	VB
cord-017772-zpf1xjqi	173	23	as	as	RB
cord-017772-zpf1xjqi	173	24	high	high	JJ
cord-017772-zpf1xjqi	173	25	as	as	IN
cord-017772-zpf1xjqi	173	26	75	75	CD
cord-017772-zpf1xjqi	173	27	%	%	NN
cord-017772-zpf1xjqi	173	28	when	when	WRB
cord-017772-zpf1xjqi	173	29	patients	patient	NNS
cord-017772-zpf1xjqi	173	30	require	require	VBP
cord-017772-zpf1xjqi	173	31	more	more	JJR
cord-017772-zpf1xjqi	173	32	than	than	IN
cord-017772-zpf1xjqi	173	33	20	20	CD
cord-017772-zpf1xjqi	173	34	red	red	JJ
cord-017772-zpf1xjqi	173	35	blood	blood	NN
cord-017772-zpf1xjqi	173	36	cell	cell	NN
cord-017772-zpf1xjqi	173	37	containing	contain	VBG
cord-017772-zpf1xjqi	173	38	products	product	NNS
cord-017772-zpf1xjqi	173	39	[	[	-LRB-
cord-017772-zpf1xjqi	173	40	66	66	CD
cord-017772-zpf1xjqi	173	41	]	]	-RRB-
cord-017772-zpf1xjqi	173	42	.	.	.
cord-017772-zpf1xjqi	174	1	Prompt	prompt	JJ
cord-017772-zpf1xjqi	174	2	damage	damage	NN
cord-017772-zpf1xjqi	174	3	control	control	NN
cord-017772-zpf1xjqi	174	4	and	and	CC
cord-017772-zpf1xjqi	174	5	transfusion	transfusion	NN
cord-017772-zpf1xjqi	174	6	of	of	IN
cord-017772-zpf1xjqi	174	7	blood	blood	NN
cord-017772-zpf1xjqi	174	8	products	product	NNS
cord-017772-zpf1xjqi	174	9	in	in	IN
cord-017772-zpf1xjqi	174	10	a	a	DT
cord-017772-zpf1xjqi	174	11	balanced	balanced	JJ
cord-017772-zpf1xjqi	174	12	ratio	ratio	NN
cord-017772-zpf1xjqi	174	13	(	(	-LRB-
cord-017772-zpf1xjqi	174	14	1:1:1	1:1:1	CD
cord-017772-zpf1xjqi	174	15	of	of	IN
cord-017772-zpf1xjqi	174	16	red	red	JJ
cord-017772-zpf1xjqi	174	17	blood	blood	NN
cord-017772-zpf1xjqi	174	18	cells	cell	NNS
cord-017772-zpf1xjqi	174	19	:	:	:
cord-017772-zpf1xjqi	174	20	plasma	plasma	NN
cord-017772-zpf1xjqi	174	21	:	:	:
cord-017772-zpf1xjqi	174	22	platelets	platelet	NNS
cord-017772-zpf1xjqi	174	23	)	)	-RRB-
cord-017772-zpf1xjqi	174	24	are	be	VBP
cord-017772-zpf1xjqi	174	25	important	important	JJ
cord-017772-zpf1xjqi	174	26	preventative	preventative	JJ
cord-017772-zpf1xjqi	174	27	strategies	strategy	NNS
cord-017772-zpf1xjqi	174	28	[	[	-LRB-
cord-017772-zpf1xjqi	174	29	67	67	CD
cord-017772-zpf1xjqi	174	30	]	]	-RRB-
cord-017772-zpf1xjqi	174	31	.	.	.
cord-017772-zpf1xjqi	175	1	Step	step	NN
cord-017772-zpf1xjqi	175	2	7	7	CD
cord-017772-zpf1xjqi	175	3	:	:	:
cord-017772-zpf1xjqi	175	4	Evaluate	evaluate	VB
cord-017772-zpf1xjqi	175	5	Support	Support	NNP
cord-017772-zpf1xjqi	175	6	Devices	Devices	NNPS
cord-017772-zpf1xjqi	175	7	Support	Support	NNP
cord-017772-zpf1xjqi	175	8	devices	device	NNS
cord-017772-zpf1xjqi	175	9	used	use	VBN
cord-017772-zpf1xjqi	175	10	in	in	IN
cord-017772-zpf1xjqi	175	11	critically	critically	RB
cord-017772-zpf1xjqi	175	12	ill	ill	JJ
cord-017772-zpf1xjqi	175	13	patients	patient	NNS
cord-017772-zpf1xjqi	175	14	may	may	MD
cord-017772-zpf1xjqi	175	15	lower	lower	VB
cord-017772-zpf1xjqi	175	16	platelet	platelet	NN
cord-017772-zpf1xjqi	175	17	counts	count	NNS
cord-017772-zpf1xjqi	175	18	through	through	IN
cord-017772-zpf1xjqi	175	19	mechanical	mechanical	JJ
cord-017772-zpf1xjqi	175	20	shearing	shearing	NN
cord-017772-zpf1xjqi	175	21	.	.	.
cord-017772-zpf1xjqi	176	1	Veno	Veno	NNP
cord-017772-zpf1xjqi	176	2	-	-	HYPH
cord-017772-zpf1xjqi	176	3	venous	venous	JJ
cord-017772-zpf1xjqi	176	4	extracorporeal	extracorporeal	JJ
cord-017772-zpf1xjqi	176	5	membrane	membrane	NN
cord-017772-zpf1xjqi	176	6	oxygenation	oxygenation	NN
cord-017772-zpf1xjqi	176	7	(	(	-LRB-
cord-017772-zpf1xjqi	176	8	VV	VV	NNP
cord-017772-zpf1xjqi	176	9	-	-	HYPH
cord-017772-zpf1xjqi	176	10	ECMO	ECMO	NNP
cord-017772-zpf1xjqi	176	11	)	)	-RRB-
cord-017772-zpf1xjqi	176	12	is	be	VBZ
cord-017772-zpf1xjqi	176	13	increasingly	increasingly	RB
cord-017772-zpf1xjqi	176	14	utilized	utilize	VBN
cord-017772-zpf1xjqi	176	15	in	in	IN
cord-017772-zpf1xjqi	176	16	the	the	DT
cord-017772-zpf1xjqi	176	17	management	management	NN
cord-017772-zpf1xjqi	176	18	of	of	IN
cord-017772-zpf1xjqi	176	19	severe	severe	JJ
cord-017772-zpf1xjqi	176	20	acute	acute	JJ
cord-017772-zpf1xjqi	176	21	respiratory	respiratory	JJ
cord-017772-zpf1xjqi	176	22	distress	distress	NN
cord-017772-zpf1xjqi	176	23	syndrome	syndrome	NN
cord-017772-zpf1xjqi	176	24	(	(	-LRB-
cord-017772-zpf1xjqi	176	25	ARDS	ARDS	NNP
cord-017772-zpf1xjqi	176	26	)	)	-RRB-
cord-017772-zpf1xjqi	176	27	.	.	.
cord-017772-zpf1xjqi	177	1	In	in	IN
cord-017772-zpf1xjqi	177	2	a	a	DT
cord-017772-zpf1xjqi	177	3	retrospective	retrospective	JJ
cord-017772-zpf1xjqi	177	4	study	study	NN
cord-017772-zpf1xjqi	177	5	of	of	IN
cord-017772-zpf1xjqi	177	6	100	100	CD
cord-017772-zpf1xjqi	177	7	patients	patient	NNS
cord-017772-zpf1xjqi	177	8	placed	place	VBN
cord-017772-zpf1xjqi	177	9	on	on	IN
cord-017772-zpf1xjqi	177	10	VV	VV	NNP
cord-017772-zpf1xjqi	177	11	-	-	HYPH
cord-017772-zpf1xjqi	177	12	ECMO	ECMO	NNP
cord-017772-zpf1xjqi	177	13	for	for	IN
cord-017772-zpf1xjqi	177	14	respiratory	respiratory	JJ
cord-017772-zpf1xjqi	177	15	failure	failure	NN
cord-017772-zpf1xjqi	177	16	,	,	,
cord-017772-zpf1xjqi	177	17	22	22	CD
cord-017772-zpf1xjqi	177	18	%	%	NN
cord-017772-zpf1xjqi	177	19	developed	develop	VBN
cord-017772-zpf1xjqi	177	20	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	177	21	[	[	-LRB-
cord-017772-zpf1xjqi	177	22	68	68	CD
cord-017772-zpf1xjqi	177	23	]	]	-RRB-
cord-017772-zpf1xjqi	177	24	.	.	.
cord-017772-zpf1xjqi	178	1	Severity	severity	NN
cord-017772-zpf1xjqi	178	2	of	of	IN
cord-017772-zpf1xjqi	178	3	illness	illness	NN
cord-017772-zpf1xjqi	178	4	and	and	CC
cord-017772-zpf1xjqi	178	5	the	the	DT
cord-017772-zpf1xjqi	178	6	platelet	platelet	NN
cord-017772-zpf1xjqi	178	7	count	count	NN
cord-017772-zpf1xjqi	178	8	at	at	IN
cord-017772-zpf1xjqi	178	9	the	the	DT
cord-017772-zpf1xjqi	178	10	time	time	NN
cord-017772-zpf1xjqi	178	11	of	of	IN
cord-017772-zpf1xjqi	178	12	cannulation	cannulation	NN
cord-017772-zpf1xjqi	178	13	were	be	VBD
cord-017772-zpf1xjqi	178	14	the	the	DT
cord-017772-zpf1xjqi	178	15	strongest	strong	JJS
cord-017772-zpf1xjqi	178	16	predictors	predictor	NNS
cord-017772-zpf1xjqi	178	17	of	of	IN
cord-017772-zpf1xjqi	178	18	developing	develop	VBG
cord-017772-zpf1xjqi	178	19	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	178	20	.	.	.
cord-017772-zpf1xjqi	179	1	In	in	IN
cord-017772-zpf1xjqi	179	2	a	a	DT
cord-017772-zpf1xjqi	179	3	large	large	JJ
cord-017772-zpf1xjqi	179	4	randomized	randomized	JJ
cord-017772-zpf1xjqi	179	5	trial	trial	NN
cord-017772-zpf1xjqi	179	6	of	of	IN
cord-017772-zpf1xjqi	179	7	ECMO	ECMO	NNP
cord-017772-zpf1xjqi	179	8	for	for	IN
cord-017772-zpf1xjqi	179	9	severe	severe	JJ
cord-017772-zpf1xjqi	179	10	ARDS	ARDS	NNP
cord-017772-zpf1xjqi	179	11	,	,	,
cord-017772-zpf1xjqi	179	12	27	27	CD
cord-017772-zpf1xjqi	179	13	%	%	NN
cord-017772-zpf1xjqi	179	14	of	of	IN
cord-017772-zpf1xjqi	179	15	patients	patient	NNS
cord-017772-zpf1xjqi	179	16	randomized	randomize	VBN
cord-017772-zpf1xjqi	179	17	to	to	IN
cord-017772-zpf1xjqi	179	18	ECMO	ECMO	NNP
cord-017772-zpf1xjqi	179	19	developed	develop	VBN
cord-017772-zpf1xjqi	179	20	Adapted	adapt	VBN
cord-017772-zpf1xjqi	179	21	from	from	IN
cord-017772-zpf1xjqi	179	22	Lo	Lo	NNP
cord-017772-zpf1xjqi	179	23	[	[	-LRB-
cord-017772-zpf1xjqi	179	24	58	58	CD
cord-017772-zpf1xjqi	179	25	]	]	-RRB-
cord-017772-zpf1xjqi	179	26	.	.	.
cord-017772-zpf1xjqi	180	1	A	a	DT
cord-017772-zpf1xjqi	180	2	score	score	NN
cord-017772-zpf1xjqi	180	3	≤	≤	NN
cord-017772-zpf1xjqi	180	4	3	3	CD
cord-017772-zpf1xjqi	180	5	suggests	suggest	VBZ
cord-017772-zpf1xjqi	180	6	a	a	DT
cord-017772-zpf1xjqi	180	7	low	low	JJ
cord-017772-zpf1xjqi	180	8	pre	pre	JJ
cord-017772-zpf1xjqi	180	9	-	-	JJ
cord-017772-zpf1xjqi	180	10	test	test	JJ
cord-017772-zpf1xjqi	180	11	probability	probability	NN
cord-017772-zpf1xjqi	180	12	for	for	IN
cord-017772-zpf1xjqi	180	13	HIT	hit	NN
cord-017772-zpf1xjqi	180	14	,	,	,
cord-017772-zpf1xjqi	180	15	a	a	DT
cord-017772-zpf1xjqi	180	16	score	score	NN
cord-017772-zpf1xjqi	180	17	4	4	CD
cord-017772-zpf1xjqi	180	18	-	-	SYM
cord-017772-zpf1xjqi	180	19	5	5	CD
cord-017772-zpf1xjqi	180	20	an	an	DT
cord-017772-zpf1xjqi	180	21	intermediate	intermediate	JJ
cord-017772-zpf1xjqi	180	22	probability	probability	NN
cord-017772-zpf1xjqi	180	23	,	,	,
cord-017772-zpf1xjqi	180	24	and	and	CC
cord-017772-zpf1xjqi	180	25	a	a	DT
cord-017772-zpf1xjqi	180	26	score	score	NN
cord-017772-zpf1xjqi	180	27	>	>	XX
cord-017772-zpf1xjqi	180	28	5	5	CD
cord-017772-zpf1xjqi	180	29	a	a	DT
cord-017772-zpf1xjqi	180	30	high	high	JJ
cord-017772-zpf1xjqi	180	31	probability	probability	NN
cord-017772-zpf1xjqi	180	32	severe	severe	JJ
cord-017772-zpf1xjqi	180	33	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	180	34	(	(	-LRB-
cord-017772-zpf1xjqi	180	35	defined	define	VBN
cord-017772-zpf1xjqi	180	36	as	as	IN
cord-017772-zpf1xjqi	180	37	a	a	DT
cord-017772-zpf1xjqi	180	38	platelet	platelet	NN
cord-017772-zpf1xjqi	180	39	count	count	NN
cord-017772-zpf1xjqi	180	40	<	<	XX
cord-017772-zpf1xjqi	180	41	20	20	CD
cord-017772-zpf1xjqi	180	42	×	×	NN
cord-017772-zpf1xjqi	180	43	10	10	CD
cord-017772-zpf1xjqi	180	44	9	9	CD
cord-017772-zpf1xjqi	180	45	cells	cell	NNS
cord-017772-zpf1xjqi	180	46	/	/	SYM
cord-017772-zpf1xjqi	180	47	L	L	NNP
cord-017772-zpf1xjqi	180	48	)	)	-RRB-
cord-017772-zpf1xjqi	180	49	vs	vs	IN
cord-017772-zpf1xjqi	180	50	16	16	CD
cord-017772-zpf1xjqi	180	51	%	%	NN
cord-017772-zpf1xjqi	180	52	in	in	IN
cord-017772-zpf1xjqi	180	53	the	the	DT
cord-017772-zpf1xjqi	180	54	control	control	NN
cord-017772-zpf1xjqi	180	55	arm	arm	NN
cord-017772-zpf1xjqi	180	56	[	[	-LRB-
cord-017772-zpf1xjqi	180	57	69	69	CD
cord-017772-zpf1xjqi	180	58	]	]	-RRB-
cord-017772-zpf1xjqi	180	59	.	.	.
cord-017772-zpf1xjqi	181	1	For	for	IN
cord-017772-zpf1xjqi	181	2	patients	patient	NNS
cord-017772-zpf1xjqi	181	3	placed	place	VBN
cord-017772-zpf1xjqi	181	4	on	on	IN
cord-017772-zpf1xjqi	181	5	an	an	DT
cord-017772-zpf1xjqi	181	6	intra	intra	JJ
cord-017772-zpf1xjqi	181	7	-	-	JJ
cord-017772-zpf1xjqi	181	8	aortic	aortic	JJ
cord-017772-zpf1xjqi	181	9	balloon	balloon	NN
cord-017772-zpf1xjqi	181	10	pump	pump	NN
cord-017772-zpf1xjqi	181	11	,	,	,
cord-017772-zpf1xjqi	181	12	roughly	roughly	RB
cord-017772-zpf1xjqi	181	13	50	50	CD
cord-017772-zpf1xjqi	181	14	%	%	NN
cord-017772-zpf1xjqi	181	15	will	will	MD
cord-017772-zpf1xjqi	181	16	develop	develop	VB
cord-017772-zpf1xjqi	181	17	thrombocytopenia	thrombocytopenia	JJ
cord-017772-zpf1xjqi	181	18	[	[	-LRB-
cord-017772-zpf1xjqi	181	19	70	70	CD
cord-017772-zpf1xjqi	181	20	,	,	,
cord-017772-zpf1xjqi	181	21	71	71	CD
cord-017772-zpf1xjqi	181	22	]	]	-RRB-
cord-017772-zpf1xjqi	181	23	.	.	.
cord-017772-zpf1xjqi	182	1	Despite	despite	IN
cord-017772-zpf1xjqi	182	2	the	the	DT
cord-017772-zpf1xjqi	182	3	high	high	JJ
cord-017772-zpf1xjqi	182	4	incidence	incidence	NN
cord-017772-zpf1xjqi	182	5	of	of	IN
cord-017772-zpf1xjqi	182	6	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	182	7	in	in	IN
cord-017772-zpf1xjqi	182	8	critically	critically	RB
cord-017772-zpf1xjqi	182	9	ill	ill	JJ
cord-017772-zpf1xjqi	182	10	patients	patient	NNS
cord-017772-zpf1xjqi	182	11	,	,	,
cord-017772-zpf1xjqi	182	12	there	there	EX
cord-017772-zpf1xjqi	182	13	is	be	VBZ
cord-017772-zpf1xjqi	182	14	a	a	DT
cord-017772-zpf1xjqi	182	15	paucity	paucity	NN
cord-017772-zpf1xjqi	182	16	of	of	IN
cord-017772-zpf1xjqi	182	17	data	datum	NNS
cord-017772-zpf1xjqi	182	18	to	to	TO
cord-017772-zpf1xjqi	182	19	guide	guide	VB
cord-017772-zpf1xjqi	182	20	when	when	WRB
cord-017772-zpf1xjqi	182	21	prophylactic	prophylactic	JJ
cord-017772-zpf1xjqi	182	22	platelet	platelet	NN
cord-017772-zpf1xjqi	182	23	transfusion	transfusion	NN
cord-017772-zpf1xjqi	182	24	is	be	VBZ
cord-017772-zpf1xjqi	182	25	indicated	indicate	VBN
cord-017772-zpf1xjqi	182	26	.	.	.
cord-017772-zpf1xjqi	183	1	Indeed	indeed	RB
cord-017772-zpf1xjqi	183	2	,	,	,
cord-017772-zpf1xjqi	183	3	a	a	DT
cord-017772-zpf1xjqi	183	4	recent	recent	JJ
cord-017772-zpf1xjqi	183	5	systematic	systematic	JJ
cord-017772-zpf1xjqi	183	6	review	review	NN
cord-017772-zpf1xjqi	183	7	did	do	VBD
cord-017772-zpf1xjqi	183	8	not	not	RB
cord-017772-zpf1xjqi	183	9	identify	identify	VB
cord-017772-zpf1xjqi	183	10	a	a	DT
cord-017772-zpf1xjqi	183	11	single	single	JJ
cord-017772-zpf1xjqi	183	12	high	high	JJ
cord-017772-zpf1xjqi	183	13	-	-	HYPH
cord-017772-zpf1xjqi	183	14	quality	quality	NN
cord-017772-zpf1xjqi	183	15	study	study	NN
cord-017772-zpf1xjqi	183	16	that	that	WDT
cord-017772-zpf1xjqi	183	17	investigated	investigate	VBD
cord-017772-zpf1xjqi	183	18	the	the	DT
cord-017772-zpf1xjqi	183	19	impact	impact	NN
cord-017772-zpf1xjqi	183	20	of	of	IN
cord-017772-zpf1xjqi	183	21	prophylactic	prophylactic	JJ
cord-017772-zpf1xjqi	183	22	platelet	platelet	NN
cord-017772-zpf1xjqi	183	23	transfusions	transfusion	NNS
cord-017772-zpf1xjqi	183	24	on	on	IN
cord-017772-zpf1xjqi	183	25	bleeding	bleed	VBG
cord-017772-zpf1xjqi	183	26	rates	rate	NNS
cord-017772-zpf1xjqi	183	27	in	in	IN
cord-017772-zpf1xjqi	183	28	critically	critically	RB
cord-017772-zpf1xjqi	183	29	ill	ill	JJ
cord-017772-zpf1xjqi	183	30	patients	patient	NNS
cord-017772-zpf1xjqi	183	31	[	[	-LRB-
cord-017772-zpf1xjqi	183	32	72	72	CD
cord-017772-zpf1xjqi	183	33	]	]	-RRB-
cord-017772-zpf1xjqi	183	34	.	.	.
cord-017772-zpf1xjqi	184	1	Recommendations	recommendation	NNS
cord-017772-zpf1xjqi	184	2	on	on	IN
cord-017772-zpf1xjqi	184	3	prophylactic	prophylactic	JJ
cord-017772-zpf1xjqi	184	4	platelet	platelet	NN
cord-017772-zpf1xjqi	184	5	transfusions	transfusion	NNS
cord-017772-zpf1xjqi	184	6	in	in	IN
cord-017772-zpf1xjqi	184	7	critically	critically	RB
cord-017772-zpf1xjqi	184	8	ill	ill	JJ
cord-017772-zpf1xjqi	184	9	patients	patient	NNS
cord-017772-zpf1xjqi	184	10	are	be	VBP
cord-017772-zpf1xjqi	184	11	largely	largely	RB
cord-017772-zpf1xjqi	184	12	extrapolated	extrapolate	VBN
cord-017772-zpf1xjqi	184	13	from	from	IN
cord-017772-zpf1xjqi	184	14	studies	study	NNS
cord-017772-zpf1xjqi	184	15	in	in	IN
cord-017772-zpf1xjqi	184	16	patients	patient	NNS
cord-017772-zpf1xjqi	184	17	with	with	IN
cord-017772-zpf1xjqi	184	18	hematologic	hematologic	JJ
cord-017772-zpf1xjqi	184	19	malignancies	malignancy	NNS
cord-017772-zpf1xjqi	184	20	.	.	.
cord-017772-zpf1xjqi	185	1	In	in	IN
cord-017772-zpf1xjqi	185	2	a	a	DT
cord-017772-zpf1xjqi	185	3	landmark	landmark	JJ
cord-017772-zpf1xjqi	185	4	trial	trial	NN
cord-017772-zpf1xjqi	185	5	of	of	IN
cord-017772-zpf1xjqi	185	6	platelet	platelet	NN
cord-017772-zpf1xjqi	185	7	transfusion	transfusion	NN
cord-017772-zpf1xjqi	185	8	thresholds	threshold	NNS
cord-017772-zpf1xjqi	185	9	in	in	IN
cord-017772-zpf1xjqi	185	10	255	255	CD
cord-017772-zpf1xjqi	185	11	patients	patient	NNS
cord-017772-zpf1xjqi	185	12	with	with	IN
cord-017772-zpf1xjqi	185	13	acute	acute	JJ
cord-017772-zpf1xjqi	185	14	myeloid	myeloid	NN
cord-017772-zpf1xjqi	185	15	leukemia	leukemia	NN
cord-017772-zpf1xjqi	185	16	undergoing	undergo	VBG
cord-017772-zpf1xjqi	185	17	induction	induction	NN
cord-017772-zpf1xjqi	185	18	chemotherapy	chemotherapy	NN
cord-017772-zpf1xjqi	185	19	,	,	,
cord-017772-zpf1xjqi	185	20	a	a	DT
cord-017772-zpf1xjqi	185	21	transfusion	transfusion	NN
cord-017772-zpf1xjqi	185	22	threshold	threshold	NN
cord-017772-zpf1xjqi	185	23	of	of	IN
cord-017772-zpf1xjqi	185	24	10	10	CD
cord-017772-zpf1xjqi	185	25	×	×	NN
cord-017772-zpf1xjqi	185	26	10	10	CD
cord-017772-zpf1xjqi	185	27	9	9	CD
cord-017772-zpf1xjqi	185	28	cells	cell	NNS
cord-017772-zpf1xjqi	185	29	/	/	SYM
cord-017772-zpf1xjqi	185	30	L	L	NNP
cord-017772-zpf1xjqi	185	31	did	do	VBD
cord-017772-zpf1xjqi	185	32	not	not	RB
cord-017772-zpf1xjqi	185	33	increase	increase	VB
cord-017772-zpf1xjqi	185	34	the	the	DT
cord-017772-zpf1xjqi	185	35	risk	risk	NN
cord-017772-zpf1xjqi	185	36	of	of	IN
cord-017772-zpf1xjqi	185	37	major	major	JJ
cord-017772-zpf1xjqi	185	38	bleeding	bleeding	NN
cord-017772-zpf1xjqi	185	39	and	and	CC
cord-017772-zpf1xjqi	185	40	reduced	reduce	VBD
cord-017772-zpf1xjqi	185	41	the	the	DT
cord-017772-zpf1xjqi	185	42	need	need	NN
cord-017772-zpf1xjqi	185	43	for	for	IN
cord-017772-zpf1xjqi	185	44	platelet	platelet	NN
cord-017772-zpf1xjqi	185	45	transfusions	transfusion	NNS
cord-017772-zpf1xjqi	185	46	by	by	IN
cord-017772-zpf1xjqi	185	47	21.5	21.5	CD
cord-017772-zpf1xjqi	185	48	%	%	NN
cord-017772-zpf1xjqi	185	49	compared	compare	VBN
cord-017772-zpf1xjqi	185	50	to	to	IN
cord-017772-zpf1xjqi	185	51	a	a	DT
cord-017772-zpf1xjqi	185	52	threshold	threshold	NN
cord-017772-zpf1xjqi	185	53	of	of	IN
cord-017772-zpf1xjqi	185	54	20	20	CD
cord-017772-zpf1xjqi	185	55	×	×	NN
cord-017772-zpf1xjqi	185	56	10	10	CD
cord-017772-zpf1xjqi	185	57	9	9	CD
cord-017772-zpf1xjqi	185	58	cells	cell	NNS
cord-017772-zpf1xjqi	185	59	/	/	SYM
cord-017772-zpf1xjqi	185	60	L.	L.	NNP
cord-017772-zpf1xjqi	185	61	[	[	-LRB-
cord-017772-zpf1xjqi	185	62	73	73	CD
cord-017772-zpf1xjqi	185	63	]	]	-RRB-
cord-017772-zpf1xjqi	186	1	A	a	DT
cord-017772-zpf1xjqi	186	2	recent	recent	JJ
cord-017772-zpf1xjqi	186	3	Cochrane	Cochrane	NNP
cord-017772-zpf1xjqi	186	4	review	review	NN
cord-017772-zpf1xjqi	186	5	supports	support	VBZ
cord-017772-zpf1xjqi	186	6	the	the	DT
cord-017772-zpf1xjqi	186	7	conclusion	conclusion	NN
cord-017772-zpf1xjqi	186	8	that	that	IN
cord-017772-zpf1xjqi	186	9	a	a	DT
cord-017772-zpf1xjqi	186	10	restrictive	restrictive	JJ
cord-017772-zpf1xjqi	186	11	platelet	platelet	NN
cord-017772-zpf1xjqi	186	12	transfusion	transfusion	NN
cord-017772-zpf1xjqi	186	13	threshold	threshold	NN
cord-017772-zpf1xjqi	186	14	is	be	VBZ
cord-017772-zpf1xjqi	186	15	safe	safe	JJ
cord-017772-zpf1xjqi	186	16	in	in	IN
cord-017772-zpf1xjqi	186	17	patients	patient	NNS
cord-017772-zpf1xjqi	186	18	with	with	IN
cord-017772-zpf1xjqi	186	19	hematologic	hematologic	JJ
cord-017772-zpf1xjqi	186	20	malignancies	malignancy	NNS
cord-017772-zpf1xjqi	186	21	[	[	-LRB-
cord-017772-zpf1xjqi	186	22	74	74	CD
cord-017772-zpf1xjqi	186	23	]	]	-RRB-
cord-017772-zpf1xjqi	186	24	.	.	.
cord-017772-zpf1xjqi	187	1	Guidelines	guideline	NNS
cord-017772-zpf1xjqi	187	2	by	by	IN
cord-017772-zpf1xjqi	187	3	the	the	DT
cord-017772-zpf1xjqi	187	4	American	American	NNP
cord-017772-zpf1xjqi	187	5	Society	Society	NNP
cord-017772-zpf1xjqi	187	6	of	of	IN
cord-017772-zpf1xjqi	187	7	Clinical	Clinical	NNP
cord-017772-zpf1xjqi	187	8	Oncology	Oncology	NNP
cord-017772-zpf1xjqi	187	9	recommend	recommend	VBP
cord-017772-zpf1xjqi	187	10	a	a	DT
cord-017772-zpf1xjqi	187	11	prophylactic	prophylactic	JJ
cord-017772-zpf1xjqi	187	12	platelet	platelet	NN
cord-017772-zpf1xjqi	187	13	transfusion	transfusion	NN
cord-017772-zpf1xjqi	187	14	threshold	threshold	NN
cord-017772-zpf1xjqi	187	15	of	of	IN
cord-017772-zpf1xjqi	187	16	10	10	CD
cord-017772-zpf1xjqi	187	17	×	×	NN
cord-017772-zpf1xjqi	187	18	10	10	CD
cord-017772-zpf1xjqi	187	19	9	9	CD
cord-017772-zpf1xjqi	187	20	cells	cell	NNS
cord-017772-zpf1xjqi	187	21	/	/	SYM
cord-017772-zpf1xjqi	187	22	L	l	NN
cord-017772-zpf1xjqi	187	23	in	in	IN
cord-017772-zpf1xjqi	187	24	patients	patient	NNS
cord-017772-zpf1xjqi	187	25	with	with	IN
cord-017772-zpf1xjqi	187	26	malignancy	malignancy	NN
cord-017772-zpf1xjqi	187	27	[	[	-LRB-
cord-017772-zpf1xjqi	187	28	75	75	CD
cord-017772-zpf1xjqi	187	29	]	]	-RRB-
cord-017772-zpf1xjqi	187	30	.	.	.
cord-017772-zpf1xjqi	188	1	It	-PRON-	PRP
cord-017772-zpf1xjqi	188	2	is	be	VBZ
cord-017772-zpf1xjqi	188	3	unclear	unclear	JJ
cord-017772-zpf1xjqi	188	4	,	,	,
cord-017772-zpf1xjqi	188	5	however	however	RB
cord-017772-zpf1xjqi	188	6	,	,	,
cord-017772-zpf1xjqi	188	7	if	if	IN
cord-017772-zpf1xjqi	188	8	data	datum	NNS
cord-017772-zpf1xjqi	188	9	from	from	IN
cord-017772-zpf1xjqi	188	10	patients	patient	NNS
cord-017772-zpf1xjqi	188	11	with	with	IN
cord-017772-zpf1xjqi	188	12	malignancies	malignancy	NNS
cord-017772-zpf1xjqi	188	13	can	can	MD
cord-017772-zpf1xjqi	188	14	be	be	VB
cord-017772-zpf1xjqi	188	15	reliably	reliably	RB
cord-017772-zpf1xjqi	188	16	generalized	generalize	VBN
cord-017772-zpf1xjqi	188	17	to	to	IN
cord-017772-zpf1xjqi	188	18	the	the	DT
cord-017772-zpf1xjqi	188	19	heterogeneous	heterogeneous	JJ
cord-017772-zpf1xjqi	188	20	group	group	NN
cord-017772-zpf1xjqi	188	21	of	of	IN
cord-017772-zpf1xjqi	188	22	patients	patient	NNS
cord-017772-zpf1xjqi	188	23	cared	care	VBN
cord-017772-zpf1xjqi	188	24	for	for	IN
cord-017772-zpf1xjqi	188	25	in	in	IN
cord-017772-zpf1xjqi	188	26	the	the	DT
cord-017772-zpf1xjqi	188	27	ICU	ICU	NNP
cord-017772-zpf1xjqi	188	28	[	[	-LRB-
cord-017772-zpf1xjqi	188	29	76	76	CD
cord-017772-zpf1xjqi	188	30	]	]	-RRB-
cord-017772-zpf1xjqi	188	31	.	.	.
cord-017772-zpf1xjqi	189	1	Some	some	DT
cord-017772-zpf1xjqi	189	2	have	have	VBP
cord-017772-zpf1xjqi	189	3	advocated	advocate	VBN
cord-017772-zpf1xjqi	189	4	for	for	IN
cord-017772-zpf1xjqi	189	5	an	an	DT
cord-017772-zpf1xjqi	189	6	approach	approach	NN
cord-017772-zpf1xjqi	189	7	which	which	WDT
cord-017772-zpf1xjqi	189	8	reserves	reserve	VBZ
cord-017772-zpf1xjqi	189	9	platelet	platelet	NN
cord-017772-zpf1xjqi	189	10	transfusions	transfusion	NNS
cord-017772-zpf1xjqi	189	11	for	for	IN
cord-017772-zpf1xjqi	189	12	critically	critically	RB
cord-017772-zpf1xjqi	189	13	ill	ill	JJ
cord-017772-zpf1xjqi	189	14	patients	patient	NNS
cord-017772-zpf1xjqi	189	15	with	with	IN
cord-017772-zpf1xjqi	189	16	clinical	clinical	JJ
cord-017772-zpf1xjqi	189	17	evidence	evidence	NN
cord-017772-zpf1xjqi	189	18	of	of	IN
cord-017772-zpf1xjqi	189	19	bleeding	bleed	VBG
cord-017772-zpf1xjqi	189	20	(	(	-LRB-
cord-017772-zpf1xjqi	189	21	regardless	regardless	RB
cord-017772-zpf1xjqi	189	22	of	of	IN
cord-017772-zpf1xjqi	189	23	the	the	DT
cord-017772-zpf1xjqi	189	24	actual	actual	JJ
cord-017772-zpf1xjqi	189	25	platelet	platelet	NN
cord-017772-zpf1xjqi	189	26	count	count	NN
cord-017772-zpf1xjqi	189	27	)	)	-RRB-
cord-017772-zpf1xjqi	190	1	[	[	-LRB-
cord-017772-zpf1xjqi	190	2	48	48	CD
cord-017772-zpf1xjqi	190	3	]	]	-RRB-
cord-017772-zpf1xjqi	190	4	.	.	.
cord-017772-zpf1xjqi	191	1	However	however	RB
cord-017772-zpf1xjqi	191	2	,	,	,
cord-017772-zpf1xjqi	191	3	there	there	EX
cord-017772-zpf1xjqi	191	4	is	be	VBZ
cord-017772-zpf1xjqi	191	5	insufficient	insufficient	JJ
cord-017772-zpf1xjqi	191	6	data	datum	NNS
cord-017772-zpf1xjqi	191	7	to	to	TO
cord-017772-zpf1xjqi	191	8	support	support	VB
cord-017772-zpf1xjqi	191	9	the	the	DT
cord-017772-zpf1xjqi	191	10	safety	safety	NN
cord-017772-zpf1xjqi	191	11	or	or	CC
cord-017772-zpf1xjqi	191	12	efficacy	efficacy	NN
cord-017772-zpf1xjqi	191	13	of	of	IN
cord-017772-zpf1xjqi	191	14	this	this	DT
cord-017772-zpf1xjqi	191	15	practice	practice	NN
cord-017772-zpf1xjqi	191	16	.	.	.
cord-017772-zpf1xjqi	192	1	There	there	EX
cord-017772-zpf1xjqi	192	2	is	be	VBZ
cord-017772-zpf1xjqi	192	3	equally	equally	RB
cord-017772-zpf1xjqi	192	4	limited	limited	JJ
cord-017772-zpf1xjqi	192	5	evidence	evidence	NN
cord-017772-zpf1xjqi	192	6	to	to	TO
cord-017772-zpf1xjqi	192	7	guide	guide	VB
cord-017772-zpf1xjqi	192	8	the	the	DT
cord-017772-zpf1xjqi	192	9	platelet	platelet	NN
cord-017772-zpf1xjqi	192	10	count	count	NN
cord-017772-zpf1xjqi	192	11	needed	need	VBN
cord-017772-zpf1xjqi	192	12	to	to	TO
cord-017772-zpf1xjqi	192	13	limit	limit	VB
cord-017772-zpf1xjqi	192	14	bleeding	bleed	VBG
cord-017772-zpf1xjqi	192	15	complications	complication	NNS
cord-017772-zpf1xjqi	192	16	during	during	IN
cord-017772-zpf1xjqi	192	17	bedside	bedside	NN
cord-017772-zpf1xjqi	192	18	procedures	procedure	NNS
cord-017772-zpf1xjqi	192	19	commonly	commonly	RB
cord-017772-zpf1xjqi	192	20	performed	perform	VBN
cord-017772-zpf1xjqi	192	21	in	in	IN
cord-017772-zpf1xjqi	192	22	the	the	DT
cord-017772-zpf1xjqi	192	23	ICU	ICU	NNP
cord-017772-zpf1xjqi	192	24	.	.	.
cord-017772-zpf1xjqi	193	1	The	the	DT
cord-017772-zpf1xjqi	193	2	American	American	NNP
cord-017772-zpf1xjqi	193	3	Association	Association	NNP
cord-017772-zpf1xjqi	193	4	of	of	IN
cord-017772-zpf1xjqi	193	5	Blood	Blood	NNP
cord-017772-zpf1xjqi	193	6	Banks	Banks	NNPS
cord-017772-zpf1xjqi	193	7	recommends	recommend	VBZ
cord-017772-zpf1xjqi	193	8	a	a	DT
cord-017772-zpf1xjqi	193	9	platelet	platelet	NN
cord-017772-zpf1xjqi	193	10	threshold	threshold	NN
cord-017772-zpf1xjqi	193	11	of	of	IN
cord-017772-zpf1xjqi	193	12	20	20	CD
cord-017772-zpf1xjqi	193	13	×	×	NN
cord-017772-zpf1xjqi	193	14	10	10	CD
cord-017772-zpf1xjqi	193	15	9	9	CD
cord-017772-zpf1xjqi	193	16	cells	cell	NNS
cord-017772-zpf1xjqi	193	17	/	/	SYM
cord-017772-zpf1xjqi	193	18	L	l	NN
cord-017772-zpf1xjqi	193	19	for	for	IN
cord-017772-zpf1xjqi	193	20	patients	patient	NNS
cord-017772-zpf1xjqi	193	21	undergoing	undergo	VBG
cord-017772-zpf1xjqi	193	22	central	central	JJ
cord-017772-zpf1xjqi	193	23	line	line	NN
cord-017772-zpf1xjqi	193	24	insertion	insertion	NN
cord-017772-zpf1xjqi	193	25	and	and	CC
cord-017772-zpf1xjqi	193	26	50	50	CD
cord-017772-zpf1xjqi	193	27	×	×	NN
cord-017772-zpf1xjqi	193	28	10	10	CD
cord-017772-zpf1xjqi	193	29	9	9	CD
cord-017772-zpf1xjqi	193	30	cells	cell	NNS
cord-017772-zpf1xjqi	193	31	/	/	SYM
cord-017772-zpf1xjqi	193	32	L	l	NN
cord-017772-zpf1xjqi	193	33	for	for	IN
cord-017772-zpf1xjqi	193	34	patients	patient	NNS
cord-017772-zpf1xjqi	193	35	undergoing	undergo	VBG
cord-017772-zpf1xjqi	193	36	lumbar	lumbar	JJ
cord-017772-zpf1xjqi	193	37	puncture	puncture	NN
cord-017772-zpf1xjqi	193	38	although	although	IN
cord-017772-zpf1xjqi	193	39	both	both	DT
cord-017772-zpf1xjqi	193	40	are	be	VBP
cord-017772-zpf1xjqi	193	41	weak	weak	JJ
cord-017772-zpf1xjqi	193	42	recommendations	recommendation	NNS
cord-017772-zpf1xjqi	193	43	supported	support	VBN
cord-017772-zpf1xjqi	193	44	by	by	IN
cord-017772-zpf1xjqi	193	45	low	low	JJ
cord-017772-zpf1xjqi	193	46	-	-	HYPH
cord-017772-zpf1xjqi	193	47	quality	quality	NN
cord-017772-zpf1xjqi	193	48	evidence	evidence	NN
cord-017772-zpf1xjqi	193	49	[	[	-LRB-
cord-017772-zpf1xjqi	193	50	77	77	CD
cord-017772-zpf1xjqi	193	51	]	]	-RRB-
cord-017772-zpf1xjqi	193	52	.	.	.
cord-017772-zpf1xjqi	194	1	A	a	DT
cord-017772-zpf1xjqi	194	2	recent	recent	JJ
cord-017772-zpf1xjqi	194	3	Cochrane	Cochrane	NNP
cord-017772-zpf1xjqi	194	4	review	review	NN
cord-017772-zpf1xjqi	194	5	of	of	IN
cord-017772-zpf1xjqi	194	6	platelet	platelet	NN
cord-017772-zpf1xjqi	194	7	thresholds	threshold	NNS
cord-017772-zpf1xjqi	194	8	for	for	IN
cord-017772-zpf1xjqi	194	9	patients	patient	NNS
cord-017772-zpf1xjqi	194	10	undergoing	undergo	VBG
cord-017772-zpf1xjqi	194	11	central	central	JJ
cord-017772-zpf1xjqi	194	12	line	line	NN
cord-017772-zpf1xjqi	194	13	insertion	insertion	NN
cord-017772-zpf1xjqi	194	14	was	be	VBD
cord-017772-zpf1xjqi	194	15	unable	unable	JJ
cord-017772-zpf1xjqi	194	16	to	to	TO
cord-017772-zpf1xjqi	194	17	draw	draw	VB
cord-017772-zpf1xjqi	194	18	any	any	DT
cord-017772-zpf1xjqi	194	19	conclusions	conclusion	NNS
cord-017772-zpf1xjqi	194	20	given	give	VBN
cord-017772-zpf1xjqi	194	21	the	the	DT
cord-017772-zpf1xjqi	194	22	complete	complete	JJ
cord-017772-zpf1xjqi	194	23	lack	lack	NN
cord-017772-zpf1xjqi	194	24	of	of	IN
cord-017772-zpf1xjqi	194	25	data	datum	NNS
cord-017772-zpf1xjqi	194	26	on	on	IN
cord-017772-zpf1xjqi	194	27	the	the	DT
cord-017772-zpf1xjqi	194	28	subject	subject	NN
cord-017772-zpf1xjqi	194	29	[	[	-LRB-
cord-017772-zpf1xjqi	194	30	78	78	CD
cord-017772-zpf1xjqi	194	31	]	]	-RRB-
cord-017772-zpf1xjqi	194	32	.	.	.
cord-017772-zpf1xjqi	195	1	There	there	EX
cord-017772-zpf1xjqi	195	2	is	be	VBZ
cord-017772-zpf1xjqi	195	3	mounting	mount	VBG
cord-017772-zpf1xjqi	195	4	evidence	evidence	NN
cord-017772-zpf1xjqi	195	5	that	that	IN
cord-017772-zpf1xjqi	195	6	thoracentesis	thoracentesis	NN
cord-017772-zpf1xjqi	195	7	can	can	MD
cord-017772-zpf1xjqi	195	8	be	be	VB
cord-017772-zpf1xjqi	195	9	safely	safely	RB
cord-017772-zpf1xjqi	195	10	performed	perform	VBN
cord-017772-zpf1xjqi	195	11	by	by	IN
cord-017772-zpf1xjqi	195	12	an	an	DT
cord-017772-zpf1xjqi	195	13	experienced	experienced	JJ
cord-017772-zpf1xjqi	195	14	operator	operator	NN
cord-017772-zpf1xjqi	195	15	in	in	IN
cord-017772-zpf1xjqi	195	16	thrombocytopenic	thrombocytopenic	JJ
cord-017772-zpf1xjqi	195	17	patients	patient	NNS
cord-017772-zpf1xjqi	195	18	without	without	IN
cord-017772-zpf1xjqi	195	19	prophylactic	prophylactic	JJ
cord-017772-zpf1xjqi	195	20	platelet	platelet	NN
cord-017772-zpf1xjqi	195	21	transfusions	transfusion	NNS
cord-017772-zpf1xjqi	195	22	[	[	-LRB-
cord-017772-zpf1xjqi	195	23	79	79	CD
cord-017772-zpf1xjqi	195	24	]	]	-RRB-
cord-017772-zpf1xjqi	195	25	.	.	.
cord-017772-zpf1xjqi	196	1	Platelet	platelet	NN
cord-017772-zpf1xjqi	196	2	biology	biology	NN
cord-017772-zpf1xjqi	196	3	and	and	CC
cord-017772-zpf1xjqi	196	4	functions	function	NNS
cord-017772-zpf1xjqi	196	5	:	:	:
cord-017772-zpf1xjqi	196	6	new	new	JJ
cord-017772-zpf1xjqi	196	7	concepts	concept	NNS
cord-017772-zpf1xjqi	196	8	and	and	CC
cord-017772-zpf1xjqi	196	9	clinical	clinical	JJ
cord-017772-zpf1xjqi	196	10	perspectives	perspective	NNS
cord-017772-zpf1xjqi	197	1	Beyond	beyond	IN
cord-017772-zpf1xjqi	197	2	thrombosis	thrombosis	NN
cord-017772-zpf1xjqi	197	3	:	:	:
cord-017772-zpf1xjqi	197	4	the	the	DT
cord-017772-zpf1xjqi	197	5	versatile	versatile	JJ
cord-017772-zpf1xjqi	197	6	platelet	platelet	NN
cord-017772-zpf1xjqi	197	7	in	in	IN
cord-017772-zpf1xjqi	197	8	critical	critical	JJ
cord-017772-zpf1xjqi	197	9	illness	illness	NN
cord-017772-zpf1xjqi	197	10	Platelets	platelet	NNS
cord-017772-zpf1xjqi	197	11	and	and	CC
cord-017772-zpf1xjqi	197	12	the	the	DT
cord-017772-zpf1xjqi	197	13	immune	immune	JJ
cord-017772-zpf1xjqi	197	14	continuum	continuum	NN
cord-017772-zpf1xjqi	197	15	Coagulopathy	Coagulopathy	NNP
cord-017772-zpf1xjqi	197	16	in	in	IN
cord-017772-zpf1xjqi	197	17	critically	critically	RB
cord-017772-zpf1xjqi	197	18	ill	ill	JJ
cord-017772-zpf1xjqi	197	19	patients	patient	NNS
cord-017772-zpf1xjqi	197	20	:	:	:
cord-017772-zpf1xjqi	197	21	part	part	NN
cord-017772-zpf1xjqi	197	22	1	1	CD
cord-017772-zpf1xjqi	197	23	:	:	:
cord-017772-zpf1xjqi	197	24	platelet	platelet	NN
cord-017772-zpf1xjqi	197	25	disorders	disorder	NNS
cord-017772-zpf1xjqi	197	26	Thrombocytopenic	thrombocytopenic	JJ
cord-017772-zpf1xjqi	197	27	disorders	disorder	NNS
cord-017772-zpf1xjqi	197	28	in	in	IN
cord-017772-zpf1xjqi	197	29	critically	critically	RB
cord-017772-zpf1xjqi	197	30	ill	ill	JJ
cord-017772-zpf1xjqi	197	31	patients	patient	NNS
cord-017772-zpf1xjqi	198	1	Time	time	NN
cord-017772-zpf1xjqi	198	2	course	course	NN
cord-017772-zpf1xjqi	198	3	of	of	IN
cord-017772-zpf1xjqi	198	4	platelet	platelet	NN
cord-017772-zpf1xjqi	198	5	counts	count	NNS
cord-017772-zpf1xjqi	198	6	in	in	IN
cord-017772-zpf1xjqi	198	7	critically	critically	RB
cord-017772-zpf1xjqi	198	8	ill	ill	JJ
cord-017772-zpf1xjqi	198	9	patients	patient	NNS
cord-017772-zpf1xjqi	198	10	Thrombocytopenia	Thrombocytopenia	NNP
cord-017772-zpf1xjqi	198	11	in	in	IN
cord-017772-zpf1xjqi	198	12	medical	medical	JJ
cord-017772-zpf1xjqi	198	13	-	-	HYPH
cord-017772-zpf1xjqi	198	14	surgical	surgical	JJ
cord-017772-zpf1xjqi	198	15	critically	critically	RB
cord-017772-zpf1xjqi	198	16	ill	ill	JJ
cord-017772-zpf1xjqi	198	17	patients	patient	NNS
cord-017772-zpf1xjqi	198	18	:	:	:
cord-017772-zpf1xjqi	199	1	prevalence	prevalence	NN
cord-017772-zpf1xjqi	199	2	,	,	,
cord-017772-zpf1xjqi	199	3	incidence	incidence	NN
cord-017772-zpf1xjqi	199	4	,	,	,
cord-017772-zpf1xjqi	199	5	and	and	CC
cord-017772-zpf1xjqi	199	6	risk	risk	NN
cord-017772-zpf1xjqi	199	7	factors	factor	NNS
cord-017772-zpf1xjqi	199	8	Thrombocytopenia	Thrombocytopenia	NNP
cord-017772-zpf1xjqi	199	9	in	in	IN
cord-017772-zpf1xjqi	199	10	critically	critically	RB
cord-017772-zpf1xjqi	199	11	ill	ill	JJ
cord-017772-zpf1xjqi	199	12	patients	patient	NNS
cord-017772-zpf1xjqi	199	13	receiving	receive	VBG
cord-017772-zpf1xjqi	199	14	thromboprophylaxis	thromboprophylaxis	NN
cord-017772-zpf1xjqi	199	15	:	:	:
cord-017772-zpf1xjqi	199	16	frequency	frequency	NN
cord-017772-zpf1xjqi	199	17	,	,	,
cord-017772-zpf1xjqi	199	18	risk	risk	NN
cord-017772-zpf1xjqi	199	19	factors	factor	NNS
cord-017772-zpf1xjqi	199	20	,	,	,
cord-017772-zpf1xjqi	199	21	and	and	CC
cord-017772-zpf1xjqi	199	22	outcomes	outcome	NNS
cord-017772-zpf1xjqi	199	23	The	the	DT
cord-017772-zpf1xjqi	199	24	frequency	frequency	NN
cord-017772-zpf1xjqi	199	25	and	and	CC
cord-017772-zpf1xjqi	199	26	clinical	clinical	JJ
cord-017772-zpf1xjqi	199	27	significance	significance	NN
cord-017772-zpf1xjqi	199	28	of	of	IN
cord-017772-zpf1xjqi	199	29	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	199	30	complicating	complicate	VBG
cord-017772-zpf1xjqi	199	31	critical	critical	JJ
cord-017772-zpf1xjqi	199	32	illness	illness	NN
cord-017772-zpf1xjqi	199	33	:	:	:
cord-017772-zpf1xjqi	199	34	a	a	DT
cord-017772-zpf1xjqi	199	35	systematic	systematic	JJ
cord-017772-zpf1xjqi	199	36	review	review	NN
cord-017772-zpf1xjqi	199	37	Thrombocytopenia	Thrombocytopenia	NNP
cord-017772-zpf1xjqi	199	38	in	in	IN
cord-017772-zpf1xjqi	199	39	the	the	DT
cord-017772-zpf1xjqi	199	40	intensive	intensive	JJ
cord-017772-zpf1xjqi	199	41	care	care	NN
cord-017772-zpf1xjqi	199	42	unit	unit	NN
cord-017772-zpf1xjqi	199	43	Thrombocytopenia	Thrombocytopenia	NNP
cord-017772-zpf1xjqi	199	44	in	in	IN
cord-017772-zpf1xjqi	199	45	patients	patient	NNS
cord-017772-zpf1xjqi	199	46	in	in	IN
cord-017772-zpf1xjqi	199	47	the	the	DT
cord-017772-zpf1xjqi	199	48	medical	medical	JJ
cord-017772-zpf1xjqi	199	49	intensive	intensive	JJ
cord-017772-zpf1xjqi	199	50	care	care	NN
cord-017772-zpf1xjqi	199	51	unit	unit	NN
cord-017772-zpf1xjqi	199	52	:	:	:
cord-017772-zpf1xjqi	199	53	bleeding	bleed	VBG
cord-017772-zpf1xjqi	199	54	prevalence	prevalence	NN
cord-017772-zpf1xjqi	199	55	,	,	,
cord-017772-zpf1xjqi	199	56	transfusion	transfusion	NN
cord-017772-zpf1xjqi	199	57	requirements	requirement	NNS
cord-017772-zpf1xjqi	199	58	,	,	,
cord-017772-zpf1xjqi	199	59	and	and	CC
cord-017772-zpf1xjqi	199	60	outcome	outcome	NN
cord-017772-zpf1xjqi	199	61	Thrombocytopenia	Thrombocytopenia	NNP
cord-017772-zpf1xjqi	199	62	and	and	CC
cord-017772-zpf1xjqi	199	63	prognosis	prognosis	NN
cord-017772-zpf1xjqi	199	64	in	in	IN
cord-017772-zpf1xjqi	199	65	intensive	intensive	JJ
cord-017772-zpf1xjqi	199	66	care	care	NN
cord-017772-zpf1xjqi	199	67	Platelet	platelet	NN
cord-017772-zpf1xjqi	199	68	count	count	NN
cord-017772-zpf1xjqi	199	69	decline	decline	NN
cord-017772-zpf1xjqi	199	70	:	:	:
cord-017772-zpf1xjqi	199	71	an	an	DT
cord-017772-zpf1xjqi	199	72	early	early	JJ
cord-017772-zpf1xjqi	199	73	prognostic	prognostic	JJ
cord-017772-zpf1xjqi	199	74	marker	marker	NN
cord-017772-zpf1xjqi	199	75	in	in	IN
cord-017772-zpf1xjqi	199	76	critically	critically	RB
cord-017772-zpf1xjqi	199	77	ill	ill	JJ
cord-017772-zpf1xjqi	199	78	patients	patient	NNS
cord-017772-zpf1xjqi	199	79	with	with	IN
cord-017772-zpf1xjqi	200	1	prolonged	prolong	VBN
cord-017772-zpf1xjqi	200	2	ICU	ICU	NNP
cord-017772-zpf1xjqi	200	3	stays	stay	VBZ
cord-017772-zpf1xjqi	200	4	Blunted	blunted	JJ
cord-017772-zpf1xjqi	200	5	rise	rise	NN
cord-017772-zpf1xjqi	200	6	in	in	IN
cord-017772-zpf1xjqi	200	7	platelet	platelet	NN
cord-017772-zpf1xjqi	200	8	count	count	NN
cord-017772-zpf1xjqi	200	9	in	in	IN
cord-017772-zpf1xjqi	200	10	critically	critically	RB
cord-017772-zpf1xjqi	200	11	ill	ill	JJ
cord-017772-zpf1xjqi	200	12	patients	patient	NNS
cord-017772-zpf1xjqi	200	13	is	be	VBZ
cord-017772-zpf1xjqi	200	14	associated	associate	VBN
cord-017772-zpf1xjqi	200	15	with	with	IN
cord-017772-zpf1xjqi	200	16	worse	bad	JJR
cord-017772-zpf1xjqi	200	17	outcome	outcome	NN
cord-017772-zpf1xjqi	200	18	The	the	DT
cord-017772-zpf1xjqi	200	19	SOFA	sofa	NN
cord-017772-zpf1xjqi	200	20	(	(	-LRB-
cord-017772-zpf1xjqi	200	21	Sepsis	sepsis	NN
cord-017772-zpf1xjqi	200	22	-	-	HYPH
cord-017772-zpf1xjqi	200	23	related	relate	VBN
cord-017772-zpf1xjqi	200	24	organ	organ	NN
cord-017772-zpf1xjqi	200	25	failure	failure	NN
cord-017772-zpf1xjqi	200	26	assessment	assessment	NN
cord-017772-zpf1xjqi	200	27	)	)	-RRB-
cord-017772-zpf1xjqi	200	28	score	score	NN
cord-017772-zpf1xjqi	200	29	to	to	TO
cord-017772-zpf1xjqi	200	30	describe	describe	VB
cord-017772-zpf1xjqi	200	31	organ	organ	NN
cord-017772-zpf1xjqi	200	32	dysfunction	dysfunction	NN
cord-017772-zpf1xjqi	200	33	/	/	SYM
cord-017772-zpf1xjqi	200	34	failure	failure	NN
cord-017772-zpf1xjqi	200	35	.	.	.
cord-017772-zpf1xjqi	201	1	On	on	IN
cord-017772-zpf1xjqi	201	2	behalf	behalf	NN
cord-017772-zpf1xjqi	201	3	of	of	IN
cord-017772-zpf1xjqi	201	4	the	the	DT
cord-017772-zpf1xjqi	201	5	working	work	VBG
cord-017772-zpf1xjqi	201	6	group	group	NN
cord-017772-zpf1xjqi	201	7	on	on	IN
cord-017772-zpf1xjqi	201	8	Sepsis	sepsis	NN
cord-017772-zpf1xjqi	201	9	-	-	HYPH
cord-017772-zpf1xjqi	201	10	related	relate	VBN
cord-017772-zpf1xjqi	201	11	problems	problem	NNS
cord-017772-zpf1xjqi	201	12	of	of	IN
cord-017772-zpf1xjqi	201	13	the	the	DT
cord-017772-zpf1xjqi	201	14	European	European	NNP
cord-017772-zpf1xjqi	201	15	Society	Society	NNP
cord-017772-zpf1xjqi	201	16	of	of	IN
cord-017772-zpf1xjqi	201	17	Intensive	Intensive	NNP
cord-017772-zpf1xjqi	201	18	Care	Care	NNP
cord-017772-zpf1xjqi	201	19	Medicine	Medicine	NNP
cord-017772-zpf1xjqi	201	20	Multiple	multiple	JJ
cord-017772-zpf1xjqi	201	21	organ	organ	NN
cord-017772-zpf1xjqi	201	22	dysfunction	dysfunction	NN
cord-017772-zpf1xjqi	201	23	score	score	NN
cord-017772-zpf1xjqi	201	24	:	:	:
cord-017772-zpf1xjqi	201	25	a	a	DT
cord-017772-zpf1xjqi	201	26	reliable	reliable	JJ
cord-017772-zpf1xjqi	201	27	descriptor	descriptor	NN
cord-017772-zpf1xjqi	201	28	of	of	IN
cord-017772-zpf1xjqi	201	29	a	a	DT
cord-017772-zpf1xjqi	201	30	complex	complex	JJ
cord-017772-zpf1xjqi	201	31	clinical	clinical	JJ
cord-017772-zpf1xjqi	201	32	outcome	outcome	NN
cord-017772-zpf1xjqi	201	33	Epidemiology	epidemiology	NN
cord-017772-zpf1xjqi	201	34	and	and	CC
cord-017772-zpf1xjqi	201	35	outcome	outcome	NN
cord-017772-zpf1xjqi	201	36	of	of	IN
cord-017772-zpf1xjqi	201	37	thrombocytopenic	thrombocytopenic	JJ
cord-017772-zpf1xjqi	201	38	patients	patient	NNS
cord-017772-zpf1xjqi	201	39	in	in	IN
cord-017772-zpf1xjqi	201	40	the	the	DT
cord-017772-zpf1xjqi	201	41	intensive	intensive	JJ
cord-017772-zpf1xjqi	201	42	care	care	NN
cord-017772-zpf1xjqi	201	43	unit	unit	NN
cord-017772-zpf1xjqi	201	44	:	:	:
cord-017772-zpf1xjqi	201	45	results	result	NNS
cord-017772-zpf1xjqi	201	46	of	of	IN
cord-017772-zpf1xjqi	201	47	a	a	DT
cord-017772-zpf1xjqi	201	48	prospective	prospective	JJ
cord-017772-zpf1xjqi	201	49	multicenter	multicenter	JJ
cord-017772-zpf1xjqi	201	50	study	study	NN
cord-017772-zpf1xjqi	201	51	Pseudothrombocytopenia	Pseudothrombocytopenia	NNP
cord-017772-zpf1xjqi	201	52	due	due	IN
cord-017772-zpf1xjqi	201	53	to	to	IN
cord-017772-zpf1xjqi	201	54	platelet	platelet	NN
cord-017772-zpf1xjqi	201	55	clumping	clumping	NN
cord-017772-zpf1xjqi	201	56	:	:	:
cord-017772-zpf1xjqi	201	57	a	a	DT
cord-017772-zpf1xjqi	201	58	case	case	NN
cord-017772-zpf1xjqi	201	59	report	report	NN
cord-017772-zpf1xjqi	201	60	and	and	CC
cord-017772-zpf1xjqi	201	61	brief	brief	JJ
cord-017772-zpf1xjqi	201	62	review	review	NN
cord-017772-zpf1xjqi	201	63	of	of	IN
cord-017772-zpf1xjqi	201	64	the	the	DT
cord-017772-zpf1xjqi	201	65	literature	literature	NN
cord-017772-zpf1xjqi	201	66	Bleeding	bleeding	NN
cord-017772-zpf1xjqi	201	67	and	and	CC
cord-017772-zpf1xjqi	201	68	coagulopathies	coagulopathie	NNS
cord-017772-zpf1xjqi	201	69	in	in	IN
cord-017772-zpf1xjqi	201	70	critical	critical	JJ
cord-017772-zpf1xjqi	201	71	care	care	NN
cord-017772-zpf1xjqi	201	72	Guidelines	guideline	NNS
cord-017772-zpf1xjqi	201	73	for	for	IN
cord-017772-zpf1xjqi	201	74	the	the	DT
cord-017772-zpf1xjqi	201	75	use	use	NN
cord-017772-zpf1xjqi	201	76	of	of	IN
cord-017772-zpf1xjqi	201	77	platelet	platelet	NN
cord-017772-zpf1xjqi	201	78	transfusions	transfusion	NNS
cord-017772-zpf1xjqi	201	79	Evidence	evidence	NN
cord-017772-zpf1xjqi	201	80	-	-	HYPH
cord-017772-zpf1xjqi	201	81	based	base	VBN
cord-017772-zpf1xjqi	201	82	platelet	platelet	NN
cord-017772-zpf1xjqi	201	83	transfusion	transfusion	NN
cord-017772-zpf1xjqi	201	84	guidelines	guideline	NNS
cord-017772-zpf1xjqi	201	85	Consensus	Consensus	NNP
cord-017772-zpf1xjqi	201	86	on	on	IN
cord-017772-zpf1xjqi	201	87	the	the	DT
cord-017772-zpf1xjqi	201	88	standardization	standardization	NN
cord-017772-zpf1xjqi	201	89	of	of	IN
cord-017772-zpf1xjqi	201	90	terminology	terminology	NN
cord-017772-zpf1xjqi	201	91	in	in	IN
cord-017772-zpf1xjqi	201	92	thrombotic	thrombotic	JJ
cord-017772-zpf1xjqi	201	93	thrombocytopenic	thrombocytopenic	JJ
cord-017772-zpf1xjqi	201	94	purpura	purpura	NN
cord-017772-zpf1xjqi	201	95	and	and	CC
cord-017772-zpf1xjqi	201	96	related	related	JJ
cord-017772-zpf1xjqi	201	97	thrombotic	thrombotic	JJ
cord-017772-zpf1xjqi	201	98	microangiopathies	microangiopathie	NNS
cord-017772-zpf1xjqi	201	99	Syndromes	Syndromes	NNPS
cord-017772-zpf1xjqi	201	100	of	of	IN
cord-017772-zpf1xjqi	201	101	thrombotic	thrombotic	JJ
cord-017772-zpf1xjqi	201	102	microangiopathy	microangiopathy	NN
cord-017772-zpf1xjqi	201	103	Thrombotic	Thrombotic	NNP
cord-017772-zpf1xjqi	201	104	thrombocytopenic	thrombocytopenic	JJ
cord-017772-zpf1xjqi	201	105	purpura	purpura	NN
cord-017772-zpf1xjqi	201	106	Thrombotic	Thrombotic	NNP
cord-017772-zpf1xjqi	201	107	thrombocytopenic	thrombocytopenic	JJ
cord-017772-zpf1xjqi	201	108	purpura	purpura	NN
cord-017772-zpf1xjqi	202	1	The	the	DT
cord-017772-zpf1xjqi	202	2	incidence	incidence	NN
cord-017772-zpf1xjqi	202	3	of	of	IN
cord-017772-zpf1xjqi	202	4	thrombotic	thrombotic	JJ
cord-017772-zpf1xjqi	202	5	thrombocytopenic	thrombocytopenic	JJ
cord-017772-zpf1xjqi	202	6	purpurahemolytic	purpurahemolytic	JJ
cord-017772-zpf1xjqi	202	7	uremic	uremic	NNP
cord-017772-zpf1xjqi	202	8	syndrome	syndrome	NN
cord-017772-zpf1xjqi	202	9	:	:	:
cord-017772-zpf1xjqi	202	10	all	all	DT
cord-017772-zpf1xjqi	202	11	patients	patient	NNS
cord-017772-zpf1xjqi	202	12	,	,	,
cord-017772-zpf1xjqi	202	13	idiopathic	idiopathic	JJ
cord-017772-zpf1xjqi	202	14	patients	patient	NNS
cord-017772-zpf1xjqi	202	15	,	,	,
cord-017772-zpf1xjqi	202	16	and	and	CC
cord-017772-zpf1xjqi	202	17	patients	patient	NNS
cord-017772-zpf1xjqi	202	18	with	with	IN
cord-017772-zpf1xjqi	202	19	severe	severe	JJ
cord-017772-zpf1xjqi	202	20	ADAMTS-13	adamts-13	ADD
cord-017772-zpf1xjqi	202	21	deficiency	deficiency	NN
cord-017772-zpf1xjqi	202	22	Epidemiology	epidemiology	NN
cord-017772-zpf1xjqi	202	23	and	and	CC
cord-017772-zpf1xjqi	202	24	pathophysiology	pathophysiology	NN
cord-017772-zpf1xjqi	202	25	of	of	IN
cord-017772-zpf1xjqi	202	26	adulthood	adulthood	NN
cord-017772-zpf1xjqi	202	27	-	-	HYPH
cord-017772-zpf1xjqi	202	28	onset	onset	NN
cord-017772-zpf1xjqi	202	29	thrombotic	thrombotic	JJ
cord-017772-zpf1xjqi	202	30	microangiopathy	microangiopathy	NN
cord-017772-zpf1xjqi	202	31	with	with	IN
cord-017772-zpf1xjqi	202	32	severe	severe	JJ
cord-017772-zpf1xjqi	202	33	ADAMTS13	ADAMTS13	NNP
cord-017772-zpf1xjqi	202	34	deficiency	deficiency	NN
cord-017772-zpf1xjqi	202	35	(	(	-LRB-
cord-017772-zpf1xjqi	202	36	thrombotic	thrombotic	JJ
cord-017772-zpf1xjqi	202	37	thrombocytopenic	thrombocytopenic	JJ
cord-017772-zpf1xjqi	202	38	purpura	purpura	NNP
cord-017772-zpf1xjqi	202	39	)	)	-RRB-
cord-017772-zpf1xjqi	202	40	:	:	:
cord-017772-zpf1xjqi	202	41	a	a	DT
cord-017772-zpf1xjqi	202	42	cross	cross	JJ
cord-017772-zpf1xjqi	202	43	-	-	JJ
cord-017772-zpf1xjqi	202	44	sectional	sectional	JJ
cord-017772-zpf1xjqi	202	45	analysis	analysis	NN
cord-017772-zpf1xjqi	202	46	of	of	IN
cord-017772-zpf1xjqi	202	47	the	the	DT
cord-017772-zpf1xjqi	202	48	French	french	JJ
cord-017772-zpf1xjqi	202	49	national	national	JJ
cord-017772-zpf1xjqi	202	50	registry	registry	NN
cord-017772-zpf1xjqi	202	51	for	for	IN
cord-017772-zpf1xjqi	202	52	thrombotic	thrombotic	JJ
cord-017772-zpf1xjqi	202	53	microangiopathy	microangiopathy	NN
cord-017772-zpf1xjqi	202	54	Thrombotic	Thrombotic	NNP
cord-017772-zpf1xjqi	202	55	thrombocytopenic	thrombocytopenic	JJ
cord-017772-zpf1xjqi	202	56	purpura	purpura	NN
cord-017772-zpf1xjqi	202	57	:	:	:
cord-017772-zpf1xjqi	202	58	diagnostic	diagnostic	JJ
cord-017772-zpf1xjqi	202	59	criteria	criterion	NNS
cord-017772-zpf1xjqi	202	60	,	,	,
cord-017772-zpf1xjqi	202	61	clinical	clinical	JJ
cord-017772-zpf1xjqi	202	62	features	feature	NNS
cord-017772-zpf1xjqi	202	63	,	,	,
cord-017772-zpf1xjqi	202	64	and	and	CC
cord-017772-zpf1xjqi	202	65	long	long	JJ
cord-017772-zpf1xjqi	202	66	-	-	HYPH
cord-017772-zpf1xjqi	202	67	term	term	NN
cord-017772-zpf1xjqi	202	68	outcomes	outcome	NNS
cord-017772-zpf1xjqi	202	69	from	from	IN
cord-017772-zpf1xjqi	202	70	1995	1995	CD
cord-017772-zpf1xjqi	202	71	through	through	IN
cord-017772-zpf1xjqi	202	72	2015	2015	CD
cord-017772-zpf1xjqi	202	73	Guidelines	Guidelines	NNPS
cord-017772-zpf1xjqi	202	74	on	on	IN
cord-017772-zpf1xjqi	202	75	the	the	DT
cord-017772-zpf1xjqi	202	76	diagnosis	diagnosis	NN
cord-017772-zpf1xjqi	202	77	and	and	CC
cord-017772-zpf1xjqi	202	78	management	management	NN
cord-017772-zpf1xjqi	202	79	of	of	IN
cord-017772-zpf1xjqi	202	80	thrombotic	thrombotic	JJ
cord-017772-zpf1xjqi	202	81	thrombocytopenic	thrombocytopenic	JJ
cord-017772-zpf1xjqi	202	82	purpura	purpura	NN
cord-017772-zpf1xjqi	202	83	and	and	CC
cord-017772-zpf1xjqi	202	84	other	other	JJ
cord-017772-zpf1xjqi	202	85	thrombotic	thrombotic	JJ
cord-017772-zpf1xjqi	202	86	microangiopathies	microangiopathie	NNS
cord-017772-zpf1xjqi	202	87	Comparison	Comparison	NNP
cord-017772-zpf1xjqi	202	88	of	of	IN
cord-017772-zpf1xjqi	202	89	plasma	plasma	NN
cord-017772-zpf1xjqi	202	90	exchange	exchange	NN
cord-017772-zpf1xjqi	202	91	with	with	IN
cord-017772-zpf1xjqi	202	92	plasma	plasma	NN
cord-017772-zpf1xjqi	202	93	infusion	infusion	NN
cord-017772-zpf1xjqi	202	94	in	in	IN
cord-017772-zpf1xjqi	202	95	the	the	DT
cord-017772-zpf1xjqi	202	96	treatment	treatment	NN
cord-017772-zpf1xjqi	202	97	of	of	IN
cord-017772-zpf1xjqi	202	98	thrombotic	thrombotic	JJ
cord-017772-zpf1xjqi	202	99	thrombocytopenic	thrombocytopenic	JJ
cord-017772-zpf1xjqi	202	100	purpura	purpura	NN
cord-017772-zpf1xjqi	202	101	.	.	.
cord-017772-zpf1xjqi	203	1	Canadian	Canadian	NNP
cord-017772-zpf1xjqi	203	2	Apheresis	Apheresis	NNP
cord-017772-zpf1xjqi	203	3	Study	Study	NNP
cord-017772-zpf1xjqi	203	4	Group	Group	NNP
cord-017772-zpf1xjqi	203	5	Towards	towards	IN
cord-017772-zpf1xjqi	203	6	definition	definition	NN
cord-017772-zpf1xjqi	203	7	,	,	,
cord-017772-zpf1xjqi	203	8	clinical	clinical	JJ
cord-017772-zpf1xjqi	203	9	and	and	CC
cord-017772-zpf1xjqi	203	10	laboratory	laboratory	NN
cord-017772-zpf1xjqi	203	11	criteria	criterion	NNS
cord-017772-zpf1xjqi	203	12	,	,	,
cord-017772-zpf1xjqi	203	13	and	and	CC
cord-017772-zpf1xjqi	203	14	a	a	DT
cord-017772-zpf1xjqi	203	15	scoring	scoring	NN
cord-017772-zpf1xjqi	203	16	system	system	NN
cord-017772-zpf1xjqi	203	17	for	for	IN
cord-017772-zpf1xjqi	204	1	disseminated	disseminate	VBN
cord-017772-zpf1xjqi	204	2	intravascular	intravascular	JJ
cord-017772-zpf1xjqi	204	3	coagulation	coagulation	NN
cord-017772-zpf1xjqi	204	4	Disseminated	disseminate	VBD
cord-017772-zpf1xjqi	204	5	intravascular	intravascular	JJ
cord-017772-zpf1xjqi	204	6	coagulation	coagulation	NN
cord-017772-zpf1xjqi	204	7	Disseminated	disseminate	VBD
cord-017772-zpf1xjqi	204	8	intravascular	intravascular	JJ
cord-017772-zpf1xjqi	204	9	coagulation	coagulation	NN
cord-017772-zpf1xjqi	204	10	Epidemiology	epidemiology	NN
cord-017772-zpf1xjqi	204	11	of	of	IN
cord-017772-zpf1xjqi	204	12	disseminated	disseminate	VBN
cord-017772-zpf1xjqi	204	13	intravascular	intravascular	JJ
cord-017772-zpf1xjqi	204	14	coagulation	coagulation	NN
cord-017772-zpf1xjqi	204	15	in	in	IN
cord-017772-zpf1xjqi	204	16	sepsis	sepsis	NN
cord-017772-zpf1xjqi	204	17	and	and	CC
cord-017772-zpf1xjqi	204	18	validation	validation	NN
cord-017772-zpf1xjqi	204	19	of	of	IN
cord-017772-zpf1xjqi	204	20	scoring	score	VBG
cord-017772-zpf1xjqi	204	21	systems	system	NNS
cord-017772-zpf1xjqi	204	22	Disseminated	disseminate	VBD
cord-017772-zpf1xjqi	204	23	intravascular	intravascular	JJ
cord-017772-zpf1xjqi	204	24	coagulation	coagulation	NN
cord-017772-zpf1xjqi	204	25	in	in	IN
cord-017772-zpf1xjqi	204	26	sepsis	sepsis	NN
cord-017772-zpf1xjqi	204	27	Trends	trend	NNS
cord-017772-zpf1xjqi	204	28	in	in	IN
cord-017772-zpf1xjqi	204	29	the	the	DT
cord-017772-zpf1xjqi	204	30	incidence	incidence	NN
cord-017772-zpf1xjqi	204	31	and	and	CC
cord-017772-zpf1xjqi	204	32	outcomes	outcome	NNS
cord-017772-zpf1xjqi	204	33	of	of	IN
cord-017772-zpf1xjqi	204	34	disseminated	disseminate	VBN
cord-017772-zpf1xjqi	204	35	intravascular	intravascular	JJ
cord-017772-zpf1xjqi	204	36	coagulation	coagulation	NN
cord-017772-zpf1xjqi	204	37	in	in	IN
cord-017772-zpf1xjqi	204	38	critically	critically	RB
cord-017772-zpf1xjqi	204	39	ill	ill	JJ
cord-017772-zpf1xjqi	204	40	patients	patient	NNS
cord-017772-zpf1xjqi	204	41	(	(	-LRB-
cord-017772-zpf1xjqi	204	42	2004	2004	CD
cord-017772-zpf1xjqi	204	43	-	-	SYM
cord-017772-zpf1xjqi	204	44	2010	2010	CD
cord-017772-zpf1xjqi	204	45	)	)	-RRB-
cord-017772-zpf1xjqi	204	46	:	:	:
cord-017772-zpf1xjqi	204	47	a	a	DT
cord-017772-zpf1xjqi	204	48	population	population	NN
cord-017772-zpf1xjqi	204	49	-	-	HYPH
cord-017772-zpf1xjqi	204	50	based	base	VBN
cord-017772-zpf1xjqi	204	51	study	study	NN
cord-017772-zpf1xjqi	205	1	The	the	DT
cord-017772-zpf1xjqi	205	2	scoring	scoring	NN
cord-017772-zpf1xjqi	205	3	system	system	NN
cord-017772-zpf1xjqi	205	4	of	of	IN
cord-017772-zpf1xjqi	205	5	the	the	DT
cord-017772-zpf1xjqi	205	6	scientific	scientific	JJ
cord-017772-zpf1xjqi	205	7	and	and	CC
cord-017772-zpf1xjqi	205	8	standardisation	standardisation	NN
cord-017772-zpf1xjqi	205	9	committee	committee	NN
cord-017772-zpf1xjqi	205	10	on	on	IN
cord-017772-zpf1xjqi	205	11	disseminated	disseminate	VBN
cord-017772-zpf1xjqi	205	12	intravascular	intravascular	JJ
cord-017772-zpf1xjqi	205	13	coagulation	coagulation	NN
cord-017772-zpf1xjqi	205	14	of	of	IN
cord-017772-zpf1xjqi	205	15	the	the	DT
cord-017772-zpf1xjqi	205	16	International	International	NNP
cord-017772-zpf1xjqi	205	17	Society	Society	NNP
cord-017772-zpf1xjqi	205	18	on	on	IN
cord-017772-zpf1xjqi	205	19	Thrombosis	Thrombosis	NNP
cord-017772-zpf1xjqi	205	20	and	and	CC
cord-017772-zpf1xjqi	205	21	Haemostasis	Haemostasis	NNP
cord-017772-zpf1xjqi	205	22	:	:	:
cord-017772-zpf1xjqi	205	23	a	a	DT
cord-017772-zpf1xjqi	205	24	5-year	5-year	CD
cord-017772-zpf1xjqi	205	25	overview	overview	NN
cord-017772-zpf1xjqi	205	26	Thrombocytopenia	Thrombocytopenia	NNP
cord-017772-zpf1xjqi	205	27	in	in	IN
cord-017772-zpf1xjqi	205	28	the	the	DT
cord-017772-zpf1xjqi	205	29	ICU	ICU	NNP
cord-017772-zpf1xjqi	205	30	:	:	:
cord-017772-zpf1xjqi	205	31	disseminated	disseminate	VBN
cord-017772-zpf1xjqi	205	32	intravascular	intravascular	JJ
cord-017772-zpf1xjqi	205	33	coagulation	coagulation	NN
cord-017772-zpf1xjqi	205	34	and	and	CC
cord-017772-zpf1xjqi	205	35	thrombotic	thrombotic	JJ
cord-017772-zpf1xjqi	205	36	microangiopathies	microangiopathie	NNS
cord-017772-zpf1xjqi	205	37	-	-	:
cord-017772-zpf1xjqi	205	38	what	what	WP
cord-017772-zpf1xjqi	205	39	intensivists	intensivist	NNS
cord-017772-zpf1xjqi	205	40	need	need	VBP
cord-017772-zpf1xjqi	205	41	to	to	TO
cord-017772-zpf1xjqi	205	42	know	know	VB
cord-017772-zpf1xjqi	205	43	Prospective	prospective	JJ
cord-017772-zpf1xjqi	205	44	validation	validation	NN
cord-017772-zpf1xjqi	205	45	of	of	IN
cord-017772-zpf1xjqi	205	46	the	the	DT
cord-017772-zpf1xjqi	205	47	International	International	NNP
cord-017772-zpf1xjqi	205	48	Society	Society	NNP
cord-017772-zpf1xjqi	205	49	of	of	IN
cord-017772-zpf1xjqi	205	50	Thrombosis	Thrombosis	NNP
cord-017772-zpf1xjqi	205	51	and	and	CC
cord-017772-zpf1xjqi	205	52	Haemostasis	Haemostasis	NNP
cord-017772-zpf1xjqi	205	53	scoring	score	VBG
cord-017772-zpf1xjqi	205	54	system	system	NN
cord-017772-zpf1xjqi	205	55	for	for	IN
cord-017772-zpf1xjqi	205	56	disseminated	disseminate	VBN
cord-017772-zpf1xjqi	205	57	intravascular	intravascular	JJ
cord-017772-zpf1xjqi	205	58	coagulation	coagulation	NN
cord-017772-zpf1xjqi	206	1	What	what	WP
cord-017772-zpf1xjqi	206	2	's	be	VBZ
cord-017772-zpf1xjqi	206	3	new	new	JJ
cord-017772-zpf1xjqi	206	4	in	in	IN
cord-017772-zpf1xjqi	206	5	the	the	DT
cord-017772-zpf1xjqi	206	6	diagnostic	diagnostic	JJ
cord-017772-zpf1xjqi	206	7	criteria	criterion	NNS
cord-017772-zpf1xjqi	206	8	of	of	IN
cord-017772-zpf1xjqi	206	9	disseminated	disseminate	VBN
cord-017772-zpf1xjqi	206	10	intravascular	intravascular	JJ
cord-017772-zpf1xjqi	206	11	coagulation	coagulation	NN
cord-017772-zpf1xjqi	206	12	?	?	.
cord-017772-zpf1xjqi	207	1	Diagnosis	diagnosis	NN
cord-017772-zpf1xjqi	207	2	and	and	CC
cord-017772-zpf1xjqi	207	3	treatment	treatment	NN
cord-017772-zpf1xjqi	207	4	of	of	IN
cord-017772-zpf1xjqi	207	5	disseminated	disseminate	VBN
cord-017772-zpf1xjqi	207	6	intravascular	intravascular	JJ
cord-017772-zpf1xjqi	207	7	coagulation	coagulation	NN
cord-017772-zpf1xjqi	207	8	(	(	-LRB-
cord-017772-zpf1xjqi	207	9	DIC	DIC	NNP
cord-017772-zpf1xjqi	207	10	)	)	-RRB-
cord-017772-zpf1xjqi	207	11	according	accord	VBG
cord-017772-zpf1xjqi	207	12	to	to	IN
cord-017772-zpf1xjqi	207	13	four	four	CD
cord-017772-zpf1xjqi	207	14	DIC	DIC	NNP
cord-017772-zpf1xjqi	207	15	guidelines	guideline	NNS
cord-017772-zpf1xjqi	207	16	Efficacy	Efficacy	NNP
cord-017772-zpf1xjqi	207	17	and	and	CC
cord-017772-zpf1xjqi	207	18	safety	safety	NN
cord-017772-zpf1xjqi	207	19	of	of	IN
cord-017772-zpf1xjqi	207	20	tifacogin	tifacogin	NNP
cord-017772-zpf1xjqi	207	21	(	(	-LRB-
cord-017772-zpf1xjqi	207	22	recombinant	recombinant	JJ
cord-017772-zpf1xjqi	207	23	tissue	tissue	NN
cord-017772-zpf1xjqi	207	24	factor	factor	NN
cord-017772-zpf1xjqi	207	25	pathway	pathway	NN
cord-017772-zpf1xjqi	207	26	inhibitor	inhibitor	NN
cord-017772-zpf1xjqi	207	27	)	)	-RRB-
cord-017772-zpf1xjqi	207	28	in	in	IN
cord-017772-zpf1xjqi	207	29	severe	severe	JJ
cord-017772-zpf1xjqi	207	30	sepsis	sepsis	NN
cord-017772-zpf1xjqi	207	31	:	:	:
cord-017772-zpf1xjqi	207	32	a	a	DT
cord-017772-zpf1xjqi	207	33	randomized	randomized	JJ
cord-017772-zpf1xjqi	207	34	controlled	control	VBN
cord-017772-zpf1xjqi	207	35	trial	trial	NN
cord-017772-zpf1xjqi	207	36	Caring	care	VBG
cord-017772-zpf1xjqi	207	37	for	for	IN
cord-017772-zpf1xjqi	207	38	the	the	DT
cord-017772-zpf1xjqi	207	39	critically	critically	RB
cord-017772-zpf1xjqi	207	40	ill	ill	JJ
cord-017772-zpf1xjqi	207	41	patient	patient	NN
cord-017772-zpf1xjqi	207	42	.	.	.
cord-017772-zpf1xjqi	208	1	High	high	JJ
cord-017772-zpf1xjqi	208	2	-	-	HYPH
cord-017772-zpf1xjqi	208	3	dose	dose	NN
cord-017772-zpf1xjqi	208	4	antithrombin	antithrombin	NN
cord-017772-zpf1xjqi	208	5	III	III	NNP
cord-017772-zpf1xjqi	208	6	in	in	IN
cord-017772-zpf1xjqi	208	7	severe	severe	JJ
cord-017772-zpf1xjqi	208	8	sepsis	sepsis	NN
cord-017772-zpf1xjqi	208	9	:	:	:
cord-017772-zpf1xjqi	208	10	a	a	DT
cord-017772-zpf1xjqi	208	11	randomized	randomized	JJ
cord-017772-zpf1xjqi	208	12	controlled	control	VBN
cord-017772-zpf1xjqi	208	13	trial	trial	NN
cord-017772-zpf1xjqi	208	14	Efficacy	Efficacy	NNP
cord-017772-zpf1xjqi	208	15	and	and	CC
cord-017772-zpf1xjqi	208	16	safety	safety	NN
cord-017772-zpf1xjqi	208	17	of	of	IN
cord-017772-zpf1xjqi	208	18	recombinant	recombinant	JJ
cord-017772-zpf1xjqi	208	19	human	human	NN
cord-017772-zpf1xjqi	208	20	activated	activate	VBN
cord-017772-zpf1xjqi	208	21	protein	protein	NN
cord-017772-zpf1xjqi	208	22	C	c	NN
cord-017772-zpf1xjqi	208	23	for	for	IN
cord-017772-zpf1xjqi	208	24	severe	severe	JJ
cord-017772-zpf1xjqi	208	25	sepsis	sepsis	NN
cord-017772-zpf1xjqi	208	26	Treatment	treatment	NN
cord-017772-zpf1xjqi	208	27	effects	effect	NNS
cord-017772-zpf1xjqi	208	28	of	of	IN
cord-017772-zpf1xjqi	208	29	drotrecogin	drotrecogin	NNP
cord-017772-zpf1xjqi	208	30	alfa	alfa	NNP
cord-017772-zpf1xjqi	208	31	(	(	-LRB-
cord-017772-zpf1xjqi	208	32	activated	activate	VBN
cord-017772-zpf1xjqi	208	33	)	)	-RRB-
cord-017772-zpf1xjqi	208	34	in	in	IN
cord-017772-zpf1xjqi	208	35	patients	patient	NNS
cord-017772-zpf1xjqi	208	36	with	with	IN
cord-017772-zpf1xjqi	208	37	severe	severe	JJ
cord-017772-zpf1xjqi	208	38	sepsis	sepsis	NN
cord-017772-zpf1xjqi	208	39	with	with	IN
cord-017772-zpf1xjqi	208	40	or	or	CC
cord-017772-zpf1xjqi	208	41	without	without	IN
cord-017772-zpf1xjqi	208	42	overt	overt	JJ
cord-017772-zpf1xjqi	208	43	disseminated	disseminate	VBN
cord-017772-zpf1xjqi	208	44	intravascular	intravascular	JJ
cord-017772-zpf1xjqi	208	45	coagulation	coagulation	NN
cord-017772-zpf1xjqi	208	46	Drotrecogin	Drotrecogin	NNP
cord-017772-zpf1xjqi	208	47	alfa	alfa	NNP
cord-017772-zpf1xjqi	208	48	(	(	-LRB-
cord-017772-zpf1xjqi	208	49	activated	activate	VBN
cord-017772-zpf1xjqi	208	50	)	)	-RRB-
cord-017772-zpf1xjqi	208	51	in	in	IN
cord-017772-zpf1xjqi	208	52	adults	adult	NNS
cord-017772-zpf1xjqi	208	53	with	with	IN
cord-017772-zpf1xjqi	208	54	septic	septic	JJ
cord-017772-zpf1xjqi	208	55	shock	shock	NN
cord-017772-zpf1xjqi	209	1	Identifying	identify	VBG
cord-017772-zpf1xjqi	209	2	drugs	drug	NNS
cord-017772-zpf1xjqi	209	3	that	that	WDT
cord-017772-zpf1xjqi	209	4	cause	cause	VBP
cord-017772-zpf1xjqi	209	5	acute	acute	JJ
cord-017772-zpf1xjqi	209	6	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	209	7	:	:	:
cord-017772-zpf1xjqi	209	8	an	an	DT
cord-017772-zpf1xjqi	209	9	analysis	analysis	NN
cord-017772-zpf1xjqi	209	10	using	use	VBG
cord-017772-zpf1xjqi	209	11	3	3	CD
cord-017772-zpf1xjqi	209	12	distinct	distinct	JJ
cord-017772-zpf1xjqi	209	13	methods	method	NNS
cord-017772-zpf1xjqi	209	14	How	how	WRB
cord-017772-zpf1xjqi	209	15	I	-PRON-	PRP
cord-017772-zpf1xjqi	209	16	evaluate	evaluate	VBP
cord-017772-zpf1xjqi	209	17	and	and	CC
cord-017772-zpf1xjqi	209	18	treat	treat	VBP
cord-017772-zpf1xjqi	209	19	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	209	20	in	in	IN
cord-017772-zpf1xjqi	209	21	the	the	DT
cord-017772-zpf1xjqi	209	22	intensive	intensive	JJ
cord-017772-zpf1xjqi	209	23	care	care	NN
cord-017772-zpf1xjqi	209	24	unit	unit	NN
cord-017772-zpf1xjqi	209	25	patient	patient	NN
cord-017772-zpf1xjqi	209	26	Drug	drug	NN
cord-017772-zpf1xjqi	209	27	-	-	HYPH
cord-017772-zpf1xjqi	209	28	induced	induce	VBN
cord-017772-zpf1xjqi	209	29	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	209	30	in	in	IN
cord-017772-zpf1xjqi	209	31	critically	critically	RB
cord-017772-zpf1xjqi	209	32	ill	ill	JJ
cord-017772-zpf1xjqi	209	33	patients	patient	NNS
cord-017772-zpf1xjqi	209	34	Drug	drug	NN
cord-017772-zpf1xjqi	209	35	-	-	HYPH
cord-017772-zpf1xjqi	209	36	induced	induce	VBN
cord-017772-zpf1xjqi	209	37	immune	immune	JJ
cord-017772-zpf1xjqi	209	38	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	209	39	Drug	drug	NN
cord-017772-zpf1xjqi	209	40	-	-	HYPH
cord-017772-zpf1xjqi	209	41	induced	induce	VBN
cord-017772-zpf1xjqi	209	42	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	209	43	:	:	:
cord-017772-zpf1xjqi	209	44	2019	2019	CD
cord-017772-zpf1xjqi	209	45	update	update	NN
cord-017772-zpf1xjqi	209	46	of	of	IN
cord-017772-zpf1xjqi	209	47	clinical	clinical	JJ
cord-017772-zpf1xjqi	209	48	and	and	CC
cord-017772-zpf1xjqi	209	49	laboratory	laboratory	NN
cord-017772-zpf1xjqi	209	50	data	datum	NNS
cord-017772-zpf1xjqi	209	51	Heparin	Heparin	NNP
cord-017772-zpf1xjqi	209	52	-	-	HYPH
cord-017772-zpf1xjqi	209	53	Induced	induce	VBN
cord-017772-zpf1xjqi	209	54	Thrombocytopenia	Thrombocytopenia	NNP
cord-017772-zpf1xjqi	209	55	Heparininduced	Heparininduced	NNP
cord-017772-zpf1xjqi	209	56	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	209	57	in	in	IN
cord-017772-zpf1xjqi	209	58	the	the	DT
cord-017772-zpf1xjqi	209	59	critically	critically	RB
cord-017772-zpf1xjqi	209	60	ill	ill	JJ
cord-017772-zpf1xjqi	209	61	patient	patient	NN
cord-017772-zpf1xjqi	209	62	Treatment	treatment	NN
cord-017772-zpf1xjqi	209	63	and	and	CC
cord-017772-zpf1xjqi	209	64	prevention	prevention	NN
cord-017772-zpf1xjqi	209	65	of	of	IN
cord-017772-zpf1xjqi	209	66	heparin	heparin	NN
cord-017772-zpf1xjqi	209	67	-	-	HYPH
cord-017772-zpf1xjqi	209	68	induced	induce	VBN
cord-017772-zpf1xjqi	209	69	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	209	70	:	:	:
cord-017772-zpf1xjqi	209	71	Antithrombotic	Antithrombotic	NNP
cord-017772-zpf1xjqi	209	72	Therapy	Therapy	NNP
cord-017772-zpf1xjqi	209	73	and	and	CC
cord-017772-zpf1xjqi	209	74	Prevention	Prevention	NNP
cord-017772-zpf1xjqi	209	75	of	of	IN
cord-017772-zpf1xjqi	209	76	Thrombosis	Thrombosis	NNP
cord-017772-zpf1xjqi	209	77	,	,	,
cord-017772-zpf1xjqi	210	1	9th	9th	JJ
cord-017772-zpf1xjqi	210	2	ed	ed	NNP
cord-017772-zpf1xjqi	210	3	:	:	:
cord-017772-zpf1xjqi	210	4	American	American	NNP
cord-017772-zpf1xjqi	210	5	College	College	NNP
cord-017772-zpf1xjqi	210	6	of	of	IN
cord-017772-zpf1xjqi	210	7	Chest	Chest	NNP
cord-017772-zpf1xjqi	210	8	Physicians	Physicians	NNP
cord-017772-zpf1xjqi	210	9	Evidence	Evidence	NNP
cord-017772-zpf1xjqi	210	10	-	-	HYPH
cord-017772-zpf1xjqi	210	11	Based	Based	NNP
cord-017772-zpf1xjqi	210	12	Clinical	Clinical	NNP
cord-017772-zpf1xjqi	210	13	Practice	Practice	NNP
cord-017772-zpf1xjqi	210	14	Guidelines	Guidelines	NNPS
cord-017772-zpf1xjqi	210	15	Temporal	temporal	JJ
cord-017772-zpf1xjqi	210	16	aspects	aspect	NNS
cord-017772-zpf1xjqi	210	17	of	of	IN
cord-017772-zpf1xjqi	210	18	heparin	heparin	NN
cord-017772-zpf1xjqi	210	19	-	-	HYPH
cord-017772-zpf1xjqi	210	20	induced	induce	VBN
cord-017772-zpf1xjqi	210	21	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	210	22	Impact	impact	NN
cord-017772-zpf1xjqi	210	23	of	of	IN
cord-017772-zpf1xjqi	210	24	the	the	DT
cord-017772-zpf1xjqi	210	25	patient	patient	JJ
cord-017772-zpf1xjqi	210	26	population	population	NN
cord-017772-zpf1xjqi	210	27	on	on	IN
cord-017772-zpf1xjqi	210	28	the	the	DT
cord-017772-zpf1xjqi	210	29	risk	risk	NN
cord-017772-zpf1xjqi	210	30	for	for	IN
cord-017772-zpf1xjqi	210	31	heparininduced	heparininduced	JJ
cord-017772-zpf1xjqi	210	32	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	210	33	Argatroban	Argatroban	NNP
cord-017772-zpf1xjqi	210	34	in	in	IN
cord-017772-zpf1xjqi	210	35	the	the	DT
cord-017772-zpf1xjqi	210	36	management	management	NN
cord-017772-zpf1xjqi	210	37	of	of	IN
cord-017772-zpf1xjqi	210	38	heparin	heparin	NN
cord-017772-zpf1xjqi	210	39	-	-	HYPH
cord-017772-zpf1xjqi	210	40	induced	induce	VBN
cord-017772-zpf1xjqi	210	41	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	210	42	:	:	:
cord-017772-zpf1xjqi	210	43	a	a	DT
cord-017772-zpf1xjqi	210	44	multicenter	multicenter	JJ
cord-017772-zpf1xjqi	210	45	clinical	clinical	JJ
cord-017772-zpf1xjqi	210	46	trial	trial	NN
cord-017772-zpf1xjqi	210	47	Evaluation	Evaluation	NNP
cord-017772-zpf1xjqi	210	48	of	of	IN
cord-017772-zpf1xjqi	210	49	pretest	pretest	NN
cord-017772-zpf1xjqi	210	50	clinical	clinical	JJ
cord-017772-zpf1xjqi	210	51	score	score	NN
cord-017772-zpf1xjqi	210	52	(	(	-LRB-
cord-017772-zpf1xjqi	210	53	4	4	CD
cord-017772-zpf1xjqi	210	54	T	T	NNP
cord-017772-zpf1xjqi	210	55	's	's	POS
cord-017772-zpf1xjqi	210	56	)	)	-RRB-
cord-017772-zpf1xjqi	210	57	for	for	IN
cord-017772-zpf1xjqi	210	58	the	the	DT
cord-017772-zpf1xjqi	210	59	diagnosis	diagnosis	NN
cord-017772-zpf1xjqi	210	60	of	of	IN
cord-017772-zpf1xjqi	210	61	heparin	heparin	NN
cord-017772-zpf1xjqi	210	62	-	-	HYPH
cord-017772-zpf1xjqi	210	63	induced	induce	VBN
cord-017772-zpf1xjqi	210	64	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	210	65	in	in	IN
cord-017772-zpf1xjqi	210	66	two	two	CD
cord-017772-zpf1xjqi	210	67	clinical	clinical	JJ
cord-017772-zpf1xjqi	210	68	settings	setting	NNS
cord-017772-zpf1xjqi	211	1	Predictive	predictive	JJ
cord-017772-zpf1xjqi	211	2	value	value	NN
cord-017772-zpf1xjqi	211	3	of	of	IN
cord-017772-zpf1xjqi	211	4	the	the	DT
cord-017772-zpf1xjqi	211	5	4Ts	4ts	JJ
cord-017772-zpf1xjqi	211	6	scoring	scoring	NN
cord-017772-zpf1xjqi	211	7	system	system	NN
cord-017772-zpf1xjqi	211	8	for	for	IN
cord-017772-zpf1xjqi	211	9	heparin	heparin	NN
cord-017772-zpf1xjqi	211	10	-	-	HYPH
cord-017772-zpf1xjqi	211	11	induced	induce	VBN
cord-017772-zpf1xjqi	211	12	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	211	13	:	:	:
cord-017772-zpf1xjqi	211	14	a	a	DT
cord-017772-zpf1xjqi	211	15	systematic	systematic	JJ
cord-017772-zpf1xjqi	211	16	review	review	NN
cord-017772-zpf1xjqi	211	17	and	and	CC
cord-017772-zpf1xjqi	211	18	meta	meta	NNP
cord-017772-zpf1xjqi	211	19	-	-	HYPH
cord-017772-zpf1xjqi	211	20	analysis	analysis	NN
cord-017772-zpf1xjqi	211	21	Evaluating	evaluate	VBG
cord-017772-zpf1xjqi	211	22	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	211	23	during	during	IN
cord-017772-zpf1xjqi	211	24	heparin	heparin	NN
cord-017772-zpf1xjqi	211	25	therapy	therapy	NN
cord-017772-zpf1xjqi	212	1	A	a	DT
cord-017772-zpf1xjqi	212	2	prospective	prospective	JJ
cord-017772-zpf1xjqi	212	3	,	,	,
cord-017772-zpf1xjqi	212	4	observational	observational	JJ
cord-017772-zpf1xjqi	212	5	registry	registry	NN
cord-017772-zpf1xjqi	212	6	of	of	IN
cord-017772-zpf1xjqi	212	7	patients	patient	NNS
cord-017772-zpf1xjqi	212	8	with	with	IN
cord-017772-zpf1xjqi	212	9	severe	severe	JJ
cord-017772-zpf1xjqi	212	10	sepsis	sepsis	NN
cord-017772-zpf1xjqi	213	1	:	:	:
cord-017772-zpf1xjqi	213	2	the	the	DT
cord-017772-zpf1xjqi	213	3	Canadian	Canadian	NNP
cord-017772-zpf1xjqi	213	4	Sepsis	Sepsis	NNP
cord-017772-zpf1xjqi	213	5	Treatment	Treatment	NNP
cord-017772-zpf1xjqi	213	6	and	and	CC
cord-017772-zpf1xjqi	213	7	Response	Response	NNP
cord-017772-zpf1xjqi	213	8	Registry	Registry	NNP
cord-017772-zpf1xjqi	213	9	Thrombocytopenia	Thrombocytopenia	NNP
cord-017772-zpf1xjqi	213	10	is	be	VBZ
cord-017772-zpf1xjqi	213	11	associated	associate	VBN
cord-017772-zpf1xjqi	213	12	with	with	IN
cord-017772-zpf1xjqi	213	13	a	a	DT
cord-017772-zpf1xjqi	213	14	dysregulated	dysregulate	VBN
cord-017772-zpf1xjqi	213	15	host	host	NN
cord-017772-zpf1xjqi	213	16	response	response	NN
cord-017772-zpf1xjqi	213	17	in	in	IN
cord-017772-zpf1xjqi	213	18	critically	critically	RB
cord-017772-zpf1xjqi	213	19	ill	ill	JJ
cord-017772-zpf1xjqi	213	20	sepsis	sepsis	NN
cord-017772-zpf1xjqi	213	21	patients	patient	NNS
cord-017772-zpf1xjqi	213	22	Is	be	VBZ
cord-017772-zpf1xjqi	213	23	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	213	24	an	an	DT
cord-017772-zpf1xjqi	213	25	early	early	JJ
cord-017772-zpf1xjqi	213	26	prognostic	prognostic	JJ
cord-017772-zpf1xjqi	213	27	marker	marker	NN
cord-017772-zpf1xjqi	213	28	in	in	IN
cord-017772-zpf1xjqi	213	29	septic	septic	JJ
cord-017772-zpf1xjqi	213	30	shock	shock	NN
cord-017772-zpf1xjqi	213	31	?	?	.
cord-017772-zpf1xjqi	214	1	Sepsisassociated	sepsisassociated	JJ
cord-017772-zpf1xjqi	214	2	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	215	1	Surviving	survive	VBG
cord-017772-zpf1xjqi	215	2	Sepsis	Sepsis	NNP
cord-017772-zpf1xjqi	215	3	campaign	campaign	NN
cord-017772-zpf1xjqi	215	4	:	:	:
cord-017772-zpf1xjqi	215	5	international	international	JJ
cord-017772-zpf1xjqi	215	6	guidelines	guideline	NNS
cord-017772-zpf1xjqi	215	7	for	for	IN
cord-017772-zpf1xjqi	215	8	Management	Management	NNP
cord-017772-zpf1xjqi	215	9	of	of	IN
cord-017772-zpf1xjqi	215	10	Sepsis	Sepsis	NNP
cord-017772-zpf1xjqi	215	11	and	and	CC
cord-017772-zpf1xjqi	215	12	Septic	Septic	NNP
cord-017772-zpf1xjqi	215	13	Shock	shock	NN
cord-017772-zpf1xjqi	215	14	:	:	:
cord-017772-zpf1xjqi	216	1	2016	2016	CD
cord-017772-zpf1xjqi	216	2	Complications	complication	NNS
cord-017772-zpf1xjqi	216	3	of	of	IN
cord-017772-zpf1xjqi	216	4	massive	massive	JJ
cord-017772-zpf1xjqi	216	5	transfusion	transfusion	NN
cord-017772-zpf1xjqi	216	6	Damage	damage	NN
cord-017772-zpf1xjqi	216	7	control	control	NN
cord-017772-zpf1xjqi	216	8	resuscitation	resuscitation	NN
cord-017772-zpf1xjqi	216	9	Thrombocytopenia	Thrombocytopenia	NNP
cord-017772-zpf1xjqi	216	10	and	and	CC
cord-017772-zpf1xjqi	216	11	extracorporeal	extracorporeal	JJ
cord-017772-zpf1xjqi	216	12	membrane	membrane	NN
cord-017772-zpf1xjqi	216	13	oxygenation	oxygenation	NN
cord-017772-zpf1xjqi	216	14	in	in	IN
cord-017772-zpf1xjqi	216	15	adults	adult	NNS
cord-017772-zpf1xjqi	216	16	with	with	IN
cord-017772-zpf1xjqi	216	17	acute	acute	JJ
cord-017772-zpf1xjqi	216	18	respiratory	respiratory	JJ
cord-017772-zpf1xjqi	216	19	failure	failure	NN
cord-017772-zpf1xjqi	216	20	:	:	:
cord-017772-zpf1xjqi	217	1	a	a	DT
cord-017772-zpf1xjqi	217	2	cohort	cohort	NN
cord-017772-zpf1xjqi	217	3	study	study	NN
cord-017772-zpf1xjqi	217	4	Extracorporeal	extracorporeal	JJ
cord-017772-zpf1xjqi	217	5	membrane	membrane	NN
cord-017772-zpf1xjqi	217	6	oxygenation	oxygenation	NN
cord-017772-zpf1xjqi	217	7	for	for	IN
cord-017772-zpf1xjqi	217	8	severe	severe	JJ
cord-017772-zpf1xjqi	217	9	acute	acute	JJ
cord-017772-zpf1xjqi	217	10	respiratory	respiratory	JJ
cord-017772-zpf1xjqi	217	11	distress	distress	NN
cord-017772-zpf1xjqi	217	12	syndrome	syndrome	NN
cord-017772-zpf1xjqi	217	13	Thrombocytopenia	Thrombocytopenia	NNP
cord-017772-zpf1xjqi	217	14	in	in	IN
cord-017772-zpf1xjqi	217	15	patients	patient	NNS
cord-017772-zpf1xjqi	217	16	treated	treat	VBN
cord-017772-zpf1xjqi	217	17	with	with	IN
cord-017772-zpf1xjqi	217	18	heparin	heparin	NN
cord-017772-zpf1xjqi	217	19	,	,	,
cord-017772-zpf1xjqi	217	20	combination	combination	NN
cord-017772-zpf1xjqi	217	21	antiplatelet	antiplatelet	NN
cord-017772-zpf1xjqi	217	22	therapy	therapy	NN
cord-017772-zpf1xjqi	217	23	,	,	,
cord-017772-zpf1xjqi	217	24	and	and	CC
cord-017772-zpf1xjqi	217	25	intra	intra	JJ
cord-017772-zpf1xjqi	217	26	-	-	JJ
cord-017772-zpf1xjqi	217	27	aortic	aortic	JJ
cord-017772-zpf1xjqi	217	28	balloon	balloon	NN
cord-017772-zpf1xjqi	217	29	pump	pump	NN
cord-017772-zpf1xjqi	217	30	counterpulsation	counterpulsation	NN
cord-017772-zpf1xjqi	217	31	Clinical	clinical	JJ
cord-017772-zpf1xjqi	217	32	implications	implication	NNS
cord-017772-zpf1xjqi	217	33	of	of	IN
cord-017772-zpf1xjqi	217	34	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	217	35	among	among	IN
cord-017772-zpf1xjqi	217	36	patients	patient	NNS
cord-017772-zpf1xjqi	217	37	undergoing	undergo	VBG
cord-017772-zpf1xjqi	217	38	intra	intra	JJ
cord-017772-zpf1xjqi	217	39	-	-	JJ
cord-017772-zpf1xjqi	217	40	aortic	aortic	JJ
cord-017772-zpf1xjqi	217	41	balloon	balloon	NN
cord-017772-zpf1xjqi	217	42	pump	pump	NN
cord-017772-zpf1xjqi	217	43	counterpulsation	counterpulsation	NN
cord-017772-zpf1xjqi	217	44	in	in	IN
cord-017772-zpf1xjqi	217	45	the	the	DT
cord-017772-zpf1xjqi	217	46	coronary	coronary	JJ
cord-017772-zpf1xjqi	217	47	care	care	NN
cord-017772-zpf1xjqi	217	48	unit	unit	NN
cord-017772-zpf1xjqi	217	49	Platelet	platelet	NN
cord-017772-zpf1xjqi	217	50	transfusions	transfusion	NNS
cord-017772-zpf1xjqi	217	51	for	for	IN
cord-017772-zpf1xjqi	217	52	critically	critically	RB
cord-017772-zpf1xjqi	217	53	ill	ill	JJ
cord-017772-zpf1xjqi	217	54	patients	patient	NNS
cord-017772-zpf1xjqi	217	55	with	with	IN
cord-017772-zpf1xjqi	217	56	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	218	1	The	the	DT
cord-017772-zpf1xjqi	218	2	threshold	threshold	NN
cord-017772-zpf1xjqi	218	3	for	for	IN
cord-017772-zpf1xjqi	218	4	prophylactic	prophylactic	JJ
cord-017772-zpf1xjqi	218	5	platelet	platelet	NN
cord-017772-zpf1xjqi	218	6	transfusions	transfusion	NNS
cord-017772-zpf1xjqi	218	7	in	in	IN
cord-017772-zpf1xjqi	218	8	adults	adult	NNS
cord-017772-zpf1xjqi	218	9	with	with	IN
cord-017772-zpf1xjqi	218	10	acute	acute	JJ
cord-017772-zpf1xjqi	218	11	myeloid	myeloid	NN
cord-017772-zpf1xjqi	218	12	leukemia	leukemia	NN
cord-017772-zpf1xjqi	218	13	Gruppo	Gruppo	NNP
cord-017772-zpf1xjqi	218	14	Italiano	Italiano	NNP
cord-017772-zpf1xjqi	219	1	Malattie	Malattie	NNP
cord-017772-zpf1xjqi	219	2	Ematologiche	Ematologiche	NNP
cord-017772-zpf1xjqi	219	3	Maligne	Maligne	NNP
cord-017772-zpf1xjqi	220	1	dell'Adulto	dell'Adulto	NNP
cord-017772-zpf1xjqi	220	2	Comparison	comparison	NN
cord-017772-zpf1xjqi	220	3	of	of	IN
cord-017772-zpf1xjqi	220	4	different	different	JJ
cord-017772-zpf1xjqi	220	5	platelet	platelet	NN
cord-017772-zpf1xjqi	220	6	count	count	NN
cord-017772-zpf1xjqi	220	7	thresholds	threshold	NNS
cord-017772-zpf1xjqi	220	8	to	to	TO
cord-017772-zpf1xjqi	220	9	guide	guide	VB
cord-017772-zpf1xjqi	220	10	administration	administration	NN
cord-017772-zpf1xjqi	220	11	of	of	IN
cord-017772-zpf1xjqi	220	12	prophylactic	prophylactic	JJ
cord-017772-zpf1xjqi	220	13	platelet	platelet	NN
cord-017772-zpf1xjqi	220	14	transfusion	transfusion	NN
cord-017772-zpf1xjqi	220	15	for	for	IN
cord-017772-zpf1xjqi	220	16	preventing	prevent	VBG
cord-017772-zpf1xjqi	220	17	bleeding	bleed	VBG
cord-017772-zpf1xjqi	220	18	in	in	IN
cord-017772-zpf1xjqi	220	19	people	people	NNS
cord-017772-zpf1xjqi	220	20	with	with	IN
cord-017772-zpf1xjqi	220	21	haematological	haematological	JJ
cord-017772-zpf1xjqi	220	22	disorders	disorder	NNS
cord-017772-zpf1xjqi	220	23	after	after	IN
cord-017772-zpf1xjqi	220	24	myelosuppressive	myelosuppressive	NNP
cord-017772-zpf1xjqi	220	25	chemotherapy	chemotherapy	NN
cord-017772-zpf1xjqi	220	26	or	or	CC
cord-017772-zpf1xjqi	220	27	stem	stem	NN
cord-017772-zpf1xjqi	220	28	cell	cell	NN
cord-017772-zpf1xjqi	220	29	transplantation	transplantation	NN
cord-017772-zpf1xjqi	220	30	Platelet	platelet	NN
cord-017772-zpf1xjqi	220	31	transfusion	transfusion	NN
cord-017772-zpf1xjqi	220	32	for	for	IN
cord-017772-zpf1xjqi	220	33	patients	patient	NNS
cord-017772-zpf1xjqi	220	34	with	with	IN
cord-017772-zpf1xjqi	220	35	Cancer	cancer	NN
cord-017772-zpf1xjqi	220	36	:	:	:
cord-017772-zpf1xjqi	220	37	American	American	NNP
cord-017772-zpf1xjqi	220	38	Society	Society	NNP
cord-017772-zpf1xjqi	220	39	of	of	IN
cord-017772-zpf1xjqi	220	40	Clinical	Clinical	NNP
cord-017772-zpf1xjqi	220	41	Oncology	Oncology	NNP
cord-017772-zpf1xjqi	220	42	Clinical	Clinical	NNP
cord-017772-zpf1xjqi	220	43	Practice	Practice	NNP
cord-017772-zpf1xjqi	220	44	Guideline	Guideline	NNP
cord-017772-zpf1xjqi	221	1	Update	update	VB
cord-017772-zpf1xjqi	221	2	Fresh	fresh	JJ
cord-017772-zpf1xjqi	221	3	frozen	frozen	JJ
cord-017772-zpf1xjqi	221	4	plasma	plasma	NN
cord-017772-zpf1xjqi	221	5	and	and	CC
cord-017772-zpf1xjqi	221	6	platelet	platelet	NN
cord-017772-zpf1xjqi	221	7	transfusion	transfusion	NN
cord-017772-zpf1xjqi	221	8	for	for	IN
cord-017772-zpf1xjqi	221	9	nonbleeding	nonbleede	VBG
cord-017772-zpf1xjqi	221	10	patients	patient	NNS
cord-017772-zpf1xjqi	221	11	in	in	IN
cord-017772-zpf1xjqi	221	12	the	the	DT
cord-017772-zpf1xjqi	221	13	intensive	intensive	JJ
cord-017772-zpf1xjqi	221	14	care	care	NN
cord-017772-zpf1xjqi	221	15	unit	unit	NN
cord-017772-zpf1xjqi	221	16	:	:	:
cord-017772-zpf1xjqi	221	17	benefit	benefit	NN
cord-017772-zpf1xjqi	221	18	or	or	CC
cord-017772-zpf1xjqi	221	19	harm	harm	NN
cord-017772-zpf1xjqi	221	20	?	?	.
cord-017772-zpf1xjqi	222	1	Platelet	platelet	NN
cord-017772-zpf1xjqi	222	2	transfusion	transfusion	NN
cord-017772-zpf1xjqi	222	3	:	:	:
cord-017772-zpf1xjqi	222	4	a	a	DT
cord-017772-zpf1xjqi	222	5	clinical	clinical	JJ
cord-017772-zpf1xjqi	222	6	practice	practice	NN
cord-017772-zpf1xjqi	222	7	guideline	guideline	NN
cord-017772-zpf1xjqi	222	8	from	from	IN
cord-017772-zpf1xjqi	222	9	the	the	DT
cord-017772-zpf1xjqi	222	10	AABB	AABB	NNP
cord-017772-zpf1xjqi	222	11	Comparison	comparison	NN
cord-017772-zpf1xjqi	222	12	of	of	IN
cord-017772-zpf1xjqi	222	13	different	different	JJ
cord-017772-zpf1xjqi	222	14	platelet	platelet	NN
cord-017772-zpf1xjqi	222	15	transfusion	transfusion	NN
cord-017772-zpf1xjqi	222	16	thresholds	threshold	NNS
cord-017772-zpf1xjqi	222	17	prior	prior	RB
cord-017772-zpf1xjqi	222	18	to	to	IN
cord-017772-zpf1xjqi	222	19	insertion	insertion	NN
cord-017772-zpf1xjqi	222	20	of	of	IN
cord-017772-zpf1xjqi	222	21	central	central	JJ
cord-017772-zpf1xjqi	222	22	lines	line	NNS
cord-017772-zpf1xjqi	222	23	in	in	IN
cord-017772-zpf1xjqi	222	24	patients	patient	NNS
cord-017772-zpf1xjqi	222	25	with	with	IN
cord-017772-zpf1xjqi	222	26	thrombocytopenia	thrombocytopenia	NN
cord-017772-zpf1xjqi	222	27	Complications	complication	NNS
cord-017772-zpf1xjqi	222	28	of	of	IN
cord-017772-zpf1xjqi	222	29	thoracentesis	thoracentesis	NN
cord-017772-zpf1xjqi	222	30	:	:	:
cord-017772-zpf1xjqi	222	31	incidence	incidence	NN
cord-017772-zpf1xjqi	222	32	,	,	,
cord-017772-zpf1xjqi	222	33	risk	risk	NN
cord-017772-zpf1xjqi	222	34	factors	factor	NNS
cord-017772-zpf1xjqi	222	35	,	,	,
cord-017772-zpf1xjqi	222	36	and	and	CC
cord-017772-zpf1xjqi	222	37	strategies	strategy	NNS
cord-017772-zpf1xjqi	222	38	for	for	IN
cord-017772-zpf1xjqi	222	39	prevention	prevention	NN