id author title date pages extension mime words sentences flesch summary cache txt cord-354167-j6l3hq1h Algassim, Abdulrahman A. Prognostic significance of hemoglobin level and autoimmune hemolytic anemia in SARS-CoV-2 infection 2020-09-12 .txt text/plain 3638 205 54 In a disease where there are acute inflammation and compromised oxygenation, we investigated the impact of initial hemoglobin (Hgb) levels at Emergency Department (ED) triage on the severity and the clinical course of COVID-19. All COVID-19 patients admitted to the hospital with at least one anemic reading (Hgb < 12.5 g/dL) and higher than normal LDH levels were screened for IgG and C3 DAT using ORTHO VISIONĀ® MAX Analyzer from Ortho Clinical Diagnostics (Raritan, NJ). In a total of 601 adult patients confirmed by PCR to be infected with SARS-CoV-2 ( Fig. 1) , the mean Hgb level at ED triage for patients requiring admission was significantly lower than that of patients sent to hotel isolation (13.08 g/dL vs. In COVID-19 patients, there is also a higher propensity to bleed due to either iatrogenic anticoagulation or DIC; both can be additional contributing factors for the decrease of Hgb. Since ICU patients have a deeper decline in Hgb, our data suggests that the drop is related to the severity of inflammation associated with SARS-CoV-2 infection. ./cache/cord-354167-j6l3hq1h.txt ./txt/cord-354167-j6l3hq1h.txt