id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-318920-njurbf3d	Romana Ponziani, Francesca	Liver involvement is not associated with mortality: results from a large cohort of SARS‐CoV‐2 positive patients	2020-07-06		.txt	text/plain	2267	131	50	CONCLUSIONS: In SARS‐CoV‐2 positive patients without pre‐existing severe chronic liver disease, baseline liver tests abnormalities are associated with the risk of ICU admission and tend to normalize over time. To investigate the prevalence of liver damage in our cohort of patients, serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT), gamma glutamyl transferase (GGT), alkaline phosphatase (ALP), total bilirubin and albumin were collected at baseline, then on the date closest to 15 days from the admission. This study demonstrates that in patients without severe chronic liver disease liver involvement during SARS-CoV-2 infection is usually mild, is not associated with increased risk of ICU admission or mortality, and tends to resolve over time. Baseline liver tests abnormalities can be found in more than 30% of cases, especially in patients with ARDS; these alterations are associated with the risk of ICU admission but not with mortality, and tend to normalize over time.	./cache/cord-318920-njurbf3d.txt	./txt/cord-318920-njurbf3d.txt