id author title date pages extension mime words sentences flesch summary cache txt cord-031327-uhrkb1p6 Koeze, Jacqueline Bundled care in acute kidney injury in critically ill patients, a before-after educational intervention study 2020-09-03 .txt text/plain 3568 201 54 The educational STK bundle consisted of optimizing the fluid balance (based on urine output, serum lactate levels and/or central venous oxygen saturation), discontinuation of diuretics, maintaining a mean arterial pressure of at least 65 mmHg with the potential use of vasopressors and critical evaluation of the indication and dose of nephrotoxic drugs. Serious adverse events defined as ICU mortality, the need for RRT and/or the progression of AKI was observed in 451 patients (33%) in the STK group compared to 375 patients (29%) in the usual care group (RR 1.16, 95% confidence interval CI 1.03-1.3, p < 0.001) ( Table 3) . This study showed that implementation of an educational 'Save the Kidney bundle care in critically ill patients aiming at a reduction of AKI had no beneficial effect on patient outcome when evaluated by a composite of ICU mortality, the need for RRT and AKI progression. ./cache/cord-031327-uhrkb1p6.txt ./txt/cord-031327-uhrkb1p6.txt