id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-353027-bc0un6kb	Ali, Ahmed	Safety and efficacy of attenuated classic and variant 2 infectious bronchitis virus candidate vaccines	2018-08-06		.txt	text/plain	4144	231	54	Virulence of the attenuated viruses was then tested via the ocular route inoculation and the in vivo back passage in day-old SPF chickens. In conclusion, the attenuated strains IBM41, IB2, and IBvar2 are efficient vaccine candidates against currently circulating classic and variant IB viruses, respectively. The first 3 groups were vaccinated via the ocular route with 10 3.5 EID 50 /bird of att-IBM41 virus, att-IB2, and att-IBvar2 viruses, respectively. The 3 viruses (IBV-EG/11539F-2011, IBV-EG/M41-ME01/2011, and Eg/1212B/2012) were successfully adapted to embryonated chicken eggs and showed the typical embryonic changes including dwarfing, stunting, and curling of embryos by the 10th or 14th passages for the classic (IB2 and IBM41) and the variant virus (IBvar2) (data not shown). Recent studies also indicated that the IBV strains circulating in Egypt represent a distinct a Day-old SPF chicks received 10 4 EID 50 /bird of the attenuated viruses separately via the ocular route.	./cache/cord-353027-bc0un6kb.txt	./txt/cord-353027-bc0un6kb.txt